Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_J11
(422 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99NB9|SF3B1_MOUSE Splicing factor 3B subunit 1 (Spliceo... 208 3e-54
sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 (Spliceo... 208 3e-54
sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1 (Spliceo... 207 7e-54
sp|Q10178|SF3B1_SCHPO U2 snRNP component prp10 170 1e-42
sp|P49955|S3B1_YEAST U2 snRNP component HSH155 152 2e-37
sp|Q9UNS2|CSN3_HUMAN COP9 signalosome complex subunit 3 (Si... 32 0.55
sp|O88543|CSN3_MOUSE COP9 signalosome complex subunit 3 (Si... 32 0.55
sp|Q6P2U9|CSN3_BRARE COP9 signalosome complex subunit 3 (Si... 32 0.55
sp|P03193|UL52_EBV Helicase/primase complex protein (Probab... 30 1.6
sp|O93308|SMC1A_XENLA Structural maintenance of chromosome ... 30 2.1
>sp|Q99NB9|SF3B1_MOUSE Splicing factor 3B subunit 1 (Spliceosome associated protein 155)
(SAP 155) (SF3b155) (Pre-mRNA splicing factor SF3b 155
kDa subunit)
Length = 1304
Score = 208 bits (530), Expect = 3e-54
Identities = 98/140 (70%), Positives = 117/140 (83%)
Frame = +3
Query: 3 RVPDLNVQNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMA 182
RVP+LNVQNGVLKSLSF+FEYIGEM KDYIYAV PLLEDAL+DRDLVHRQTA + V HM+
Sbjct: 1137 RVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMS 1196
Query: 183 LGVYGYGCEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCH 362
LGVYG+GCED+L HLLN VWPNV ETSPH++QA + +E +RV+ G +L Y LQGL H
Sbjct: 1197 LGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFH 1256
Query: 363 PARKITDMMCKIYNALYIAN 422
PARK+ D+ KIYN++YI +
Sbjct: 1257 PARKVRDVYWKIYNSIYIGS 1276
>sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 (Spliceosome associated protein 155)
(SAP 155) (SF3b155) (Pre-mRNA splicing factor SF3b 155
kDa subunit)
Length = 1304
Score = 208 bits (530), Expect = 3e-54
Identities = 98/140 (70%), Positives = 117/140 (83%)
Frame = +3
Query: 3 RVPDLNVQNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMA 182
RVP+LNVQNGVLKSLSF+FEYIGEM KDYIYAV PLLEDAL+DRDLVHRQTA + V HM+
Sbjct: 1137 RVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMS 1196
Query: 183 LGVYGYGCEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCH 362
LGVYG+GCED+L HLLN VWPNV ETSPH++QA + +E +RV+ G +L Y LQGL H
Sbjct: 1197 LGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFH 1256
Query: 363 PARKITDMMCKIYNALYIAN 422
PARK+ D+ KIYN++YI +
Sbjct: 1257 PARKVRDVYWKIYNSIYIGS 1276
>sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1 (Spliceosome associated protein 155)
(SAP 155) (SF3b155) (Pre-mRNA splicing factor SF3b 155
kDa subunit) (146 kDa nuclear protein)
Length = 1307
Score = 207 bits (527), Expect = 7e-54
Identities = 97/140 (69%), Positives = 117/140 (83%)
Frame = +3
Query: 3 RVPDLNVQNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMA 182
RVP+LNVQNGVLKSLSF+FEYIGEM KDYIYAV PLLEDAL+DRDLVHRQTA + V HM+
Sbjct: 1140 RVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMS 1199
Query: 183 LGVYGYGCEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCH 362
LGVYG+GCED+L HLLN VWPNV ETSPH++QA + +E +RV+ G ++ Y LQGL H
Sbjct: 1200 LGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMVQYCLQGLFH 1259
Query: 363 PARKITDMMCKIYNALYIAN 422
PARK+ D+ KIYN++YI +
Sbjct: 1260 PARKVRDVYWKIYNSIYIGS 1279
>sp|Q10178|SF3B1_SCHPO U2 snRNP component prp10
Length = 1188
Score = 170 bits (431), Expect = 1e-42
Identities = 75/138 (54%), Positives = 104/138 (75%)
Frame = +3
Query: 3 RVPDLNVQNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMA 182
R P++NVQNGVLKSL+FMFEYIGE A+DY+YA+ PLL DAL+DRD VHRQTA S + H++
Sbjct: 1021 RTPEMNVQNGVLKSLAFMFEYIGEQARDYVYAITPLLADALMDRDAVHRQTAASVIKHLS 1080
Query: 183 LGVYGYGCEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCH 362
LG G G EDA++HLLN +WPN+LE SPH++ A + ++ +R G ++ Y++QGL H
Sbjct: 1081 LGCVGLGVEDAMIHLLNILWPNILEESPHVINAVREGIDGIRNCIGVGPIMAYLVQGLFH 1140
Query: 363 PARKITDMMCKIYNALYI 416
P+RK+ + YN+ Y+
Sbjct: 1141 PSRKVRNTYWTSYNSAYV 1158
>sp|P49955|S3B1_YEAST U2 snRNP component HSH155
Length = 971
Score = 152 bits (385), Expect = 2e-37
Identities = 69/136 (50%), Positives = 96/136 (70%)
Frame = +3
Query: 9 PDLNVQNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALG 188
P+ NVQNGVLK++SFMFEYIG M+KDYIY + PLLEDAL DRDLVHRQTA + + H+AL
Sbjct: 808 PETNVQNGVLKAMSFMFEYIGNMSKDYIYFITPLLEDALTDRDLVHRQTASNVITHLALN 867
Query: 189 VYGYGCEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCHPA 368
G G EDA +HL+N + PN+ ETSPH + ++ +E++ + G + Y+ GL HPA
Sbjct: 868 CSGTGHEDAFIHLMNLLIPNIFETSPHAIMRILEGLEALSQALGPGLFMNYIWAGLFHPA 927
Query: 369 RKITDMMCKIYNALYI 416
+ + ++YN +Y+
Sbjct: 928 KNVRKAFWRVYNNMYV 943
>sp|Q9UNS2|CSN3_HUMAN COP9 signalosome complex subunit 3 (Signalosome subunit 3) (SGN3)
(JAB1-containing signalosome subunit 3)
Length = 423
Score = 32.0 bits (71), Expect = 0.55
Identities = 15/52 (28%), Positives = 25/52 (48%)
Frame = +2
Query: 260 VSSYCASVCSMCRIYACLLWFNNSAPVCIARVVPSCKENHRYDVQNLQCLIY 415
++S A +C +C + C F + P ++ CKEN YD ++ C Y
Sbjct: 138 LTSIHADLCQLCLLAKC---FKPALPYLDVDMMDICKENGAYDAKHFLCYYY 186
>sp|O88543|CSN3_MOUSE COP9 signalosome complex subunit 3 (Signalosome subunit 3) (SGN3)
(JAB1-containing signalosome subunit 3)
Length = 423
Score = 32.0 bits (71), Expect = 0.55
Identities = 15/52 (28%), Positives = 25/52 (48%)
Frame = +2
Query: 260 VSSYCASVCSMCRIYACLLWFNNSAPVCIARVVPSCKENHRYDVQNLQCLIY 415
++S A +C +C + C F + P ++ CKEN YD ++ C Y
Sbjct: 138 LTSVHADLCQLCLLAKC---FKPALPYLDVDMMDICKENGAYDAKHFLCYYY 186
>sp|Q6P2U9|CSN3_BRARE COP9 signalosome complex subunit 3 (Signalosome subunit 3)
Length = 423
Score = 32.0 bits (71), Expect = 0.55
Identities = 15/52 (28%), Positives = 25/52 (48%)
Frame = +2
Query: 260 VSSYCASVCSMCRIYACLLWFNNSAPVCIARVVPSCKENHRYDVQNLQCLIY 415
++S A +C +C + C F + P ++ CKEN YD ++ C Y
Sbjct: 138 LTSVHADLCQLCLLAKC---FKPAVPFLELDMMDICKENGAYDAKHFLCYYY 186
>sp|P03193|UL52_EBV Helicase/primase complex protein (Probable DNA replication protein
BSLF1)
Length = 874
Score = 30.4 bits (67), Expect = 1.6
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +3
Query: 15 LNVQNGVLKSLSFMFEYIGEMA-KDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGV 191
LN+QN + SL ++G A K + Y +A D LI R R+T V ++ +
Sbjct: 674 LNIQNLLHHSL-----HVGWPAPKTFCYHIADDGRDYLIQRT---RETLPPTVENVCAMI 725
Query: 192 YGYGCEDALVHLLNCVWPNVLET 260
G+ D + + +C+WP+++ T
Sbjct: 726 EGHLGLDLVAWVSSCIWPSLMST 748
>sp|O93308|SMC1A_XENLA Structural maintenance of chromosome 1 protein (xSMC1)
Length = 1232
Score = 30.0 bits (66), Expect = 2.1
Identities = 12/36 (33%), Positives = 21/36 (58%)
Frame = -3
Query: 291 IEQTLAQYEETFQEHLATHNSINEPTHLRNHIHTPL 184
I++T+AQ ++ +HLA + +N+ HL I L
Sbjct: 863 IDETMAQLQDLKNQHLAKKSEVNDKNHLMEDIRKKL 898
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,670,241
Number of Sequences: 369166
Number of extensions: 1115580
Number of successful extensions: 2873
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2810
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2869
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 2052714815
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)