Planaria EST Database


DrC_00117

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00117
         (849 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9BY32|ITPA_HUMAN  Inosine triphosphate pyrophosphatase (...   127   5e-29
sp|Q9D892|ITPA_MOUSE  Inosine triphosphate pyrophosphatase (...   123   6e-28
sp|P47119|HAM1_YEAST  HAM1 protein                                101   2e-21
sp|Q57679|NTPA_METJA  Nucleoside-triphosphatase (Nucleoside ...    85   3e-16
sp|Q8TV07|HAM1_METKA  HAM1 protein homolog                         79   1e-14
sp|Q5JEX8|HAM1_PYRKO  HAM1 protein homolog                         73   1e-12
sp|Q8TJS1|HAM1_METAC  HAM1 protein homolog                         71   4e-12
sp|Q8A327|HAM1_BACTN  HAM1 protein homolog                         70   1e-11
sp|Q8U446|HAM1_PYRFU  HAM1 protein homolog                         69   1e-11
sp|Q8PZ91|HAM1_METMA  HAM1 protein homolog                         68   3e-11
>sp|Q9BY32|ITPA_HUMAN Inosine triphosphate pyrophosphatase (ITPase) (Inosine
           triphosphatase) (Putative oncogene protein hlc14-06-p)
          Length = 194

 Score =  127 bits (318), Expect = 5e-29
 Identities = 73/164 (44%), Positives = 96/164 (58%)
 Frame = +2

Query: 275 IMSQSIDIPEYQEEIIEISLLKAKYAYSIIKEPVFVEDTSLCFNALYGMPGPYIKWFVHG 454
           +++Q ID+PEYQ E  EIS+ K + A   ++ PV VEDT LCFNAL G+PGPYIKWF+  
Sbjct: 35  LVAQKIDLPEYQGEPDEISIQKCQEAVRQVQGPVLVEDTCLCFNALGGLPGPYIKWFL-- 92

Query: 455 NLDEKFKKLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFIGKMLGEIVEPRGPMD 634
              EK K  +GL ++L GF D  A A+   +       Q  + F G+  G IV PRG  D
Sbjct: 93  ---EKLKP-EGLHQLLAGFEDKSAYALCTFALSTGDPSQPVRLFRGRTSGRIVAPRGCQD 148

Query: 635 FDWDCVFQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEFKKF 766
           F WD  FQP        QTYAEM    KN +S+R+ A  E +++
Sbjct: 149 FGWDPCFQP----DGYEQTYAEMPKAEKNAVSHRFRALLELQEY 188
>sp|Q9D892|ITPA_MOUSE Inosine triphosphate pyrophosphatase (ITPase) (Inosine
           triphosphatase)
          Length = 198

 Score =  123 bits (309), Expect = 6e-28
 Identities = 72/162 (44%), Positives = 94/162 (58%)
 Frame = +2

Query: 281 SQSIDIPEYQEEIIEISLLKAKYAYSIIKEPVFVEDTSLCFNALYGMPGPYIKWFVHGNL 460
           +Q ID+PEYQ E  EIS+ K + A   ++ PV VEDT LCFNAL G+PGPYIKWF+    
Sbjct: 37  AQKIDLPEYQGEPDEISIQKCREAARQVQGPVLVEDTCLCFNALGGLPGPYIKWFL---- 92

Query: 461 DEKFKKLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFIGKMLGEIVEPRGPMDFD 640
            +K K  +GL ++L GF D  A A+   +       Q    F G+  G+IV PRG  DF 
Sbjct: 93  -QKLKP-EGLHQLLAGFEDKSAYALCTFALSTGDPSQPVLLFRGQTSGQIVMPRGSRDFG 150

Query: 641 WDCVFQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEFKKF 766
           WD  FQP        QTYAEM    KN IS+R+ A  + +++
Sbjct: 151 WDPCFQP----DGYEQTYAEMPKSEKNTISHRFRALHKLQEY 188
>sp|P47119|HAM1_YEAST HAM1 protein
          Length = 197

 Score =  101 bits (252), Expect = 2e-21
 Identities = 66/171 (38%), Positives = 98/171 (57%), Gaps = 3/171 (1%)
 Frame = +2

Query: 275 IMSQSIDIPEYQE-EIIEISLLKAKYAYSIIKE--PVFVEDTSLCFNALYGMPGPYIKWF 445
           ++++++D+ E Q+ ++  I+L K K A + + +  PVFVEDT+L F+   G+PG YIKWF
Sbjct: 36  LINEALDLEELQDTDLNAIALAKGKQAVAALGKGKPVFVEDTALRFDEFNGLPGAYIKWF 95

Query: 446 VHGNLDEKFKKLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFIGKMLGEIVEPRG 625
           +      K   L+ + KML  F +  AEAVT I + D +   +   F G   G+IV  RG
Sbjct: 96  L------KSMGLEKIVKMLEPFENKNAEAVTTICFADSR--GEYHFFQGITRGKIVPSRG 147

Query: 626 PMDFDWDCVFQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEFKKFLLEN 778
           P  F WD +F+P         TYAEM    KN IS+R  A  +FK++L +N
Sbjct: 148 PTTFGWDSIFEPF---DSHGLTYAEMSKDAKNAISHRGKAFAQFKEYLYQN 195
>sp|Q57679|NTPA_METJA Nucleoside-triphosphatase (Nucleoside triphosphate
           phosphohydrolase) (NTPase)
          Length = 193

 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 56/162 (34%), Positives = 89/162 (54%)
 Frame = +2

Query: 290 IDIPEYQEEIIEISLLKAKYAYSIIKEPVFVEDTSLCFNALYGMPGPYIKWFVHGNLDEK 469
           I  PE Q  + E++   AK+ Y+I+K+PV VED+     AL G PG Y K FV   +   
Sbjct: 41  ISYPEIQGTLEEVAEFGAKWVYNILKKPVIVEDSGFFVEALNGFPGTYSK-FVQETIGN- 98

Query: 470 FKKLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFIGKMLGEIVEPRGPMDFDWDC 649
               +G+ K+L G ++  A   T+I Y D   ++  K  +   + E +  +G   F +D 
Sbjct: 99  ----EGILKLLEGKDNRNAYFKTVIGYCDENGVRLFKGIVKGRVSEEIRSKG-YGFAYDS 153

Query: 650 VFQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEFKKFLLE 775
           +F P    ++  +T+AEM  + K++IS+R  A +EFKKFLL+
Sbjct: 154 IFIP----EEEERTFAEMTTEEKSQISHRKKAFEEFKKFLLD 191
>sp|Q8TV07|HAM1_METKA HAM1 protein homolog
          Length = 188

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 55/167 (32%), Positives = 86/167 (51%), Gaps = 4/167 (2%)
 Frame = +2

Query: 290 IDIPEYQEEIIE-ISLLKAKYAYSIIKEPVFVEDTSLCFNALYGMPGPYIKWFVH--GNL 460
           +D PE Q + +E I+   A+Y    + +PV VED+ L   AL G PGPY  +     GN 
Sbjct: 32  LDYPELQSDSLEEIAAYGARYCAESLGQPVIVEDSGLFIEALNGFPGPYSAYVFDTIGN- 90

Query: 461 DEKFKKLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFIGKMLGEIV-EPRGPMDF 637
                  +G+ K+L G  + +AE ++++ Y +P     P  F G++ G I  EPRG   F
Sbjct: 91  -------EGILKLLEGEENRKAEFISVVGYCEPG--GRPVTFTGEIRGRIAEEPRGEEGF 141

Query: 638 DWDCVFQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEFKKFLLEN 778
            +D +F P  +      T+AE+  + K KIS+R  A + F ++   N
Sbjct: 142 GYDPIFIPEGED----STFAELGVEEKCKISHRTKALERFAEWYKNN 184
>sp|Q5JEX8|HAM1_PYRKO HAM1 protein homolog
          Length = 184

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 53/165 (32%), Positives = 87/165 (52%), Gaps = 2/165 (1%)
 Frame = +2

Query: 290 IDIPEYQEEIIE-ISLLKAKYAYSIIKEPVFVEDTSLCFNALYGMPGPYIKWFVHGNLDE 466
           +  PE Q + +E ++   AK+    +  P F++D+ L   AL G PG Y  +        
Sbjct: 32  VSYPEIQADTLEEVAEYGAKWLAQRVDGPFFLDDSGLFVEALKGFPGVYSAYVY------ 85

Query: 467 KFKKLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFIGKMLGEIV-EPRGPMDFDW 643
           K    QG+ K+L G  + +A   ++I+Y+D ++      F G++ G+I  EPRG   F +
Sbjct: 86  KTIGYQGILKLLQGEKNRKAHFKSVIAYWDGEL----HIFTGRVDGKIATEPRGSGGFGF 141

Query: 644 DCVFQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEFKKFLLEN 778
           D +F P    +   +T+AEM  + KN+IS+R  A +EF  +L EN
Sbjct: 142 DPIFIP----EGFDRTFAEMTTEEKNRISHRGRALREFANWLKEN 182
>sp|Q8TJS1|HAM1_METAC HAM1 protein homolog
          Length = 184

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 53/163 (32%), Positives = 85/163 (52%), Gaps = 2/163 (1%)
 Frame = +2

Query: 275 IMSQSIDIPEYQEEIIE-ISLLKAKYAYSIIKEPVFVEDTSLCFNALYGMPGPYIKWFVH 451
           ++ +    PE QE+ +E I+   A+Y  + +  PV V+D+ +  NAL G PGPY ++   
Sbjct: 28  VIQEKNGYPELQEDELEPIAAHGAQYVANKLNMPVMVDDSGIFINALNGFPGPYSRF--- 84

Query: 452 GNLDEKFKKLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFIGKMLGEIV-EPRGP 628
             +++K   L+ L KM+ G  D  A   T+I Y +P   ++P  F G + G+I  E RG 
Sbjct: 85  --VEDKLGNLKVL-KMMEGEEDRTAYFKTVIGYCEPG--KEPLVFPGVVEGKIAYEERGT 139

Query: 629 MDFDWDCVFQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEF 757
             F +D +F+          T+ E+    KNK+S+R  A  EF
Sbjct: 140 GGFGYDPIFEYQG------LTFGELGDTEKNKVSHRRRAVDEF 176
>sp|Q8A327|HAM1_BACTN HAM1 protein homolog
          Length = 193

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 54/162 (33%), Positives = 83/162 (51%), Gaps = 3/162 (1%)
 Frame = +2

Query: 293 DIPEYQEEIIEISLLKAKYAYSIIKEPVFVEDTSLCFNALYGMPGPYIKWFVHGNLDEKF 472
           DIPE  E +   +LLK+ + Y   +   F +DT L   AL G PG Y   +  G   +  
Sbjct: 39  DIPETAETLEGNALLKSSFIYRNYQLDCFADDTGLEVEALNGAPGVYSARYAEGEGHDAQ 98

Query: 473 KKLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFI--GKMLGEIV-EPRGPMDFDW 643
             ++ L   L G  + +A+  T IS     ++ D K ++  G + GEI+ E RG   F +
Sbjct: 99  ANMRKLLHELEGKENRKAQFRTAIS-----LILDGKEYLFEGVIKGEIIKEKRGDSGFGY 153

Query: 644 DCVFQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEFKKFL 769
           D +F+P    +   QT+AE+  + KNKIS+R  A Q+  +FL
Sbjct: 154 DPIFKP----EGYEQTFAELGNETKNKISHRALAVQKLCEFL 191
>sp|Q8U446|HAM1_PYRFU HAM1 protein homolog
          Length = 185

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 48/170 (28%), Positives = 86/170 (50%), Gaps = 2/170 (1%)
 Frame = +2

Query: 275 IMSQSIDIPEYQEEIIE-ISLLKAKYAYSIIKEPVFVEDTSLCFNALYGMPGPYIKWFVH 451
           ++ + ++ PE Q + +E + +    +    + +P  +ED+ L   AL G PG Y  +   
Sbjct: 27  VIKKPLEYPEIQADTLEDVVVFGLNWLKDKVDKPFIIEDSGLFIEALNGFPGVYSAYVY- 85

Query: 452 GNLDEKFKKLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFIGKMLGEIV-EPRGP 628
                K   L G+ K++ G  + +A   ++I +YD +I      F+G++ G I  E RG 
Sbjct: 86  -----KTIGLDGILKLMEGIENRKAYFKSVIGFYDGEI----HLFVGEVRGRISNEKRGL 136

Query: 629 MDFDWDCVFQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEFKKFLLEN 778
             F +D +F P        +T+AEM  + KN +S+R  A +EF +++ EN
Sbjct: 137 HGFGYDPIFVP----DGFDKTFAEMSTEEKNSVSHRGKALKEFYRWMKEN 182
>sp|Q8PZ91|HAM1_METMA HAM1 protein homolog
          Length = 184

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 52/160 (32%), Positives = 81/160 (50%), Gaps = 2/160 (1%)
 Frame = +2

Query: 299 PEYQEEIIE-ISLLKAKYAYSIIKEPVFVEDTSLCFNALYGMPGPYIKWFVHGNLDEKFK 475
           PE QE+ +E I+   A+Y  + +  PV V+D+ +  NAL G PGPY + FV   L     
Sbjct: 36  PELQEDELEPIAANGAQYVANKLNMPVMVDDSGIFINALNGFPGPYSR-FVEDKLGN--- 91

Query: 476 KLQGLRKMLVGFNDFRAEAVTIISYYDPKIMQDPKAFIGKMLGEIV-EPRGPMDFDWDCV 652
               + K++ G  D  A   T+I Y +P   Q+P  F G + G+I  E RG   F +D +
Sbjct: 92  --PKVLKLMEGEKDRSAYFKTVIGYCEPG--QEPLVFPGVVEGKIAYEERGTGGFGYDPI 147

Query: 653 FQPVAQCQDTLQTYAEMDYKYKNKISNRYNAAQEFKKFLL 772
           F+          T+ E+  + KNK+S+R  A   F ++ +
Sbjct: 148 FEYNG------MTFGELGDEEKNKVSHRRRAVDNFLEWFI 181
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,541,649
Number of Sequences: 369166
Number of extensions: 1694532
Number of successful extensions: 3761
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3640
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3732
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00117

  1. Dr_sW_003_P06
  2. Dr_sW_015_K03
  3. Dr_sW_008_P04