Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00105 (797 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9NVA2|SEP11_HUMAN Septin-11 141 2e-33 sp|Q5R8U3|SEP11_PONPY Septin-11 141 2e-33 sp|P54359|SEPT2_DROME Septin-2 140 4e-33 sp|Q9R1T4|SEPT6_MOUSE Septin-6 139 7e-33 sp|Q8C1B7|SEP11_MOUSE Septin-11 139 9e-33 sp|Q14141|SEPT6_HUMAN Septin-6 137 3e-32 sp|Q92599|SEPT8_HUMAN Septin-8 130 4e-30 sp|Q8CHH9|SEPT8_MOUSE Septin-8 127 4e-29 sp|Q5PQK1|SEP10_RAT Septin-10 127 5e-29 sp|Q8C650|SEP10_MOUSE Septin-10 126 6e-29
>sp|Q9NVA2|SEP11_HUMAN Septin-11 Length = 429 Score = 141 bits (355), Expect = 2e-33 Identities = 77/183 (42%), Positives = 108/183 (59%), Gaps = 8/183 (4%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS +E K+ N K+++ RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE Sbjct: 238 GSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYEL 296 Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ +L EMGF D++ SL +RQMF +RVKEKE +L Sbjct: 297 YRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAEL 356 Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE----QAKQGNTIK 517 KE++KEL KF+ LK+++ NNF+K+KA + QA+Q + Sbjct: 357 KEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQ 416 Query: 518 KKK 526 KK Sbjct: 417 TKK 419
>sp|Q5R8U3|SEP11_PONPY Septin-11 Length = 425 Score = 141 bits (355), Expect = 2e-33 Identities = 77/183 (42%), Positives = 108/183 (59%), Gaps = 8/183 (4%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS +E K+ N K+++ RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE Sbjct: 238 GSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYEL 296 Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ +L EMGF D++ SL +RQMF +RVKEKE +L Sbjct: 297 YRRCKLEEMGFKDTDPDSKPFSLQETYKAKRNEFLGELQKKEEEMRQMFVMRVKEKEAEL 356 Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE----QAKQGNTIK 517 KE++KEL KF+ LK+++ NNF+K+KA + QA+Q + Sbjct: 357 KEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQ 416 Query: 518 KKK 526 KK Sbjct: 417 TKK 419
>sp|P54359|SEPT2_DROME Septin-2 Length = 419 Score = 140 bits (353), Expect = 4e-33 Identities = 77/179 (43%), Positives = 105/179 (58%), Gaps = 4/179 (2%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS + K+ N K+ R RQYPWGTVQ++NE HCDF++LR+ML+RTNM+D+RE+TH HYE Sbjct: 240 GSTEFIKVGN-KLIRARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYEL 298 Query: 182 YRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ RL +MGF SDN+ +S +RQMF RVKEKE +L Sbjct: 299 YRQKRLEQMGFSDVDSDNKPISFQQTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAEL 358 Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVEQAKQGNTIKKKK 526 KES+K+L +KFE LK+ +A +F++RK + A T+ K K Sbjct: 359 KESEKDLHAKFEKLKRDHAEEKRKLEESRKALEEDYLDFQRRKQQLATAHHTLTLGKSK 417
>sp|Q9R1T4|SEPT6_MOUSE Septin-6 Length = 434 Score = 139 bits (351), Expect = 7e-33 Identities = 80/186 (43%), Positives = 105/186 (56%), Gaps = 11/186 (5%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS +E K+ N K+ R RQYPWGTVQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE Sbjct: 239 GSTEEVKIGN-KMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHARHYEL 297 Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ +L EMGF D++ SL +RQMF RVKEKE +L Sbjct: 298 YRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAEL 357 Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE-------QAKQGN 508 KE++KEL KF+ LKK + N F++RKA E QA Sbjct: 358 KEAEKELHEKFDRLKKLHQEEKKKLEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQ 417 Query: 509 TIKKKK 526 T+K+ K Sbjct: 418 TLKRDK 423
>sp|Q8C1B7|SEP11_MOUSE Septin-11 Length = 431 Score = 139 bits (350), Expect = 9e-33 Identities = 76/183 (41%), Positives = 108/183 (59%), Gaps = 8/183 (4%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS +E K+ N K+++ RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE Sbjct: 238 GSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYEL 296 Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ +L EMGF D++ SL +RQMF +RVKEKE +L Sbjct: 297 YRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAEL 356 Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE----QAKQGNTIK 517 KE++KEL KF+ LK+++ +NF+K+KA + QA+Q + Sbjct: 357 KEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSGAQQ 416 Query: 518 KKK 526 KK Sbjct: 417 TKK 419
>sp|Q14141|SEPT6_HUMAN Septin-6 Length = 434 Score = 137 bits (346), Expect = 3e-32 Identities = 79/186 (42%), Positives = 104/186 (55%), Gaps = 11/186 (5%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS +E K+ N K+ R RQYPWGTVQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE Sbjct: 239 GSTEELKIGN-KMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYEL 297 Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ +L EMGF D++ SL +RQMF RVKEKE +L Sbjct: 298 YRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAEL 357 Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE-------QAKQGN 508 KE++KEL KF+ LKK + N F++RK E QA Sbjct: 358 KEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQ 417 Query: 509 TIKKKK 526 T+K+ K Sbjct: 418 TLKRDK 423
>sp|Q92599|SEPT8_HUMAN Septin-8 Length = 483 Score = 130 bits (327), Expect = 4e-30 Identities = 72/167 (43%), Positives = 95/167 (56%), Gaps = 4/167 (2%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS +E K+ N K+ R RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE Sbjct: 241 GSTEEVKVGN-KLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYEL 299 Query: 182 YRKHRLIEMGFSDNEN----MSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ +L EMGF D++ SL +RQMF +VKE E +L Sbjct: 300 YRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELEL 359 Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE 490 KE ++EL KFE LK+ + N F +RKA VE Sbjct: 360 KEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVE 406
>sp|Q8CHH9|SEPT8_MOUSE Septin-8 Length = 429 Score = 127 bits (319), Expect = 4e-29 Identities = 71/167 (42%), Positives = 94/167 (56%), Gaps = 4/167 (2%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS +E K+ N K+ R RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE Sbjct: 241 GSTEEVKVGN-KLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYEL 299 Query: 182 YRKHRLIEMGFSDNEN----MSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ +L EMGF D++ SL +RQMF +VKE E +L Sbjct: 300 YRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELEL 359 Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE 490 KE ++EL KFE LK+ + N F RKA +E Sbjct: 360 KEKERELHEKFEHLKRIHQEEKRKVEEKRRELEEETNAFNCRKAAME 406
>sp|Q5PQK1|SEP10_RAT Septin-10 Length = 456 Score = 127 bits (318), Expect = 5e-29 Identities = 67/136 (49%), Positives = 90/136 (66%), Gaps = 4/136 (2%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS DE K+ N K+ + RQYPWG VQ++NE HCDF++LR+ML+ TNM+DLRE+TH+ HYE Sbjct: 240 GSMDEIKVGN-KMVKARQYPWGIVQVENENHCDFVKLREMLICTNMEDLREQTHMRHYEL 298 Query: 182 YRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ +L EMGF D N+ +SL ++QMF RVKEKE L Sbjct: 299 YRRCKLQEMGFIDIGPENKPLSLQETYEAKRHEFCGERQRKEEQMKQMFVQRVKEKEAIL 358 Query: 350 KESDKELLSKFETLKK 397 KE+++EL +KFE LK+ Sbjct: 359 KEAERELQAKFEHLKR 374
>sp|Q8C650|SEP10_MOUSE Septin-10 Length = 452 Score = 126 bits (317), Expect = 6e-29 Identities = 76/185 (41%), Positives = 104/185 (56%), Gaps = 10/185 (5%) Frame = +2 Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181 GS DE K+ N K+ + RQYPWG VQ++NE HCDF++LR+ML+ TNM+DLRE+TH+ HYE Sbjct: 236 GSMDEIKVGN-KMVKGRQYPWGIVQVENENHCDFVKLREMLICTNMEDLREQTHMRHYEL 294 Query: 182 YRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349 YR+ +L EMGF D N+ +SL ++QMF RVKEKE L Sbjct: 295 YRRCKLQEMGFVDMGPENKPLSLQETYEAKRHEFYGERQRKEEQMKQMFVQRVKEKEAIL 354 Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVEQ------AKQGNT 511 KE+++EL +KFE LK+ + F K+KA E G++ Sbjct: 355 KEAERELQAKFEHLKRIHQEERMKLEEKRRMLEEESVAFAKKKATCELFPNQSFLASGSS 414 Query: 512 IKKKK 526 I+K K Sbjct: 415 IRKDK 419
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 71,545,036 Number of Sequences: 369166 Number of extensions: 1133854 Number of successful extensions: 2892 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2752 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2871 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7522142940 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)