Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_L13
(797 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NVA2|SEP11_HUMAN Septin-11 141 2e-33
sp|Q5R8U3|SEP11_PONPY Septin-11 141 2e-33
sp|P54359|SEPT2_DROME Septin-2 140 4e-33
sp|Q9R1T4|SEPT6_MOUSE Septin-6 139 7e-33
sp|Q8C1B7|SEP11_MOUSE Septin-11 139 9e-33
sp|Q14141|SEPT6_HUMAN Septin-6 137 3e-32
sp|Q92599|SEPT8_HUMAN Septin-8 130 4e-30
sp|Q8CHH9|SEPT8_MOUSE Septin-8 127 4e-29
sp|Q5PQK1|SEP10_RAT Septin-10 127 5e-29
sp|Q8C650|SEP10_MOUSE Septin-10 126 6e-29
>sp|Q9NVA2|SEP11_HUMAN Septin-11
Length = 429
Score = 141 bits (355), Expect = 2e-33
Identities = 77/183 (42%), Positives = 108/183 (59%), Gaps = 8/183 (4%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS +E K+ N K+++ RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE
Sbjct: 238 GSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYEL 296
Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ +L EMGF D++ SL +RQMF +RVKEKE +L
Sbjct: 297 YRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAEL 356
Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE----QAKQGNTIK 517
KE++KEL KF+ LK+++ NNF+K+KA + QA+Q +
Sbjct: 357 KEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQ 416
Query: 518 KKK 526
KK
Sbjct: 417 TKK 419
>sp|Q5R8U3|SEP11_PONPY Septin-11
Length = 425
Score = 141 bits (355), Expect = 2e-33
Identities = 77/183 (42%), Positives = 108/183 (59%), Gaps = 8/183 (4%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS +E K+ N K+++ RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE
Sbjct: 238 GSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYEL 296
Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ +L EMGF D++ SL +RQMF +RVKEKE +L
Sbjct: 297 YRRCKLEEMGFKDTDPDSKPFSLQETYKAKRNEFLGELQKKEEEMRQMFVMRVKEKEAEL 356
Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE----QAKQGNTIK 517
KE++KEL KF+ LK+++ NNF+K+KA + QA+Q +
Sbjct: 357 KEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQ 416
Query: 518 KKK 526
KK
Sbjct: 417 TKK 419
>sp|P54359|SEPT2_DROME Septin-2
Length = 419
Score = 140 bits (353), Expect = 4e-33
Identities = 77/179 (43%), Positives = 105/179 (58%), Gaps = 4/179 (2%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS + K+ N K+ R RQYPWGTVQ++NE HCDF++LR+ML+RTNM+D+RE+TH HYE
Sbjct: 240 GSTEFIKVGN-KLIRARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYEL 298
Query: 182 YRKHRLIEMGF----SDNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ RL +MGF SDN+ +S +RQMF RVKEKE +L
Sbjct: 299 YRQKRLEQMGFSDVDSDNKPISFQQTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAEL 358
Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVEQAKQGNTIKKKK 526
KES+K+L +KFE LK+ +A +F++RK + A T+ K K
Sbjct: 359 KESEKDLHAKFEKLKRDHAEEKRKLEESRKALEEDYLDFQRRKQQLATAHHTLTLGKSK 417
>sp|Q9R1T4|SEPT6_MOUSE Septin-6
Length = 434
Score = 139 bits (351), Expect = 7e-33
Identities = 80/186 (43%), Positives = 105/186 (56%), Gaps = 11/186 (5%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS +E K+ N K+ R RQYPWGTVQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE
Sbjct: 239 GSTEEVKIGN-KMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHARHYEL 297
Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ +L EMGF D++ SL +RQMF RVKEKE +L
Sbjct: 298 YRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAEL 357
Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE-------QAKQGN 508
KE++KEL KF+ LKK + N F++RKA E QA
Sbjct: 358 KEAEKELHEKFDRLKKLHQEEKKKLEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQ 417
Query: 509 TIKKKK 526
T+K+ K
Sbjct: 418 TLKRDK 423
>sp|Q8C1B7|SEP11_MOUSE Septin-11
Length = 431
Score = 139 bits (350), Expect = 9e-33
Identities = 76/183 (41%), Positives = 108/183 (59%), Gaps = 8/183 (4%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS +E K+ N K+++ RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE
Sbjct: 238 GSTEEVKIGN-KMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYEL 296
Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ +L EMGF D++ SL +RQMF +RVKEKE +L
Sbjct: 297 YRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAEL 356
Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE----QAKQGNTIK 517
KE++KEL KF+ LK+++ +NF+K+KA + QA+Q +
Sbjct: 357 KEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSGAQQ 416
Query: 518 KKK 526
KK
Sbjct: 417 TKK 419
>sp|Q14141|SEPT6_HUMAN Septin-6
Length = 434
Score = 137 bits (346), Expect = 3e-32
Identities = 79/186 (42%), Positives = 104/186 (55%), Gaps = 11/186 (5%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS +E K+ N K+ R RQYPWGTVQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE
Sbjct: 239 GSTEELKIGN-KMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYEL 297
Query: 182 YRKHRLIEMGFS----DNENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ +L EMGF D++ SL +RQMF RVKEKE +L
Sbjct: 298 YRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAEL 357
Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE-------QAKQGN 508
KE++KEL KF+ LKK + N F++RK E QA
Sbjct: 358 KEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQ 417
Query: 509 TIKKKK 526
T+K+ K
Sbjct: 418 TLKRDK 423
>sp|Q92599|SEPT8_HUMAN Septin-8
Length = 483
Score = 130 bits (327), Expect = 4e-30
Identities = 72/167 (43%), Positives = 95/167 (56%), Gaps = 4/167 (2%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS +E K+ N K+ R RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE
Sbjct: 241 GSTEEVKVGN-KLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYEL 299
Query: 182 YRKHRLIEMGFSDNEN----MSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ +L EMGF D++ SL +RQMF +VKE E +L
Sbjct: 300 YRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELEL 359
Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE 490
KE ++EL KFE LK+ + N F +RKA VE
Sbjct: 360 KEKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVE 406
>sp|Q8CHH9|SEPT8_MOUSE Septin-8
Length = 429
Score = 127 bits (319), Expect = 4e-29
Identities = 71/167 (42%), Positives = 94/167 (56%), Gaps = 4/167 (2%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS +E K+ N K+ R RQYPWG VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE
Sbjct: 241 GSTEEVKVGN-KLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYEL 299
Query: 182 YRKHRLIEMGFSDNEN----MSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ +L EMGF D++ SL +RQMF +VKE E +L
Sbjct: 300 YRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELEL 359
Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVE 490
KE ++EL KFE LK+ + N F RKA +E
Sbjct: 360 KEKERELHEKFEHLKRIHQEEKRKVEEKRRELEEETNAFNCRKAAME 406
>sp|Q5PQK1|SEP10_RAT Septin-10
Length = 456
Score = 127 bits (318), Expect = 5e-29
Identities = 67/136 (49%), Positives = 90/136 (66%), Gaps = 4/136 (2%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS DE K+ N K+ + RQYPWG VQ++NE HCDF++LR+ML+ TNM+DLRE+TH+ HYE
Sbjct: 240 GSMDEIKVGN-KMVKARQYPWGIVQVENENHCDFVKLREMLICTNMEDLREQTHMRHYEL 298
Query: 182 YRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ +L EMGF D N+ +SL ++QMF RVKEKE L
Sbjct: 299 YRRCKLQEMGFIDIGPENKPLSLQETYEAKRHEFCGERQRKEEQMKQMFVQRVKEKEAIL 358
Query: 350 KESDKELLSKFETLKK 397
KE+++EL +KFE LK+
Sbjct: 359 KEAERELQAKFEHLKR 374
>sp|Q8C650|SEP10_MOUSE Septin-10
Length = 452
Score = 126 bits (317), Expect = 6e-29
Identities = 76/185 (41%), Positives = 104/185 (56%), Gaps = 10/185 (5%)
Frame = +2
Query: 2 GSNDEAKMPNGKVSRVRQYPWGTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYET 181
GS DE K+ N K+ + RQYPWG VQ++NE HCDF++LR+ML+ TNM+DLRE+TH+ HYE
Sbjct: 236 GSMDEIKVGN-KMVKGRQYPWGIVQVENENHCDFVKLREMLICTNMEDLREQTHMRHYEL 294
Query: 182 YRKHRLIEMGFSD----NENMSLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQL 349
YR+ +L EMGF D N+ +SL ++QMF RVKEKE L
Sbjct: 295 YRRCKLQEMGFVDMGPENKPLSLQETYEAKRHEFYGERQRKEEQMKQMFVQRVKEKEAIL 354
Query: 350 KESDKELLSKFETLKKSNAXXXXXXXXXXXXXXXXXNNFEKRKAIVEQ------AKQGNT 511
KE+++EL +KFE LK+ + F K+KA E G++
Sbjct: 355 KEAERELQAKFEHLKRIHQEERMKLEEKRRMLEEESVAFAKKKATCELFPNQSFLASGSS 414
Query: 512 IKKKK 526
I+K K
Sbjct: 415 IRKDK 419
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,547,973
Number of Sequences: 369166
Number of extensions: 1133516
Number of successful extensions: 2876
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2738
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2855
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7522142940
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)