Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_O08
(547 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P54359|SEPT2_DROME Septin-2 121 1e-27
sp|Q9NVA2|SEP11_HUMAN Septin-11 118 8e-27
sp|Q5R8U3|SEP11_PONPY Septin-11 118 8e-27
sp|Q9R1T4|SEPT6_MOUSE Septin-6 116 3e-26
sp|Q8C1B7|SEP11_MOUSE Septin-11 116 3e-26
sp|Q14141|SEPT6_HUMAN Septin-6 115 9e-26
sp|Q92599|SEPT8_HUMAN Septin-8 107 1e-23
sp|Q8C650|SEP10_MOUSE Septin-10 105 5e-23
sp|Q5PQK1|SEP10_RAT Septin-10 105 9e-23
sp|Q8CHH9|SEPT8_MOUSE Septin-8 104 1e-22
>sp|P54359|SEPT2_DROME Septin-2
Length = 419
Score = 121 bits (303), Expect = 1e-27
Identities = 66/158 (41%), Positives = 91/158 (57%), Gaps = 4/158 (2%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGF----SDNENM 169
GTVQ++NE HCDF++LR+ML+RTNM+D+RE+TH HYE YR+ RL +MGF SDN+ +
Sbjct: 260 GTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPI 319
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKKSNAXX 349
S +RQMF RVKEKE +LKES+K+L +KFE LK+ +A
Sbjct: 320 SFQQTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEE 379
Query: 350 XXXXXXXXXXXXXXXNNFEKRKAIVEQAKQGNTIKKKK 463
+F++RK + A T+ K K
Sbjct: 380 KRKLEESRKALEEDYLDFQRRKQQLATAHHTLTLGKSK 417
>sp|Q9NVA2|SEP11_HUMAN Septin-11
Length = 429
Score = 118 bits (296), Expect = 8e-27
Identities = 66/162 (40%), Positives = 92/162 (56%), Gaps = 8/162 (4%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFS----DNENM 169
G VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE YR+ +L EMGF D++
Sbjct: 258 GVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPF 317
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKKSNAXX 349
SL +RQMF +RVKEKE +LKE++KEL KF+ LK+++
Sbjct: 318 SLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEE 377
Query: 350 XXXXXXXXXXXXXXXNNFEKRKAIVE----QAKQGNTIKKKK 463
NNF+K+KA + QA+Q + KK
Sbjct: 378 KKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQTKK 419
>sp|Q5R8U3|SEP11_PONPY Septin-11
Length = 425
Score = 118 bits (296), Expect = 8e-27
Identities = 66/162 (40%), Positives = 92/162 (56%), Gaps = 8/162 (4%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFS----DNENM 169
G VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE YR+ +L EMGF D++
Sbjct: 258 GVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPF 317
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKKSNAXX 349
SL +RQMF +RVKEKE +LKE++KEL KF+ LK+++
Sbjct: 318 SLQETYKAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEE 377
Query: 350 XXXXXXXXXXXXXXXNNFEKRKAIVE----QAKQGNTIKKKK 463
NNF+K+KA + QA+Q + KK
Sbjct: 378 KKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQTKK 419
>sp|Q9R1T4|SEPT6_MOUSE Septin-6
Length = 434
Score = 116 bits (291), Expect = 3e-26
Identities = 68/165 (41%), Positives = 90/165 (54%), Gaps = 11/165 (6%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFS----DNENM 169
GTVQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE YR+ +L EMGF D++
Sbjct: 259 GTVQVENEAHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSKPF 318
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKKSNAXX 349
SL +RQMF RVKEKE +LKE++KEL KF+ LKK +
Sbjct: 319 SLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQEE 378
Query: 350 XXXXXXXXXXXXXXXNNFEKRKAIVE-------QAKQGNTIKKKK 463
N F++RKA E QA T+K+ K
Sbjct: 379 KKKLEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQTLKRDK 423
>sp|Q8C1B7|SEP11_MOUSE Septin-11
Length = 431
Score = 116 bits (291), Expect = 3e-26
Identities = 65/162 (40%), Positives = 92/162 (56%), Gaps = 8/162 (4%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFS----DNENM 169
G VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE YR+ +L EMGF D++
Sbjct: 258 GVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPF 317
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKKSNAXX 349
SL +RQMF +RVKEKE +LKE++KEL KF+ LK+++
Sbjct: 318 SLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEE 377
Query: 350 XXXXXXXXXXXXXXXNNFEKRKAIVE----QAKQGNTIKKKK 463
+NF+K+KA + QA+Q + KK
Sbjct: 378 KKKVEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSGAQQTKK 419
>sp|Q14141|SEPT6_HUMAN Septin-6
Length = 434
Score = 115 bits (287), Expect = 9e-26
Identities = 67/165 (40%), Positives = 89/165 (53%), Gaps = 11/165 (6%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFS----DNENM 169
GTVQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE YR+ +L EMGF D++
Sbjct: 259 GTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPF 318
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKKSNAXX 349
SL +RQMF RVKEKE +LKE++KEL KF+ LKK +
Sbjct: 319 SLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDE 378
Query: 350 XXXXXXXXXXXXXXXNNFEKRKAIVE-------QAKQGNTIKKKK 463
N F++RK E QA T+K+ K
Sbjct: 379 KKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDK 423
>sp|Q92599|SEPT8_HUMAN Septin-8
Length = 483
Score = 107 bits (268), Expect = 1e-23
Identities = 60/146 (41%), Positives = 80/146 (54%), Gaps = 4/146 (2%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNEN----M 169
G VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE YR+ +L EMGF D++
Sbjct: 261 GVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPF 320
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKKSNAXX 349
SL +RQMF +VKE E +LKE ++EL KFE LK+ +
Sbjct: 321 SLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEE 380
Query: 350 XXXXXXXXXXXXXXXNNFEKRKAIVE 427
N F +RKA VE
Sbjct: 381 KRKVEEKRRELEEETNAFNRRKAAVE 406
>sp|Q8C650|SEP10_MOUSE Septin-10
Length = 452
Score = 105 bits (263), Expect = 5e-23
Identities = 64/164 (39%), Positives = 89/164 (54%), Gaps = 10/164 (6%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENM 169
G VQ++NE HCDF++LR+ML+ TNM+DLRE+TH+ HYE YR+ +L EMGF D N+ +
Sbjct: 256 GIVQVENENHCDFVKLREMLICTNMEDLREQTHMRHYELYRRCKLQEMGFVDMGPENKPL 315
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKKSNAXX 349
SL ++QMF RVKEKE LKE+++EL +KFE LK+ +
Sbjct: 316 SLQETYEAKRHEFYGERQRKEEQMKQMFVQRVKEKEAILKEAERELQAKFEHLKRIHQEE 375
Query: 350 XXXXXXXXXXXXXXXNNFEKRKAIVEQ------AKQGNTIKKKK 463
F K+KA E G++I+K K
Sbjct: 376 RMKLEEKRRMLEEESVAFAKKKATCELFPNQSFLASGSSIRKDK 419
>sp|Q5PQK1|SEP10_RAT Septin-10
Length = 456
Score = 105 bits (261), Expect = 9e-23
Identities = 55/115 (47%), Positives = 75/115 (65%), Gaps = 4/115 (3%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSD----NENM 169
G VQ++NE HCDF++LR+ML+ TNM+DLRE+TH+ HYE YR+ +L EMGF D N+ +
Sbjct: 260 GIVQVENENHCDFVKLREMLICTNMEDLREQTHMRHYELYRRCKLQEMGFIDIGPENKPL 319
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKK 334
SL ++QMF RVKEKE LKE+++EL +KFE LK+
Sbjct: 320 SLQETYEAKRHEFCGERQRKEEQMKQMFVQRVKEKEAILKEAERELQAKFEHLKR 374
>sp|Q8CHH9|SEPT8_MOUSE Septin-8
Length = 429
Score = 104 bits (260), Expect = 1e-22
Identities = 59/146 (40%), Positives = 79/146 (54%), Gaps = 4/146 (2%)
Frame = +2
Query: 2 GTVQIDNEVHCDFIRLRDMLLRTNMDDLRERTHLVHYETYRKHRLIEMGFSDNEN----M 169
G VQ++NE HCDF++LR+ML+R NM+DLRE+TH HYE YR+ +L EMGF D++
Sbjct: 261 GVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPF 320
Query: 170 SLXXXXXXXXXXXXXXXXXXXXXIRQMFFLRVKEKENQLKESDKELLSKFETLKKSNAXX 349
SL +RQMF +VKE E +LKE ++EL KFE LK+ +
Sbjct: 321 SLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRIHQEE 380
Query: 350 XXXXXXXXXXXXXXXNNFEKRKAIVE 427
N F RKA +E
Sbjct: 381 KRKVEEKRRELEEETNAFNCRKAAME 406
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,351,454
Number of Sequences: 369166
Number of extensions: 713429
Number of successful extensions: 2146
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2033
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2125
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3783975580
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)