DrC_00096
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00096 (1080 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q21988|AMX1_CAEEL Amine oxidase family member 1 90 1e-17 sp|O60341|LSD1_HUMAN Lysine-specific histone demethylase 1 ... 73 2e-12 sp|Q6ZQ88|LSD1_MOUSE Lysine-specific histone demethylase 1 ... 72 3e-12 sp|Q9XWP6|SPR5_CAEEL Suppressor of presenilin 5 (P110b homo... 65 4e-10 sp|P58028|AOFB_CAVPO Amine oxidase [flavin-containing] B (M... 46 2e-04 sp|Q7YRB7|AOFB_CANFA Amine oxidase [flavin-containing] B (M... 45 4e-04 sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B (M... 45 5e-04 sp|Q5RE98|AOFB_PONPY Amine oxidase [flavin-containing] B (M... 45 5e-04 sp|P56560|AOFB_BOVIN Amine oxidase [flavin-containing] B (M... 44 0.001 sp|Q8BW75|AOFB_MOUSE Amine oxidase [flavin-containing] B (M... 43 0.002
>sp|Q21988|AMX1_CAEEL Amine oxidase family member 1 Length = 783 Score = 90.1 bits (222), Expect = 1e-17 Identities = 75/298 (25%), Positives = 131/298 (43%), Gaps = 15/298 (5%) Frame = +1 Query: 16 EDQRIEFIRNHPASFFESIKYPVYLGTS-PYLNVYDEYSLDTVGISPIAERVNFDL---G 183 E +IE +R F +P L + Y + D Y T G+ + + G Sbjct: 129 ESPKIERVREDSEWCFNEFGHPPLLQNNISYDLLVDHYVTRTTGMDATCQEKAALIDNGG 188 Query: 184 DPCKDFMTVFNPFSKETNTQTAAGAADPTCMDKWEYEFFPTFSSGNLRSVFLGLRNLMLL 363 +D + N F T A P M+ E FP F+ + +L +RN ++ Sbjct: 189 IEFRDTRRIMNMFYVPF-TDVIANIVHPEFMETDEKFAFPKFADDPISIYYLQVRNTIIA 247 Query: 364 LWSANPKRTVNVNLVAKCVSLRGLARVALLINSVPDLIKIYSGFGYVNFGFPDAPVNIFE 543 +W +P + V ++ + +RG AR+ + + + +++ + G VN+G D ++ Sbjct: 248 MWLKHPFVELTVKMIEPQIIVRGHARIFFIEHLIHPILEFLTIKGVVNYGAFDFRIDPL- 306 Query: 544 ENMKKDVIVVGAGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRI----SLKMKAFECF 711 M+ + ++GAG+SG+S ARHL LG + + EA D G R+ SL + + Sbjct: 307 NGMRPKIAIIGAGISGISTARHLKHLGIDAVLFEAKDRF---GGRMMDDQSLGVSVGKGA 363 Query: 712 NEVFGVINNPFSVLAHQCNIETREISTDLSIFDEKGSI-------IPDDIDQFYQNLV 864 + G INNP ++L Q I+ R + + DE G + D +D Y N++ Sbjct: 364 QIIVGNINNPITLLCEQIGIKYRNSNFFCPLIDENGRCFTLERKELDDQVDLHYNNVL 421
>sp|O60341|LSD1_HUMAN Lysine-specific histone demethylase 1 (Amine oxidase flavin containing domain protein 2) (AOF2 protein) (BRAF35-HDAC complex protein BHC110) Length = 852 Score = 72.8 bits (177), Expect = 2e-12 Identities = 68/246 (27%), Positives = 114/246 (46%), Gaps = 10/246 (4%) Frame = +1 Query: 274 MDKWEYEFFPTFSSG--NLRSVFLGLRNLMLLLWSANPKRTVNVNLVAKCVSLRGLARV- 444 M E FP SG + VFL +RN L LW NPK + + A L Sbjct: 188 MTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPK--IQLTFEATLQQLEAPYNSD 245 Query: 445 ALLINSVPDLIKIYSGFGYVNFGFPDAPVNIFEENMKKDVIVVGAGLSGLSAARHLSLLG 624 +L++ V ++ + G +NFG + + K VI++G+G+SGL+AAR L G Sbjct: 246 TVLVHRVHSYLERH---GLINFGIYKRIKPLPTKKTGK-VIIIGSGVSGLAAARQLQSFG 301 Query: 625 ANVTVLEATDPLVSNGKRISLKMKAFECFN----EVFGVINNPFSVLAHQCNIETREIST 792 +VT+LEA D + G R++ K + V G+ NP +V++ Q N+E +I Sbjct: 302 MDVTLLEARDRV---GGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQ 358 Query: 793 DLSIFDEKGSIIPDDIDQFYQ---NLVYNFVAYLMGDASVITRNHSNRFEGCSLAETIQV 963 +++ G +P + D+ + N + +YL N+ + SL + ++V Sbjct: 359 KCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNN----KPVSLGQALEV 414 Query: 964 IISVAE 981 +I + E Sbjct: 415 VIQLQE 420
>sp|Q6ZQ88|LSD1_MOUSE Lysine-specific histone demethylase 1 (Amine oxidase flavin containing domain protein 2) (AOF2 protein) (BRAF35-HDAC complex protein BHC110) Length = 853 Score = 72.0 bits (175), Expect = 3e-12 Identities = 68/246 (27%), Positives = 114/246 (46%), Gaps = 10/246 (4%) Frame = +1 Query: 274 MDKWEYEFFPTFSSG--NLRSVFLGLRNLMLLLWSANPKRTVNVNLVAKCVSLRGLARV- 444 M E FP SG + VFL +RN L LW NPK + + A L Sbjct: 189 MTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPK--IQLTFEATLQQLEAPYNSD 246 Query: 445 ALLINSVPDLIKIYSGFGYVNFGFPDAPVNIFEENMKKDVIVVGAGLSGLSAARHLSLLG 624 +L++ V ++ + G +NFG + + K VI++G+G+SGL+AAR L G Sbjct: 247 TVLVHRVHSYLERH---GLINFGIYKRIKPLPIKKTGK-VIIIGSGVSGLAAARQLQSFG 302 Query: 625 ANVTVLEATDPLVSNGKRISLKMKAFECFN----EVFGVINNPFSVLAHQCNIETREIST 792 +VT+LEA D + G R++ K + V G+ NP +V++ Q N+E +I Sbjct: 303 MDVTLLEARDRV---GGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQ 359 Query: 793 DLSIFDEKGSIIPDDIDQFYQ---NLVYNFVAYLMGDASVITRNHSNRFEGCSLAETIQV 963 +++ G +P + D+ + N + +YL N+ + SL + ++V Sbjct: 360 KCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNN----KPVSLGQALEV 415 Query: 964 IISVAE 981 +I + E Sbjct: 416 VIQLQE 421
>sp|Q9XWP6|SPR5_CAEEL Suppressor of presenilin 5 (P110b homolog) Length = 770 Score = 64.7 bits (156), Expect = 4e-10 Identities = 67/223 (30%), Positives = 98/223 (43%), Gaps = 14/223 (6%) Frame = +1 Query: 223 SKETNTQTAAGAADPTCMDK---WEYEFFPT-FSSGNLRSVFLGLRNLMLLLWSANPKRT 390 S + N AA +A D+ E FFP + VFL LRN L W NP + Sbjct: 22 SIDDNALAAAASAARLPFDRPTDHELAFFPELWEHKTAVEVFLLLRNSTLATWQYNPLK- 80 Query: 391 VNVNLVAKCVSLRGLARVALLINSVPDLIK----IYSGFGYVNFG--FPDAPVNIFEENM 552 +C +L V NS DLI+ S G +NFG ++ F Sbjct: 81 -------ECTALDVRNNVFPPFNSDLDLIQNIVHYLSRHGLINFGRYVRSTKISRFLVRD 133 Query: 553 KKDVIVVGAGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISLKMKAFECF----NEV 720 ++ VIV+GAG +G+SAA L G +V VLEA + + G+ S K K+ E + + Sbjct: 134 RRSVIVIGAGAAGISAATQLESFGFDVIVLEARNCI--GGRIHSFKSKSGEIMETGGDTL 191 Query: 721 FGVINNPFSVLAHQCNIETREISTDLSIFDEKGSIIPDDIDQF 849 + ++P + L HQ N E + S+F E + + I F Sbjct: 192 RKIEDSPMATLLHQVNFEEHGVFDFTSVFVEGRPLNEEKIHLF 234
>sp|P58028|AOFB_CAVPO Amine oxidase [flavin-containing] B (Monoamine oxidase type B) (MAO-B) Length = 520 Score = 45.8 bits (107), Expect = 2e-04 Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 4/99 (4%) Frame = +1 Query: 547 NMKKDVIVVGAGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISLK---MKAFECFNE 717 N K DV+VVG G+SGL+AA+ L G NV VLEA D + G+ +L+ +K + Sbjct: 2 NSKCDVVVVGGGISGLAAAKLLHDSGLNVVVLEARDCV--GGRTYTLRNQNVKYVDLGGA 59 Query: 718 VFGVINNPFSVLAHQCNIETREIS-TDLSIFDEKGSIIP 831 G N LA + +ET ++ + I KG P Sbjct: 60 YVGPTQNRILRLAKELGLETYRVNDVERQIHHVKGKSYP 98
>sp|Q7YRB7|AOFB_CANFA Amine oxidase [flavin-containing] B (Monoamine oxidase type B) (MAO-B) Length = 520 Score = 45.1 bits (105), Expect = 4e-04 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 2/95 (2%) Frame = +1 Query: 553 KKDVIVVGAGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRI-SLKMKAFECFNEVFGV 729 K DV+VVG G+SG++AA+ L G NV VLEA D + I + K+K + G Sbjct: 4 KCDVVVVGGGISGMAAAKLLHDFGLNVVVLEARDRVGGRTYTIRNQKVKYLDLGGSYVGP 63 Query: 730 INNPFSVLAHQCNIETREIS-TDLSIFDEKGSIIP 831 N LA + +ET +++ + I KG P Sbjct: 64 TQNCILRLAKELGLETYKVNEVERLIHHVKGKSYP 98
>sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B (Monoamine oxidase type B) (MAO-B) Length = 520 Score = 44.7 bits (104), Expect = 5e-04 Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 4/97 (4%) Frame = +1 Query: 553 KKDVIVVGAGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISL---KMKAFECFNEVF 723 K DV+VVG G+SG++AA+ L G NV VLEA D + G+ +L K+K + Sbjct: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV--GGRTYTLRNQKVKYVDLGGSYV 61 Query: 724 GVINNPFSVLAHQCNIETREIS-TDLSIFDEKGSIIP 831 G N LA + +ET +++ + I KG P Sbjct: 62 GPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYP 98
>sp|Q5RE98|AOFB_PONPY Amine oxidase [flavin-containing] B (Monoamine oxidase type B) (MAO-B) Length = 520 Score = 44.7 bits (104), Expect = 5e-04 Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 4/97 (4%) Frame = +1 Query: 553 KKDVIVVGAGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISL---KMKAFECFNEVF 723 K DV+VVG G+SG++AA+ L G NV VLEA D + G+ +L K+K + Sbjct: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV--GGRTYTLRNQKVKYVDLGGSYV 61 Query: 724 GVINNPFSVLAHQCNIETREIS-TDLSIFDEKGSIIP 831 G N LA + +ET +++ + I KG P Sbjct: 62 GPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYP 98
>sp|P56560|AOFB_BOVIN Amine oxidase [flavin-containing] B (Monoamine oxidase type B) (MAO-B) Length = 520 Score = 43.5 bits (101), Expect = 0.001 Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 4/97 (4%) Frame = +1 Query: 553 KKDVIVVGAGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISL---KMKAFECFNEVF 723 K DV+VVG G+SG++AA+ L G NV VLEA D + G+ +L K+K + Sbjct: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRV--GGRTYTLRNQKVKYVDLGGSYV 61 Query: 724 GVINNPFSVLAHQCNIETREIS-TDLSIFDEKGSIIP 831 G N L+ + +ET +++ + I KG P Sbjct: 62 GPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYP 98
>sp|Q8BW75|AOFB_MOUSE Amine oxidase [flavin-containing] B (Monoamine oxidase type B) (MAO-B) Length = 520 Score = 42.7 bits (99), Expect = 0.002 Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 1/80 (1%) Frame = +1 Query: 553 KKDVIVVGAGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISLK-MKAFECFNEVFGV 729 K DVIVVG G+SG++AA+ L G +V VLEA D + I K +K + G Sbjct: 4 KSDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSYVGP 63 Query: 730 INNPFSVLAHQCNIETREIS 789 N LA + +ET +++ Sbjct: 64 TQNRILRLAKELGLETYKVN 83
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 132,648,275
Number of Sequences: 369166
Number of extensions: 2953880
Number of successful extensions: 10388
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9801
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10380
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 11773171020
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
