Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_L02
(504 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60341|LSD1_HUMAN Lysine-specific histone demethylase 1 ... 52 8e-07
sp|Q6ZQ88|LSD1_MOUSE Lysine-specific histone demethylase 1 ... 52 8e-07
sp|Q21988|AMX1_CAEEL Amine oxidase family member 1 48 2e-05
sp|Q9XWP6|SPR5_CAEEL Suppressor of presenilin 5 (P110b homo... 37 0.020
sp|Q7YRB7|AOFB_CANFA Amine oxidase [flavin-containing] B (M... 34 0.23
sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B (M... 33 0.29
sp|Q5RE98|AOFB_PONPY Amine oxidase [flavin-containing] B (M... 33 0.29
sp|P58028|AOFB_CAVPO Amine oxidase [flavin-containing] B (M... 33 0.50
sp|P56560|AOFB_BOVIN Amine oxidase [flavin-containing] B (M... 32 0.66
sp|P57876|OTC_PASMU Ornithine carbamoyltransferase (OTCase) 32 1.1
>sp|O60341|LSD1_HUMAN Lysine-specific histone demethylase 1 (Amine oxidase flavin
containing domain protein 2) (AOF2 protein) (BRAF35-HDAC
complex protein BHC110)
Length = 852
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/142 (27%), Positives = 70/142 (49%), Gaps = 7/142 (4%)
Frame = +1
Query: 1 AGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISLKMKAFECFN----EVFGVINNPF 168
+G+SGL+AAR L G +VT+LEA D + G R++ K + V G+ NP
Sbjct: 286 SGVSGLAAARQLQSFGMDVTLLEARDRV---GGRVATFRKGNYVADLGAMVVTGLGGNPM 342
Query: 169 SVLAHQCNIETREISTDLSIFDEKGSIIPDDIDQFYQ---NLVYNFVAYLMGDASVITRN 339
+V++ Q N+E +I +++ G +P + D+ + N + +YL N
Sbjct: 343 AVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLN 402
Query: 340 HSNRFEGCSLAETIQVIISVAE 405
+ + SL + ++V+I + E
Sbjct: 403 N----KPVSLGQALEVVIQLQE 420
>sp|Q6ZQ88|LSD1_MOUSE Lysine-specific histone demethylase 1 (Amine oxidase flavin
containing domain protein 2) (AOF2 protein) (BRAF35-HDAC
complex protein BHC110)
Length = 853
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/142 (27%), Positives = 70/142 (49%), Gaps = 7/142 (4%)
Frame = +1
Query: 1 AGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISLKMKAFECFN----EVFGVINNPF 168
+G+SGL+AAR L G +VT+LEA D + G R++ K + V G+ NP
Sbjct: 287 SGVSGLAAARQLQSFGMDVTLLEARDRV---GGRVATFRKGNYVADLGAMVVTGLGGNPM 343
Query: 169 SVLAHQCNIETREISTDLSIFDEKGSIIPDDIDQFYQ---NLVYNFVAYLMGDASVITRN 339
+V++ Q N+E +I +++ G +P + D+ + N + +YL N
Sbjct: 344 AVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLN 403
Query: 340 HSNRFEGCSLAETIQVIISVAE 405
+ + SL + ++V+I + E
Sbjct: 404 N----KPVSLGQALEVVIQLQE 421
>sp|Q21988|AMX1_CAEEL Amine oxidase family member 1
Length = 783
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Frame = +1
Query: 1 AGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRI----SLKMKAFECFNEVFGVINNPF 168
AG+SG+S ARHL LG + + EA D G R+ SL + + + G INNP
Sbjct: 318 AGISGISTARHLKHLGIDAVLFEAKDRF---GGRMMDDQSLGVSVGKGAQIIVGNINNPI 374
Query: 169 SVLAHQCNIETREISTDLSIFDEKGSI-------IPDDIDQFYQNLV 288
++L Q I+ R + + DE G + D +D Y N++
Sbjct: 375 TLLCEQIGIKYRNSNFFCPLIDENGRCFTLERKELDDQVDLHYNNVL 421
>sp|Q9XWP6|SPR5_CAEEL Suppressor of presenilin 5 (P110b homolog)
Length = 770
Score = 37.4 bits (85), Expect = 0.020
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Frame = +1
Query: 1 AGLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISLKMKAFECF----NEVFGVINNPF 168
AG +G+SAA L G +V VLEA + + G+ S K K+ E + + + ++P
Sbjct: 142 AGAAGISAATQLESFGFDVIVLEARNCI--GGRIHSFKSKSGEIMETGGDTLRKIEDSPM 199
Query: 169 SVLAHQCNIETREISTDLSIFDEKGSIIPDDIDQF 273
+ L HQ N E + S+F E + + I F
Sbjct: 200 ATLLHQVNFEEHGVFDFTSVFVEGRPLNEEKIHLF 234
>sp|Q7YRB7|AOFB_CANFA Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 33.9 bits (76), Expect = 0.23
Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Frame = +1
Query: 4 GLSGLSAARHLSLLGANVTVLEATDPLVSNGKRI-SLKMKAFECFNEVFGVINNPFSVLA 180
G+SG++AA+ L G NV VLEA D + I + K+K + G N LA
Sbjct: 13 GISGMAAAKLLHDFGLNVVVLEARDRVGGRTYTIRNQKVKYLDLGGSYVGPTQNCILRLA 72
Query: 181 HQCNIETREIS-TDLSIFDEKGSIIP 255
+ +ET +++ + I KG P
Sbjct: 73 KELGLETYKVNEVERLIHHVKGKSYP 98
>sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 33.5 bits (75), Expect = 0.29
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Frame = +1
Query: 4 GLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISL---KMKAFECFNEVFGVINNPFSV 174
G+SG++AA+ L G NV VLEA D + G+ +L K+K + G N
Sbjct: 13 GISGMAAAKLLHDSGLNVVVLEARDRV--GGRTYTLRNQKVKYVDLGGSYVGPTQNRILR 70
Query: 175 LAHQCNIETREIS-TDLSIFDEKGSIIP 255
LA + +ET +++ + I KG P
Sbjct: 71 LAKELGLETYKVNEVERLIHHVKGKSYP 98
>sp|Q5RE98|AOFB_PONPY Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 33.5 bits (75), Expect = 0.29
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Frame = +1
Query: 4 GLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISL---KMKAFECFNEVFGVINNPFSV 174
G+SG++AA+ L G NV VLEA D + G+ +L K+K + G N
Sbjct: 13 GISGMAAAKLLHDSGLNVVVLEARDRV--GGRTYTLRNQKVKYVDLGGSYVGPTQNRILR 70
Query: 175 LAHQCNIETREIS-TDLSIFDEKGSIIP 255
LA + +ET +++ + I KG P
Sbjct: 71 LAKELGLETYKVNEVERLIHHVKGKSYP 98
>sp|P58028|AOFB_CAVPO Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 32.7 bits (73), Expect = 0.50
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Frame = +1
Query: 4 GLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISLK---MKAFECFNEVFGVINNPFSV 174
G+SGL+AA+ L G NV VLEA D + G+ +L+ +K + G N
Sbjct: 13 GISGLAAAKLLHDSGLNVVVLEARDCV--GGRTYTLRNQNVKYVDLGGAYVGPTQNRILR 70
Query: 175 LAHQCNIETREIS-TDLSIFDEKGSIIP 255
LA + +ET ++ + I KG P
Sbjct: 71 LAKELGLETYRVNDVERQIHHVKGKSYP 98
>sp|P56560|AOFB_BOVIN Amine oxidase [flavin-containing] B (Monoamine oxidase type B)
(MAO-B)
Length = 520
Score = 32.3 bits (72), Expect = 0.66
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Frame = +1
Query: 4 GLSGLSAARHLSLLGANVTVLEATDPLVSNGKRISL---KMKAFECFNEVFGVINNPFSV 174
G+SG++AA+ L G NV VLEA D + G+ +L K+K + G N
Sbjct: 13 GISGMAAAKLLHDSGLNVIVLEARDRV--GGRTYTLRNQKVKYVDLGGSYVGPTQNHILR 70
Query: 175 LAHQCNIETREIS-TDLSIFDEKGSIIP 255
L+ + +ET +++ + I KG P
Sbjct: 71 LSKELGLETYKVNEVERLIHHTKGKSYP 98
>sp|P57876|OTC_PASMU Ornithine carbamoyltransferase (OTCase)
Length = 334
Score = 31.6 bits (70), Expect = 1.1
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = +3
Query: 306 PDGGRLGHHKEPLQSIRGVLARRNYSGYNFRGRANQLIEFVLRGNGSSV 452
P G ++GH KE ++ VL R Y G +RG +L+E + + +G V
Sbjct: 80 PSGSQIGH-KESMKDTARVLGRM-YDGIQYRGYGQELVEILAQYSGVPV 126
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,838,154
Number of Sequences: 369166
Number of extensions: 1319127
Number of successful extensions: 4103
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4018
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4100
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3218280650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)