DrC_00044
- Cluster detail
- GO Category :
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00044 (1180 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9V3A4|CSUP_DROME Catecholamines up protein 251 2e-66 sp|Q92504|KE4_HUMAN Zinc transporter SLC39A7 (Solute carrie... 233 1e-60 sp|Q31125|KE4_MOUSE Zinc transporter SLC39A7 (Solute carrie... 231 2e-60 sp|Q9XTQ7|KE4L_CAEEL Hypothetical Ke4-like protein H13N06.5... 223 1e-57 sp|Q9XUC4|YGJK_CAEEL Hypothetical protein T28F3.3 in chromo... 204 3e-52 sp|Q9PUB8|KE4_BRARE Zinc transporter Slc39a7 (Solute carrie... 154 6e-37 sp|Q9VAF0|Y816_DROME Hypothetical protein CG7816 135 2e-31 sp|P40544|YIC3_YEAST Hypothetical 37.4 kDa protein in IRR1-... 117 6e-26 sp|Q9VSL7|FOI_DROME Zinc transporter foi precursor (Fear-of... 117 6e-26 sp|Q5R9M9|S39A6_PONPY Zinc transporter SLC39A6 precursor (S... 100 8e-21
>sp|Q9V3A4|CSUP_DROME Catecholamines up protein Length = 449 Score = 251 bits (642), Expect = 2e-66 Identities = 144/344 (41%), Positives = 198/344 (57%), Gaps = 7/344 (2%) Frame = +3 Query: 15 LWLYSLSATILVSAAPLLVIFLIP--DLKNHRVXXXXXXXXXXXXXXXXXXXXXIPHSID 188 +WL+S+ +T+L+SAAP +++++IP + + + IPH+ Sbjct: 131 IWLHSIGSTLLISAAPFVLLYIIPLDNSEAMKPRLKVLLAFASGGLLGDAFLHLIPHATH 190 Query: 189 PHDHQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXALHDHSKNMIVGLWVVAGIMSFLIVE 368 PH H H HS +M +GLWV+ GI++FL VE Sbjct: 191 PHSHGEHGHDHGHDHHHHHDGEEHE-----------HGHSHDMSIGLWVLGGIIAFLSVE 239 Query: 369 KFVRLVKGDXXXXXXXXXXL----IITEPPFSNKKQSSKGENTNSEMEVRSRXXXXXXXX 536 K VR++KG + + S+K+ S G+ +++S+ Sbjct: 240 KLVRILKGGHGGHGHSHGAPKPKPVPAKKKSSDKEDSGDGDKPAKPAKIKSKKPE----- 294 Query: 537 XXXXXXALAVDQVQNIKVSGYLNLVADFAHNFTDGLAIGASFLVNKNVGIVTTITILFHE 716 + +++SGYLNL ADFAHNFTDGLAIGAS+L ++GIVTTITIL HE Sbjct: 295 ---------AEPEGEVEISGYLNLAADFAHNFTDGLAIGASYLAGNSIGIVTTITILLHE 345 Query: 717 VPHEIGDYAILIQSGCSRRKAILLQLVTAVGAMLGTVLSLLAQDIGT-SSTWILPFTAGG 893 VPHEIGD+AILI+SGCSRRKA+LLQLVTA+GA+ GT L+LL G S+ W+LPFTAGG Sbjct: 346 VPHEIGDFAILIKSGCSRRKAMLLQLVTALGALAGTALALLGAGGGDGSAPWVLPFTAGG 405 Query: 894 FIYISTVSVLPELLKNHSTFSQSISEIIAMVTGVGMMVAIAYFE 1025 FIYI+TVSVLPELL+ + QS+ EI A++TGV +M+ IA FE Sbjct: 406 FIYIATVSVLPELLEESTKLKQSLKEIFALLTGVALMIVIAKFE 449
>sp|Q92504|KE4_HUMAN Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4) Length = 469 Score = 233 bits (593), Expect = 1e-60 Identities = 146/360 (40%), Positives = 198/360 (55%), Gaps = 23/360 (6%) Frame = +3 Query: 15 LWLYSLSATILVSAAPLLVIFLIPDLKN---HRVXXXXXXXXXXXXXXXXXXXXXIPHSI 185 LW Y+L AT+L+SAAP V+FLIP N HR IPH++ Sbjct: 134 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 193 Query: 186 DPHDHQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXALHDHSKN---MIVGLWVVAGIMSF 356 +PH H H HS + VGLWV++GI++F Sbjct: 194 EPHSHHTLEQPGHG-----------------------HSHSGQGPILSVGLWVLSGIVAF 230 Query: 357 LIVEKFVRLVKGDXXXXXXXXXXLIITEPPFSNKKQ--SSKGENTNSEME-----VRSRX 515 L+VEKFVR VKG T + +Q S+K + ++ E E V+ R Sbjct: 231 LVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRR 290 Query: 516 XXXXXXXXXXXXXALAVDQVQ--NIKVSGYLNLVADFAHNFTDGLAIGASFLVNKNVGIV 689 A ++ + +++VSGYLNL AD AHNFTDGLAIGASF + +GI+ Sbjct: 291 GGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGIL 350 Query: 690 TTITILFHEVPHEIGDYAILIQSGCSRRKAILLQLVTAVGAMLGTVLSLLAQD------- 848 TT+T+L HEVPHE+GD+AIL+QSGCS+++A+ LQL+TAVGA+ GT +LL + Sbjct: 351 TTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEI 410 Query: 849 -IGTSSTWILPFTAGGFIYISTVSVLPELLKNHSTFSQSISEIIAMVTGVGMMVAIAYFE 1025 G W+LPFTAGGFIY++TVSVLPELL+ S QS+ E++ ++ GV MMV IA+ E Sbjct: 411 AGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPL-QSLLEVLGLLGGVIMMVLIAHLE 469
>sp|Q31125|KE4_MOUSE Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4) Length = 476 Score = 231 bits (590), Expect = 2e-60 Identities = 144/359 (40%), Positives = 196/359 (54%), Gaps = 22/359 (6%) Frame = +3 Query: 15 LWLYSLSATILVSAAPLLVIFLIPDLKN---HRVXXXXXXXXXXXXXXXXXXXXXIPHSI 185 LW Y+L AT+L+SAAP V+FLIP N HR IPH++ Sbjct: 142 LWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 201 Query: 186 DPHDHQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXALHDHSKN---MIVGLWVVAGIMSF 356 +PH H H HS + VGLWV++GI++F Sbjct: 202 EPHSHHAPEQPGHG-----------------------HSHSGQGPILSVGLWVLSGIVAF 238 Query: 357 LIVEKFVRLVKGDXXXXXXXXXXLIITEP-PFSNKKQSSKGENTNSEME-----VRSRXX 518 L+VEKFVR VKG + ++ + S E ++E E +R R Sbjct: 239 LVVEKFVRHVKGGHGHSHGHGDRHAHGDSHTHGDRHECSSKEKPSTEEEKEVGGLRKRRG 298 Query: 519 XXXXXXXXXXXXALAVDQV--QNIKVSGYLNLVADFAHNFTDGLAIGASFLVNKNVGIVT 692 ++ +++VSGYLNL AD AHNFTDGLAIGASF + +GI+T Sbjct: 299 GNTGPRDGPVKPQSPEEEKAGSDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILT 358 Query: 693 TITILFHEVPHEIGDYAILIQSGCSRRKAILLQLVTAVGAMLGTVLSLLAQ------DI- 851 T+T+L HEVPHE+GD+AIL+QSGCS+++A+ LQLVTA+GA+ GT +LL + D+ Sbjct: 359 TMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLVTAIGALAGTACALLTEGGAVDSDVA 418 Query: 852 -GTSSTWILPFTAGGFIYISTVSVLPELLKNHSTFSQSISEIIAMVTGVGMMVAIAYFE 1025 G W+LPFTAGGFIY++TVSVLPELL+ S QS+ E++ ++ GV MMV IA+ E Sbjct: 419 GGAGPGWVLPFTAGGFIYVATVSVLPELLREASPL-QSLLEVLGLLGGVAMMVLIAHLE 476
>sp|Q9XTQ7|KE4L_CAEEL Hypothetical Ke4-like protein H13N06.5 in chromosome X Length = 515 Score = 223 bits (567), Expect = 1e-57 Identities = 139/351 (39%), Positives = 192/351 (54%), Gaps = 12/351 (3%) Frame = +3 Query: 9 TRLWLYSLSATILVSAAPLLVIFLIPDLKNHRVXXXXXXXXXXXXXXXXXXXXX---IPH 179 TRLW+Y++SAT+L+SAAP ++ IP N IPH Sbjct: 208 TRLWVYAISATLLISAAPCFILMFIPIQANTSESGPLLKVLLAFGSGGLLGDAFLHLIPH 267 Query: 180 SI---DPHDHQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXALHDH-SKNMIVGLWVVAGI 347 + D H H H H + +M VG WV+ GI Sbjct: 268 ATPAGDGHGHSHSHGHSHGGGG--------------------HSHGAHDMSVGGWVLGGI 307 Query: 348 MSFLIVEKFVRLVKGDXXXXXXXXXXLIITEPPFSNKKQSSKGENTNSEMEVRSRXXXXX 527 ++FL VEK VR+++G+ +K+ +K +++ ++ + Sbjct: 308 IAFLTVEKLVRILRGEDGHGHSHGHS-------HGGEKKETKEKDSKDKVAKKEEKPEKD 360 Query: 528 XXXXXXXXXALAVDQVQNIKVSGYLNLVADFAHNFTDGLAIGASFLVNKNVGIVTTITIL 707 Q+IKV+ YLNL ADF HNFTDGLAIGASF+ VGIVT IT+L Sbjct: 361 E---------------QSIKVTAYLNLAADFTHNFTDGLAIGASFIAGTTVGIVTMITVL 405 Query: 708 FHEVPHEIGDYAILIQSGCSRRKAILLQLVTAVGAMLGTVLSLLAQDI-----GTSSTWI 872 HEVPHEIGD+AILIQSG S++KA+L+QLVTA+GA+ G V+SL + D +S+W+ Sbjct: 406 VHEVPHEIGDFAILIQSGYSKKKAMLIQLVTALGALSGCVISLFSADADALADAAASSWV 465 Query: 873 LPFTAGGFIYISTVSVLPELLKNHSTFSQSISEIIAMVTGVGMMVAIAYFE 1025 LPFTAGGFIYI+TVSV+PELL+N S+F Q++ EI A++TG+ +M IA +E Sbjct: 466 LPFTAGGFIYIATVSVIPELLEN-SSFFQTVKEIFAILTGIFLMYLIAIYE 515
Score = 32.7 bits (73), Expect = 2.1
Identities = 16/52 (30%), Positives = 25/52 (48%)
Frame = -2
Query: 270 HGCARVYDCDHVHDHAYVHGNYSDDHEDQ*NEESNVEMHLPIDHRQQRQEEY 115
HG A +D H HDH + H ++ H++ EE + H DH E++
Sbjct: 131 HGHAHDHDHGHAHDHGHAHDHHGHSHDE---EEDHHHGHAH-DHHGHSHEDH 178
>sp|Q9XUC4|YGJK_CAEEL Hypothetical protein T28F3.3 in chromosome IV Length = 393 Score = 204 bits (520), Expect = 3e-52 Identities = 126/351 (35%), Positives = 182/351 (51%), Gaps = 13/351 (3%) Frame = +3 Query: 12 RLWLYSLSATILVSAAPLLVIFLIPDLKNHRVXXXXXXXXXXXXXXXXXXXXXIPHSIDP 191 ++W++SLSA + +S AP ++F IP + IPHS+ P Sbjct: 82 KVWVFSLSAVVGISLAPCTLLFFIPAQHANGPFLKILLAFGAGGLLGDALLHIIPHSLSP 141 Query: 192 HDHQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXALHDHSKNMIVGLWVVAGIMSFLIVEK 371 HDH HDHS + VG +V+AGI+ F++VE+ Sbjct: 142 HDHSHDHHDHNHSHKEHDHS---------------HDHSNQLRVGTFVIAGILVFMMVEQ 186 Query: 372 FVRLVKGDXXXXXXXXXXLIITEPPFSNKKQSSKGENTNSEMEVRSRXXXXXXXXXXXXX 551 VR++KG ++ E N+ E ++E Sbjct: 187 LVRIIKGGHCHSHENGH-IVADEHRHLNEHDHEHSEEKKQQVE----------------- 228 Query: 552 XALAVDQVQNIKVSGYLNLVADFAHNFTDGLAIGASFLVNKNVGIVTTITILFHEVPHEI 731 ++++K S YLNLVADF HN TDGLAIGASF +G +TT+T+L HE+PHE+ Sbjct: 229 ------GLKDVKASAYLNLVADFVHNVTDGLAIGASFSAGNTLGWITTLTVLLHELPHEV 282 Query: 732 GDYAILIQSGCSRRKAILLQLVTAVGAMLGTVLSLLAQDIGT-----SSTWILPFTAGGF 896 GD+AIL+QSG S+ +AI LQ VTA+GA+ G V SLL + G+ ++ I+PFTAGGF Sbjct: 283 GDFAILVQSGFSKYQAIRLQAVTALGAITGCVFSLLVSNPGSLNNDADTSAIMPFTAGGF 342 Query: 897 IYISTVSVLPELLK--NHSTFS------QSISEIIAMVTGVGMMVAIAYFE 1025 IYI+TVSV+PELL+ +H+ S QS+ ++A+ GVGMM ++ E Sbjct: 343 IYIATVSVVPELLESGDHNNLSKVAKMAQSLVHVLAICMGVGMMYIVSLVE 393
>sp|Q9PUB8|KE4_BRARE Zinc transporter Slc39a7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4) Length = 352 Score = 154 bits (388), Expect = 6e-37 Identities = 98/249 (39%), Positives = 127/249 (51%), Gaps = 3/249 (1%) Frame = +3 Query: 15 LWLYSLSATILVSAAPLLVIFLIPDLKN---HRVXXXXXXXXXXXXXXXXXXXXXIPHSI 185 LW+ ++ AT+L+SAAP L++FLIP N H+ IPH++ Sbjct: 124 LWMQAIGATLLISAAPFLILFLIPVQSNTDQHQNLLKVLLSFASGGLLGDAFLHLIPHAL 183 Query: 186 DPHDHQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXALHDHSKNMIVGLWVVAGIMSFLIV 365 +PH H A H H M VGLWV+ GI++FL+V Sbjct: 184 EPHSHHSQPHSEESHGQSHGEESHGHSHG------AAHGHM--MSVGLWVLGGIVAFLVV 235 Query: 366 EKFVRLVKGDXXXXXXXXXXLIITEPPFSNKKQSSKGENTNSEMEVRSRXXXXXXXXXXX 545 EKFVRL+KG ++ S+++ KG+ + +V S+ Sbjct: 236 EKFVRLLKGGHSHSHSHSPSAPKSKD--SDEEDDKKGQKKGEKDKVVSQQKPTKK----- 288 Query: 546 XXXALAVDQVQNIKVSGYLNLVADFAHNFTDGLAIGASFLVNKNVGIVTTITILFHEVPH 725 V+ +IKVSGYLNL ADF HNFTDGLAIGASFLV VG VTTITIL HEVPH Sbjct: 289 -----TVETSSDIKVSGYLNLAADFTHNFTDGLAIGASFLVGPAVGAVTTITILLHEVPH 343 Query: 726 EIGDYAILI 752 EIGD+AIL+ Sbjct: 344 EIGDFAILV 352
>sp|Q9VAF0|Y816_DROME Hypothetical protein CG7816 Length = 355 Score = 135 bits (341), Expect = 2e-31 Identities = 84/234 (35%), Positives = 127/234 (54%), Gaps = 4/234 (1%) Frame = +3 Query: 324 GLWVVAGIMSFLIVEKFVRLVKGDXXXXXXXXXXLIITEPPFSNKKQSSKGENTNSEMEV 503 GLWV++GI+ F IVEK I + Q +GE + S Sbjct: 117 GLWVLSGILIFTIVEKIFSGYASADEENPQPKCVEIANCLLRRHGGQLPEGETSESCGGA 176 Query: 504 RSRXXXXXXXXXXXXXXALAVDQVQNIKVSGYLNLVADFAHNFTDGLAIGASFLVNKNVG 683 + Q KV+GYLNL+A+ NFT GLA+ SFLV+ G Sbjct: 177 CDIEDVGKVCFLREQEQKSKERKEQPKKVAGYLNLLANSIDNFTHGLAVAGSFLVSFRHG 236 Query: 684 IVTTITILFHEVPHEIGDYAILIQSGCSRRKAILLQLVTAVGAMLGTVLSLLAQDIGTS- 860 I+ T IL HE+PHE+GD+AIL++SG SR A QL+TA +LG ++++ + ++ Sbjct: 237 ILATFAILLHEIPHEVGDFAILLRSGFSRWDAARAQLLTAGAGLLGALVAIGGSGVTSAM 296 Query: 861 ---STWILPFTAGGFIYISTVSVLPELLKNHSTFSQSISEIIAMVTGVGMMVAI 1013 ++WI+PFTAGGF++I+ V+VLP+LLK +SI +++A+V G+ +M + Sbjct: 297 EARTSWIMPFTAGGFLHIALVTVLPDLLKEEER-KESIKQLLALVFGIALMAVM 349
>sp|P40544|YIC3_YEAST Hypothetical 37.4 kDa protein in IRR1-TIM44 intergenic region Length = 346 Score = 117 bits (293), Expect = 6e-26 Identities = 59/135 (43%), Positives = 89/135 (65%), Gaps = 11/135 (8%) Frame = +3 Query: 588 VSGYLNLVADFAHNFTDGLAIGASFLVNKNVGIVTTITILFHEVPHEIGDYAILIQSGCS 767 +S YLN+++ AH+ TDG+A+ SF + VGI+T+I + FHE+PHE+GD+AIL+ SG + Sbjct: 185 MSAYLNVISGIAHHITDGIALATSFYSSTQVGIMTSIAVTFHEIPHELGDFAILLSSGFT 244 Query: 768 RRKAILLQLVTAVGAMLGTVLSLLAQDIG-----------TSSTWILPFTAGGFIYISTV 914 +AI Q VTA GA++GT + +IG +S +LPFTAGG IYI+T Sbjct: 245 FPQAIRAQAVTAFGAVVGTSIGCWMNEIGNNSHKATSSSANASELMLPFTAGGLIYIATT 304 Query: 915 SVLPELLKNHSTFSQ 959 SV+P++L + + S+ Sbjct: 305 SVVPQILHSSAPDSK 319
>sp|Q9VSL7|FOI_DROME Zinc transporter foi precursor (Fear-of-intimacy protein) (Kastchen protein) Length = 706 Score = 117 bits (293), Expect = 6e-26 Identities = 54/150 (36%), Positives = 93/150 (62%) Frame = +3 Query: 576 QNIKVSGYLNLVADFAHNFTDGLAIGASFLVNKNVGIVTTITILFHEVPHEIGDYAILIQ 755 + + ++ ++ D HNFTDG+AIGA+F N G T++ + HE+PHE+GD+AILI+ Sbjct: 538 ETLSAVAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIK 597 Query: 756 SGCSRRKAILLQLVTAVGAMLGTVLSLLAQDIGTSSTWILPFTAGGFIYISTVSVLPELL 935 +G S + A+ L+T V + +G + + + W+ AG FIYI+ V ++PE+ Sbjct: 598 AGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYIALVDMMPEIS 657 Query: 936 KNHSTFSQSISEIIAMVTGVGMMVAIAYFE 1025 +H + Q + +I+ M++GVG+M+ IA +E Sbjct: 658 ASHKSLGQFLLQILGMLSGVGIMLLIALYE 687
>sp|Q5R9M9|S39A6_PONPY Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) Length = 743 Score = 100 bits (249), Expect = 8e-21 Identities = 52/155 (33%), Positives = 91/155 (58%), Gaps = 7/155 (4%) Frame = +3 Query: 582 IKVSGYLNLVADFAHNFTDGLAIGASFLVNKNVGIVTTITILFHEVPHEIGDYAILIQSG 761 I ++ ++ D HNF+DGLAIGA+F + G+ T++ + HE+PHE+GD+A+L+++G Sbjct: 580 IATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAG 639 Query: 762 CSRRKAILLQLVTAVGAMLGTVLSLLAQDIGTS-STWILPFTAGGFIYISTVSVLPELLK 938 + ++A+L ++A+ A LG + + S WI TAG F+Y++ V ++PE+L Sbjct: 640 MTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLH 699 Query: 939 NH------STFSQSISEIIAMVTGVGMMVAIAYFE 1025 N S + + M+ G G+M+ I+ FE Sbjct: 700 NDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFE 734
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 116,686,226
Number of Sequences: 369166
Number of extensions: 2060789
Number of successful extensions: 5223
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4894
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5153
length of database: 68,354,980
effective HSP length: 113
effective length of database: 47,479,925
effective search space used: 13246899075
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
