Planaria EST Database

DrC_00022

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00022
         (1100 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P21613|KINH_LOLPE  Kinesin heavy chain                         280   5e-75
sp|P35978|KINH_STRPU  Kinesin heavy chain                         270   7e-72
sp|P17210|KINH_DROME  Kinesin heavy chain                         268   2e-71
sp|O60282|KIF5C_HUMAN  Kinesin heavy chain isoform 5C (Kines...   265   2e-70
sp|P28738|KIF5C_MOUSE  Kinesin heavy chain isoform 5C (Kines...   263   7e-70
sp|P33175|KINN_MOUSE  Neuronal kinesin heavy chain (NKHC) (K...   254   3e-67
sp|Q12840|KINN_HUMAN  Neuronal kinesin heavy chain (NKHC) (K...   253   9e-67
sp|P33176|KINH_HUMAN  Kinesin heavy chain (Ubiquitous kinesi...   252   2e-66
sp|Q61768|KINH_MOUSE  Kinesin heavy chain (Ubiquitous kinesi...   251   3e-66
sp|P34540|KINH_CAEEL  Kinesin heavy chain (Uncoordinated pro...   131   4e-30

>sp|P21613|KINH_LOLPE Kinesin heavy chain
          Length = 967

 Score =  280 bits (716), Expect = 5e-75
 Identities = 157/311 (50%), Positives = 201/311 (64%)
 Frame = +1

Query: 1    EFEVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQL 180
            + E +M +L   + ++E +KR LE+  D L+ E +K KA EQ+ + A ++   E      
Sbjct: 635  QHEAKMASLQEAIKDSENKKRMLEDNVDSLNEEYAKLKAQEQMHLAALSEREKETSQAS- 693

Query: 181  DIKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKVV 360
            + +  L+++ +   EQ+ +Q++ LRD++ EKQ   + +KD    LS   EKL+ DY+K+ 
Sbjct: 694  ETREVLEKQMEMHREQHQKQLQSLRDEISEKQATVDNLKDDNQRLSLALEKLQADYDKLK 753

Query: 361  AEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKST 540
             E   KAAKL  +    ++REQA+QDLKGLE+TV KELQTLHNLRKLFVQDL N+VKKS 
Sbjct: 754  QEEVEKAAKLADLSLQIDRREQAKQDLKGLEETVAKELQTLHNLRKLFVQDLQNKVKKSC 813

Query: 541  RGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXX 720
                                  N  QKQKI FLE NLEQLTKVHKQLVRDN+D       
Sbjct: 814  SKTEEEDEDTGG----------NAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK 863

Query: 721  XXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAK 900
                  +T ERVK+LESALKDAKEGAMRDR+RYQHEVDRIKEAVRQ+N+ARRG+A QIAK
Sbjct: 864  LEKRLRATMERVKSLESALKDAKEGAMRDRKRYQHEVDRIKEAVRQKNLARRGHAAQIAK 923

Query: 901  PIRAGHAPSAS 933
            PIR G   S S
Sbjct: 924  PIRPGQHQSVS 934


 Score = 36.6 bits (83), Expect = 0.13
 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
 Frame = +1

Query: 25  LNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQLDIKSKLDE 204
           L++K DE   Q + +E+  +Q+  +      + +   N   Q+ + I A     K ++ E
Sbjct: 426 LDDKDDEINNQSQLIEKLKEQMMEQEDLIAQSRRDYENLQ-QDMSRIQADNESAKDEVKE 484

Query: 205 EFKRQSE---QYSQQIKELRDKLDEKQRASEEMKDKIHHL-SFQNE 330
             +   E    Y Q+ +E+ DK  E +  SEE+  K+  L S QNE
Sbjct: 485 VLQALEELAMNYDQKSQEVEDKNKENENLSEELNQKLSTLNSLQNE 530

>sp|P35978|KINH_STRPU Kinesin heavy chain
          Length = 1031

 Score =  270 bits (689), Expect = 7e-72
 Identities = 147/311 (47%), Positives = 202/311 (64%), Gaps = 3/311 (0%)
 Frame = +1

Query: 1    EFEVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEI---LA 171
            + E +M +L+  + ETE +KR LE+  D L+ E+ K +A E++ +      + E    + 
Sbjct: 628  QHEAKMKSLSENIRETEGKKRHLEDSLDMLNEEIVKLRAAEEIRLTDQEDKKREEEDKMQ 687

Query: 172  GQLDIKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYE 351
               ++++ + E+ +   + + +Q+  LR +++EK+   EE+KD    ++ Q+EKL+ DYE
Sbjct: 688  SATEMQASMSEQMESHRDAHQKQLANLRTEINEKEHQMEELKDVNQRMTLQHEKLQLDYE 747

Query: 352  KVVAEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVK 531
            K+  E   KAAKL  + +  ++REQA+QDLKGLE+TV KELQTLHNLRKLFV DL NRVK
Sbjct: 748  KLKIEEAEKAAKLRELSQQFDRREQAKQDLKGLEETVAKELQTLHNLRKLFVSDLQNRVK 807

Query: 532  KSTRGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXX 711
            K+  G +                  +  QKQKI FLE NLEQLTKVHKQLVRDN+D    
Sbjct: 808  KALEGGDRDDDSGG-----------SQAQKQKISFLENNLEQLTKVHKQLVRDNADLRCE 856

Query: 712  XXXXXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQ 891
                     +T+ERVKALE +LK+ KEGAMRDR+RYQ EVDRI+EAVRQRN A+RG++ Q
Sbjct: 857  LPKLERRLRATSERVKALEMSLKETKEGAMRDRKRYQQEVDRIREAVRQRNFAKRGSSAQ 916

Query: 892  IAKPIRAGHAP 924
            IAK IRAGH P
Sbjct: 917  IAKAIRAGHPP 927


 Score = 40.4 bits (93), Expect = 0.009
 Identities = 34/182 (18%), Positives = 84/182 (46%), Gaps = 8/182 (4%)
 Frame = +1

Query: 7   EVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQLDI 186
           E+      N+ ++ + +  +L+ Q   L  E+ +++A E + V        EIL   +  
Sbjct: 334 ELTAEEWRNRYEKEKEKNGRLKAQLLILENELQRWRAGESVPVKEQGNKNDEILKEMMKP 393

Query: 187 KSKLDEEFKRQSEQYSQQIKELRDKLDEK-------QRASEEMKDKIHHLSFQNEKLKED 345
           K       + +  ++ ++  +L ++LDEK        R +E++K ++         ++ D
Sbjct: 394 KQMTVHVSEEEKNKWEEEKVKLYEQLDEKDSEIDNQSRLTEKLKQQMLEQEELLSSMQRD 453

Query: 346 YEKVVAE-GEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSN 522
           YE + ++ G ++A      E+A E   QA +++    D   KE++  + + +   ++++ 
Sbjct: 454 YELLQSQMGRLEAENAAAKEEAKEVL-QALEEMAVNYDEKSKEVEDKNRMNETLSEEVNE 512

Query: 523 RV 528
           ++
Sbjct: 513 KM 514

>sp|P17210|KINH_DROME Kinesin heavy chain
          Length = 975

 Score =  268 bits (685), Expect = 2e-71
 Identities = 156/311 (50%), Positives = 198/311 (63%), Gaps = 1/311 (0%)
 Frame = +1

Query: 1    EFEVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQL-IVNANAQNRAEILAGQ 177
            + E RM +L   + E E +KR LEEQ D L  E +K KA E +  VNA  + RAE     
Sbjct: 662  QHEARMKSLQESMREAENKKRTLEEQIDSLREECAKLKAAEHVSAVNAEEKQRAE----- 716

Query: 178  LDIKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKV 357
             +++S  D +     E +++Q+ ELRD++  KQ   +EMKD    L   ++++  DYEKV
Sbjct: 717  -ELRSMFDSQMDELREAHTRQVSELRDEIAAKQHEMDEMKDVHQKLLLAHQQMTADYEKV 775

Query: 358  VAEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKS 537
              E   K+++L+ I    E+REQAR+DLKGLEDTV KELQTLHNLRKLFVQDL  R++K+
Sbjct: 776  RQEDAEKSSELQNIILTNERREQARKDLKGLEDTVAKELQTLHNLRKLFVQDLQQRIRKN 835

Query: 538  TRGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXX 717
               VN                  +L QKQKI FLE NL+QLTKVHKQLVRDN+D      
Sbjct: 836  V--VNEESEEDGG----------SLAQKQKISFLENNLDQLTKVHKQLVRDNADLRCELP 883

Query: 718  XXXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIA 897
                    T ERVKALE+ALK+AKEGAMRDR+RYQ+EVDRIKEAVRQ+++ RRG   QIA
Sbjct: 884  KLEKRLRCTMERVKALETALKEAKEGAMRDRKRYQYEVDRIKEAVRQKHLGRRGPQAQIA 943

Query: 898  KPIRAGHAPSA 930
            KPIR+G    A
Sbjct: 944  KPIRSGQGAIA 954


 Score = 40.4 bits (93), Expect = 0.009
 Identities = 43/182 (23%), Positives = 80/182 (43%), Gaps = 6/182 (3%)
 Frame = +1

Query: 7   EVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQLDI 186
           E     L  +  +T   +  L  Q   L    +    NEQ    A      E L  QLD 
Sbjct: 395 EASTPNLEVEAAQTAAAEAALAAQRTALANMSASVAVNEQ----ARLATECERLYQQLDD 450

Query: 187 KSKLDEEFKRQS---EQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKV 357
           K   DEE  +QS   EQ  +Q+ E  + +   +R  E ++ ++  +  +NE  KE+ ++V
Sbjct: 451 K---DEEINQQSQYAEQLKEQVMEQEELIANARREYETLQSEMARIQQENESAKEEVKEV 507

Query: 358 VAEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQ---DLSNRV 528
           +   E  A      ++ +++ +   +D+  L +  +++ Q++ N     +Q   D+S+  
Sbjct: 508 LQALEELAV---NYDQKSQEIDNKNKDIDALNEE-LQQKQSVFNAASTELQQLKDMSSHQ 563

Query: 529 KK 534
           KK
Sbjct: 564 KK 565

>sp|O60282|KIF5C_HUMAN Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific
            2)
          Length = 957

 Score =  265 bits (676), Expect = 2e-70
 Identities = 148/314 (47%), Positives = 199/314 (63%), Gaps = 3/314 (0%)
 Frame = +1

Query: 1    EFEVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQL 180
            + E ++ +L + +   E ++R+LEE  D L  E++K +A E++   +      E L    
Sbjct: 635  QHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQ 694

Query: 181  D---IKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYE 351
            D   +K  L+++ +   E + +Q+  LRD+++EKQ+  +E++D    L  + EKL  DY 
Sbjct: 695  DAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYN 754

Query: 352  KVVAEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVK 531
            K+  E + +  KLE +    +KREQAR+DLKGLE+TV +ELQTLHNLRKLFVQDL+ RVK
Sbjct: 755  KLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVK 814

Query: 532  KSTRGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXX 711
            KS    N                  +  QKQKI FLE NLEQLTKVHKQLVRDN+D    
Sbjct: 815  KSVELDNDDGGG-------------SAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCE 861

Query: 712  XXXXXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQ 891
                     +T ERVKALESALK+AKE AMRDR+RYQ EVDRIKEAVR +N+ARR ++ Q
Sbjct: 862  LPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQ 921

Query: 892  IAKPIRAGHAPSAS 933
            IAKPIR GH P++S
Sbjct: 922  IAKPIRPGHYPASS 935


 Score = 37.0 bits (84), Expect = 0.10
 Identities = 42/174 (24%), Positives = 78/174 (44%)
 Frame = +1

Query: 22  TLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQLDIKSKLD 201
           TL N +   E++  +   +N +   E  +  A +Q   N    +   I+     + + + 
Sbjct: 355 TLKNVIQHLEMELNRW--RNGEAVPEDEQISAKDQK--NLEPCDNTPIIDNIAPVVAGIS 410

Query: 202 EEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKVVAEGEIKA 381
            E K   E+Y ++I  L  +LD+K        D+I+  S   EKLK   ++++ + E+ A
Sbjct: 411 TEEK---EKYDEEISSLYRQLDDKD-------DEINQQSQLAEKLK---QQMLDQDELLA 457

Query: 382 AKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTR 543
           +     EK  E+  + + + +  +D V + LQ L  L   + Q  S  V+  TR
Sbjct: 458 STRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQK-SQEVEDKTR 510

>sp|P28738|KIF5C_MOUSE Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific
            2)
          Length = 956

 Score =  263 bits (672), Expect = 7e-70
 Identities = 147/314 (46%), Positives = 197/314 (62%), Gaps = 3/314 (0%)
 Frame = +1

Query: 1    EFEVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQL 180
            + E ++ +L + +   E ++R+LEE  D L  E++K +A E++   +      E L    
Sbjct: 634  QHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQ 693

Query: 181  D---IKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYE 351
            D   +K  L+++ +   E + +Q+  LRD+++EKQR  +E++D    L  + E+L  DY 
Sbjct: 694  DAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYN 753

Query: 352  KVVAEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVK 531
            K+  E + +  KLE +    +KREQAR+DLKGLE+TV  ELQTLHNLRKLFVQDL+ RVK
Sbjct: 754  KLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSIELQTLHNLRKLFVQDLTTRVK 813

Query: 532  KSTRGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXX 711
            KS                       +  QKQKI FLE NLEQLTKVHKQLVRDN+D    
Sbjct: 814  KSVE-------------LDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCE 860

Query: 712  XXXXXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQ 891
                     +T ERVKALESALK+AKE AMRDR+RYQ EVDRIKEAVR +N+ARR ++ Q
Sbjct: 861  LPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQ 920

Query: 892  IAKPIRAGHAPSAS 933
            IAKPIR GH P++S
Sbjct: 921  IAKPIRPGHYPASS 934

>sp|P33175|KINN_MOUSE Neuronal kinesin heavy chain (NKHC) (Kinesin heavy chain isoform 5A)
            (Kinesin heavy chain neuron-specific 1)
          Length = 1027

 Score =  254 bits (649), Expect = 3e-67
 Identities = 142/315 (45%), Positives = 198/315 (62%)
 Frame = +1

Query: 1    EFEVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQL 180
            + E ++ +L   +   EL+KR LEE  D L  E+++ +A+E +   A      +    + 
Sbjct: 635  QHEAKIRSLTEYMQTVELKKRHLEESYDSLSDELARLQAHETVHEVALKDKEPDTQDAE- 693

Query: 181  DIKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKVV 360
            ++K  L+ + +   E + +Q+  LRD+++EKQ+  +E+KD    L  + EKL+ DYE++ 
Sbjct: 694  EVKKALELQMENHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYERLK 753

Query: 361  AEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKST 540
             E   K+AKL+ +    E+ EQ++QDLKGLE+TV +ELQTLHNLRKLFVQD++ RVKKS 
Sbjct: 754  NEENEKSAKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSA 813

Query: 541  RGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXX 720
                                     QKQKI FLE NLEQLTKVHKQLVRDN+D       
Sbjct: 814  EMEPEDSGGIHS-------------QKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK 860

Query: 721  XXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAK 900
                  +T ERVKALE ALK+AKEGAM+D+RRYQ EVDRIKEAVR ++  +RG++ QIAK
Sbjct: 861  LEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAK 920

Query: 901  PIRAGHAPSASQISP 945
            P+R GH P++S  +P
Sbjct: 921  PVRPGHYPASSPTNP 935

>sp|Q12840|KINN_HUMAN Neuronal kinesin heavy chain (NKHC) (Kinesin heavy chain isoform 5A)
            (Kinesin heavy chain neuron-specific 1)
          Length = 1032

 Score =  253 bits (645), Expect = 9e-67
 Identities = 142/315 (45%), Positives = 195/315 (61%)
 Frame = +1

Query: 1    EFEVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQL 180
            + E ++ +L   +   EL+KR LEE  D L  E++K +A E +   A      +      
Sbjct: 635  QHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDAD- 693

Query: 181  DIKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKVV 360
            ++K  L+ + +   E + +Q+  LRD+++EKQ+  +E+KD    L  + EKL+ DYEK+ 
Sbjct: 694  EVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLK 753

Query: 361  AEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKST 540
            +E   K+ KL+ +    E+ EQ++QDLKGLE+TV +ELQTLHNLRKLFVQD++ RVKKS 
Sbjct: 754  SEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSA 813

Query: 541  RGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXX 720
                                     QKQKI FLE NLEQLTKVHKQLVRDN+D       
Sbjct: 814  EMEPEDSGGIHS-------------QKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK 860

Query: 721  XXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAK 900
                  +T ERVKALE ALK+AKEGAM+D+RRYQ EVDRIKEAVR ++  +R ++ QIAK
Sbjct: 861  LEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRAHSAQIAK 920

Query: 901  PIRAGHAPSASQISP 945
            P+R GH P++S  +P
Sbjct: 921  PVRPGHYPASSPTNP 935

>sp|P33176|KINH_HUMAN Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC)
          Length = 963

 Score =  252 bits (643), Expect = 2e-66
 Identities = 141/315 (44%), Positives = 196/315 (62%)
 Frame = +1

Query: 1    EFEVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQL 180
            + E ++ +L   +   E +KR+LEE  D L  E+ + +A E+  V+   +     +    
Sbjct: 638  QHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEK--VHEMEKEHLNKVQTAN 695

Query: 181  DIKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKVV 360
            ++K  ++++ +   E + +QI  LRD+++ K +   +++D+   +  + E+L+ ++EK+ 
Sbjct: 696  EVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLK 755

Query: 361  AEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKST 540
            A  + K+ KL  +    ++REQARQDLKGLE+TV KELQTLHNLRKLFVQDL+ RVKKS 
Sbjct: 756  ATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSA 815

Query: 541  RGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXX 720
                                  +  QKQKI FLE NLEQLTKVHKQLVRDN+D       
Sbjct: 816  E-------------IDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK 862

Query: 721  XXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAK 900
                  +T ERVKALESALK+AKE A RDR+RYQ EVDRIKEAVR +N+ARRG++ QIAK
Sbjct: 863  LEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSAQIAK 922

Query: 901  PIRAGHAPSASQISP 945
            PIR G  P+AS   P
Sbjct: 923  PIRPGQHPAASPTHP 937


 Score = 33.9 bits (76), Expect = 0.85
 Identities = 37/169 (21%), Positives = 75/169 (44%), Gaps = 6/169 (3%)
 Frame = +1

Query: 46  TELQKRKLEEQNDQLHAEVS----KFKANEQLIVNANAQ--NRAEILAGQLDIKSKLDEE 207
           T+ ++RK EE+  +L+ ++     +     QL+     Q  ++ E+LA     +  +  E
Sbjct: 414 TDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAE 473

Query: 208 FKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKVVAEGEIKAAK 387
             R   +     +E+++ L    +A EE+       S + E   ++YE +  E   K+A 
Sbjct: 474 LNRLQAENDASKEEVKEVL----QALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSAT 529

Query: 388 LEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKK 534
           L  I+   +K ++     K     +M  L  L +L ++ +   +N VK+
Sbjct: 530 LASIDAELQKLKEMTNHQKKRAAEMMASL--LKDLAEIGIAVGNNDVKQ 576

>sp|Q61768|KINH_MOUSE Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC)
          Length = 963

 Score =  251 bits (641), Expect = 3e-66
 Identities = 140/315 (44%), Positives = 197/315 (62%)
 Frame = +1

Query: 1    EFEVRMNTLNNKVDETELQKRKLEEQNDQLHAEVSKFKANEQLIVNANAQNRAEILAGQL 180
            + E ++ +L   +   E +KR+LEE  D L  E+ + +A E+  V+   +     +    
Sbjct: 638  QHEAKIKSLTEYLQNDEQKKRQLEESLDSLGEELVQLRAQEK--VHEMEKEHLNKVQTAN 695

Query: 181  DIKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKVV 360
            ++K  ++++ +   E + +QI  LRD+++ K++   +++D+   +  + E+L+ ++E++ 
Sbjct: 696  EVKQAVEQQIQSHRETHQKQISSLRDEVEAKEKLITDLQDQNQKMVLETERLRVEHERLK 755

Query: 361  AEGEIKAAKLEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKST 540
            A  + K+ KL  +    ++REQARQDLKGLE+TV KELQTLHNLRKLFVQDL+ RVKKS 
Sbjct: 756  ATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSA 815

Query: 541  RGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXX 720
                                  +  QKQKI FLE NLEQLTKVHKQLVRDN+D       
Sbjct: 816  E-------------VDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK 862

Query: 721  XXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAK 900
                  +T ERVKALESALK+AKE A RDR+RYQ EVDRIKEAVR +N+ARRG++ QIAK
Sbjct: 863  LEFRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSAQIAK 922

Query: 901  PIRAGHAPSASQISP 945
            PIR G  P+AS   P
Sbjct: 923  PIRPGQHPAASPTHP 937


 Score = 35.0 bits (79), Expect = 0.38
 Identities = 37/169 (21%), Positives = 75/169 (44%), Gaps = 6/169 (3%)
 Frame = +1

Query: 46  TELQKRKLEEQNDQLHAEVS----KFKANEQLIVNANAQ--NRAEILAGQLDIKSKLDEE 207
           T+ ++RK EE+  +L+ ++     +     QL+     Q  ++ E+LA     +  +  E
Sbjct: 414 TDAERRKCEEELAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAE 473

Query: 208 FKRQSEQYSQQIKELRDKLDEKQRASEEMKDKIHHLSFQNEKLKEDYEKVVAEGEIKAAK 387
             R   +     +E+++ L    +A EE+       S + E   ++YE +  E   K+A 
Sbjct: 474 LNRLQAENDASKEEVKEVL----QALEELAVNYDQKSQEVEDKTKEYELLTDEFNQKSAT 529

Query: 388 LEGIEKATEKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKK 534
           L  I+   +K ++     K     +M  L  L +L ++ +   +N VK+
Sbjct: 530 LASIDAELQKLKEMTNHQKKRAAEMMASL--LKDLAEIGIAVGNNDVKQ 576

>sp|P34540|KINH_CAEEL Kinesin heavy chain (Uncoordinated protein 116)
          Length = 815

 Score =  131 bits (329), Expect = 4e-30
 Identities = 115/378 (30%), Positives = 175/378 (46%), Gaps = 76/378 (20%)
 Frame = +1

Query: 25   LNNKVDETELQKRKLEEQNDQLHAE---VSKFKANEQLIVNANAQNRAEI---------- 165
            L+ K DE +   ++LE+   Q+  +   +   + NE+LI   N + + E           
Sbjct: 442  LDEKDDEIQKVSQELEKLRQQVLLQEEALGTMRENEELIREENNRFQKEAEDKQQEGKEM 501

Query: 166  ------LAGQLDIKSKLDEEFKRQSEQYSQQIKELRDKLDEKQRAS----EEMKDKIHH- 312
                  +A  LD++    E+ KR+ E   +  + L D++++         +E   KI H 
Sbjct: 502  MTALEEIAVNLDVRQAECEKLKRELEVVQEDNQSLEDRMNQATSLLNAHLDECGPKIRHF 561

Query: 313  ---------------LSFQNEKL-----------------------KEDYEKVVAEGEIK 378
                           ++ QN++L                       KE       + E K
Sbjct: 562  KEGIYNVIREFNIADIASQNDQLPDHDLLNHVRIGVSKLFSEYSAAKESSTAAEHDAEAK 621

Query: 379  -AAKLEGIEKATEK--------REQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVK 531
             AA +  +E   +         ++QA +++K L D V  EL TL NL+K F++ L  R +
Sbjct: 622  LAADVARVESGQDAGRMKQLLVKDQAAKEIKPLTDRVNMELTTLKNLKKEFMRVLVARCQ 681

Query: 532  --KSTRGVNXXXXXXXXXXXXXXXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXX 705
              + T G +                     QKQ+IQFLE NL++LTKVHKQLVRDN+D  
Sbjct: 682  ANQDTEGEDSLSGP---------------AQKQRIQFLENNLDKLTKVHKQLVRDNADLR 726

Query: 706  XXXXXXXXXXXSTTERVKALESALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNA 885
                          +R+K LE+AL+D+K+ +  +R++YQ EV+RIKEAVRQRN+ RR NA
Sbjct: 727  VELPKMEARLRGREDRIKILETALRDSKQRSQAERKKYQQEVERIKEAVRQRNM-RRMNA 785

Query: 886  PQIAKPIRAGH---APSA 930
            PQI KPIR G    +PSA
Sbjct: 786  PQIVKPIRPGQVYTSPSA 803

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,889,287
Number of Sequences: 369166
Number of extensions: 1518937
Number of successful extensions: 10726
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8372
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10176
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 12106823640
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00022

  1. Dr_sW_001_I11
  2. Dr_sW_025_P15