Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_P15
(693 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P21613|KINH_LOLPE Kinesin heavy chain 206 5e-53
sp|P33176|KINH_HUMAN Kinesin heavy chain (Ubiquitous kinesi... 199 8e-51
sp|Q61768|KINH_MOUSE Kinesin heavy chain (Ubiquitous kinesi... 199 8e-51
sp|O60282|KIF5C_HUMAN Kinesin heavy chain isoform 5C (Kines... 198 1e-50
sp|P35978|KINH_STRPU Kinesin heavy chain 196 4e-50
sp|P28738|KIF5C_MOUSE Kinesin heavy chain isoform 5C (Kines... 196 6e-50
sp|P17210|KINH_DROME Kinesin heavy chain 192 9e-49
sp|P33175|KINN_MOUSE Neuronal kinesin heavy chain (NKHC) (K... 189 8e-48
sp|Q12840|KINN_HUMAN Neuronal kinesin heavy chain (NKHC) (K... 186 4e-47
sp|P34540|KINH_CAEEL Kinesin heavy chain (Uncoordinated pro... 127 3e-29
>sp|P21613|KINH_LOLPE Kinesin heavy chain
Length = 967
Score = 206 bits (524), Expect = 5e-53
Identities = 113/174 (64%), Positives = 125/174 (71%)
Frame = +2
Query: 5 EKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTRGVNXXXXXXXXXXXXX 184
++REQA+QDLKGLE+TV KELQTLHNLRKLFVQDL N+VKKS
Sbjct: 771 DRREQAKQDLKGLEETVAKELQTLHNLRKLFVQDLQNKVKKSCSKTEEEDEDTGG----- 825
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
N QKQKI FLE NLEQLTKVHKQLVRDN+D +T ERVK+LES
Sbjct: 826 -----NAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATMERVKSLES 880
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGHAPSAS 526
ALKDAKEGAMRDR+RYQHEVDRIKEAVRQ+N+ARRG+A QIAKPIR G S S
Sbjct: 881 ALKDAKEGAMRDRKRYQHEVDRIKEAVRQKNLARRGHAAQIAKPIRPGQHQSVS 934
>sp|P33176|KINH_HUMAN Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC)
Length = 963
Score = 199 bits (505), Expect = 8e-51
Identities = 110/178 (61%), Positives = 124/178 (69%)
Frame = +2
Query: 5 EKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTRGVNXXXXXXXXXXXXX 184
++REQARQDLKGLE+TV KELQTLHNLRKLFVQDL+ RVKKS
Sbjct: 773 DRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAE-------------IDS 819
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
+ QKQKI FLE NLEQLTKVHKQLVRDN+D +T ERVKALES
Sbjct: 820 DDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALES 879
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGHAPSASQISP 538
ALK+AKE A RDR+RYQ EVDRIKEAVR +N+ARRG++ QIAKPIR G P+AS P
Sbjct: 880 ALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHP 937
>sp|Q61768|KINH_MOUSE Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC)
Length = 963
Score = 199 bits (505), Expect = 8e-51
Identities = 110/178 (61%), Positives = 124/178 (69%)
Frame = +2
Query: 5 EKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTRGVNXXXXXXXXXXXXX 184
++REQARQDLKGLE+TV KELQTLHNLRKLFVQDL+ RVKKS
Sbjct: 773 DRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAE-------------VDS 819
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
+ QKQKI FLE NLEQLTKVHKQLVRDN+D +T ERVKALES
Sbjct: 820 DDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEFRLRATAERVKALES 879
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGHAPSASQISP 538
ALK+AKE A RDR+RYQ EVDRIKEAVR +N+ARRG++ QIAKPIR G P+AS P
Sbjct: 880 ALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHP 937
>sp|O60282|KIF5C_HUMAN Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific
2)
Length = 957
Score = 198 bits (504), Expect = 1e-50
Identities = 109/174 (62%), Positives = 125/174 (71%)
Frame = +2
Query: 5 EKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTRGVNXXXXXXXXXXXXX 184
+KREQAR+DLKGLE+TV +ELQTLHNLRKLFVQDL+ RVKKS N
Sbjct: 775 DKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGG-------- 826
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
+ QKQKI FLE NLEQLTKVHKQLVRDN+D +T ERVKALES
Sbjct: 827 -----SAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALES 881
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGHAPSAS 526
ALK+AKE AMRDR+RYQ EVDRIKEAVR +N+ARR ++ QIAKPIR GH P++S
Sbjct: 882 ALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASS 935
>sp|P35978|KINH_STRPU Kinesin heavy chain
Length = 1031
Score = 196 bits (499), Expect = 4e-50
Identities = 106/171 (61%), Positives = 123/171 (71%)
Frame = +2
Query: 5 EKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTRGVNXXXXXXXXXXXXX 184
++REQA+QDLKGLE+TV KELQTLHNLRKLFV DL NRVKK+ G +
Sbjct: 768 DRREQAKQDLKGLEETVAKELQTLHNLRKLFVSDLQNRVKKALEGGDRDDDSGG------ 821
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
+ QKQKI FLE NLEQLTKVHKQLVRDN+D +T+ERVKALE
Sbjct: 822 -----SQAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLERRLRATSERVKALEM 876
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGHAP 517
+LK+ KEGAMRDR+RYQ EVDRI+EAVRQRN A+RG++ QIAK IRAGH P
Sbjct: 877 SLKETKEGAMRDRKRYQQEVDRIREAVRQRNFAKRGSSAQIAKAIRAGHPP 927
>sp|P28738|KIF5C_MOUSE Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific
2)
Length = 956
Score = 196 bits (497), Expect = 6e-50
Identities = 108/174 (62%), Positives = 123/174 (70%)
Frame = +2
Query: 5 EKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTRGVNXXXXXXXXXXXXX 184
+KREQAR+DLKGLE+TV ELQTLHNLRKLFVQDL+ RVKKS
Sbjct: 774 DKREQAREDLKGLEETVSIELQTLHNLRKLFVQDLTTRVKKSVE-------------LDS 820
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
+ QKQKI FLE NLEQLTKVHKQLVRDN+D +T ERVKALES
Sbjct: 821 DDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALES 880
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGHAPSAS 526
ALK+AKE AMRDR+RYQ EVDRIKEAVR +N+ARR ++ QIAKPIR GH P++S
Sbjct: 881 ALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASS 934
>sp|P17210|KINH_DROME Kinesin heavy chain
Length = 975
Score = 192 bits (487), Expect = 9e-49
Identities = 107/173 (61%), Positives = 123/173 (71%)
Frame = +2
Query: 5 EKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTRGVNXXXXXXXXXXXXX 184
E+REQAR+DLKGLEDTV KELQTLHNLRKLFVQDL R++K+ VN
Sbjct: 794 ERREQARKDLKGLEDTVAKELQTLHNLRKLFVQDLQQRIRKNV--VNEESEEDGG----- 846
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
+L QKQKI FLE NL+QLTKVHKQLVRDN+D T ERVKALE+
Sbjct: 847 -----SLAQKQKISFLENNLDQLTKVHKQLVRDNADLRCELPKLEKRLRCTMERVKALET 901
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGHAPSA 523
ALK+AKEGAMRDR+RYQ+EVDRIKEAVRQ+++ RRG QIAKPIR+G A
Sbjct: 902 ALKEAKEGAMRDRKRYQYEVDRIKEAVRQKHLGRRGPQAQIAKPIRSGQGAIA 954
>sp|P33175|KINN_MOUSE Neuronal kinesin heavy chain (NKHC) (Kinesin heavy chain isoform 5A)
(Kinesin heavy chain neuron-specific 1)
Length = 1027
Score = 189 bits (479), Expect = 8e-48
Identities = 102/178 (57%), Positives = 123/178 (69%)
Frame = +2
Query: 5 EKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTRGVNXXXXXXXXXXXXX 184
E+ EQ++QDLKGLE+TV +ELQTLHNLRKLFVQD++ RVKKS
Sbjct: 771 ERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHS----- 825
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
QKQKI FLE NLEQLTKVHKQLVRDN+D +T ERVKALE
Sbjct: 826 --------QKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEG 877
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGHAPSASQISP 538
ALK+AKEGAM+D+RRYQ EVDRIKEAVR ++ +RG++ QIAKP+R GH P++S +P
Sbjct: 878 ALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNP 935
>sp|Q12840|KINN_HUMAN Neuronal kinesin heavy chain (NKHC) (Kinesin heavy chain isoform 5A)
(Kinesin heavy chain neuron-specific 1)
Length = 1032
Score = 186 bits (473), Expect = 4e-47
Identities = 101/178 (56%), Positives = 122/178 (68%)
Frame = +2
Query: 5 EKREQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVKKSTRGVNXXXXXXXXXXXXX 184
E+ EQ++QDLKGLE+TV +ELQTLHNLRKLFVQD++ RVKKS
Sbjct: 771 ERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHS----- 825
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
QKQKI FLE NLEQLTKVHKQLVRDN+D +T ERVKALE
Sbjct: 826 --------QKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEG 877
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGHAPSASQISP 538
ALK+AKEGAM+D+RRYQ EVDRIKEAVR ++ +R ++ QIAKP+R GH P++S +P
Sbjct: 878 ALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRAHSAQIAKPVRPGHYPASSPTNP 935
>sp|P34540|KINH_CAEEL Kinesin heavy chain (Uncoordinated protein 116)
Length = 815
Score = 127 bits (319), Expect = 3e-29
Identities = 79/176 (44%), Positives = 107/176 (60%), Gaps = 5/176 (2%)
Frame = +2
Query: 11 REQARQDLKGLEDTVMKELQTLHNLRKLFVQDLSNRVK--KSTRGVNXXXXXXXXXXXXX 184
++QA +++K L D V EL TL NL+K F++ L R + + T G +
Sbjct: 644 KDQAAKEIKPLTDRVNMELTTLKNLKKEFMRVLVARCQANQDTEGEDSLSGP-------- 695
Query: 185 XXXXXNLVQKQKIQFLEMNLEQLTKVHKQLVRDNSDXXXXXXXXXXXXXSTTERVKALES 364
QKQ+IQFLE NL++LTKVHKQLVRDN+D +R+K LE+
Sbjct: 696 -------AQKQRIQFLENNLDKLTKVHKQLVRDNADLRVELPKMEARLRGREDRIKILET 748
Query: 365 ALKDAKEGAMRDRRRYQHEVDRIKEAVRQRNIARRGNAPQIAKPIRAGH---APSA 523
AL+D+K+ + +R++YQ EV+RIKEAVRQRN+ RR NAPQI KPIR G +PSA
Sbjct: 749 ALRDSKQRSQAERKKYQQEVERIKEAVRQRNM-RRMNAPQIVKPIRPGQVYTSPSA 803
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,119,637
Number of Sequences: 369166
Number of extensions: 984619
Number of successful extensions: 3602
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3348
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3576
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5976365205
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)