Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00016 (1001 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P55884|IF39_HUMAN Eukaryotic translation initiation fact... 189 1e-47 sp|P56821|IF39_TOBAC Eukaryotic translation initiation fact... 142 2e-33 sp|Q10425|IF39_SCHPO Probable eukaryotic translation initia... 141 3e-33 sp|Q9C5Z1|IF39_ARATH Eukaryotic translation initiation fact... 140 7e-33 sp|P06103|IF39_YEAST Eukaryotic translation initiation fact... 117 4e-26 sp|Q7VKU3|TOLB_HAEDU TolB protein precursor 42 0.003 sp|Q8BHJ5|TBL1R_MOUSE F-box-like/WD-repeat protein TBL1XR1 ... 39 0.030 sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD-repeat protein TBL1XR1 ... 39 0.030 sp|P14197|AAC3_DICDI AAC-rich mRNA clone AAC3 protein 37 0.067 sp|Q9A3H4|TOLB_CAUCR TolB protein precursor 37 0.088
>sp|P55884|IF39_HUMAN Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) Length = 814 Score = 189 bits (479), Expect = 1e-47 Identities = 102/302 (33%), Positives = 171/302 (56%), Gaps = 2/302 (0%) Frame = +3 Query: 3 IDIVGVKDFTWSSKGHLISYWVGEQESTPARIVLISLPSKKEIFAKTLFNVADISLKWSS 182 + I G+KDF+WS G++I++WV E + PAR+ L+ LP+++EI + LFNV D L W Sbjct: 462 LKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQK 521 Query: 183 QDDFLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITINEKTQIVANDWE 362 D+L V +R K G+ + EI+R++EK++PV+ + + E I+A WE Sbjct: 522 NGDYLCVKVDRTPKGTQ--------GVVTNFEIFRMREKQVPVDVVEMKE--TIIAFAWE 571 Query: 363 ANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTILKWSPSGQFIACSSPNS 542 NG+KFA+L ++ Y +K +G+ + I F TI WSP GQF+ + S Sbjct: 572 PNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIF-WSPQGQFVVLAGLRS 630 Query: 543 --SSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMSYRLNLINETDGGGVSFHSITGR 716 ++ F+D + V+ E +D+ WDPTGRY+++ ++ D + GR Sbjct: 631 MNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVD-NAYWLWTFQGR 689 Query: 717 LLMERNYQGLKQIIWRPRPSCLLSEQDIRNIKKNMAKFNQQFAHQDEMMSNETKRKLMEH 896 LL + N Q++WRPRP LLS++ I+ IKK++ K+++ F +D + ++ ++L+E Sbjct: 690 LLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVER 749 Query: 897 RQ 902 R+ Sbjct: 750 RR 751
Score = 31.2 bits (69), Expect = 4.8 Identities = 20/77 (25%), Positives = 37/77 (48%) Frame = +3 Query: 414 ILIYDLKLSGQTQKIMDFGFSSRMTILKWSPSGQFIACSSPNSSSIEFIDGHEGVVLKRV 593 I+I+D+ L+G ++ S+ I KWS G+F A + ++ SI + K + Sbjct: 404 IIIWDI-LTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSL 462 Query: 594 ETNNMNDLVWDPTGRYL 644 + + + D W P G + Sbjct: 463 KISGIKDFSWSPGGNII 479
>sp|P56821|IF39_TOBAC Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p110) (eIF3b) Length = 719 Score = 142 bits (357), Expect = 2e-33 Identities = 100/341 (29%), Positives = 168/341 (49%), Gaps = 12/341 (3%) Frame = +3 Query: 3 IDIVGVKDFTWSSKGHLISYWVGEQESTPARIVLISLPSKKEIFAKTLFNVADISLKWSS 182 I + V DF+WS +++ +V E + PAR+ L+ +PSK+E+ K LF+V+D + W S Sbjct: 359 IKVENVMDFSWSPADPILALFVPECGNQPARVSLVQIPSKEELRQKNLFSVSDCKMYWQS 418 Query: 183 QDDFLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITI-NEKTQIVANDW 359 D+LAV +RY K K + Y G E++R+KE++IP+E + + N +I A W Sbjct: 419 NGDYLAVKVDRYTKTK----KSTYTG----FELFRIKERDIPIEVLELDNTNDKIPAFGW 470 Query: 360 EANGTKFAIL-TFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTILK--------WSPSG 512 G+ + +I Y + + T G S++T LK WSP G Sbjct: 471 GPEGSPICCYPSVTTPRPDIRFYSVPVWALTP-----GLVSKLTTLKGKQANALYWSPGG 525 Query: 513 QFIACSSPN--SSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMSYRLNLINETDGG 686 +F+ + + +EF D E + E D+ WDPTGRY+ + + ++E + Sbjct: 526 RFLILTGLKGFNGQLEFFDVDELETMASAEHFMATDVEWDPTGRYVAT-SVTSVHEME-N 583 Query: 687 GVSFHSITGRLLMERNYQGLKQIIWRPRPSCLLSEQDIRNIKKNMAKFNQQFAHQDEMMS 866 G + S G+LL Q +WRPRP LS++ I KN+ ++++++ +D+ +S Sbjct: 584 GFNIWSFNGKLLYRILKDHFFQYLWRPRPPSFLSKEKEEEIAKNLKRYSKKYEAEDQDVS 643 Query: 867 NETKRKLMEHRQN*CRNMAVKLALTASHNESCRLHENTSIQ 989 + + E R+ +K A NE RLHE ++ Sbjct: 644 LQLSEQDREKRKK------LKEEWEAWINEWKRLHEEEKME 678
>sp|Q10425|IF39_SCHPO Probable eukaryotic translation initiation factor 3 90 kDa subunit (eIF3 p90) Length = 725 Score = 141 bits (355), Expect = 3e-33 Identities = 107/339 (31%), Positives = 160/339 (47%), Gaps = 39/339 (11%) Frame = +3 Query: 3 IDIVGVKDFTW---------SSKGHLISYWVGEQESTPARIVLISLPSKKEIFAKTLFNV 155 I I GV++F W SK L++YW E + PAR+ LIS+PSK I K LFNV Sbjct: 347 IKIDGVQNFEWCPVSDALGRDSKEQLLAYWTPEITNQPARVALISIPSKSTIRTKNLFNV 406 Query: 156 ADISLKWSSQDDFLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITINEK 335 +D L W S D+L V +R+ K K ++LEI+R++EK IPVE + + K Sbjct: 407 SDCKLYWQSNGDYLCVKVDRHTKTKK--------STFSNLEIFRIREKNIPVEVVDL--K 456 Query: 336 TQIVANDWEANGTKFAILTFNQK-------STNILIYDLKLSGQT----QKIMDFGFSSR 482 ++ WE +FAI++ N + TN+ Y + T + I+ F Sbjct: 457 DVVLNFAWEPKSDRFAIISANDQVLNSTNVKTNLSFYGFEQKKNTPSTFRHIITFD-KKT 515 Query: 483 MTILKWSPSGQFIACSSPNSSS---IEFID------GHEGVVLKRV------ETNNMNDL 617 L +P G+F+ ++ SS+ +EF D E L V E M +L Sbjct: 516 CNSLFMAPKGRFMVAATLGSSTQYDLEFYDLDFDTEKKEPDALANVQQIGSAEHFGMTEL 575 Query: 618 VWDPTGRYLMS----YRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWRPRPSCLL 785 WDP+GRY+ + +R L N G G LL E KQ IWRPRP L Sbjct: 576 EWDPSGRYVTTSSTIWRHKLEN-----GYRLCDFRGTLLREEMIGEFKQFIWRPRPPSPL 630 Query: 786 SEQDIRNIKKNMAKFNQQFAHQDEMMSNETKRKLMEHRQ 902 +++D++ I+K + +N+ F +D + R+L R+ Sbjct: 631 TKEDMKKIRKKLKDYNRLFDEEDIAEQSSANRELAARRR 669
>sp|Q9C5Z1|IF39_ARATH Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p110) (eIF3b) (p82) Length = 712 Score = 140 bits (352), Expect = 7e-33 Identities = 85/290 (29%), Positives = 153/290 (52%), Gaps = 7/290 (2%) Frame = +3 Query: 18 VKDFTWSSKGHLISYWVGEQE--STPARIVLISLPSKKEIFAKTLFNVADISLKWSSQDD 191 V D WS ++S +V EQ + PA++ L+ +PSK E+ K LF+V+D + W S + Sbjct: 360 VVDICWSPTDSILSLFVPEQGGGNQPAKVALVQIPSKVELRQKNLFSVSDCKMYWQSSGE 419 Query: 192 FLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITI-NEKTQIVANDWEAN 368 +LAV +RY K K + Y G E++R+KE++IP+E + + N+ +I+A WE Sbjct: 420 YLAVKVDRYTKTK----KSTYSG----FELFRIKERDIPIEVLELDNKNDKIIAFAWEPK 471 Query: 369 GTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGF--SSRMTILKWSPSGQFIACSSPN- 539 G +FA++ +Q ++ Y +K + T ++ + + L WSP+G++I + Sbjct: 472 GHRFAVIHGDQPRPDVSFYSMKTAQNTGRVSKLATLKAKQANALFWSPTGKYIILAGLKG 531 Query: 540 -SSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMSYRLNLINETDGGGVSFHSITGR 716 + +EF + E + E D+ WDPTGRY+ + + ++E + G + S G Sbjct: 532 FNGQLEFFNVDELETMATAEHFMATDIEWDPTGRYVAT-AVTSVHEME-NGFTIWSFNGI 589 Query: 717 LLMERNYQGLKQIIWRPRPSCLLSEQDIRNIKKNMAKFNQQFAHQDEMMS 866 +L Q+ WRPRP L+ + I K + K+++++ +D+ +S Sbjct: 590 MLYRILKDHFFQLAWRPRPPSFLTAEKEEEIAKTLKKYSKKYEAEDQDVS 639
>sp|P06103|IF39_YEAST Eukaryotic translation initiation factor 3 90 kDa subunit (eIF3 p90) (Cell cycle regulation and translation initiation protein) Length = 763 Score = 117 bits (294), Expect = 4e-26 Identities = 84/344 (24%), Positives = 161/344 (46%), Gaps = 48/344 (13%) Frame = +3 Query: 15 GVKDFTWSSKGH-------------LISYWVGEQESTPARIVLISLPSKKEIFAKTLFNV 155 G++DF+++ +G L++YW E ++ + +P + + L V Sbjct: 377 GIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQV 436 Query: 156 ADISLKWSSQDDFLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITINEK 335 ++++L W +Q +FL ER+ K + ++L+I R+ E++IPVEK+ + K Sbjct: 437 SNVTLHWQNQAEFLCFNVERHTKSGKTQF--------SNLQICRLTERDIPVEKVEL--K 486 Query: 336 TQIVANDWEANGTKFAILTFNQ--------KSTNILIYDLKLSGQTQKIMDFGFSSRM-- 485 + WE +G +F ++ ++ + I Y + +T I + + Sbjct: 487 DSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPK 546 Query: 486 ---TILKWSPSGQFI---ACSSPNS--SSIEFID-GHEGVVLKRVETNN----------- 605 + WSP+G+F+ A PN S ++F D + G K + NN Sbjct: 547 TFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGE--KNINDNNDVSASLKDVAH 604 Query: 606 -----MNDLVWDPTGRYLMSYRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWRPR 770 ++ WDP+GRY+ ++ +L ++ + G F+ I G L+ E G K WRPR Sbjct: 605 PTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFN-IAGNLVKEDIIAGFKNFAWRPR 663 Query: 771 PSCLLSEQDIRNIKKNMAKFNQQFAHQDEMMSNETKRKLMEHRQ 902 P+ +LS + + ++KN+ +++ QF QD M ++ R L+ H++ Sbjct: 664 PASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQR 707
>sp|Q7VKU3|TOLB_HAEDU TolB protein precursor Length = 426 Score = 42.0 bits (97), Expect = 0.003 Identities = 46/217 (21%), Positives = 90/217 (41%), Gaps = 6/217 (2%) Frame = +3 Query: 3 IDIVGVKDFTWSSKGHLISYWVGEQESTPARIVLISLPSKKEIFAKTLFNVADISLKWSS 182 +D+V V T ++ G+ ++Y + + S PA +VL+ + FNV ++ ++ Sbjct: 99 VDVVVVGQITPANNGYNVAYQLVDTLSNPA-VVLV----------QGSFNVPATQMRQAA 147 Query: 183 QDDFLAVIGERYVKKKTVENQIKYIGLNASLEIY--RVKEKEIPVEKITINEKTQIVAND 356 + + + +I Y+ + + Y RV + + + K +++ + Sbjct: 148 HTVSDQIFEKLTQIRGAFRTKIAYV-VQRGVSAYELRVADYDGFNAFTVVKSKEPLMSPE 206 Query: 357 WEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTILKWSPSGQFIACSSP 536 W NG+K A +TF K I+++DL+ SGQ + +SP G +A +S Sbjct: 207 WSPNGSKLAYVTFENKRPQIVVHDLR-SGQRSVVA--ALKGHNGAPAFSPDGSRLAFASN 263 Query: 537 NSSSIEF----IDGHEGVVLKRVETNNMNDLVWDPTG 635 + I+G + L N + W P G Sbjct: 264 QDGELNIYIANINGGTPIKL-TANVGNNTEPSWSPDG 299
>sp|Q8BHJ5|TBL1R_MOUSE F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like 1X-linked receptor 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 38.5 bits (88), Expect = 0.030 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 2/96 (2%) Frame = +3 Query: 354 DWEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDF-GFSSRMTILKWSPSGQFIA-C 527 DW++N T F ST++ I+ KL GQ + I F G ++ + +KW P+G +A C Sbjct: 315 DWQSNNT------FASCSTDMCIHVCKL-GQDRPIKTFQGHTNEVNAIKWDPTGNLLASC 367 Query: 528 SSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTG 635 S + I + V + + + W PTG Sbjct: 368 SDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTG 403
Score = 32.3 bits (72), Expect = 2.2 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 1/107 (0%) Frame = +3 Query: 333 KTQIVANDWEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTI-LKWSPS 509 K I A W G F + K+T +I+D Q+ F F S + + W + Sbjct: 266 KGPIFALKWNKKGN-FILSAGVDKTT--IIWDAHTGEAKQQ---FPFHSAPALDVDWQSN 319 Query: 510 GQFIACSSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMS 650 F +CS+ + + + + TN +N + WDPTG L S Sbjct: 320 NTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 366
>sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like 1X-linked receptor 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 38.5 bits (88), Expect = 0.030 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 2/96 (2%) Frame = +3 Query: 354 DWEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDF-GFSSRMTILKWSPSGQFIA-C 527 DW++N T F ST++ I+ KL GQ + I F G ++ + +KW P+G +A C Sbjct: 315 DWQSNNT------FASCSTDMCIHVCKL-GQDRPIKTFQGHTNEVNAIKWDPTGNLLASC 367 Query: 528 SSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTG 635 S + I + V + + + W PTG Sbjct: 368 SDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTG 403
Score = 32.3 bits (72), Expect = 2.2 Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 1/107 (0%) Frame = +3 Query: 333 KTQIVANDWEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTI-LKWSPS 509 K I A W G F + K+T +I+D Q+ F F S + + W + Sbjct: 266 KGPIFALKWNKKGN-FILSAGVDKTT--IIWDAHTGEAKQQ---FPFHSAPALDVDWQSN 319 Query: 510 GQFIACSSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMS 650 F +CS+ + + + + TN +N + WDPTG L S Sbjct: 320 NTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 366
>sp|P14197|AAC3_DICDI AAC-rich mRNA clone AAC3 protein Length = 437 Score = 37.4 bits (85), Expect = 0.067 Identities = 38/180 (21%), Positives = 69/180 (38%), Gaps = 17/180 (9%) Frame = +3 Query: 324 INEKTQIVANDWEANGTKFA---------ILTF-------NQKSTNILIYDLKLSGQTQK 455 I K + + W ANGTK A + F N ++N + K + + Sbjct: 121 IGNKKKSTSVAWNANGTKIASSGSDGIVRVWNFDPLGNSNNNNNSNNTSSNSKNNNIKET 180 Query: 456 IMDFGFSSRMTILKWSPSGQFIACSSPNSSSIEFIDGHEGVVLKRVETNNMN-DLVWDPT 632 I G + + WSP + S+ I+ D G + V TN+ N D+ W P Sbjct: 181 IELKGHDGSIEKISWSPKNNDLLASAGTDKVIKIWDVKIGKCIGTVSTNSENIDVRWSPD 240 Query: 633 GRYLMSYRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWRPRPSCLLSEQDIRNIK 812 G+++++ + + +I + + N + L Q+ W +L + NI+ Sbjct: 241 GQFIVA----CTRDDHLALIDLPTIKTLKIYKFNGEELNQVGWDNNGDLILMANSMGNIE 296
>sp|Q9A3H4|TOLB_CAUCR TolB protein precursor Length = 432 Score = 37.0 bits (84), Expect = 0.088 Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 10/170 (5%) Frame = +3 Query: 264 NASLEIYRVKEKEIPVEKITINEKTQIVANDWEANGTKFAILTFNQ-KSTNILIYDLKLS 440 N + +IY + + +IT + + + +GTK + FN + IY + Sbjct: 266 NGNSDIYVMDLRSRATTRITTDPAID-TSPSFSPDGTK---IVFNSDRGGQAQIYVMNTD 321 Query: 441 GQTQKIMDFGFSSRMTILKWSPSGQFIACSSPNSSSIEFIDGHEGVVL-----KRVETNN 605 G + + +G R T WSP G FIA + H GV+ +R+ T + Sbjct: 322 GSGVRRISYG-GGRYTTPVWSPRGDFIAFTKQTGGEF-----HIGVMRADGGDERLLTTS 375 Query: 606 MND--LVWDPTGRYLMSYRLNLINETDGGGVSFHS--ITGRLLMERNYQG 743 D W P GR LM +R E G + ITGR+L Y G Sbjct: 376 YLDEGPTWAPNGRVLMFFR-----EGPSGNPRLWTVDITGRILRPAAYSG 420
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 115,662,649 Number of Sequences: 369166 Number of extensions: 2396200 Number of successful extensions: 6288 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5945 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6252 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10622565690 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)