Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_F22
(887 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P55884|IF39_HUMAN Eukaryotic translation initiation fact... 184 3e-46
sp|Q9C5Z1|IF39_ARATH Eukaryotic translation initiation fact... 140 6e-33
sp|Q10425|IF39_SCHPO Probable eukaryotic translation initia... 139 8e-33
sp|P56821|IF39_TOBAC Eukaryotic translation initiation fact... 137 5e-32
sp|P06103|IF39_YEAST Eukaryotic translation initiation fact... 114 3e-25
sp|Q7VKU3|TOLB_HAEDU TolB protein precursor 42 0.002
sp|Q8BHJ5|TBL1R_MOUSE F-box-like/WD-repeat protein TBL1XR1 ... 39 0.025
sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD-repeat protein TBL1XR1 ... 39 0.025
sp|P14197|AAC3_DICDI AAC-rich mRNA clone AAC3 protein 37 0.056
sp|Q9A3H4|TOLB_CAUCR TolB protein precursor 37 0.074
>sp|P55884|IF39_HUMAN Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta)
(eIF3 p116) (eIF3 p110) (eIF3b)
Length = 814
Score = 184 bits (467), Expect = 3e-46
Identities = 100/297 (33%), Positives = 167/297 (56%), Gaps = 2/297 (0%)
Frame = +3
Query: 3 IDIVGVKDFTWSSKGHLISYWVGEQESTPARIVLISLPSKKEIFAKTLFNVADISLKWSS 182
+ I G+KDF+WS G++I++WV E + PAR+ L+ LP+++EI + LFNV D L W
Sbjct: 462 LKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQK 521
Query: 183 QDDFLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITINEKTQIVANDWE 362
D+L V +R K G+ + EI+R++EK++PV+ + + E I+A WE
Sbjct: 522 NGDYLCVKVDRTPKGTQ--------GVVTNFEIFRMREKQVPVDVVEMKE--TIIAFAWE 571
Query: 363 ANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTILKWSPSGQFIACSSPNS 542
NG+KFA+L ++ Y +K +G+ + I F TI WSP GQF+ + S
Sbjct: 572 PNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIF-WSPQGQFVVLAGLRS 630
Query: 543 --SSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMSYRLNLINETDGGGVSFHSITGR 716
++ F+D + V+ E +D+ WDPTGRY+++ ++ D + GR
Sbjct: 631 MNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVD-NAYWLWTFQGR 689
Query: 717 LLMERNYQGLKQIIWRPRPSCLLSEQDIRNIKKNMAKFNQQFAHQDEMMSNETKRKL 887
LL + N Q++WRPRP LLS++ I+ IKK++ K+++ F +D + ++ ++L
Sbjct: 690 LLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKEL 746
Score = 31.2 bits (69), Expect = 4.0
Identities = 20/77 (25%), Positives = 37/77 (48%)
Frame = +3
Query: 414 ILIYDLKLSGQTQKIMDFGFSSRMTILKWSPSGQFIACSSPNSSSIEFIDGHEGVVLKRV 593
I+I+D+ L+G ++ S+ I KWS G+F A + ++ SI + K +
Sbjct: 404 IIIWDI-LTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSL 462
Query: 594 ETNNMNDLVWDPTGRYL 644
+ + + D W P G +
Sbjct: 463 KISGIKDFSWSPGGNII 479
>sp|Q9C5Z1|IF39_ARATH Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta)
(eIF3 p110) (eIF3b) (p82)
Length = 712
Score = 140 bits (352), Expect = 6e-33
Identities = 85/290 (29%), Positives = 153/290 (52%), Gaps = 7/290 (2%)
Frame = +3
Query: 18 VKDFTWSSKGHLISYWVGEQE--STPARIVLISLPSKKEIFAKTLFNVADISLKWSSQDD 191
V D WS ++S +V EQ + PA++ L+ +PSK E+ K LF+V+D + W S +
Sbjct: 360 VVDICWSPTDSILSLFVPEQGGGNQPAKVALVQIPSKVELRQKNLFSVSDCKMYWQSSGE 419
Query: 192 FLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITI-NEKTQIVANDWEAN 368
+LAV +RY K K + Y G E++R+KE++IP+E + + N+ +I+A WE
Sbjct: 420 YLAVKVDRYTKTK----KSTYSG----FELFRIKERDIPIEVLELDNKNDKIIAFAWEPK 471
Query: 369 GTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGF--SSRMTILKWSPSGQFIACSSPN- 539
G +FA++ +Q ++ Y +K + T ++ + + L WSP+G++I +
Sbjct: 472 GHRFAVIHGDQPRPDVSFYSMKTAQNTGRVSKLATLKAKQANALFWSPTGKYIILAGLKG 531
Query: 540 -SSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMSYRLNLINETDGGGVSFHSITGR 716
+ +EF + E + E D+ WDPTGRY+ + + ++E + G + S G
Sbjct: 532 FNGQLEFFNVDELETMATAEHFMATDIEWDPTGRYVAT-AVTSVHEME-NGFTIWSFNGI 589
Query: 717 LLMERNYQGLKQIIWRPRPSCLLSEQDIRNIKKNMAKFNQQFAHQDEMMS 866
+L Q+ WRPRP L+ + I K + K+++++ +D+ +S
Sbjct: 590 MLYRILKDHFFQLAWRPRPPSFLTAEKEEEIAKTLKKYSKKYEAEDQDVS 639
>sp|Q10425|IF39_SCHPO Probable eukaryotic translation initiation factor 3 90 kDa subunit
(eIF3 p90)
Length = 725
Score = 139 bits (351), Expect = 8e-33
Identities = 106/334 (31%), Positives = 158/334 (47%), Gaps = 39/334 (11%)
Frame = +3
Query: 3 IDIVGVKDFTW---------SSKGHLISYWVGEQESTPARIVLISLPSKKEIFAKTLFNV 155
I I GV++F W SK L++YW E + PAR+ LIS+PSK I K LFNV
Sbjct: 347 IKIDGVQNFEWCPVSDALGRDSKEQLLAYWTPEITNQPARVALISIPSKSTIRTKNLFNV 406
Query: 156 ADISLKWSSQDDFLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITINEK 335
+D L W S D+L V +R+ K K ++LEI+R++EK IPVE + + K
Sbjct: 407 SDCKLYWQSNGDYLCVKVDRHTKTKK--------STFSNLEIFRIREKNIPVEVVDL--K 456
Query: 336 TQIVANDWEANGTKFAILTFNQK-------STNILIYDLKLSGQT----QKIMDFGFSSR 482
++ WE +FAI++ N + TN+ Y + T + I+ F
Sbjct: 457 DVVLNFAWEPKSDRFAIISANDQVLNSTNVKTNLSFYGFEQKKNTPSTFRHIITFD-KKT 515
Query: 483 MTILKWSPSGQFIACSSPNSSS---IEFID------GHEGVVLKRV------ETNNMNDL 617
L +P G+F+ ++ SS+ +EF D E L V E M +L
Sbjct: 516 CNSLFMAPKGRFMVAATLGSSTQYDLEFYDLDFDTEKKEPDALANVQQIGSAEHFGMTEL 575
Query: 618 VWDPTGRYLMS----YRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWRPRPSCLL 785
WDP+GRY+ + +R L N G G LL E KQ IWRPRP L
Sbjct: 576 EWDPSGRYVTTSSTIWRHKLEN-----GYRLCDFRGTLLREEMIGEFKQFIWRPRPPSPL 630
Query: 786 SEQDIRNIKKNMAKFNQQFAHQDEMMSNETKRKL 887
+++D++ I+K + +N+ F +D + R+L
Sbjct: 631 TKEDMKKIRKKLKDYNRLFDEEDIAEQSSANREL 664
>sp|P56821|IF39_TOBAC Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta)
(eIF3 p110) (eIF3b)
Length = 719
Score = 137 bits (344), Expect = 5e-32
Identities = 90/300 (30%), Positives = 152/300 (50%), Gaps = 12/300 (4%)
Frame = +3
Query: 3 IDIVGVKDFTWSSKGHLISYWVGEQESTPARIVLISLPSKKEIFAKTLFNVADISLKWSS 182
I + V DF+WS +++ +V E + PAR+ L+ +PSK+E+ K LF+V+D + W S
Sbjct: 359 IKVENVMDFSWSPADPILALFVPECGNQPARVSLVQIPSKEELRQKNLFSVSDCKMYWQS 418
Query: 183 QDDFLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITI-NEKTQIVANDW 359
D+LAV +RY K K + Y G E++R+KE++IP+E + + N +I A W
Sbjct: 419 NGDYLAVKVDRYTKTK----KSTYTG----FELFRIKERDIPIEVLELDNTNDKIPAFGW 470
Query: 360 EANGTKFAIL-TFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTILK--------WSPSG 512
G+ + +I Y + + T G S++T LK WSP G
Sbjct: 471 GPEGSPICCYPSVTTPRPDIRFYSVPVWALTP-----GLVSKLTTLKGKQANALYWSPGG 525
Query: 513 QFIACSSPN--SSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMSYRLNLINETDGG 686
+F+ + + +EF D E + E D+ WDPTGRY+ + + ++E +
Sbjct: 526 RFLILTGLKGFNGQLEFFDVDELETMASAEHFMATDVEWDPTGRYVAT-SVTSVHEME-N 583
Query: 687 GVSFHSITGRLLMERNYQGLKQIIWRPRPSCLLSEQDIRNIKKNMAKFNQQFAHQDEMMS 866
G + S G+LL Q +WRPRP LS++ I KN+ ++++++ +D+ +S
Sbjct: 584 GFNIWSFNGKLLYRILKDHFFQYLWRPRPPSFLSKEKEEEIAKNLKRYSKKYEAEDQDVS 643
>sp|P06103|IF39_YEAST Eukaryotic translation initiation factor 3 90 kDa subunit (eIF3 p90)
(Cell cycle regulation and translation initiation
protein)
Length = 763
Score = 114 bits (286), Expect = 3e-25
Identities = 83/339 (24%), Positives = 157/339 (46%), Gaps = 48/339 (14%)
Frame = +3
Query: 15 GVKDFTWSSKGH-------------LISYWVGEQESTPARIVLISLPSKKEIFAKTLFNV 155
G++DF+++ +G L++YW E ++ + +P + + L V
Sbjct: 377 GIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQV 436
Query: 156 ADISLKWSSQDDFLAVIGERYVKKKTVENQIKYIGLNASLEIYRVKEKEIPVEKITINEK 335
++++L W +Q +FL ER+ K + ++L+I R+ E++IPVEK+ + K
Sbjct: 437 SNVTLHWQNQAEFLCFNVERHTKSGKTQF--------SNLQICRLTERDIPVEKVEL--K 486
Query: 336 TQIVANDWEANGTKFAILTFNQ--------KSTNILIYDLKLSGQTQKIMDFGFSSRM-- 485
+ WE +G +F ++ ++ + I Y + +T I + +
Sbjct: 487 DSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPK 546
Query: 486 ---TILKWSPSGQFI---ACSSPNS--SSIEFID-GHEGVVLKRVETNN----------- 605
+ WSP+G+F+ A PN S ++F D + G K + NN
Sbjct: 547 TFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGE--KNINDNNDVSASLKDVAH 604
Query: 606 -----MNDLVWDPTGRYLMSYRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWRPR 770
++ WDP+GRY+ ++ +L ++ + G F+ I G L+ E G K WRPR
Sbjct: 605 PTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFN-IAGNLVKEDIIAGFKNFAWRPR 663
Query: 771 PSCLLSEQDIRNIKKNMAKFNQQFAHQDEMMSNETKRKL 887
P+ +LS + + ++KN+ +++ QF QD M ++ R L
Sbjct: 664 PASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDL 702
>sp|Q7VKU3|TOLB_HAEDU TolB protein precursor
Length = 426
Score = 42.0 bits (97), Expect = 0.002
Identities = 46/217 (21%), Positives = 90/217 (41%), Gaps = 6/217 (2%)
Frame = +3
Query: 3 IDIVGVKDFTWSSKGHLISYWVGEQESTPARIVLISLPSKKEIFAKTLFNVADISLKWSS 182
+D+V V T ++ G+ ++Y + + S PA +VL+ + FNV ++ ++
Sbjct: 99 VDVVVVGQITPANNGYNVAYQLVDTLSNPA-VVLV----------QGSFNVPATQMRQAA 147
Query: 183 QDDFLAVIGERYVKKKTVENQIKYIGLNASLEIY--RVKEKEIPVEKITINEKTQIVAND 356
+ + + +I Y+ + + Y RV + + + K +++ +
Sbjct: 148 HTVSDQIFEKLTQIRGAFRTKIAYV-VQRGVSAYELRVADYDGFNAFTVVKSKEPLMSPE 206
Query: 357 WEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTILKWSPSGQFIACSSP 536
W NG+K A +TF K I+++DL+ SGQ + +SP G +A +S
Sbjct: 207 WSPNGSKLAYVTFENKRPQIVVHDLR-SGQRSVVA--ALKGHNGAPAFSPDGSRLAFASN 263
Query: 537 NSSSIEF----IDGHEGVVLKRVETNNMNDLVWDPTG 635
+ I+G + L N + W P G
Sbjct: 264 QDGELNIYIANINGGTPIKL-TANVGNNTEPSWSPDG 299
>sp|Q8BHJ5|TBL1R_MOUSE F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like
1X-linked receptor 1) (Nuclear receptor
corepressor/HDAC3 complex subunit TBLR1) (TBL1-related
protein 1)
Length = 514
Score = 38.5 bits (88), Expect = 0.025
Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Frame = +3
Query: 354 DWEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDF-GFSSRMTILKWSPSGQFIA-C 527
DW++N T F ST++ I+ KL GQ + I F G ++ + +KW P+G +A C
Sbjct: 315 DWQSNNT------FASCSTDMCIHVCKL-GQDRPIKTFQGHTNEVNAIKWDPTGNLLASC 367
Query: 528 SSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTG 635
S + I + V + + + W PTG
Sbjct: 368 SDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTG 403
Score = 32.3 bits (72), Expect = 1.8
Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 1/107 (0%)
Frame = +3
Query: 333 KTQIVANDWEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTI-LKWSPS 509
K I A W G F + K+T +I+D Q+ F F S + + W +
Sbjct: 266 KGPIFALKWNKKGN-FILSAGVDKTT--IIWDAHTGEAKQQ---FPFHSAPALDVDWQSN 319
Query: 510 GQFIACSSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMS 650
F +CS+ + + + + TN +N + WDPTG L S
Sbjct: 320 NTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 366
>sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like
1X-linked receptor 1) (Nuclear receptor
corepressor/HDAC3 complex subunit TBLR1) (TBL1-related
protein 1)
Length = 514
Score = 38.5 bits (88), Expect = 0.025
Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Frame = +3
Query: 354 DWEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDF-GFSSRMTILKWSPSGQFIA-C 527
DW++N T F ST++ I+ KL GQ + I F G ++ + +KW P+G +A C
Sbjct: 315 DWQSNNT------FASCSTDMCIHVCKL-GQDRPIKTFQGHTNEVNAIKWDPTGNLLASC 367
Query: 528 SSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTG 635
S + I + V + + + W PTG
Sbjct: 368 SDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTG 403
Score = 32.3 bits (72), Expect = 1.8
Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 1/107 (0%)
Frame = +3
Query: 333 KTQIVANDWEANGTKFAILTFNQKSTNILIYDLKLSGQTQKIMDFGFSSRMTI-LKWSPS 509
K I A W G F + K+T +I+D Q+ F F S + + W +
Sbjct: 266 KGPIFALKWNKKGN-FILSAGVDKTT--IIWDAHTGEAKQQ---FPFHSAPALDVDWQSN 319
Query: 510 GQFIACSSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMS 650
F +CS+ + + + + TN +N + WDPTG L S
Sbjct: 320 NTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 366
>sp|P14197|AAC3_DICDI AAC-rich mRNA clone AAC3 protein
Length = 437
Score = 37.4 bits (85), Expect = 0.056
Identities = 38/180 (21%), Positives = 69/180 (38%), Gaps = 17/180 (9%)
Frame = +3
Query: 324 INEKTQIVANDWEANGTKFA---------ILTF-------NQKSTNILIYDLKLSGQTQK 455
I K + + W ANGTK A + F N ++N + K + +
Sbjct: 121 IGNKKKSTSVAWNANGTKIASSGSDGIVRVWNFDPLGNSNNNNNSNNTSSNSKNNNIKET 180
Query: 456 IMDFGFSSRMTILKWSPSGQFIACSSPNSSSIEFIDGHEGVVLKRVETNNMN-DLVWDPT 632
I G + + WSP + S+ I+ D G + V TN+ N D+ W P
Sbjct: 181 IELKGHDGSIEKISWSPKNNDLLASAGTDKVIKIWDVKIGKCIGTVSTNSENIDVRWSPD 240
Query: 633 GRYLMSYRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWRPRPSCLLSEQDIRNIK 812
G+++++ + + +I + + N + L Q+ W +L + NI+
Sbjct: 241 GQFIVA----CTRDDHLALIDLPTIKTLKIYKFNGEELNQVGWDNNGDLILMANSMGNIE 296
>sp|Q9A3H4|TOLB_CAUCR TolB protein precursor
Length = 432
Score = 37.0 bits (84), Expect = 0.074
Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 10/170 (5%)
Frame = +3
Query: 264 NASLEIYRVKEKEIPVEKITINEKTQIVANDWEANGTKFAILTFNQ-KSTNILIYDLKLS 440
N + +IY + + +IT + + + +GTK + FN + IY +
Sbjct: 266 NGNSDIYVMDLRSRATTRITTDPAID-TSPSFSPDGTK---IVFNSDRGGQAQIYVMNTD 321
Query: 441 GQTQKIMDFGFSSRMTILKWSPSGQFIACSSPNSSSIEFIDGHEGVVL-----KRVETNN 605
G + + +G R T WSP G FIA + H GV+ +R+ T +
Sbjct: 322 GSGVRRISYG-GGRYTTPVWSPRGDFIAFTKQTGGEF-----HIGVMRADGGDERLLTTS 375
Query: 606 MND--LVWDPTGRYLMSYRLNLINETDGGGVSFHS--ITGRLLMERNYQG 743
D W P GR LM +R E G + ITGR+L Y G
Sbjct: 376 YLDEGPTWAPNGRVLMFFR-----EGPSGNPRLWTVDITGRILRPAAYSG 420
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,297,822
Number of Sequences: 369166
Number of extensions: 2121347
Number of successful extensions: 5701
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5413
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5665
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8886314050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)