Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_I05
(616 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P55884|IF39_HUMAN Eukaryotic translation initiation fact... 85 2e-16
sp|P06103|IF39_YEAST Eukaryotic translation initiation fact... 69 1e-11
sp|P56821|IF39_TOBAC Eukaryotic translation initiation fact... 68 2e-11
sp|Q9C5Z1|IF39_ARATH Eukaryotic translation initiation fact... 61 2e-09
sp|Q10425|IF39_SCHPO Probable eukaryotic translation initia... 58 2e-08
sp|Q9A3H4|TOLB_CAUCR TolB protein precursor 35 0.20
sp|Q5RAC9|APG16_PONPY Autophagy protein 16-like (APG16-like) 33 0.44
sp|Q676U5|APG16_HUMAN Autophagy protein 16-like (APG16-like) 33 0.44
sp|Q8BHJ5|TBL1R_MOUSE F-box-like/WD-repeat protein TBL1XR1 ... 33 0.76
sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD-repeat protein TBL1XR1 ... 33 0.76
>sp|P55884|IF39_HUMAN Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta)
(eIF3 p116) (eIF3 p110) (eIF3b)
Length = 814
Score = 84.7 bits (208), Expect = 2e-16
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 2/158 (1%)
Frame = +3
Query: 27 NILIYDLKLSGQTQKIMDFGFSSRMTILKWSPSGQFIACSSPNS--SSIEFIDGHEGVVL 200
++ Y +K +G+ + I F TI WSP GQF+ + S ++ F+D + V+
Sbjct: 588 SVSFYHVKNNGKIELIKMFDKQQANTIF-WSPQGQFVVLAGLRSMNGALAFVDTSDCTVM 646
Query: 201 KRVETNNMNDLVWDPTGRYLMSYRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWR 380
E +D+ WDPTGRY+++ ++ D + GRLL + N Q++WR
Sbjct: 647 NIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNA-YWLWTFQGRLLQKNNKDRFCQLLWR 705
Query: 381 PRPSCLLSEQDIRNIKKNMAKFNQQFAHQDE*CPMKPS 494
PRP LLS++ I+ IKK++ K+++ F +D K S
Sbjct: 706 PRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKAS 743
Score = 31.6 bits (70), Expect = 1.7
Identities = 21/84 (25%), Positives = 39/84 (46%)
Frame = +3
Query: 9 TRQKSTNILIYDLKLSGQTQKIMDFGFSSRMTILKWSPSGQFIACSSPNSSSIEFIDGHE 188
T+ I+I+D+ L+G ++ S+ I KWS G+F A + ++ SI
Sbjct: 397 TQDDPQAIIIWDI-LTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMG 455
Query: 189 GVVLKRVETNNMNDLVWDPTGRYL 260
+ K ++ + + D W P G +
Sbjct: 456 LLDKKSLKISGIKDFSWSPGGNII 479
>sp|P06103|IF39_YEAST Eukaryotic translation initiation factor 3 90 kDa subunit (eIF3
p90) (Cell cycle regulation and translation initiation
protein)
Length = 763
Score = 68.6 bits (166), Expect = 1e-11
Identities = 43/143 (30%), Positives = 73/143 (51%), Gaps = 22/143 (15%)
Frame = +3
Query: 108 LKWSPSGQFI---ACSSPNS--SSIEFID-GHEGVVLKRVETNN---------------- 221
+ WSP+G+F+ A PN S ++F D + G K + NN
Sbjct: 552 VSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGE--KNINDNNDVSASLKDVAHPTYSA 609
Query: 222 MNDLVWDPTGRYLMSYRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWRPRPSCLL 401
++ WDP+GRY+ ++ +L ++ + G F+ I G L+ E G K WRPRP+ +L
Sbjct: 610 ATNITWDPSGRYVTAWSSSLKHKVEHGYKIFN-IAGNLVKEDIIAGFKNFAWRPRPASIL 668
Query: 402 SEQDIRNIKKNMAKFNQQFAHQD 470
S + + ++KN+ +++ QF QD
Sbjct: 669 SNAERKKVRKNLREWSAQFEEQD 691
>sp|P56821|IF39_TOBAC Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta)
(eIF3 p110) (eIF3b)
Length = 719
Score = 67.8 bits (164), Expect = 2e-11
Identities = 41/140 (29%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Frame = +3
Query: 84 GFSSRMTILK--------WSPSGQFIACSSPN--SSSIEFIDGHEGVVLKRVETNNMNDL 233
G S++T LK WSP G+F+ + + +EF D E + E D+
Sbjct: 503 GLVSKLTTLKGKQANALYWSPGGRFLILTGLKGFNGQLEFFDVDELETMASAEHFMATDV 562
Query: 234 VWDPTGRYLMSYRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWRPRPSCLLSEQD 413
WDPTGRY+ + + ++E + G + S G+LL Q +WRPRP LS++
Sbjct: 563 EWDPTGRYVAT-SVTSVHEMENG-FNIWSFNGKLLYRILKDHFFQYLWRPRPPSFLSKEK 620
Query: 414 IRNIKKNMAKFNQQFAHQDE 473
I KN+ ++++++ +D+
Sbjct: 621 EEEIAKNLKRYSKKYEAEDQ 640
>sp|Q9C5Z1|IF39_ARATH Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta)
(eIF3 p110) (eIF3b) (p82)
Length = 712
Score = 61.2 bits (147), Expect = 2e-09
Identities = 38/157 (24%), Positives = 74/157 (47%), Gaps = 4/157 (2%)
Frame = +3
Query: 15 QKSTNILIYDLKLSGQTQKIMDFGF--SSRMTILKWSPSGQFIACSSPN--SSSIEFIDG 182
Q ++ Y +K + T ++ + + L WSP+G++I + + +EF +
Sbjct: 482 QPRPDVSFYSMKTAQNTGRVSKLATLKAKQANALFWSPTGKYIILAGLKGFNGQLEFFNV 541
Query: 183 HEGVVLKRVETNNMNDLVWDPTGRYLMSYRLNLINETDGGGVSFHSITGRLLMERNYQGL 362
E + E D+ WDPTGRY+ + + ++E + G + S G +L
Sbjct: 542 DELETMATAEHFMATDIEWDPTGRYVAT-AVTSVHEMENG-FTIWSFNGIMLYRILKDHF 599
Query: 363 KQIIWRPRPSCLLSEQDIRNIKKNMAKFNQQFAHQDE 473
Q+ WRPRP L+ + I K + K+++++ +D+
Sbjct: 600 FQLAWRPRPPSFLTAEKEEEIAKTLKKYSKKYEAEDQ 636
>sp|Q10425|IF39_SCHPO Probable eukaryotic translation initiation factor 3 90 kDa subunit
(eIF3 p90)
Length = 725
Score = 58.2 bits (139), Expect = 2e-08
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 19/137 (13%)
Frame = +3
Query: 117 SPSGQFIACSSPNSSS---IEFID------GHEGVVLKRV------ETNNMNDLVWDPTG 251
+P G+F+ ++ SS+ +EF D E L V E M +L WDP+G
Sbjct: 522 APKGRFMVAATLGSSTQYDLEFYDLDFDTEKKEPDALANVQQIGSAEHFGMTELEWDPSG 581
Query: 252 RYLMS----YRLNLINETDGGGVSFHSITGRLLMERNYQGLKQIIWRPRPSCLLSEQDIR 419
RY+ + +R L N G G LL E KQ IWRPRP L+++D++
Sbjct: 582 RYVTTSSTIWRHKLEN-----GYRLCDFRGTLLREEMIGEFKQFIWRPRPPSPLTKEDMK 636
Query: 420 NIKKNMAKFNQQFAHQD 470
I+K + +N+ F +D
Sbjct: 637 KIRKKLKDYNRLFDEED 653
>sp|Q9A3H4|TOLB_CAUCR TolB protein precursor
Length = 432
Score = 34.7 bits (78), Expect = 0.20
Identities = 35/117 (29%), Positives = 47/117 (40%), Gaps = 9/117 (7%)
Frame = +3
Query: 36 IYDLKLSGQTQKIMDFGFSSRMTILKWSPSGQFIACSSPNSSSIEFIDGHEGVVL----- 200
IY + G + + +G R T WSP G FIA + H GV+
Sbjct: 315 IYVMNTDGSGVRRISYG-GGRYTTPVWSPRGDFIAFTKQTGGEF-----HIGVMRADGGD 368
Query: 201 KRVETNNMND--LVWDPTGRYLMSYRLNLINETDGGGVSFHS--ITGRLLMERNYQG 359
+R+ T + D W P GR LM +R E G + ITGR+L Y G
Sbjct: 369 ERLLTTSYLDEGPTWAPNGRVLMFFR-----EGPSGNPRLWTVDITGRILRPAAYSG 420
>sp|Q5RAC9|APG16_PONPY Autophagy protein 16-like (APG16-like)
Length = 607
Score = 33.5 bits (75), Expect = 0.44
Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Frame = +3
Query: 36 IYDLKLSGQTQKIMDFGFS--SRMTILKWSPSGQFIACSSPNSSSIEF--IDGHEGVVLK 203
+ DL+ + Q GF S T + +SP G ++A S S + + G VL
Sbjct: 514 VIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYTWSVLTGKVEKVLS 573
Query: 204 RVETNNMNDLVWDPTGRYLMS 266
+ ++++N + W P+G +++S
Sbjct: 574 KQHSSSINAVAWSPSGLHVVS 594
>sp|Q676U5|APG16_HUMAN Autophagy protein 16-like (APG16-like)
Length = 607
Score = 33.5 bits (75), Expect = 0.44
Identities = 21/81 (25%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Frame = +3
Query: 36 IYDLKLSGQTQKIMDFGFS--SRMTILKWSPSGQFIACSSPNSSSI--EFIDGHEGVVLK 203
+ DL+ + Q GF S T + +SP G ++A S S + G VL
Sbjct: 514 VIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLS 573
Query: 204 RVETNNMNDLVWDPTGRYLMS 266
+ ++++N + W P+G +++S
Sbjct: 574 KQHSSSINAVAWSPSGSHVVS 594
>sp|Q8BHJ5|TBL1R_MOUSE F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like
1X-linked receptor 1) (Nuclear receptor
corepressor/HDAC3 complex subunit TBLR1) (TBL1-related
protein 1)
Length = 514
Score = 32.7 bits (73), Expect = 0.76
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +3
Query: 21 STNILIYDLKLSGQTQKIMDF-GFSSRMTILKWSPSGQFIA-CSSPNSSSIEFIDGHEGV 194
ST++ I+ KL GQ + I F G ++ + +KW P+G +A CS + I + V
Sbjct: 326 STDMCIHVCKL-GQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCV 384
Query: 195 VLKRVETNNMNDLVWDPTG 251
+ + + W PTG
Sbjct: 385 HDLQAHNKEIYTIKWSPTG 403
Score = 30.4 bits (67), Expect = 3.8
Identities = 14/51 (27%), Positives = 23/51 (45%)
Frame = +3
Query: 114 WSPSGQFIACSSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMS 266
W + F +CS+ + + + + TN +N + WDPTG L S
Sbjct: 316 WQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 366
>sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like
1X-linked receptor 1) (Nuclear receptor
corepressor/HDAC3 complex subunit TBLR1) (TBL1-related
protein 1)
Length = 514
Score = 32.7 bits (73), Expect = 0.76
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +3
Query: 21 STNILIYDLKLSGQTQKIMDF-GFSSRMTILKWSPSGQFIA-CSSPNSSSIEFIDGHEGV 194
ST++ I+ KL GQ + I F G ++ + +KW P+G +A CS + I + V
Sbjct: 326 STDMCIHVCKL-GQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCV 384
Query: 195 VLKRVETNNMNDLVWDPTG 251
+ + + W PTG
Sbjct: 385 HDLQAHNKEIYTIKWSPTG 403
Score = 30.4 bits (67), Expect = 3.8
Identities = 14/51 (27%), Positives = 23/51 (45%)
Frame = +3
Query: 114 WSPSGQFIACSSPNSSSIEFIDGHEGVVLKRVETNNMNDLVWDPTGRYLMS 266
W + F +CS+ + + + + TN +N + WDPTG L S
Sbjct: 316 WQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 366
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,542,705
Number of Sequences: 369166
Number of extensions: 1431524
Number of successful extensions: 3568
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3425
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3550
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4846822695
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)