Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00009 (830 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 99 2e-20 sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 98 2e-20 sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 97 5e-20 sp|Q8WTR7|ZN473_HUMAN Zinc finger protein 473 (Zinc finger ... 42 0.002 sp|Q6ZMZ0|IBR3_HUMAN IBR domain containing protein 3 42 0.002 sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body prote... 39 0.013 sp|Q9NV58|RNF19_HUMAN RING finger protein 19 (Dorfin) (Doub... 39 0.013 sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 39 0.023 sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 37 0.051 sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-betwe... 37 0.067
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B virus X-associated protein 4) (HBV-associated factor 4) (RING finger protein 54) Length = 500 Score = 98.6 bits (244), Expect = 2e-20 Identities = 57/221 (25%), Positives = 104/221 (47%), Gaps = 13/221 (5%) Frame = +1 Query: 103 VQYDCKQCSLFN---------CVRCKAPHKWKSCGQYKSLGSVEAQKLCQDEFQRARAEL 255 V + C C+ N C R + P ++ Y+ A+ ++E R + Sbjct: 185 VGWQCPGCTFINKPTRPGCEMCCRAR-PEAYQVPASYQPDEEERARLAGEEEALRQYQQR 243 Query: 256 NKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV 435 ++Q N + V D L+ N+E +C +C +++ + + LR+C H CR+C++ + Sbjct: 244 KQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTI 303 Query: 436 ISFPDIPISCP-INN---CGLLMEDRESRELLNPMECSLFERKSLYKAKSKLQKSDHCRK 603 + + +SCP I+N C + +RE + LL P + F + A+++ S HC+ Sbjct: 304 RNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKT 363 Query: 604 ENCEYFIDVGKNLEQWTCVNCKSNNCLKCNAIHNNQTCTEY 726 +C+ + ++ ++TC C NCL C AIH C EY Sbjct: 364 PDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEY 404
Score = 43.9 bits (102), Expect = 5e-04 Identities = 26/116 (22%), Positives = 49/116 (42%) Frame = +1 Query: 49 HECLLTECKMIIMFSDLNVQYDCKQCSLFNCVRCKAPHKWKSCGQYKSLGSVEAQKLCQD 228 + C +CK F D ++ C C NC+ CKA H+ +C +Y+ +D Sbjct: 359 YHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQ-----------ED 407 Query: 229 EFQRARAELNKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQC 396 RA+ ++ RQ++ + +++ E +C C ++ K G +C Sbjct: 408 LALRAQNDVAARQTTEMLK--------VMLQQGEAMRCPQCQIVVQKKDGCDWIRC 455
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein interacting with PKC) (Protein kinase C-binding protein beta-15) Length = 498 Score = 98.2 bits (243), Expect = 2e-20 Identities = 57/221 (25%), Positives = 104/221 (47%), Gaps = 13/221 (5%) Frame = +1 Query: 103 VQYDCKQCSLFN---------CVRCKAPHKWKSCGQYKSLGSVEAQKLCQDEFQRARAEL 255 V + C C+ N C R + P ++ Y+ A+ ++E R + Sbjct: 183 VGWQCPGCTFINKPTRPGCEMCCRAR-PEAYQIPASYQPDEEERARLAGEEEALRQYEQR 241 Query: 256 NKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV 435 ++Q N + V + L+ N+E +C +C +++ + + LR+C H CR+C++ + Sbjct: 242 KQQQQEGNYLQHVQLEQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTI 301 Query: 436 ISFPDIPISCP-INN---CGLLMEDRESRELLNPMECSLFERKSLYKAKSKLQKSDHCRK 603 + + +SCP I+N C + +RE R LL+P + F + A+++ S HC+ Sbjct: 302 RNSQEAEVSCPFIDNTYSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKT 361 Query: 604 ENCEYFIDVGKNLEQWTCVNCKSNNCLKCNAIHNNQTCTEY 726 +C + ++ ++TC C NCL C AIH C EY Sbjct: 362 PDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHERMNCREY 402
Score = 43.1 bits (100), Expect = 0.001 Identities = 25/116 (21%), Positives = 48/116 (41%) Frame = +1 Query: 49 HECLLTECKMIIMFSDLNVQYDCKQCSLFNCVRCKAPHKWKSCGQYKSLGSVEAQKLCQD 228 + C +C+ F D ++ C C+ NC+ CKA H+ +C +Y+ D Sbjct: 357 YHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHERMNCREYQ-----------DD 405 Query: 229 EFQRARAELNKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQC 396 RAR ++ +Q++ + +++ E C C ++ K G +C Sbjct: 406 LAHRARNDVAAQQTTEMLR--------VMLQQGEAMYCPQCRIVVQKKDGCDWIRC 453
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3 (UbcM4-interacting protein 28) Length = 498 Score = 97.1 bits (240), Expect = 5e-20 Identities = 54/221 (24%), Positives = 103/221 (46%), Gaps = 13/221 (5%) Frame = +1 Query: 103 VQYDCKQCSLFN---------CVRCKAPHKWKSCGQYKSLGSVEAQKLCQDEFQRARAEL 255 V + C C+ N C R + P ++ Y+ A+ ++E R + Sbjct: 183 VGWQCPGCTFINKPTRPGCEMCCRAR-PETYQIPASYQPDEEERARLAGEEEALRQYQQR 241 Query: 256 NKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV 435 ++Q N + V + L+ N+E +C +C +++ + + LR+C H CR+C++ + Sbjct: 242 KQQQQEGNYLQHVQLEQRSLVLNTEPTECPVCYSVLAPGEAVVLRECLHTFCRECLQGTI 301 Query: 436 ISFPDIPISCPI----NNCGLLMEDRESRELLNPMECSLFERKSLYKAKSKLQKSDHCRK 603 + + ++CP +C + +RE R LL+P + F + A+++ S HC+ Sbjct: 302 RNSQEAEVACPFIDSTYSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKT 361 Query: 604 ENCEYFIDVGKNLEQWTCVNCKSNNCLKCNAIHNNQTCTEY 726 +C + ++ ++TC C NCL C AIH + C EY Sbjct: 362 PDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHEHMNCREY 402
Score = 43.1 bits (100), Expect = 0.001 Identities = 26/116 (22%), Positives = 46/116 (39%) Frame = +1 Query: 49 HECLLTECKMIIMFSDLNVQYDCKQCSLFNCVRCKAPHKWKSCGQYKSLGSVEAQKLCQD 228 + C +C+ F D ++ C C+ NC+ CKA H+ +C +Y+ ++ AQ D Sbjct: 357 YHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHEHMNCREYQDDLALRAQ---ND 413 Query: 229 EFQRARAELNKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQC 396 R E+ K +++ E C C ++ K G +C Sbjct: 414 VAARQTTEMLK----------------VMLQQGEAMHCPQCRIVVQKKDGCDWIRC 453
>sp|Q8WTR7|ZN473_HUMAN Zinc finger protein 473 (Zinc finger protein 100 homolog) (Zfp-100) Length = 871 Score = 42.4 bits (98), Expect = 0.002 Identities = 46/241 (19%), Positives = 92/241 (38%), Gaps = 30/241 (12%) Frame = +1 Query: 106 QYDCKQC-SLFNC----VRCKAPHKWKSCGQYKSLGSVEAQKLCQDEFQRARA-----EL 255 +Y+C +C + FN ++ + H K+ + + G + E Q A + Sbjct: 346 RYECSKCQATFNLRKHLIQHQKTHAAKTTSECQECGKIFRHSSLLIEHQALHAGEEPYKC 405 Query: 256 NKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQCFH-----NVCRDC 420 N+R S R H + + ++C C +H + + H + C++C Sbjct: 406 NER-GKSFRHNSTLKIHQRVHSGEKPYKCSECGKAFHRHTHLNEHRRIHTGYRPHKCQEC 464 Query: 421 IKQ----------HVISFPDIPISCP-----INNCGLLMEDRESRELLNPMECSLFERKS 555 ++ I + P SC ++ L++ ++ + P EC + Sbjct: 465 VRSFSRPSHLMRHQAIHTAEKPYSCAECKETFSDNNRLVQHQKMHTVKTPYECQECGERF 524 Query: 556 LYKAKSKLQKSDHCRKENCEYFIDVGKNLEQWTCVNCKSNNCLKCNAIHNNQTCTEYIKS 735 + + K +S H R++ + F GK L+Q + C KCN +C++Y+ Sbjct: 525 ICGSTLKCHESVHAREK--QGFFVSGKILDQNPE---QKEKCFKCNKCEKTFSCSKYLTQ 579 Query: 736 H 738 H Sbjct: 580 H 580
>sp|Q6ZMZ0|IBR3_HUMAN IBR domain containing protein 3 Length = 486 Score = 42.4 bits (98), Expect = 0.002 Identities = 35/120 (29%), Positives = 52/120 (43%), Gaps = 9/120 (7%) Frame = +1 Query: 385 LRQCFHNVCRDCIKQHV---ISFPDIPISCPINNCGLLMEDRESRELL-NPMECSLFERK 552 L C H CRDC++ ++ IS +PISCP C + + R LL +P +E Sbjct: 33 LLSCPHRSCRDCLRHYLRLEISESRVPISCP--ECSERLNPHDIRLLLADPPLMHKYEEF 90 Query: 553 SLYKAKSKLQKSDHCRKENCEYFIDV--GKNLEQWTC--VNCKSNNCLKCNAI-HNNQTC 717 L + + C +C Y + + + TC C++ C C I H NQTC Sbjct: 91 MLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYHCKQIWHPNQTC 150
>sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117) Length = 840 Score = 39.3 bits (90), Expect = 0.013 Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 11/141 (7%) Frame = +1 Query: 328 EVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV---ISFPDIPISCPINNCGLLMED 498 + +C +C K + + C H C DC++Q++ IS + ISCP C Sbjct: 128 DFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCP--ECTERFNP 185 Query: 499 RESRELLNPMECSLFERKSLYKAKSKLQKSDHCR---KENCEYFIDV--GKNLEQWTC-- 657 + R +L+ + L E+ + + L CR +C Y + + + TC Sbjct: 186 HDIRLILS--DDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGR 243 Query: 658 VNCKSNNCLKCNAI-HNNQTC 717 C + C C I H NQTC Sbjct: 244 EGCGTEFCYHCKQIWHPNQTC 264
>sp|Q9NV58|RNF19_HUMAN RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein) Length = 838 Score = 39.3 bits (90), Expect = 0.013 Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 11/141 (7%) Frame = +1 Query: 328 EVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV---ISFPDIPISCPINNCGLLMED 498 + +C +C K + + C H C DC++Q++ IS + ISCP C Sbjct: 128 DFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCP--ECTERFNP 185 Query: 499 RESRELLNPMECSLFERKSLYKAKSKLQKSDHCR---KENCEYFIDV--GKNLEQWTC-- 657 + R +L+ + L E+ + + L CR +C Y + + + TC Sbjct: 186 HDIRLILS--DDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGR 243 Query: 658 VNCKSNNCLKCNAI-HNNQTC 717 C + C C I H NQTC Sbjct: 244 EGCGTEFCYHCKQIWHPNQTC 264
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein) Length = 493 Score = 38.5 bits (88), Expect = 0.023 Identities = 46/179 (25%), Positives = 71/179 (39%), Gaps = 12/179 (6%) Frame = +1 Query: 214 KLCQDEFQRARAELNKRQSSSNRQRLVAA----DHSILIPNSEV-FQCDICNTIIGKHKG 378 KL F +E+ R S++ Q LV A + S +P S C +C + K Sbjct: 92 KLILVNFHWQVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENL 151 Query: 379 ITLRQCFHNVCRDCIKQH----VISFPDIPISCPINNCGLLMEDRESRELLNPMECSLFE 546 ++L C H CR C +QH V + +SC +C L + LL E Sbjct: 152 LSLA-CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKY 210 Query: 547 RKSLYK--AKSKLQKSDHCRKENCEYFIDVGK-NLEQWTCVNCKSNNCLKCNAIHNNQT 714 R+ L++ +S Q C +C I V + + C C C KC +++ T Sbjct: 211 RRYLFRDYVESHYQ-LQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPT 268
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48) Length = 492 Score = 37.4 bits (85), Expect = 0.051 Identities = 46/179 (25%), Positives = 71/179 (39%), Gaps = 12/179 (6%) Frame = +1 Query: 214 KLCQDEFQRARAELNKRQSSSNRQRLVAA----DHSILIPNSEV-FQCDICNTIIGKHKG 378 KL F +E+ R S++ Q LV A + S +P + C +C + K Sbjct: 91 KLILVNFHWQVSEILDRYRSNSAQLLVEARVQPNPSKHVPTAHPPHHCAVCMQFVRKENL 150 Query: 379 ITLRQCFHNVCRDCIKQH----VISFPDIPISCPINNCGLLMEDRESRELLNPMECSLFE 546 ++L C H CR C +QH V + ISC +C L + LL E Sbjct: 151 LSLA-CQHQFCRSCWEQHCSVLVKDGVGVGISCMAQDCPLRTPEDFVFPLLPNEELRDKY 209 Query: 547 RKSLYK--AKSKLQKSDHCRKENCEYFIDVGK-NLEQWTCVNCKSNNCLKCNAIHNNQT 714 R+ L++ +S Q C +C I V + + C C C KC +++ T Sbjct: 210 RRYLFRDYVESHFQ-LQLCPGADCPMVIRVQEPRARRVQCNRCSEVFCFKCRQMYHAPT 267
>sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-between-RING-finger ubiquitin-associated domain protein) Length = 1072 Score = 37.0 bits (84), Expect = 0.067 Identities = 36/150 (24%), Positives = 60/150 (40%), Gaps = 20/150 (13%) Frame = +1 Query: 337 QCDICNTIIGKHKGITLRQCFHNVCRDCIKQH-VISFPDIPIS---CPINNCGLLMEDR- 501 +C +C + ++ L C +C DC +QH I+ + I+ CP L +D Sbjct: 698 ECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQ 757 Query: 502 ----------ESRELLNPMECSLFERKSLYKAKSKLQKSDHCRKENCEY-FIDVGKNLEQ 648 + RE L P +LF +K + K C + C + FI + LE Sbjct: 758 LLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQ--CSFGFIYEREQLEA 815 Query: 649 WTCVNCKSNNCLKC----NAIHNNQTCTEY 726 TC C C++C H ++C ++ Sbjct: 816 -TCPQCHQTFCVRCKRQWEEQHRGRSCEDF 844
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 94,696,434 Number of Sequences: 369166 Number of extensions: 1958861 Number of successful extensions: 5509 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5190 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5494 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8052550455 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)