Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_C20
(830 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 99 2e-20
sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 98 2e-20
sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 97 5e-20
sp|Q8WTR7|ZN473_HUMAN Zinc finger protein 473 (Zinc finger ... 42 0.002
sp|Q6ZMZ0|IBR3_HUMAN IBR domain containing protein 3 42 0.002
sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body prote... 39 0.013
sp|Q9NV58|RNF19_HUMAN RING finger protein 19 (Dorfin) (Doub... 39 0.013
sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 39 0.023
sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 37 0.051
sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-betwe... 37 0.067
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B
virus X-associated protein 4) (HBV-associated factor 4)
(RING finger protein 54)
Length = 500
Score = 98.6 bits (244), Expect = 2e-20
Identities = 57/221 (25%), Positives = 104/221 (47%), Gaps = 13/221 (5%)
Frame = +1
Query: 103 VQYDCKQCSLFN---------CVRCKAPHKWKSCGQYKSLGSVEAQKLCQDEFQRARAEL 255
V + C C+ N C R + P ++ Y+ A+ ++E R +
Sbjct: 185 VGWQCPGCTFINKPTRPGCEMCCRAR-PEAYQVPASYQPDEEERARLAGEEEALRQYQQR 243
Query: 256 NKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV 435
++Q N + V D L+ N+E +C +C +++ + + LR+C H CR+C++ +
Sbjct: 244 KQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTI 303
Query: 436 ISFPDIPISCP-INN---CGLLMEDRESRELLNPMECSLFERKSLYKAKSKLQKSDHCRK 603
+ + +SCP I+N C + +RE + LL P + F + A+++ S HC+
Sbjct: 304 RNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKT 363
Query: 604 ENCEYFIDVGKNLEQWTCVNCKSNNCLKCNAIHNNQTCTEY 726
+C+ + ++ ++TC C NCL C AIH C EY
Sbjct: 364 PDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEY 404
Score = 43.9 bits (102), Expect = 5e-04
Identities = 26/116 (22%), Positives = 49/116 (42%)
Frame = +1
Query: 49 HECLLTECKMIIMFSDLNVQYDCKQCSLFNCVRCKAPHKWKSCGQYKSLGSVEAQKLCQD 228
+ C +CK F D ++ C C NC+ CKA H+ +C +Y+ +D
Sbjct: 359 YHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQ-----------ED 407
Query: 229 EFQRARAELNKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQC 396
RA+ ++ RQ++ + +++ E +C C ++ K G +C
Sbjct: 408 LALRAQNDVAARQTTEMLK--------VMLQQGEAMRCPQCQIVVQKKDGCDWIRC 455
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein
interacting with PKC) (Protein kinase C-binding protein
beta-15)
Length = 498
Score = 98.2 bits (243), Expect = 2e-20
Identities = 57/221 (25%), Positives = 104/221 (47%), Gaps = 13/221 (5%)
Frame = +1
Query: 103 VQYDCKQCSLFN---------CVRCKAPHKWKSCGQYKSLGSVEAQKLCQDEFQRARAEL 255
V + C C+ N C R + P ++ Y+ A+ ++E R +
Sbjct: 183 VGWQCPGCTFINKPTRPGCEMCCRAR-PEAYQIPASYQPDEEERARLAGEEEALRQYEQR 241
Query: 256 NKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV 435
++Q N + V + L+ N+E +C +C +++ + + LR+C H CR+C++ +
Sbjct: 242 KQQQQEGNYLQHVQLEQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTI 301
Query: 436 ISFPDIPISCP-INN---CGLLMEDRESRELLNPMECSLFERKSLYKAKSKLQKSDHCRK 603
+ + +SCP I+N C + +RE R LL+P + F + A+++ S HC+
Sbjct: 302 RNSQEAEVSCPFIDNTYSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKT 361
Query: 604 ENCEYFIDVGKNLEQWTCVNCKSNNCLKCNAIHNNQTCTEY 726
+C + ++ ++TC C NCL C AIH C EY
Sbjct: 362 PDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHERMNCREY 402
Score = 43.1 bits (100), Expect = 0.001
Identities = 25/116 (21%), Positives = 48/116 (41%)
Frame = +1
Query: 49 HECLLTECKMIIMFSDLNVQYDCKQCSLFNCVRCKAPHKWKSCGQYKSLGSVEAQKLCQD 228
+ C +C+ F D ++ C C+ NC+ CKA H+ +C +Y+ D
Sbjct: 357 YHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHERMNCREYQ-----------DD 405
Query: 229 EFQRARAELNKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQC 396
RAR ++ +Q++ + +++ E C C ++ K G +C
Sbjct: 406 LAHRARNDVAAQQTTEMLR--------VMLQQGEAMYCPQCRIVVQKKDGCDWIRC 453
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3
(UbcM4-interacting protein 28)
Length = 498
Score = 97.1 bits (240), Expect = 5e-20
Identities = 54/221 (24%), Positives = 103/221 (46%), Gaps = 13/221 (5%)
Frame = +1
Query: 103 VQYDCKQCSLFN---------CVRCKAPHKWKSCGQYKSLGSVEAQKLCQDEFQRARAEL 255
V + C C+ N C R + P ++ Y+ A+ ++E R +
Sbjct: 183 VGWQCPGCTFINKPTRPGCEMCCRAR-PETYQIPASYQPDEEERARLAGEEEALRQYQQR 241
Query: 256 NKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV 435
++Q N + V + L+ N+E +C +C +++ + + LR+C H CR+C++ +
Sbjct: 242 KQQQQEGNYLQHVQLEQRSLVLNTEPTECPVCYSVLAPGEAVVLRECLHTFCRECLQGTI 301
Query: 436 ISFPDIPISCPI----NNCGLLMEDRESRELLNPMECSLFERKSLYKAKSKLQKSDHCRK 603
+ + ++CP +C + +RE R LL+P + F + A+++ S HC+
Sbjct: 302 RNSQEAEVACPFIDSTYSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKT 361
Query: 604 ENCEYFIDVGKNLEQWTCVNCKSNNCLKCNAIHNNQTCTEY 726
+C + ++ ++TC C NCL C AIH + C EY
Sbjct: 362 PDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHEHMNCREY 402
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/116 (22%), Positives = 46/116 (39%)
Frame = +1
Query: 49 HECLLTECKMIIMFSDLNVQYDCKQCSLFNCVRCKAPHKWKSCGQYKSLGSVEAQKLCQD 228
+ C +C+ F D ++ C C+ NC+ CKA H+ +C +Y+ ++ AQ D
Sbjct: 357 YHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHEHMNCREYQDDLALRAQ---ND 413
Query: 229 EFQRARAELNKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQC 396
R E+ K +++ E C C ++ K G +C
Sbjct: 414 VAARQTTEMLK----------------VMLQQGEAMHCPQCRIVVQKKDGCDWIRC 453
>sp|Q8WTR7|ZN473_HUMAN Zinc finger protein 473 (Zinc finger protein 100 homolog) (Zfp-100)
Length = 871
Score = 42.4 bits (98), Expect = 0.002
Identities = 46/241 (19%), Positives = 92/241 (38%), Gaps = 30/241 (12%)
Frame = +1
Query: 106 QYDCKQC-SLFNC----VRCKAPHKWKSCGQYKSLGSVEAQKLCQDEFQRARA-----EL 255
+Y+C +C + FN ++ + H K+ + + G + E Q A +
Sbjct: 346 RYECSKCQATFNLRKHLIQHQKTHAAKTTSECQECGKIFRHSSLLIEHQALHAGEEPYKC 405
Query: 256 NKRQSSSNRQRLVAADHSILIPNSEVFQCDICNTIIGKHKGITLRQCFH-----NVCRDC 420
N+R S R H + + ++C C +H + + H + C++C
Sbjct: 406 NER-GKSFRHNSTLKIHQRVHSGEKPYKCSECGKAFHRHTHLNEHRRIHTGYRPHKCQEC 464
Query: 421 IKQ----------HVISFPDIPISCP-----INNCGLLMEDRESRELLNPMECSLFERKS 555
++ I + P SC ++ L++ ++ + P EC +
Sbjct: 465 VRSFSRPSHLMRHQAIHTAEKPYSCAECKETFSDNNRLVQHQKMHTVKTPYECQECGERF 524
Query: 556 LYKAKSKLQKSDHCRKENCEYFIDVGKNLEQWTCVNCKSNNCLKCNAIHNNQTCTEYIKS 735
+ + K +S H R++ + F GK L+Q + C KCN +C++Y+
Sbjct: 525 ICGSTLKCHESVHAREK--QGFFVSGKILDQNPE---QKEKCFKCNKCEKTFSCSKYLTQ 579
Query: 736 H 738
H
Sbjct: 580 H 580
>sp|Q6ZMZ0|IBR3_HUMAN IBR domain containing protein 3
Length = 486
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/120 (29%), Positives = 52/120 (43%), Gaps = 9/120 (7%)
Frame = +1
Query: 385 LRQCFHNVCRDCIKQHV---ISFPDIPISCPINNCGLLMEDRESRELL-NPMECSLFERK 552
L C H CRDC++ ++ IS +PISCP C + + R LL +P +E
Sbjct: 33 LLSCPHRSCRDCLRHYLRLEISESRVPISCP--ECSERLNPHDIRLLLADPPLMHKYEEF 90
Query: 553 SLYKAKSKLQKSDHCRKENCEYFIDV--GKNLEQWTC--VNCKSNNCLKCNAI-HNNQTC 717
L + + C +C Y + + + TC C++ C C I H NQTC
Sbjct: 91 MLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYHCKQIWHPNQTC 150
>sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis
expressed protein GEG-154) (UBCM4-interacting protein
117) (UIP117)
Length = 840
Score = 39.3 bits (90), Expect = 0.013
Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 11/141 (7%)
Frame = +1
Query: 328 EVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV---ISFPDIPISCPINNCGLLMED 498
+ +C +C K + + C H C DC++Q++ IS + ISCP C
Sbjct: 128 DFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCP--ECTERFNP 185
Query: 499 RESRELLNPMECSLFERKSLYKAKSKLQKSDHCR---KENCEYFIDV--GKNLEQWTC-- 657
+ R +L+ + L E+ + + L CR +C Y + + + TC
Sbjct: 186 HDIRLILS--DDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGR 243
Query: 658 VNCKSNNCLKCNAI-HNNQTC 717
C + C C I H NQTC
Sbjct: 244 EGCGTEFCYHCKQIWHPNQTC 264
>sp|Q9NV58|RNF19_HUMAN RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38
protein)
Length = 838
Score = 39.3 bits (90), Expect = 0.013
Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 11/141 (7%)
Frame = +1
Query: 328 EVFQCDICNTIIGKHKGITLRQCFHNVCRDCIKQHV---ISFPDIPISCPINNCGLLMED 498
+ +C +C K + + C H C DC++Q++ IS + ISCP C
Sbjct: 128 DFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCP--ECTERFNP 185
Query: 499 RESRELLNPMECSLFERKSLYKAKSKLQKSDHCR---KENCEYFIDV--GKNLEQWTC-- 657
+ R +L+ + L E+ + + L CR +C Y + + + TC
Sbjct: 186 HDIRLILS--DDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGR 243
Query: 658 VNCKSNNCLKCNAI-HNNQTC 717
C + C C I H NQTC
Sbjct: 244 EGCGTEFCYHCKQIWHPNQTC 264
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
Length = 493
Score = 38.5 bits (88), Expect = 0.023
Identities = 46/179 (25%), Positives = 71/179 (39%), Gaps = 12/179 (6%)
Frame = +1
Query: 214 KLCQDEFQRARAELNKRQSSSNRQRLVAA----DHSILIPNSEV-FQCDICNTIIGKHKG 378
KL F +E+ R S++ Q LV A + S +P S C +C + K
Sbjct: 92 KLILVNFHWQVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENL 151
Query: 379 ITLRQCFHNVCRDCIKQH----VISFPDIPISCPINNCGLLMEDRESRELLNPMECSLFE 546
++L C H CR C +QH V + +SC +C L + LL E
Sbjct: 152 LSLA-CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKY 210
Query: 547 RKSLYK--AKSKLQKSDHCRKENCEYFIDVGK-NLEQWTCVNCKSNNCLKCNAIHNNQT 714
R+ L++ +S Q C +C I V + + C C C KC +++ T
Sbjct: 211 RRYLFRDYVESHYQ-LQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPT 268
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
(UbcM4-interacting protein 48)
Length = 492
Score = 37.4 bits (85), Expect = 0.051
Identities = 46/179 (25%), Positives = 71/179 (39%), Gaps = 12/179 (6%)
Frame = +1
Query: 214 KLCQDEFQRARAELNKRQSSSNRQRLVAA----DHSILIPNSEV-FQCDICNTIIGKHKG 378
KL F +E+ R S++ Q LV A + S +P + C +C + K
Sbjct: 91 KLILVNFHWQVSEILDRYRSNSAQLLVEARVQPNPSKHVPTAHPPHHCAVCMQFVRKENL 150
Query: 379 ITLRQCFHNVCRDCIKQH----VISFPDIPISCPINNCGLLMEDRESRELLNPMECSLFE 546
++L C H CR C +QH V + ISC +C L + LL E
Sbjct: 151 LSLA-CQHQFCRSCWEQHCSVLVKDGVGVGISCMAQDCPLRTPEDFVFPLLPNEELRDKY 209
Query: 547 RKSLYK--AKSKLQKSDHCRKENCEYFIDVGK-NLEQWTCVNCKSNNCLKCNAIHNNQT 714
R+ L++ +S Q C +C I V + + C C C KC +++ T
Sbjct: 210 RRYLFRDYVESHFQ-LQLCPGADCPMVIRVQEPRARRVQCNRCSEVFCFKCRQMYHAPT 267
>sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-between-RING-finger
ubiquitin-associated domain protein)
Length = 1072
Score = 37.0 bits (84), Expect = 0.067
Identities = 36/150 (24%), Positives = 60/150 (40%), Gaps = 20/150 (13%)
Frame = +1
Query: 337 QCDICNTIIGKHKGITLRQCFHNVCRDCIKQH-VISFPDIPIS---CPINNCGLLMEDR- 501
+C +C + ++ L C +C DC +QH I+ + I+ CP L +D
Sbjct: 698 ECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQ 757
Query: 502 ----------ESRELLNPMECSLFERKSLYKAKSKLQKSDHCRKENCEY-FIDVGKNLEQ 648
+ RE L P +LF +K + K C + C + FI + LE
Sbjct: 758 LLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQ--CSFGFIYEREQLEA 815
Query: 649 WTCVNCKSNNCLKC----NAIHNNQTCTEY 726
TC C C++C H ++C ++
Sbjct: 816 -TCPQCHQTFCVRCKRQWEEQHRGRSCEDF 844
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,696,434
Number of Sequences: 369166
Number of extensions: 1958861
Number of successful extensions: 5509
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5190
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5494
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8052550455
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)