Planaria EST Database

DrC_00002

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00002
         (986 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9NNW7|TRXR2_HUMAN  Thioredoxin reductase 2, mitochondria...   240   4e-63
sp|Q9JLT4|TRXR2_MOUSE  Thioredoxin reductase 2, mitochondria...   240   5e-63
sp|Q9Z0J5|TRXR2_RAT  Thioredoxin reductase 2, mitochondrial ...   239   1e-62
sp|Q9N2I8|TRXR2_BOVIN  Thioredoxin reductase 2, mitochondria...   226   1e-58
sp|O89049|TRXR1_RAT  Thioredoxin reductase 1, cytoplasmic (T...   219   9e-57
sp|Q9JMH6|TRXR1_MOUSE  Thioredoxin reductase 1, cytoplasmic ...   219   9e-57
sp|O62768|TRXR1_BOVIN  Thioredoxin reductase 1, cytoplasmic ...   219   9e-57
sp|P91938|TRXR1_DROME  Thioredoxin reductase 1, mitochondria...   218   2e-56
sp|Q16881|TRXR1_HUMAN  Thioredoxin reductase 1, cytoplasmic ...   216   6e-56
sp|Q9MYY8|TRXR1_PIG  Thioredoxin reductase 1, cytoplasmic (T...   216   6e-56

>sp|Q9NNW7|TRXR2_HUMAN Thioredoxin reductase 2, mitochondrial precursor (TR3) (TR-beta)
            (Selenoprotein Z) (SelZ)
          Length = 524

 Score =  240 bits (613), Expect = 4e-63
 Identities = 127/247 (51%), Positives = 168/247 (68%), Gaps = 1/247 (0%)
 Frame = +3

Query: 51   PIEVIQGDSGKFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPNTKK 230
            P  V +   G+ +V W+      E +  FDTVL+AIGR P T  LNL  A V   P+T+K
Sbjct: 281  PSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQK 340

Query: 231  IVSGSKSKSADMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMNYEM 410
            I+  S+      E TS P+IYAIGDV++G  ELTP+AI AGRLL +RLF   +  M+Y+ 
Sbjct: 341  ILVDSR------EATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDN 394

Query: 411  ISTTVFTPLEYACVGMTEEEAFSKLGDKNVEVYHCYFKPLEIVSMGQQPS-CYMKMICDV 587
            + TTVFTPLEY CVG++EEEA ++ G ++VEVYH ++KPLE    G+  S CY+KM+C  
Sbjct: 395  VPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLR 454

Query: 588  SKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITKRSN 767
               + V+GLH LG NAGE+ QGFA+ IK G ++ Q+  TVGIHPT +EEVVKL I+KRS 
Sbjct: 455  EPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 514

Query: 768  IDPHLTG 788
            +DP +TG
Sbjct: 515  LDPTVTG 521

>sp|Q9JLT4|TRXR2_MOUSE Thioredoxin reductase 2, mitochondrial precursor (TR3)
          Length = 524

 Score =  240 bits (612), Expect = 5e-63
 Identities = 125/247 (50%), Positives = 168/247 (68%), Gaps = 1/247 (0%)
 Frame = +3

Query: 51   PIEVIQGDSGKFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPNTKK 230
            P  + +  + + +V W+   +  E +  FDTVL+AIGR P T  LNL  A +S +P  +K
Sbjct: 281  PSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPKNQK 340

Query: 231  IVSGSKSKSADMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMNYEM 410
            I+  ++      E TS P+IYAIGDV +G  ELTP AIKAG+LLA+RLF K +  M+Y  
Sbjct: 341  IIVDAQ------EATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSN 394

Query: 411  ISTTVFTPLEYACVGMTEEEAFSKLGDKNVEVYHCYFKPLEIVSMGQQPS-CYMKMICDV 587
            + TTVFTPLEY CVG++EEEA +  G ++VEVYH Y+KPLE     +  S CY+KM+C  
Sbjct: 395  VPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCYIKMVCMR 454

Query: 588  SKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITKRSN 767
               + V+GLH LG NAGE+ QGFA+ IK G ++ Q+  TVGIHPT +EEVVKLHI+KRS 
Sbjct: 455  EPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSG 514

Query: 768  IDPHLTG 788
            ++P +TG
Sbjct: 515  LEPTVTG 521

>sp|Q9Z0J5|TRXR2_RAT Thioredoxin reductase 2, mitochondrial precursor (TR3)
          Length = 526

 Score =  239 bits (609), Expect = 1e-62
 Identities = 124/239 (51%), Positives = 165/239 (69%), Gaps = 1/239 (0%)
 Frame = +3

Query: 75  SGKFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPNTKKIVSGSKSK 254
           + + +V W+   +  E    FDTVL+AIGR P T +LNL  A V+ +P  +KI+  ++  
Sbjct: 291 TNQLQVTWEDLASGKEDVGTFDTVLWAIGRVPETRNLNLEKAGVNTNPKNQKIIVDAQ-- 348

Query: 255 SADMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMNYEMISTTVFTP 434
               E TS P+IYAIGDV +G  ELTP AIKAG+LLA+RLF K +  MNY  + TTVFTP
Sbjct: 349 ----EATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMNYSNVPTTVFTP 404

Query: 435 LEYACVGMTEEEAFSKLGDKNVEVYHCYFKPLEIVSMGQQPS-CYMKMICDVSKSEKVVG 611
           LEY CVG++EEEA +  G +++EVYH Y+KPLE     +  S CY+KM+C     + V+G
Sbjct: 405 LEYGCVGLSEEEAVALHGQEHIEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLG 464

Query: 612 LHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITKRSNIDPHLTG 788
           LH LG NAGE+ QGFA+ I+ G ++ Q+  TVGIHPT +EEVVKLHI+KRS +DP +TG
Sbjct: 465 LHFLGPNAGEVTQGFALGIQCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLDPTVTG 523

>sp|Q9N2I8|TRXR2_BOVIN Thioredoxin reductase 2, mitochondrial precursor (TR3)
          Length = 511

 Score =  226 bits (575), Expect = 1e-58
 Identities = 122/237 (51%), Positives = 159/237 (67%), Gaps = 1/237 (0%)
 Frame = +3

Query: 81  KFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPNTKKIVSGSKSKSA 260
           + RV W    +  + +  FDTVL+AIGR P T  LNL  A V  +P T KI+  ++    
Sbjct: 278 QLRVTWVDLTSDRKDAGTFDTVLWAIGRVPETASLNLEKAGVHTNPVTGKILVDAQ---- 333

Query: 261 DMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMNYEMISTTVFTPLE 440
             E TS P+IYAIGDV +G  ELTP AI AGRLLA+RL  + +  M+Y  + TTVFTPLE
Sbjct: 334 --ETTSVPHIYAIGDVAEGRPELTPTAIMAGRLLAQRLSGRTSDLMDYSSVPTTVFTPLE 391

Query: 441 YACVGMTEEEAFSKLGDKNVEVYHCYFKPLEI-VSMGQQPSCYMKMICDVSKSEKVVGLH 617
           Y CVG++EE A ++ G+++VEVYH ++KPLE  V       CY+KM+C     + V+GLH
Sbjct: 392 YGCVGLSEEAAVARHGEEHVEVYHAFYKPLEFTVPQRDASQCYIKMVCLREPPQLVLGLH 451

Query: 618 ILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITKRSNIDPHLTG 788
            LG NAGE++QGFA+ IK G ++ QL  TVGIHPT AEEV KL I+KRS +DP +TG
Sbjct: 452 FLGPNAGEVIQGFALGIKCGASYQQLMRTVGIHPTCAEEVAKLRISKRSGLDPTVTG 508

>sp|O89049|TRXR1_RAT Thioredoxin reductase 1, cytoplasmic (TR) (TR1) (NADPH-dependent
           thioredoxin reductase)
          Length = 498

 Score =  219 bits (558), Expect = 9e-57
 Identities = 116/240 (48%), Positives = 155/240 (64%), Gaps = 1/240 (0%)
 Frame = +3

Query: 57  EVIQGDSGKFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPNTKKIV 236
           ++  G  G+ +V  K   +   + D F+TVL A+GRD CT  + L    V ++  T KI 
Sbjct: 258 QIEAGTPGRLKVTAKSTNSEETIEDEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKI- 316

Query: 237 SGSKSKSADMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMNYEMIS 416
                   D E+T+ P IYAIGD+L+G +ELTPVAI+AGRLLA+RL+   TV  +Y+ + 
Sbjct: 317 -----PVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTVKCDYDNVP 371

Query: 417 TTVFTPLEYACVGMTEEEAFSKLGDKNVEVYHCYFKPLE-IVSMGQQPSCYMKMICDVSK 593
           TTVFTPLEY C G++EE+A  K G++N+EVYH +F PLE  V       CY K+IC++  
Sbjct: 372 TTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKVICNLKD 431

Query: 594 SEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITKRSNID 773
           +E+VVG H+LG NAGE+ QGFA A K G+T  QL ST+GIHP  AE    L +TKRS  D
Sbjct: 432 NERVVGFHVLGPNAGEVTQGFAAA-KCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGD 490

>sp|Q9JMH6|TRXR1_MOUSE Thioredoxin reductase 1, cytoplasmic (TR) (TR1)
          Length = 499

 Score =  219 bits (558), Expect = 9e-57
 Identities = 114/240 (47%), Positives = 153/240 (63%), Gaps = 1/240 (0%)
 Frame = +3

Query: 57  EVIQGDSGKFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPNTKKIV 236
           ++  G  G+ RV  +   +   +   F+TVL A+GRD CT  + L    V ++  T KI 
Sbjct: 258 QIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKI- 316

Query: 237 SGSKSKSADMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMNYEMIS 416
                   D E+T+ P IYAIGD+L+G +ELTPVAI+AGRLLA+RL+    V  +Y+ + 
Sbjct: 317 -----PVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVP 371

Query: 417 TTVFTPLEYACVGMTEEEAFSKLGDKNVEVYHCYFKPLE-IVSMGQQPSCYMKMICDVSK 593
           TTVFTPLEY C G++EE+A  K G++N+EVYH +F PLE  V       CY K+IC++  
Sbjct: 372 TTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKD 431

Query: 594 SEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITKRSNID 773
            E+VVG H+LG NAGE+ QGFA A+K G+T  QL ST+GIHP  AE    L +TKRS  D
Sbjct: 432 DERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGD 491

>sp|O62768|TRXR1_BOVIN Thioredoxin reductase 1, cytoplasmic (TR) (TR1)
          Length = 499

 Score =  219 bits (558), Expect = 9e-57
 Identities = 118/242 (48%), Positives = 156/242 (64%), Gaps = 4/242 (1%)
 Frame = +3

Query: 51  PIEVIQ---GDSGKFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPN 221
           PI+V Q   G  G+ RV  K   +   +   ++TVL AIGRD CT  + L    V ++  
Sbjct: 253 PIKVEQIEAGTPGRLRVIAKSTDSDQTIEGEYNTVLLAIGRDACTRKIGLENVGVKINEK 312

Query: 222 TKKIVSGSKSKSADMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMN 401
           T KI         + E+T+ P IYAIGD+L+G +ELTPVAI+AGRLLA+RL+   TV  +
Sbjct: 313 TGKI------PVTEEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTVKCD 366

Query: 402 YEMISTTVFTPLEYACVGMTEEEAFSKLGDKNVEVYHCYFKPLE-IVSMGQQPSCYMKMI 578
           YE + TTVFTPLEY   G++EE+A  K G++NVEVYH YF PLE  +       CY K++
Sbjct: 367 YENVPTTVFTPLEYGSCGLSEEKAVEKFGEENVEVYHSYFWPLEWTIPSRDNNKCYAKVV 426

Query: 579 CDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITK 758
           C++  +E+VVG H+LG NAGE+ QGFA A+K G+T  QL ST+GIHP  AE    L +TK
Sbjct: 427 CNIKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKDQLDSTIGIHPVCAEVFTTLSVTK 486

Query: 759 RS 764
           RS
Sbjct: 487 RS 488

>sp|P91938|TRXR1_DROME Thioredoxin reductase 1, mitochondrial precursor (TrxR-1)
          Length = 596

 Score =  218 bits (556), Expect = 2e-56
 Identities = 115/243 (47%), Positives = 154/243 (63%), Gaps = 1/243 (0%)
 Frame = +3

Query: 51   PIEVIQGDSGKFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPNTKK 230
            P+ V + D GK  VK+K  +   E  D++DTVL+AIGR     DLNL        PN   
Sbjct: 355  PLSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNL--------PNAGV 406

Query: 231  IVSGSKSKSADMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMNYEM 410
             V   K      E T+  NIYA+GD++ G  ELTPVA+ AGRLLARRL+   T  M+Y+ 
Sbjct: 407  TVQKDKIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKD 466

Query: 411  ISTTVFTPLEYACVGMTEEEAFSKLGDKNVEVYHCYFKPLE-IVSMGQQPSCYMKMICDV 587
            ++TTVFTPLEYACVG++EE+A  + G   +EV+H Y+KP E  +       CY+K + + 
Sbjct: 467  VATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAER 526

Query: 588  SKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITKRSN 767
               ++V GLH +G  AGE++QGFA A+K G+T   L +TVGIHPT+AEE  +L ITKRS 
Sbjct: 527  HGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSG 586

Query: 768  IDP 776
            +DP
Sbjct: 587  LDP 589

>sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic precursor (TR) (TR1)
          Length = 499

 Score =  216 bits (551), Expect = 6e-56
 Identities = 117/242 (48%), Positives = 154/242 (63%), Gaps = 4/242 (1%)
 Frame = +3

Query: 51  PIEVIQ---GDSGKFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPN 221
           PI+V Q   G  G+ RV  +   +   +   ++TV+ AIGRD CT  + L    V ++  
Sbjct: 253 PIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEK 312

Query: 222 TKKIVSGSKSKSADMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMN 401
           T KI         D E+T+ P IYAIGD+L+  VELTPVAI+AGRLLA+RL+   TV  +
Sbjct: 313 TGKI------PVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCD 366

Query: 402 YEMISTTVFTPLEYACVGMTEEEAFSKLGDKNVEVYHCYFKPLE-IVSMGQQPSCYMKMI 578
           YE + TTVFTPLEY   G++EE+A  K G++N+EVYH YF PLE  +       CY K+I
Sbjct: 367 YENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKII 426

Query: 579 CDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITK 758
           C+   +E+VVG H+LG NAGE+ QGFA A+K G+T  QL ST+GIHP  AE    L +TK
Sbjct: 427 CNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTK 486

Query: 759 RS 764
           RS
Sbjct: 487 RS 488

>sp|Q9MYY8|TRXR1_PIG Thioredoxin reductase 1, cytoplasmic (TR) (TR1)
          Length = 499

 Score =  216 bits (551), Expect = 6e-56
 Identities = 117/242 (48%), Positives = 154/242 (63%), Gaps = 4/242 (1%)
 Frame = +3

Query: 51  PIEVIQ---GDSGKFRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLDLNLSAAKVSVDPN 221
           PI+V Q   G  G+ RV  +   +   +   ++TV+ AIGRD CT  + L    V ++  
Sbjct: 253 PIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEK 312

Query: 222 TKKIVSGSKSKSADMEKTSAPNIYAIGDVLQGGVELTPVAIKAGRLLARRLFHKETVHMN 401
           T KI         D E+T+ P IYAIGD+L+  VELTPVAI+AGRLLA+RL+   TV  +
Sbjct: 313 TGKI------PVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCD 366

Query: 402 YEMISTTVFTPLEYACVGMTEEEAFSKLGDKNVEVYHCYFKPLE-IVSMGQQPSCYMKMI 578
           YE + TTVFTPLEY   G++EE+A  K G++N+EVYH YF PLE  +       CY K+I
Sbjct: 367 YENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKII 426

Query: 579 CDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVVKLHITK 758
           C+   +E+VVG H+LG NAGE+ QGFA A+K G+T  QL ST+GIHP  AE    L +TK
Sbjct: 427 CNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTK 486

Query: 759 RS 764
           RS
Sbjct: 487 RS 488

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 118,914,628
Number of Sequences: 369166
Number of extensions: 2515108
Number of successful extensions: 7007
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6554
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6803
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 10383318715
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00002

  1. Dr_sW_001_A17
  2. Dr_sW_004_I10