Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_I10
(456 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Z0J5|TRXR2_RAT Thioredoxin reductase 2, mitochondrial ... 100 1e-21
sp|Q9JLT4|TRXR2_MOUSE Thioredoxin reductase 2, mitochondria... 100 1e-21
sp|Q9N2I8|TRXR2_BOVIN Thioredoxin reductase 2, mitochondria... 100 3e-21
sp|Q9NNW7|TRXR2_HUMAN Thioredoxin reductase 2, mitochondria... 99 6e-21
sp|P30635|GSHR_CAEEL Probable glutathione reductase (GR) (G... 94 1e-19
sp|O62768|TRXR1_BOVIN Thioredoxin reductase 1, cytoplasmic ... 90 2e-18
sp|Q9VNT5|TRXR2_DROME Thioredoxin reductase 2, mitochondria... 89 3e-18
sp|Q9JMH6|TRXR1_MOUSE Thioredoxin reductase 1, cytoplasmic ... 89 5e-18
sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic ... 88 1e-17
sp|Q9MYY8|TRXR1_PIG Thioredoxin reductase 1, cytoplasmic (T... 88 1e-17
>sp|Q9Z0J5|TRXR2_RAT Thioredoxin reductase 2, mitochondrial precursor (TR3)
Length = 526
Score = 100 bits (250), Expect = 1e-21
Identities = 46/79 (58%), Positives = 60/79 (75%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY+KM+C + V+GLH LG NAGE+ QGFA+ I+ G ++ Q+ TVGIHPT +EEVV
Sbjct: 448 CYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIQCGASYAQVMQTVGIHPTCSEEVV 507
Query: 212 KLHITKRSNIDPHLTGC*G 268
KLHI+KRS +DP +TGC G
Sbjct: 508 KLHISKRSGLDPTVTGCCG 526
>sp|Q9JLT4|TRXR2_MOUSE Thioredoxin reductase 2, mitochondrial precursor (TR3)
Length = 524
Score = 100 bits (250), Expect = 1e-21
Identities = 46/79 (58%), Positives = 60/79 (75%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY+KM+C + V+GLH LG NAGE+ QGFA+ IK G ++ Q+ TVGIHPT +EEVV
Sbjct: 446 CYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVV 505
Query: 212 KLHITKRSNIDPHLTGC*G 268
KLHI+KRS ++P +TGC G
Sbjct: 506 KLHISKRSGLEPTVTGCCG 524
>sp|Q9N2I8|TRXR2_BOVIN Thioredoxin reductase 2, mitochondrial precursor (TR3)
Length = 511
Score = 99.8 bits (247), Expect = 3e-21
Identities = 47/79 (59%), Positives = 59/79 (74%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY+KM+C + V+GLH LG NAGE++QGFA+ IK G ++ QL TVGIHPT AEEV
Sbjct: 433 CYIKMVCLREPPQLVLGLHFLGPNAGEVIQGFALGIKCGASYQQLMRTVGIHPTCAEEVA 492
Query: 212 KLHITKRSNIDPHLTGC*G 268
KL I+KRS +DP +TGC G
Sbjct: 493 KLRISKRSGLDPTVTGCCG 511
>sp|Q9NNW7|TRXR2_HUMAN Thioredoxin reductase 2, mitochondrial precursor (TR3) (TR-beta)
(Selenoprotein Z) (SelZ)
Length = 524
Score = 98.6 bits (244), Expect = 6e-21
Identities = 46/79 (58%), Positives = 59/79 (74%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY+KM+C + V+GLH LG NAGE+ QGFA+ IK G ++ Q+ TVGIHPT +EEVV
Sbjct: 446 CYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVV 505
Query: 212 KLHITKRSNIDPHLTGC*G 268
KL I+KRS +DP +TGC G
Sbjct: 506 KLRISKRSGLDPTVTGCCG 524
>sp|P30635|GSHR_CAEEL Probable glutathione reductase (GR) (GRase)
Length = 503
Score = 94.4 bits (233), Expect = 1e-19
Identities = 42/79 (53%), Positives = 57/79 (72%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY+K +C +S+K++GLH +G NA E++QG+AVA + GI+ L +T+ IHP S+EE V
Sbjct: 425 CYVKAVCTRDESQKILGLHFVGPNAAEVIQGYAVAFRVGISMSDLQNTIAIHPCSSEEFV 484
Query: 212 KLHITKRSNIDPHLTGC*G 268
KLHITKRS DP GC G
Sbjct: 485 KLHITKRSGQDPRTQGCCG 503
>sp|O62768|TRXR1_BOVIN Thioredoxin reductase 1, cytoplasmic (TR) (TR1)
Length = 499
Score = 90.1 bits (222), Expect = 2e-18
Identities = 42/79 (53%), Positives = 55/79 (69%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY K++C++ +E+VVG H+LG NAGE+ QGFA A+K G+T QL ST+GIHP AE
Sbjct: 421 CYAKVVCNIKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKDQLDSTIGIHPVCAEVFT 480
Query: 212 KLHITKRSNIDPHLTGC*G 268
L +TKRS + TGC G
Sbjct: 481 TLSVTKRSGGNILQTGCCG 499
>sp|Q9VNT5|TRXR2_DROME Thioredoxin reductase 2, mitochondrial precursor (TrxR-2)
Length = 516
Score = 89.4 bits (220), Expect = 3e-18
Identities = 41/77 (53%), Positives = 55/77 (71%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY+K + +VS +K++GLH +G AGE++QGFA A+K G+T L +TVGIHPT+AEE
Sbjct: 438 CYLKAVAEVSGDQKILGLHYIGPVAGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFT 497
Query: 212 KLHITKRSNIDPHLTGC 262
+L ITKRS DP C
Sbjct: 498 RLSITKRSGRDPTPASC 514
>sp|Q9JMH6|TRXR1_MOUSE Thioredoxin reductase 1, cytoplasmic (TR) (TR1)
Length = 499
Score = 89.0 bits (219), Expect = 5e-18
Identities = 43/79 (54%), Positives = 54/79 (68%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY K+IC++ E+VVG H+LG NAGE+ QGFA A+K G+T QL ST+GIHP AE
Sbjct: 421 CYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFT 480
Query: 212 KLHITKRSNIDPHLTGC*G 268
L +TKRS D +GC G
Sbjct: 481 TLSVTKRSGGDILQSGCCG 499
>sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic precursor (TR) (TR1)
Length = 499
Score = 87.8 bits (216), Expect = 1e-17
Identities = 42/79 (53%), Positives = 52/79 (65%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY K+IC+ +E+VVG H+LG NAGE+ QGFA A+K G+T QL ST+GIHP AE
Sbjct: 421 CYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFT 480
Query: 212 KLHITKRSNIDPHLTGC*G 268
L +TKRS GC G
Sbjct: 481 TLSVTKRSGASILQAGCCG 499
>sp|Q9MYY8|TRXR1_PIG Thioredoxin reductase 1, cytoplasmic (TR) (TR1)
Length = 499
Score = 87.8 bits (216), Expect = 1e-17
Identities = 42/79 (53%), Positives = 52/79 (65%)
Frame = +2
Query: 32 CYMKMICDVSKSEKVVGLHILGLNAGEILQGFAVAIKQGITHGQLCSTVGIHPTSAEEVV 211
CY K+IC+ +E+VVG H+LG NAGE+ QGFA A+K G+T QL ST+GIHP AE
Sbjct: 421 CYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFT 480
Query: 212 KLHITKRSNIDPHLTGC*G 268
L +TKRS GC G
Sbjct: 481 TLSVTKRSGASILQAGCCG 499
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,681,555
Number of Sequences: 369166
Number of extensions: 1014042
Number of successful extensions: 2748
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2699
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2746
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2484837250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)