Planaria EST Database


DrC_02986

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02986
         (485 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9NYB9|ABI2_HUMAN  Abl-interactor 2 (Abelson interactor 2...   105   7e-23
sp|P62484|ABI2_MOUSE  Abl-interactor 2 (Abelson interactor 2...   104   9e-23
sp|Q8IZP0|ABI1_HUMAN  Abl-interactor 1 (Abelson interactor 1...    99   5e-21
sp|Q8CBW3|ABI1_MOUSE  Abl-interactor 1 (Abelson interactor 1...    99   5e-21
sp|Q9QZM5|ABI1_RAT  Abl-interactor 1 (Abelson interactor 1) ...    99   5e-21
sp|Q9P2A4|ABI3_HUMAN  ABI gene family member 3 (New molecule...    86   6e-17
sp|Q8BYZ1|ABI3_MOUSE  ABI gene family member 3 (New molecule...    80   3e-15
sp|Q9NZM3|ITSN2_HUMAN  Intersectin-2 (SH3 domain-containing ...    72   9e-13
sp|Q9Z0R6|ITSN2_MOUSE  Intersectin-2 (SH3 domain-containing ...    71   1e-12
sp|Q15811|ITSN1_HUMAN  Intersectin 1 (SH3 domain-containing ...    66   4e-11
>sp|Q9NYB9|ABI2_HUMAN Abl-interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding
           protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
          Length = 513

 Score =  105 bits (261), Expect = 7e-23
 Identities = 53/116 (45%), Positives = 72/116 (62%)
 Frame = +1

Query: 49  PPPPNVEQFQRPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAPSQY 228
           PPPP VE+   P  +E          Y  +   +      PY      ++ D  WAP  Y
Sbjct: 403 PPPPPVEE---PVFDESPPPPPPPEDYEEEEAAVVEYSD-PY------AEEDPPWAPRSY 452

Query: 229 ICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNL 396
           + KVV +Y+Y ++K+DELSFQE  +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++
Sbjct: 453 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 508
>sp|P62484|ABI2_MOUSE Abl-interactor 2 (Abelson interactor 2) (Abi-2)
          Length = 446

 Score =  104 bits (260), Expect = 9e-23
 Identities = 53/116 (45%), Positives = 72/116 (62%)
 Frame = +1

Query: 49  PPPPNVEQFQRPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAPSQY 228
           PPPP VE+   P  +E          Y  +   +      PY      ++ D  WAP  Y
Sbjct: 336 PPPPPVEE---PVFDESPPPPPPPEDYEEEEAAVVEYSD-PY------AEEDPPWAPRAY 385

Query: 229 ICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNL 396
           + KVV +Y+Y ++K+DELSFQE  +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++
Sbjct: 386 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 441
>sp|Q8IZP0|ABI1_HUMAN Abl-interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3
           domain-binding protein 1) (Eps8 SH3 domain-binding
           protein) (Eps8-binding protein) (e3B1) (Nap1-binding
           protein) (Nap1BP) (Abl-binding protein 4) (AblBP4)
          Length = 508

 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 51/117 (43%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
 Frame = +1

Query: 49  PPPPNVEQFQ-RPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAPSQ 225
           PPP ++  F   PP      +D     Y  +   +      PY      +  D  WAP  
Sbjct: 399 PPPDDIPMFDDSPPPPPPPPVD-----YEDEEAAVVQYND-PY------ADGDPAWAPKN 446

Query: 226 YICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNL 396
           YI KVV +Y+Y ++KDDELSF E  +IYV+KKN+DGW+EGV N  TGLFPGNYV+++
Sbjct: 447 YIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 503
>sp|Q8CBW3|ABI1_MOUSE Abl-interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3
           domain-binding protein 1) (Eps8 SH3 domain-binding
           protein) (Eps8-binding protein) (e3B1) (Ablphilin-1)
          Length = 481

 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 3/119 (2%)
 Frame = +1

Query: 49  PPPPNVEQFQR---PPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAP 219
           PPP ++  F     PP    ++ +  +   +  S         PY      +  D  WAP
Sbjct: 372 PPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYS--------DPY------ADGDPAWAP 417

Query: 220 SQYICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNL 396
             YI KVV +Y+Y ++KDDELSF+E  +IYV+KKN+DGW+EGV N  TGLFPGNYV+++
Sbjct: 418 KNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESI 476
>sp|Q9QZM5|ABI1_RAT Abl-interactor 1 (Abelson interactor 1) (Abi-1) (Eps8 SH3 domain
           binding protein) (Eps8 binding protein) (e3B1)
          Length = 476

 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 3/119 (2%)
 Frame = +1

Query: 49  PPPPNVEQFQR---PPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAP 219
           PPP ++  F     PP    ++ +  +   +  S         PY      +  D  WAP
Sbjct: 367 PPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYS--------DPY------ADGDPAWAP 412

Query: 220 SQYICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNL 396
             YI KVV +Y+Y ++KDDELSF+E  +IYV+KKN+DGW+EGV N  TGLFPGNYV+++
Sbjct: 413 KNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESI 471
>sp|Q9P2A4|ABI3_HUMAN ABI gene family member 3 (New molecule including SH3) (Nesh)
          Length = 366

 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 47/120 (39%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
 Frame = +1

Query: 49  PPPPNVEQFQRPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIK------SQSDEV 210
           PPP  VE FQRPP+ E+++     +  +   + +    P   D L +          +  
Sbjct: 245 PPPAAVEVFQRPPTLEELS-PPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPS 303

Query: 211 WAPSQYICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 390
           W P+ Y+ KVVTLY Y   KD+ELSF E  +I V ++ +DGW EGV +  TG FPGNYV+
Sbjct: 304 WVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363
>sp|Q8BYZ1|ABI3_MOUSE ABI gene family member 3 (New molecule including SH3) (Nesh)
          Length = 367

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 43/115 (37%), Positives = 63/115 (54%)
 Frame = +1

Query: 46  LPPPPNVEQFQRPPSNEQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAPSQ 225
           LPPPP   +  +PP   ++ +         D +G+    P  +         +  W P+ 
Sbjct: 259 LPPPPL--EVSQPPLEAELPLPPPP-ALEGDELGLLPPPPPGF------GPDEPSWVPAS 309

Query: 226 YICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 390
           Y+ KVVTLY Y + KD+ELSF E  +I V+++ +DGW EGV +  TG FPGNYV+
Sbjct: 310 YLEKVVTLYPYTRQKDNELSFSEGTVICVIRRYSDGWCEGVSSEGTGFFPGNYVE 364
>sp|Q9NZM3|ITSN2_HUMAN Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18)
            (SH3P18-like WASP associated protein)
          Length = 1696

 Score = 71.6 bits (174), Expect = 9e-13
 Identities = 31/75 (41%), Positives = 50/75 (66%), Gaps = 1/75 (1%)
 Frame = +1

Query: 169  PYDVLRIKSQSDEVWAPSQY-ICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEG 345
            P   +++   S E   P+ + +C+V+ +Y+Y  N +DELSF + +LI V+ K++  WW+G
Sbjct: 1107 PASHVKLLGPSSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQG 1166

Query: 346  VMNGRTGLFPGNYVQ 390
             +NG TGLFP NYV+
Sbjct: 1167 EINGVTGLFPSNYVK 1181

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 20/50 (40%), Positives = 31/50 (62%)
 Frame = +1

Query: 241  VTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 390
            + LY Y   +  +L+F E E I V +K+ + WW G +  R+G+FP NYV+
Sbjct: 986  IALYPYSSVEPGDLTFTEGEEILVTQKDGE-WWTGSIGDRSGIFPSNYVK 1034

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 5/52 (9%)
 Frame = +1

Query: 256  YLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGR-----TGLFPGNYVQNL 396
            Y+ +  ++LS    +LI ++KKN  GWW+G +  R      G FP ++V+ L
Sbjct: 1063 YVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLL 1114

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 25/103 (24%), Positives = 43/103 (41%), Gaps = 2/103 (1%)
 Frame = +1

Query: 94   EQINIDKNQNRYISDSVGIAHLQPTPYDVLRIKSQSDEVWAPSQYICKVVTLYEYLQNKD 273
            +++  +K Q +   +       Q    D L+ + +  E    +  +     LY +     
Sbjct: 716  KRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRET---ASVLVNYRALYPFEARNH 772

Query: 274  DELSFQENELIYVVKKN--NDGWWEGVMNGRTGLFPGNYVQNL 396
            DE+SF   ++I V +K     GW  G   G  G FP NYV+ +
Sbjct: 773  DEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 815

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 17/52 (32%), Positives = 32/52 (61%)
 Frame = +1

Query: 235  KVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 390
            K   L  +   KD+ L+F ++++I V+++  + WW G ++G  G FP +YV+
Sbjct: 901  KAQALCSWTAKKDNHLNFSKHDIITVLEQQ-ENWWFGEVHGGRGWFPKSYVK 951
>sp|Q9Z0R6|ITSN2_MOUSE Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains
            protein 2) (EH domain and SH3 domain regulator of
            endocytosis 2)
          Length = 1658

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 30/75 (40%), Positives = 50/75 (66%), Gaps = 1/75 (1%)
 Frame = +1

Query: 169  PYDVLRIKSQSDEVWAPSQY-ICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEG 345
            P   +++   S E   P+ + +C+V+ +Y+Y+ N +DEL+F + +LI V+ K++  WW+G
Sbjct: 1068 PASHVKLLGPSSERTMPTFHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQG 1127

Query: 346  VMNGRTGLFPGNYVQ 390
              NG TGLFP NYV+
Sbjct: 1128 ETNGLTGLFPSNYVK 1142

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 21/50 (42%), Positives = 31/50 (62%)
 Frame = +1

Query: 241  VTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 390
            + LY Y   +  +L+F E E I V +K+ + WW G +  RTG+FP NYV+
Sbjct: 947  IALYSYSSVEPGDLTFTEGEEILVTQKDGE-WWTGSIGERTGIFPSNYVR 995

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 5/52 (9%)
 Frame = +1

Query: 256  YLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGR-----TGLFPGNYVQNL 396
            Y  +  ++LS    +LI ++KKN  GWW+G +  R      G FP ++V+ L
Sbjct: 1024 YAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLL 1075

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
 Frame = +1

Query: 247 LYEYLQNKDDELSFQENELIYVVKKN--NDGWWEGVMNGRTGLFPGNYVQNL 396
           LY +     DE+SF   ++I V +K     GW  G   G+ G FP NYV+ +
Sbjct: 725 LYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQGKFGWFPCNYVEKV 776

 Score = 37.0 bits (84), Expect = 0.024
 Identities = 16/52 (30%), Positives = 32/52 (61%)
 Frame = +1

Query: 235  KVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 390
            K   L  +   K++ L+F ++++I V+++  + WW G ++G  G FP +YV+
Sbjct: 855  KAQALCSWTAKKENHLNFSKHDVITVLEQQ-ENWWFGEVHGGRGWFPKSYVK 905
>sp|Q15811|ITSN1_HUMAN Intersectin 1 (SH3 domain-containing protein 1A) (SH3P17)
          Length = 1721

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 24/54 (44%), Positives = 39/54 (72%)
 Frame = +1

Query: 229  ICKVVTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 390
            +C+V+ +Y+Y    DDEL+F + ++I V+ K +  WW+G +NG+ GLFP NYV+
Sbjct: 1157 VCQVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK 1210

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 19/50 (38%), Positives = 33/50 (66%)
 Frame = +1

Query: 241  VTLYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 390
            + +Y Y  ++  +L+FQ+ ++I V KK+ D WW G +  + G+FP NYV+
Sbjct: 1008 IAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVFPSNYVR 1056

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 19/48 (39%), Positives = 32/48 (66%)
 Frame = +1

Query: 247  LYEYLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 390
            LY +   KD+ L+F +N++I V+++  D WW G + G+ G FP +YV+
Sbjct: 921  LYPWRAKKDNHLNFNKNDVITVLEQQ-DMWWFGEVQGQKGWFPKSYVK 967

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
 Frame = +1

Query: 256  YLQNKDDELSFQENELIYVVKKNNDGWWEGVMNGR-----TGLFPGNYVQNLN 399
            Y     ++L+    +LI + KKN  GWWEG +  R      G FP NYV+ L+
Sbjct: 1085 YTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLS 1137

 Score = 36.2 bits (82), Expect = 0.041
 Identities = 16/57 (28%), Positives = 27/57 (47%), Gaps = 7/57 (12%)
 Frame = +1

Query: 247 LYEYLQNKDDELSFQENELIYVV-------KKNNDGWWEGVMNGRTGLFPGNYVQNL 396
           LY +     DE++ Q  +++ V        +    GW  G + G+TG FP NY + +
Sbjct: 748 LYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,179,058
Number of Sequences: 369166
Number of extensions: 947022
Number of successful extensions: 3328
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3053
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3227
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2921208590
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)