Planaria EST Database


DrC_02982

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02982
         (861 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9UII4|HERC5_HUMAN  HECT domain and RCC1-like domain prot...    64   7e-10
sp|Q15034|HERC3_HUMAN  HECT domain and RCC1-like domain prot...    61   4e-09
sp|Q8BK67|RCC2_MOUSE  RCC2 protein                                 60   8e-09
sp|Q9P258|RCC2_HUMAN  RCC2 protein (Telophase disk protein o...    59   2e-08
sp|Q91ZR4|NEK8_MOUSE  Serine/threonine-protein kinase Nek8 (...    59   2e-08
sp|Q52KW8|RCC2_XENLA  RCC2 protein homolog                         59   2e-08
sp|Q86SG6|NEK8_HUMAN  Serine/threonine-protein kinase Nek8 (...    57   5e-08
sp|Q6NYE2|RCC2_BRARE  RCC2 protein homolog                         57   9e-08
sp|Q90XC2|NEK8_BRARE  Serine/threonine-protein kinase Nek8 (...    54   6e-07
sp|Q9N1T2|RPGR_CANFA  X-linked retinitis pigmentosa GTPase r...    52   2e-06
>sp|Q9UII4|HERC5_HUMAN HECT domain and RCC1-like domain protein 5 (Cyclin-E binding
           protein 1)
          Length = 1024

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 4/81 (4%)
 Frame = +2

Query: 8   LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDG----TTTTNSRPRIIETLTGK 175
           L  KKII + CG  H +  ++ GE+++WG N  GQLG G    +TTT   P+I+E L G 
Sbjct: 135 LQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTT---PQIVEHLAGV 191

Query: 176 GINRVACGSAHTLAWTTVSGN 238
            + +++ G AH++A  ++SGN
Sbjct: 192 PLAQISAGEAHSMA-LSMSGN 211

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 28/76 (36%), Positives = 44/76 (57%)
 Frame = +2

Query: 8   LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINR 187
           L+ +K+  VACG  H    T+DG ++++G    GQLG  +T    RP ++  L G  + +
Sbjct: 240 LDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQ 299

Query: 188 VACGSAHTLAWTTVSG 235
           +ACG  HTLA+ +  G
Sbjct: 300 IACGRWHTLAYVSDLG 315

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 24/67 (35%), Positives = 37/67 (55%)
 Frame = +2

Query: 23  IIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACGS 202
           +  ++ G  H +  +  G +YSWG N+ GQLG G T +   P +IE L  + +  VACG 
Sbjct: 193 LAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGG 252

Query: 203 AHTLAWT 223
           +H+   T
Sbjct: 253 SHSALLT 259

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
 Frame = +2

Query: 2   AQLNRKKIIDVACGSLHCICCTED-GEVYSWGDNDEGQLGDGTTTTNSRP 148
           A+L   ++  +ACG  H +    D G+V+S+G   +GQLG+G T     P
Sbjct: 290 AELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTRDQLMP 339
>sp|Q15034|HERC3_HUMAN HECT domain and RCC1-like domain protein 3
          Length = 1050

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 27/72 (37%), Positives = 45/72 (62%), Gaps = 1/72 (1%)
 Frame = +2

Query: 5   QLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTT-TTNSRPRIIETLTGKGI 181
           +LN++ I+ V+CG+ HC+    DG+ ++WG N  GQLG G    + + P+ + +L G  +
Sbjct: 133 KLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPL 192

Query: 182 NRVACGSAHTLA 217
            +VA G AH+ A
Sbjct: 193 AQVAAGGAHSFA 204

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 36/102 (35%), Positives = 52/102 (50%), Gaps = 11/102 (10%)
 Frame = +2

Query: 23  IIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIETLTGKGINRVACG 199
           II VACG  H +  ++ G+++SWG   +GQLG  TT  + + PR+I+ L  + I +V+CG
Sbjct: 86  IIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCG 145

Query: 200 SAHTLAWTT-----VSGNKSH-----ETESPEQRLPMSTRPI 295
           + H LA          G  SH       E P Q  P   R +
Sbjct: 146 NWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSL 187

 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 26/76 (34%), Positives = 41/76 (53%)
 Frame = +2

Query: 8   LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINR 187
           L  +K++ ++CG  H    T+ G V+++G    GQLG  +      PR +  L G  + +
Sbjct: 239 LRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQ 298

Query: 188 VACGSAHTLAWTTVSG 235
           +ACG  HTLA+   SG
Sbjct: 299 IACGRQHTLAFVPSSG 314

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 28/70 (40%), Positives = 41/70 (58%)
 Frame = +2

Query: 8   LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINR 187
           ++ + + +VACG  H +   EDGEVY+ G N +GQLG       ++P  I  L  + I  
Sbjct: 31  ISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGH--EREGNKPEQIGALADQHIIH 88

Query: 188 VACGSAHTLA 217
           VACG +H+LA
Sbjct: 89  VACGESHSLA 98

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 21/71 (29%), Positives = 31/71 (43%)
 Frame = +2

Query: 23  IIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACGS 202
           +  VA G  H    +  G V+ WG N+ GQLG         P  ++ L  + +  ++CG 
Sbjct: 192 LAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGE 251

Query: 203 AHTLAWTTVSG 235
            HT   T   G
Sbjct: 252 EHTAVLTKSGG 262
>sp|Q8BK67|RCC2_MOUSE RCC2 protein
          Length = 520

 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 28/69 (40%), Positives = 43/69 (62%)
 Frame = +2

Query: 17  KKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVAC 196
           + ++  +C + H +  T +G+++SWG N++GQLG G T     PR+IE L+ + I   AC
Sbjct: 149 RTVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEALSHEAIVLAAC 207

Query: 197 GSAHTLAWT 223
           G  HTLA T
Sbjct: 208 GRNHTLALT 216

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 22/69 (31%), Positives = 37/69 (53%)
 Frame = +2

Query: 8   LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINR 187
           L+ + I+  ACG  H +  T+ G V+++G+N  GQLG G  T            G+ I +
Sbjct: 197 LSHEAIVLAACGRNHTLALTDTGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITK 256

Query: 188 VACGSAHTL 214
           +ACG+  ++
Sbjct: 257 MACGAEFSM 265

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
 Frame = +2

Query: 29  DVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIE--TLTGKGINRVACGS 202
           DVACG+ H +       V+SWG    G+LG         PR+++     G+G  ++  G 
Sbjct: 332 DVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGATQIYAGY 391

Query: 203 AHTLAWTTVSG 235
             + A + V G
Sbjct: 392 TCSFAVSEVGG 402
>sp|Q9P258|RCC2_HUMAN RCC2 protein (Telophase disk protein of 60 kDa) (RCC1-like protein
           TD-60)
          Length = 522

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 28/69 (40%), Positives = 43/69 (62%)
 Frame = +2

Query: 17  KKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVAC 196
           + ++  +C + H +  T +G+++SWG N++GQLG G T     PR+IE L+ + I   AC
Sbjct: 151 RTVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAAC 209

Query: 197 GSAHTLAWT 223
           G  HTLA T
Sbjct: 210 GRNHTLALT 218

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 23/69 (33%), Positives = 37/69 (53%)
 Frame = +2

Query: 8   LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINR 187
           L+ + I+  ACG  H +  TE G V+++G+N  GQLG G  T            G+ I +
Sbjct: 199 LSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITK 258

Query: 188 VACGSAHTL 214
           +ACG+  ++
Sbjct: 259 MACGAEFSM 267

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
 Frame = +2

Query: 29  DVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIE--TLTGKGINRVACGS 202
           DVACG+ H +       V+SWG    G+LG         PR+++     G+G +++  G 
Sbjct: 334 DVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGY 393

Query: 203 AHTLAWTTVSG 235
             + A + V G
Sbjct: 394 TCSFAVSEVGG 404
>sp|Q91ZR4|NEK8_MOUSE Serine/threonine-protein kinase Nek8 (NimA-related protein kinase
           8)
          Length = 698

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 28/65 (43%), Positives = 39/65 (60%)
 Frame = +2

Query: 32  VACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACGSAHT 211
           VACG L   C T+ G + ++G    G LG G  T  S+P I+E L G  + +VACG++H 
Sbjct: 402 VACGDLFTACLTDRGIIMTFGSGSNGCLGHGNLTDISQPTIVEALLGYEMVQVACGASHV 461

Query: 212 LAWTT 226
           LA +T
Sbjct: 462 LALST 466

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 23/69 (33%), Positives = 42/69 (60%)
 Frame = +2

Query: 20  KIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACG 199
           +++ VACG+ H +  + DGE+++WG  D G+LG GT  +++ P+ +    G+   RV CG
Sbjct: 450 EMVQVACGASHVLALSTDGELFAWGRGDGGRLGLGTRESHNCPQQVPVAPGQEAQRVVCG 509

Query: 200 SAHTLAWTT 226
              ++  T+
Sbjct: 510 IDSSMILTS 518

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 24/72 (33%), Positives = 39/72 (54%)
 Frame = +2

Query: 2   AQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGI 181
           A L+++ ++ V  G+ H    T  G+ Y++G N  GQLG  +   +  P  ++ L G  +
Sbjct: 562 APLDQEPLLCVDLGTAHSAAITASGDCYTFGSNQHGQLGTSSRRVSRAPCRVQGLEGIKM 621

Query: 182 NRVACGSAHTLA 217
             VACG A T+A
Sbjct: 622 VMVACGDAFTVA 633

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
 Frame = +2

Query: 20  KIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIETLTGKGINRVAC 196
           K++ VACG    +    +GEVYSWG    G+LG         RP  ++      +  V+C
Sbjct: 620 KMVMVACGDAFTVAVGAEGEVYSWGKGTRGRLGRRDEDAGLPRPVQLDETHPYMVTSVSC 679

Query: 197 GSAHTL 214
              +TL
Sbjct: 680 CHGNTL 685
>sp|Q52KW8|RCC2_XENLA RCC2 protein homolog
          Length = 513

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 37/102 (36%), Positives = 50/102 (49%), Gaps = 17/102 (16%)
 Frame = +2

Query: 20  KIIDVACGSL--HCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVA 193
           ++  VA GS   H +  T +G+++SWG ND+GQLG G       P++IE+L G+     A
Sbjct: 140 QVRSVASGSCAAHSLLITVEGKLWSWGRNDKGQLGHGDIKRIDVPKLIESLKGEVFVHAA 199

Query: 194 CGSAHTLAWTTVS---------------GNKSHETESPEQRL 274
           CG  HTLA T                  GNK+    SP Q L
Sbjct: 200 CGRNHTLALTENGSVYAFGENKMGQLGLGNKTDAVPSPAQIL 241

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 26/70 (37%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
 Frame = +2

Query: 8   LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETL-TGKGIN 184
           L  +  +  ACG  H +  TE+G VY++G+N  GQLG G   T++ P   + L  G+ I 
Sbjct: 190 LKGEVFVHAACGRNHTLALTENGSVYAFGENKMGQLGLG-NKTDAVPSPAQILYNGQPIT 248

Query: 185 RVACGSAHTL 214
           +VACG+  ++
Sbjct: 249 KVACGAEFSM 258

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
 Frame = +2

Query: 29  DVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIE--TLTGKGINRVACGS 202
           D+ACG  H +       V+SWG    G+LG         PR+++     G+G  ++  G+
Sbjct: 325 DIACGINHSLILDSQKRVFSWGFGGYGRLGHSEQRDEMVPRLVKLFDFPGRGAAQIYAGA 384

Query: 203 AHTLAWTTVSG 235
             + A + + G
Sbjct: 385 TCSFAVSEMGG 395

 Score = 33.9 bits (76), Expect = 0.60
 Identities = 23/89 (25%), Positives = 48/89 (53%), Gaps = 3/89 (3%)
 Frame = +2

Query: 20  KIIDVACGSLHCICCTEDGEVYSWGDNDE-GQLG--DGTTTTNSRPRIIETLTGKGINRV 190
           K+  +ACG    I   ++  + SWG +   G+LG  D    +++  + ++TL G   ++V
Sbjct: 422 KVRSLACGKSSIIVAADESTI-SWGPSPTFGELGYGDNKAKSSTTAQEVKTLDGIYSDQV 480

Query: 191 ACGSAHTLAWTTVSGNKSHETESPEQRLP 277
             G++HTL    V+ +++ + +   ++LP
Sbjct: 481 IMGNSHTL---VVARDETEQDKEKLKKLP 506
>sp|Q86SG6|NEK8_HUMAN Serine/threonine-protein kinase Nek8 (NimA-related protein kinase
           8) (NIMA-related kinase 12a)
          Length = 692

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 27/65 (41%), Positives = 39/65 (60%)
 Frame = +2

Query: 32  VACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACGSAHT 211
           VACG     C T+ G + ++G    G LG G+ T  S+P I+E L G  + +VACG++H 
Sbjct: 396 VACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHV 455

Query: 212 LAWTT 226
           LA +T
Sbjct: 456 LALST 460

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 21/60 (35%), Positives = 37/60 (61%)
 Frame = +2

Query: 20  KIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACG 199
           +++ VACG+ H +  + + E+++WG  D G+LG GT  ++S P+ +    G+   RV CG
Sbjct: 444 EMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCG 503

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 24/72 (33%), Positives = 39/72 (54%)
 Frame = +2

Query: 2   AQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGI 181
           A L+++ ++ +  G+ H    T  G+ Y++G N  GQLG  T   +  P  ++ L G  +
Sbjct: 556 APLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKM 615

Query: 182 NRVACGSAHTLA 217
             VACG A T+A
Sbjct: 616 AMVACGDAFTVA 627

 Score = 33.9 bits (76), Expect = 0.60
 Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
 Frame = +2

Query: 20  KIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIETLTGKGINRVAC 196
           K+  VACG    +    + EVYSWG    G+LG         RP  ++      +  V+C
Sbjct: 614 KMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673

Query: 197 GSAHTL 214
              +TL
Sbjct: 674 CHGNTL 679
>sp|Q6NYE2|RCC2_BRARE RCC2 protein homolog
          Length = 495

 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 27/58 (46%), Positives = 36/58 (62%)
 Frame = +2

Query: 50  HCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACGSAHTLAWT 223
           H +  T +G+++SWG ND+GQLG G T     P++IE L  + I   ACG  HTLA T
Sbjct: 134 HSLIITTEGKLWSWGRNDKGQLGHGDTKRLEAPKLIEGLGEEVIVAAACGRNHTLALT 191

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 25/69 (36%), Positives = 37/69 (53%)
 Frame = +2

Query: 8   LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINR 187
           L  + I+  ACG  H +  TE+G VY++G+N  GQLG G  T            G+ I +
Sbjct: 172 LGEEVIVAAACGRNHTLALTENGTVYTFGENKLGQLGQGNQTDAVLSPATIQYNGQPIVK 231

Query: 188 VACGSAHTL 214
           VACG+  ++
Sbjct: 232 VACGAEFSM 240

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
 Frame = +2

Query: 29  DVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIE--TLTGKGINRVACGS 202
           DVACG+ H +       V+SWG    G+LG         PR+++     G+G  ++ CG 
Sbjct: 307 DVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGATQIYCGY 366

Query: 203 AHTLAWTTVSG 235
             + A + + G
Sbjct: 367 QCSFALSEMGG 377

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
 Frame = +2

Query: 20  KIIDVACGSLHCICCTEDGEVYSWGDNDE-GQL--GDGTTTTNSRPRIIETLTGKGINRV 190
           KI  +ACG    I   +D  + SWG +   G+L  GD    +++  + ++TL G    +V
Sbjct: 404 KIRSLACGKSSIIVAADDSTI-SWGPSPTFGELGYGDNKPKSSTTAQEVKTLDGVYSEQV 462

Query: 191 ACGSAHTL 214
             G +H+L
Sbjct: 463 VMGYSHSL 470

 Score = 30.8 bits (68), Expect = 5.1
 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 24/94 (25%)
 Frame = +2

Query: 5   QLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLG---DGTTTTNSR---------P 148
           Q N + I+ VACG+   +     G +YS+G  + GQLG   DG     ++         P
Sbjct: 223 QYNGQPIVKVACGAEFSMIVDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEFDCELIP 282

Query: 149 R-----IIETLTGKGI-------NRVACGSAHTL 214
           R     I +T  G+ +         VACG+ HTL
Sbjct: 283 RRVAIFIEKTKDGQVLPVPNVVARDVACGANHTL 316
>sp|Q90XC2|NEK8_BRARE Serine/threonine-protein kinase Nek8 (NimA-related protein kinase
           8)
          Length = 697

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 25/67 (37%), Positives = 39/67 (58%)
 Frame = +2

Query: 23  IIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACGS 202
           I  V+CG L   C T+ G + ++G    G LG G     ++P+I+E L G  + +V+CG+
Sbjct: 400 IKSVSCGDLFTTCLTDRGIIMTFGSGSNGCLGHGNFNDVTQPKIVEALLGYELVQVSCGA 459

Query: 203 AHTLAWT 223
           +H LA T
Sbjct: 460 SHVLAVT 466

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 27/72 (37%), Positives = 40/72 (55%)
 Frame = +2

Query: 2   AQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGI 181
           A LN +KI+ +  G+ H +  TE G+ +++G N  GQLG     ++  P  +  L  +GI
Sbjct: 563 APLNTEKIVYIDIGTAHSVAVTEKGQCFTFGSNQHGQLGCSHRRSSRVPYQVSGL--QGI 620

Query: 182 NRVACGSAHTLA 217
              ACG A TLA
Sbjct: 621 TMAACGDAFTLA 632

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 20/60 (33%), Positives = 34/60 (56%)
 Frame = +2

Query: 20  KIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACG 199
           +++ V+CG+ H +  T + EV+SWG  D G+LG  T  +++ P+ +         RV CG
Sbjct: 451 ELVQVSCGASHVLAVTNEREVFSWGRGDNGRLGLATQDSHNCPQQVSLPADFEAQRVLCG 510

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 12/28 (42%), Positives = 16/28 (57%)
 Frame = +2

Query: 35  ACGSLHCICCTEDGEVYSWGDNDEGQLG 118
           ACG    +    +GEVY+WG    G+LG
Sbjct: 624 ACGDAFTLAIGAEGEVYTWGKGARGRLG 651
>sp|Q9N1T2|RPGR_CANFA X-linked retinitis pigmentosa GTPase regulator
          Length = 1003

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 27/72 (37%), Positives = 41/72 (56%)
 Frame = +2

Query: 11  NRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRV 190
           +++KI  ++ GS      TEDGE++ WGDN EGQ+G    T    P+  +   GK I+ +
Sbjct: 138 SQRKIKQLSAGSNTSAALTEDGELFMWGDNSEGQIGLENVTNVCVPQ--QVTVGKPISWI 195

Query: 191 ACGSAHTLAWTT 226
           +CG  H+   TT
Sbjct: 196 SCGYYHSAFVTT 207

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 23/64 (35%), Positives = 37/64 (57%)
 Frame = +2

Query: 32  VACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKGINRVACGSAHT 211
           ++CG  H    T + ++Y +G N+ GQLG G+ +T S+P  ++ L  + +   ACG  HT
Sbjct: 40  LSCGDEHTAVVTGNNKLYMFGSNNWGQLGLGSKSTVSKPTCVKALKPEKVKFAACGRNHT 99

Query: 212 LAWT 223
           L  T
Sbjct: 100 LVST 103

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
 Frame = +2

Query: 8   LNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTG-KGIN 184
           L  +K+   ACG  H +  TE G+VY+ G N+EGQLG G T   S   +I   T  + I 
Sbjct: 84  LKPEKVKFAACGRNHTLVSTEGGKVYAAGGNNEGQLGLGDTEERSTFHLISFFTSQRKIK 143

Query: 185 RVACGSAHTLAWT 223
           +++ GS  + A T
Sbjct: 144 QLSAGSNTSAALT 156

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 27/65 (41%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
 Frame = +2

Query: 20  KIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTT-TNSRPRIIETLTGKGINRVAC 196
           K++ VACG  H +  TE   VY++G    GQLG GT     S P+ IE +  + I+ +AC
Sbjct: 244 KVVQVACGGGHTVVLTEKA-VYTFGLGQFGQLGLGTFLFETSVPKAIEHIKDQKISFIAC 302

Query: 197 GSAHT 211
           G  HT
Sbjct: 303 GENHT 307

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
 Frame = +2

Query: 17  KKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIETLTGKG----IN 184
           +KI  +ACG  H    T+ G +Y++GD   G+LG G    NS  + I TL        + 
Sbjct: 295 QKISFIACGENHTALITDMGLMYTFGDGRHGKLGLG--LENSTNQFIPTLCSNFLRFIVQ 352

Query: 185 RVACGSAHTLAWTTVSGNKSHETESPE 265
            V+CG  HTL + T     + E E  E
Sbjct: 353 LVSCGGCHTLVFATPRLGGTEEMELKE 379

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
 Frame = +2

Query: 17  KKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLG--DGTTTTNSRPRIIETLTGKGINRV 190
           K I  ++CG  H    T +G++Y++G+ + G+LG  +     +  P+ +  + GK + +V
Sbjct: 190 KPISWISCGYYHSAFVTTEGQLYTFGEPECGKLGLPNQLLVNHRMPQPVPGIPGKVV-QV 248

Query: 191 ACGSAHTLAWT 223
           ACG  HT+  T
Sbjct: 249 ACGGGHTVVLT 259
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,914,070
Number of Sequences: 369166
Number of extensions: 2038719
Number of successful extensions: 5649
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5280
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5627
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8534739105
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)