Planaria EST Database


DrC_02970

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02970
         (700 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9UBQ7|GRHPR_HUMAN  Glyoxylate reductase/hydroxypyruvate ...   205   8e-53
sp|Q91Z53|GRHPR_MOUSE  Glyoxylate reductase/hydroxypyruvate ...   203   3e-52
sp|O32264|TKRA_BACSU  Probable 2-ketogluconate reductase (2KR)    139   7e-33
sp|Q9C4M5|GYAR_THELI  Glyoxylate reductase (Glycolate reduct...   133   5e-31
sp|P58220|TKRA_ECO57  2-ketogluconate reductase (2KR) (2-ket...   132   1e-30
sp|P37666|TKRA_ECOLI  2-ketogluconate reductase (2KR) (2-ket...   132   1e-30
sp|O58320|GYAR_PYRHO  Glyoxylate reductase (Glycolate reduct...   129   1e-29
sp|Q9UYR1|GYAR_PYRAB  Glyoxylate reductase (Glycolate reduct...   127   2e-29
sp|Q8U3Y2|GYAR_PYRFU  Glyoxylate reductase (Glycolate reduct...   125   1e-28
sp|Q5JEZ2|GYAR_PYRKO  Glyoxylate reductase (Glycolate reduct...   123   5e-28
>sp|Q9UBQ7|GRHPR_HUMAN Glyoxylate reductase/hydroxypyruvate reductase
          Length = 328

 Score =  205 bits (522), Expect = 8e-53
 Identities = 104/204 (50%), Positives = 136/204 (66%)
 Frame = +1

Query: 4   VYSVKEGSWGAWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDTQA 183
           +  VK G W +WKP  +CGYGL  S VGI+GLG IG+AIA+R+  FG ++ L +G   + 
Sbjct: 130 IEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP 189

Query: 184 KFSQVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFVNIS 363
           +    E +       V+  EL   SDF++V+C L+  T  L N + F KMK+  +F+NIS
Sbjct: 190 E-EAAEFQAEF----VSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244

Query: 364 RGLVVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFETRNE 543
           RG VV+QD LY+AL+  +IA AGLDV+ PEPLP +HPLL L NCVILPHIG AT  TRN 
Sbjct: 245 RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNT 304

Query: 544 MCRVAVENVIKGLQGEEMISELKL 615
           M  +A  N++ GL+GE M SELKL
Sbjct: 305 MSLLAANNLLAGLRGEPMPSELKL 328
>sp|Q91Z53|GRHPR_MOUSE Glyoxylate reductase/hydroxypyruvate reductase
          Length = 328

 Score =  203 bits (517), Expect = 3e-52
 Identities = 106/207 (51%), Positives = 134/207 (64%), Gaps = 3/207 (1%)
 Frame = +1

Query: 4   VYSVKEGSWGAWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDT-- 177
           +  VK G W +W P  MCGYGL  S VGIVGLG IG+AIA+R+  FG ++ L +G     
Sbjct: 130 IEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRP 189

Query: 178 -QAKFSQVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFV 354
            +A   Q E  P          +L   SDF++VSC L+  T  L + + F KMK   IF+
Sbjct: 190 QEAAEFQAEFVP--------IAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFI 241

Query: 355 NISRGLVVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFET 534
           NISRG VV+Q+ LY+AL+  +IA AGLDV+ PEPLP  HPLL L NCVILPHIG AT++T
Sbjct: 242 NISRGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKT 301

Query: 535 RNEMCRVAVENVIKGLQGEEMISELKL 615
           RN M  +A  N++ GL+GE M SELKL
Sbjct: 302 RNTMSLLAANNLLAGLRGEAMPSELKL 328
>sp|O32264|TKRA_BACSU Probable 2-ketogluconate reductase (2KR)
          Length = 325

 Score =  139 bits (350), Expect = 7e-33
 Identities = 75/193 (38%), Positives = 112/193 (58%)
 Frame = +1

Query: 13  VKEGSWGAWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDTQAKFS 192
           V+ G WG  +   + G  + +  +GI+G+G IG+  A+R       ++L        +  
Sbjct: 128 VRAGKWGTVEEEALFGIDVHHQTLGIIGMGRIGEQAARRAKFGFDMEVLYHN-----RHR 182

Query: 193 QVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFVNISRGL 372
           + E E ++ V     D LLE SDF+++   L+D+T ++  +  F  MK + IFVNISRG 
Sbjct: 183 KQETEDSIGVKYAELDTLLEQSDFILLITPLTDETYHMIGEREFKLMKNSAIFVNISRGK 242

Query: 373 VVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFETRNEMCR 552
            VD+ +L RAL E  I GAGLDV   EP+  D+PLL+L N  +LPHIG AT + R  MC+
Sbjct: 243 TVDEKALIRALQEGWIRGAGLDVYEKEPVTQDNPLLQLDNVTLLPHIGSATAKVRFNMCK 302

Query: 553 VAVENVIKGLQGE 591
            A EN++  +QG+
Sbjct: 303 QAAENMLAAIQGQ 315
>sp|Q9C4M5|GYAR_THELI Glyoxylate reductase (Glycolate reductase)
          Length = 331

 Score =  133 bits (334), Expect = 5e-31
 Identities = 79/197 (40%), Positives = 106/197 (53%), Gaps = 4/197 (2%)
 Frame = +1

Query: 13  VKEGSWG----AWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDTQ 180
           V+ G W      W P    GYGL+   +GIVG G IG+A+AKR   FG K I  S     
Sbjct: 126 VRSGEWKKSEVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAKRAKGFGMKIIYYS----- 180

Query: 181 AKFSQVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFVNI 360
            +  + E E  +    V F+ LL+ SDF+ +   L+ +T ++  +     MK N I +N 
Sbjct: 181 -RTRKPEAEEEIGAEYVDFETLLKESDFISLHVPLTKETYHMIGEKELKLMKPNAILINT 239

Query: 361 SRGLVVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFETRN 540
           SRG VVD ++L +AL E  IAGAGLDV   EP   +  L KL N V+ PHIG AT E R 
Sbjct: 240 SRGAVVDTNALIKALKEGWIAGAGLDVFEEEPY-YNEELFKLKNVVLAPHIGSATHEARE 298

Query: 541 EMCRVAVENVIKGLQGE 591
            M  +  +N+I   +GE
Sbjct: 299 GMAELVAKNLIAFAKGE 315
>sp|P58220|TKRA_ECO57 2-ketogluconate reductase (2KR) (2-ketoaldonate reductase)
          Length = 324

 Score =  132 bits (331), Expect = 1e-30
 Identities = 81/193 (41%), Positives = 107/193 (55%)
 Frame = +1

Query: 13  VKEGSWGAWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDTQAKFS 192
           VK G W A       G  + +  +GIVG+G IG A+A+R +      IL +     A+  
Sbjct: 125 VKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYN-----ARRH 179

Query: 193 QVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFVNISRGL 372
             E E          D LL+ SDFV +   L+D+T +LF    F+KMK + IF+N  RG 
Sbjct: 180 HKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGP 239

Query: 373 VVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFETRNEMCR 552
           VVD+++L  AL +  I  AGLDV   EPL VD PLL + N V +PHIG AT ETR  M  
Sbjct: 240 VVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAA 299

Query: 553 VAVENVIKGLQGE 591
            AV+N+I  LQG+
Sbjct: 300 CAVDNLIDALQGK 312
>sp|P37666|TKRA_ECOLI 2-ketogluconate reductase (2KR) (2-ketoaldonate reductase)
          Length = 324

 Score =  132 bits (331), Expect = 1e-30
 Identities = 81/193 (41%), Positives = 107/193 (55%)
 Frame = +1

Query: 13  VKEGSWGAWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDTQAKFS 192
           VK G W A       G  + +  +GIVG+G IG A+A+R +      IL +     A+  
Sbjct: 125 VKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYN-----ARRH 179

Query: 193 QVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFVNISRGL 372
             E E          D LL+ SDFV +   L+D+T +LF    F+KMK + IF+N  RG 
Sbjct: 180 HKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGP 239

Query: 373 VVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFETRNEMCR 552
           VVD+++L  AL +  I  AGLDV   EPL VD PLL + N V +PHIG AT ETR  M  
Sbjct: 240 VVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAA 299

Query: 553 VAVENVIKGLQGE 591
            AV+N+I  LQG+
Sbjct: 300 CAVDNLIDALQGK 312
>sp|O58320|GYAR_PYRHO Glyoxylate reductase (Glycolate reductase)
          Length = 334

 Score =  129 bits (323), Expect = 1e-29
 Identities = 76/197 (38%), Positives = 108/197 (54%), Gaps = 4/197 (2%)
 Frame = +1

Query: 13  VKEGSWG----AWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDTQ 180
           V+ G W     AW P    GY +    +GI+GLG IG+AIAKR   F  + +  S +  +
Sbjct: 126 VRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNMRILYYSRTRKE 185

Query: 181 AKFSQVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFVNI 360
                 E+E  +       ++LL  SDFV+++  L+ +T +L N+     MKK  I +NI
Sbjct: 186 ------EVERELNAEFKPLEDLLRESDFVVLAVPLTRETYHLINEERLKLMKKTAILINI 239

Query: 361 SRGLVVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFETRN 540
           +RG VVD ++L +AL E  IAGAGLDV   EP   +  L KL N V+ PHIG A+F  R 
Sbjct: 240 ARGKVVDTNALVKALKEGWIAGAGLDVFEEEPY-YNEELFKLDNVVLTPHIGSASFGARE 298

Query: 541 EMCRVAVENVIKGLQGE 591
            M  +  +N+I   +GE
Sbjct: 299 GMAELVAKNLIAFKRGE 315
>sp|Q9UYR1|GYAR_PYRAB Glyoxylate reductase (Glycolate reductase)
          Length = 335

 Score =  127 bits (320), Expect = 2e-29
 Identities = 73/196 (37%), Positives = 105/196 (53%), Gaps = 4/196 (2%)
 Frame = +1

Query: 16  KEGSWG----AWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDTQA 183
           + G W     AW P    GY +    +GI+G G IG+AIAKR   F  + +  S      
Sbjct: 128 RSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGFGRIGQAIAKRARGFDMRILYYS------ 181

Query: 184 KFSQVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFVNIS 363
           +  + E+E  +       DELL  SDFV+++  L+ +T ++ N+     MK+  I +N++
Sbjct: 182 RTRKPEVEKELNAEFKPLDELLRESDFVVLAVPLNKETYHMINEERLKMMKRTAILINVA 241

Query: 364 RGLVVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFETRNE 543
           RG V+D  +L +AL E  IAGAGLDV   EP   +  L  L N V+ PHIG ATF  R  
Sbjct: 242 RGKVIDTKALIKALKEGWIAGAGLDVYEEEPY-YNEELFSLDNVVLTPHIGSATFGAREG 300

Query: 544 MCRVAVENVIKGLQGE 591
           M ++  EN+I   +GE
Sbjct: 301 MAKLVAENLIAFKRGE 316
>sp|Q8U3Y2|GYAR_PYRFU Glyoxylate reductase (Glycolate reductase)
          Length = 336

 Score =  125 bits (314), Expect = 1e-28
 Identities = 79/197 (40%), Positives = 105/197 (53%), Gaps = 4/197 (2%)
 Frame = +1

Query: 13  VKEGSWG----AWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDTQ 180
           V+ G W     AW P    GY L    +GIVG G IG+AIA+R   F  + +  S    +
Sbjct: 126 VRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRAKGFNMRILYYS----R 181

Query: 181 AKFSQVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFVNI 360
            + SQ E E       +  +E+L+ SDFVI++  L+ +T  + N+     MK   I VNI
Sbjct: 182 TRKSQAEKELGAEYRPL--EEVLKESDFVILAVPLTKETMYMINEERLKLMKPTAILVNI 239

Query: 361 SRGLVVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFETRN 540
           +RG VVD  +L +AL E  IAGAGLDV   EP   +  L  L N V+ PHIG ATFE R 
Sbjct: 240 ARGKVVDTKALIKALKEGWIAGAGLDVFEEEPY-YNEELFSLDNVVLTPHIGSATFEARE 298

Query: 541 EMCRVAVENVIKGLQGE 591
            M  +   N+I   +GE
Sbjct: 299 AMAELVARNLIAFKRGE 315
>sp|Q5JEZ2|GYAR_PYRKO Glyoxylate reductase (Glycolate reductase)
          Length = 333

 Score =  123 bits (308), Expect = 5e-28
 Identities = 74/196 (37%), Positives = 103/196 (52%), Gaps = 4/196 (2%)
 Frame = +1

Query: 16  KEGSWG----AWKPFGMCGYGLQNSVVGIVGLGNIGKAIAKRVNSFGAKKILASGSDTQA 183
           + G W     AW P    GY +    +GIVG G IG+A+A+R   FG + +  S S    
Sbjct: 127 RSGEWKRRGIAWHPRWFLGYDVYGKTIGIVGFGRIGQAVARRARGFGMRILYYSRS---- 182

Query: 184 KFSQVEIEPNVIVHKVAFDELLENSDFVIVSCLLSDKTRNLFNDNAFSKMKKNCIFVNIS 363
              + E E  +     + ++LL  SDFV+++  L+ +T+ + N+     MKK  I VNI+
Sbjct: 183 --RKPEAEKELGAEFRSLEDLLRESDFVVLAVPLTKETQYMINEERLRLMKKTAILVNIA 240

Query: 364 RGLVVDQDSLYRALSEERIAGAGLDVSVPEPLPVDHPLLKLHNCVILPHIGGATFETRNE 543
           RG VVD  +L +AL E  IAGAGLDV   EP   +  L  L N V+ PHIG AT+  R  
Sbjct: 241 RGKVVDTKALMKALKEGWIAGAGLDVYEEEPY-YNEELFSLKNVVLAPHIGSATYGAREG 299

Query: 544 MCRVAVENVIKGLQGE 591
           M  +   N+I    GE
Sbjct: 300 MAELVARNLIAFKNGE 315
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,097,122
Number of Sequences: 369166
Number of extensions: 1546939
Number of successful extensions: 5106
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4799
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4992
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6073541875
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)