Planaria EST Database


DrC_02967

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02967
         (742 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9V7Y2|SGPL_DROME  Sphingosine-1-phosphate lyase (SP-lyas...   231   2e-60
sp|Q8CHN6|SGPL1_RAT  Sphingosine-1-phosphate lyase 1 (SP-lya...   217   3e-56
sp|O95470|SGPL1_HUMAN  Sphingosine-1-phosphate lyase 1 (SP-l...   215   1e-55
sp|Q8R0X7|SGPL1_MOUSE  Sphingosine-1-phosphate lyase 1 (SP-l...   214   1e-55
sp|Q9C509|SGPL_ARATH  Sphingosine-1-phosphate lyase (SP-lyas...   178   1e-44
sp|Q05567|SGPL_YEAST  Sphingosine-1-phosphate lyase (SP-lyas...   178   1e-44
sp|Q9Y194|SGPL_CAEEL  Sphingosine-1-phosphate lyase (SP-lyas...   156   5e-38
sp|Q5JJ82|MFNA_PYRKO  L-tyrosine decarboxylase (TDC)               70   5e-12
sp|Q9UZD5|MFNA_PYRAB  L-tyrosine decarboxylase (TDC)               66   1e-10
sp|Q8U1P6|MFNA_PYRFU  L-tyrosine decarboxylase (TDC)               65   2e-10
>sp|Q9V7Y2|SGPL_DROME Sphingosine-1-phosphate lyase (SP-lyase) (SPL)
           (Sphingosine-1-phosphate aldolase)
          Length = 545

 Score =  231 bits (589), Expect = 2e-60
 Identities = 109/209 (52%), Positives = 142/209 (67%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           IS DTHKYGFAPKGSSV+LY   +Y  HQ  V  DWPGGVY SPT  GSR G IIA CW+
Sbjct: 336 ISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYGSPTVNGSRAGGIIAACWA 395

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAIKNIPGLYVLGDPKVCVVSIASDEINVYNLLDG 362
           TMM FGY GY+++T+ IV T   I   +++I G+++ G P   V+++ S+  +++ L D 
Sbjct: 396 TMMSFGYDGYLEATKRIVDTARYIERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDS 455

Query: 363 LRKCGWQLNPLQFPLSIHIAVTHIHCKKGVADKFIQDVKKETALLMKLPGPINEGSAAIY 542
           L K GW LN LQFP  IH+ VT +H + GVADKFI DV+  TA +MK PG    G  A+Y
Sbjct: 456 LCKLGWNLNALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMKDPGQPVVGKMALY 515

Query: 543 GMAQSIPDRSLVSDIAAAFIAACYSTKNQ 629
           GMAQSIPDRS++ ++   F+ + Y T +Q
Sbjct: 516 GMAQSIPDRSVIGEVTRLFLHSMYYTPSQ 544
>sp|Q8CHN6|SGPL1_RAT Sphingosine-1-phosphate lyase 1 (SP-lyase) (SPL)
           (Sphingosine-1-phosphate aldolase)
          Length = 568

 Score =  217 bits (552), Expect = 3e-56
 Identities = 95/206 (46%), Positives = 146/206 (70%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           IS DTHKYG+APKGSSVV+Y + +Y  +Q FV  DW GG+YASP+ AGSRPG IIA CW+
Sbjct: 347 ISADTHKYGYAPKGSSVVMYSNEKYRKYQFFVDADWQGGIYASPSIAGSRPGGIIAACWA 406

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAIKNIPGLYVLGDPKVCVVSIASDEINVYNLLDG 362
            +M FG  GYV++T++I++T   ++  ++NI  +++LGDP++ V+++ S++ ++Y L + 
Sbjct: 407 ALMHFGENGYVEATKQIIKTARFLKSELENIKNIFILGDPQLSVIALGSNDFDIYRLSNM 466

Query: 363 LRKCGWQLNPLQFPLSIHIAVTHIHCKKGVADKFIQDVKKETALLMKLPGPINEGSAAIY 542
           +   GW  N LQFP SIH  +T +H +K VA +F++D+++    +MK P     G  AIY
Sbjct: 467 MSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIY 526

Query: 543 GMAQSIPDRSLVSDIAAAFIAACYST 620
           GMAQ+  DR +V++I++ F+ + YST
Sbjct: 527 GMAQATIDRKMVAEISSVFLDSLYST 552
>sp|O95470|SGPL1_HUMAN Sphingosine-1-phosphate lyase 1 (SP-lyase) (hSPL)
           (Sphingosine-1-phosphate aldolase)
          Length = 568

 Score =  215 bits (547), Expect = 1e-55
 Identities = 95/206 (46%), Positives = 146/206 (70%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           IS DTHKYG+APKGSS+VLY   +Y ++Q FV  DW GG+YASPT AGSRPG I A CW+
Sbjct: 347 ISADTHKYGYAPKGSSLVLYSDKKYRNYQFFVDTDWQGGIYASPTIAGSRPGGISAACWA 406

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAIKNIPGLYVLGDPKVCVVSIASDEINVYNLLDG 362
            +M FG  GYV++T++I++T   ++  ++NI G++V G+P++ V+++ S + ++Y L + 
Sbjct: 407 ALMHFGENGYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNL 466

Query: 363 LRKCGWQLNPLQFPLSIHIAVTHIHCKKGVADKFIQDVKKETALLMKLPGPINEGSAAIY 542
           +   GW LN LQFP SIH  +T +H +K VA +F++D+++    +MK P     G  AIY
Sbjct: 467 MTAKGWNLNQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIY 526

Query: 543 GMAQSIPDRSLVSDIAAAFIAACYST 620
           GMAQ+  DR++V+++++ F+ + YST
Sbjct: 527 GMAQTTVDRNMVAELSSVFLDSLYST 552
>sp|Q8R0X7|SGPL1_MOUSE Sphingosine-1-phosphate lyase 1 (SP-lyase) (mSPL)
           (Sphingosine-1-phosphate aldolase)
          Length = 568

 Score =  214 bits (546), Expect = 1e-55
 Identities = 95/206 (46%), Positives = 145/206 (70%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           IS DTHKYG+APKGSSVV+Y + +Y ++Q FV  DW GGVYASP+ AGSRPG IIA CW+
Sbjct: 347 ISADTHKYGYAPKGSSVVMYSNEKYRTYQFFVGADWQGGVYASPSIAGSRPGGIIAACWA 406

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAIKNIPGLYVLGDPKVCVVSIASDEINVYNLLDG 362
            +M FG  GYV++T++I++T   ++  ++NI  +++ GDP++ V+++ S++ ++Y L + 
Sbjct: 407 ALMHFGENGYVEATKQIIKTARFLKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNM 466

Query: 363 LRKCGWQLNPLQFPLSIHIAVTHIHCKKGVADKFIQDVKKETALLMKLPGPINEGSAAIY 542
           +   GW  N LQFP SIH  +T +H +K VA +F++D+++    +MK P     G  AIY
Sbjct: 467 MSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIY 526

Query: 543 GMAQSIPDRSLVSDIAAAFIAACYST 620
           GMAQ+  DR LV++I++ F+   Y+T
Sbjct: 527 GMAQATIDRKLVAEISSVFLDCLYTT 552
>sp|Q9C509|SGPL_ARATH Sphingosine-1-phosphate lyase (SP-lyase) (SPL)
           (Sphingosine-1-phosphate aldolase)
          Length = 544

 Score =  178 bits (452), Expect = 1e-44
 Identities = 83/204 (40%), Positives = 128/204 (62%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           IS D HKYG APKG+S VLYR+HE   HQ     +W GG+Y SPT AGSRPG ++A  W+
Sbjct: 343 ISVDVHKYGLAPKGTSTVLYRNHEIRKHQFVAVTEWSGGLYVSPTIAGSRPGSLVAGAWA 402

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAIKNIPGLYVLGDPKVCVVSIASDEINVYNLLDG 362
            MM  G +GY+ +T +I++ + ++ + ++ I  L+V+G P + +V+  S  ++++ + D 
Sbjct: 403 AMMSLGEEGYLQNTSKIMEASKRLEEGVREIHELFVIGKPDMTIVAFGSKALDIFEVNDI 462

Query: 363 LRKCGWQLNPLQFPLSIHIAVTHIHCKKGVADKFIQDVKKETALLMKLPGPINEGSAAIY 542
           +   GW LN LQ P SIHI +T  H    V D F++D+++    +   PGPI  G A IY
Sbjct: 463 MSSKGWHLNALQRPNSIHICITLQHVP--VVDDFLRDLREAVETVKANPGPITGGLAPIY 520

Query: 543 GMAQSIPDRSLVSDIAAAFIAACY 614
           G A  +PDR +V+++  +F+ + Y
Sbjct: 521 GAAGKMPDRGMVNELLVSFMDSQY 544
>sp|Q05567|SGPL_YEAST Sphingosine-1-phosphate lyase (SP-lyase) (ySPL)
           (Sphingosine-1-phosphate aldolase) (Bestowed of
           sphingosine tolerance 1)
          Length = 589

 Score =  178 bits (452), Expect = 1e-44
 Identities = 89/208 (42%), Positives = 131/208 (62%), Gaps = 4/208 (1%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           ISCDTHKYGFAPKGSSV++YR+ +   HQ +V P W GG+Y SPT AGSRPG I+  CW+
Sbjct: 374 ISCDTHKYGFAPKGSSVIMYRNSDLRMHQYYVNPAWTGGLYGSPTLAGSRPGAIVVGCWA 433

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAI-KNIPGLYVLGDPKVCVVSIASDEINVYNLLD 359
           TM+  G  GY++S +EIV   +K +  I +NIP L ++G+P+  V+S +S  +N++ L D
Sbjct: 434 TMVNMGENGYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSD 493

Query: 360 GLRKCGWQLNPLQFPLSIHIAVTHIHCKKGVADKFIQDVKKETALLMKLPG---PINEGS 530
            L K GW  N LQ P+++H+A T +     V D+ I D+ + T   +K      P  +G+
Sbjct: 494 RLSKKGWHFNALQKPVALHMAFTRLSAH--VVDE-ICDILRTTVQELKSESNSKPSPDGT 550

Query: 531 AAIYGMAQSIPDRSLVSDIAAAFIAACY 614
           +A+YG+A S+    +   +   F+ A Y
Sbjct: 551 SALYGVAGSVKTAGVADKLIVGFLDALY 578
>sp|Q9Y194|SGPL_CAEEL Sphingosine-1-phosphate lyase (SP-lyase) (SPL)
           (Sphingosine-1-phosphate aldolase)
          Length = 552

 Score =  156 bits (395), Expect = 5e-38
 Identities = 85/206 (41%), Positives = 120/206 (58%), Gaps = 1/206 (0%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           ISCDTHKYG  PKGSS+V+YRS E    Q F   DW GG+YA+PT AGSR G   A  W+
Sbjct: 341 ISCDTHKYGCTPKGSSIVMYRSKELHHFQYFSVADWCGGIYATPTIAGSRAGANTAVAWA 400

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAIKNIPGLYVLGDPKVCVVSIASDEINVYNLLDG 362
           T++ FG   YV    +IV+ T  + + I+ I  +   G   V +V+ + + +N+Y + D 
Sbjct: 401 TLLSFGRDEYVRRCAQIVKHTRMLAEKIEKIKWIKPYGKSDVSLVAFSGNGVNIYEVSDK 460

Query: 363 LRKCGWQLNPLQFPLSIHIAVTHIHCKKGVADKFIQDVKKE-TALLMKLPGPINEGSAAI 539
           + K GW LN LQ P +IHI +T     + V + F  D++K    L  K     + G AA+
Sbjct: 461 MMKLGWNLNTLQNPAAIHICLTINQANEEVVNAFAVDLEKICEELAAKGEQKADSGMAAM 520

Query: 540 YGMAQSIPDRSLVSDIAAAFIAACYS 617
           YGMA  +P +S+V ++ A +I A YS
Sbjct: 521 YGMAAQVP-KSVVDEVIALYIDATYS 545
>sp|Q5JJ82|MFNA_PYRKO L-tyrosine decarboxylase (TDC)
          Length = 384

 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 40/160 (25%), Positives = 79/160 (49%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           I+ D HK G  P  +  +++R  ++L     + P   GG     T  G+RPG      W+
Sbjct: 225 ITIDPHKMGMVPIPAGGIIFREKKFLDSISVLAPYLAGGKIWQATITGTRPGANALAVWA 284

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAIKNIPGLYVLGDPKVCVVSIASDEINVYNLLDG 362
            +   G+ GY +  +E ++        +K IPG+Y++ +P + +VS  S+++    L   
Sbjct: 285 MIKHLGFDGYKEVVKEKMELARWFASELKKIPGIYLIREPVLNIVSFGSEKLE--ELEKE 342

Query: 363 LRKCGWQLNPLQFPLSIHIAVTHIHCKKGVADKFIQDVKK 482
           L+  GW ++  +  + I   V   H K+   ++F++D+++
Sbjct: 343 LKARGWGVSAHRGYIRI---VVMPHVKREHLEEFLRDLRE 379
>sp|Q9UZD5|MFNA_PYRAB L-tyrosine decarboxylase (TDC)
          Length = 384

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 38/160 (23%), Positives = 81/160 (50%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           I+ D HK G AP  +  +++R  +YL     + P   GG     T  G+RPG  +   W+
Sbjct: 227 ITIDPHKMGMAPIPAGGIIFRRKKYLKAISVLAPYLAGGKVWQATITGTRPGASVLAVWA 286

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAIKNIPGLYVLGDPKVCVVSIASDEINVYNLLDG 362
            +   G++GY +  R+ ++ +    + IK +   +++ +P + +VS  +   N+  +   
Sbjct: 287 LIKHLGFEGYREIVRKAMELSRWFAEEIKKLNNAWLVREPMLNIVSFQTK--NLRKVERE 344

Query: 363 LRKCGWQLNPLQFPLSIHIAVTHIHCKKGVADKFIQDVKK 482
           L++ GW ++  +  + I   V   H  K + ++F++D+++
Sbjct: 345 LKRRGWGISAHRGYIRI---VFMPHVTKEMVEEFLRDLRE 381
>sp|Q8U1P6|MFNA_PYRFU L-tyrosine decarboxylase (TDC)
          Length = 371

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 38/149 (25%), Positives = 72/149 (48%)
 Frame = +3

Query: 3   ISCDTHKYGFAPKGSSVVLYRSHEYLSHQIFVQPDWPGGVYASPTFAGSRPGVIIATCWS 182
           I+ D HK G AP  +  +++R  +YL     + P   GG     T  G+RPG  +   W+
Sbjct: 226 ITIDPHKMGMAPIPAGGIVFRHKKYLRAISVLAPYLAGGKIWQATITGTRPGASVLAVWA 285

Query: 183 TMMFFGYKGYVDSTREIVQTTIKIRDAIKNIPGLYVLGDPKVCVVSIASDEINVYNLLDG 362
            +   G++GY++     ++ +    + IK  PG +++ +P + +VS  +   N+  +   
Sbjct: 286 LIKHLGFEGYMEIVDRAMKLSRWFAEEIKKTPGAWLVREPMLNIVSFKTK--NLRRVERE 343

Query: 363 LRKCGWQLNPLQFPLSIHIAVTHIHCKKG 449
           L+  GW ++  +  + I   V+H  C  G
Sbjct: 344 LKSRGWGISAHRGYIRI---VSHASCDGG 369
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,483,223
Number of Sequences: 369166
Number of extensions: 1681572
Number of successful extensions: 4028
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3921
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4013
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6679696800
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)