Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02951 (769 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q19503|HM40_CAEEL Homeobox protein ceh-40 55 2e-07 sp|Q9BYU1|PBX4_HUMAN Pre-B-cell leukemia transcription fact... 52 1e-06 sp|P41779|HM20_CAEEL Homeobox protein ceh-20 51 4e-06 sp|Q99NE9|PBX4_MOUSE Pre-B-cell leukemia transcription fact... 51 4e-06 sp|P41778|PBX1_MOUSE Pre-B-cell leukemia transcription fact... 50 7e-06 sp|P46640|KNAT2_ARATH Homeobox protein knotted-1-like 2 (KN... 50 9e-06 sp|P40426|PBX3_HUMAN Pre-B-cell leukemia transcription fact... 49 1e-05 sp|O35317|PBX3_MOUSE Pre-B-cell leukemia transcription fact... 49 1e-05 sp|O14770|MEIS2_HUMAN Homeobox protein Meis2 (Meis1-related... 48 3e-05 sp|P40427|EXD_DROME Homeobox protein extradenticle 48 3e-05
>sp|Q19503|HM40_CAEEL Homeobox protein ceh-40 Length = 329 Score = 55.5 bits (132), Expect = 2e-07 Identities = 23/76 (30%), Positives = 48/76 (63%) Frame = +2 Query: 413 LEKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMALEGKIGVSQVNSWFANRRNR 592 L+ ++K + ++++ +I+ ++ NI+ PYPS +K+ +A++ I V+QV++WF N+R R Sbjct: 185 LDARRKRRNFSKTSTEILNEYFLANINHPYPSEEVKQALAMQCNISVAQVSNWFGNKRIR 244 Query: 593 SDNTKPKKNRKQLQVR 640 T K ++ + R Sbjct: 245 YKKTMAKNEDERRENR 260
>sp|Q9BYU1|PBX4_HUMAN Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4) Length = 330 Score = 52.4 bits (124), Expect = 1e-06 Identities = 23/75 (30%), Positives = 48/75 (64%) Frame = +2 Query: 410 LLEKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMALEGKIGVSQVNSWFANRRN 589 LL+ ++K + ++ A +++ ++ ++++ PYPS K+++A +G + +SQV++WF N+R Sbjct: 163 LLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRI 222 Query: 590 RSDNTKPKKNRKQLQ 634 R KKN + Q Sbjct: 223 RY-----KKNMGKFQ 232
>sp|P41779|HM20_CAEEL Homeobox protein ceh-20 Length = 338 Score = 50.8 bits (120), Expect = 4e-06 Identities = 25/81 (30%), Positives = 46/81 (56%) Frame = +2 Query: 413 LEKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMALEGKIGVSQVNSWFANRRNR 592 L+ ++K + ++ A +++ ++ ++ PYPS K+D+A + I VSQV++WF N+R R Sbjct: 186 LDARRKRRNFSKQATEVLNEYFYGHLSNPYPSEEAKEDLARQCNITVSQVSNWFGNKRIR 245 Query: 593 SDNTKPKKNRKQLQVRLYKFA 655 KKN + Q +A Sbjct: 246 Y-----KKNMAKAQEEASMYA 261
>sp|Q99NE9|PBX4_MOUSE Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4) Length = 378 Score = 50.8 bits (120), Expect = 4e-06 Identities = 24/74 (32%), Positives = 45/74 (60%) Frame = +2 Query: 413 LEKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMALEGKIGVSQVNSWFANRRNR 592 L+ ++K + ++ A ++ ++ +++ PYPS K+++A +G I VSQV++WF N+R R Sbjct: 213 LDARRKRRNFSKQATDVLNEYFYSHLSNPYPSEETKEELARKGGITVSQVSNWFGNKRIR 272 Query: 593 SDNTKPKKNRKQLQ 634 KKN + Q Sbjct: 273 Y-----KKNTGKFQ 281
>sp|P41778|PBX1_MOUSE Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) sp|P40424|PBX1_HUMAN Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) (Homeobox protein PRL) Length = 430 Score = 50.1 bits (118), Expect = 7e-06 Identities = 21/60 (35%), Positives = 40/60 (66%) Frame = +2 Query: 413 LEKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMALEGKIGVSQVNSWFANRRNR 592 L+ ++K + N+ A +I+ ++ +++ PYPS K+++A + I VSQV++WF N+R R Sbjct: 231 LDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
>sp|P46640|KNAT2_ARATH Homeobox protein knotted-1-like 2 (KNAT2) (ATK1) Length = 310 Score = 49.7 bits (117), Expect = 9e-06 Identities = 39/148 (26%), Positives = 72/148 (48%) Frame = +2 Query: 176 FLKNFDVENIKITNQTSSSTALTQSKNVIPDGDLRSIINSIKPFDTDNSQSNKTADKLIS 355 F+ +++ + +S+TAL+ V D +LR + D+SQ ++ D+ + Sbjct: 156 FINKIEMQLQNLCTGPASATALSDDGAVSSDEELREDDD----IAADDSQQ-RSNDRDLK 210 Query: 356 DSLEKIXXXXXXXXXXDFLLEKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMAL 535 D L + +F +K+KK K E+ +++ W +N +PYP+ K +A Sbjct: 211 DQLLRKFGSHISSLKLEFS-KKKKKGKLpreARQALLDWWNVHN-KWPYPTEGDKISLAE 268 Query: 536 EGKIGVSQVNSWFANRRNRSDNTKPKKN 619 E + Q+N+WF N+R R + KP +N Sbjct: 269 ETGLDQKQINNWFINQRKR--HWKPSEN 294
>sp|P40426|PBX3_HUMAN Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3) Length = 434 Score = 49.3 bits (116), Expect = 1e-05 Identities = 25/88 (28%), Positives = 50/88 (56%) Frame = +2 Query: 413 LEKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMALEGKIGVSQVNSWFANRRNR 592 L+ ++K + ++ A +I+ ++ +++ PYPS K+++A + I VSQV++WF N+R R Sbjct: 233 LDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIR 292 Query: 593 SDNTKPKKNRKQLQVRLYKFAQELEINS 676 KKN + Q +A + + + Sbjct: 293 Y-----KKNIGKFQEEANLYAAKTAVTA 315
>sp|O35317|PBX3_MOUSE Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3) Length = 434 Score = 49.3 bits (116), Expect = 1e-05 Identities = 25/88 (28%), Positives = 50/88 (56%) Frame = +2 Query: 413 LEKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMALEGKIGVSQVNSWFANRRNR 592 L+ ++K + ++ A +I+ ++ +++ PYPS K+++A + I VSQV++WF N+R R Sbjct: 233 LDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIR 292 Query: 593 SDNTKPKKNRKQLQVRLYKFAQELEINS 676 KKN + Q +A + + + Sbjct: 293 Y-----KKNIGKFQEEANLYAAKTAVTA 315
>sp|O14770|MEIS2_HUMAN Homeobox protein Meis2 (Meis1-related protein 1) Length = 477 Score = 48.1 bits (113), Expect = 3e-05 Identities = 22/59 (37%), Positives = 33/59 (55%) Frame = +2 Query: 416 EKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMALEGKIGVSQVNSWFANRRNR 592 ++QKK + A IM +W ++ PYPS KK +A + + + QVN+WF N R R Sbjct: 275 KRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333
>sp|P40427|EXD_DROME Homeobox protein extradenticle Length = 376 Score = 48.1 bits (113), Expect = 3e-05 Identities = 24/78 (30%), Positives = 46/78 (58%) Frame = +2 Query: 413 LEKQKKNKPLNESAIKIMESWYTNNIDFPYPSNAIKKDMALEGKIGVSQVNSWFANRRNR 592 L+ ++K + ++ A +I+ ++ +++ PYPS K+++A + I VSQV++WF N+R R Sbjct: 236 LDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIR 295 Query: 593 SDNTKPKKNRKQLQVRLY 646 K + Q + LY Sbjct: 296 ---YKKNIGKAQEEANLY 310
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 74,792,204 Number of Sequences: 369166 Number of extensions: 1355943 Number of successful extensions: 4775 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4621 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4768 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7115329200 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)