Planaria EST Database


DrC_02946

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02946
         (820 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9UBS8|RNF14_HUMAN  RING finger protein 14 (Androgen rece...   114   3e-25
sp|Q9JI90|RNF14_MOUSE  RING finger protein 14 (Androgen rece...   112   1e-24
sp|O76924|ARI2_DROME  Ariadne-2 protein (Ari-2)                    60   5e-09
sp|O95376|ARI2_HUMAN  Ariadne-2 protein homolog (ARI-2) (Tri...    59   2e-08
sp|Q04638|YMG8_YEAST  Hypothetical 54.1 kDa protein in DAK1-...    57   6e-08
sp|Q9Z1K6|ARI2_MOUSE  Ariadne-2 protein homolog (ARI-2) (Tri...    57   6e-08
sp|P36113|YKZ7_YEAST  Hypothetical 63.6 kDa protein in YPT52...    57   6e-08
sp|Q9Y4X5|ARI1_HUMAN  Ariadne-1 protein homolog (ARI-1) (Ubi...    54   4e-07
sp|Q9Z1K5|ARI1_MOUSE  Ariadne-1 protein homolog (ARI-1) (Ubi...    54   4e-07
sp|Q9NWF9|UB7I1_HUMAN  E3 ubiquitin ligase TRIAD3 (Ubiquitin...    51   4e-06
>sp|Q9UBS8|RNF14_HUMAN RING finger protein 14 (Androgen receptor-associated protein 54)
           (Triad2 protein) (HFB30)
          Length = 474

 Score =  114 bits (285), Expect = 3e-25
 Identities = 73/251 (29%), Positives = 110/251 (43%), Gaps = 35/251 (13%)
 Frame = +3

Query: 3   NIYEILKDFNRRKSEIVFNNTIFECSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQI 182
           N+ + + DF++ +    FN+ +F CS+C   K G  C+    C+HV+C  C  D+++ QI
Sbjct: 196 NLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQI 255

Query: 183 KS---XXXXXXXXXXXXTIEHSEIRKLMSEEEFERWDKLLLTQCLKDKKAFHSCPR--CE 347
           +                     ++++L+  E F R+D+LLL   L        CPR  C+
Sbjct: 256 RDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ 315

Query: 348 MSVVTDED-EFGICPXXXXXXXXXXNMTYHGPGKC------------------EGNE--- 461
           + V+ +     GIC            +TYHG   C                  E N+   
Sbjct: 316 LPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLL 375

Query: 462 -----KRKEKERLNQIE--EMLNEKHKRCPSCNQAYEKNGGCNKMIC-NCGVYFCFLCSK 617
                KR  ++ L ++E  E L +  K CP C    EK  GCNKM C  C  YFC++C  
Sbjct: 376 DQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435

Query: 618 ILDKFNPYNHF 650
            L + NPY HF
Sbjct: 436 SLSRANPYKHF 446
>sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen receptor-associated protein 54)
           (Triad2 protein)
          Length = 485

 Score =  112 bits (280), Expect = 1e-24
 Identities = 75/250 (30%), Positives = 110/250 (44%), Gaps = 35/250 (14%)
 Frame = +3

Query: 6   IYEILKDFNRRKSEIVFNNTIFECSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIK 185
           I EIL DFN+ +    FN+ +F CS+C   K G +C+    CKHV+C  C  D+++ QIK
Sbjct: 199 IQEIL-DFNQARQTKCFNSKLFLCSICFCEKLGSDCMYFLECKHVYCKACLKDYFEIQIK 257

Query: 186 S---XXXXXXXXXXXXTIEHSEIRKLMSEEEFERWDKLLLTQCLKDKKAFHSCPR--CEM 350
                                ++++L+  + F R+D+LLL   L        CPR  C++
Sbjct: 258 DGQVKCLNCPEPQCPSVATPGQVKELVEADLFARYDRLLLQSTLDLMADVVYCPRPCCQL 317

Query: 351 SVVTDE-DEFGICPXXXXXXXXXXNMTYHGPGKCE---------GNE------------- 461
            V+ +      IC            +TYHG   C+          NE             
Sbjct: 318 PVMQEPGGTMAICSSCNFAFCTLCRLTYHGLSPCKVTAEKLIDLRNEYLQADEATKRFLE 377

Query: 462 ----KRKEKERLNQIE--EMLNEKHKRCPSCNQAYEKNGGCNKMIC-NCGVYFCFLCSKI 620
               KR  ++ L ++E  + L +  K CP C    +K  GCNKM C  C  YFC++C   
Sbjct: 378 QRYGKRVIQKALEEMESKDWLEKNSKSCPCCGTPIQKLDGCNKMTCTGCMQYFCWICMGS 437

Query: 621 LDKFNPYNHF 650
           L + NPY HF
Sbjct: 438 LSRANPYRHF 447
>sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2)
          Length = 509

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 45/189 (23%), Positives = 71/189 (37%), Gaps = 10/189 (5%)
 Frame = +3

Query: 75  CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIK---SXXXXXXXXXXXXTIEHSEI 245
           C VC   + G     L  C H FC +C   ++++QI    S             +    +
Sbjct: 153 CPVCASSQLGDKFYSLA-CGHSFCKDCWTIYFETQIFQGISTQIGCMAQMCNVRVPEDLV 211

Query: 246 RKLMSEEEF-ERWDKLLLTQCLKDKKAFHSCPRCEMSVVTDEDEFG----ICPXXXXXXX 410
             L++     +++ +      +K       CP     ++    E      IC        
Sbjct: 212 LTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNCQIIVQSSEISAKRAICKACHTGFC 271

Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMIC-N 584
               M YH P  C+  +K   K    ++    ++   K CP C+   EKNGGCN M C N
Sbjct: 272 FRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICIEKNGGCNHMQCFN 331

Query: 585 CGVYFCFLC 611
           C   FC++C
Sbjct: 332 CKHDFCWMC 340

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +3

Query: 72  ECSVCMILKRGINCIKLENCKHVFCLECGNDF 167
           +C +C+    G N ++  NCKH FC  C  D+
Sbjct: 313 KCHICIEKNGGCNHMQCFNCKHDFCWMCLGDW 344
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
          Length = 493

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 49/189 (25%), Positives = 68/189 (35%), Gaps = 10/189 (5%)
 Frame = +3

Query: 75  CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXXXXXXXXX----TIEHSE 242
           C+VCM   R  N + L  C+H FC  C        +K                 T E   
Sbjct: 139 CAVCMQFVRKENLLSLA-CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197

Query: 243 IRKLMSEEEFERWDKLLLTQCLKDKKAFHSCPRCEMSVVTDEDEFGI----CPXXXXXXX 410
              L +EE  E++ + L    ++       CP  +  +V    E       C        
Sbjct: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFC 257

Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMICN- 584
                 YH P  C    K   K    ++    ++   K CP CN   EKNGGCN M C+ 
Sbjct: 258 FKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK 317

Query: 585 CGVYFCFLC 611
           C   FC++C
Sbjct: 318 CKHDFCWMC 326

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 11/32 (34%), Positives = 18/32 (56%)
 Frame = +3

Query: 72  ECSVCMILKRGINCIKLENCKHVFCLECGNDF 167
           +C++C+    G N ++   CKH FC  C  D+
Sbjct: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 330
>sp|Q04638|YMG8_YEAST Hypothetical 54.1 kDa protein in DAK1-ORC1 intergenic region
          Length = 464

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 58/287 (20%), Positives = 102/287 (35%), Gaps = 73/287 (25%)
 Frame = +3

Query: 9    YEILKDFNRRKSEIVFNNTIFECSVCMILKRGINCIKLE----NCKHVFCLECGN----- 161
            Y++ K  +   +    + + + C +CM +++G+  IKL     N +H  C  C       
Sbjct: 158  YDLFKQISEEATLQKVSRSNYHCCICMEMEKGVRMIKLPCENANVEHYLCRGCAKSYFTA 217

Query: 162  ---------------DFYDSQIKSXXXXXXXXXXXXT--IEHSEIRKLMSEEEFERWDKL 290
                           ++ + +++             T  I  S +++++  E  ER++K+
Sbjct: 218  MIQENRISSVRCPQCEYKELKLEDFKSYKKMLKALFTPLIPVSFLKEVIDTELCERYEKM 277

Query: 291  LLTQCLKDKKAFH-----SCPRCEMSVVTDE--DEFGICPXXXXXXXXXXNMTYHG-PGK 446
               Q       +      +C RC+     ++  D    C              +HG   K
Sbjct: 278  FYNQAATRLSKYCPYACVTCRRCDSWCTKEDLDDAMIQCQKCHFVFCFDCLHAWHGYNNK 337

Query: 447  C--------------------EGNEKRKEKERLN------QIEEMLNEKH---------- 518
            C                        KRK + +        ++ + L EK           
Sbjct: 338  CGKKVSLSTDIIEEYLDDTVTSYERKRKLEAKYGRRVLELEVNDYLAEKMLDLAIKKEGS 397

Query: 519  --KRCPSCNQAYEKNGGCNKMICN-CGVYFCFLCSKILDKFNPYNHF 650
              +RCP C    E++ GCNKM C  CG  FCF+C  +L   +PY HF
Sbjct: 398  NLQRCPKCKVVVERSEGCNKMKCEVCGTLFCFICGVLLYPEDPYEHF 444
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
           (UbcM4-interacting protein 48)
          Length = 492

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 48/189 (25%), Positives = 68/189 (35%), Gaps = 10/189 (5%)
 Frame = +3

Query: 75  CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXXXXXXXXX----TIEHSE 242
           C+VCM   R  N + L  C+H FC  C        +K                 T E   
Sbjct: 138 CAVCMQFVRKENLLSLA-CQHQFCRSCWEQHCSVLVKDGVGVGISCMAQDCPLRTPEDFV 196

Query: 243 IRKLMSEEEFERWDKLLLTQCLKDKKAFHSCPRCEMSVVTDEDEFGI----CPXXXXXXX 410
              L +EE  +++ + L    ++       CP  +  +V    E       C        
Sbjct: 197 FPLLPNEELRDKYRRYLFRDYVESHFQLQLCPGADCPMVIRVQEPRARRVQCNRCSEVFC 256

Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMICN- 584
                 YH P  C    K   K    ++    ++   K CP CN   EKNGGCN M C+ 
Sbjct: 257 FKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK 316

Query: 585 CGVYFCFLC 611
           C   FC++C
Sbjct: 317 CKHDFCWMC 325

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 11/32 (34%), Positives = 18/32 (56%)
 Frame = +3

Query: 72  ECSVCMILKRGINCIKLENCKHVFCLECGNDF 167
           +C++C+    G N ++   CKH FC  C  D+
Sbjct: 298 KCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 329
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region
          Length = 551

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 49/216 (22%), Positives = 79/216 (36%), Gaps = 20/216 (9%)
 Frame = +3

Query: 24  DFNRRKSEIVFNNTIFECSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXX 203
           D+N    E+ F N  F C +C   K+      LE C H +C+ C   +   ++       
Sbjct: 163 DYNSHFREVEFKND-FTCIICCD-KKDTETFALE-CGHEYCINCYRHYIKDKLHEGNIIT 219

Query: 204 XXXXXXXTIEHSEIRKLMSEEEFER-WDKLLLTQCLKDKKAFHSCPRCEMSVVTDEDEFG 380
                   +++ +I K+M      +  D  + +   K  + +  CP  +   +    +  
Sbjct: 220 CMDCSL-ALKNEDIDKVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTS 278

Query: 381 ICPXXXXXXXXXX-------------NMTYHGPGKCE-----GNEKRKEKERLNQIEEML 506
             P                           H P  C+       + RKE E LN +    
Sbjct: 279 SLPEYTRLHYSPFVKCNSFHRFCFNCGFEVHSPADCKITTAWVKKARKESEILNWVLSHT 338

Query: 507 NEKHKRCPSCNQAYEKNGGCNKMIC-NCGVYFCFLC 611
            E    CP C+   EKNGGCN M+C +C   FC++C
Sbjct: 339 KE----CPKCSVNIEKNGGCNHMVCSSCKYEFCWIC 370
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
           E2-binding protein 1) (UbcH7-binding protein)
           (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6)
          Length = 557

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 41/191 (21%), Positives = 80/191 (41%), Gaps = 12/191 (6%)
 Frame = +3

Query: 75  CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXXXXXXXXX----TIEHSE 242
           C +C +         LE C H FC++C +++  ++I                   ++ + 
Sbjct: 186 CQICYLNYPNSYFTGLE-CGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNT 244

Query: 243 IRKLMSEEEFE-RWDKLLLTQCLKDKKAFHSCPR--CEMSV-VTDEDEFGICPXXXXXXX 410
           + +L+++ + + ++  L+    ++  +    CP   C   V V   D   +         
Sbjct: 245 VMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFC 304

Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMIC-- 581
                 +H P KC+  +K  +K +  ++    +    K CP C+   EK+GGCN M+C  
Sbjct: 305 FNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRN 364

Query: 582 -NCGVYFCFLC 611
            NC   FC++C
Sbjct: 365 QNCKAEFCWVC 375
>sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
           E2-binding protein 1) (UbcH7-binding protein)
           (UbcM4-interacting protein 77)
          Length = 555

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 41/191 (21%), Positives = 80/191 (41%), Gaps = 12/191 (6%)
 Frame = +3

Query: 75  CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXXXXXXXXX----TIEHSE 242
           C +C +         LE C H FC++C +++  ++I                   ++ + 
Sbjct: 184 CQICYLNYPNSYFTGLE-CGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNT 242

Query: 243 IRKLMSEEEFE-RWDKLLLTQCLKDKKAFHSCPR--CEMSV-VTDEDEFGICPXXXXXXX 410
           + +L+++ + + ++  L+    ++  +    CP   C   V V   D   +         
Sbjct: 243 VMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFC 302

Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMIC-- 581
                 +H P KC+  +K  +K +  ++    +    K CP C+   EK+GGCN M+C  
Sbjct: 303 FNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRN 362

Query: 582 -NCGVYFCFLC 611
            NC   FC++C
Sbjct: 363 QNCKAEFCWVC 373
>sp|Q9NWF9|UB7I1_HUMAN E3 ubiquitin ligase TRIAD3 (Ubiquitin conjugating enzyme 7
           interacting protein 1) (Zinc finger protein inhibiting
           NF-kappa-B)
          Length = 866

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 34/117 (29%), Positives = 45/117 (38%), Gaps = 6/117 (5%)
 Frame = +3

Query: 333 CPRCEMSVVTDEDEFGI-CPXXXXXXXXXXNMT----YHGPGKCEG-NEKRKEKERLNQI 494
           CP C    + D D     CP                  H    CE   EK   K R +  
Sbjct: 605 CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIE 664

Query: 495 EEMLNEKHKRCPSCNQAYEKNGGCNKMICNCGVYFCFLCSKILDKFNPYNHFGLRPK 665
           E+M   + ++C  C     K+ GCN+M C CG   C+LC       N Y+HF   P+
Sbjct: 665 EKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRV---SINGYDHFCQHPR 718
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,203,143
Number of Sequences: 369166
Number of extensions: 1490921
Number of successful extensions: 4790
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4542
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4759
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)