Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_F07
(820 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UBS8|RNF14_HUMAN RING finger protein 14 (Androgen rece... 114 3e-25
sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen rece... 112 1e-24
sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2) 60 5e-09
sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 59 2e-08
sp|Q04638|YMG8_YEAST Hypothetical 54.1 kDa protein in DAK1-... 57 6e-08
sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 57 6e-08
sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 57 6e-08
sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 54 4e-07
sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubi... 54 4e-07
sp|Q9NWF9|UB7I1_HUMAN E3 ubiquitin ligase TRIAD3 (Ubiquitin... 51 4e-06
>sp|Q9UBS8|RNF14_HUMAN RING finger protein 14 (Androgen receptor-associated protein 54)
(Triad2 protein) (HFB30)
Length = 474
Score = 114 bits (285), Expect = 3e-25
Identities = 73/251 (29%), Positives = 110/251 (43%), Gaps = 35/251 (13%)
Frame = +3
Query: 3 NIYEILKDFNRRKSEIVFNNTIFECSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQI 182
N+ + + DF++ + FN+ +F CS+C K G C+ C+HV+C C D+++ QI
Sbjct: 196 NLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQI 255
Query: 183 KS---XXXXXXXXXXXXTIEHSEIRKLMSEEEFERWDKLLLTQCLKDKKAFHSCPR--CE 347
+ ++++L+ E F R+D+LLL L CPR C+
Sbjct: 256 RDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ 315
Query: 348 MSVVTDED-EFGICPXXXXXXXXXXNMTYHGPGKC------------------EGNE--- 461
+ V+ + GIC +TYHG C E N+
Sbjct: 316 LPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLL 375
Query: 462 -----KRKEKERLNQIE--EMLNEKHKRCPSCNQAYEKNGGCNKMIC-NCGVYFCFLCSK 617
KR ++ L ++E E L + K CP C EK GCNKM C C YFC++C
Sbjct: 376 DQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435
Query: 618 ILDKFNPYNHF 650
L + NPY HF
Sbjct: 436 SLSRANPYKHF 446
>sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen receptor-associated protein 54)
(Triad2 protein)
Length = 485
Score = 112 bits (280), Expect = 1e-24
Identities = 75/250 (30%), Positives = 110/250 (44%), Gaps = 35/250 (14%)
Frame = +3
Query: 6 IYEILKDFNRRKSEIVFNNTIFECSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIK 185
I EIL DFN+ + FN+ +F CS+C K G +C+ CKHV+C C D+++ QIK
Sbjct: 199 IQEIL-DFNQARQTKCFNSKLFLCSICFCEKLGSDCMYFLECKHVYCKACLKDYFEIQIK 257
Query: 186 S---XXXXXXXXXXXXTIEHSEIRKLMSEEEFERWDKLLLTQCLKDKKAFHSCPR--CEM 350
++++L+ + F R+D+LLL L CPR C++
Sbjct: 258 DGQVKCLNCPEPQCPSVATPGQVKELVEADLFARYDRLLLQSTLDLMADVVYCPRPCCQL 317
Query: 351 SVVTDE-DEFGICPXXXXXXXXXXNMTYHGPGKCE---------GNE------------- 461
V+ + IC +TYHG C+ NE
Sbjct: 318 PVMQEPGGTMAICSSCNFAFCTLCRLTYHGLSPCKVTAEKLIDLRNEYLQADEATKRFLE 377
Query: 462 ----KRKEKERLNQIE--EMLNEKHKRCPSCNQAYEKNGGCNKMIC-NCGVYFCFLCSKI 620
KR ++ L ++E + L + K CP C +K GCNKM C C YFC++C
Sbjct: 378 QRYGKRVIQKALEEMESKDWLEKNSKSCPCCGTPIQKLDGCNKMTCTGCMQYFCWICMGS 437
Query: 621 LDKFNPYNHF 650
L + NPY HF
Sbjct: 438 LSRANPYRHF 447
>sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2)
Length = 509
Score = 60.5 bits (145), Expect = 5e-09
Identities = 45/189 (23%), Positives = 71/189 (37%), Gaps = 10/189 (5%)
Frame = +3
Query: 75 CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIK---SXXXXXXXXXXXXTIEHSEI 245
C VC + G L C H FC +C ++++QI S + +
Sbjct: 153 CPVCASSQLGDKFYSLA-CGHSFCKDCWTIYFETQIFQGISTQIGCMAQMCNVRVPEDLV 211
Query: 246 RKLMSEEEF-ERWDKLLLTQCLKDKKAFHSCPRCEMSVVTDEDEFG----ICPXXXXXXX 410
L++ +++ + +K CP ++ E IC
Sbjct: 212 LTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNCQIIVQSSEISAKRAICKACHTGFC 271
Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMIC-N 584
M YH P C+ +K K ++ ++ K CP C+ EKNGGCN M C N
Sbjct: 272 FRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICIEKNGGCNHMQCFN 331
Query: 585 CGVYFCFLC 611
C FC++C
Sbjct: 332 CKHDFCWMC 340
Score = 31.2 bits (69), Expect = 3.6
Identities = 12/32 (37%), Positives = 18/32 (56%)
Frame = +3
Query: 72 ECSVCMILKRGINCIKLENCKHVFCLECGNDF 167
+C +C+ G N ++ NCKH FC C D+
Sbjct: 313 KCHICIEKNGGCNHMQCFNCKHDFCWMCLGDW 344
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
Length = 493
Score = 58.5 bits (140), Expect = 2e-08
Identities = 49/189 (25%), Positives = 68/189 (35%), Gaps = 10/189 (5%)
Frame = +3
Query: 75 CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXXXXXXXXX----TIEHSE 242
C+VCM R N + L C+H FC C +K T E
Sbjct: 139 CAVCMQFVRKENLLSLA-CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197
Query: 243 IRKLMSEEEFERWDKLLLTQCLKDKKAFHSCPRCEMSVVTDEDEFGI----CPXXXXXXX 410
L +EE E++ + L ++ CP + +V E C
Sbjct: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFC 257
Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMICN- 584
YH P C K K ++ ++ K CP CN EKNGGCN M C+
Sbjct: 258 FKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK 317
Query: 585 CGVYFCFLC 611
C FC++C
Sbjct: 318 CKHDFCWMC 326
Score = 30.8 bits (68), Expect = 4.7
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = +3
Query: 72 ECSVCMILKRGINCIKLENCKHVFCLECGNDF 167
+C++C+ G N ++ CKH FC C D+
Sbjct: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 330
>sp|Q04638|YMG8_YEAST Hypothetical 54.1 kDa protein in DAK1-ORC1 intergenic region
Length = 464
Score = 57.0 bits (136), Expect = 6e-08
Identities = 58/287 (20%), Positives = 102/287 (35%), Gaps = 73/287 (25%)
Frame = +3
Query: 9 YEILKDFNRRKSEIVFNNTIFECSVCMILKRGINCIKLE----NCKHVFCLECGN----- 161
Y++ K + + + + + C +CM +++G+ IKL N +H C C
Sbjct: 158 YDLFKQISEEATLQKVSRSNYHCCICMEMEKGVRMIKLPCENANVEHYLCRGCAKSYFTA 217
Query: 162 ---------------DFYDSQIKSXXXXXXXXXXXXT--IEHSEIRKLMSEEEFERWDKL 290
++ + +++ T I S +++++ E ER++K+
Sbjct: 218 MIQENRISSVRCPQCEYKELKLEDFKSYKKMLKALFTPLIPVSFLKEVIDTELCERYEKM 277
Query: 291 LLTQCLKDKKAFH-----SCPRCEMSVVTDE--DEFGICPXXXXXXXXXXNMTYHG-PGK 446
Q + +C RC+ ++ D C +HG K
Sbjct: 278 FYNQAATRLSKYCPYACVTCRRCDSWCTKEDLDDAMIQCQKCHFVFCFDCLHAWHGYNNK 337
Query: 447 C--------------------EGNEKRKEKERLN------QIEEMLNEKH---------- 518
C KRK + + ++ + L EK
Sbjct: 338 CGKKVSLSTDIIEEYLDDTVTSYERKRKLEAKYGRRVLELEVNDYLAEKMLDLAIKKEGS 397
Query: 519 --KRCPSCNQAYEKNGGCNKMICN-CGVYFCFLCSKILDKFNPYNHF 650
+RCP C E++ GCNKM C CG FCF+C +L +PY HF
Sbjct: 398 NLQRCPKCKVVVERSEGCNKMKCEVCGTLFCFICGVLLYPEDPYEHF 444
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
(UbcM4-interacting protein 48)
Length = 492
Score = 57.0 bits (136), Expect = 6e-08
Identities = 48/189 (25%), Positives = 68/189 (35%), Gaps = 10/189 (5%)
Frame = +3
Query: 75 CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXXXXXXXXX----TIEHSE 242
C+VCM R N + L C+H FC C +K T E
Sbjct: 138 CAVCMQFVRKENLLSLA-CQHQFCRSCWEQHCSVLVKDGVGVGISCMAQDCPLRTPEDFV 196
Query: 243 IRKLMSEEEFERWDKLLLTQCLKDKKAFHSCPRCEMSVVTDEDEFGI----CPXXXXXXX 410
L +EE +++ + L ++ CP + +V E C
Sbjct: 197 FPLLPNEELRDKYRRYLFRDYVESHFQLQLCPGADCPMVIRVQEPRARRVQCNRCSEVFC 256
Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMICN- 584
YH P C K K ++ ++ K CP CN EKNGGCN M C+
Sbjct: 257 FKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK 316
Query: 585 CGVYFCFLC 611
C FC++C
Sbjct: 317 CKHDFCWMC 325
Score = 30.8 bits (68), Expect = 4.7
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = +3
Query: 72 ECSVCMILKRGINCIKLENCKHVFCLECGNDF 167
+C++C+ G N ++ CKH FC C D+
Sbjct: 298 KCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 329
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region
Length = 551
Score = 57.0 bits (136), Expect = 6e-08
Identities = 49/216 (22%), Positives = 79/216 (36%), Gaps = 20/216 (9%)
Frame = +3
Query: 24 DFNRRKSEIVFNNTIFECSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXX 203
D+N E+ F N F C +C K+ LE C H +C+ C + ++
Sbjct: 163 DYNSHFREVEFKND-FTCIICCD-KKDTETFALE-CGHEYCINCYRHYIKDKLHEGNIIT 219
Query: 204 XXXXXXXTIEHSEIRKLMSEEEFER-WDKLLLTQCLKDKKAFHSCPRCEMSVVTDEDEFG 380
+++ +I K+M + D + + K + + CP + + +
Sbjct: 220 CMDCSL-ALKNEDIDKVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTS 278
Query: 381 ICPXXXXXXXXXX-------------NMTYHGPGKCE-----GNEKRKEKERLNQIEEML 506
P H P C+ + RKE E LN +
Sbjct: 279 SLPEYTRLHYSPFVKCNSFHRFCFNCGFEVHSPADCKITTAWVKKARKESEILNWVLSHT 338
Query: 507 NEKHKRCPSCNQAYEKNGGCNKMIC-NCGVYFCFLC 611
E CP C+ EKNGGCN M+C +C FC++C
Sbjct: 339 KE----CPKCSVNIEKNGGCNHMVCSSCKYEFCWIC 370
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6)
Length = 557
Score = 54.3 bits (129), Expect = 4e-07
Identities = 41/191 (21%), Positives = 80/191 (41%), Gaps = 12/191 (6%)
Frame = +3
Query: 75 CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXXXXXXXXX----TIEHSE 242
C +C + LE C H FC++C +++ ++I ++ +
Sbjct: 186 CQICYLNYPNSYFTGLE-CGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNT 244
Query: 243 IRKLMSEEEFE-RWDKLLLTQCLKDKKAFHSCPR--CEMSV-VTDEDEFGICPXXXXXXX 410
+ +L+++ + + ++ L+ ++ + CP C V V D +
Sbjct: 245 VMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFC 304
Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMIC-- 581
+H P KC+ +K +K + ++ + K CP C+ EK+GGCN M+C
Sbjct: 305 FNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRN 364
Query: 582 -NCGVYFCFLC 611
NC FC++C
Sbjct: 365 QNCKAEFCWVC 375
>sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein 77)
Length = 555
Score = 54.3 bits (129), Expect = 4e-07
Identities = 41/191 (21%), Positives = 80/191 (41%), Gaps = 12/191 (6%)
Frame = +3
Query: 75 CSVCMILKRGINCIKLENCKHVFCLECGNDFYDSQIKSXXXXXXXXXXXX----TIEHSE 242
C +C + LE C H FC++C +++ ++I ++ +
Sbjct: 184 CQICYLNYPNSYFTGLE-CGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNT 242
Query: 243 IRKLMSEEEFE-RWDKLLLTQCLKDKKAFHSCPR--CEMSV-VTDEDEFGICPXXXXXXX 410
+ +L+++ + + ++ L+ ++ + CP C V V D +
Sbjct: 243 VMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFC 302
Query: 411 XXXNMTYHGPGKCEGNEKRKEK-ERLNQIEEMLNEKHKRCPSCNQAYEKNGGCNKMIC-- 581
+H P KC+ +K +K + ++ + K CP C+ EK+GGCN M+C
Sbjct: 303 FNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRN 362
Query: 582 -NCGVYFCFLC 611
NC FC++C
Sbjct: 363 QNCKAEFCWVC 373
>sp|Q9NWF9|UB7I1_HUMAN E3 ubiquitin ligase TRIAD3 (Ubiquitin conjugating enzyme 7
interacting protein 1) (Zinc finger protein inhibiting
NF-kappa-B)
Length = 866
Score = 50.8 bits (120), Expect = 4e-06
Identities = 34/117 (29%), Positives = 45/117 (38%), Gaps = 6/117 (5%)
Frame = +3
Query: 333 CPRCEMSVVTDEDEFGI-CPXXXXXXXXXXNMT----YHGPGKCEG-NEKRKEKERLNQI 494
CP C + D D CP H CE EK K R +
Sbjct: 605 CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIE 664
Query: 495 EEMLNEKHKRCPSCNQAYEKNGGCNKMICNCGVYFCFLCSKILDKFNPYNHFGLRPK 665
E+M + ++C C K+ GCN+M C CG C+LC N Y+HF P+
Sbjct: 665 EKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRV---SINGYDHFCQHPR 718
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,203,143
Number of Sequences: 369166
Number of extensions: 1490921
Number of successful extensions: 4790
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4542
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4759
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)