Planaria EST Database


DrC_02945

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02945
         (893 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O60341|LSD1_HUMAN  Lysine-specific histone demethylase 1 ...   118   3e-26
sp|Q6ZQ88|LSD1_MOUSE  Lysine-specific histone demethylase 1 ...   118   3e-26
sp|Q9NWM0|SMOX_HUMAN  Spermine oxidase (Polyamine oxidase 1)...    73   9e-13
sp|Q99K82|SMOX_MOUSE  Spermine oxidase (Polyamine oxidase 1)...    72   3e-12
sp|Q6QHF9|PAOX_HUMAN  Peroxisomal N1-acetyl-spermine/spermid...    72   3e-12
sp|Q9XWP6|SPR5_CAEEL  Suppressor of presenilin 5 (P110b homo...    71   4e-12
sp|Q8C0L6|PAOX_MOUSE  Peroxisomal N1-acetyl-spermine/spermid...    70   1e-11
sp||Q865R1_3  [Segment 3 of 3] Peroxisomal N1-acetyl-spermin...    70   1e-11
sp|Q21988|AMX1_CAEEL  Amine oxidase family member 1                67   7e-11
sp|O64411|PAO_MAIZE  Polyamine oxidase precursor                   63   1e-09
>sp|O60341|LSD1_HUMAN Lysine-specific histone demethylase 1 (Amine oxidase flavin
            containing domain protein 2) (AOF2 protein) (BRAF35-HDAC
            complex protein BHC110)
          Length = 852

 Score =  118 bits (295), Expect = 3e-26
 Identities = 84/259 (32%), Positives = 117/259 (45%)
 Frame = +3

Query: 6    FKSDVVVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKER 185
            +K D V+CTLPLGVLK+         + QF PPLPEWK  ++  +GFG  +KVV+CF   
Sbjct: 616  YKCDAVLCTLPLGVLKQQ------PPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRV 669

Query: 186  FWGSNNMKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXXXX 365
            FW   ++ +F  + S    RGE   F+   +                             
Sbjct: 670  FW-DPSVNLFGHVGSTTASRGELFLFWNLYK------------------------APILL 704

Query: 366  XXXCGEAATAYALEKDLTDAEMGKRALQSLRDIFLKRKITVPEPSLIHVYRWTKDLHARG 545
                GEAA    + ++++D  +  R L  L+ IF      VP+P    V RW  D  ARG
Sbjct: 705  ALVAGEAA---GIMENISDDVIVGRCLAILKGIF--GSSAVPQPKETVVSRWRADPWARG 759

Query: 546  VFSYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTHSAGIGT 725
             +SY+  G+S  D +  A P+          Q          +PRLFFAGEHT      T
Sbjct: 760  SYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQ---------PIPRLFFAGEHTIRNYPAT 810

Query: 726  IQGAMMSGLRAASDICKYY 782
            + GA++SGLR A  I   +
Sbjct: 811  VHGALLSGLREAGRIADQF 829
>sp|Q6ZQ88|LSD1_MOUSE Lysine-specific histone demethylase 1 (Amine oxidase flavin
            containing domain protein 2) (AOF2 protein) (BRAF35-HDAC
            complex protein BHC110)
          Length = 853

 Score =  118 bits (295), Expect = 3e-26
 Identities = 84/259 (32%), Positives = 117/259 (45%)
 Frame = +3

Query: 6    FKSDVVVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKER 185
            +K D V+CTLPLGVLK+         + QF PPLPEWK  ++  +GFG  +KVV+CF   
Sbjct: 617  YKCDAVLCTLPLGVLKQQ------PPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRV 670

Query: 186  FWGSNNMKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXXXX 365
            FW   ++ +F  + S    RGE   F+   +                             
Sbjct: 671  FW-DPSVNLFGHVGSTTASRGELFLFWNLYK------------------------APILL 705

Query: 366  XXXCGEAATAYALEKDLTDAEMGKRALQSLRDIFLKRKITVPEPSLIHVYRWTKDLHARG 545
                GEAA    + ++++D  +  R L  L+ IF      VP+P    V RW  D  ARG
Sbjct: 706  ALVAGEAA---GIMENISDDVIVGRCLAILKGIF--GSSAVPQPKETVVSRWRADPWARG 760

Query: 546  VFSYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTHSAGIGT 725
             +SY+  G+S  D +  A P+          Q          +PRLFFAGEHT      T
Sbjct: 761  SYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQ---------PIPRLFFAGEHTIRNYPAT 811

Query: 726  IQGAMMSGLRAASDICKYY 782
            + GA++SGLR A  I   +
Sbjct: 812  VHGALLSGLREAGRIADQF 830
>sp|Q9NWM0|SMOX_HUMAN Spermine oxidase (Polyamine oxidase 1) (PAO-1) (PAOh1)
          Length = 555

 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 69/257 (26%), Positives = 101/257 (39%)
 Frame = +3

Query: 12  SDVVVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKERFW 191
           +D V+ T+ LGVLK    +        F P LP  KV +I+ LG G  DK+ + F+E FW
Sbjct: 325 ADHVIVTVSLGVLKRQYTS-------FFRPGLPTEKVAAIHRLGIGTTDKIFLEFEEPFW 377

Query: 192 GSNNMKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXXXXXX 371
           G     +    + + E          + RK                    ++        
Sbjct: 378 GPECNSLQFVWEDEAESHTLTYPPELWYRKICG----------FDVLYPPERYGHVLSGW 427

Query: 372 XCGEAATAYALEKDLTDAEMGKRALQSLRDIFLKRKITVPEPSLIHVYRWTKDLHARGVF 551
            CGE A       D   AE+    L+            +P+P  I    W  + + RG +
Sbjct: 428 ICGEEALVMEKCDDEAVAEICTEMLRQFTG-----NPNIPKPRRILRSAWGSNPYFRGSY 482

Query: 552 SYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTHSAGIGTIQ 731
           SY   G+S  DVE  A PLP  E            P+Q++     F+GE TH     T  
Sbjct: 483 SYTQVGSSGADVEKLAKPLPYTESSKT-------APMQVL-----FSGEATHRKYYSTTH 530

Query: 732 GAMMSGLRAASDICKYY 782
           GA++SG R A+ + + Y
Sbjct: 531 GALLSGQREAARLIEMY 547
>sp|Q99K82|SMOX_MOUSE Spermine oxidase (Polyamine oxidase 1) (PAO-1) (PAOh1)
          Length = 555

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 69/257 (26%), Positives = 101/257 (39%)
 Frame = +3

Query: 12  SDVVVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKERFW 191
           +D V+ T+ LGVLK    +        F P LP  KV +I+ LG G  DK+ + F+E FW
Sbjct: 325 ADHVIVTVSLGVLKRQYTS-------FFRPCLPTEKVAAIHRLGIGTTDKIFLEFEEPFW 377

Query: 192 GSNNMKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXXXXXX 371
           G     +    + + E          + RK                    ++        
Sbjct: 378 GPECNSLQFVWEDEAESCTLTYPPELWYRKICG----------FDVLYPPERYGHVLSGW 427

Query: 372 XCGEAATAYALEKDLTDAEMGKRALQSLRDIFLKRKITVPEPSLIHVYRWTKDLHARGVF 551
            CGE A       D   AE+    L+            +P+P  I    W  + + RG +
Sbjct: 428 ICGEEALVMERCDDEAVAEICTEMLRQFTG-----NPNIPKPRRILRSAWGSNPYFRGSY 482

Query: 552 SYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTHSAGIGTIQ 731
           SY   G+S  DVE  A PLP  E            P+Q++     F+GE TH     T  
Sbjct: 483 SYTQVGSSGADVEKLAKPLPYTESSKT-------APMQVL-----FSGEATHRKYYSTTH 530

Query: 732 GAMMSGLRAASDICKYY 782
           GA++SG R A+ + + Y
Sbjct: 531 GALLSGQREAARLIEMY 547
>sp|Q6QHF9|PAOX_HUMAN Peroxisomal N1-acetyl-spermine/spermidine oxidase (Polyamine oxidase)
          Length = 649

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 70/276 (25%), Positives = 112/276 (40%), Gaps = 6/276 (2%)
 Frame = +3

Query: 6    FKSDVVVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKER 185
            F +  V+ T+PLG L+E ++         F PPLP  K ++I  +GFG  +K+ + F+E 
Sbjct: 416  FPAHHVIVTVPLGFLREHLDT-------FFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEP 468

Query: 186  FWGSNN--MKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXX 359
            FW  +   +++  +  S  E     +Q   F +                           
Sbjct: 469  FWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRK----------------LIGFVVLPAFA 512

Query: 360  XXXXXCGEAATAYALEKDLTDAEMGKRALQSLRDIFLKRKIT----VPEPSLIHVYRWTK 527
                 CG  A    LE +  +    +  L  L  +   R++T    +P P  +   RW  
Sbjct: 513  SVHVLCGFIA---GLESEFMETLSDEEVLLCLTQVL--RRVTGNPRLPAPKSVLRSRWHS 567

Query: 528  DLHARGVFSYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTH 707
              + RG +SY+  G++  D++  A PLP             G   QL   ++ FAGE TH
Sbjct: 568  APYTRGSYSYVAVGSTGGDLDLLAQPLPAD-----------GAGAQL---QILFAGEATH 613

Query: 708  SAGIGTIQGAMMSGLRAASDICKYYFPQLPNILSRL 815
                 T  GA++SG R A  +   + PQ+     RL
Sbjct: 614  RTFYSTTHGALLSGWREADRLLSLWAPQVQQPRPRL 649
>sp|Q9XWP6|SPR5_CAEEL Suppressor of presenilin 5 (P110b homolog)
          Length = 770

 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 70/255 (27%), Positives = 107/255 (41%), Gaps = 1/255 (0%)
 Frame = +3

Query: 9    KSDVVVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKERF 188
            K+  VV TLP+GVLK++I       +P F+P LP+ KV++I  +G G  +K ++ F   F
Sbjct: 471  KAAFVVSTLPIGVLKKTII--ADERAPTFTPSLPDKKVEAIRNIGCGSVNKCILEFDRVF 528

Query: 189  WGSN-NMKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXXXX 365
            W +N     F  +    + RG       +S    S+                        
Sbjct: 529  WTANGGRNQFVTVSPNIKTRG---SMNIWSSVPGSK---------------------VLC 564

Query: 366  XXXCGEAATAYALEKDLTDAEMGKRALQSLRDIFLKRKITVPEPSLIHVYRWTKDLHARG 545
                GE A       +L D  + + A+ +L+  F       P  +  H+ RW  D  A G
Sbjct: 565  TYIVGEEAML-----ELPDDVIIQNAMINLQKAFGNNCPRAPISA--HITRWHDDELAFG 617

Query: 546  VFSYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTHSAGIGT 725
              +++      T  ++   PL   +                 + R++FAGEHT S+   T
Sbjct: 618  SGAFMSLRTETTSFDDVMEPLKTSDG----------------MSRVYFAGEHTCSSYTST 661

Query: 726  IQGAMMSGLRAASDI 770
            IQGA MSG RAA+DI
Sbjct: 662  IQGAWMSGARAAADI 676
>sp|Q8C0L6|PAOX_MOUSE Peroxisomal N1-acetyl-spermine/spermidine oxidase (Polyamine
           oxidase)
          Length = 504

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 71/269 (26%), Positives = 105/269 (39%), Gaps = 4/269 (1%)
 Frame = +3

Query: 21  VVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKERFWGSN 200
           V+ T+PLG LKE            F PPLP  K ++I  LGFG  +K+ + F+E FW  +
Sbjct: 276 VIVTVPLGFLKEH-------QDTFFEPPLPAKKAEAIKKLGFGTNNKIFLEFEEPFWEPD 328

Query: 201 NMKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXXXXXXXCG 380
              +    +         +Q  A S +D                    Q         CG
Sbjct: 329 CQFIQVVWEDTSP-----LQDTALSLQDT---------WFKKLIGFLVQPSFESSHVLCG 374

Query: 381 EAATAYALEKDLTDAEMGKRALQSLRDIFLKRKIT----VPEPSLIHVYRWTKDLHARGV 548
             A    LE +  +    +  L SL  +   R++T    +P    +   +W    + RG 
Sbjct: 375 FIA---GLESEFMETLSDEEVLLSLTQVL--RRVTGNPQLPAAKSVRRSQWHSAPYTRGS 429

Query: 549 FSYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTHSAGIGTI 728
           +SY+  G++  D++  A PLP             G   QL V    FAGE TH     T 
Sbjct: 430 YSYVAVGSTGDDLDLMAQPLP-----------EDGTGTQLQV---LFAGEATHRTFYSTT 475

Query: 729 QGAMMSGLRAASDICKYYFPQLPNILSRL 815
            GA++SG R A  +   +  Q+     RL
Sbjct: 476 HGALLSGWREADRLVSLWDSQVEQSRPRL 504
>sp||Q865R1_3 [Segment 3 of 3] Peroxisomal N1-acetyl-spermine/spermidine oxidase
           (Polyamine oxidase)
          Length = 452

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 70/268 (26%), Positives = 110/268 (41%), Gaps = 6/268 (2%)
 Frame = +3

Query: 6   FKSDVVVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKER 185
           F +  VV T+PLG  K+ ++         F PPLP  KV++I  +GFG  +K+ + F+E 
Sbjct: 219 FPAHHVVVTVPLGFFKKHLDT-------FFEPPLPTEKVEAIRKIGFGTNNKIFLEFEEP 271

Query: 186 FWGSN--NMKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXX 359
           FW  +  +++V  +  S  E     +Q   F +                           
Sbjct: 272 FWEPDCQHIQVVWEDMSPLEDTAPELQDAWFKK----------------LIGFWVLPPFQ 315

Query: 360 XXXXXCGEAATAYALEKDLTDAEMGKRALQSLRDIFLKRKIT----VPEPSLIHVYRWTK 527
                CG  A    LE +  +    +  L+SL  +   R++T    +P P  +    W  
Sbjct: 316 ASHVLCGFIA---GLESEFMETLSDEDVLRSLTQVL--RRVTGNPQLPAPRSMLRSCWHS 370

Query: 528 DLHARGVFSYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTH 707
             + RG +SY+  G+S  D++  A PLP             G   QL   ++ FAGE TH
Sbjct: 371 APYTRGSYSYVAVGSSGDDMDRLAQPLP-----------SDGKGAQL---QVLFAGEATH 416

Query: 708 SAGIGTIQGAMMSGLRAASDICKYYFPQ 791
                   GA++SG R A  +   + PQ
Sbjct: 417 RTFYSPTHGALLSGWREADRLMTLWDPQ 444
>sp|Q21988|AMX1_CAEEL Amine oxidase family member 1
          Length = 783

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 67/257 (26%), Positives = 102/257 (39%), Gaps = 5/257 (1%)
 Frame = +3

Query: 15   DVVVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKERFWG 194
            D VV T  L VLK +       +S  F PPLP  K K+I+ LG G+ +K+ + F  RFW 
Sbjct: 565  DKVVITTSLSVLKSN-------HSKMFVPPLPIEKQKAIDDLGAGLIEKIAVKFDRRFWD 617

Query: 195  SNN-----MKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXX 359
            + +      + F ++   +  R  F  FY FS KD +                       
Sbjct: 618  TVDADGLRTEYFGKVSDCKTDRSLFNIFYDFSGKDPNGEDTFVLMSYV------------ 665

Query: 360  XXXXXCGEAATAYALEKDLTDAEMGKRALQSLRDIFLKRKITVPEPSLIHVYRWTKDLHA 539
                     A    L   LT++E+  +   +LR +F    I      + H   W  D   
Sbjct: 666  --------TAEHVNLVNVLTESEVADKFCATLRKMFPSAVINPLGHMMSH---WGADRFV 714

Query: 540  RGVFSYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTHSAGI 719
               ++++P G+               + D    Q +       +  +L+FAGEHT +A  
Sbjct: 715  GMSYTFVPFGS---------------DGDATYNQLKKS-----IDEKLYFAGEHTIAAEP 754

Query: 720  GTIQGAMMSGLRAASDI 770
             T+ GA +SGLR A  I
Sbjct: 755  QTMAGAYISGLREAGQI 771
>sp|O64411|PAO_MAIZE Polyamine oxidase precursor
          Length = 500

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 61/267 (22%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
 Frame = +3

Query: 6   FKSDVVVCTLPLGVLKESINNPVGTNSPQFSPPLPEWKVKSINALGFGMFDKVVMCFKER 185
           + +D V+ +  LGVL+  +         QF P LP WKV++I      ++ K+ + F  +
Sbjct: 285 YSADYVMVSASLGVLQSDLI--------QFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRK 336

Query: 186 FWGSNNMKVFAQLKSKREQRGEFMQFYAFSRKDASRXXXXXXXXXXXXXXXXKQXXXXXX 365
           FW     + F    S R  RG +  +  F ++                    +Q      
Sbjct: 337 FWPEGKGREFFLYASSR--RGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQ------ 388

Query: 366 XXXCGEAATAYALEKDLTDAEMGKRALQSLRDIFLKRKITVPEPSLIHVYRWTKDLHARG 545
                            +D +     +Q LR +F  +   VP+ + I V RW  D   +G
Sbjct: 389 -----------------SDEQTKAEIMQVLRKMFPGK--DVPDATDILVPRWWSDRFYKG 429

Query: 546 VFSYIPEGASLTDVENAAAPLPVQEQDTNQRQRRSGGPVQLVVPRLFFAGEHTHSAGIGT 725
            FS  P G +  + +   AP                      V R++F GEHT     G 
Sbjct: 430 TFSNWPVGVNRYEYDQLRAP----------------------VGRVYFTGEHTSEHYNGY 467

Query: 726 IQGAMMSGLRAA--------SDICKYY 782
           + GA +SG+ +A          +CKY+
Sbjct: 468 VHGAYLSGIDSAEILINCAQKKMCKYH 494
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,486,547
Number of Sequences: 369166
Number of extensions: 2117593
Number of successful extensions: 5277
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5015
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5257
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)