Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02942 (418 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q5ZIJ9|MIB2_CHICK Ubiquitin ligase protein MIB2 (Mind bo... 38 0.007 sp|Q02989|LITA_LATMA Alpha-latroinsectotoxin precursor (Alp... 37 0.021 sp|Q04861|NFKB1_CHICK Nuclear factor NF-kappa-B p105 subuni... 36 0.028 sp|P19838|NFKB1_HUMAN Nuclear factor NF-kappa-B p105 subuni... 35 0.080 sp|P25799|NFKB1_MOUSE Nuclear factor NF-kappa-B p105 subuni... 34 0.14 sp|Q63369|NFKB1_RAT Nuclear factor NF-kappa-B p105 subunit ... 34 0.14 sp|Q9VUX2|MIB_DROME Ubiquitin ligase protein mind-bomb (Min... 33 0.18 sp|Q68LP1|MIB2_RAT Ubiquitin ligase protein MIB2 (Mind bomb... 33 0.18 sp|Q05823|RN5A_HUMAN 2-5A-dependent ribonuclease (2-5A-depe... 33 0.23 sp|Q8R516|MIB2_MOUSE Ubiquitin ligase protein MIB2 (Mind bo... 33 0.23
>sp|Q5ZIJ9|MIB2_CHICK Ubiquitin ligase protein MIB2 (Mind bomb homolog 2) Length = 954 Score = 38.1 bits (87), Expect = 0.007 Identities = 16/45 (35%), Positives = 29/45 (64%) Frame = +3 Query: 180 INMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 +N++N ++PL+LA+I ++ L+ + V E D N D +GDT + Sbjct: 659 VNVKNNRNQTPLHLAIIQGHVGLVQLLVSEGSDVNAEDEDGDTAM 703
>sp|Q02989|LITA_LATMA Alpha-latroinsectotoxin precursor (Alpha-LIT) Length = 1411 Score = 36.6 bits (83), Expect = 0.021 Identities = 18/47 (38%), Positives = 28/47 (59%) Frame = +3 Query: 174 SYINMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 S +N++NI E P YLA+ + + D FV + + N D NG+T+L Sbjct: 861 SLMNVKNIRNEYPFYLAVEKRYKDIFDYFVSKDANVNEVDHNGNTLL 907
Score = 28.1 bits (61), Expect = 7.5 Identities = 12/38 (31%), Positives = 25/38 (65%), Gaps = 1/38 (2%) Frame = +3 Query: 174 SYINMRNISGESPLYLALITKNLSLIDVFV-IEYVDFN 284 +Y+N + +G +PL+ A +T NL ++D + +Y++ N Sbjct: 659 AYLNDGDANGMTPLHYAAMTGNLEMVDFLLNQQYININ 696
Score = 27.7 bits (60), Expect = 9.8 Identities = 16/45 (35%), Positives = 25/45 (55%) Frame = +3 Query: 180 INMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 IN+++ G +PL+LA + NLS+ + + N D NG T L Sbjct: 628 INIKSKVGLTPLHLATLQNNLSVSKLLAGKGAYLNDGDANGMTPL 672
>sp|Q04861|NFKB1_CHICK Nuclear factor NF-kappa-B p105 subunit [Contains: Nuclear factor NF-kappa-B p50 subunit] Length = 984 Score = 36.2 bits (82), Expect = 0.028 Identities = 18/45 (40%), Positives = 30/45 (66%) Frame = +3 Query: 180 INMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 INMRN ++PL+LA+ITK +++ + + NL D +G++VL Sbjct: 573 INMRNDLYQTPLHLAVITKQAEVVEDLLKAGANVNLLDRHGNSVL 617
>sp|P19838|NFKB1_HUMAN Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) [Contains: Nuclear factor NF-kappa-B p50 subunit] Length = 968 Score = 34.7 bits (78), Expect = 0.080 Identities = 18/48 (37%), Positives = 30/48 (62%) Frame = +3 Query: 171 ESYINMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 + INMRN ++PL+LA+ITK +++ + D +L D G++VL Sbjct: 572 DDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVL 619
>sp|P25799|NFKB1_MOUSE Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF-kappa-B p50 subunit] Length = 971 Score = 33.9 bits (76), Expect = 0.14 Identities = 18/48 (37%), Positives = 30/48 (62%) Frame = +3 Query: 171 ESYINMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 + INMRN ++PL+LA+ITK +++ + D +L D G++VL Sbjct: 568 DDIINMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVL 615
>sp|Q63369|NFKB1_RAT Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) [Contains: Nuclear factor NF-kappa-B p50 subunit] Length = 522 Score = 33.9 bits (76), Expect = 0.14 Identities = 18/48 (37%), Positives = 30/48 (62%) Frame = +3 Query: 171 ESYINMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 + INMRN ++PL+LA+ITK +++ + D +L D G++VL Sbjct: 119 DDIINMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVL 166
>sp|Q9VUX2|MIB_DROME Ubiquitin ligase protein mind-bomb (Mind bomb homolog) (D-mib) Length = 1226 Score = 33.5 bits (75), Expect = 0.18 Identities = 13/45 (28%), Positives = 31/45 (68%) Frame = +3 Query: 180 INMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 ++ +N++ ++ L+LA+ +++ ++ + V + D N+PD +GDT L Sbjct: 763 MDRQNVNLQTALHLAVERQHVQIVKLLVQDGADLNIPDKDGDTPL 807
>sp|Q68LP1|MIB2_RAT Ubiquitin ligase protein MIB2 (Mind bomb homolog 2) (RBSC-skeletrophin/dystrophin-like polypeptide) Length = 971 Score = 33.5 bits (75), Expect = 0.18 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = +3 Query: 180 INMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 +N+RN +SPL+LA+ +L L+ + V + N D GDT L Sbjct: 675 VNVRNRKLQSPLHLAVQQAHLGLVPLLVDAGCNVNTEDEEGDTAL 719
>sp|Q05823|RN5A_HUMAN 2-5A-dependent ribonuclease (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4) Length = 741 Score = 33.1 bits (74), Expect = 0.23 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = +3 Query: 180 INMRNISGESPLYLALITKNLSLID-VFVIEYVDFNLPDTNGDTVLCTLFKTFTNATDIP 356 +N+R G++PL LA+ K+L L+ + E+++ N D++G T L + Sbjct: 232 VNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVEL-------- 283 Query: 357 YLEKTAKIMINGGAS 401 L+K A+++ GAS Sbjct: 284 KLKKIAELLCKRGAS 298
>sp|Q8R516|MIB2_MOUSE Ubiquitin ligase protein MIB2 (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike) Length = 973 Score = 33.1 bits (74), Expect = 0.23 Identities = 17/45 (37%), Positives = 25/45 (55%) Frame = +3 Query: 180 INMRNISGESPLYLALITKNLSLIDVFVIEYVDFNLPDTNGDTVL 314 +N+RN +SPL+LA+ +L L+ + V N D GDT L Sbjct: 677 VNVRNRKLQSPLHLAVQQAHLGLVPLLVDAGCSVNTEDEEGDTAL 721
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 42,055,596 Number of Sequences: 369166 Number of extensions: 722434 Number of successful extensions: 1792 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1736 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1792 length of database: 68,354,980 effective HSP length: 99 effective length of database: 50,066,215 effective search space used: 1952582385 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)