Planaria EST Database


DrC_02909

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02909
         (870 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O77469|FBLN1_CAEEL  Fibulin-1 precursor                         89   2e-17
sp|P35556|FBN2_HUMAN  Fibrillin-2 precursor                        89   2e-17
sp|Q61555|FBN2_MOUSE  Fibrillin-2 precursor                        89   2e-17
sp|O88281|EGFL3_RAT  Multiple EGF-like-domain protein 3 prec...    88   3e-17
sp|P35555|FBN1_HUMAN  Fibrillin-1 precursor                        87   6e-17
sp|P98133|FBN1_BOVIN  Fibrillin-1 precursor (MP340)                87   6e-17
sp|Q08761|PROS_MOUSE  Vitamin K-dependent protein S precursor      86   1e-16
sp|Q9TV36|FBN1_PIG  Fibrillin-1 precursor                          86   2e-16
sp|Q61554|FBN1_MOUSE  Fibrillin-1 precursor                        85   2e-16
sp|P53813|PROS_RAT  Vitamin K-dependent protein S precursor        84   4e-16
>sp|O77469|FBLN1_CAEEL Fibulin-1 precursor
          Length = 728

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 53/156 (33%), Positives = 76/156 (48%), Gaps = 13/156 (8%)
 Frame = +2

Query: 17  ICKIGFIWSGD-RGCIDIDECATDVKPGS--CQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
           IC  GF    D   C DIDEC+     G+  C   C+NT GS+ C CPPG+ + P    C
Sbjct: 499 ICDRGFALGPDGTKCEDIDECSIWAGSGNDLCMGGCINTKGSYLCQCPPGYKIQPDGRTC 558

Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLK-------ACLSNCTDK 346
           +DVDEC +  +   + K C+NT G++ C    CP  Y  D   K       +C+  C+ +
Sbjct: 559 VDVDECAM-GECAGSDKVCVNTLGSFKCHSIDCPTNYIHDSLNKNQIADGYSCIKVCSTE 617

Query: 347 SPKCLTQASR---IQYVVVQMTGSMAQPVEVRVINT 445
             +CL   +R    Q+  V    ++  P+EV  I T
Sbjct: 618 DTECLGNHTREVLYQFRAVPSLKTIISPIEVSRIVT 653

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 44/108 (40%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
 Frame = +2

Query: 20  CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
           CK GF  + D R C D++EC T +   +C+ +CVN  GS+ C+C  GF L P   KC D+
Sbjct: 459 CKPGFQLASDGRRCEDVNECTTGI--AACEQKCVNIPGSYQCICDRGFALGPDGTKCEDI 516

Query: 197 DECRI----NSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
           DEC I     +D+C     CINT G+Y C   +CP GY      + C+
Sbjct: 517 DECSIWAGSGNDLCMGG--CINTKGSYLC---QCPPGYKIQPDGRTCV 559

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 3/137 (2%)
 Frame = +2

Query: 8   KHEICKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTM 181
           K  +C  G+  +G  G C D++EC    + G C   +C+N  G++ C C PG+       
Sbjct: 371 KGNLCAHGYEVNGATGFCEDVNEC----QQGVCGSMECINLPGTYKCKCGPGYEFNDAKK 426

Query: 182 KCIDVDEC-RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
           +C DVDEC +    +C     CINT G++ C   KC  G    F+L +    C D + +C
Sbjct: 427 RCEDVDECIKFAGHVCDLSAECINTIGSFEC---KCKPG----FQLASDGRRCEDVN-EC 478

Query: 359 LTQASRIQYVVVQMTGS 409
            T  +  +   V + GS
Sbjct: 479 TTGIAACEQKCVNIPGS 495

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +2

Query: 56  CIDIDECATDV-KPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPN 232
           C D+DEC            +C+NT GSF C C PGF L     +C DV+EC      C  
Sbjct: 428 CEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGFQLASDGRRCEDVNECTTGIAACEQ 487

Query: 233 RKFCINTPGNYSCIEPKCPDGY 298
           +  C+N PG+Y CI   C  G+
Sbjct: 488 K--CVNIPGSYQCI---CDRGF 504

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 36/116 (31%), Positives = 51/116 (43%), Gaps = 23/116 (19%)
 Frame = +2

Query: 20  CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHC------------------- 142
           C +G+++     C+D+DEC          YQC NT GS+ C                   
Sbjct: 268 CPMGWLFQHGH-CVDVDECNLGSHDCGPLYQCRNTQGSYRCDAKKCGDGELQNPMTGECT 326

Query: 143 --LCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEP--KCPDGY 298
              CP G+  YPK   C D+DEC +    C   + C+NTPG++ C +    C  GY
Sbjct: 327 SITCPNGY--YPKNGMCNDIDEC-VTGHNCGAGEECVNTPGSFRCQQKGNLCAHGY 379

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 37/138 (26%), Positives = 48/138 (34%), Gaps = 46/138 (33%)
 Frame = +2

Query: 20  CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCL----------------- 145
           C+ GF  + D   C+D +EC T   P +    CVNT G + C                  
Sbjct: 180 CRSGFDLAPDGMACVDRNECLTRQSPCTQSEDCVNTIGGYICQRRISRLVPHRHRANRIG 239

Query: 146 ----------------------------CPPGFTLYPKTMKCIDVDECRINSDICPNRKF 241
                                       CP G+    +   C+DVDEC + S  C     
Sbjct: 240 NAPRRMRDDPYSRAGEYREASQANTEFGCPMGWLF--QHGHCVDVDECNLGSHDCGPLYQ 297

Query: 242 CINTPGNYSCIEPKCPDG 295
           C NT G+Y C   KC DG
Sbjct: 298 CRNTQGSYRCDAKKCGDG 315

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
 Frame = +2

Query: 68  DECATDVKPGSCQYQCVNTYGS-FHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFC 244
           D CA+      C++ C +  G    C C  GF L P  M C+D +EC      C   + C
Sbjct: 157 DRCASS----HCEHLCHDRGGEKVECSCRSGFDLAPDGMACVDRNECLTRQSPCTQSEDC 212

Query: 245 INTPGNYSC 271
           +NT G Y C
Sbjct: 213 VNTIGGYIC 221
>sp|P35556|FBN2_HUMAN Fibrillin-2 precursor
          Length = 2911

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 46/117 (39%), Positives = 60/117 (51%), Gaps = 3/117 (2%)
 Frame = +2

Query: 20   CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  G+  + DR GC DIDEC   +  G C  QC N+ GS+ C C  G+ L P    C D+
Sbjct: 1226 CNPGYQATPDRQGCTDIDECM--IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI 1283

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL--SNCTDKSPKCL 361
            DEC  N DIC   + C N PG Y C+   C DG+     +K C+  + C   S  C+
Sbjct: 1284 DECENNPDICDGGQ-CTNIPGEYRCL---CYDGFMASMDMKTCIDVNECDLNSNICM 1336

 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 42/106 (39%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
 Frame = +2

Query: 20   CKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            CK+G+        CID+DEC+   KP  C Y C NT GS+ C CP G+ L      C D+
Sbjct: 2475 CKVGYTTDISGTSCIDLDECSQSPKP--CNYICKNTEGSYQCSCPRGYVLQEDGKTCKDL 2532

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
            DEC+     C  +  C+NT G ++C   KCP G  F     AC+ N
Sbjct: 2533 DECQTKQHNC--QFLCVNTLGGFTC---KCPPG--FTQHHTACIDN 2571

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 41/95 (43%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DI+EC     PG C Y +C NT GSF C C  GF L  +   C D+DECRI+ D+C    
Sbjct: 1072 DINECKAF--PGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLC-GSG 1128

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
             C+NTPG++ C   +C +GY   F +   + NC D
Sbjct: 1129 ICVNTPGSFEC---ECFEGYESGFMM---MKNCMD 1157

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 44/95 (46%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
 Frame = +2

Query: 20  CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
           C+ GFI +   G C D+DEC     PG CQ   C+NT GSF C CP G      T KC D
Sbjct: 260 CRRGFIPNIRTGACQDVDEC--QAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCED 317

Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
           +DEC I   IC   + C NT G+Y C+   CP GY
Sbjct: 318 IDECSIIPGICETGE-CSNTVGSYFCV---CPRGY 348

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 43/130 (33%), Positives = 62/130 (47%)
 Frame = +2

Query: 20  CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
           C +G+    +  CID+DEC ++         CVNT GS++C C  GF   P    CID+D
Sbjct: 520 CNMGYKQDANGDCIDVDECTSNPCTNG---DCVNTPGSYYCKCHAGFQRTPTKQACIDID 576

Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASRI 379
           EC  N  +C N + C+N+ G++ CI        N  F L     NC D   +C T    +
Sbjct: 577 ECIQNGVLCKNGR-CVNSDGSFQCI-------CNAGFELTTDGKNCVDHD-ECTTTNMCL 627

Query: 380 QYVVVQMTGS 409
             + +   GS
Sbjct: 628 NGMCINEDGS 637

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 40/93 (43%), Positives = 53/93 (56%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C+ G+I +G + CID+DEC+      S   QCVNT GS+ C C  GFT       C DVD
Sbjct: 1394 CREGWIGNGIK-CIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVD 1450

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
            EC  N ++C N + C+N PG Y C   +C  G+
Sbjct: 1451 ECAENINLCENGQ-CLNVPGAYRC---ECEMGF 1479

 Score = 73.9 bits (180), Expect = 5e-13
 Identities = 52/163 (31%), Positives = 73/163 (44%), Gaps = 5/163 (3%)
 Frame = +2

Query: 50   RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
            + C+DID C  +  P  C+   CVNT GSF C CP G  L P    C+D++EC ++ ++C
Sbjct: 1153 KNCMDIDGCERN--PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLC 1210

Query: 227  PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ--YVVV 394
             N K C+N  G Y C    C  GY      + C  +  C   +  C TQ +  +  Y   
Sbjct: 1211 RNGK-CVNMIGTYQC---SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECS 1266

Query: 395  QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
               G    P + R    + + ENN    +     NIP  Y  L
Sbjct: 1267 CSEGYALMP-DGRSCADIDECENNPDICDGGQCTNIPGEYRCL 1308

 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 41/120 (34%), Positives = 63/120 (52%), Gaps = 2/120 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            +C  GF+ S D + CID++EC  D+    C + +C NT GSF C C  G+++   T  C 
Sbjct: 1308 LCYDGFMASMDMKTCIDVNEC--DLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCT 1365

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
            DVDEC I +  C     C+N PG++ C    C +G+  +      L  C++ + +C   A
Sbjct: 1366 DVDECEIGAHNCDMHASCLNIPGSFKC---SCREGWIGNGIKCIDLDECSNGTHQCSINA 1422

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 42/106 (39%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
 Frame = +2

Query: 17  ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           IC  GF  + D + C+D DEC T      C    C+N  GSF C+C PGF L P    C 
Sbjct: 600 ICNAGFELTTDGKNCVDHDECTTT---NMCLNGMCINEDGSFKCICKPGFVLAPNGRYCT 656

Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
           DVDEC+    IC N   CIN+ G++ C    CP G       + C+
Sbjct: 657 DVDECQ-TPGICMN-GHCINSEGSFRC---DCPPGLAVGMDGRVCV 697

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 42/106 (39%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DI+ECA D  P  C    C N  GS+ C C  G+        CID+DEC +N  +C N  
Sbjct: 767  DINECALD--PDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDN-G 823

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
             C NTPG+YSC    CP GY F    + C      +S  C+  A R
Sbjct: 824  LCRNTPGSYSC---TCPPGYVFRTETETCEDINECESNPCVNGACR 866

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 38/80 (47%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DIDEC     PG CQ   C+NT+GSF C CP G+ L   T  C D+DEC  +  +C    
Sbjct: 1649 DIDECQE--LPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVC-GPG 1705

Query: 239  FCINTPGNYSCIEPKCPDGY 298
             C NT GNY+CI   CP  Y
Sbjct: 1706 TCYNTLGNYTCI---CPPEY 1722

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 38/107 (35%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRG-CIDIDECATDVKPGSCQ-YQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C IG+    D+  C D+DECA  +     +   C N  G+F C+CPPG    P    C+D
Sbjct: 2278 CPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVD 2337

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
             +ECR    IC N + C+N  G+Y C   +C +G+        CL N
Sbjct: 2338 ENECRTKPGICENGR-CVNIIGSYRC---ECNEGFQSSSSGTECLDN 2380

 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 42/102 (41%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DIDEC   V P  C   QC+NT GSF C C  G+T       CID+DEC  +   C    
Sbjct: 2448 DIDECK--VMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC--NY 2503

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
             C NT G+Y C    CP GY      K C  L  C  K   C
Sbjct: 2504 ICKNTEGSYQC---SCPRGYVLQEDGKTCKDLDECQTKQHNC 2542

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 59   IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            +DIDEC     PG C    C+N  GSF C CP GF+     + C D+DEC    ++C   
Sbjct: 1806 VDIDECKEI--PGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 1863

Query: 236  KFCINTPGNYSCIEPKCPDGY 298
              CIN+PG+Y C   +C  G+
Sbjct: 1864 ADCINSPGSYRC---ECAAGF 1881

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 3/116 (2%)
 Frame = +2

Query: 20   CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C+ GF + +    C D+DEC  + +   CQ+ C N  G + C CP G+  + +  +C+D 
Sbjct: 2598 CQRGFSLDATGLNCEDVDECDGNHR---CQHGCQNILGGYRCGCPQGYIQHYQWNQCVDE 2654

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
            +EC  N + C +   C NT G+Y C    CP G++FD    AC  ++ C+     C
Sbjct: 2655 NECS-NPNACGSAS-CYNTLGSYKCA---CPSGFSFDQFSSACHDVNECSSSKNPC 2705

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 38/115 (33%), Positives = 53/115 (46%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            +C  GF  + +  C+DIDEC++         +C N  GSF CLC  G+ L P    CID 
Sbjct: 1957 LCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDT 2016

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCL 361
            +EC      C +   C N  G++ CI   CP GY         ++ C +    CL
Sbjct: 2017 NECVALPGSC-SPGTCQNLEGSFRCI---CPPGYEVKSENCIDINECDEDPNICL 2067

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 42/109 (38%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  GF   G   C D+DECA ++    C+  QC+N  G++ C C  GFT    +  C D+
Sbjct: 1435 CSEGFTGDGFT-CSDVDECAENIN--LCENGQCLNVPGAYRCECEMGFTPASDSRSCQDI 1491

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
            DEC    +IC +   C N PG + CI   C DGY  D        NCTD
Sbjct: 1492 DECSF-QNICVSGT-CNNLPGMFHCI---CDDGYELD----RTGGNCTD 1531

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 36/93 (38%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  GF       C DI+ECA +  P  C  +C+NT+GS+ C CP G+ L      C D+D
Sbjct: 2238 CNEGFEPGPMMNCEDINECAQN--PLLCALRCMNTFGSYECTCPIGYALREDQKMCKDLD 2295

Query: 200  ECRINSDICPNR-KFCINTPGNYSCIEPKCPDG 295
            EC      C +R   C N  G + CI   CP G
Sbjct: 2296 ECAEGLHDCESRGMMCKNLIGTFMCI---CPPG 2325

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 44/113 (38%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATD--VKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            C++GF  + D R C DIDEC+       G+C     N  G FHC+C  G+ L      C 
Sbjct: 1475 CEMGFTPASDSRSCQDIDECSFQNICVSGTCN----NLPGMFHCICDDGYELDRTGGNCT 1530

Query: 191  DVDECR--INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
            D+DEC   IN   C N   C+NTPG Y C    CP     DF+L      C D
Sbjct: 1531 DIDECADPIN---CVN-GLCVNTPGRYEC---NCPP----DFQLNPTGVGCVD 1572

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 39/106 (36%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  GF  S D+  C+D+DEC            C NT GS++CLC PGF L      C+D
Sbjct: 1917 ICHNGFKASQDQTMCMDVDECERHPCGNGT---CKNTVGSYNCLCYPGFEL-THNNDCLD 1972

Query: 194  VDEC-RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            +DEC      +C N + C N  G++ C+   C +GY      K C+
Sbjct: 1973 IDECSSFFGQVCRNGR-CFNEIGSFKCL---CNEGYELTPDGKNCI 2014

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            D++EC     PG C   QC+NT GSF C CP G+ L    ++C+D DEC I +  C N  
Sbjct: 2170 DVNECLES--PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGT 2226

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
             C N  G++ C    C +G+         + NC D
Sbjct: 2227 -CTNVIGSFEC---NCNEGFE-----PGPMMNCED 2252

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 32/81 (39%), Positives = 41/81 (50%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            C+D +EC+     GS    C NT GS+ C CP GF+    +  C DV+EC  + + C   
Sbjct: 2651 CVDENECSNPNACGSAS--CYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPC--N 2706

Query: 236  KFCINTPGNYSCIEPKCPDGY 298
              C NT G Y C    CP GY
Sbjct: 2707 YGCSNTEGGYLC---GCPPGY 2724

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
 Frame = +2

Query: 50   RGCIDIDECATD---VKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
            R CIDIDEC  +      G C+    NT GS+ C CPPG+    +T  C D++EC  N  
Sbjct: 805  RNCIDIDECLVNRLLCDNGLCR----NTPGSYSCTCPPGYVFRTETETCEDINECESNP- 859

Query: 221  ICPNRKFCINTPGNYSC 271
             C N   C N  G+++C
Sbjct: 860  -CVNGA-CRNNLGSFNC 874

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  GF  S +  C+D +EC     P  C +  CV+  GS+ C+C  GF        C+DV
Sbjct: 1877 CAAGFKLSPNGACVDRNECLEI--PNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDV 1934

Query: 197  DECRINSDICPNRKFCINTPGNYSCI 274
            DEC  +   C N   C NT G+Y+C+
Sbjct: 1935 DECERHP--CGNGT-CKNTVGSYNCL 1957

 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 36/106 (33%), Positives = 46/106 (43%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            CID +EC +       +  C NT GSF C C  GF+L    + C DVDEC  N      +
Sbjct: 2568 CIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRC---Q 2624

Query: 236  KFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQAS 373
              C N  G Y C    CP GY   ++   C+      +P     AS
Sbjct: 2625 HGCQNILGGYRC---GCPQGYIQHYQWNQCVDENECSNPNACGSAS 2667

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 33/90 (36%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  G+    +  CIDI+EC  D  P  C +  C NT G F CLCPPGF L     +C D
Sbjct: 2041 ICPPGYEVKSEN-CIDINECDED--PNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2097

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPK 283
                         + FC     N  C  PK
Sbjct: 2098 T-----------RQSFCFTNFENGKCSVPK 2116

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 28/81 (34%), Positives = 42/81 (51%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            C DIDEC+           C+N+ GS+ C C  GF L P    C+D +EC    ++C + 
Sbjct: 1847 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVC-SH 1904

Query: 236  KFCINTPGNYSCIEPKCPDGY 298
              C++  G+Y CI   C +G+
Sbjct: 1905 GLCVDLQGSYQCI---CHNGF 1922

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 27/61 (44%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
 Frame = +2

Query: 17  ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           ICK GF+ + + R C D+DEC T   PG C    C+N+ GSF C CPPG  +      C+
Sbjct: 641 ICKPGFVLAPNGRYCTDVDECQT---PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCV 697

Query: 191 D 193
           D
Sbjct: 698 D 698

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
 Frame = +2

Query: 41   SGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
            +G++ C   + C T   PG+  ++ +       C   PGFT    T K +D+DEC+    
Sbjct: 1770 AGNKPC---EPCPT---PGTADFKTI-------CGNIPGFTFDIHTGKAVDIDECKEIPG 1816

Query: 221  ICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
            IC N   CIN  G++ C   +CP G++++  L  C  +  C++    C   A  I
Sbjct: 1817 ICAN-GVCINQIGSFRC---ECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1867

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 25/58 (43%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV--DECRINSD 220
            C D++EC  +V PG C   +CVN+ GSFHC CP G TL      C+D+  ++C +  D
Sbjct: 952  CEDVNEC--EVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWD 1007

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
 Frame = +2

Query: 11   HEICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
            H IC  G+      G C DIDECA  +        CVNT G + C CPP F L P  + C
Sbjct: 1513 HCICDDGYELDRTGGNCTDIDECADPIN--CVNGLCVNTPGRYECNCPPDFQLNPTGVGC 1570

Query: 188  ID--VDECRINSDICPNRKFCINTPGNYSC 271
            +D  V  C +        KF     G+ SC
Sbjct: 1571 VDNRVGNCYL--------KFGPRGDGSLSC 1592

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 28/73 (38%), Positives = 38/73 (52%)
 Frame = +2

Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
           +C+ T  S+ C C  G+        CIDVDEC   S+ C N   C+NTPG+Y C   KC 
Sbjct: 508 RCIPTVSSYRCECNMGYK-QDANGDCIDVDEC--TSNPCTNGD-CVNTPGSYYC---KCH 560

Query: 290 DGYNFDFRLKACL 328
            G+      +AC+
Sbjct: 561 AGFQRTPTKQACI 573

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 10/100 (10%)
 Frame = +2

Query: 59   IDIDECATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECR 208
            I    C  ++   + + +C  T G+              CP G     K + C DV+EC 
Sbjct: 901  IQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARI-KGVTCEDVNECE 959

Query: 209  INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            +   +CPN + C+N+ G++ C   +CP+G   D   + CL
Sbjct: 960  VFPGVCPNGR-CVNSKGSFHC---ECPEGLTLDGTGRVCL 995

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
           C DIDEC+  + PG C+  +C NT GS+ C+CP G+       +CID
Sbjct: 315 CEDIDECS--IIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 359

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 37/116 (31%), Positives = 49/116 (42%), Gaps = 18/116 (15%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C  G+  S D R C DIDEC     PG C    C NT G++ C+CPP +        C+D
Sbjct: 1676 CPQGYYLSEDTRICEDIDECFAH--PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMD 1733

Query: 194  VDEC----RINSDICPN-------RKFC-----INTPGNYSCIEPKCPDGYNFDFR 313
            + +       N   C N       ++ C     +   GN  C EP CP     DF+
Sbjct: 1734 MRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAGNKPC-EP-CPTPGTADFK 1787

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
 Frame = +2

Query: 134  FHCLCP--PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFD 307
            ++ LCP   GF   P T+   D+DEC+    +C     CINT G++ C   +CP GY   
Sbjct: 1628 YYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQC---ECPQGYYLS 1683

Query: 308  FRLKAC 325
               + C
Sbjct: 1684 EDTRIC 1689

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C  G+++  +   C DI+EC ++         C N  GSF+C C PG  L    + CID
Sbjct: 836  CPPGYVFRTETETCEDINECESNPCVNGA---CRNNLGSFNCECSPGSKLSSTGLICID 891
>sp|Q61555|FBN2_MOUSE Fibrillin-2 precursor
          Length = 2907

 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 46/113 (40%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  G+  + DR GC DIDEC   +  G C  QC N+ GS+ C C  G+ L P    C D+
Sbjct: 1220 CNPGYQATPDRQGCTDIDECM--IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI 1277

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSP 352
            DEC  N DIC   + C N PG Y C+   C DG+     +K C+  N  D +P
Sbjct: 1278 DECENNPDICDGGQ-CTNIPGEYRCL---CYDGFMASMDMKTCIDVNECDLNP 1326

 Score = 83.2 bits (204), Expect = 9e-16
 Identities = 45/106 (42%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = +2

Query: 29   GFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDEC 205
            G I +G   C DI+EC     PG C Y +C NT GSF C C  GF L  +   C D+DEC
Sbjct: 1055 GDILTGRPFCKDINECKAF--PGMCTYGKCRNTIGSFKCRCNNGFALDMEERNCTDIDEC 1112

Query: 206  RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
            RI+ D+C     C+NTPG++ C   +C +GY   F +   + NC D
Sbjct: 1113 RISPDLC-GSGICVNTPGSFEC---ECFEGYESGFMM---MKNCMD 1151

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 40/106 (37%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
 Frame = +2

Query: 20   CKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            CK+G+        C+D+DEC+   KP  C + C NT GS+ C CP G+ L      C D+
Sbjct: 2469 CKVGYTMDISGTACVDLDECSQSPKP--CNFICKNTKGSYQCSCPRGYVLQEDGKTCKDL 2526

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
            DEC+     C  +  C+NT G ++C   KCP G  F     AC+ N
Sbjct: 2527 DECQTKQHNC--QFLCVNTLGGFTC---KCPPG--FTQHHTACIDN 2565

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 40/93 (43%), Positives = 54/93 (58%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C+ G++ +G + CID+DECA      S   QCVNT GS+ C C  GFT       C DVD
Sbjct: 1388 CREGWVGNGIK-CIDLDECANGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVD 1444

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
            EC  N+++C N + C+N PG Y C   +C  G+
Sbjct: 1445 ECAENTNLCENGQ-CLNVPGAYRC---ECEMGF 1473

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 43/130 (33%), Positives = 62/130 (47%)
 Frame = +2

Query: 20  CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
           C +G+    +  CID+DEC ++         CVNT GS++C C  GF   P    CID+D
Sbjct: 514 CNMGYKQDANGDCIDVDECTSNPCSNG---DCVNTPGSYYCKCHAGFQRTPTKQACIDID 570

Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASRI 379
           EC  N  +C N + C+N+ G++ CI        N  F L     NC D   +C T    +
Sbjct: 571 ECIQNGVLCKNGR-CVNSDGSFQCI-------CNAGFELTTDGKNCVDHD-ECTTTNMCL 621

Query: 380 QYVVVQMTGS 409
             + +   GS
Sbjct: 622 NGMCINEDGS 631

 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 53/163 (32%), Positives = 74/163 (45%), Gaps = 5/163 (3%)
 Frame = +2

Query: 50   RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
            + C+DIDEC  +  P  C+   CVNT GSF C CP G  L P    C+D++EC ++ ++C
Sbjct: 1147 KNCMDIDECERN--PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLC 1204

Query: 227  PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ--YVVV 394
             N K C+N  G Y C    C  GY      + C  +  C   +  C TQ +  +  Y   
Sbjct: 1205 RNGK-CVNMIGTYQC---SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECS 1260

Query: 395  QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
               G    P + R    + + ENN    +     NIP  Y  L
Sbjct: 1261 CSEGYALMP-DGRSCADIDECENNPDICDGGQCTNIPGEYRCL 1302

 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 42/120 (35%), Positives = 63/120 (52%), Gaps = 2/120 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            +C  GF+ S D + CID++EC  D+ P  C + +C NT GSF C C  G+++   T  C 
Sbjct: 1302 LCYDGFMASMDMKTCIDVNEC--DLNPNICMFGECENTKGSFICHCQLGYSVKKGTTGCT 1359

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
            DVDEC I +  C     C+N PG++ C    C +G+  +      L  C + + +C   A
Sbjct: 1360 DVDECEIGAHNCDMHASCLNVPGSFKC---SCREGWVGNGIKCIDLDECANGTHQCSINA 1416

 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 41/95 (43%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
 Frame = +2

Query: 20  CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
           C+ GFI +   G C D+DEC     PG CQ   C+NT GSF C CP G      T KC D
Sbjct: 261 CRPGFIPNIRTGACQDVDEC--QAIPGLCQGGNCINTVGSFECRCPAGHKQSETTQKCED 318

Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
           +DEC +   +C     C NT G+Y C+   CP G+
Sbjct: 319 IDECSVIPGVCETGD-CSNTVGSYFCL---CPRGF 349

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 38/80 (47%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DIDEC     PG CQ   C+NT+GSF C CP G+ L  +T  C D+DEC  +  +C    
Sbjct: 1643 DIDECQE--LPGLCQGGNCINTFGSFQCECPQGYYLSEETRICEDIDECFAHPGVC-GPG 1699

Query: 239  FCINTPGNYSCIEPKCPDGY 298
             C NT GNY+CI   CP  Y
Sbjct: 1700 TCYNTLGNYTCI---CPPEY 1716

 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 42/102 (41%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DIDEC   V P  C   QCVNT GSF C C  G+T+      C+D+DEC  +   C    
Sbjct: 2442 DIDECK--VMPSLCTNGQCVNTMGSFRCFCKVGYTMDISGTACVDLDECSQSPKPC--NF 2497

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
             C NT G+Y C    CP GY      K C  L  C  K   C
Sbjct: 2498 ICKNTKGSYQC---SCPRGYVLQEDGKTCKDLDECQTKQHNC 2536

 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 41/95 (43%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
 Frame = +2

Query: 17  ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           IC  GF  + D + C+D DEC T      C    C+N  GSF C+C PGF L P    C 
Sbjct: 594 ICNAGFELTTDGKNCVDHDECTTT---NMCLNGMCINEDGSFKCVCKPGFILAPNGRYCT 650

Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDG 295
           DVDEC+    IC N   CIN  G++ C    CP G
Sbjct: 651 DVDECQ-TPGICMN-GHCINNEGSFRC---DCPPG 680

 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
 Frame = +2

Query: 20   CKIGF-IWSGDRGCIDIDECATDVKPGSCQ-YQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C +G+ +    + C D+DECA  +     +   C N  G+F C+CPPG    P    C+D
Sbjct: 2272 CPVGYGLREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVD 2331

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
             +ECR    IC N + C+N  G+Y C   +C +G+        CL N
Sbjct: 2332 ENECRTKPGICENGR-CVNIIGSYRC---ECNEGFQSSSSGTECLDN 2374

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 44/123 (35%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
 Frame = +2

Query: 11   HEICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKC 187
            H +C  G   + D    DI+ECA D  P  C    C N  G++ C C  G+        C
Sbjct: 746  HGLCSSGIGITVDGR--DINECALD--PDICANGICENLRGTYRCNCNSGYEPDASGRNC 801

Query: 188  IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQ 367
            ID+DEC +N  +C N   C NTPG+YSC    CP GY      + C      +S  C+  
Sbjct: 802  IDIDECLVNRLLCDN-GLCRNTPGSYSC---TCPPGYVLPTETETCEDVNECESNPCVNG 857

Query: 368  ASR 376
            A R
Sbjct: 858  ACR 860

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 59   IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            +DIDEC     PG C    C+N  GSF C CP GF+     + C D+DEC    ++C   
Sbjct: 1800 VDIDECKEI--PGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 1857

Query: 236  KFCINTPGNYSCIEPKCPDGY 298
              CIN+PG+Y C   +C  G+
Sbjct: 1858 ADCINSPGSYRC---ECAAGF 1875

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 45/112 (40%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C++GF  + D R C DIDEC+       C +  C N  G FHC+C  G+ L      C D
Sbjct: 1469 CEMGFTPASDSRSCQDIDECSFQ---NICVFGTCNNLPGMFHCICDDGYELDRTGGNCTD 1525

Query: 194  VDECR--INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
            +DEC   IN   C N   C+NTPG Y C    CP     DF+L A    C D
Sbjct: 1526 IDECADPIN---CVN-GLCVNTPGRYEC---NCPP----DFQLNATGVGCVD 1566

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 2/117 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            +C  GF  + +  C+DIDEC++         +C N  GSF CLC  G+ L P    CID 
Sbjct: 1951 LCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDT 2010

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCL 361
            +EC      C +   C N  G++ CI   CP GY  + R + C  ++ C +    CL
Sbjct: 2011 NECVALPGSC-SPGTCQNLEGSFRCI---CPPGY--EVRSENCIDINECDEDPNICL 2061

 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 36/93 (38%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  GF       C DI+ECA +  P  C ++C+NT+GS+ C CP G+ L      C D+D
Sbjct: 2232 CNEGFEPGPMMNCEDINECAQN--PLLCAFRCMNTFGSYECTCPVGYGLREDQKMCKDLD 2289

Query: 200  ECRINSDICPNR-KFCINTPGNYSCIEPKCPDG 295
            EC      C +R   C N  G + CI   CP G
Sbjct: 2290 ECAEGLHDCESRGMMCKNLIGTFMCI---CPPG 2319

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
 Frame = +2

Query: 20   CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C+ GF + +    C D+DEC  + +   CQ+ C N  G + C CP G   + +  +C+D 
Sbjct: 2592 CQRGFSLDASGLNCEDVDECDGNHR---CQHGCQNILGGYRCGCPHGDVQHYQWNQCVDE 2648

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
            +EC  N   C +   C NT G+Y C    CP G++FD    AC  ++ C+     C
Sbjct: 2649 NECS-NPGACGSAS-CYNTLGSYKCA---CPSGFSFDQFSSACHDVNECSSSKNPC 2699

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C  G+    D R C DIDEC  +  P  C   QC N  G + CLC  GF        CID
Sbjct: 1261 CSEGYALMPDGRSCADIDECENN--PDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 1318

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
            V+EC +N +IC   + C NT G++ C    C  GY+    +K   + CTD
Sbjct: 1319 VNECDLNPNICMFGE-CENTKGSFIC---HCQLGYS----VKKGTTGCTD 1360

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 42/109 (38%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  GF   G   C D+DECA +     C+  QC+N  G++ C C  GFT    +  C D+
Sbjct: 1429 CSEGFTGDGFT-CSDVDECAENTN--LCENGQCLNVPGAYRCECEMGFTPASDSRSCQDI 1485

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
            DEC    +IC     C N PG + CI   C DGY  D        NCTD
Sbjct: 1486 DECSF-QNICVFGT-CNNLPGMFHCI---CDDGYELD----RTGGNCTD 1525

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  GF  S D+  C+D+DEC    +       C NT GS++CLC PGF L      C+D
Sbjct: 1911 ICNNGFKASQDQTMCMDVDECE---RHPCANGTCKNTVGSYNCLCYPGFEL-THNNDCLD 1966

Query: 194  VDEC-RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            +DEC      +C N + C N  G++ C+   C +GY      K C+
Sbjct: 1967 IDECSSFFGQVCRNGR-CFNEIGSFKCL---CNEGYELTPDGKNCI 2008

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 33/82 (40%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPN 232
            C+D +EC+    PG+C    C NT GS+ C CP GF+    +  C DV+EC  + + C  
Sbjct: 2645 CVDENECSN---PGACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCSY 2701

Query: 233  RKFCINTPGNYSCIEPKCPDGY 298
               C NT G Y C    CP GY
Sbjct: 2702 G--CSNTEGGYLC---GCPPGY 2718

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 36/95 (37%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            D++EC     PG C   QC+NT GSF C CP G+ L    ++C+D DEC I +  C N  
Sbjct: 2164 DVNECLES--PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGT 2220

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
             C N  G   C E  C +G+         + NC D
Sbjct: 2221 -CTNVIG---CFECTCNEGFE-----PGPMMNCED 2246

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
 Frame = +2

Query: 50   RGCIDIDECATD---VKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
            R CIDIDEC  +      G C+    NT GS+ C CPPG+ L  +T  C DV+EC  N  
Sbjct: 799  RNCIDIDECLVNRLLCDNGLCR----NTPGSYSCTCPPGYVLPTETETCEDVNECESNP- 853

Query: 221  ICPNRKFCINTPGNYSC 271
             C N   C N  G++ C
Sbjct: 854  -CVNGA-CRNNLGSFHC 868

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  GF  S +  C+D +EC     P  C +  CV+  GS+ C+C  GF        C+DV
Sbjct: 1871 CAAGFKLSPNGACVDRNECLEI--PNVCSHGLCVDLQGSYQCICNNGFKASQDQTMCMDV 1928

Query: 197  DECRINSDICPNRKFCINTPGNYSCI 274
            DEC  +   C N   C NT G+Y+C+
Sbjct: 1929 DECERHP--CANGT-CKNTVGSYNCL 1951

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 28/81 (34%), Positives = 42/81 (51%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            C DIDEC+           C+N+ GS+ C C  GF L P    C+D +EC    ++C + 
Sbjct: 1841 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVC-SH 1898

Query: 236  KFCINTPGNYSCIEPKCPDGY 298
              C++  G+Y CI   C +G+
Sbjct: 1899 GLCVDLQGSYQCI---CNNGF 1916

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 32/90 (35%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  G+    +  CIDI+EC  D  P  C +  C NT G F C+CPPGF L     +C D
Sbjct: 2035 ICPPGYEVRSEN-CIDINECDED--PNICLFGSCTNTPGGFQCICPPGFVLSDNGRRCFD 2091

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPK 283
                         + FC     N  C  PK
Sbjct: 2092 T-----------RQSFCFTNFENGKCSVPK 2110

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 27/61 (44%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
 Frame = +2

Query: 17  ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           +CK GFI + + R C D+DEC T   PG C    C+N  GSF C CPPG  +      C+
Sbjct: 635 VCKPGFILAPNGRYCTDVDECQT---PGICMNGHCINNEGSFRCDCPPGLAVGVDGRVCV 691

Query: 191 D 193
           D
Sbjct: 692 D 692

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
 Frame = +2

Query: 59   IDIDECATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECR 208
            I  + C  ++   + + +C  T G               CP GF    K + C DV+EC 
Sbjct: 895  IQDNRCEVNINGATLKSECCATLGGAWGSPCERCELDAACPRGFARI-KGVTCEDVNECE 953

Query: 209  INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            +   +CPN + C+N+ G++ C   +CP+G   D   + CL
Sbjct: 954  VFPGVCPNGR-CVNSKGSFHC---ECPEGLTLDGTGRVCL 989

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
 Frame = +2

Query: 41   SGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
            +G++ C   + C T   PG+  ++ +       C   PGFT    T K +D+DEC+    
Sbjct: 1764 AGNKPC---EPCPT---PGTADFKTI-------CGNIPGFTFDIHTGKAVDIDECKEIPG 1810

Query: 221  ICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
            IC N   CIN  G++ C   +CP G++++  L  C  +  C++    C   A  I
Sbjct: 1811 ICAN-GVCINQIGSFRC---ECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1861

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 26/60 (43%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  GF       C D++EC  +V PG C   +CVN+ GSFHC CP G TL      C+D+
Sbjct: 934  CPRGFARIKGVTCEDVNEC--EVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDI 991

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 28/73 (38%), Positives = 38/73 (52%)
 Frame = +2

Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
           +C+ T  S+ C C  G+        CIDVDEC   S+ C N   C+NTPG+Y C   KC 
Sbjct: 502 RCIPTVSSYRCRCNMGYK-QDANGDCIDVDEC--TSNPCSNGD-CVNTPGSYYC---KCH 554

Query: 290 DGYNFDFRLKACL 328
            G+      +AC+
Sbjct: 555 AGFQRTPTKQACI 567

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
           C DIDEC+  V PG C+   C NT GS+ CLCP GF       +CID
Sbjct: 316 CEDIDECS--VIPGVCETGDCSNTVGSYFCLCPRGFVTSTDGSRCID 360

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 36/116 (31%), Positives = 49/116 (42%), Gaps = 18/116 (15%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C  G+  S + R C DIDEC     PG C    C NT G++ C+CPP +        C+D
Sbjct: 1670 CPQGYYLSEETRICEDIDECFAH--PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMD 1727

Query: 194  VDEC----RINSDICPN-------RKFC-----INTPGNYSCIEPKCPDGYNFDFR 313
            + +       N   C N       ++ C     +   GN  C EP CP     DF+
Sbjct: 1728 MRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAGNKPC-EP-CPTPGTADFK 1781

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 32/116 (27%), Positives = 43/116 (37%), Gaps = 14/116 (12%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPP--------------G 157
            C + F   GD       E    V   SC       +G+    CPP              G
Sbjct: 1572 CYLKFGPRGDGSLSCNTEAGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEHYTLCPGGEG 1631

Query: 158  FTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
            F   P T+   D+DEC+    +C     CINT G++ C   +CP GY      + C
Sbjct: 1632 FRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQC---ECPQGYYLSEETRIC 1683

 Score = 38.5 bits (88), Expect = 0.024
 Identities = 26/99 (26%), Positives = 38/99 (38%), Gaps = 18/99 (18%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV-----------DE 202
            C D++EC ++         C N  GSFHC C PG  L    + CID            + 
Sbjct: 843  CEDVNECESNPCVNGA---CRNNLGSFHCECSPGSKLSSTGLICIDSLKGTCWLNIQDNR 899

Query: 203  CRIN-------SDICPNRKFCINTPGNYSCIEPKCPDGY 298
            C +N       S+ C        +P     ++  CP G+
Sbjct: 900  CEVNINGATLKSECCATLGGAWGSPCERCELDAACPRGF 938
>sp|O88281|EGFL3_RAT Multiple EGF-like-domain protein 3 precursor (Multiple epidermal
           growth factor-like domains 6)
          Length = 1574

 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 51/126 (40%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
 Frame = +2

Query: 38  WS---GDRGCI-DIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDEC 205
           WS   G  GC+ D+DECA+    G C+  C NT G F+C CPPG+ L      C DVDEC
Sbjct: 111 WSQKPGQEGCLSDVDECAS--ANGGCEGPCCNTVGGFYCRCPPGYQLQGDGKTCQDVDEC 168

Query: 206 RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL--SNCTDKSPKCLTQASRI 379
           R ++  C +R  C+NTPG+Y C   +C  G+      + CL  S+CT  +  C  Q   +
Sbjct: 169 RAHNGGCQHR--CVNTPGSYLC---ECKPGFRLHTDGRTCLAISSCTLGNGGCQHQC--V 221

Query: 380 QYVVVQ 397
           Q  V Q
Sbjct: 222 QLTVTQ 227

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 37/105 (35%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
 Frame = +2

Query: 20  CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
           C  G+    D + CIDID+CA       CQ  C NT G + C C  G+ L      C DV
Sbjct: 360 CPRGYELDEDQKTCIDIDDCANSP---CCQQACANTPGGYECSCFAGYRLNTDGCGCEDV 416

Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS 331
           DEC      C +   C N  G++ C    C  GY  D   + C S
Sbjct: 417 DECASGHGGCEHH--CSNLAGSFQCF---CEAGYRLDEDRRGCTS 456

 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 38/121 (31%), Positives = 53/121 (43%), Gaps = 4/121 (3%)
 Frame = +2

Query: 20  CKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
           C  G+  + DR  C D+DECA  +    C + C+NT GSF C+C  G+ L     +C  +
Sbjct: 273 CHPGYQLAADRKTCEDVDECALGL--AQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRI 330

Query: 197 DECRINSDICPN---RKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQ 367
           +   +NS    N      C +T     C    CP GY  D   K C+      +  C  Q
Sbjct: 331 EMEIVNSCEAGNGGCSHGCSHTSTGPLC---TCPRGYELDEDQKTCIDIDDCANSPCCQQ 387

Query: 368 A 370
           A
Sbjct: 388 A 388

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 30/92 (32%), Positives = 40/92 (43%)
 Frame = +2

Query: 50  RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICP 229
           R C+    CA     G C + C    G  HC C PG+ L      C DVDEC +    C 
Sbjct: 243 RRCVRRSPCAEG--NGGCMHICQELRGLAHCGCHPGYQLAADRKTCEDVDECALGLAQCA 300

Query: 230 NRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
           +   C+NT G++ C+   C  GY      + C
Sbjct: 301 HG--CLNTQGSFKCV---CHAGYELGADGRQC 327

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 21/56 (37%), Positives = 30/56 (53%)
 Frame = +2

Query: 53  GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
           GC D+DECA+    G C++ C N  GSF C C  G+ L      C  ++E  ++ D
Sbjct: 412 GCEDVDECASG--HGGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCTSLEESVVDLD 465

 Score = 30.0 bits (66), Expect = 8.7
 Identities = 21/82 (25%), Positives = 32/82 (39%), Gaps = 11/82 (13%)
 Frame = +2

Query: 74  CATDVKPGSCQYQCVNTY---GSFH-CLCPPGFTLYPKTMKC-------IDVDECRINSD 220
           C    +   CQ +C + +   G  H C C PG    P + +C          ++C     
Sbjct: 677 CKAGFQGERCQAECESGFFGPGCRHRCTCQPGVACDPVSGECRTQCPPGYQGEDC---GQ 733

Query: 221 ICPNRKFCINTPGNYSCIEPKC 286
            CP   F +N  G+ SC+   C
Sbjct: 734 ECPVGTFGVNCSGSCSCVGAPC 755
>sp|P35555|FBN1_HUMAN Fibrillin-1 precursor
          Length = 2871

 Score = 87.0 bits (214), Expect = 6e-17
 Identities = 47/118 (39%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
 Frame = +2

Query: 20   CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  G+  + DR  C+DIDEC+  +  G C+  C N+ GS+ C C PGF L P    C D+
Sbjct: 1182 CNPGYHSTPDRLFCVDIDECS--IMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDI 1239

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSPK-CLT 364
            DEC  N +IC   + C N PG Y C+   C DG+     +K C+  N  D +P  CL+
Sbjct: 1240 DECEDNPNICDGGQ-CTNIPGEYRCL---CYDGFMASEDMKTCVDVNECDLNPNICLS 1293

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 41/95 (43%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DI+EC   + P  C + +C NT GSF C C  GF L  +   C D+DECRI+ D+C  R 
Sbjct: 1028 DINECK--MIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC-GRG 1084

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
             C+NTPG++ C   KC +GY   F +   + NC D
Sbjct: 1085 QCVNTPGDFEC---KCDEGYESGFMM---MKNCMD 1113

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 40/113 (35%), Positives = 55/113 (48%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  GFI S +  CID+DECA+         QC+NT GSF C C  G+ + P    C+D++
Sbjct: 1916 CNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDIN 1975

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
            EC +    C     C N  G+Y CI   CP GY+        +  C ++   C
Sbjct: 1976 ECLLEPRKCAPGT-CQNLDGSYRCI---CPPGYSLQNEKCEDIDECVEEPEIC 2024

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 52/163 (31%), Positives = 75/163 (46%), Gaps = 5/163 (3%)
 Frame = +2

Query: 50   RGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
            + C+DIDEC  D  P  C+   C NT GS+ C CPPG  L P    CID++EC +++ +C
Sbjct: 1109 KNCMDIDECQRD--PLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLC 1166

Query: 227  PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ--YVVV 394
            PN + C+N  G Y C    C  GY+       C  +  C+  +  C T  +  +  Y   
Sbjct: 1167 PNGR-CVNLIGKYQC---ACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECS 1222

Query: 395  QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
               G    P + R    + + E+N    +     NIP  Y  L
Sbjct: 1223 CQPGFALMP-DQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264

 Score = 73.9 bits (180), Expect = 5e-13
 Identities = 42/95 (44%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
 Frame = +2

Query: 20  CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
           C+ GFI +   G C D+DEC     PG CQ   C+NT GSF C CP G  L   + KC D
Sbjct: 231 CRRGFIPNIRTGACQDVDEC--QAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED 288

Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
           +DEC     IC   + C NT  +Y C   KCP G+
Sbjct: 289 IDECSTIPGICEGGE-CTNTVSSYFC---KCPPGF 319

 Score = 73.9 bits (180), Expect = 5e-13
 Identities = 43/119 (36%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
 Frame = +2

Query: 11   HEICKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
            H ICK G+        C+D++EC    KP  C + C NT GS+ C CP G+ L      C
Sbjct: 2426 HCICKTGYTPDITGTSCVDLNECNQAPKP--CNFICKNTEGSYQCSCPKGYILQEDGRSC 2483

Query: 188  IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN--CTDKSPKC 358
             D+DEC      C  +  C+NT G ++C   KCP G  F     +C+ N  CT     C
Sbjct: 2484 KDLDECATKQHNC--QFLCVNTIGGFTC---KCPPG--FTQHHTSCIDNNECTSDINLC 2535

 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 46/129 (35%), Positives = 69/129 (53%), Gaps = 10/129 (7%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVK---PGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
            C  G+  + D R C+DI+EC  + +   PG+CQ    N  GS+ C+CPPG++L  +  KC
Sbjct: 1958 CNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQ----NLDGSYRCICPPGYSL--QNEKC 2011

Query: 188  IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC----LSNCTDK--S 349
             D+DEC    +IC     C NT G++ C+   CP+G++     + C    +S C  K   
Sbjct: 2012 EDIDECVEEPEICALGT-CSNTEGSFKCL---CPEGFSLSSSGRRCQDLRMSYCYAKFEG 2067

Query: 350  PKCLTQASR 376
             KC +  SR
Sbjct: 2068 GKCSSPKSR 2076

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 37/83 (44%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
 Frame = +2

Query: 59   IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            +DIDEC     PG C+   C+N  GSF C CP GF    K + C D+DEC+ N  +C   
Sbjct: 1765 VDIDECREI--PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRN 1821

Query: 236  KFCINTPGNYSCIEPKCPDGYNF 304
              CINT G+Y C    C  GY F
Sbjct: 1822 AECINTAGSYRC---DCKPGYRF 1841

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 42/106 (39%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
 Frame = +2

Query: 20   CKIGF-IWSGDRGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMK-CI 190
            C  GF + S +R C DIDEC   + P  C + QCVNT G F C C  G+      MK C+
Sbjct: 1055 CDSGFALDSEERNCTDIDECR--ISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCM 1112

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            D+DEC+ +  +C     C NT G+Y C   +CP G+     + AC+
Sbjct: 1113 DIDECQRDPLLC-RGGVCHNTEGSYRC---ECPPGHQLSPNISACI 1154

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 4/109 (3%)
 Frame = +2

Query: 20   CKIGFIWSGDRG-CIDIDECATDVKPGSC---QYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
            C +G++   DR  C D DEC  +     C   Q +C N  G++ C+C PG+   P    C
Sbjct: 2232 CPVGYVLREDRRMCKDEDEC--EEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGC 2289

Query: 188  IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
            +D +EC+    IC N + C+NT G+Y+C   +C DG+        CL N
Sbjct: 2290 VDENECQTKPGICENGR-CLNTRGSYTC---ECNDGFTASPNQDECLDN 2334

 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 38/94 (40%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C+ GF       C DI+ECA +  P  C ++CVNTYGS+ C CP G+ L      C D D
Sbjct: 2192 CEEGFEPGPMMTCEDINECAQN--PLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDED 2249

Query: 200  ECRINSDICPNRKF-CINTPGNYSCIEPKCPDGY 298
            EC      C  ++  C N  G Y CI   C  GY
Sbjct: 2250 ECEEGKHDCTEKQMECKNLIGTYMCI---CGPGY 2280

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 39/102 (38%), Positives = 52/102 (50%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  G+I  G + C D+DEC+      S    C NT GS+ CLC  G+T       C D+D
Sbjct: 1350 CSPGWIGDGIK-CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLD 1406

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
            EC  N ++C N + C+N PG Y C   +C  G+      KAC
Sbjct: 1407 ECSENLNLCGNGQ-CLNAPGGYRC---ECDMGFVPSADGKAC 1444

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DIDEC     PG CQ  +C+NT+GSF C CP G+ L   T  C DV+EC       P   
Sbjct: 1606 DIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT- 1662

Query: 239  FCINTPGNYSCIEPKCPDGYN--------FDFRLKACLSNCTDKSPKC 358
             C NT GNY+CI   CP  Y          D R   C  N    +  C
Sbjct: 1663 -CYNTVGNYTCI---CPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 45/118 (38%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
 Frame = +2

Query: 17   ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            +C  GF  + D+  C+DI+EC  D         C NT GSF+C C  GF L      CID
Sbjct: 1875 LCHTGFKTNDDQTMCLDINECERDACGNGT---CRNTIGSFNCRCNHGFIL-SHNNDCID 1930

Query: 194  VDECRI-NSDICPNRKFCINTPGNYSCIEPKCPDGYNF--DFRLKACLSNCTDKSPKC 358
            VDEC   N ++C N + CINT G++ C   +C +GY    D R    ++ C  +  KC
Sbjct: 1931 VDECASGNGNLCRNGQ-CINTVGSFQC---QCNEGYEVAPDGRTCVDINECLLEPRKC 1984

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 4/134 (2%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DI+ECA D  P  C    C N  G++ C+C  G+ +      C+D++EC +NS +C N +
Sbjct: 723  DINECALD--PDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ 780

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLT---QASRIQYVVVQMTGS 409
             C NTPG++ C    CP G+ +   LK C      +S  C+    + S   ++    + S
Sbjct: 781  -CRNTPGSFVC---TCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSES 836

Query: 410  MAQPVEVRVINTMK 451
               P +   I T+K
Sbjct: 837  TLDPTKTICIETIK 850

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 2/120 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            +C  GF+ S D + C+D++EC  D+ P  C    C NT GSF C C  G++       C 
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC--DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
            D++EC I +  C     C NT G++ C    C  G+  D      L  C++ +  C   A
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKC---SCSPGWIGDGIKCTDLDECSNGTHMCSQHA 1378

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 34/88 (38%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
 Frame = +2

Query: 11  HEICKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
           H +C  GF  + D + C D+DEC+  ++       C+N  GSF C+C PGF L      C
Sbjct: 554 HCVCNAGFHVTRDGKNCEDMDECS--IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611

Query: 188 IDVDECRINSDICPNRKFCINTPGNYSC 271
            D++EC     IC N + C+NT G+Y C
Sbjct: 612 KDINECE-TPGICMNGR-CVNTDGSYRC 637

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 36/102 (35%), Positives = 50/102 (49%)
 Frame = +2

Query: 20  CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
           C  GF       CID+DEC  +   G    +C+N  GS+ C C  G+       +C D+D
Sbjct: 476 CNKGFQLDLRGECIDVDECEKNPCAGG---ECINNQGSYTCQCRAGYQSTLTRTECRDID 532

Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
           EC  N  IC N + CINT G++ C+   C  G++     K C
Sbjct: 533 ECLQNGRICNNGR-CINTDGSFHCV---CNAGFHVTRDGKNC 570

 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 39/112 (34%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
 Frame = +2

Query: 29   GFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECR 208
            GF+ +G     DIDEC   +       +CVN  GS+HC+C  G+T       C+D++EC 
Sbjct: 2395 GFMTNG----ADIDECKV-IHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC- 2448

Query: 209  INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
             N    P    C NT G+Y C    CP GY      ++C  L  C  K   C
Sbjct: 2449 -NQAPKPCNFICKNTEGSYQC---SCPKGYILQEDGRSCKDLDECATKQHNC 2496

 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
 Frame = +2

Query: 20   CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C+ GF +      C D+DEC  + +   CQ+ C N  G + C CP G+  + +  +C+D 
Sbjct: 2552 CQRGFSLDQTGSSCEDVDECEGNHR---CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
            +EC +++ IC     C NT G+Y C+   CP G+ ++     C  ++ C      C
Sbjct: 2609 NEC-LSAHICGGAS-CHNTLGSYKCM---CPAGFQYEQFSGGCQDINECGSAQAPC 2659

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 43/116 (37%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C +GF+ S D + C DIDEC+    P  C +  C N  G F C C  G+ L      C D
Sbjct: 1431 CDMGFVPSADGKACEDIDECSL---PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD 1487

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD-KSPKC 358
            V+EC ++   C +   C+NTPG+Y C    CP     DF L      C D +S  C
Sbjct: 1488 VNEC-LDPTTCISGN-CVNTPGSYIC---DCPP----DFELNPTRVGCVDTRSGNC 1534

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            CK G+ ++    C D +EC     P  C + QC++T GSF+CLC  GF        C+D+
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEI--PNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDI 1892

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
            +EC    D C N   C NT G+++C   +C  G+
Sbjct: 1893 NEC--ERDACGNGT-CRNTIGSFNC---RCNHGF 1920

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
 Frame = +2

Query: 17  ICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           IC  G+ + S  + C+DI+EC  +     C   QC NT GSF C CP GF   P    C 
Sbjct: 749 ICNSGYEVDSTGKNCVDINECVLNSL--LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806

Query: 191 DVDECRINSDICPNRKFCINTPGNYSC 271
           D+DEC   S  C N   C N+PG++ C
Sbjct: 807 DIDEC--ESSPCIN-GVCKNSPGSFIC 830

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 45/158 (28%), Positives = 62/158 (39%), Gaps = 48/158 (30%)
 Frame = +2

Query: 29   GFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPK---------- 175
            G I   D   +D+DEC    +P  C++ QC+NT GS+ C CP G+TL             
Sbjct: 2116 GIIVGPDDSAVDMDECK---EPDVCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECSV 2172

Query: 176  ----------------------------TMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
                                         M C D++EC  N  +C  R  C+NT G+Y C
Sbjct: 2173 GNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYGSYEC 2230

Query: 272  IEPKCPDGYNFDFRLKACLS---------NCTDKSPKC 358
               KCP GY      + C           +CT+K  +C
Sbjct: 2231 ---KCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMEC 2265

 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 33/81 (40%), Positives = 46/81 (56%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
           C DIDEC  + +  +   +C+NT GSFHC+C  GF +      C D+DEC I  ++C N 
Sbjct: 528 CRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR-NMCLN- 584

Query: 236 KFCINTPGNYSCIEPKCPDGY 298
             CIN  G++ CI   C  G+
Sbjct: 585 GMCINEDGSFKCI---CKPGF 602

 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 34/91 (37%), Positives = 43/91 (47%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            CID +EC +D+     +  C NT GSF C C  GF+L      C DVDEC  N      +
Sbjct: 2522 CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRC---Q 2578

Query: 236  KFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
              C N  G Y C    CP GY   ++   C+
Sbjct: 2579 HGCQNIIGGYRC---SCPQGYLQHYQWNQCV 2606

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 43/131 (32%), Positives = 59/131 (45%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            +CK G+   G   C D+DEC+ ++       QC+N  G + C C  GF        C D+
Sbjct: 1390 LCKEGYTGDGFT-CTDLDECSENLNLCG-NGQCLNAPGGYRCECDMGFVPSADGKACEDI 1447

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
            DEC +  +IC     C N PG + C   +C  GY  D        NCTD + +CL   + 
Sbjct: 1448 DECSL-PNICVFGT-CHNLPGLFRC---ECEIGYELD----RSGGNCTDVN-ECLDPTTC 1497

Query: 377  IQYVVVQMTGS 409
            I    V   GS
Sbjct: 1498 ISGNCVNTPGS 1508

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 25/48 (52%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
           C DIDEC+T   PG C+  +C NT  S+ C CPPGF   P   +CIDV
Sbjct: 286 CEDIDECSTI--PGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            IC  G+    D  GC+D +EC T  KPG C+  +C+NT GS+ C C  GFT  P   +C+
Sbjct: 2275 ICGPGYQRRPDGEGCVDENECQT--KPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2332

Query: 191  DVDECRINSDICPN 232
            D  E    +++  N
Sbjct: 2333 DNREGYCFTEVLQN 2346

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 28/61 (45%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  G+       C DIDEC  +V PG C+   CVNT GSF C CP G TL      C+D
Sbjct: 895  ICGKGYSRIKGTQCEDIDEC--EVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD 952

Query: 194  V 196
            +
Sbjct: 953  I 953

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 28/72 (38%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
 Frame = +2

Query: 20   CKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C+IG+      G C D++EC   + P +C    CVNT GS+ C CPP F L P  + C+D
Sbjct: 1472 CEIGYELDRSGGNCTDVNEC---LDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVD 1528

Query: 194  VDECRINSDICP 229
                    DI P
Sbjct: 1529 TRSGNCYLDIRP 1540

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
 Frame = +2

Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
           +C+ T GS+ C C  GF L  +  +CIDVDEC  N   C   + CIN  G+Y+C   +C 
Sbjct: 464 RCIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNP--CAGGE-CINNQGSYTC---QCR 516

Query: 290 DGYNFDFRLKAC--LSNCTDKSPKC 358
            GY        C  +  C      C
Sbjct: 517 AGYQSTLTRTECRDIDECLQNGRIC 541

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 28/61 (45%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
 Frame = +2

Query: 17  ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           ICK GF  + D R C DI+EC T   PG C   +CVNT GS+ C C PG  +      C+
Sbjct: 597 ICKPGFQLASDGRYCKDINECET---PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653

Query: 191 D 193
           D
Sbjct: 654 D 654

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 26/61 (42%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  G+    ++ C DIDEC  +  P  C    C NT GSF CLCP GF+L     +C D
Sbjct: 1999 ICPPGYSLQNEK-CEDIDECVEE--PEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQD 2055

Query: 194  V 196
            +
Sbjct: 2056 L 2056

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
 Frame = +2

Query: 74   CATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECRINSDI 223
            C  ++   + + QC ++ G+             +C  G++    T +C D+DEC +   +
Sbjct: 862  CEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT-QCEDIDECEVFPGV 920

Query: 224  CPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            C N   C+NT G++ C   +CP G   D   + CL
Sbjct: 921  CKN-GLCVNTRGSFKC---QCPSGMTLDATGRICL 951

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = +2

Query: 17   ICKIGFIWSG-DRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGF 160
            +C  GF +     GC DI+EC +   P  C Y C NT G + C CPPG+
Sbjct: 2632 MCPAGFQYEQFSGGCQDINECGSAQAP--CSYGCSNTEGGYLCGCPPGY 2678

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
 Frame = +2

Query: 116  VNTYGSFHCLCP--PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
            VNT   +  LCP   GF   P T+   D+DEC+    +C   K CINT G++ C   +CP
Sbjct: 1580 VNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-CINTFGSFQC---RCP 1634

Query: 290  DGYNFDFRLKAC 325
             GY  +   + C
Sbjct: 1635 TGYYLNEDTRVC 1646

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
 Frame = +2

Query: 101  CQYQCVNTYGSFHCLCP---PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
            C+   + +   F  LC    PGF +   T   +D+DECR    +C N   CIN  G++ C
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRC 1791

Query: 272  IEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
               +CP G+ ++ +L  C  +  C    P C   A  I
Sbjct: 1792 ---ECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECI 1825
>sp|P98133|FBN1_BOVIN Fibrillin-1 precursor (MP340)
          Length = 2871

 Score = 87.0 bits (214), Expect = 6e-17
 Identities = 47/118 (39%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
 Frame = +2

Query: 20   CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  G+  + DR  C+DIDEC+  +  G C+  C N+ GS+ C C PGF L P    C D+
Sbjct: 1182 CNPGYHSTPDRLFCVDIDECS--IMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDI 1239

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSPK-CLT 364
            DEC  N +IC   + C N PG Y C+   C DG+     +K C+  N  D +P  CL+
Sbjct: 1240 DECEDNPNICDGGQ-CTNIPGEYRCL---CYDGFMASEDMKTCVDVNECDLNPNICLS 1293

 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 44/104 (42%), Positives = 59/104 (56%), Gaps = 1/104 (0%)
 Frame = +2

Query: 35   IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRI 211
            I +G R   DI+EC   + P  C + +C NT GSF C C  GF L  +   C D+DECRI
Sbjct: 1019 ITNGKRFFKDINECK--MIPNLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRI 1076

Query: 212  NSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
            + D+C  R  C+NTPG++ C   KC +GY   F +   + NC D
Sbjct: 1077 SPDLC-GRGQCVNTPGDFEC---KCDEGYESGFMM---MKNCMD 1113

 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 41/113 (36%), Positives = 56/113 (49%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  GFI S +  CID+DECAT         QC+NT GSF C C  G+ + P    C+D++
Sbjct: 1916 CNHGFILSHNNDCIDVDECATGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDIN 1975

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
            EC ++   C     C N  G+Y CI   CP GY+        +  C ++   C
Sbjct: 1976 ECLLDPRKCAPGT-CQNLDGSYRCI---CPPGYSLQNDKCEDIDECVEEPEIC 2024

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 51/163 (31%), Positives = 76/163 (46%), Gaps = 5/163 (3%)
 Frame = +2

Query: 50   RGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
            + C+DIDEC  D  P  C+   C+NT GS+ C CPPG  L P    CID++EC +++ +C
Sbjct: 1109 KNCMDIDECQRD--PLLCRGGVCLNTEGSYRCECPPGHQLAPNISACIDINECELSAHLC 1166

Query: 227  PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ--YVVV 394
            P+ + C+N  G Y C    C  GY+       C  +  C+  +  C T  +  +  Y   
Sbjct: 1167 PHGR-CVNLIGKYQC---ACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECS 1222

Query: 395  QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
               G    P + R    + + E+N    +     NIP  Y  L
Sbjct: 1223 CQPGFALMP-DQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 48/129 (37%), Positives = 69/129 (53%), Gaps = 10/129 (7%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVK---PGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
            C  G+  + D R C+DI+EC  D +   PG+CQ    N  GS+ C+CPPG++L  +  KC
Sbjct: 1958 CNEGYEVAPDGRTCVDINECLLDPRKCAPGTCQ----NLDGSYRCICPPGYSL--QNDKC 2011

Query: 188  IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC----LSNCTDK--S 349
             D+DEC    +IC     C NT G++ C+   CPDG++     + C    +S C  K   
Sbjct: 2012 EDIDECVEEPEICALGT-CSNTEGSFKCL---CPDGFSLSSTGRRCQDLRMSYCYAKFEG 2067

Query: 350  PKCLTQASR 376
             KC +  SR
Sbjct: 2068 GKCSSPKSR 2076

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 44/119 (36%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
 Frame = +2

Query: 11   HEICKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
            H ICK G+        C+D++EC    KP  C + C NT GS+ C CP G+ L      C
Sbjct: 2426 HCICKTGYTPDITGTACVDLNECNQAPKP--CNFICKNTEGSYQCSCPKGYILQEDGRSC 2483

Query: 188  IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN--CTDKSPKC 358
             D+DEC      C  +  C+NT G+++C   KCP G  F     AC+ N  CT     C
Sbjct: 2484 KDLDECATKQHNC--QFLCVNTIGSFTC---KCPPG--FTQHHTACIDNNECTSDINLC 2535

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 41/95 (43%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
 Frame = +2

Query: 20  CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
           C+ GFI +   G C D+DEC     PG CQ   C+NT GSF C CP G      + KC D
Sbjct: 231 CRRGFIPNIRTGACQDVDEC--QAIPGLCQGGNCINTVGSFECKCPAGHKFNEVSQKCED 288

Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
           +DEC     IC   + C NT  +Y C   KCP G+
Sbjct: 289 IDECSTIPGICDGGE-CTNTVSSYFC---KCPPGF 319

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 37/83 (44%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
 Frame = +2

Query: 59   IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            +DIDEC     PG C+   C+N  GSF C CP GF    K + C D+DEC+ N  +C   
Sbjct: 1765 VDIDECREI--PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRN 1821

Query: 236  KFCINTPGNYSCIEPKCPDGYNF 304
              CINT G+Y C    C  GY F
Sbjct: 1822 AECINTAGSYRC---DCKPGYRF 1841

 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 38/102 (37%), Positives = 52/102 (50%)
 Frame = +2

Query: 20  CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
           C  GF       CID+DEC  +   G    +C+NT GS+ C C PG+       +C D+D
Sbjct: 476 CNKGFQLDLRGECIDVDECEKNPCAGG---ECINTQGSYTCQCRPGYQSTLTRTECRDID 532

Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
           EC  N  IC N + CINT G++ C+   C  G++     K C
Sbjct: 533 ECLQNGRICNNGR-CINTDGSFHCV---CNAGFHVTRDGKNC 570

 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 38/94 (40%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C+ GF       C DI+ECA +  P  C ++CVNTYGS+ C CP G+ L      C D D
Sbjct: 2192 CEEGFEPGPMMTCEDINECAQN--PLLCAFRCVNTYGSYECKCPAGYVLREDRRMCKDED 2249

Query: 200  ECRINSDICPNRKF-CINTPGNYSCIEPKCPDGY 298
            EC      C  ++  C N  G Y CI   C  GY
Sbjct: 2250 ECEEGKHDCAEKQMECKNLIGTYLCI---CGPGY 2280

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 39/102 (38%), Positives = 52/102 (50%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  G+I  G + C D+DEC+      S    C NT GS+ CLC  G+T       C D+D
Sbjct: 1350 CSPGWIGDGIK-CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLD 1406

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
            EC  N ++C N + C+N PG Y C   +C  G+      KAC
Sbjct: 1407 ECSENLNLCGNGQ-CLNAPGGYRC---ECDMGFVPSADGKAC 1444

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DIDEC     PG CQ  +C+NT+GSF C CP G+ L   T  C DV+EC       P   
Sbjct: 1606 DIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT- 1662

Query: 239  FCINTPGNYSCIEPKCPDGYN--------FDFRLKACLSNCTDKSPKC 358
             C NT GNY+CI   CP  Y          D R   C  N    +  C
Sbjct: 1663 -CYNTVGNYTCI---CPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRG-CIDIDECATDVKP-GSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C  G++   DR  C D DEC          Q +C N  G++ C+C PG+   P    C+D
Sbjct: 2232 CPAGYVLREDRRMCKDEDECEEGKHDCAEKQMECKNLIGTYLCICGPGYQRRPDGEGCVD 2291

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
             +EC+    IC N + C+NT G+Y+C   +C DG+        CL N
Sbjct: 2292 ENECQTKPGICENGR-CLNTRGSYTC---ECNDGFTASPNQDECLDN 2334

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 45/118 (38%), Positives = 60/118 (50%), Gaps = 4/118 (3%)
 Frame = +2

Query: 17   ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            +C  GF  + D+  C+DI+EC  D         C NT GSF+C C  GF L      CID
Sbjct: 1875 LCHTGFKTNADQTMCLDINECERDACGNGT---CRNTIGSFNCRCNHGFIL-SHNNDCID 1930

Query: 194  VDECRI-NSDICPNRKFCINTPGNYSCIEPKCPDGYNF--DFRLKACLSNCTDKSPKC 358
            VDEC   N ++C N + CINT G++ C   +C +GY    D R    ++ C     KC
Sbjct: 1931 VDECATGNGNLCRNGQ-CINTVGSFQC---QCNEGYEVAPDGRTCVDINECLLDPRKC 1984

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 4/134 (2%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DI+ECA D  P  C    C N  G++ C+C  G+ +      C+D++EC +NS +C N +
Sbjct: 723  DINECALD--PDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ 780

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLT---QASRIQYVVVQMTGS 409
             C NTPG++ C    CP G+ +   LK C      +S  C+    + S   ++    + S
Sbjct: 781  -CRNTPGSFVC---TCPKGFIYKPELKTCEDIDECESSPCINGVCKNSPGSFICECSSES 836

Query: 410  MAQPVEVRVINTMK 451
               P +   I T+K
Sbjct: 837  TLDPTKTICIETIK 850

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 2/120 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            +C  GF+ S D + C+D++EC  D+ P  C    C NT GSF C C  G++       C 
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC--DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
            D++EC I +  C     C NT G++ C    C  G+  D      L  C++ +  C   A
Sbjct: 1322 DINECEIGAHNCDRHAVCTNTAGSFKC---SCSPGWIGDGIKCTDLDECSNGTHMCSQHA 1378

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 34/88 (38%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
 Frame = +2

Query: 11  HEICKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
           H +C  GF  + D + C D+DEC+  ++       C+N  GSF C+C PGF L      C
Sbjct: 554 HCVCNAGFHVTRDGKNCEDMDECS--IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611

Query: 188 IDVDECRINSDICPNRKFCINTPGNYSC 271
            D++EC     IC N + C+NT G+Y C
Sbjct: 612 KDINECE-TLGICMNGR-CVNTDGSYRC 637

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 43/116 (37%), Positives = 57/116 (49%), Gaps = 3/116 (2%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C +GF+ S D + C DIDEC+    P  C +  C N  G F C C  G+ L      C D
Sbjct: 1431 CDMGFVPSADGKACEDIDECSL---PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD 1487

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD-KSPKC 358
            V+EC ++   C +   C+NTPG+Y+C    CP     DF L      C D +S  C
Sbjct: 1488 VNEC-LDPTTCISGN-CVNTPGSYTC---DCPP----DFELNPTRVGCVDTRSGNC 1534

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 2/129 (1%)
 Frame = +2

Query: 29   GFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECR 208
            GF+ +G     DIDEC   +       +CVN  GS+HC+C  G+T       C+D++EC 
Sbjct: 2395 GFMTNG----ADIDECKV-IHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNEC- 2448

Query: 209  INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ 382
             N    P    C NT G+Y C    CP GY      ++C  L  C  K   C       Q
Sbjct: 2449 -NQAPKPCNFICKNTEGSYQC---SCPKGYILQEDGRSCKDLDECATKQHNC-------Q 2497

Query: 383  YVVVQMTGS 409
            ++ V   GS
Sbjct: 2498 FLCVNTIGS 2506

 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 35/91 (38%), Positives = 44/91 (48%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            CID +EC +D+     +  C NT GSF C C  GF+L P    C DVDEC  N      +
Sbjct: 2522 CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDPTGASCEDVDECEGNHRC---Q 2578

Query: 236  KFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
              C N  G Y C    CP GY   ++   C+
Sbjct: 2579 HGCQNIIGGYRC---SCPQGYLQHYQWNQCV 2606

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            C D+DEC  + +   CQ+ C N  G + C CP G+  + +  +C+D +EC +++ IC   
Sbjct: 2565 CEDVDECEGNHR---CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGA 2620

Query: 236  KFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
              C NT G+Y C+   CP G+ ++     C  ++ C      C
Sbjct: 2621 S-CHNTLGSYKCM---CPAGFQYEQFSGGCQDINECGSAQAPC 2659

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 36/87 (41%), Positives = 47/87 (54%), Gaps = 2/87 (2%)
 Frame = +2

Query: 17  ICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           IC  G+ + S  + C+DI+EC  +     C   QC NT GSF C CP GF   P+   C 
Sbjct: 749 ICNSGYEVDSTGKNCVDINECVLNSL--LCDNGQCRNTPGSFVCTCPKGFIYKPELKTCE 806

Query: 191 DVDECRINSDICPNRKFCINTPGNYSC 271
           D+DEC   S  C N   C N+PG++ C
Sbjct: 807 DIDEC--ESSPCIN-GVCKNSPGSFIC 830

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            CK G+ ++    C D +EC     P  C + QC++T GSF+CLC  GF        C+D+
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEI--PNICSHGQCIDTVGSFYCLCHTGFKTNADQTMCLDI 1892

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
            +EC    D C N   C NT G+++C   +C  G+
Sbjct: 1893 NEC--ERDACGNGT-CRNTIGSFNC---RCNHGF 1920

 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 33/81 (40%), Positives = 46/81 (56%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
           C DIDEC  + +  +   +C+NT GSFHC+C  GF +      C D+DEC I  ++C N 
Sbjct: 528 CRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR-NMCLN- 584

Query: 236 KFCINTPGNYSCIEPKCPDGY 298
             CIN  G++ CI   C  G+
Sbjct: 585 GMCINEDGSFKCI---CKPGF 602

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
 Frame = +2

Query: 29   GFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDEC 205
            G I   D   +D+DEC    +P  C++ QC+NT GS+ C CP G+ L  +  +C+D DEC
Sbjct: 2116 GIIVGPDDSAVDMDECK---EPDVCKHGQCINTDGSYRCECPFGYIL--QGNECVDTDEC 2170

Query: 206  RINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
             + +  C N   C N  G + C    C +G+
Sbjct: 2171 SVGNP-CGNGT-CKNVIGGFEC---TCEEGF 2196

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 43/131 (32%), Positives = 59/131 (45%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            +CK G+   G   C D+DEC+ ++       QC+N  G + C C  GF        C D+
Sbjct: 1390 LCKEGYTGDGFT-CTDLDECSENLNLCG-NGQCLNAPGGYRCECDMGFVPSADGKACEDI 1447

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
            DEC +  +IC     C N PG + C   +C  GY  D        NCTD + +CL   + 
Sbjct: 1448 DECSL-PNICVFGT-CHNLPGLFRC---ECEIGYELD----RSGGNCTDVN-ECLDPTTC 1497

Query: 377  IQYVVVQMTGS 409
            I    V   GS
Sbjct: 1498 ISGNCVNTPGS 1508

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 25/48 (52%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
           C DIDEC+T   PG C   +C NT  S+ C CPPGF   P   +CIDV
Sbjct: 286 CEDIDECSTI--PGICDGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 59/229 (25%), Positives = 82/229 (35%), Gaps = 76/229 (33%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            IC  G+    D  GC+D +EC T  KPG C+  +C+NT GS+ C C  GFT  P   +C+
Sbjct: 2275 ICGPGYQRRPDGEGCVDENECQT--KPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2332

Query: 191  DVDE-----------CRINS-----------------------DICP------------- 229
            D  E           C+I S                       +ICP             
Sbjct: 2333 DNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPH 2392

Query: 230  NRKF---------------------CINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCT 340
             R F                     C+N  G+Y CI   C  GY  D    AC  L+ C 
Sbjct: 2393 GRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCI---CKTGYTPDITGTACVDLNECN 2449

Query: 341  DKSPKC--LTQASRIQYVVVQMTGSMAQP--VEVRVINTMKQKENNCQF 475
                 C  + + +   Y      G + Q      + ++    K++NCQF
Sbjct: 2450 QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF 2498

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
 Frame = +2

Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
           +C+ T GS+ C C  GF L  +  +CIDVDEC  N   C   + CINT G+Y+C   +C 
Sbjct: 464 RCIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNP--CAGGE-CINTQGSYTC---QCR 516

Query: 290 DGYNFDFRLKAC--LSNCTDKSPKC 358
            GY        C  +  C      C
Sbjct: 517 PGYQSTLTRTECRDIDECLQNGRIC 541

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 28/72 (38%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
 Frame = +2

Query: 20   CKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C+IG+      G C D++EC   + P +C    CVNT GS+ C CPP F L P  + C+D
Sbjct: 1472 CEIGYELDRSGGNCTDVNEC---LDPTTCISGNCVNTPGSYTCDCPPDFELNPTRVGCVD 1528

Query: 194  VDECRINSDICP 229
                    DI P
Sbjct: 1529 TRSGNCYLDIRP 1540

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  G+    D+ C DIDEC  +  P  C    C NT GSF CLCP GF+L     +C D
Sbjct: 1999 ICPPGYSLQNDK-CEDIDECVEE--PEICALGTCSNTEGSFKCLCPDGFSLSSTGRRCQD 2055

Query: 194  V 196
            +
Sbjct: 2056 L 2056

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  G+       C DIDEC  +V PG C+   CVN+ GSF C CP G TL      C+D
Sbjct: 895  ICGKGYSRIKGTQCEDIDEC--EVFPGVCKNGLCVNSKGSFKCQCPSGMTLDATGRICLD 952

Query: 194  V 196
            +
Sbjct: 953  I 953

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
 Frame = +2

Query: 41   SGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPP--------------GFTLYPKT 178
            +GD  C +  E    V   SC       +G+   LCPP              GF   P T
Sbjct: 1544 NGDTACSN--EIGVGVSKASCCCSLGKAWGTPCELCPPVNTSEYKILCPGGEGFRPNPIT 1601

Query: 179  MKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
            +   D+DEC+    +C   K CINT G++ C   +CP GY  +   + C
Sbjct: 1602 VILEDIDECQELPGLCQGGK-CINTFGSFQC---RCPTGYYLNEDTRVC 1646

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = +2

Query: 17   ICKIGFIWSG-DRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGF 160
            +C  GF +     GC DI+EC +   P  C Y C NT G + C CPPG+
Sbjct: 2632 MCPAGFQYEQFSGGCQDINECGSAQAP--CSYGCSNTEGGYLCACPPGY 2678

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
 Frame = +2

Query: 74   CATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECRINSDI 223
            C  ++   + + QC ++ G+             +C  G++    T +C D+DEC +   +
Sbjct: 862  CEININGATLKSQCCSSLGAAWGSPCTPCQVDPICGKGYSRIKGT-QCEDIDECEVFPGV 920

Query: 224  CPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            C N   C+N+ G++ C   +CP G   D   + CL
Sbjct: 921  CKN-GLCVNSKGSFKC---QCPSGMTLDATGRICL 951

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +2

Query: 17  ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           ICK GF  + D R C DI+EC T    G C   +CVNT GS+ C C PG  +      C+
Sbjct: 597 ICKPGFQLASDGRYCKDINECET---LGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653

Query: 191 D 193
           D
Sbjct: 654 D 654

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
 Frame = +2

Query: 101  CQYQCVNTYGSFHCLCP---PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
            C+   + +   F  LC    PGF +   T   +D+DECR    +C N   CIN  G++ C
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRC 1791

Query: 272  IEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
               +CP G+ ++ +L  C  +  C    P C   A  I
Sbjct: 1792 ---ECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECI 1825
>sp|Q08761|PROS_MOUSE Vitamin K-dependent protein S precursor
          Length = 675

 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 42/103 (40%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
 Frame = +2

Query: 20  CKIGFIWSGDRGCIDIDECATDVKP-GSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
           CK G  W GDR   D++EC       G C   C NT GS+HC C  GF + P    C D+
Sbjct: 145 CKPG--WQGDRCQYDVNECKDPSNVNGGCSQICDNTPGSYHCSCKRGFAMLPNKKDCKDL 202

Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
           DEC +   +C     C N PG++ C   +CPDGY +D   K+C
Sbjct: 203 DECALKPSVC-GTAVCKNIPGDFEC---ECPDGYRYDPSSKSC 241

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 48/140 (34%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
 Frame = +2

Query: 11  HEICKIGF-IWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMK 184
           H  CK GF +    + C D+DECA  +KP  C    C N  G F C CP G+   P +  
Sbjct: 183 HCSCKRGFAMLPNKKDCKDLDECA--LKPSVCGTAVCKNIPGDFECECPDGYRYDPSSKS 240

Query: 185 CIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFR--------LKACLSNCT 340
           C DVDEC  + ++C   + C+N PG YSC    C     F           +  CLS   
Sbjct: 241 CKDVDEC--SENMC--AQLCVNFPGGYSCY---CDGKKGFKLAQDQKSCEGIPVCLSLDL 293

Query: 341 DKSPKCLTQASRIQYVVVQM 400
           DK+ + L  A +   VV+ +
Sbjct: 294 DKNYELLYLAEQFAGVVLYL 313
>sp|Q9TV36|FBN1_PIG Fibrillin-1 precursor
          Length = 2871

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 43/105 (40%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            C+DIDEC+  +  G C+  C N+ GS+ C C PGF L P    C D+DEC  N +IC   
Sbjct: 1195 CVDIDECS--IMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGG 1252

Query: 236  KFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSPK-CLT 364
            + C N PG Y C+   C DG+     +K C+  N  D +P  CL+
Sbjct: 1253 Q-CTNIPGEYRCL---CYDGFMASEDMKTCVDVNECDLNPNICLS 1293

 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 42/95 (44%), Positives = 56/95 (58%), Gaps = 1/95 (1%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DI+EC   + P  C + +C NT GSF C C  GF L  +   CID+DECRI+ D+C  R 
Sbjct: 1028 DINECK--MIPNLCTHGKCRNTIGSFKCRCDSGFALDSEERNCIDIDECRISPDLC-GRG 1084

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
             C+NTPG++ C   KC +GY   F +   + NC D
Sbjct: 1085 QCVNTPGDFEC---KCDEGYESGFMM---MKNCMD 1113

 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 41/113 (36%), Positives = 55/113 (48%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  GFI S +  CID+DECAT         QC+NT GSF C C  G+ + P    C+D++
Sbjct: 1916 CNHGFILSHNNDCIDVDECATGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDIN 1975

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
            EC +    C     C N  G+Y CI   CP GY+        +  C ++   C
Sbjct: 1976 ECLLEPGKCAPGT-CQNLDGSYRCI---CPPGYSLQNDKCEDIDECVEEPEIC 2024

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 43/106 (40%), Positives = 59/106 (55%), Gaps = 3/106 (2%)
 Frame = +2

Query: 20   CKIGF-IWSGDRGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMK-CI 190
            C  GF + S +R CIDIDEC   + P  C + QCVNT G F C C  G+      MK C+
Sbjct: 1055 CDSGFALDSEERNCIDIDECR--ISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCM 1112

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            D+DEC+ +  +C     C+NT G+Y C   +CP G+     + AC+
Sbjct: 1113 DIDECQRDPLLC-RGGVCLNTEGSYRC---ECPSGHQMSPNISACI 1154

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 44/119 (36%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
 Frame = +2

Query: 11   HEICKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
            H ICK G+        C+D++EC    KP  C + C NT GS+ C CP G+ L      C
Sbjct: 2426 HCICKTGYTPDITGTACVDLNECNQAPKP--CNFICKNTEGSYQCSCPKGYILQEDGRSC 2483

Query: 188  IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN--CTDKSPKC 358
             D+DEC      C  +  C+NT G+++C   KCP G  F     AC+ N  CT     C
Sbjct: 2484 KDLDECATKQHNC--QFLCVNTIGSFAC---KCPPG--FTQHHTACIDNNECTSDINLC 2535

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 47/127 (37%), Positives = 68/127 (53%), Gaps = 8/127 (6%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C  G+  + D R C+DI+EC   ++PG C    C N  GS+ C+CPPG++L  +  KC D
Sbjct: 1958 CNEGYEVAPDGRTCVDINECL--LEPGKCAPGTCQNLDGSYRCICPPGYSL--QNDKCED 2013

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC----LSNCTDK--SPK 355
            +DEC    +IC     C NT G++ C+   CPDG++     + C    +S C  K    K
Sbjct: 2014 IDECVEEPEICALGT-CSNTEGSFKCL---CPDGFSLSSTGRRCQDLRMSYCYAKFEGGK 2069

Query: 356  CLTQASR 376
            C +  SR
Sbjct: 2070 CSSPKSR 2076

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 41/95 (43%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
 Frame = +2

Query: 20  CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
           C+ GFI +   G C D+DEC     PG CQ   C+NT GSF C CP G      + KC D
Sbjct: 231 CRRGFIPNIRTGACQDVDEC--QAIPGLCQGGNCINTVGSFECKCPAGHKFNEVSQKCED 288

Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
           +DEC     IC   + C NT  +Y C   KCP G+
Sbjct: 289 IDECSTIPGICDGGE-CTNTVSSYFC---KCPPGF 319

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 37/83 (44%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
 Frame = +2

Query: 59   IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            +DIDEC     PG C+   C+N  GSF C CP GF    K + C D+DEC+ N  +C   
Sbjct: 1765 VDIDECREI--PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRN 1821

Query: 236  KFCINTPGNYSCIEPKCPDGYNF 304
              CINT G+Y C    C  GY F
Sbjct: 1822 AECINTAGSYRC---DCKPGYRF 1841

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DIDEC     PG CQ  +C+NT+GSF C CP G+ L   T  C DV+EC       P   
Sbjct: 1606 DIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT- 1662

Query: 239  FCINTPGNYSCIEPKCPDGYN--------FDFRLKACLSNCTDKSPKC 358
             C NT GNY+CI   CP  Y          D R   C  N    +  C
Sbjct: 1663 -CYNTVGNYTCI---CPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 38/94 (40%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C+ GF       C DI+ECA +  P  C ++CVNTYGS+ C CP G+ L      C D D
Sbjct: 2192 CEEGFEPGPMMTCEDINECAQN--PLLCAFRCVNTYGSYECKCPTGYVLREDRRMCKDED 2249

Query: 200  ECRINSDICPNRKF-CINTPGNYSCIEPKCPDGY 298
            EC      C  ++  C N  G Y CI   C  GY
Sbjct: 2250 ECEEGKHDCAEKQMECKNLIGMYICI---CGPGY 2280

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 45/118 (38%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
 Frame = +2

Query: 17   ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            +C  GF  + D+  C+DI+EC  D         C NT GSF+C C  GF L      CID
Sbjct: 1875 LCHTGFKTNADQTMCLDINECERDACGNGT---CRNTIGSFNCRCNHGFIL-SHNNDCID 1930

Query: 194  VDECRI-NSDICPNRKFCINTPGNYSCIEPKCPDGYNF--DFRLKACLSNCTDKSPKC 358
            VDEC   N ++C N + CINT G++ C   +C +GY    D R    ++ C  +  KC
Sbjct: 1931 VDECATGNGNLCRNGQ-CINTVGSFQC---QCNEGYEVAPDGRTCVDINECLLEPGKC 1984

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 37/102 (36%), Positives = 51/102 (50%)
 Frame = +2

Query: 20  CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
           C  GF       CID+DEC  +   G    +C+N  GS+ C C PG+       +C D+D
Sbjct: 476 CNKGFQLDLRGECIDVDECEKNPCAGG---ECINNQGSYTCQCRPGYQSTLTRTECRDID 532

Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
           EC  N  IC N + CINT G++ C+   C  G++     K C
Sbjct: 533 ECLQNGRICNNGR-CINTDGSFHCV---CNAGFHVTRDGKNC 570

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 37/107 (34%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRG-CIDIDECATDVKP-GSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C  G++   DR  C D DEC          Q +C N  G + C+C PG+   P    C+D
Sbjct: 2232 CPTGYVLREDRRMCKDEDECEEGKHDCAEKQMECKNLIGMYICICGPGYQRRPDGEGCVD 2291

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
             +EC+    IC N + C+NT G+Y+C   +C DG+        CL N
Sbjct: 2292 ENECQTKPGICENGR-CLNTRGSYTC---ECNDGFTASPTQDECLDN 2334

 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 35/88 (39%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
 Frame = +2

Query: 11  HEICKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
           H +C  GF  + D + C D+DEC+  ++       C+N  GSF C+C PGF L      C
Sbjct: 554 HCVCNAGFHVTRDGKNCEDMDECS--IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611

Query: 188 IDVDECRINSDICPNRKFCINTPGNYSC 271
            D++EC   S IC N + C+NT G+Y C
Sbjct: 612 KDINECE-TSGICMNGR-CVNTDGSYRC 637

 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 2/120 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            +C  GF+ S D + C+D++EC  D+ P  C    C NT GSF C C  G++       C 
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC--DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
            D++EC I +  C     C NT G+++C    C  G+  D      L  C++ +  C   A
Sbjct: 1322 DINECEIGAHNCDRHAVCTNTAGSFNC---SCSPGWIGDGIKCTDLDECSNGTHMCSQHA 1378

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 4/134 (2%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DI+ECA D  P  C    C N  G++ C+C  G+ +      C+D++EC +NS +C N +
Sbjct: 723  DINECALD--PDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ 780

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLT---QASRIQYVVVQMTGS 409
             C NTPG++ C    CP G+ +   LK C      +S  C+    + S   ++    + S
Sbjct: 781  -CRNTPGSFVC---TCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSES 836

Query: 410  MAQPVEVRVINTMK 451
               P +   I T+K
Sbjct: 837  TLDPTKTICIETIK 850

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 30/73 (41%), Positives = 45/73 (61%), Gaps = 1/73 (1%)
 Frame = +2

Query: 50   RGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
            + C+DIDEC  D  P  C+   C+NT GS+ C CP G  + P    CID++EC +++ +C
Sbjct: 1109 KNCMDIDECQRD--PLLCRGGVCLNTEGSYRCECPSGHQMSPNISACIDINECELSAHLC 1166

Query: 227  PNRKFCINTPGNY 265
            P+ + C+N  G Y
Sbjct: 1167 PHGR-CVNLIGKY 1178

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQ-YQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C+ GF    D R C DIDEC  +  P  C   QC N  G + CLC  GF        C+D
Sbjct: 1223 CQPGFALMPDQRSCTDIDEC--EDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVD 1280

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
            V+EC +N +IC +   C NT G++ C    C  GY+     K   + CTD
Sbjct: 1281 VNECDLNPNICLSGT-CENTKGSFIC---HCDMGYSG----KKGKTGCTD 1322

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 40/113 (35%), Positives = 53/113 (46%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  G+I  G + C D+DEC+      S    C NT GS+ CLC  G+T       C D+D
Sbjct: 1350 CSPGWIGDGIK-CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCADLD 1406

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
            EC  N  +C N + C+  PG Y C        Y+  F   A   +C D S +C
Sbjct: 1407 ECSENVKLCGNVQ-CLYAPGGYHC-------EYDMGFVPSADRKSCVD-SDEC 1450

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 43/131 (32%), Positives = 59/131 (45%), Gaps = 2/131 (1%)
 Frame = +2

Query: 29   GFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECR 208
            GF+ +G     DIDEC   +       +C+N  GS+HC+C  G+T       C+D++EC 
Sbjct: 2395 GFMTNG----ADIDECKV-IHDVCRNGECINDRGSYHCICKTGYTPDITGTACVDLNEC- 2448

Query: 209  INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ 382
             N    P    C NT G+Y C    CP GY      ++C  L  C  K   C       Q
Sbjct: 2449 -NQAPKPCNFICKNTEGSYQC---SCPKGYILQEDGRSCKDLDECATKQHNC-------Q 2497

Query: 383  YVVVQMTGSMA 415
            ++ V   GS A
Sbjct: 2498 FLCVNTIGSFA 2508

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
 Frame = +2

Query: 20   CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C+ GF +      C D+DEC  + +   CQ+ C N  G + C CP G+  + +  +C+D 
Sbjct: 2552 CQRGFSLDQSGASCEDVDECEGNHR---CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
            +EC +++ IC     C NT G+Y C+   CP G+ ++     C  ++ C      C
Sbjct: 2609 NEC-LSAHICGGAS-CHNTLGSYKCM---CPAGFQYEQFSGGCQDINECGSSQAPC 2659

 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 42/114 (36%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
 Frame = +2

Query: 26   IGFIWSGDR-GCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            +GF+ S DR  C+D DEC+    P  C +  C N  G F C C  G+ L      C DV+
Sbjct: 1433 MGFVPSADRKSCVDSDECSL---PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVN 1489

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD-KSPKC 358
            EC +    C +   C+NTPG+Y+C+   CP     DF L      C D +S  C
Sbjct: 1490 EC-LEPPTCISGN-CVNTPGSYTCV---CPP----DFELNPTRVGCVDTRSGNC 1534

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            CK G+ ++    C D +EC     P  C + QC++T GSF+CLC  GF        C+D+
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEI--PNICSHGQCIDTVGSFYCLCHTGFKTNADQTMCLDI 1892

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
            +EC    D C N   C NT G+++C   +C  G+
Sbjct: 1893 NEC--ERDACGNGT-CRNTIGSFNC---RCNHGF 1920

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
 Frame = +2

Query: 17  ICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           IC  G+ + S  + C+DI+EC  +     C   QC NT GSF C CP GF   P    C 
Sbjct: 749 ICNSGYEVDSTGKNCVDINECVLNSL--LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806

Query: 191 DVDECRINSDICPNRKFCINTPGNYSC 271
           D+DEC   S  C N   C N+PG++ C
Sbjct: 807 DIDEC--ESSPCIN-GVCKNSPGSFIC 830

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 34/91 (37%), Positives = 43/91 (47%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            CID +EC +D+     +  C NT GSF C C  GF+L      C DVDEC  N      +
Sbjct: 2522 CIDNNECTSDINLCGAKGICQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRC---Q 2578

Query: 236  KFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
              C N  G Y C    CP GY   ++   C+
Sbjct: 2579 HGCQNIIGGYRC---SCPQGYLQHYQWNQCV 2606

 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 33/81 (40%), Positives = 46/81 (56%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
           C DIDEC  + +  +   +C+NT GSFHC+C  GF +      C D+DEC I  ++C N 
Sbjct: 528 CRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR-NMCLN- 584

Query: 236 KFCINTPGNYSCIEPKCPDGY 298
             CIN  G++ CI   C  G+
Sbjct: 585 GMCINEDGSFKCI---CKPGF 602

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 49/169 (28%), Positives = 75/169 (44%), Gaps = 8/169 (4%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPN 232
            CIDI+EC  ++    C + +CVN  G +     PG+   P  + C+D+DEC I +  C  
Sbjct: 1153 CIDINEC--ELSAHLCPHGRCVNLIGKYQRARNPGYHSTPDRLFCVDIDECSIMNGGC-- 1208

Query: 233  RKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC-LTQASRI--QYVVVQ 397
              FC N+ G+Y C    C  G+      ++C  +  C D    C   Q + I  +Y  + 
Sbjct: 1209 ETFCTNSEGSYEC---SCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLC 1265

Query: 398  MTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPI--TYESLQGSII 538
              G MA           +  +      E D+ PNI +  T E+ +GS I
Sbjct: 1266 YDGFMAS----------EDMKTCVDVNECDLNPNICLSGTCENTKGSFI 1304

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
 Frame = +2

Query: 29   GFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDEC 205
            G I   D   +D+DEC    +P  C++ QC+NT GS+ C CP G+ L  +  +C+D DEC
Sbjct: 2116 GIIVGPDDSAVDMDECK---EPDVCKHGQCINTDGSYRCECPFGYIL--EGNECVDTDEC 2170

Query: 206  RINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
             + +  C N   C N  G + C    C +G+
Sbjct: 2171 SVGNP-CGNGT-CKNVIGGFEC---TCEEGF 2196

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 44/131 (33%), Positives = 59/131 (45%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            +CK G+   G   C D+DEC+ +VK      QC+   G +HC    GF        C+D 
Sbjct: 1390 LCKEGYTGDGFT-CADLDECSENVKLCG-NVQCLYAPGGYHCEYDMGFVPSADRKSCVDS 1447

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
            DEC +  +IC     C N PG + C   +C  GY  D        NCTD + +CL   + 
Sbjct: 1448 DECSL-PNICVFGT-CHNLPGLFRC---ECEIGYELD----RSGGNCTDVN-ECLEPPTC 1497

Query: 377  IQYVVVQMTGS 409
            I    V   GS
Sbjct: 1498 ISGNCVNTPGS 1508

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 27/72 (37%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
 Frame = +2

Query: 20   CKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C+IG+      G C D++EC   ++P +C    CVNT GS+ C+CPP F L P  + C+D
Sbjct: 1472 CEIGYELDRSGGNCTDVNEC---LEPPTCISGNCVNTPGSYTCVCPPDFELNPTRVGCVD 1528

Query: 194  VDECRINSDICP 229
                    D+ P
Sbjct: 1529 TRSGNCYLDVRP 1540

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 25/48 (52%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
           C DIDEC+T   PG C   +C NT  S+ C CPPGF   P   +CIDV
Sbjct: 286 CEDIDECSTI--PGICDGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 60/229 (26%), Positives = 82/229 (35%), Gaps = 76/229 (33%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            IC  G+    D  GC+D +EC T  KPG C+  +C+NT GS+ C C  GFT  P   +C+
Sbjct: 2275 ICGPGYQRRPDGEGCVDENECQT--KPGICENGRCLNTRGSYTCECNDGFTASPTQDECL 2332

Query: 191  DVDE-----------CRINS-----------------------DICP------------- 229
            D  E           C+I S                       +ICP             
Sbjct: 2333 DNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPH 2392

Query: 230  NRKF---------------------CINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCT 340
             R F                     CIN  G+Y CI   C  GY  D    AC  L+ C 
Sbjct: 2393 GRGFMTNGADIDECKVIHDVCRNGECINDRGSYHCI---CKTGYTPDITGTACVDLNECN 2449

Query: 341  DKSPKC--LTQASRIQYVVVQMTGSMAQP--VEVRVINTMKQKENNCQF 475
                 C  + + +   Y      G + Q      + ++    K++NCQF
Sbjct: 2450 QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF 2498

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  G+    D+ C DIDEC  +  P  C    C NT GSF CLCP GF+L     +C D
Sbjct: 1999 ICPPGYSLQNDK-CEDIDECVEE--PEICALGTCSNTEGSFKCLCPDGFSLSSTGRRCQD 2055

Query: 194  V 196
            +
Sbjct: 2056 L 2056

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
 Frame = +2

Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
           +C+ T GS+ C C  GF L  +  +CIDVDEC  N   C   + CIN  G+Y+C   +C 
Sbjct: 464 RCIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNP--CAGGE-CINNQGSYTC---QCR 516

Query: 290 DGYNFDFRLKAC--LSNCTDKSPKC 358
            GY        C  +  C      C
Sbjct: 517 PGYQSTLTRTECRDIDECLQNGRIC 541

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  G+       C DIDEC  +V PG C+   CVN+ GSF C CP G TL      C+D
Sbjct: 895  ICGKGYSRIKGTQCEDIDEC--EVFPGVCKNGLCVNSKGSFKCQCPNGMTLDATGRICLD 952

Query: 194  V 196
            +
Sbjct: 953  I 953

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +2

Query: 17  ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           ICK GF  + D R C DI+EC T    G C   +CVNT GS+ C C PG  +      C+
Sbjct: 597 ICKPGFQLASDGRYCKDINECETS---GICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653

Query: 191 D 193
           D
Sbjct: 654 D 654

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = +2

Query: 17   ICKIGFIWSG-DRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGF 160
            +C  GF +     GC DI+EC +   P  C Y C NT G + C CPPG+
Sbjct: 2632 MCPAGFQYEQFSGGCQDINECGSSQAP--CSYGCSNTEGGYLCGCPPGY 2678

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 10/95 (10%)
 Frame = +2

Query: 74   CATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECRINSDI 223
            C  ++   + + QC ++ G+             +C  G++    T +C D+DEC +   +
Sbjct: 862  CEININGATLKSQCCSSLGAAWGSPCTPCQVDPICGKGYSRIKGT-QCEDIDECEVFPGV 920

Query: 224  CPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            C N   C+N+ G++ C   +CP+G   D   + CL
Sbjct: 921  CKN-GLCVNSKGSFKC---QCPNGMTLDATGRICL 951

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 29/76 (38%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
 Frame = +2

Query: 110  QC--VNTYGSFHCLCP--PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIE 277
            QC  VNT   +  LCP   GF   P T+   D+DEC+    +C   K CINT G++ C  
Sbjct: 1576 QCPPVNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-CINTFGSFQC-- 1631

Query: 278  PKCPDGYNFDFRLKAC 325
             +CP GY  +   + C
Sbjct: 1632 -RCPTGYYLNEDTRVC 1646

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
 Frame = +2

Query: 101  CQYQCVNTYGSFHCLCP---PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
            C+   + +   F  LC    PGF +   T   +D+DECR    +C N   CIN  G++ C
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRC 1791

Query: 272  IEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
               +CP G+ ++ +L  C  +  C    P C   A  I
Sbjct: 1792 ---ECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECI 1825
>sp|Q61554|FBN1_MOUSE Fibrillin-1 precursor
          Length = 2871

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 46/118 (38%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
 Frame = +2

Query: 20   CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  G+  + DR  C+DIDEC+  +  G C+  C N+ GS+ C C PGF L P    C D+
Sbjct: 1182 CNPGYHPTHDRLFCVDIDECS--IMNGGCETFCTNSDGSYECSCQPGFALMPDQRSCTDI 1239

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSPK-CLT 364
            D+C  N +IC   + C N PG Y C+   C DG+     +K C+  N  D +P  CL+
Sbjct: 1240 DQCEDNPNICDGGQ-CTNIPGEYRCL---CYDGFMASEDMKTCVDVNECDLNPNICLS 1293

 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 42/113 (37%), Positives = 56/113 (49%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  GFI S +  CID+DECAT         QCVNT GSF C C  G+ + P    C+D++
Sbjct: 1916 CNHGFILSHNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDIN 1975

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
            EC ++   C     C N  G+Y CI   CP GY+        +  C ++   C
Sbjct: 1976 ECVLDPGKCAPGT-CQNLDGSYRCI---CPPGYSLQNDKCEDIDECVEEPEIC 2024

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 41/95 (43%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DI+EC   + P  C + +C NT GSF C C  GF L  +   C D+DECRI+ D+C  R 
Sbjct: 1028 DINECK--MIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC-GRG 1084

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
             C+NTPG++ C   KC +GY   F +   + NC D
Sbjct: 1085 QCVNTPGDFEC---KCDEGYESGFMM---MKNCMD 1113

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 51/163 (31%), Positives = 75/163 (46%), Gaps = 5/163 (3%)
 Frame = +2

Query: 50   RGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
            + C+DIDEC  D  P  C+   C NT G++ C CPPG  L P    CID++EC +++++C
Sbjct: 1109 KNCMDIDECQRD--PLLCRGGICHNTEGTYRCECPPGHQLSPNISACIDINECELSANLC 1166

Query: 227  PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI--QYVVV 394
            P+ + C+N  G Y C    C  GY+       C  +  C+  +  C T  +     Y   
Sbjct: 1167 PHGR-CVNLIGKYQC---ACNPGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECS 1222

Query: 395  QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
               G    P + R    + Q E+N    +     NIP  Y  L
Sbjct: 1223 CQPGFALMP-DQRSCTDIDQCEDNPNICDGGQCTNIPGEYRCL 1264

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 47/127 (37%), Positives = 68/127 (53%), Gaps = 8/127 (6%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C  G+  + D R C+DI+EC  D  PG C    C N  GS+ C+CPPG++L  +  KC D
Sbjct: 1958 CNEGYEVAPDGRTCVDINECVLD--PGKCAPGTCQNLDGSYRCICPPGYSL--QNDKCED 2013

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC----LSNCTDK--SPK 355
            +DEC    +IC     C NT G++ C+   CP+G+++    + C    +S C  K    K
Sbjct: 2014 IDECVEEPEICALGT-CSNTEGSFKCL---CPEGFSWSSSGRRCQDLRMSYCYAKFEGGK 2069

Query: 356  CLTQASR 376
            C +  SR
Sbjct: 2070 CSSPKSR 2076

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 44/119 (36%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
 Frame = +2

Query: 11   HEICKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
            H ICK G+        C+D++EC    KP  C + C NT GS+ C CP G+ L      C
Sbjct: 2426 HCICKTGYTPDITGTSCVDLNECNQAPKP--CNFICKNTEGSYQCSCPNGYILQEDGRSC 2483

Query: 188  IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN--CTDKSPKC 358
             D+DEC      C  +  C+NT G ++C   KCP G  F     AC+ N  CT     C
Sbjct: 2484 KDLDECATKQHNC--QFLCVNTIGGFTC---KCPPG--FTQHHTACIDNNECTSDINLC 2535

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 40/95 (42%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
 Frame = +2

Query: 20  CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
           C+ GFI +   G C D+DEC     PG CQ   C+NT GSF C CP G      + KC D
Sbjct: 231 CRRGFIPNIRTGACQDVDEC--QAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQKCED 288

Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
           +DEC     +C   + C NT  +Y C   KCP G+
Sbjct: 289 IDECSTIPGVCDGGE-CTNTVSSYFC---KCPPGF 319

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 39/107 (36%), Positives = 56/107 (52%), Gaps = 2/107 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRG-CIDIDECATDVKPGS-CQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C +G++   DR  C D DECA      +  Q +C N  G++ C+C PG+   P    CID
Sbjct: 2232 CPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCID 2291

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
             +EC+    IC N + C+NT G+Y+C   +C DG+        CL N
Sbjct: 2292 ENECQTKPGICENGR-CLNTLGSYTC---ECNDGFTASPTQDECLDN 2334

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 42/106 (39%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
 Frame = +2

Query: 20   CKIGF-IWSGDRGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMK-CI 190
            C  GF + S +R C DIDEC   + P  C + QCVNT G F C C  G+      MK C+
Sbjct: 1055 CDSGFALDSEERNCTDIDECR--ISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCM 1112

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            D+DEC+ +  +C     C NT G Y C   +CP G+     + AC+
Sbjct: 1113 DIDECQRDPLLC-RGGICHNTEGTYRC---ECPPGHQLSPNISACI 1154

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 39/102 (38%), Positives = 52/102 (50%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C  G+I  G + C D+DEC+      S    C NT GS+ CLC  G+T       C D+D
Sbjct: 1350 CSPGWIGDGIK-CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGYT--GDGFTCTDLD 1406

Query: 200  ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
            EC  N ++C N + C+N PG Y C   +C  G+      KAC
Sbjct: 1407 ECSENLNLCGNGQ-CLNAPGGYRC---ECDMGFVPSADGKAC 1444

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DIDEC     PG CQ  +C+NT+GSF C CP G+ L   T  C DV+EC       P   
Sbjct: 1606 DIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT- 1662

Query: 239  FCINTPGNYSCIEPKCPDGYN--------FDFRLKACLSNCTDKSPKC 358
             C NT GNY+CI   CP  Y          D R   C  N    +  C
Sbjct: 1663 -CYNTVGNYTCI---CPPDYMQVNGGNNCMDMRRSICYRNYYADNQTC 1706

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 38/94 (40%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
            C+ GF       C DI+ECA +  P  C ++CVNTYGS+ C CP G+ L      C D D
Sbjct: 2192 CEEGFEPGPMMTCEDINECAQN--PLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDED 2249

Query: 200  ECRINSDICPNRKF-CINTPGNYSCIEPKCPDGY 298
            EC      C  ++  C N  G Y CI   C  GY
Sbjct: 2250 ECAEGKHDCTEKQMECKNLIGTYMCI---CGPGY 2280

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 37/89 (41%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
 Frame = +2

Query: 11  HEICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMK 184
           H +C  GF + S  + C D+DEC T   P  C    C+N  GSF C+C PGF L      
Sbjct: 554 HCVCNAGFHVSSEGKNCEDMDECRT---PNMCPNGMCINEDGSFKCICKPGFQLASDGRY 610

Query: 185 CIDVDECRINSDICPNRKFCINTPGNYSC 271
           C D++EC     IC N + C+NT G+Y C
Sbjct: 611 CKDINECE-TPGICMNGR-CVNTDGSYRC 637

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 36/81 (44%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 59   IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            +DIDEC     PG C+   C+N  GSF C CP GF    K + C D+DEC+ N  +C   
Sbjct: 1765 VDIDECREI--PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCLRN 1821

Query: 236  KFCINTPGNYSCIEPKCPDGY 298
              CINT G+Y C    C  GY
Sbjct: 1822 AECINTAGSYRC---DCKPGY 1839

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 44/118 (37%), Positives = 60/118 (50%), Gaps = 4/118 (3%)
 Frame = +2

Query: 17   ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            +C  GF  + D+  C+DI+EC  D         C NT GSF+C C  GF L      CID
Sbjct: 1875 LCHTGFKTNEDQTMCLDINECERDACGNGT---CRNTIGSFNCRCNHGFIL-SHNNDCID 1930

Query: 194  VDECRI-NSDICPNRKFCINTPGNYSCIEPKCPDGYNF--DFRLKACLSNCTDKSPKC 358
            VDEC   N ++C N + C+NT G++ C   +C +GY    D R    ++ C     KC
Sbjct: 1931 VDECATGNGNLCRNGQ-CVNTVGSFQC---RCNEGYEVAPDGRTCVDINECVLDPGKC 1984

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 2/120 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            +C  GF+ S D + C+D++EC  D+ P  C    C NT GSF C C  G++       C 
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC--DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
            D++EC I +  C     C NT G++ C    C  G+  D      L  C++ +  C   A
Sbjct: 1322 DINECEIGAHNCGRHAVCTNTAGSFKC---SCSPGWIGDGIKCTDLDECSNGTHMCSQHA 1378

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 36/102 (35%), Positives = 50/102 (49%)
 Frame = +2

Query: 20  CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
           C  GF       CID+DEC  +   G    +C+N  GS+ C C  G+       +C D+D
Sbjct: 476 CNKGFQLDIRGECIDVDECEKNPCTGG---ECINNQGSYTCHCRAGYQSTLTRTECRDID 532

Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
           EC  N  IC N + CINT G++ C+   C  G++     K C
Sbjct: 533 ECLQNGRICNNGR-CINTDGSFHCV---CNAGFHVSSEGKNC 570

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 34/81 (41%), Positives = 48/81 (59%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
           C DIDEC  + +  +   +C+NT GSFHC+C  GF +  +   C D+DECR   ++CPN 
Sbjct: 528 CRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVSSEGKNCEDMDECR-TPNMCPN- 584

Query: 236 KFCINTPGNYSCIEPKCPDGY 298
             CIN  G++ CI   C  G+
Sbjct: 585 GMCINEDGSFKCI---CKPGF 602

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 1/101 (0%)
 Frame = +2

Query: 62   DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
            DI+ECA D  P  C    C N  G++ C+C  G+ +      C+D++EC +NS +C N +
Sbjct: 723  DINECALD--PDICPNGICENLRGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQ 780

Query: 239  FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCL 361
             C NTPG++ C    CP G+ +   LK C      +S  C+
Sbjct: 781  -CRNTPGSFVC---TCPKGFVYKPDLKTCEDIDECESSPCI 817

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 34/116 (29%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
 Frame = +2

Query: 20   CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C+ GF +      C D+DEC  + +   CQ+ C N  G + C CP G+  + +  +C+D 
Sbjct: 2552 CQRGFSLDQSGASCEDVDECEGNHR---CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
            +EC +++ +C     C NT G+Y C+   CP G+ ++     C  ++ C      C
Sbjct: 2609 NEC-LSAHVCGGAS-CHNTLGSYKCM---CPAGFQYEQFSGGCQDINECGSSQAPC 2659

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 38/112 (33%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
 Frame = +2

Query: 29   GFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECR 208
            GF+ +G     D+DEC   +       +CVN  GS+HC+C  G+T       C+D++EC 
Sbjct: 2395 GFMTNG----ADVDECKV-IHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC- 2448

Query: 209  INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
             N    P    C NT G+Y C    CP+GY      ++C  L  C  K   C
Sbjct: 2449 -NQAPKPCNFICKNTEGSYQC---SCPNGYILQEDGRSCKDLDECATKQHNC 2496

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 42/116 (36%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C +GF+ S D + C DIDEC+    P  C +  C N  G F C C  G+ L      C D
Sbjct: 1431 CDMGFVPSADGKACEDIDECSL---PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD 1487

Query: 194  VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD-KSPKC 358
            V+EC ++   C +   C+NTPG+Y+C    C      DF L      C D +S  C
Sbjct: 1488 VNEC-LDPTTCISGN-CVNTPGSYTC---DCSP----DFELNPTRVGCVDTRSGNC 1534

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 34/91 (37%), Positives = 43/91 (47%)
 Frame = +2

Query: 56   CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
            CID +EC +D+     +  C NT GSF C C  GF+L      C DVDEC  N      +
Sbjct: 2522 CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRC---Q 2578

Query: 236  KFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
              C N  G Y C    CP GY   ++   C+
Sbjct: 2579 HGCQNIIGGYRC---SCPQGYLQHYQWNQCV 2606

 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
 Frame = +2

Query: 20   CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            CK G+  +    C D +EC     P  C + QC++T GSF+CLC  GF        C+D+
Sbjct: 1835 CKPGYRLTSTGQCNDRNECQEI--PNICSHGQCIDTVGSFYCLCHTGFKTNEDQTMCLDI 1892

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
            +EC    D C N   C NT G+++C   +C  G+
Sbjct: 1893 NEC--ERDACGNGT-CRNTIGSFNC---RCNHGF 1920

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 35/87 (40%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
 Frame = +2

Query: 17  ICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           IC  G+ +    + C+DI+EC  +     C   QC NT GSF C CP GF   P    C 
Sbjct: 749 ICNSGYEVDITGKNCVDINECVLNSL--LCDNGQCRNTPGSFVCTCPKGFVYKPDLKTCE 806

Query: 191 DVDECRINSDICPNRKFCINTPGNYSC 271
           D+DEC   S  C N   C N+PG++ C
Sbjct: 807 DIDEC--ESSPCIN-GVCKNSPGSFIC 830

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 35/98 (35%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
 Frame = +2

Query: 14   EICKIG--FIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMK 184
            +IC  G   I   D   +D+DEC    +P  C++ QC+NT GS+ C CP G+ L  +  +
Sbjct: 2109 QICPFGSGIIVGPDDSAVDMDECK---EPDVCRHGQCINTDGSYRCECPFGYIL--EGNE 2163

Query: 185  CIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
            C+D DEC + +  C N   C N  G + C    C +G+
Sbjct: 2164 CVDTDECSVGNP-CGNGT-CKNVIGGFEC---TCEEGF 2196

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 43/131 (32%), Positives = 59/131 (45%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            +CK G+   G   C D+DEC+ ++       QC+N  G + C C  GF        C D+
Sbjct: 1390 LCKDGYTGDGFT-CTDLDECSENLNLCG-NGQCLNAPGGYRCECDMGFVPSADGKACEDI 1447

Query: 197  DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
            DEC +  +IC     C N PG + C   +C  GY  D        NCTD + +CL   + 
Sbjct: 1448 DECSL-PNICVFGT-CHNLPGLFRC---ECEIGYELD----RSGGNCTDVN-ECLDPTTC 1497

Query: 377  IQYVVVQMTGS 409
            I    V   GS
Sbjct: 1498 ISGNCVNTPGS 1508

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
 Frame = +2

Query: 20   CKIGFIWSGDR-GCIDIDECATDVKPGSC--QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            C +GF ++     C DIDEC        C    +C+NT GS+ C C PG+ L   T +C 
Sbjct: 1793 CPVGFFYNDKLLVCEDIDECQNGPV---CLRNAECINTAGSYRCDCKPGYRL-TSTGQCN 1848

Query: 191  DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            D +EC+   +IC + + CI+T G++ C+   C  G+  +     CL
Sbjct: 1849 DRNECQEIPNICSHGQ-CIDTVGSFYCL---CHTGFKTNEDQTMCL 1890

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 31/74 (41%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
 Frame = +2

Query: 17   ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
            IC  G+    D  GCID +EC T  KPG C+  +C+NT GS+ C C  GFT  P   +C+
Sbjct: 2275 ICGPGYQRRPDGEGCIDENECQT--KPGICENGRCLNTLGSYTCECNDGFTASPTQDECL 2332

Query: 191  DVDECRINSDICPN 232
            D  E    S++  N
Sbjct: 2333 DNREGYCFSEVFEN 2346

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 24/48 (50%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
 Frame = +2

Query: 56  CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
           C DIDEC+T   PG C   +C NT  S+ C CPPGF   P   +C+DV
Sbjct: 286 CEDIDECSTI--PGVCDGGECTNTVSSYFCKCPPGFYTSPDGTRCVDV 331

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 28/61 (45%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
 Frame = +2

Query: 17  ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
           ICK GF  + D R C DI+EC T   PG C   +CVNT GS+ C C PG  +      C+
Sbjct: 597 ICKPGFQLASDGRYCKDINECET---PGICMNGRCVNTDGSYRCECFPGLAVGLDGRWCV 653

Query: 191 D 193
           D
Sbjct: 654 D 654

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
 Frame = +2

Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
           +C+ T GS+ C C  GF L  +  +CIDVDEC  N   C   + CIN  G+Y+C    C 
Sbjct: 464 RCIPTPGSYRCECNKGFQLDIRG-ECIDVDECEKNP--CTGGE-CINNQGSYTC---HCR 516

Query: 290 DGYNFDFRLKAC--LSNCTDKSPKC 358
            GY        C  +  C      C
Sbjct: 517 AGYQSTLTRTECRDIDECLQNGRIC 541

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  GF       C DI+EC  +V PG C+   CVN+ GSF C CP G TL      C+D
Sbjct: 895  ICGKGFSRIKGTQCEDINEC--EVFPGVCKNGLCVNSRGSFKCECPNGMTLDATGRICLD 952

Query: 194  V 196
            +
Sbjct: 953  I 953

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
 Frame = +2

Query: 17   ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            IC  G+    D+ C DIDEC  +  P  C    C NT GSF CLCP GF+      +C D
Sbjct: 1999 ICPPGYSLQNDK-CEDIDECVEE--PEICALGTCSNTEGSFKCLCPEGFSWSSSGRRCQD 2055

Query: 194  V 196
            +
Sbjct: 2056 L 2056

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 26/69 (37%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
 Frame = +2

Query: 20   CKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
            C+IG+      G C D++EC   + P +C    CVNT GS+ C C P F L P  + C+D
Sbjct: 1472 CEIGYELDRSGGNCTDVNEC---LDPTTCISGNCVNTPGSYTCDCSPDFELNPTRVGCVD 1528

Query: 194  V--DECRIN 214
                 C +N
Sbjct: 1529 TRSGNCYLN 1537

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
 Frame = +2

Query: 101  CQYQCVNTYGSFHCLCP---PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
            C+   + +   F  LC    PGF +   T   +D+DECR    +C N   CIN  G++ C
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRC 1791

Query: 272  IEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
               +CP G+ ++ +L  C  +  C    P CL  A  I
Sbjct: 1792 ---ECPVGFFYNDKLLVCEDIDEC-QNGPVCLRNAECI 1825

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = +2

Query: 17   ICKIGFIWSG-DRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGF 160
            +C  GF +     GC DI+EC +   P  C Y C NT G + C CPPG+
Sbjct: 2632 MCPAGFQYEQFSGGCQDINECGSSQAP--CSYGCSNTEGGYLCGCPPGY 2678

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
 Frame = +2

Query: 116  VNTYGSFHCLCP--PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
            VNT   +  LCP   GF   P T+   D+DEC+    +C   K CINT G++ C   +CP
Sbjct: 1580 VNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-CINTFGSFQC---RCP 1634

Query: 290  DGYNFDFRLKAC 325
             GY  +   + C
Sbjct: 1635 TGYYLNEDTRVC 1646

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 10/95 (10%)
 Frame = +2

Query: 74   CATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECRINSDI 223
            C  ++   + + +C ++ G+             +C  GF+    T +C D++EC +   +
Sbjct: 862  CEININGATLKSECCSSLGAAWGSPCTICQLDPICGKGFSRIKGT-QCEDINECEVFPGV 920

Query: 224  CPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
            C N   C+N+ G++ C   +CP+G   D   + CL
Sbjct: 921  CKN-GLCVNSRGSFKC---ECPNGMTLDATGRICL 951

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 19/113 (16%)
 Frame = +2

Query: 20   CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
            C  GF++  D + C DIDEC +          C N+ GSF C C P  TL P    CI+ 
Sbjct: 792  CPKGFVYKPDLKTCEDIDECESSPCINGV---CKNSPGSFICECSPESTLDPTKTICIET 848

Query: 197  -----------DECRIN-------SDICPNRKFCINTPGNYSCIEPKCPDGYN 301
                         C IN       S+ C +      +P     ++P C  G++
Sbjct: 849  IKGTCWQTVIDGRCEININGATLKSECCSSLGAAWGSPCTICQLDPICGKGFS 901
>sp|P53813|PROS_RAT Vitamin K-dependent protein S precursor
          Length = 675

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 43/114 (37%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
 Frame = +2

Query: 17  ICKIGFIWSGDRGCIDIDECATDVK-PGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
           ICK G  W GD+   DI+EC       G C   C NT GS+HC C  GF +      C D
Sbjct: 144 ICKPG--WQGDKCQFDINECKDPSNINGGCSQTCDNTPGSYHCSCKIGFAMLTNKKDCKD 201

Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKS 349
           VDEC +   +C     C N PG++ C   +CP+GY +D   K+C  +  C++ +
Sbjct: 202 VDECSLKPSVC-GTAVCKNIPGDFEC---ECPNGYRYDPSSKSCKDVDECSENT 251

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 49/140 (35%), Positives = 66/140 (47%), Gaps = 10/140 (7%)
 Frame = +2

Query: 11  HEICKIGF-IWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMK 184
           H  CKIGF + +  + C D+DEC+  +KP  C    C N  G F C CP G+   P +  
Sbjct: 183 HCSCKIGFAMLTNKKDCKDVDECS--LKPSVCGTAVCKNIPGDFECECPNGYRYDPSSKS 240

Query: 185 CIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFR--------LKACLSNCT 340
           C DVDEC  N+  C   + C+N PG YSC    C     F           +  CLS   
Sbjct: 241 CKDVDECSENT--CA--QLCVNYPGGYSCY---CDGKKGFKLAQDQRSCEGIPVCLSLDL 293

Query: 341 DKSPKCLTQASRIQYVVVQM 400
           DK+ + L  A +   VV+ +
Sbjct: 294 DKNYELLYLAEQFAGVVLYL 313
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,630,126
Number of Sequences: 369166
Number of extensions: 2205884
Number of successful extensions: 7931
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4787
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6496
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8598109270
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)