Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_O23
(870 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O77469|FBLN1_CAEEL Fibulin-1 precursor 89 2e-17
sp|P35556|FBN2_HUMAN Fibrillin-2 precursor 89 2e-17
sp|Q61555|FBN2_MOUSE Fibrillin-2 precursor 89 2e-17
sp|O88281|EGFL3_RAT Multiple EGF-like-domain protein 3 prec... 88 3e-17
sp|P35555|FBN1_HUMAN Fibrillin-1 precursor 87 6e-17
sp|P98133|FBN1_BOVIN Fibrillin-1 precursor (MP340) 87 6e-17
sp|Q08761|PROS_MOUSE Vitamin K-dependent protein S precursor 86 1e-16
sp|Q9TV36|FBN1_PIG Fibrillin-1 precursor 86 2e-16
sp|Q61554|FBN1_MOUSE Fibrillin-1 precursor 85 2e-16
sp|P53813|PROS_RAT Vitamin K-dependent protein S precursor 84 4e-16
>sp|O77469|FBLN1_CAEEL Fibulin-1 precursor
Length = 728
Score = 89.0 bits (219), Expect = 2e-17
Identities = 53/156 (33%), Positives = 76/156 (48%), Gaps = 13/156 (8%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGS--CQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
IC GF D C DIDEC+ G+ C C+NT GS+ C CPPG+ + P C
Sbjct: 499 ICDRGFALGPDGTKCEDIDECSIWAGSGNDLCMGGCINTKGSYLCQCPPGYKIQPDGRTC 558
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLK-------ACLSNCTDK 346
+DVDEC + + + K C+NT G++ C CP Y D K +C+ C+ +
Sbjct: 559 VDVDECAM-GECAGSDKVCVNTLGSFKCHSIDCPTNYIHDSLNKNQIADGYSCIKVCSTE 617
Query: 347 SPKCLTQASR---IQYVVVQMTGSMAQPVEVRVINT 445
+CL +R Q+ V ++ P+EV I T
Sbjct: 618 DTECLGNHTREVLYQFRAVPSLKTIISPIEVSRIVT 653
Score = 82.8 bits (203), Expect = 1e-15
Identities = 44/108 (40%), Positives = 60/108 (55%), Gaps = 5/108 (4%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
CK GF + D R C D++EC T + +C+ +CVN GS+ C+C GF L P KC D+
Sbjct: 459 CKPGFQLASDGRRCEDVNECTTGI--AACEQKCVNIPGSYQCICDRGFALGPDGTKCEDI 516
Query: 197 DECRI----NSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
DEC I +D+C CINT G+Y C +CP GY + C+
Sbjct: 517 DECSIWAGSGNDLCMGG--CINTKGSYLC---QCPPGYKIQPDGRTCV 559
Score = 65.1 bits (157), Expect = 2e-10
Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 3/137 (2%)
Frame = +2
Query: 8 KHEICKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTM 181
K +C G+ +G G C D++EC + G C +C+N G++ C C PG+
Sbjct: 371 KGNLCAHGYEVNGATGFCEDVNEC----QQGVCGSMECINLPGTYKCKCGPGYEFNDAKK 426
Query: 182 KCIDVDEC-RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
+C DVDEC + +C CINT G++ C KC G F+L + C D + +C
Sbjct: 427 RCEDVDECIKFAGHVCDLSAECINTIGSFEC---KCKPG----FQLASDGRRCEDVN-EC 478
Query: 359 LTQASRIQYVVVQMTGS 409
T + + V + GS
Sbjct: 479 TTGIAACEQKCVNIPGS 495
Score = 63.9 bits (154), Expect = 5e-10
Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = +2
Query: 56 CIDIDECATDV-KPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPN 232
C D+DEC +C+NT GSF C C PGF L +C DV+EC C
Sbjct: 428 CEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGFQLASDGRRCEDVNECTTGIAACEQ 487
Query: 233 RKFCINTPGNYSCIEPKCPDGY 298
+ C+N PG+Y CI C G+
Sbjct: 488 K--CVNIPGSYQCI---CDRGF 504
Score = 60.5 bits (145), Expect = 6e-09
Identities = 36/116 (31%), Positives = 51/116 (43%), Gaps = 23/116 (19%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHC------------------- 142
C +G+++ C+D+DEC YQC NT GS+ C
Sbjct: 268 CPMGWLFQHGH-CVDVDECNLGSHDCGPLYQCRNTQGSYRCDAKKCGDGELQNPMTGECT 326
Query: 143 --LCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEP--KCPDGY 298
CP G+ YPK C D+DEC + C + C+NTPG++ C + C GY
Sbjct: 327 SITCPNGY--YPKNGMCNDIDEC-VTGHNCGAGEECVNTPGSFRCQQKGNLCAHGY 379
Score = 50.4 bits (119), Expect = 6e-06
Identities = 37/138 (26%), Positives = 48/138 (34%), Gaps = 46/138 (33%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCL----------------- 145
C+ GF + D C+D +EC T P + CVNT G + C
Sbjct: 180 CRSGFDLAPDGMACVDRNECLTRQSPCTQSEDCVNTIGGYICQRRISRLVPHRHRANRIG 239
Query: 146 ----------------------------CPPGFTLYPKTMKCIDVDECRINSDICPNRKF 241
CP G+ + C+DVDEC + S C
Sbjct: 240 NAPRRMRDDPYSRAGEYREASQANTEFGCPMGWLF--QHGHCVDVDECNLGSHDCGPLYQ 297
Query: 242 CINTPGNYSCIEPKCPDG 295
C NT G+Y C KC DG
Sbjct: 298 CRNTQGSYRCDAKKCGDG 315
Score = 48.5 bits (114), Expect = 2e-05
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Frame = +2
Query: 68 DECATDVKPGSCQYQCVNTYGS-FHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFC 244
D CA+ C++ C + G C C GF L P M C+D +EC C + C
Sbjct: 157 DRCASS----HCEHLCHDRGGEKVECSCRSGFDLAPDGMACVDRNECLTRQSPCTQSEDC 212
Query: 245 INTPGNYSC 271
+NT G Y C
Sbjct: 213 VNTIGGYIC 221
>sp|P35556|FBN2_HUMAN Fibrillin-2 precursor
Length = 2911
Score = 89.0 bits (219), Expect = 2e-17
Identities = 46/117 (39%), Positives = 60/117 (51%), Gaps = 3/117 (2%)
Frame = +2
Query: 20 CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C G+ + DR GC DIDEC + G C QC N+ GS+ C C G+ L P C D+
Sbjct: 1226 CNPGYQATPDRQGCTDIDECM--IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI 1283
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL--SNCTDKSPKCL 361
DEC N DIC + C N PG Y C+ C DG+ +K C+ + C S C+
Sbjct: 1284 DECENNPDICDGGQ-CTNIPGEYRCL---CYDGFMASMDMKTCIDVNECDLNSNICM 1336
Score = 80.1 bits (196), Expect = 7e-15
Identities = 42/106 (39%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Frame = +2
Query: 20 CKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
CK+G+ CID+DEC+ KP C Y C NT GS+ C CP G+ L C D+
Sbjct: 2475 CKVGYTTDISGTSCIDLDECSQSPKP--CNYICKNTEGSYQCSCPRGYVLQEDGKTCKDL 2532
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
DEC+ C + C+NT G ++C KCP G F AC+ N
Sbjct: 2533 DECQTKQHNC--QFLCVNTLGGFTC---KCPPG--FTQHHTACIDN 2571
Score = 79.3 bits (194), Expect = 1e-14
Identities = 41/95 (43%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DI+EC PG C Y +C NT GSF C C GF L + C D+DECRI+ D+C
Sbjct: 1072 DINECKAF--PGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLC-GSG 1128
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
C+NTPG++ C +C +GY F + + NC D
Sbjct: 1129 ICVNTPGSFEC---ECFEGYESGFMM---MKNCMD 1157
Score = 77.8 bits (190), Expect = 4e-14
Identities = 44/95 (46%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+ GFI + G C D+DEC PG CQ C+NT GSF C CP G T KC D
Sbjct: 260 CRRGFIPNIRTGACQDVDEC--QAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCED 317
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+DEC I IC + C NT G+Y C+ CP GY
Sbjct: 318 IDECSIIPGICETGE-CSNTVGSYFCV---CPRGY 348
Score = 77.4 bits (189), Expect = 5e-14
Identities = 43/130 (33%), Positives = 62/130 (47%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C +G+ + CID+DEC ++ CVNT GS++C C GF P CID+D
Sbjct: 520 CNMGYKQDANGDCIDVDECTSNPCTNG---DCVNTPGSYYCKCHAGFQRTPTKQACIDID 576
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASRI 379
EC N +C N + C+N+ G++ CI N F L NC D +C T +
Sbjct: 577 ECIQNGVLCKNGR-CVNSDGSFQCI-------CNAGFELTTDGKNCVDHD-ECTTTNMCL 627
Query: 380 QYVVVQMTGS 409
+ + GS
Sbjct: 628 NGMCINEDGS 637
Score = 75.9 bits (185), Expect = 1e-13
Identities = 40/93 (43%), Positives = 53/93 (56%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C+ G+I +G + CID+DEC+ S QCVNT GS+ C C GFT C DVD
Sbjct: 1394 CREGWIGNGIK-CIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVD 1450
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
EC N ++C N + C+N PG Y C +C G+
Sbjct: 1451 ECAENINLCENGQ-CLNVPGAYRC---ECEMGF 1479
Score = 73.9 bits (180), Expect = 5e-13
Identities = 52/163 (31%), Positives = 73/163 (44%), Gaps = 5/163 (3%)
Frame = +2
Query: 50 RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
+ C+DID C + P C+ CVNT GSF C CP G L P C+D++EC ++ ++C
Sbjct: 1153 KNCMDIDGCERN--PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLC 1210
Query: 227 PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ--YVVV 394
N K C+N G Y C C GY + C + C + C TQ + + Y
Sbjct: 1211 RNGK-CVNMIGTYQC---SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECS 1266
Query: 395 QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
G P + R + + ENN + NIP Y L
Sbjct: 1267 CSEGYALMP-DGRSCADIDECENNPDICDGGQCTNIPGEYRCL 1308
Score = 73.6 bits (179), Expect = 7e-13
Identities = 41/120 (34%), Positives = 63/120 (52%), Gaps = 2/120 (1%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
+C GF+ S D + CID++EC D+ C + +C NT GSF C C G+++ T C
Sbjct: 1308 LCYDGFMASMDMKTCIDVNEC--DLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCT 1365
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
DVDEC I + C C+N PG++ C C +G+ + L C++ + +C A
Sbjct: 1366 DVDECEIGAHNCDMHASCLNIPGSFKC---SCREGWIGNGIKCIDLDECSNGTHQCSINA 1422
Score = 71.6 bits (174), Expect = 3e-12
Identities = 42/106 (39%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC GF + D + C+D DEC T C C+N GSF C+C PGF L P C
Sbjct: 600 ICNAGFELTTDGKNCVDHDECTTT---NMCLNGMCINEDGSFKCICKPGFVLAPNGRYCT 656
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
DVDEC+ IC N CIN+ G++ C CP G + C+
Sbjct: 657 DVDECQ-TPGICMN-GHCINSEGSFRC---DCPPGLAVGMDGRVCV 697
Score = 71.2 bits (173), Expect = 3e-12
Identities = 42/106 (39%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Frame = +2
Query: 62 DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DI+ECA D P C C N GS+ C C G+ CID+DEC +N +C N
Sbjct: 767 DINECALD--PDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDN-G 823
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
C NTPG+YSC CP GY F + C +S C+ A R
Sbjct: 824 LCRNTPGSYSC---TCPPGYVFRTETETCEDINECESNPCVNGACR 866
Score = 71.2 bits (173), Expect = 3e-12
Identities = 38/80 (47%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DIDEC PG CQ C+NT+GSF C CP G+ L T C D+DEC + +C
Sbjct: 1649 DIDECQE--LPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVC-GPG 1705
Query: 239 FCINTPGNYSCIEPKCPDGY 298
C NT GNY+CI CP Y
Sbjct: 1706 TCYNTLGNYTCI---CPPEY 1722
Score = 71.2 bits (173), Expect = 3e-12
Identities = 38/107 (35%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSCQ-YQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C IG+ D+ C D+DECA + + C N G+F C+CPPG P C+D
Sbjct: 2278 CPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVD 2337
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
+ECR IC N + C+N G+Y C +C +G+ CL N
Sbjct: 2338 ENECRTKPGICENGR-CVNIIGSYRC---ECNEGFQSSSSGTECLDN 2380
Score = 70.1 bits (170), Expect = 8e-12
Identities = 42/102 (41%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DIDEC V P C QC+NT GSF C C G+T CID+DEC + C
Sbjct: 2448 DIDECK--VMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC--NY 2503
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
C NT G+Y C CP GY K C L C K C
Sbjct: 2504 ICKNTEGSYQC---SCPRGYVLQEDGKTCKDLDECQTKQHNC 2542
Score = 68.6 bits (166), Expect = 2e-11
Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +2
Query: 59 IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
+DIDEC PG C C+N GSF C CP GF+ + C D+DEC ++C
Sbjct: 1806 VDIDECKEI--PGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 1863
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
CIN+PG+Y C +C G+
Sbjct: 1864 ADCINSPGSYRC---ECAAGF 1881
Score = 68.2 bits (165), Expect = 3e-11
Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 3/116 (2%)
Frame = +2
Query: 20 CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C+ GF + + C D+DEC + + CQ+ C N G + C CP G+ + + +C+D
Sbjct: 2598 CQRGFSLDATGLNCEDVDECDGNHR---CQHGCQNILGGYRCGCPQGYIQHYQWNQCVDE 2654
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
+EC N + C + C NT G+Y C CP G++FD AC ++ C+ C
Sbjct: 2655 NECS-NPNACGSAS-CYNTLGSYKCA---CPSGFSFDQFSSACHDVNECSSSKNPC 2705
Score = 67.8 bits (164), Expect = 4e-11
Identities = 38/115 (33%), Positives = 53/115 (46%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
+C GF + + C+DIDEC++ +C N GSF CLC G+ L P CID
Sbjct: 1957 LCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDT 2016
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCL 361
+EC C + C N G++ CI CP GY ++ C + CL
Sbjct: 2017 NECVALPGSC-SPGTCQNLEGSFRCI---CPPGYEVKSENCIDINECDEDPNICL 2067
Score = 66.6 bits (161), Expect = 8e-11
Identities = 42/109 (38%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C GF G C D+DECA ++ C+ QC+N G++ C C GFT + C D+
Sbjct: 1435 CSEGFTGDGFT-CSDVDECAENIN--LCENGQCLNVPGAYRCECEMGFTPASDSRSCQDI 1491
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
DEC +IC + C N PG + CI C DGY D NCTD
Sbjct: 1492 DECSF-QNICVSGT-CNNLPGMFHCI---CDDGYELD----RTGGNCTD 1531
Score = 66.2 bits (160), Expect = 1e-10
Identities = 36/93 (38%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GF C DI+ECA + P C +C+NT+GS+ C CP G+ L C D+D
Sbjct: 2238 CNEGFEPGPMMNCEDINECAQN--PLLCALRCMNTFGSYECTCPIGYALREDQKMCKDLD 2295
Query: 200 ECRINSDICPNR-KFCINTPGNYSCIEPKCPDG 295
EC C +R C N G + CI CP G
Sbjct: 2296 ECAEGLHDCESRGMMCKNLIGTFMCI---CPPG 2325
Score = 65.1 bits (157), Expect = 2e-10
Identities = 44/113 (38%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATD--VKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
C++GF + D R C DIDEC+ G+C N G FHC+C G+ L C
Sbjct: 1475 CEMGFTPASDSRSCQDIDECSFQNICVSGTCN----NLPGMFHCICDDGYELDRTGGNCT 1530
Query: 191 DVDECR--INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
D+DEC IN C N C+NTPG Y C CP DF+L C D
Sbjct: 1531 DIDECADPIN---CVN-GLCVNTPGRYEC---NCPP----DFQLNPTGVGCVD 1572
Score = 62.4 bits (150), Expect = 2e-09
Identities = 39/106 (36%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC GF S D+ C+D+DEC C NT GS++CLC PGF L C+D
Sbjct: 1917 ICHNGFKASQDQTMCMDVDECERHPCGNGT---CKNTVGSYNCLCYPGFEL-THNNDCLD 1972
Query: 194 VDEC-RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
+DEC +C N + C N G++ C+ C +GY K C+
Sbjct: 1973 IDECSSFFGQVCRNGR-CFNEIGSFKCL---CNEGYELTPDGKNCI 2014
Score = 60.5 bits (145), Expect = 6e-09
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
D++EC PG C QC+NT GSF C CP G+ L ++C+D DEC I + C N
Sbjct: 2170 DVNECLES--PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGT 2226
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
C N G++ C C +G+ + NC D
Sbjct: 2227 -CTNVIGSFEC---NCNEGFE-----PGPMMNCED 2252
Score = 60.5 bits (145), Expect = 6e-09
Identities = 32/81 (39%), Positives = 41/81 (50%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
C+D +EC+ GS C NT GS+ C CP GF+ + C DV+EC + + C
Sbjct: 2651 CVDENECSNPNACGSAS--CYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPC--N 2706
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
C NT G Y C CP GY
Sbjct: 2707 YGCSNTEGGYLC---GCPPGY 2724
Score = 57.0 bits (136), Expect = 7e-08
Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +2
Query: 50 RGCIDIDECATD---VKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
R CIDIDEC + G C+ NT GS+ C CPPG+ +T C D++EC N
Sbjct: 805 RNCIDIDECLVNRLLCDNGLCR----NTPGSYSCTCPPGYVFRTETETCEDINECESNP- 859
Query: 221 ICPNRKFCINTPGNYSC 271
C N C N G+++C
Sbjct: 860 -CVNGA-CRNNLGSFNC 874
Score = 57.0 bits (136), Expect = 7e-08
Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C GF S + C+D +EC P C + CV+ GS+ C+C GF C+DV
Sbjct: 1877 CAAGFKLSPNGACVDRNECLEI--PNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDV 1934
Query: 197 DECRINSDICPNRKFCINTPGNYSCI 274
DEC + C N C NT G+Y+C+
Sbjct: 1935 DECERHP--CGNGT-CKNTVGSYNCL 1957
Score = 56.6 bits (135), Expect = 9e-08
Identities = 36/106 (33%), Positives = 46/106 (43%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
CID +EC + + C NT GSF C C GF+L + C DVDEC N +
Sbjct: 2568 CIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRC---Q 2624
Query: 236 KFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQAS 373
C N G Y C CP GY ++ C+ +P AS
Sbjct: 2625 HGCQNILGGYRC---GCPQGYIQHYQWNQCVDENECSNPNACGSAS 2667
Score = 55.8 bits (133), Expect = 1e-07
Identities = 33/90 (36%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC G+ + CIDI+EC D P C + C NT G F CLCPPGF L +C D
Sbjct: 2041 ICPPGYEVKSEN-CIDINECDED--PNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2097
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPK 283
+ FC N C PK
Sbjct: 2098 T-----------RQSFCFTNFENGKCSVPK 2116
Score = 55.1 bits (131), Expect = 3e-07
Identities = 28/81 (34%), Positives = 42/81 (51%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
C DIDEC+ C+N+ GS+ C C GF L P C+D +EC ++C +
Sbjct: 1847 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVC-SH 1904
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
C++ G+Y CI C +G+
Sbjct: 1905 GLCVDLQGSYQCI---CHNGF 1922
Score = 53.1 bits (126), Expect = 1e-06
Identities = 27/61 (44%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
ICK GF+ + + R C D+DEC T PG C C+N+ GSF C CPPG + C+
Sbjct: 641 ICKPGFVLAPNGRYCTDVDECQT---PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCV 697
Query: 191 D 193
D
Sbjct: 698 D 698
Score = 49.7 bits (117), Expect = 1e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Frame = +2
Query: 41 SGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
+G++ C + C T PG+ ++ + C PGFT T K +D+DEC+
Sbjct: 1770 AGNKPC---EPCPT---PGTADFKTI-------CGNIPGFTFDIHTGKAVDIDECKEIPG 1816
Query: 221 ICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
IC N CIN G++ C +CP G++++ L C + C++ C A I
Sbjct: 1817 ICAN-GVCINQIGSFRC---ECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1867
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/58 (43%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV--DECRINSD 220
C D++EC +V PG C +CVN+ GSFHC CP G TL C+D+ ++C + D
Sbjct: 952 CEDVNEC--EVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWD 1007
Score = 48.9 bits (115), Expect = 2e-05
Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +2
Query: 11 HEICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
H IC G+ G C DIDECA + CVNT G + C CPP F L P + C
Sbjct: 1513 HCICDDGYELDRTGGNCTDIDECADPIN--CVNGLCVNTPGRYECNCPPDFQLNPTGVGC 1570
Query: 188 ID--VDECRINSDICPNRKFCINTPGNYSC 271
+D V C + KF G+ SC
Sbjct: 1571 VDNRVGNCYL--------KFGPRGDGSLSC 1592
Score = 48.5 bits (114), Expect = 2e-05
Identities = 28/73 (38%), Positives = 38/73 (52%)
Frame = +2
Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
+C+ T S+ C C G+ CIDVDEC S+ C N C+NTPG+Y C KC
Sbjct: 508 RCIPTVSSYRCECNMGYK-QDANGDCIDVDEC--TSNPCTNGD-CVNTPGSYYC---KCH 560
Query: 290 DGYNFDFRLKACL 328
G+ +AC+
Sbjct: 561 AGFQRTPTKQACI 573
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 10/100 (10%)
Frame = +2
Query: 59 IDIDECATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECR 208
I C ++ + + +C T G+ CP G K + C DV+EC
Sbjct: 901 IQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARI-KGVTCEDVNECE 959
Query: 209 INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
+ +CPN + C+N+ G++ C +CP+G D + CL
Sbjct: 960 VFPGVCPNGR-CVNSKGSFHC---ECPEGLTLDGTGRVCL 995
Score = 46.6 bits (109), Expect = 9e-05
Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C DIDEC+ + PG C+ +C NT GS+ C+CP G+ +CID
Sbjct: 315 CEDIDECS--IIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 359
Score = 44.7 bits (104), Expect = 3e-04
Identities = 37/116 (31%), Positives = 49/116 (42%), Gaps = 18/116 (15%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C G+ S D R C DIDEC PG C C NT G++ C+CPP + C+D
Sbjct: 1676 CPQGYYLSEDTRICEDIDECFAH--PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMD 1733
Query: 194 VDEC----RINSDICPN-------RKFC-----INTPGNYSCIEPKCPDGYNFDFR 313
+ + N C N ++ C + GN C EP CP DF+
Sbjct: 1734 MRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAGNKPC-EP-CPTPGTADFK 1787
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Frame = +2
Query: 134 FHCLCP--PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFD 307
++ LCP GF P T+ D+DEC+ +C CINT G++ C +CP GY
Sbjct: 1628 YYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQC---ECPQGYYLS 1683
Query: 308 FRLKAC 325
+ C
Sbjct: 1684 EDTRIC 1689
Score = 36.2 bits (82), Expect = 0.12
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C G+++ + C DI+EC ++ C N GSF+C C PG L + CID
Sbjct: 836 CPPGYVFRTETETCEDINECESNPCVNGA---CRNNLGSFNCECSPGSKLSSTGLICID 891
>sp|Q61555|FBN2_MOUSE Fibrillin-2 precursor
Length = 2907
Score = 88.6 bits (218), Expect = 2e-17
Identities = 46/113 (40%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
Frame = +2
Query: 20 CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C G+ + DR GC DIDEC + G C QC N+ GS+ C C G+ L P C D+
Sbjct: 1220 CNPGYQATPDRQGCTDIDECM--IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADI 1277
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSP 352
DEC N DIC + C N PG Y C+ C DG+ +K C+ N D +P
Sbjct: 1278 DECENNPDICDGGQ-CTNIPGEYRCL---CYDGFMASMDMKTCIDVNECDLNP 1326
Score = 83.2 bits (204), Expect = 9e-16
Identities = 45/106 (42%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
Frame = +2
Query: 29 GFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDEC 205
G I +G C DI+EC PG C Y +C NT GSF C C GF L + C D+DEC
Sbjct: 1055 GDILTGRPFCKDINECKAF--PGMCTYGKCRNTIGSFKCRCNNGFALDMEERNCTDIDEC 1112
Query: 206 RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
RI+ D+C C+NTPG++ C +C +GY F + + NC D
Sbjct: 1113 RISPDLC-GSGICVNTPGSFEC---ECFEGYESGFMM---MKNCMD 1151
Score = 78.6 bits (192), Expect = 2e-14
Identities = 40/106 (37%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Frame = +2
Query: 20 CKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
CK+G+ C+D+DEC+ KP C + C NT GS+ C CP G+ L C D+
Sbjct: 2469 CKVGYTMDISGTACVDLDECSQSPKP--CNFICKNTKGSYQCSCPRGYVLQEDGKTCKDL 2526
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
DEC+ C + C+NT G ++C KCP G F AC+ N
Sbjct: 2527 DECQTKQHNC--QFLCVNTLGGFTC---KCPPG--FTQHHTACIDN 2565
Score = 77.8 bits (190), Expect = 4e-14
Identities = 40/93 (43%), Positives = 54/93 (58%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C+ G++ +G + CID+DECA S QCVNT GS+ C C GFT C DVD
Sbjct: 1388 CREGWVGNGIK-CIDLDECANGTHQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVD 1444
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
EC N+++C N + C+N PG Y C +C G+
Sbjct: 1445 ECAENTNLCENGQ-CLNVPGAYRC---ECEMGF 1473
Score = 77.4 bits (189), Expect = 5e-14
Identities = 43/130 (33%), Positives = 62/130 (47%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C +G+ + CID+DEC ++ CVNT GS++C C GF P CID+D
Sbjct: 514 CNMGYKQDANGDCIDVDECTSNPCSNG---DCVNTPGSYYCKCHAGFQRTPTKQACIDID 570
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASRI 379
EC N +C N + C+N+ G++ CI N F L NC D +C T +
Sbjct: 571 ECIQNGVLCKNGR-CVNSDGSFQCI-------CNAGFELTTDGKNCVDHD-ECTTTNMCL 621
Query: 380 QYVVVQMTGS 409
+ + GS
Sbjct: 622 NGMCINEDGS 631
Score = 76.6 bits (187), Expect = 8e-14
Identities = 53/163 (32%), Positives = 74/163 (45%), Gaps = 5/163 (3%)
Frame = +2
Query: 50 RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
+ C+DIDEC + P C+ CVNT GSF C CP G L P C+D++EC ++ ++C
Sbjct: 1147 KNCMDIDECERN--PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLC 1204
Query: 227 PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ--YVVV 394
N K C+N G Y C C GY + C + C + C TQ + + Y
Sbjct: 1205 RNGK-CVNMIGTYQC---SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECS 1260
Query: 395 QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
G P + R + + ENN + NIP Y L
Sbjct: 1261 CSEGYALMP-DGRSCADIDECENNPDICDGGQCTNIPGEYRCL 1302
Score = 76.6 bits (187), Expect = 8e-14
Identities = 42/120 (35%), Positives = 63/120 (52%), Gaps = 2/120 (1%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
+C GF+ S D + CID++EC D+ P C + +C NT GSF C C G+++ T C
Sbjct: 1302 LCYDGFMASMDMKTCIDVNEC--DLNPNICMFGECENTKGSFICHCQLGYSVKKGTTGCT 1359
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
DVDEC I + C C+N PG++ C C +G+ + L C + + +C A
Sbjct: 1360 DVDECEIGAHNCDMHASCLNVPGSFKC---SCREGWVGNGIKCIDLDECANGTHQCSINA 1416
Score = 74.3 bits (181), Expect = 4e-13
Identities = 41/95 (43%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+ GFI + G C D+DEC PG CQ C+NT GSF C CP G T KC D
Sbjct: 261 CRPGFIPNIRTGACQDVDEC--QAIPGLCQGGNCINTVGSFECRCPAGHKQSETTQKCED 318
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+DEC + +C C NT G+Y C+ CP G+
Sbjct: 319 IDECSVIPGVCETGD-CSNTVGSYFCL---CPRGF 349
Score = 72.0 bits (175), Expect = 2e-12
Identities = 38/80 (47%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DIDEC PG CQ C+NT+GSF C CP G+ L +T C D+DEC + +C
Sbjct: 1643 DIDECQE--LPGLCQGGNCINTFGSFQCECPQGYYLSEETRICEDIDECFAHPGVC-GPG 1699
Query: 239 FCINTPGNYSCIEPKCPDGY 298
C NT GNY+CI CP Y
Sbjct: 1700 TCYNTLGNYTCI---CPPEY 1716
Score = 70.5 bits (171), Expect = 6e-12
Identities = 42/102 (41%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DIDEC V P C QCVNT GSF C C G+T+ C+D+DEC + C
Sbjct: 2442 DIDECK--VMPSLCTNGQCVNTMGSFRCFCKVGYTMDISGTACVDLDECSQSPKPC--NF 2497
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
C NT G+Y C CP GY K C L C K C
Sbjct: 2498 ICKNTKGSYQC---SCPRGYVLQEDGKTCKDLDECQTKQHNC 2536
Score = 70.1 bits (170), Expect = 8e-12
Identities = 41/95 (43%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC GF + D + C+D DEC T C C+N GSF C+C PGF L P C
Sbjct: 594 ICNAGFELTTDGKNCVDHDECTTT---NMCLNGMCINEDGSFKCVCKPGFILAPNGRYCT 650
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDG 295
DVDEC+ IC N CIN G++ C CP G
Sbjct: 651 DVDECQ-TPGICMN-GHCINNEGSFRC---DCPPG 680
Score = 70.1 bits (170), Expect = 8e-12
Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 20 CKIGF-IWSGDRGCIDIDECATDVKPGSCQ-YQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C +G+ + + C D+DECA + + C N G+F C+CPPG P C+D
Sbjct: 2272 CPVGYGLREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVD 2331
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
+ECR IC N + C+N G+Y C +C +G+ CL N
Sbjct: 2332 ENECRTKPGICENGR-CVNIIGSYRC---ECNEGFQSSSSGTECLDN 2374
Score = 68.6 bits (166), Expect = 2e-11
Identities = 44/123 (35%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
Frame = +2
Query: 11 HEICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKC 187
H +C G + D DI+ECA D P C C N G++ C C G+ C
Sbjct: 746 HGLCSSGIGITVDGR--DINECALD--PDICANGICENLRGTYRCNCNSGYEPDASGRNC 801
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQ 367
ID+DEC +N +C N C NTPG+YSC CP GY + C +S C+
Sbjct: 802 IDIDECLVNRLLCDN-GLCRNTPGSYSC---TCPPGYVLPTETETCEDVNECESNPCVNG 857
Query: 368 ASR 376
A R
Sbjct: 858 ACR 860
Score = 68.6 bits (166), Expect = 2e-11
Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +2
Query: 59 IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
+DIDEC PG C C+N GSF C CP GF+ + C D+DEC ++C
Sbjct: 1800 VDIDECKEI--PGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 1857
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
CIN+PG+Y C +C G+
Sbjct: 1858 ADCINSPGSYRC---ECAAGF 1875
Score = 68.2 bits (165), Expect = 3e-11
Identities = 45/112 (40%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C++GF + D R C DIDEC+ C + C N G FHC+C G+ L C D
Sbjct: 1469 CEMGFTPASDSRSCQDIDECSFQ---NICVFGTCNNLPGMFHCICDDGYELDRTGGNCTD 1525
Query: 194 VDECR--INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
+DEC IN C N C+NTPG Y C CP DF+L A C D
Sbjct: 1526 IDECADPIN---CVN-GLCVNTPGRYEC---NCPP----DFQLNATGVGCVD 1566
Score = 67.8 bits (164), Expect = 4e-11
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 2/117 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
+C GF + + C+DIDEC++ +C N GSF CLC G+ L P CID
Sbjct: 1951 LCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDT 2010
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCL 361
+EC C + C N G++ CI CP GY + R + C ++ C + CL
Sbjct: 2011 NECVALPGSC-SPGTCQNLEGSFRCI---CPPGY--EVRSENCIDINECDEDPNICL 2061
Score = 67.4 bits (163), Expect = 5e-11
Identities = 36/93 (38%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GF C DI+ECA + P C ++C+NT+GS+ C CP G+ L C D+D
Sbjct: 2232 CNEGFEPGPMMNCEDINECAQN--PLLCAFRCMNTFGSYECTCPVGYGLREDQKMCKDLD 2289
Query: 200 ECRINSDICPNR-KFCINTPGNYSCIEPKCPDG 295
EC C +R C N G + CI CP G
Sbjct: 2290 ECAEGLHDCESRGMMCKNLIGTFMCI---CPPG 2319
Score = 65.9 bits (159), Expect = 1e-10
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
Frame = +2
Query: 20 CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C+ GF + + C D+DEC + + CQ+ C N G + C CP G + + +C+D
Sbjct: 2592 CQRGFSLDASGLNCEDVDECDGNHR---CQHGCQNILGGYRCGCPHGDVQHYQWNQCVDE 2648
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
+EC N C + C NT G+Y C CP G++FD AC ++ C+ C
Sbjct: 2649 NECS-NPGACGSAS-CYNTLGSYKCA---CPSGFSFDQFSSACHDVNECSSSKNPC 2699
Score = 65.5 bits (158), Expect = 2e-10
Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C G+ D R C DIDEC + P C QC N G + CLC GF CID
Sbjct: 1261 CSEGYALMPDGRSCADIDECENN--PDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 1318
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
V+EC +N +IC + C NT G++ C C GY+ +K + CTD
Sbjct: 1319 VNECDLNPNICMFGE-CENTKGSFIC---HCQLGYS----VKKGTTGCTD 1360
Score = 63.9 bits (154), Expect = 5e-10
Identities = 42/109 (38%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C GF G C D+DECA + C+ QC+N G++ C C GFT + C D+
Sbjct: 1429 CSEGFTGDGFT-CSDVDECAENTN--LCENGQCLNVPGAYRCECEMGFTPASDSRSCQDI 1485
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
DEC +IC C N PG + CI C DGY D NCTD
Sbjct: 1486 DECSF-QNICVFGT-CNNLPGMFHCI---CDDGYELD----RTGGNCTD 1525
Score = 63.9 bits (154), Expect = 5e-10
Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC GF S D+ C+D+DEC + C NT GS++CLC PGF L C+D
Sbjct: 1911 ICNNGFKASQDQTMCMDVDECE---RHPCANGTCKNTVGSYNCLCYPGFEL-THNNDCLD 1966
Query: 194 VDEC-RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
+DEC +C N + C N G++ C+ C +GY K C+
Sbjct: 1967 IDECSSFFGQVCRNGR-CFNEIGSFKCL---CNEGYELTPDGKNCI 2008
Score = 62.8 bits (151), Expect = 1e-09
Identities = 33/82 (40%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Frame = +2
Query: 56 CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPN 232
C+D +EC+ PG+C C NT GS+ C CP GF+ + C DV+EC + + C
Sbjct: 2645 CVDENECSN---PGACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCSY 2701
Query: 233 RKFCINTPGNYSCIEPKCPDGY 298
C NT G Y C CP GY
Sbjct: 2702 G--CSNTEGGYLC---GCPPGY 2718
Score = 59.3 bits (142), Expect = 1e-08
Identities = 36/95 (37%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
D++EC PG C QC+NT GSF C CP G+ L ++C+D DEC I + C N
Sbjct: 2164 DVNECLES--PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGT 2220
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
C N G C E C +G+ + NC D
Sbjct: 2221 -CTNVIG---CFECTCNEGFE-----PGPMMNCED 2246
Score = 57.8 bits (138), Expect = 4e-08
Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Frame = +2
Query: 50 RGCIDIDECATD---VKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
R CIDIDEC + G C+ NT GS+ C CPPG+ L +T C DV+EC N
Sbjct: 799 RNCIDIDECLVNRLLCDNGLCR----NTPGSYSCTCPPGYVLPTETETCEDVNECESNP- 853
Query: 221 ICPNRKFCINTPGNYSC 271
C N C N G++ C
Sbjct: 854 -CVNGA-CRNNLGSFHC 868
Score = 57.4 bits (137), Expect = 5e-08
Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C GF S + C+D +EC P C + CV+ GS+ C+C GF C+DV
Sbjct: 1871 CAAGFKLSPNGACVDRNECLEI--PNVCSHGLCVDLQGSYQCICNNGFKASQDQTMCMDV 1928
Query: 197 DECRINSDICPNRKFCINTPGNYSCI 274
DEC + C N C NT G+Y+C+
Sbjct: 1929 DECERHP--CANGT-CKNTVGSYNCL 1951
Score = 55.1 bits (131), Expect = 3e-07
Identities = 28/81 (34%), Positives = 42/81 (51%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
C DIDEC+ C+N+ GS+ C C GF L P C+D +EC ++C +
Sbjct: 1841 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVC-SH 1898
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
C++ G+Y CI C +G+
Sbjct: 1899 GLCVDLQGSYQCI---CNNGF 1916
Score = 54.7 bits (130), Expect = 3e-07
Identities = 32/90 (35%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC G+ + CIDI+EC D P C + C NT G F C+CPPGF L +C D
Sbjct: 2035 ICPPGYEVRSEN-CIDINECDED--PNICLFGSCTNTPGGFQCICPPGFVLSDNGRRCFD 2091
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPK 283
+ FC N C PK
Sbjct: 2092 T-----------RQSFCFTNFENGKCSVPK 2110
Score = 52.8 bits (125), Expect = 1e-06
Identities = 27/61 (44%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
+CK GFI + + R C D+DEC T PG C C+N GSF C CPPG + C+
Sbjct: 635 VCKPGFILAPNGRYCTDVDECQT---PGICMNGHCINNEGSFRCDCPPGLAVGVDGRVCV 691
Query: 191 D 193
D
Sbjct: 692 D 692
Score = 51.2 bits (121), Expect = 4e-06
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
Frame = +2
Query: 59 IDIDECATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECR 208
I + C ++ + + +C T G CP GF K + C DV+EC
Sbjct: 895 IQDNRCEVNINGATLKSECCATLGGAWGSPCERCELDAACPRGFARI-KGVTCEDVNECE 953
Query: 209 INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
+ +CPN + C+N+ G++ C +CP+G D + CL
Sbjct: 954 VFPGVCPNGR-CVNSKGSFHC---ECPEGLTLDGTGRVCL 989
Score = 49.7 bits (117), Expect = 1e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Frame = +2
Query: 41 SGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
+G++ C + C T PG+ ++ + C PGFT T K +D+DEC+
Sbjct: 1764 AGNKPC---EPCPT---PGTADFKTI-------CGNIPGFTFDIHTGKAVDIDECKEIPG 1810
Query: 221 ICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
IC N CIN G++ C +CP G++++ L C + C++ C A I
Sbjct: 1811 ICAN-GVCINQIGSFRC---ECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCI 1861
Score = 49.3 bits (116), Expect = 1e-05
Identities = 26/60 (43%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C GF C D++EC +V PG C +CVN+ GSFHC CP G TL C+D+
Sbjct: 934 CPRGFARIKGVTCEDVNEC--EVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDI 991
Score = 48.9 bits (115), Expect = 2e-05
Identities = 28/73 (38%), Positives = 38/73 (52%)
Frame = +2
Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
+C+ T S+ C C G+ CIDVDEC S+ C N C+NTPG+Y C KC
Sbjct: 502 RCIPTVSSYRCRCNMGYK-QDANGDCIDVDEC--TSNPCSNGD-CVNTPGSYYC---KCH 554
Query: 290 DGYNFDFRLKACL 328
G+ +AC+
Sbjct: 555 AGFQRTPTKQACI 567
Score = 48.5 bits (114), Expect = 2e-05
Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C DIDEC+ V PG C+ C NT GS+ CLCP GF +CID
Sbjct: 316 CEDIDECS--VIPGVCETGDCSNTVGSYFCLCPRGFVTSTDGSRCID 360
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/116 (31%), Positives = 49/116 (42%), Gaps = 18/116 (15%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C G+ S + R C DIDEC PG C C NT G++ C+CPP + C+D
Sbjct: 1670 CPQGYYLSEETRICEDIDECFAH--PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMD 1727
Query: 194 VDEC----RINSDICPN-------RKFC-----INTPGNYSCIEPKCPDGYNFDFR 313
+ + N C N ++ C + GN C EP CP DF+
Sbjct: 1728 MRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAGNKPC-EP-CPTPGTADFK 1781
Score = 41.2 bits (95), Expect = 0.004
Identities = 32/116 (27%), Positives = 43/116 (37%), Gaps = 14/116 (12%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPP--------------G 157
C + F GD E V SC +G+ CPP G
Sbjct: 1572 CYLKFGPRGDGSLSCNTEAGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEHYTLCPGGEG 1631
Query: 158 FTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
F P T+ D+DEC+ +C CINT G++ C +CP GY + C
Sbjct: 1632 FRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQC---ECPQGYYLSEETRIC 1683
Score = 38.5 bits (88), Expect = 0.024
Identities = 26/99 (26%), Positives = 38/99 (38%), Gaps = 18/99 (18%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV-----------DE 202
C D++EC ++ C N GSFHC C PG L + CID +
Sbjct: 843 CEDVNECESNPCVNGA---CRNNLGSFHCECSPGSKLSSTGLICIDSLKGTCWLNIQDNR 899
Query: 203 CRIN-------SDICPNRKFCINTPGNYSCIEPKCPDGY 298
C +N S+ C +P ++ CP G+
Sbjct: 900 CEVNINGATLKSECCATLGGAWGSPCERCELDAACPRGF 938
>sp|O88281|EGFL3_RAT Multiple EGF-like-domain protein 3 precursor (Multiple epidermal
growth factor-like domains 6)
Length = 1574
Score = 88.2 bits (217), Expect = 3e-17
Identities = 51/126 (40%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = +2
Query: 38 WS---GDRGCI-DIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDEC 205
WS G GC+ D+DECA+ G C+ C NT G F+C CPPG+ L C DVDEC
Sbjct: 111 WSQKPGQEGCLSDVDECAS--ANGGCEGPCCNTVGGFYCRCPPGYQLQGDGKTCQDVDEC 168
Query: 206 RINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL--SNCTDKSPKCLTQASRI 379
R ++ C +R C+NTPG+Y C +C G+ + CL S+CT + C Q +
Sbjct: 169 RAHNGGCQHR--CVNTPGSYLC---ECKPGFRLHTDGRTCLAISSCTLGNGGCQHQC--V 221
Query: 380 QYVVVQ 397
Q V Q
Sbjct: 222 QLTVTQ 227
Score = 62.8 bits (151), Expect = 1e-09
Identities = 37/105 (35%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C G+ D + CIDID+CA CQ C NT G + C C G+ L C DV
Sbjct: 360 CPRGYELDEDQKTCIDIDDCANSP---CCQQACANTPGGYECSCFAGYRLNTDGCGCEDV 416
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS 331
DEC C + C N G++ C C GY D + C S
Sbjct: 417 DECASGHGGCEHH--CSNLAGSFQCF---CEAGYRLDEDRRGCTS 456
Score = 56.6 bits (135), Expect = 9e-08
Identities = 38/121 (31%), Positives = 53/121 (43%), Gaps = 4/121 (3%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C G+ + DR C D+DECA + C + C+NT GSF C+C G+ L +C +
Sbjct: 273 CHPGYQLAADRKTCEDVDECALGL--AQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRI 330
Query: 197 DECRINSDICPN---RKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQ 367
+ +NS N C +T C CP GY D K C+ + C Q
Sbjct: 331 EMEIVNSCEAGNGGCSHGCSHTSTGPLC---TCPRGYELDEDQKTCIDIDDCANSPCCQQ 387
Query: 368 A 370
A
Sbjct: 388 A 388
Score = 54.3 bits (129), Expect = 4e-07
Identities = 30/92 (32%), Positives = 40/92 (43%)
Frame = +2
Query: 50 RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICP 229
R C+ CA G C + C G HC C PG+ L C DVDEC + C
Sbjct: 243 RRCVRRSPCAEG--NGGCMHICQELRGLAHCGCHPGYQLAADRKTCEDVDECALGLAQCA 300
Query: 230 NRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
+ C+NT G++ C+ C GY + C
Sbjct: 301 HG--CLNTQGSFKCV---CHAGYELGADGRQC 327
Score = 48.5 bits (114), Expect = 2e-05
Identities = 21/56 (37%), Positives = 30/56 (53%)
Frame = +2
Query: 53 GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSD 220
GC D+DECA+ G C++ C N GSF C C G+ L C ++E ++ D
Sbjct: 412 GCEDVDECASG--HGGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCTSLEESVVDLD 465
Score = 30.0 bits (66), Expect = 8.7
Identities = 21/82 (25%), Positives = 32/82 (39%), Gaps = 11/82 (13%)
Frame = +2
Query: 74 CATDVKPGSCQYQCVNTY---GSFH-CLCPPGFTLYPKTMKC-------IDVDECRINSD 220
C + CQ +C + + G H C C PG P + +C ++C
Sbjct: 677 CKAGFQGERCQAECESGFFGPGCRHRCTCQPGVACDPVSGECRTQCPPGYQGEDC---GQ 733
Query: 221 ICPNRKFCINTPGNYSCIEPKC 286
CP F +N G+ SC+ C
Sbjct: 734 ECPVGTFGVNCSGSCSCVGAPC 755
>sp|P35555|FBN1_HUMAN Fibrillin-1 precursor
Length = 2871
Score = 87.0 bits (214), Expect = 6e-17
Identities = 47/118 (39%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
Frame = +2
Query: 20 CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C G+ + DR C+DIDEC+ + G C+ C N+ GS+ C C PGF L P C D+
Sbjct: 1182 CNPGYHSTPDRLFCVDIDECS--IMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDI 1239
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSPK-CLT 364
DEC N +IC + C N PG Y C+ C DG+ +K C+ N D +P CL+
Sbjct: 1240 DECEDNPNICDGGQ-CTNIPGEYRCL---CYDGFMASEDMKTCVDVNECDLNPNICLS 1293
Score = 79.7 bits (195), Expect = 1e-14
Identities = 41/95 (43%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DI+EC + P C + +C NT GSF C C GF L + C D+DECRI+ D+C R
Sbjct: 1028 DINECK--MIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC-GRG 1084
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
C+NTPG++ C KC +GY F + + NC D
Sbjct: 1085 QCVNTPGDFEC---KCDEGYESGFMM---MKNCMD 1113
Score = 79.0 bits (193), Expect = 2e-14
Identities = 40/113 (35%), Positives = 55/113 (48%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GFI S + CID+DECA+ QC+NT GSF C C G+ + P C+D++
Sbjct: 1916 CNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDIN 1975
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
EC + C C N G+Y CI CP GY+ + C ++ C
Sbjct: 1976 ECLLEPRKCAPGT-CQNLDGSYRCI---CPPGYSLQNEKCEDIDECVEEPEIC 2024
Score = 77.4 bits (189), Expect = 5e-14
Identities = 52/163 (31%), Positives = 75/163 (46%), Gaps = 5/163 (3%)
Frame = +2
Query: 50 RGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
+ C+DIDEC D P C+ C NT GS+ C CPPG L P CID++EC +++ +C
Sbjct: 1109 KNCMDIDECQRD--PLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLC 1166
Query: 227 PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ--YVVV 394
PN + C+N G Y C C GY+ C + C+ + C T + + Y
Sbjct: 1167 PNGR-CVNLIGKYQC---ACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECS 1222
Query: 395 QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
G P + R + + E+N + NIP Y L
Sbjct: 1223 CQPGFALMP-DQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264
Score = 73.9 bits (180), Expect = 5e-13
Identities = 42/95 (44%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+ GFI + G C D+DEC PG CQ C+NT GSF C CP G L + KC D
Sbjct: 231 CRRGFIPNIRTGACQDVDEC--QAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED 288
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+DEC IC + C NT +Y C KCP G+
Sbjct: 289 IDECSTIPGICEGGE-CTNTVSSYFC---KCPPGF 319
Score = 73.9 bits (180), Expect = 5e-13
Identities = 43/119 (36%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
Frame = +2
Query: 11 HEICKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
H ICK G+ C+D++EC KP C + C NT GS+ C CP G+ L C
Sbjct: 2426 HCICKTGYTPDITGTSCVDLNECNQAPKP--CNFICKNTEGSYQCSCPKGYILQEDGRSC 2483
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN--CTDKSPKC 358
D+DEC C + C+NT G ++C KCP G F +C+ N CT C
Sbjct: 2484 KDLDECATKQHNC--QFLCVNTIGGFTC---KCPPG--FTQHHTSCIDNNECTSDINLC 2535
Score = 73.2 bits (178), Expect = 9e-13
Identities = 46/129 (35%), Positives = 69/129 (53%), Gaps = 10/129 (7%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVK---PGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
C G+ + D R C+DI+EC + + PG+CQ N GS+ C+CPPG++L + KC
Sbjct: 1958 CNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQ----NLDGSYRCICPPGYSL--QNEKC 2011
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC----LSNCTDK--S 349
D+DEC +IC C NT G++ C+ CP+G++ + C +S C K
Sbjct: 2012 EDIDECVEEPEICALGT-CSNTEGSFKCL---CPEGFSLSSSGRRCQDLRMSYCYAKFEG 2067
Query: 350 PKCLTQASR 376
KC + SR
Sbjct: 2068 GKCSSPKSR 2076
Score = 72.0 bits (175), Expect = 2e-12
Identities = 37/83 (44%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
Frame = +2
Query: 59 IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
+DIDEC PG C+ C+N GSF C CP GF K + C D+DEC+ N +C
Sbjct: 1765 VDIDECREI--PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRN 1821
Query: 236 KFCINTPGNYSCIEPKCPDGYNF 304
CINT G+Y C C GY F
Sbjct: 1822 AECINTAGSYRC---DCKPGYRF 1841
Score = 71.6 bits (174), Expect = 3e-12
Identities = 42/106 (39%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
Frame = +2
Query: 20 CKIGF-IWSGDRGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMK-CI 190
C GF + S +R C DIDEC + P C + QCVNT G F C C G+ MK C+
Sbjct: 1055 CDSGFALDSEERNCTDIDECR--ISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCM 1112
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
D+DEC+ + +C C NT G+Y C +CP G+ + AC+
Sbjct: 1113 DIDECQRDPLLC-RGGVCHNTEGSYRC---ECPPGHQLSPNISACI 1154
Score = 70.9 bits (172), Expect = 4e-12
Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 4/109 (3%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSC---QYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
C +G++ DR C D DEC + C Q +C N G++ C+C PG+ P C
Sbjct: 2232 CPVGYVLREDRRMCKDEDEC--EEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGC 2289
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
+D +EC+ IC N + C+NT G+Y+C +C DG+ CL N
Sbjct: 2290 VDENECQTKPGICENGR-CLNTRGSYTC---ECNDGFTASPNQDECLDN 2334
Score = 70.1 bits (170), Expect = 8e-12
Identities = 38/94 (40%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C+ GF C DI+ECA + P C ++CVNTYGS+ C CP G+ L C D D
Sbjct: 2192 CEEGFEPGPMMTCEDINECAQN--PLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDED 2249
Query: 200 ECRINSDICPNRKF-CINTPGNYSCIEPKCPDGY 298
EC C ++ C N G Y CI C GY
Sbjct: 2250 ECEEGKHDCTEKQMECKNLIGTYMCI---CGPGY 2280
Score = 69.7 bits (169), Expect = 1e-11
Identities = 39/102 (38%), Positives = 52/102 (50%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C G+I G + C D+DEC+ S C NT GS+ CLC G+T C D+D
Sbjct: 1350 CSPGWIGDGIK-CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLD 1406
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
EC N ++C N + C+N PG Y C +C G+ KAC
Sbjct: 1407 ECSENLNLCGNGQ-CLNAPGGYRC---ECDMGFVPSADGKAC 1444
Score = 69.7 bits (169), Expect = 1e-11
Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DIDEC PG CQ +C+NT+GSF C CP G+ L T C DV+EC P
Sbjct: 1606 DIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT- 1662
Query: 239 FCINTPGNYSCIEPKCPDGYN--------FDFRLKACLSNCTDKSPKC 358
C NT GNY+CI CP Y D R C N + C
Sbjct: 1663 -CYNTVGNYTCI---CPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Score = 68.2 bits (165), Expect = 3e-11
Identities = 45/118 (38%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Frame = +2
Query: 17 ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
+C GF + D+ C+DI+EC D C NT GSF+C C GF L CID
Sbjct: 1875 LCHTGFKTNDDQTMCLDINECERDACGNGT---CRNTIGSFNCRCNHGFIL-SHNNDCID 1930
Query: 194 VDECRI-NSDICPNRKFCINTPGNYSCIEPKCPDGYNF--DFRLKACLSNCTDKSPKC 358
VDEC N ++C N + CINT G++ C +C +GY D R ++ C + KC
Sbjct: 1931 VDECASGNGNLCRNGQ-CINTVGSFQC---QCNEGYEVAPDGRTCVDINECLLEPRKC 1984
Score = 67.0 bits (162), Expect = 6e-11
Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 4/134 (2%)
Frame = +2
Query: 62 DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DI+ECA D P C C N G++ C+C G+ + C+D++EC +NS +C N +
Sbjct: 723 DINECALD--PDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ 780
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLT---QASRIQYVVVQMTGS 409
C NTPG++ C CP G+ + LK C +S C+ + S ++ + S
Sbjct: 781 -CRNTPGSFVC---TCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSES 836
Query: 410 MAQPVEVRVINTMK 451
P + I T+K
Sbjct: 837 TLDPTKTICIETIK 850
Score = 66.6 bits (161), Expect = 8e-11
Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 2/120 (1%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
+C GF+ S D + C+D++EC D+ P C C NT GSF C C G++ C
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC--DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
D++EC I + C C NT G++ C C G+ D L C++ + C A
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKC---SCSPGWIGDGIKCTDLDECSNGTHMCSQHA 1378
Score = 65.5 bits (158), Expect = 2e-10
Identities = 34/88 (38%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Frame = +2
Query: 11 HEICKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
H +C GF + D + C D+DEC+ ++ C+N GSF C+C PGF L C
Sbjct: 554 HCVCNAGFHVTRDGKNCEDMDECS--IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSC 271
D++EC IC N + C+NT G+Y C
Sbjct: 612 KDINECE-TPGICMNGR-CVNTDGSYRC 637
Score = 65.1 bits (157), Expect = 2e-10
Identities = 36/102 (35%), Positives = 50/102 (49%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GF CID+DEC + G +C+N GS+ C C G+ +C D+D
Sbjct: 476 CNKGFQLDLRGECIDVDECEKNPCAGG---ECINNQGSYTCQCRAGYQSTLTRTECRDID 532
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
EC N IC N + CINT G++ C+ C G++ K C
Sbjct: 533 ECLQNGRICNNGR-CINTDGSFHCV---CNAGFHVTRDGKNC 570
Score = 63.2 bits (152), Expect = 9e-10
Identities = 39/112 (34%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Frame = +2
Query: 29 GFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECR 208
GF+ +G DIDEC + +CVN GS+HC+C G+T C+D++EC
Sbjct: 2395 GFMTNG----ADIDECKV-IHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC- 2448
Query: 209 INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
N P C NT G+Y C CP GY ++C L C K C
Sbjct: 2449 -NQAPKPCNFICKNTEGSYQC---SCPKGYILQEDGRSCKDLDECATKQHNC 2496
Score = 63.2 bits (152), Expect = 9e-10
Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
Frame = +2
Query: 20 CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C+ GF + C D+DEC + + CQ+ C N G + C CP G+ + + +C+D
Sbjct: 2552 CQRGFSLDQTGSSCEDVDECEGNHR---CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
+EC +++ IC C NT G+Y C+ CP G+ ++ C ++ C C
Sbjct: 2609 NEC-LSAHICGGAS-CHNTLGSYKCM---CPAGFQYEQFSGGCQDINECGSAQAPC 2659
Score = 62.8 bits (151), Expect = 1e-09
Identities = 43/116 (37%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C +GF+ S D + C DIDEC+ P C + C N G F C C G+ L C D
Sbjct: 1431 CDMGFVPSADGKACEDIDECSL---PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD 1487
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD-KSPKC 358
V+EC ++ C + C+NTPG+Y C CP DF L C D +S C
Sbjct: 1488 VNEC-LDPTTCISGN-CVNTPGSYIC---DCPP----DFELNPTRVGCVDTRSGNC 1534
Score = 61.2 bits (147), Expect = 4e-09
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
CK G+ ++ C D +EC P C + QC++T GSF+CLC GF C+D+
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEI--PNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDI 1892
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+EC D C N C NT G+++C +C G+
Sbjct: 1893 NEC--ERDACGNGT-CRNTIGSFNC---RCNHGF 1920
Score = 60.8 bits (146), Expect = 5e-09
Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
Frame = +2
Query: 17 ICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC G+ + S + C+DI+EC + C QC NT GSF C CP GF P C
Sbjct: 749 ICNSGYEVDSTGKNCVDINECVLNSL--LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806
Query: 191 DVDECRINSDICPNRKFCINTPGNYSC 271
D+DEC S C N C N+PG++ C
Sbjct: 807 DIDEC--ESSPCIN-GVCKNSPGSFIC 830
Score = 60.5 bits (145), Expect = 6e-09
Identities = 45/158 (28%), Positives = 62/158 (39%), Gaps = 48/158 (30%)
Frame = +2
Query: 29 GFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPK---------- 175
G I D +D+DEC +P C++ QC+NT GS+ C CP G+TL
Sbjct: 2116 GIIVGPDDSAVDMDECK---EPDVCKHGQCINTDGSYRCECPFGYTLAGNECVDTDECSV 2172
Query: 176 ----------------------------TMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
M C D++EC N +C R C+NT G+Y C
Sbjct: 2173 GNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYGSYEC 2230
Query: 272 IEPKCPDGYNFDFRLKACLS---------NCTDKSPKC 358
KCP GY + C +CT+K +C
Sbjct: 2231 ---KCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMEC 2265
Score = 60.1 bits (144), Expect = 8e-09
Identities = 33/81 (40%), Positives = 46/81 (56%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
C DIDEC + + + +C+NT GSFHC+C GF + C D+DEC I ++C N
Sbjct: 528 CRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR-NMCLN- 584
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
CIN G++ CI C G+
Sbjct: 585 GMCINEDGSFKCI---CKPGF 602
Score = 60.1 bits (144), Expect = 8e-09
Identities = 34/91 (37%), Positives = 43/91 (47%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
CID +EC +D+ + C NT GSF C C GF+L C DVDEC N +
Sbjct: 2522 CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRC---Q 2578
Query: 236 KFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
C N G Y C CP GY ++ C+
Sbjct: 2579 HGCQNIIGGYRC---SCPQGYLQHYQWNQCV 2606
Score = 57.4 bits (137), Expect = 5e-08
Identities = 43/131 (32%), Positives = 59/131 (45%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
+CK G+ G C D+DEC+ ++ QC+N G + C C GF C D+
Sbjct: 1390 LCKEGYTGDGFT-CTDLDECSENLNLCG-NGQCLNAPGGYRCECDMGFVPSADGKACEDI 1447
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
DEC + +IC C N PG + C +C GY D NCTD + +CL +
Sbjct: 1448 DECSL-PNICVFGT-CHNLPGLFRC---ECEIGYELD----RSGGNCTDVN-ECLDPTTC 1497
Query: 377 IQYVVVQMTGS 409
I V GS
Sbjct: 1498 ISGNCVNTPGS 1508
Score = 52.8 bits (125), Expect = 1e-06
Identities = 25/48 (52%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C DIDEC+T PG C+ +C NT S+ C CPPGF P +CIDV
Sbjct: 286 CEDIDECSTI--PGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331
Score = 51.2 bits (121), Expect = 4e-06
Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC G+ D GC+D +EC T KPG C+ +C+NT GS+ C C GFT P +C+
Sbjct: 2275 ICGPGYQRRPDGEGCVDENECQT--KPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2332
Query: 191 DVDECRINSDICPN 232
D E +++ N
Sbjct: 2333 DNREGYCFTEVLQN 2346
Score = 50.1 bits (118), Expect = 8e-06
Identities = 28/61 (45%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC G+ C DIDEC +V PG C+ CVNT GSF C CP G TL C+D
Sbjct: 895 ICGKGYSRIKGTQCEDIDEC--EVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Query: 194 V 196
+
Sbjct: 953 I 953
Score = 49.7 bits (117), Expect = 1e-05
Identities = 28/72 (38%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+IG+ G C D++EC + P +C CVNT GS+ C CPP F L P + C+D
Sbjct: 1472 CEIGYELDRSGGNCTDVNEC---LDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVD 1528
Query: 194 VDECRINSDICP 229
DI P
Sbjct: 1529 TRSGNCYLDIRP 1540
Score = 47.8 bits (112), Expect = 4e-05
Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +2
Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
+C+ T GS+ C C GF L + +CIDVDEC N C + CIN G+Y+C +C
Sbjct: 464 RCIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNP--CAGGE-CINNQGSYTC---QCR 516
Query: 290 DGYNFDFRLKAC--LSNCTDKSPKC 358
GY C + C C
Sbjct: 517 AGYQSTLTRTECRDIDECLQNGRIC 541
Score = 47.8 bits (112), Expect = 4e-05
Identities = 28/61 (45%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
ICK GF + D R C DI+EC T PG C +CVNT GS+ C C PG + C+
Sbjct: 597 ICKPGFQLASDGRYCKDINECET---PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653
Query: 191 D 193
D
Sbjct: 654 D 654
Score = 47.8 bits (112), Expect = 4e-05
Identities = 26/61 (42%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC G+ ++ C DIDEC + P C C NT GSF CLCP GF+L +C D
Sbjct: 1999 ICPPGYSLQNEK-CEDIDECVEE--PEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQD 2055
Query: 194 V 196
+
Sbjct: 2056 L 2056
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
Frame = +2
Query: 74 CATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECRINSDI 223
C ++ + + QC ++ G+ +C G++ T +C D+DEC + +
Sbjct: 862 CEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGT-QCEDIDECEVFPGV 920
Query: 224 CPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
C N C+NT G++ C +CP G D + CL
Sbjct: 921 CKN-GLCVNTRGSFKC---QCPSGMTLDATGRICL 951
Score = 44.3 bits (103), Expect = 4e-04
Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Frame = +2
Query: 17 ICKIGFIWSG-DRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGF 160
+C GF + GC DI+EC + P C Y C NT G + C CPPG+
Sbjct: 2632 MCPAGFQYEQFSGGCQDINECGSAQAP--CSYGCSNTEGGYLCGCPPGY 2678
Score = 43.5 bits (101), Expect = 8e-04
Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +2
Query: 116 VNTYGSFHCLCP--PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
VNT + LCP GF P T+ D+DEC+ +C K CINT G++ C +CP
Sbjct: 1580 VNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-CINTFGSFQC---RCP 1634
Query: 290 DGYNFDFRLKAC 325
GY + + C
Sbjct: 1635 TGYYLNEDTRVC 1646
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Frame = +2
Query: 101 CQYQCVNTYGSFHCLCP---PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
C+ + + F LC PGF + T +D+DECR +C N CIN G++ C
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRC 1791
Query: 272 IEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
+CP G+ ++ +L C + C P C A I
Sbjct: 1792 ---ECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECI 1825
>sp|P98133|FBN1_BOVIN Fibrillin-1 precursor (MP340)
Length = 2871
Score = 87.0 bits (214), Expect = 6e-17
Identities = 47/118 (39%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
Frame = +2
Query: 20 CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C G+ + DR C+DIDEC+ + G C+ C N+ GS+ C C PGF L P C D+
Sbjct: 1182 CNPGYHSTPDRLFCVDIDECS--IMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDI 1239
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSPK-CLT 364
DEC N +IC + C N PG Y C+ C DG+ +K C+ N D +P CL+
Sbjct: 1240 DECEDNPNICDGGQ-CTNIPGEYRCL---CYDGFMASEDMKTCVDVNECDLNPNICLS 1293
Score = 81.6 bits (200), Expect = 3e-15
Identities = 44/104 (42%), Positives = 59/104 (56%), Gaps = 1/104 (0%)
Frame = +2
Query: 35 IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRI 211
I +G R DI+EC + P C + +C NT GSF C C GF L + C D+DECRI
Sbjct: 1019 ITNGKRFFKDINECK--MIPNLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRI 1076
Query: 212 NSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
+ D+C R C+NTPG++ C KC +GY F + + NC D
Sbjct: 1077 SPDLC-GRGQCVNTPGDFEC---KCDEGYESGFMM---MKNCMD 1113
Score = 80.1 bits (196), Expect = 7e-15
Identities = 41/113 (36%), Positives = 56/113 (49%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GFI S + CID+DECAT QC+NT GSF C C G+ + P C+D++
Sbjct: 1916 CNHGFILSHNNDCIDVDECATGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDIN 1975
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
EC ++ C C N G+Y CI CP GY+ + C ++ C
Sbjct: 1976 ECLLDPRKCAPGT-CQNLDGSYRCI---CPPGYSLQNDKCEDIDECVEEPEIC 2024
Score = 77.0 bits (188), Expect = 6e-14
Identities = 51/163 (31%), Positives = 76/163 (46%), Gaps = 5/163 (3%)
Frame = +2
Query: 50 RGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
+ C+DIDEC D P C+ C+NT GS+ C CPPG L P CID++EC +++ +C
Sbjct: 1109 KNCMDIDECQRD--PLLCRGGVCLNTEGSYRCECPPGHQLAPNISACIDINECELSAHLC 1166
Query: 227 PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ--YVVV 394
P+ + C+N G Y C C GY+ C + C+ + C T + + Y
Sbjct: 1167 PHGR-CVNLIGKYQC---ACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECS 1222
Query: 395 QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
G P + R + + E+N + NIP Y L
Sbjct: 1223 CQPGFALMP-DQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264
Score = 75.9 bits (185), Expect = 1e-13
Identities = 48/129 (37%), Positives = 69/129 (53%), Gaps = 10/129 (7%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVK---PGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
C G+ + D R C+DI+EC D + PG+CQ N GS+ C+CPPG++L + KC
Sbjct: 1958 CNEGYEVAPDGRTCVDINECLLDPRKCAPGTCQ----NLDGSYRCICPPGYSL--QNDKC 2011
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC----LSNCTDK--S 349
D+DEC +IC C NT G++ C+ CPDG++ + C +S C K
Sbjct: 2012 EDIDECVEEPEICALGT-CSNTEGSFKCL---CPDGFSLSSTGRRCQDLRMSYCYAKFEG 2067
Query: 350 PKCLTQASR 376
KC + SR
Sbjct: 2068 GKCSSPKSR 2076
Score = 75.5 bits (184), Expect = 2e-13
Identities = 44/119 (36%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Frame = +2
Query: 11 HEICKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
H ICK G+ C+D++EC KP C + C NT GS+ C CP G+ L C
Sbjct: 2426 HCICKTGYTPDITGTACVDLNECNQAPKP--CNFICKNTEGSYQCSCPKGYILQEDGRSC 2483
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN--CTDKSPKC 358
D+DEC C + C+NT G+++C KCP G F AC+ N CT C
Sbjct: 2484 KDLDECATKQHNC--QFLCVNTIGSFTC---KCPPG--FTQHHTACIDNNECTSDINLC 2535
Score = 72.4 bits (176), Expect = 2e-12
Identities = 41/95 (43%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+ GFI + G C D+DEC PG CQ C+NT GSF C CP G + KC D
Sbjct: 231 CRRGFIPNIRTGACQDVDEC--QAIPGLCQGGNCINTVGSFECKCPAGHKFNEVSQKCED 288
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+DEC IC + C NT +Y C KCP G+
Sbjct: 289 IDECSTIPGICDGGE-CTNTVSSYFC---KCPPGF 319
Score = 72.0 bits (175), Expect = 2e-12
Identities = 37/83 (44%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
Frame = +2
Query: 59 IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
+DIDEC PG C+ C+N GSF C CP GF K + C D+DEC+ N +C
Sbjct: 1765 VDIDECREI--PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRN 1821
Query: 236 KFCINTPGNYSCIEPKCPDGYNF 304
CINT G+Y C C GY F
Sbjct: 1822 AECINTAGSYRC---DCKPGYRF 1841
Score = 70.1 bits (170), Expect = 8e-12
Identities = 38/102 (37%), Positives = 52/102 (50%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GF CID+DEC + G +C+NT GS+ C C PG+ +C D+D
Sbjct: 476 CNKGFQLDLRGECIDVDECEKNPCAGG---ECINTQGSYTCQCRPGYQSTLTRTECRDID 532
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
EC N IC N + CINT G++ C+ C G++ K C
Sbjct: 533 ECLQNGRICNNGR-CINTDGSFHCV---CNAGFHVTRDGKNC 570
Score = 70.1 bits (170), Expect = 8e-12
Identities = 38/94 (40%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C+ GF C DI+ECA + P C ++CVNTYGS+ C CP G+ L C D D
Sbjct: 2192 CEEGFEPGPMMTCEDINECAQN--PLLCAFRCVNTYGSYECKCPAGYVLREDRRMCKDED 2249
Query: 200 ECRINSDICPNRKF-CINTPGNYSCIEPKCPDGY 298
EC C ++ C N G Y CI C GY
Sbjct: 2250 ECEEGKHDCAEKQMECKNLIGTYLCI---CGPGY 2280
Score = 69.7 bits (169), Expect = 1e-11
Identities = 39/102 (38%), Positives = 52/102 (50%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C G+I G + C D+DEC+ S C NT GS+ CLC G+T C D+D
Sbjct: 1350 CSPGWIGDGIK-CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLD 1406
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
EC N ++C N + C+N PG Y C +C G+ KAC
Sbjct: 1407 ECSENLNLCGNGQ-CLNAPGGYRC---ECDMGFVPSADGKAC 1444
Score = 69.7 bits (169), Expect = 1e-11
Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DIDEC PG CQ +C+NT+GSF C CP G+ L T C DV+EC P
Sbjct: 1606 DIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT- 1662
Query: 239 FCINTPGNYSCIEPKCPDGYN--------FDFRLKACLSNCTDKSPKC 358
C NT GNY+CI CP Y D R C N + C
Sbjct: 1663 -CYNTVGNYTCI---CPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Score = 69.3 bits (168), Expect = 1e-11
Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKP-GSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C G++ DR C D DEC Q +C N G++ C+C PG+ P C+D
Sbjct: 2232 CPAGYVLREDRRMCKDEDECEEGKHDCAEKQMECKNLIGTYLCICGPGYQRRPDGEGCVD 2291
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
+EC+ IC N + C+NT G+Y+C +C DG+ CL N
Sbjct: 2292 ENECQTKPGICENGR-CLNTRGSYTC---ECNDGFTASPNQDECLDN 2334
Score = 68.2 bits (165), Expect = 3e-11
Identities = 45/118 (38%), Positives = 60/118 (50%), Gaps = 4/118 (3%)
Frame = +2
Query: 17 ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
+C GF + D+ C+DI+EC D C NT GSF+C C GF L CID
Sbjct: 1875 LCHTGFKTNADQTMCLDINECERDACGNGT---CRNTIGSFNCRCNHGFIL-SHNNDCID 1930
Query: 194 VDECRI-NSDICPNRKFCINTPGNYSCIEPKCPDGYNF--DFRLKACLSNCTDKSPKC 358
VDEC N ++C N + CINT G++ C +C +GY D R ++ C KC
Sbjct: 1931 VDECATGNGNLCRNGQ-CINTVGSFQC---QCNEGYEVAPDGRTCVDINECLLDPRKC 1984
Score = 67.8 bits (164), Expect = 4e-11
Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 4/134 (2%)
Frame = +2
Query: 62 DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DI+ECA D P C C N G++ C+C G+ + C+D++EC +NS +C N +
Sbjct: 723 DINECALD--PDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ 780
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLT---QASRIQYVVVQMTGS 409
C NTPG++ C CP G+ + LK C +S C+ + S ++ + S
Sbjct: 781 -CRNTPGSFVC---TCPKGFIYKPELKTCEDIDECESSPCINGVCKNSPGSFICECSSES 836
Query: 410 MAQPVEVRVINTMK 451
P + I T+K
Sbjct: 837 TLDPTKTICIETIK 850
Score = 67.0 bits (162), Expect = 6e-11
Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 2/120 (1%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
+C GF+ S D + C+D++EC D+ P C C NT GSF C C G++ C
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC--DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
D++EC I + C C NT G++ C C G+ D L C++ + C A
Sbjct: 1322 DINECEIGAHNCDRHAVCTNTAGSFKC---SCSPGWIGDGIKCTDLDECSNGTHMCSQHA 1378
Score = 65.1 bits (157), Expect = 2e-10
Identities = 34/88 (38%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Frame = +2
Query: 11 HEICKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
H +C GF + D + C D+DEC+ ++ C+N GSF C+C PGF L C
Sbjct: 554 HCVCNAGFHVTRDGKNCEDMDECS--IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSC 271
D++EC IC N + C+NT G+Y C
Sbjct: 612 KDINECE-TLGICMNGR-CVNTDGSYRC 637
Score = 63.9 bits (154), Expect = 5e-10
Identities = 43/116 (37%), Positives = 57/116 (49%), Gaps = 3/116 (2%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C +GF+ S D + C DIDEC+ P C + C N G F C C G+ L C D
Sbjct: 1431 CDMGFVPSADGKACEDIDECSL---PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD 1487
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD-KSPKC 358
V+EC ++ C + C+NTPG+Y+C CP DF L C D +S C
Sbjct: 1488 VNEC-LDPTTCISGN-CVNTPGSYTC---DCPP----DFELNPTRVGCVDTRSGNC 1534
Score = 63.5 bits (153), Expect = 7e-10
Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 2/129 (1%)
Frame = +2
Query: 29 GFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECR 208
GF+ +G DIDEC + +CVN GS+HC+C G+T C+D++EC
Sbjct: 2395 GFMTNG----ADIDECKV-IHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNEC- 2448
Query: 209 INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ 382
N P C NT G+Y C CP GY ++C L C K C Q
Sbjct: 2449 -NQAPKPCNFICKNTEGSYQC---SCPKGYILQEDGRSCKDLDECATKQHNC-------Q 2497
Query: 383 YVVVQMTGS 409
++ V GS
Sbjct: 2498 FLCVNTIGS 2506
Score = 63.2 bits (152), Expect = 9e-10
Identities = 35/91 (38%), Positives = 44/91 (48%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
CID +EC +D+ + C NT GSF C C GF+L P C DVDEC N +
Sbjct: 2522 CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDPTGASCEDVDECEGNHRC---Q 2578
Query: 236 KFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
C N G Y C CP GY ++ C+
Sbjct: 2579 HGCQNIIGGYRC---SCPQGYLQHYQWNQCV 2606
Score = 62.8 bits (151), Expect = 1e-09
Identities = 32/103 (31%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
C D+DEC + + CQ+ C N G + C CP G+ + + +C+D +EC +++ IC
Sbjct: 2565 CEDVDECEGNHR---CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGA 2620
Query: 236 KFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
C NT G+Y C+ CP G+ ++ C ++ C C
Sbjct: 2621 S-CHNTLGSYKCM---CPAGFQYEQFSGGCQDINECGSAQAPC 2659
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/87 (41%), Positives = 47/87 (54%), Gaps = 2/87 (2%)
Frame = +2
Query: 17 ICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC G+ + S + C+DI+EC + C QC NT GSF C CP GF P+ C
Sbjct: 749 ICNSGYEVDSTGKNCVDINECVLNSL--LCDNGQCRNTPGSFVCTCPKGFIYKPELKTCE 806
Query: 191 DVDECRINSDICPNRKFCINTPGNYSC 271
D+DEC S C N C N+PG++ C
Sbjct: 807 DIDEC--ESSPCIN-GVCKNSPGSFIC 830
Score = 61.2 bits (147), Expect = 4e-09
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
CK G+ ++ C D +EC P C + QC++T GSF+CLC GF C+D+
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEI--PNICSHGQCIDTVGSFYCLCHTGFKTNADQTMCLDI 1892
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+EC D C N C NT G+++C +C G+
Sbjct: 1893 NEC--ERDACGNGT-CRNTIGSFNC---RCNHGF 1920
Score = 60.1 bits (144), Expect = 8e-09
Identities = 33/81 (40%), Positives = 46/81 (56%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
C DIDEC + + + +C+NT GSFHC+C GF + C D+DEC I ++C N
Sbjct: 528 CRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR-NMCLN- 584
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
CIN G++ CI C G+
Sbjct: 585 GMCINEDGSFKCI---CKPGF 602
Score = 58.2 bits (139), Expect = 3e-08
Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Frame = +2
Query: 29 GFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDEC 205
G I D +D+DEC +P C++ QC+NT GS+ C CP G+ L + +C+D DEC
Sbjct: 2116 GIIVGPDDSAVDMDECK---EPDVCKHGQCINTDGSYRCECPFGYIL--QGNECVDTDEC 2170
Query: 206 RINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+ + C N C N G + C C +G+
Sbjct: 2171 SVGNP-CGNGT-CKNVIGGFEC---TCEEGF 2196
Score = 57.4 bits (137), Expect = 5e-08
Identities = 43/131 (32%), Positives = 59/131 (45%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
+CK G+ G C D+DEC+ ++ QC+N G + C C GF C D+
Sbjct: 1390 LCKEGYTGDGFT-CTDLDECSENLNLCG-NGQCLNAPGGYRCECDMGFVPSADGKACEDI 1447
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
DEC + +IC C N PG + C +C GY D NCTD + +CL +
Sbjct: 1448 DECSL-PNICVFGT-CHNLPGLFRC---ECEIGYELD----RSGGNCTDVN-ECLDPTTC 1497
Query: 377 IQYVVVQMTGS 409
I V GS
Sbjct: 1498 ISGNCVNTPGS 1508
Score = 52.0 bits (123), Expect = 2e-06
Identities = 25/48 (52%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C DIDEC+T PG C +C NT S+ C CPPGF P +CIDV
Sbjct: 286 CEDIDECSTI--PGICDGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331
Score = 51.6 bits (122), Expect = 3e-06
Identities = 59/229 (25%), Positives = 82/229 (35%), Gaps = 76/229 (33%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC G+ D GC+D +EC T KPG C+ +C+NT GS+ C C GFT P +C+
Sbjct: 2275 ICGPGYQRRPDGEGCVDENECQT--KPGICENGRCLNTRGSYTCECNDGFTASPNQDECL 2332
Query: 191 DVDE-----------CRINS-----------------------DICP------------- 229
D E C+I S +ICP
Sbjct: 2333 DNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPH 2392
Query: 230 NRKF---------------------CINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCT 340
R F C+N G+Y CI C GY D AC L+ C
Sbjct: 2393 GRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCI---CKTGYTPDITGTACVDLNECN 2449
Query: 341 DKSPKC--LTQASRIQYVVVQMTGSMAQP--VEVRVINTMKQKENNCQF 475
C + + + Y G + Q + ++ K++NCQF
Sbjct: 2450 QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF 2498
Score = 50.1 bits (118), Expect = 8e-06
Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
Frame = +2
Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
+C+ T GS+ C C GF L + +CIDVDEC N C + CINT G+Y+C +C
Sbjct: 464 RCIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNP--CAGGE-CINTQGSYTC---QCR 516
Query: 290 DGYNFDFRLKAC--LSNCTDKSPKC 358
GY C + C C
Sbjct: 517 PGYQSTLTRTECRDIDECLQNGRIC 541
Score = 50.1 bits (118), Expect = 8e-06
Identities = 28/72 (38%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+IG+ G C D++EC + P +C CVNT GS+ C CPP F L P + C+D
Sbjct: 1472 CEIGYELDRSGGNCTDVNEC---LDPTTCISGNCVNTPGSYTCDCPPDFELNPTRVGCVD 1528
Query: 194 VDECRINSDICP 229
DI P
Sbjct: 1529 TRSGNCYLDIRP 1540
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC G+ D+ C DIDEC + P C C NT GSF CLCP GF+L +C D
Sbjct: 1999 ICPPGYSLQNDK-CEDIDECVEE--PEICALGTCSNTEGSFKCLCPDGFSLSSTGRRCQD 2055
Query: 194 V 196
+
Sbjct: 2056 L 2056
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC G+ C DIDEC +V PG C+ CVN+ GSF C CP G TL C+D
Sbjct: 895 ICGKGYSRIKGTQCEDIDEC--EVFPGVCKNGLCVNSKGSFKCQCPSGMTLDATGRICLD 952
Query: 194 V 196
+
Sbjct: 953 I 953
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Frame = +2
Query: 41 SGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPP--------------GFTLYPKT 178
+GD C + E V SC +G+ LCPP GF P T
Sbjct: 1544 NGDTACSN--EIGVGVSKASCCCSLGKAWGTPCELCPPVNTSEYKILCPGGEGFRPNPIT 1601
Query: 179 MKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
+ D+DEC+ +C K CINT G++ C +CP GY + + C
Sbjct: 1602 VILEDIDECQELPGLCQGGK-CINTFGSFQC---RCPTGYYLNEDTRVC 1646
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Frame = +2
Query: 17 ICKIGFIWSG-DRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGF 160
+C GF + GC DI+EC + P C Y C NT G + C CPPG+
Sbjct: 2632 MCPAGFQYEQFSGGCQDINECGSAQAP--CSYGCSNTEGGYLCACPPGY 2678
Score = 44.3 bits (103), Expect = 4e-04
Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
Frame = +2
Query: 74 CATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECRINSDI 223
C ++ + + QC ++ G+ +C G++ T +C D+DEC + +
Sbjct: 862 CEININGATLKSQCCSSLGAAWGSPCTPCQVDPICGKGYSRIKGT-QCEDIDECEVFPGV 920
Query: 224 CPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
C N C+N+ G++ C +CP G D + CL
Sbjct: 921 CKN-GLCVNSKGSFKC---QCPSGMTLDATGRICL 951
Score = 43.9 bits (102), Expect = 6e-04
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
ICK GF + D R C DI+EC T G C +CVNT GS+ C C PG + C+
Sbjct: 597 ICKPGFQLASDGRYCKDINECET---LGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653
Query: 191 D 193
D
Sbjct: 654 D 654
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Frame = +2
Query: 101 CQYQCVNTYGSFHCLCP---PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
C+ + + F LC PGF + T +D+DECR +C N CIN G++ C
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRC 1791
Query: 272 IEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
+CP G+ ++ +L C + C P C A I
Sbjct: 1792 ---ECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECI 1825
>sp|Q08761|PROS_MOUSE Vitamin K-dependent protein S precursor
Length = 675
Score = 86.3 bits (212), Expect = 1e-16
Identities = 42/103 (40%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKP-GSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
CK G W GDR D++EC G C C NT GS+HC C GF + P C D+
Sbjct: 145 CKPG--WQGDRCQYDVNECKDPSNVNGGCSQICDNTPGSYHCSCKRGFAMLPNKKDCKDL 202
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
DEC + +C C N PG++ C +CPDGY +D K+C
Sbjct: 203 DECALKPSVC-GTAVCKNIPGDFEC---ECPDGYRYDPSSKSC 241
Score = 68.9 bits (167), Expect = 2e-11
Identities = 48/140 (34%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Frame = +2
Query: 11 HEICKIGF-IWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMK 184
H CK GF + + C D+DECA +KP C C N G F C CP G+ P +
Sbjct: 183 HCSCKRGFAMLPNKKDCKDLDECA--LKPSVCGTAVCKNIPGDFECECPDGYRYDPSSKS 240
Query: 185 CIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFR--------LKACLSNCT 340
C DVDEC + ++C + C+N PG YSC C F + CLS
Sbjct: 241 CKDVDEC--SENMC--AQLCVNFPGGYSCY---CDGKKGFKLAQDQKSCEGIPVCLSLDL 293
Query: 341 DKSPKCLTQASRIQYVVVQM 400
DK+ + L A + VV+ +
Sbjct: 294 DKNYELLYLAEQFAGVVLYL 313
>sp|Q9TV36|FBN1_PIG Fibrillin-1 precursor
Length = 2871
Score = 85.5 bits (210), Expect = 2e-16
Identities = 43/105 (40%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
C+DIDEC+ + G C+ C N+ GS+ C C PGF L P C D+DEC N +IC
Sbjct: 1195 CVDIDECS--IMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGG 1252
Query: 236 KFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSPK-CLT 364
+ C N PG Y C+ C DG+ +K C+ N D +P CL+
Sbjct: 1253 Q-CTNIPGEYRCL---CYDGFMASEDMKTCVDVNECDLNPNICLS 1293
Score = 81.6 bits (200), Expect = 3e-15
Identities = 42/95 (44%), Positives = 56/95 (58%), Gaps = 1/95 (1%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DI+EC + P C + +C NT GSF C C GF L + CID+DECRI+ D+C R
Sbjct: 1028 DINECK--MIPNLCTHGKCRNTIGSFKCRCDSGFALDSEERNCIDIDECRISPDLC-GRG 1084
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
C+NTPG++ C KC +GY F + + NC D
Sbjct: 1085 QCVNTPGDFEC---KCDEGYESGFMM---MKNCMD 1113
Score = 80.1 bits (196), Expect = 7e-15
Identities = 41/113 (36%), Positives = 55/113 (48%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GFI S + CID+DECAT QC+NT GSF C C G+ + P C+D++
Sbjct: 1916 CNHGFILSHNNDCIDVDECATGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDIN 1975
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
EC + C C N G+Y CI CP GY+ + C ++ C
Sbjct: 1976 ECLLEPGKCAPGT-CQNLDGSYRCI---CPPGYSLQNDKCEDIDECVEEPEIC 2024
Score = 75.9 bits (185), Expect = 1e-13
Identities = 43/106 (40%), Positives = 59/106 (55%), Gaps = 3/106 (2%)
Frame = +2
Query: 20 CKIGF-IWSGDRGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMK-CI 190
C GF + S +R CIDIDEC + P C + QCVNT G F C C G+ MK C+
Sbjct: 1055 CDSGFALDSEERNCIDIDECR--ISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCM 1112
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
D+DEC+ + +C C+NT G+Y C +CP G+ + AC+
Sbjct: 1113 DIDECQRDPLLC-RGGVCLNTEGSYRC---ECPSGHQMSPNISACI 1154
Score = 75.5 bits (184), Expect = 2e-13
Identities = 44/119 (36%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Frame = +2
Query: 11 HEICKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
H ICK G+ C+D++EC KP C + C NT GS+ C CP G+ L C
Sbjct: 2426 HCICKTGYTPDITGTACVDLNECNQAPKP--CNFICKNTEGSYQCSCPKGYILQEDGRSC 2483
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN--CTDKSPKC 358
D+DEC C + C+NT G+++C KCP G F AC+ N CT C
Sbjct: 2484 KDLDECATKQHNC--QFLCVNTIGSFAC---KCPPG--FTQHHTACIDNNECTSDINLC 2535
Score = 74.7 bits (182), Expect = 3e-13
Identities = 47/127 (37%), Positives = 68/127 (53%), Gaps = 8/127 (6%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C G+ + D R C+DI+EC ++PG C C N GS+ C+CPPG++L + KC D
Sbjct: 1958 CNEGYEVAPDGRTCVDINECL--LEPGKCAPGTCQNLDGSYRCICPPGYSL--QNDKCED 2013
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC----LSNCTDK--SPK 355
+DEC +IC C NT G++ C+ CPDG++ + C +S C K K
Sbjct: 2014 IDECVEEPEICALGT-CSNTEGSFKCL---CPDGFSLSSTGRRCQDLRMSYCYAKFEGGK 2069
Query: 356 CLTQASR 376
C + SR
Sbjct: 2070 CSSPKSR 2076
Score = 72.4 bits (176), Expect = 2e-12
Identities = 41/95 (43%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+ GFI + G C D+DEC PG CQ C+NT GSF C CP G + KC D
Sbjct: 231 CRRGFIPNIRTGACQDVDEC--QAIPGLCQGGNCINTVGSFECKCPAGHKFNEVSQKCED 288
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+DEC IC + C NT +Y C KCP G+
Sbjct: 289 IDECSTIPGICDGGE-CTNTVSSYFC---KCPPGF 319
Score = 72.0 bits (175), Expect = 2e-12
Identities = 37/83 (44%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
Frame = +2
Query: 59 IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
+DIDEC PG C+ C+N GSF C CP GF K + C D+DEC+ N +C
Sbjct: 1765 VDIDECREI--PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRN 1821
Query: 236 KFCINTPGNYSCIEPKCPDGYNF 304
CINT G+Y C C GY F
Sbjct: 1822 AECINTAGSYRC---DCKPGYRF 1841
Score = 69.7 bits (169), Expect = 1e-11
Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DIDEC PG CQ +C+NT+GSF C CP G+ L T C DV+EC P
Sbjct: 1606 DIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT- 1662
Query: 239 FCINTPGNYSCIEPKCPDGYN--------FDFRLKACLSNCTDKSPKC 358
C NT GNY+CI CP Y D R C N + C
Sbjct: 1663 -CYNTVGNYTCI---CPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Score = 69.3 bits (168), Expect = 1e-11
Identities = 38/94 (40%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C+ GF C DI+ECA + P C ++CVNTYGS+ C CP G+ L C D D
Sbjct: 2192 CEEGFEPGPMMTCEDINECAQN--PLLCAFRCVNTYGSYECKCPTGYVLREDRRMCKDED 2249
Query: 200 ECRINSDICPNRKF-CINTPGNYSCIEPKCPDGY 298
EC C ++ C N G Y CI C GY
Sbjct: 2250 ECEEGKHDCAEKQMECKNLIGMYICI---CGPGY 2280
Score = 68.9 bits (167), Expect = 2e-11
Identities = 45/118 (38%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Frame = +2
Query: 17 ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
+C GF + D+ C+DI+EC D C NT GSF+C C GF L CID
Sbjct: 1875 LCHTGFKTNADQTMCLDINECERDACGNGT---CRNTIGSFNCRCNHGFIL-SHNNDCID 1930
Query: 194 VDECRI-NSDICPNRKFCINTPGNYSCIEPKCPDGYNF--DFRLKACLSNCTDKSPKC 358
VDEC N ++C N + CINT G++ C +C +GY D R ++ C + KC
Sbjct: 1931 VDECATGNGNLCRNGQ-CINTVGSFQC---QCNEGYEVAPDGRTCVDINECLLEPGKC 1984
Score = 68.2 bits (165), Expect = 3e-11
Identities = 37/102 (36%), Positives = 51/102 (50%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GF CID+DEC + G +C+N GS+ C C PG+ +C D+D
Sbjct: 476 CNKGFQLDLRGECIDVDECEKNPCAGG---ECINNQGSYTCQCRPGYQSTLTRTECRDID 532
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
EC N IC N + CINT G++ C+ C G++ K C
Sbjct: 533 ECLQNGRICNNGR-CINTDGSFHCV---CNAGFHVTRDGKNC 570
Score = 68.2 bits (165), Expect = 3e-11
Identities = 37/107 (34%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKP-GSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C G++ DR C D DEC Q +C N G + C+C PG+ P C+D
Sbjct: 2232 CPTGYVLREDRRMCKDEDECEEGKHDCAEKQMECKNLIGMYICICGPGYQRRPDGEGCVD 2291
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
+EC+ IC N + C+NT G+Y+C +C DG+ CL N
Sbjct: 2292 ENECQTKPGICENGR-CLNTRGSYTC---ECNDGFTASPTQDECLDN 2334
Score = 67.4 bits (163), Expect = 5e-11
Identities = 35/88 (39%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
Frame = +2
Query: 11 HEICKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
H +C GF + D + C D+DEC+ ++ C+N GSF C+C PGF L C
Sbjct: 554 HCVCNAGFHVTRDGKNCEDMDECS--IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSC 271
D++EC S IC N + C+NT G+Y C
Sbjct: 612 KDINECE-TSGICMNGR-CVNTDGSYRC 637
Score = 67.4 bits (163), Expect = 5e-11
Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 2/120 (1%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
+C GF+ S D + C+D++EC D+ P C C NT GSF C C G++ C
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC--DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
D++EC I + C C NT G+++C C G+ D L C++ + C A
Sbjct: 1322 DINECEIGAHNCDRHAVCTNTAGSFNC---SCSPGWIGDGIKCTDLDECSNGTHMCSQHA 1378
Score = 67.0 bits (162), Expect = 6e-11
Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 4/134 (2%)
Frame = +2
Query: 62 DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DI+ECA D P C C N G++ C+C G+ + C+D++EC +NS +C N +
Sbjct: 723 DINECALD--PDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ 780
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLT---QASRIQYVVVQMTGS 409
C NTPG++ C CP G+ + LK C +S C+ + S ++ + S
Sbjct: 781 -CRNTPGSFVC---TCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSES 836
Query: 410 MAQPVEVRVINTMK 451
P + I T+K
Sbjct: 837 TLDPTKTICIETIK 850
Score = 67.0 bits (162), Expect = 6e-11
Identities = 30/73 (41%), Positives = 45/73 (61%), Gaps = 1/73 (1%)
Frame = +2
Query: 50 RGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
+ C+DIDEC D P C+ C+NT GS+ C CP G + P CID++EC +++ +C
Sbjct: 1109 KNCMDIDECQRD--PLLCRGGVCLNTEGSYRCECPSGHQMSPNISACIDINECELSAHLC 1166
Query: 227 PNRKFCINTPGNY 265
P+ + C+N G Y
Sbjct: 1167 PHGR-CVNLIGKY 1178
Score = 65.9 bits (159), Expect = 1e-10
Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQ-YQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+ GF D R C DIDEC + P C QC N G + CLC GF C+D
Sbjct: 1223 CQPGFALMPDQRSCTDIDEC--EDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVD 1280
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
V+EC +N +IC + C NT G++ C C GY+ K + CTD
Sbjct: 1281 VNECDLNPNICLSGT-CENTKGSFIC---HCDMGYSG----KKGKTGCTD 1322
Score = 65.1 bits (157), Expect = 2e-10
Identities = 40/113 (35%), Positives = 53/113 (46%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C G+I G + C D+DEC+ S C NT GS+ CLC G+T C D+D
Sbjct: 1350 CSPGWIGDGIK-CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCADLD 1406
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
EC N +C N + C+ PG Y C Y+ F A +C D S +C
Sbjct: 1407 ECSENVKLCGNVQ-CLYAPGGYHC-------EYDMGFVPSADRKSCVD-SDEC 1450
Score = 64.7 bits (156), Expect = 3e-10
Identities = 43/131 (32%), Positives = 59/131 (45%), Gaps = 2/131 (1%)
Frame = +2
Query: 29 GFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECR 208
GF+ +G DIDEC + +C+N GS+HC+C G+T C+D++EC
Sbjct: 2395 GFMTNG----ADIDECKV-IHDVCRNGECINDRGSYHCICKTGYTPDITGTACVDLNEC- 2448
Query: 209 INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRIQ 382
N P C NT G+Y C CP GY ++C L C K C Q
Sbjct: 2449 -NQAPKPCNFICKNTEGSYQC---SCPKGYILQEDGRSCKDLDECATKQHNC-------Q 2497
Query: 383 YVVVQMTGSMA 415
++ V GS A
Sbjct: 2498 FLCVNTIGSFA 2508
Score = 64.3 bits (155), Expect = 4e-10
Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
Frame = +2
Query: 20 CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C+ GF + C D+DEC + + CQ+ C N G + C CP G+ + + +C+D
Sbjct: 2552 CQRGFSLDQSGASCEDVDECEGNHR---CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
+EC +++ IC C NT G+Y C+ CP G+ ++ C ++ C C
Sbjct: 2609 NEC-LSAHICGGAS-CHNTLGSYKCM---CPAGFQYEQFSGGCQDINECGSSQAPC 2659
Score = 63.2 bits (152), Expect = 9e-10
Identities = 42/114 (36%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Frame = +2
Query: 26 IGFIWSGDR-GCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
+GF+ S DR C+D DEC+ P C + C N G F C C G+ L C DV+
Sbjct: 1433 MGFVPSADRKSCVDSDECSL---PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVN 1489
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD-KSPKC 358
EC + C + C+NTPG+Y+C+ CP DF L C D +S C
Sbjct: 1490 EC-LEPPTCISGN-CVNTPGSYTCV---CPP----DFELNPTRVGCVDTRSGNC 1534
Score = 61.2 bits (147), Expect = 4e-09
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
CK G+ ++ C D +EC P C + QC++T GSF+CLC GF C+D+
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEI--PNICSHGQCIDTVGSFYCLCHTGFKTNADQTMCLDI 1892
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+EC D C N C NT G+++C +C G+
Sbjct: 1893 NEC--ERDACGNGT-CRNTIGSFNC---RCNHGF 1920
Score = 60.8 bits (146), Expect = 5e-09
Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
Frame = +2
Query: 17 ICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC G+ + S + C+DI+EC + C QC NT GSF C CP GF P C
Sbjct: 749 ICNSGYEVDSTGKNCVDINECVLNSL--LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806
Query: 191 DVDECRINSDICPNRKFCINTPGNYSC 271
D+DEC S C N C N+PG++ C
Sbjct: 807 DIDEC--ESSPCIN-GVCKNSPGSFIC 830
Score = 60.8 bits (146), Expect = 5e-09
Identities = 34/91 (37%), Positives = 43/91 (47%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
CID +EC +D+ + C NT GSF C C GF+L C DVDEC N +
Sbjct: 2522 CIDNNECTSDINLCGAKGICQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRC---Q 2578
Query: 236 KFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
C N G Y C CP GY ++ C+
Sbjct: 2579 HGCQNIIGGYRC---SCPQGYLQHYQWNQCV 2606
Score = 60.1 bits (144), Expect = 8e-09
Identities = 33/81 (40%), Positives = 46/81 (56%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
C DIDEC + + + +C+NT GSFHC+C GF + C D+DEC I ++C N
Sbjct: 528 CRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR-NMCLN- 584
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
CIN G++ CI C G+
Sbjct: 585 GMCINEDGSFKCI---CKPGF 602
Score = 58.2 bits (139), Expect = 3e-08
Identities = 49/169 (28%), Positives = 75/169 (44%), Gaps = 8/169 (4%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPN 232
CIDI+EC ++ C + +CVN G + PG+ P + C+D+DEC I + C
Sbjct: 1153 CIDINEC--ELSAHLCPHGRCVNLIGKYQRARNPGYHSTPDRLFCVDIDECSIMNGGC-- 1208
Query: 233 RKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC-LTQASRI--QYVVVQ 397
FC N+ G+Y C C G+ ++C + C D C Q + I +Y +
Sbjct: 1209 ETFCTNSEGSYEC---SCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLC 1265
Query: 398 MTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPI--TYESLQGSII 538
G MA + + E D+ PNI + T E+ +GS I
Sbjct: 1266 YDGFMAS----------EDMKTCVDVNECDLNPNICLSGTCENTKGSFI 1304
Score = 58.2 bits (139), Expect = 3e-08
Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Frame = +2
Query: 29 GFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDEC 205
G I D +D+DEC +P C++ QC+NT GS+ C CP G+ L + +C+D DEC
Sbjct: 2116 GIIVGPDDSAVDMDECK---EPDVCKHGQCINTDGSYRCECPFGYIL--EGNECVDTDEC 2170
Query: 206 RINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+ + C N C N G + C C +G+
Sbjct: 2171 SVGNP-CGNGT-CKNVIGGFEC---TCEEGF 2196
Score = 57.8 bits (138), Expect = 4e-08
Identities = 44/131 (33%), Positives = 59/131 (45%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
+CK G+ G C D+DEC+ +VK QC+ G +HC GF C+D
Sbjct: 1390 LCKEGYTGDGFT-CADLDECSENVKLCG-NVQCLYAPGGYHCEYDMGFVPSADRKSCVDS 1447
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
DEC + +IC C N PG + C +C GY D NCTD + +CL +
Sbjct: 1448 DECSL-PNICVFGT-CHNLPGLFRC---ECEIGYELD----RSGGNCTDVN-ECLEPPTC 1497
Query: 377 IQYVVVQMTGS 409
I V GS
Sbjct: 1498 ISGNCVNTPGS 1508
Score = 52.4 bits (124), Expect = 2e-06
Identities = 27/72 (37%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+IG+ G C D++EC ++P +C CVNT GS+ C+CPP F L P + C+D
Sbjct: 1472 CEIGYELDRSGGNCTDVNEC---LEPPTCISGNCVNTPGSYTCVCPPDFELNPTRVGCVD 1528
Query: 194 VDECRINSDICP 229
D+ P
Sbjct: 1529 TRSGNCYLDVRP 1540
Score = 52.0 bits (123), Expect = 2e-06
Identities = 25/48 (52%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C DIDEC+T PG C +C NT S+ C CPPGF P +CIDV
Sbjct: 286 CEDIDECSTI--PGICDGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331
Score = 51.6 bits (122), Expect = 3e-06
Identities = 60/229 (26%), Positives = 82/229 (35%), Gaps = 76/229 (33%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC G+ D GC+D +EC T KPG C+ +C+NT GS+ C C GFT P +C+
Sbjct: 2275 ICGPGYQRRPDGEGCVDENECQT--KPGICENGRCLNTRGSYTCECNDGFTASPTQDECL 2332
Query: 191 DVDE-----------CRINS-----------------------DICP------------- 229
D E C+I S +ICP
Sbjct: 2333 DNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPH 2392
Query: 230 NRKF---------------------CINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCT 340
R F CIN G+Y CI C GY D AC L+ C
Sbjct: 2393 GRGFMTNGADIDECKVIHDVCRNGECINDRGSYHCI---CKTGYTPDITGTACVDLNECN 2449
Query: 341 DKSPKC--LTQASRIQYVVVQMTGSMAQP--VEVRVINTMKQKENNCQF 475
C + + + Y G + Q + ++ K++NCQF
Sbjct: 2450 QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF 2498
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC G+ D+ C DIDEC + P C C NT GSF CLCP GF+L +C D
Sbjct: 1999 ICPPGYSLQNDK-CEDIDECVEE--PEICALGTCSNTEGSFKCLCPDGFSLSSTGRRCQD 2055
Query: 194 V 196
+
Sbjct: 2056 L 2056
Score = 48.1 bits (113), Expect = 3e-05
Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +2
Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
+C+ T GS+ C C GF L + +CIDVDEC N C + CIN G+Y+C +C
Sbjct: 464 RCIPTPGSYRCECNKGFQLDLRG-ECIDVDECEKNP--CAGGE-CINNQGSYTC---QCR 516
Query: 290 DGYNFDFRLKAC--LSNCTDKSPKC 358
GY C + C C
Sbjct: 517 PGYQSTLTRTECRDIDECLQNGRIC 541
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC G+ C DIDEC +V PG C+ CVN+ GSF C CP G TL C+D
Sbjct: 895 ICGKGYSRIKGTQCEDIDEC--EVFPGVCKNGLCVNSKGSFKCQCPNGMTLDATGRICLD 952
Query: 194 V 196
+
Sbjct: 953 I 953
Score = 45.1 bits (105), Expect = 3e-04
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
ICK GF + D R C DI+EC T G C +CVNT GS+ C C PG + C+
Sbjct: 597 ICKPGFQLASDGRYCKDINECETS---GICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653
Query: 191 D 193
D
Sbjct: 654 D 654
Score = 45.1 bits (105), Expect = 3e-04
Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Frame = +2
Query: 17 ICKIGFIWSG-DRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGF 160
+C GF + GC DI+EC + P C Y C NT G + C CPPG+
Sbjct: 2632 MCPAGFQYEQFSGGCQDINECGSSQAP--CSYGCSNTEGGYLCGCPPGY 2678
Score = 44.7 bits (104), Expect = 3e-04
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 10/95 (10%)
Frame = +2
Query: 74 CATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECRINSDI 223
C ++ + + QC ++ G+ +C G++ T +C D+DEC + +
Sbjct: 862 CEININGATLKSQCCSSLGAAWGSPCTPCQVDPICGKGYSRIKGT-QCEDIDECEVFPGV 920
Query: 224 CPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
C N C+N+ G++ C +CP+G D + CL
Sbjct: 921 CKN-GLCVNSKGSFKC---QCPNGMTLDATGRICL 951
Score = 43.9 bits (102), Expect = 6e-04
Identities = 29/76 (38%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Frame = +2
Query: 110 QC--VNTYGSFHCLCP--PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIE 277
QC VNT + LCP GF P T+ D+DEC+ +C K CINT G++ C
Sbjct: 1576 QCPPVNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-CINTFGSFQC-- 1631
Query: 278 PKCPDGYNFDFRLKAC 325
+CP GY + + C
Sbjct: 1632 -RCPTGYYLNEDTRVC 1646
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Frame = +2
Query: 101 CQYQCVNTYGSFHCLCP---PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
C+ + + F LC PGF + T +D+DECR +C N CIN G++ C
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRC 1791
Query: 272 IEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
+CP G+ ++ +L C + C P C A I
Sbjct: 1792 ---ECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECI 1825
>sp|Q61554|FBN1_MOUSE Fibrillin-1 precursor
Length = 2871
Score = 85.1 bits (209), Expect = 2e-16
Identities = 46/118 (38%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
Frame = +2
Query: 20 CKIGFIWSGDR-GCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C G+ + DR C+DIDEC+ + G C+ C N+ GS+ C C PGF L P C D+
Sbjct: 1182 CNPGYHPTHDRLFCVDIDECS--IMNGGCETFCTNSDGSYECSCQPGFALMPDQRSCTDI 1239
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLS-NCTDKSPK-CLT 364
D+C N +IC + C N PG Y C+ C DG+ +K C+ N D +P CL+
Sbjct: 1240 DQCEDNPNICDGGQ-CTNIPGEYRCL---CYDGFMASEDMKTCVDVNECDLNPNICLS 1293
Score = 80.5 bits (197), Expect = 6e-15
Identities = 42/113 (37%), Positives = 56/113 (49%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GFI S + CID+DECAT QCVNT GSF C C G+ + P C+D++
Sbjct: 1916 CNHGFILSHNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDIN 1975
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKC 358
EC ++ C C N G+Y CI CP GY+ + C ++ C
Sbjct: 1976 ECVLDPGKCAPGT-CQNLDGSYRCI---CPPGYSLQNDKCEDIDECVEEPEIC 2024
Score = 79.7 bits (195), Expect = 1e-14
Identities = 41/95 (43%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DI+EC + P C + +C NT GSF C C GF L + C D+DECRI+ D+C R
Sbjct: 1028 DINECK--MIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC-GRG 1084
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD 343
C+NTPG++ C KC +GY F + + NC D
Sbjct: 1085 QCVNTPGDFEC---KCDEGYESGFMM---MKNCMD 1113
Score = 75.9 bits (185), Expect = 1e-13
Identities = 51/163 (31%), Positives = 75/163 (46%), Gaps = 5/163 (3%)
Frame = +2
Query: 50 RGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDIC 226
+ C+DIDEC D P C+ C NT G++ C CPPG L P CID++EC +++++C
Sbjct: 1109 KNCMDIDECQRD--PLLCRGGICHNTEGTYRCECPPGHQLSPNISACIDINECELSANLC 1166
Query: 227 PNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI--QYVVV 394
P+ + C+N G Y C C GY+ C + C+ + C T + Y
Sbjct: 1167 PHGR-CVNLIGKYQC---ACNPGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECS 1222
Query: 395 QMTGSMAQPVEVRVINTMKQKENNCQFTEKDVTPNIPITYESL 523
G P + R + Q E+N + NIP Y L
Sbjct: 1223 CQPGFALMP-DQRSCTDIDQCEDNPNICDGGQCTNIPGEYRCL 1264
Score = 75.1 bits (183), Expect = 2e-13
Identities = 47/127 (37%), Positives = 68/127 (53%), Gaps = 8/127 (6%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C G+ + D R C+DI+EC D PG C C N GS+ C+CPPG++L + KC D
Sbjct: 1958 CNEGYEVAPDGRTCVDINECVLD--PGKCAPGTCQNLDGSYRCICPPGYSL--QNDKCED 2013
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC----LSNCTDK--SPK 355
+DEC +IC C NT G++ C+ CP+G+++ + C +S C K K
Sbjct: 2014 IDECVEEPEICALGT-CSNTEGSFKCL---CPEGFSWSSSGRRCQDLRMSYCYAKFEGGK 2069
Query: 356 CLTQASR 376
C + SR
Sbjct: 2070 CSSPKSR 2076
Score = 74.7 bits (182), Expect = 3e-13
Identities = 44/119 (36%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
Frame = +2
Query: 11 HEICKIGFIWS-GDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKC 187
H ICK G+ C+D++EC KP C + C NT GS+ C CP G+ L C
Sbjct: 2426 HCICKTGYTPDITGTSCVDLNECNQAPKP--CNFICKNTEGSYQCSCPNGYILQEDGRSC 2483
Query: 188 IDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN--CTDKSPKC 358
D+DEC C + C+NT G ++C KCP G F AC+ N CT C
Sbjct: 2484 KDLDECATKQHNC--QFLCVNTIGGFTC---KCPPG--FTQHHTACIDNNECTSDINLC 2535
Score = 72.4 bits (176), Expect = 2e-12
Identities = 40/95 (42%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+ GFI + G C D+DEC PG CQ C+NT GSF C CP G + KC D
Sbjct: 231 CRRGFIPNIRTGACQDVDEC--QAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQKCED 288
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+DEC +C + C NT +Y C KCP G+
Sbjct: 289 IDECSTIPGVCDGGE-CTNTVSSYFC---KCPPGF 319
Score = 72.0 bits (175), Expect = 2e-12
Identities = 39/107 (36%), Positives = 56/107 (52%), Gaps = 2/107 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGS-CQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C +G++ DR C D DECA + Q +C N G++ C+C PG+ P CID
Sbjct: 2232 CPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCID 2291
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSN 334
+EC+ IC N + C+NT G+Y+C +C DG+ CL N
Sbjct: 2292 ENECQTKPGICENGR-CLNTLGSYTC---ECNDGFTASPTQDECLDN 2334
Score = 71.6 bits (174), Expect = 3e-12
Identities = 42/106 (39%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Frame = +2
Query: 20 CKIGF-IWSGDRGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMK-CI 190
C GF + S +R C DIDEC + P C + QCVNT G F C C G+ MK C+
Sbjct: 1055 CDSGFALDSEERNCTDIDECR--ISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCM 1112
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
D+DEC+ + +C C NT G Y C +CP G+ + AC+
Sbjct: 1113 DIDECQRDPLLC-RGGICHNTEGTYRC---ECPPGHQLSPNISACI 1154
Score = 69.7 bits (169), Expect = 1e-11
Identities = 39/102 (38%), Positives = 52/102 (50%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C G+I G + C D+DEC+ S C NT GS+ CLC G+T C D+D
Sbjct: 1350 CSPGWIGDGIK-CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGYT--GDGFTCTDLD 1406
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
EC N ++C N + C+N PG Y C +C G+ KAC
Sbjct: 1407 ECSENLNLCGNGQ-CLNAPGGYRC---ECDMGFVPSADGKAC 1444
Score = 69.7 bits (169), Expect = 1e-11
Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 9/108 (8%)
Frame = +2
Query: 62 DIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DIDEC PG CQ +C+NT+GSF C CP G+ L T C DV+EC P
Sbjct: 1606 DIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT- 1662
Query: 239 FCINTPGNYSCIEPKCPDGYN--------FDFRLKACLSNCTDKSPKC 358
C NT GNY+CI CP Y D R C N + C
Sbjct: 1663 -CYNTVGNYTCI---CPPDYMQVNGGNNCMDMRRSICYRNYYADNQTC 1706
Score = 69.7 bits (169), Expect = 1e-11
Identities = 38/94 (40%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C+ GF C DI+ECA + P C ++CVNTYGS+ C CP G+ L C D D
Sbjct: 2192 CEEGFEPGPMMTCEDINECAQN--PLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDED 2249
Query: 200 ECRINSDICPNRKF-CINTPGNYSCIEPKCPDGY 298
EC C ++ C N G Y CI C GY
Sbjct: 2250 ECAEGKHDCTEKQMECKNLIGTYMCI---CGPGY 2280
Score = 68.9 bits (167), Expect = 2e-11
Identities = 37/89 (41%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
Frame = +2
Query: 11 HEICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMK 184
H +C GF + S + C D+DEC T P C C+N GSF C+C PGF L
Sbjct: 554 HCVCNAGFHVSSEGKNCEDMDECRT---PNMCPNGMCINEDGSFKCICKPGFQLASDGRY 610
Query: 185 CIDVDECRINSDICPNRKFCINTPGNYSC 271
C D++EC IC N + C+NT G+Y C
Sbjct: 611 CKDINECE-TPGICMNGR-CVNTDGSYRC 637
Score = 68.9 bits (167), Expect = 2e-11
Identities = 36/81 (44%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +2
Query: 59 IDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
+DIDEC PG C+ C+N GSF C CP GF K + C D+DEC+ N +C
Sbjct: 1765 VDIDECREI--PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCLRN 1821
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
CINT G+Y C C GY
Sbjct: 1822 AECINTAGSYRC---DCKPGY 1839
Score = 67.8 bits (164), Expect = 4e-11
Identities = 44/118 (37%), Positives = 60/118 (50%), Gaps = 4/118 (3%)
Frame = +2
Query: 17 ICKIGFIWSGDRG-CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
+C GF + D+ C+DI+EC D C NT GSF+C C GF L CID
Sbjct: 1875 LCHTGFKTNEDQTMCLDINECERDACGNGT---CRNTIGSFNCRCNHGFIL-SHNNDCID 1930
Query: 194 VDECRI-NSDICPNRKFCINTPGNYSCIEPKCPDGYNF--DFRLKACLSNCTDKSPKC 358
VDEC N ++C N + C+NT G++ C +C +GY D R ++ C KC
Sbjct: 1931 VDECATGNGNLCRNGQ-CVNTVGSFQC---RCNEGYEVAPDGRTCVDINECVLDPGKC 1984
Score = 66.6 bits (161), Expect = 8e-11
Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 2/120 (1%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
+C GF+ S D + C+D++EC D+ P C C NT GSF C C G++ C
Sbjct: 1264 LCYDGFMASEDMKTCVDVNEC--DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQA 370
D++EC I + C C NT G++ C C G+ D L C++ + C A
Sbjct: 1322 DINECEIGAHNCGRHAVCTNTAGSFKC---SCSPGWIGDGIKCTDLDECSNGTHMCSQHA 1378
Score = 66.2 bits (160), Expect = 1e-10
Identities = 36/102 (35%), Positives = 50/102 (49%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVD 199
C GF CID+DEC + G +C+N GS+ C C G+ +C D+D
Sbjct: 476 CNKGFQLDIRGECIDVDECEKNPCTGG---ECINNQGSYTCHCRAGYQSTLTRTECRDID 532
Query: 200 ECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC 325
EC N IC N + CINT G++ C+ C G++ K C
Sbjct: 533 ECLQNGRICNNGR-CINTDGSFHCV---CNAGFHVSSEGKNC 570
Score = 65.5 bits (158), Expect = 2e-10
Identities = 34/81 (41%), Positives = 48/81 (59%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
C DIDEC + + + +C+NT GSFHC+C GF + + C D+DECR ++CPN
Sbjct: 528 CRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVSSEGKNCEDMDECR-TPNMCPN- 584
Query: 236 KFCINTPGNYSCIEPKCPDGY 298
CIN G++ CI C G+
Sbjct: 585 GMCINEDGSFKCI---CKPGF 602
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 1/101 (0%)
Frame = +2
Query: 62 DIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRK 238
DI+ECA D P C C N G++ C+C G+ + C+D++EC +NS +C N +
Sbjct: 723 DINECALD--PDICPNGICENLRGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQ 780
Query: 239 FCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCL 361
C NTPG++ C CP G+ + LK C +S C+
Sbjct: 781 -CRNTPGSFVC---TCPKGFVYKPDLKTCEDIDECESSPCI 817
Score = 63.9 bits (154), Expect = 5e-10
Identities = 34/116 (29%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
Frame = +2
Query: 20 CKIGF-IWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C+ GF + C D+DEC + + CQ+ C N G + C CP G+ + + +C+D
Sbjct: 2552 CQRGFSLDQSGASCEDVDECEGNHR---CQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
+EC +++ +C C NT G+Y C+ CP G+ ++ C ++ C C
Sbjct: 2609 NEC-LSAHVCGGAS-CHNTLGSYKCM---CPAGFQYEQFSGGCQDINECGSSQAPC 2659
Score = 63.5 bits (153), Expect = 7e-10
Identities = 38/112 (33%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
Frame = +2
Query: 29 GFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECR 208
GF+ +G D+DEC + +CVN GS+HC+C G+T C+D++EC
Sbjct: 2395 GFMTNG----ADVDECKV-IHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC- 2448
Query: 209 INSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKSPKC 358
N P C NT G+Y C CP+GY ++C L C K C
Sbjct: 2449 -NQAPKPCNFICKNTEGSYQC---SCPNGYILQEDGRSCKDLDECATKQHNC 2496
Score = 60.8 bits (146), Expect = 5e-09
Identities = 42/116 (36%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C +GF+ S D + C DIDEC+ P C + C N G F C C G+ L C D
Sbjct: 1431 CDMGFVPSADGKACEDIDECSL---PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD 1487
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTD-KSPKC 358
V+EC ++ C + C+NTPG+Y+C C DF L C D +S C
Sbjct: 1488 VNEC-LDPTTCISGN-CVNTPGSYTC---DCSP----DFELNPTRVGCVDTRSGNC 1534
Score = 60.5 bits (145), Expect = 6e-09
Identities = 34/91 (37%), Positives = 43/91 (47%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNR 235
CID +EC +D+ + C NT GSF C C GF+L C DVDEC N +
Sbjct: 2522 CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRC---Q 2578
Query: 236 KFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
C N G Y C CP GY ++ C+
Sbjct: 2579 HGCQNIIGGYRC---SCPQGYLQHYQWNQCV 2606
Score = 60.1 bits (144), Expect = 8e-09
Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Frame = +2
Query: 20 CKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
CK G+ + C D +EC P C + QC++T GSF+CLC GF C+D+
Sbjct: 1835 CKPGYRLTSTGQCNDRNECQEI--PNICSHGQCIDTVGSFYCLCHTGFKTNEDQTMCLDI 1892
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
+EC D C N C NT G+++C +C G+
Sbjct: 1893 NEC--ERDACGNGT-CRNTIGSFNC---RCNHGF 1920
Score = 58.9 bits (141), Expect = 2e-08
Identities = 35/87 (40%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Frame = +2
Query: 17 ICKIGF-IWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC G+ + + C+DI+EC + C QC NT GSF C CP GF P C
Sbjct: 749 ICNSGYEVDITGKNCVDINECVLNSL--LCDNGQCRNTPGSFVCTCPKGFVYKPDLKTCE 806
Query: 191 DVDECRINSDICPNRKFCINTPGNYSC 271
D+DEC S C N C N+PG++ C
Sbjct: 807 DIDEC--ESSPCIN-GVCKNSPGSFIC 830
Score = 58.5 bits (140), Expect = 2e-08
Identities = 35/98 (35%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
Frame = +2
Query: 14 EICKIG--FIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMK 184
+IC G I D +D+DEC +P C++ QC+NT GS+ C CP G+ L + +
Sbjct: 2109 QICPFGSGIIVGPDDSAVDMDECK---EPDVCRHGQCINTDGSYRCECPFGYIL--EGNE 2163
Query: 185 CIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGY 298
C+D DEC + + C N C N G + C C +G+
Sbjct: 2164 CVDTDECSVGNP-CGNGT-CKNVIGGFEC---TCEEGF 2196
Score = 57.4 bits (137), Expect = 5e-08
Identities = 43/131 (32%), Positives = 59/131 (45%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
+CK G+ G C D+DEC+ ++ QC+N G + C C GF C D+
Sbjct: 1390 LCKDGYTGDGFT-CTDLDECSENLNLCG-NGQCLNAPGGYRCECDMGFVPSADGKACEDI 1447
Query: 197 DECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACLSNCTDKSPKCLTQASR 376
DEC + +IC C N PG + C +C GY D NCTD + +CL +
Sbjct: 1448 DECSL-PNICVFGT-CHNLPGLFRC---ECEIGYELD----RSGGNCTDVN-ECLDPTTC 1497
Query: 377 IQYVVVQMTGS 409
I V GS
Sbjct: 1498 ISGNCVNTPGS 1508
Score = 56.2 bits (134), Expect = 1e-07
Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Frame = +2
Query: 20 CKIGFIWSGDR-GCIDIDECATDVKPGSC--QYQCVNTYGSFHCLCPPGFTLYPKTMKCI 190
C +GF ++ C DIDEC C +C+NT GS+ C C PG+ L T +C
Sbjct: 1793 CPVGFFYNDKLLVCEDIDECQNGPV---CLRNAECINTAGSYRCDCKPGYRL-TSTGQCN 1848
Query: 191 DVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
D +EC+ +IC + + CI+T G++ C+ C G+ + CL
Sbjct: 1849 DRNECQEIPNICSHGQ-CIDTVGSFYCL---CHTGFKTNEDQTMCL 1890
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/74 (41%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
IC G+ D GCID +EC T KPG C+ +C+NT GS+ C C GFT P +C+
Sbjct: 2275 ICGPGYQRRPDGEGCIDENECQT--KPGICENGRCLNTLGSYTCECNDGFTASPTQDECL 2332
Query: 191 DVDECRINSDICPN 232
D E S++ N
Sbjct: 2333 DNREGYCFSEVFEN 2346
Score = 51.6 bits (122), Expect = 3e-06
Identities = 24/48 (50%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 56 CIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C DIDEC+T PG C +C NT S+ C CPPGF P +C+DV
Sbjct: 286 CEDIDECSTI--PGVCDGGECTNTVSSYFCKCPPGFYTSPDGTRCVDV 331
Score = 47.4 bits (111), Expect = 5e-05
Identities = 28/61 (45%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Frame = +2
Query: 17 ICKIGFIWSGD-RGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCI 190
ICK GF + D R C DI+EC T PG C +CVNT GS+ C C PG + C+
Sbjct: 597 ICKPGFQLASDGRYCKDINECET---PGICMNGRCVNTDGSYRCECFPGLAVGLDGRWCV 653
Query: 191 D 193
D
Sbjct: 654 D 654
Score = 47.0 bits (110), Expect = 7e-05
Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = +2
Query: 110 QCVNTYGSFHCLCPPGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
+C+ T GS+ C C GF L + +CIDVDEC N C + CIN G+Y+C C
Sbjct: 464 RCIPTPGSYRCECNKGFQLDIRG-ECIDVDECEKNP--CTGGE-CINNQGSYTC---HCR 516
Query: 290 DGYNFDFRLKAC--LSNCTDKSPKC 358
GY C + C C
Sbjct: 517 AGYQSTLTRTECRDIDECLQNGRIC 541
Score = 47.0 bits (110), Expect = 7e-05
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC GF C DI+EC +V PG C+ CVN+ GSF C CP G TL C+D
Sbjct: 895 ICGKGFSRIKGTQCEDINEC--EVFPGVCKNGLCVNSRGSFKCECPNGMTLDATGRICLD 952
Query: 194 V 196
+
Sbjct: 953 I 953
Score = 47.0 bits (110), Expect = 7e-05
Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVKPGSCQY-QCVNTYGSFHCLCPPGFTLYPKTMKCID 193
IC G+ D+ C DIDEC + P C C NT GSF CLCP GF+ +C D
Sbjct: 1999 ICPPGYSLQNDK-CEDIDECVEE--PEICALGTCSNTEGSFKCLCPEGFSWSSSGRRCQD 2055
Query: 194 V 196
+
Sbjct: 2056 L 2056
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/69 (37%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
Frame = +2
Query: 20 CKIGFIWSGDRG-CIDIDECATDVKPGSC-QYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
C+IG+ G C D++EC + P +C CVNT GS+ C C P F L P + C+D
Sbjct: 1472 CEIGYELDRSGGNCTDVNEC---LDPTTCISGNCVNTPGSYTCDCSPDFELNPTRVGCVD 1528
Query: 194 V--DECRIN 214
C +N
Sbjct: 1529 TRSGNCYLN 1537
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
Frame = +2
Query: 101 CQYQCVNTYGSFHCLCP---PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSC 271
C+ + + F LC PGF + T +D+DECR +C N CIN G++ C
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRC 1791
Query: 272 IEPKCPDGYNFDFRLKAC--LSNCTDKSPKCLTQASRI 379
+CP G+ ++ +L C + C P CL A I
Sbjct: 1792 ---ECPVGFFYNDKLLVCEDIDEC-QNGPVCLRNAECI 1825
Score = 45.1 bits (105), Expect = 3e-04
Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Frame = +2
Query: 17 ICKIGFIWSG-DRGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGF 160
+C GF + GC DI+EC + P C Y C NT G + C CPPG+
Sbjct: 2632 MCPAGFQYEQFSGGCQDINECGSSQAP--CSYGCSNTEGGYLCGCPPGY 2678
Score = 43.5 bits (101), Expect = 8e-04
Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +2
Query: 116 VNTYGSFHCLCP--PGFTLYPKTMKCIDVDECRINSDICPNRKFCINTPGNYSCIEPKCP 289
VNT + LCP GF P T+ D+DEC+ +C K CINT G++ C +CP
Sbjct: 1580 VNT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-CINTFGSFQC---RCP 1634
Query: 290 DGYNFDFRLKAC 325
GY + + C
Sbjct: 1635 TGYYLNEDTRVC 1646
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 10/95 (10%)
Frame = +2
Query: 74 CATDVKPGSCQYQCVNTYGS----------FHCLCPPGFTLYPKTMKCIDVDECRINSDI 223
C ++ + + +C ++ G+ +C GF+ T +C D++EC + +
Sbjct: 862 CEININGATLKSECCSSLGAAWGSPCTICQLDPICGKGFSRIKGT-QCEDINECEVFPGV 920
Query: 224 CPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKACL 328
C N C+N+ G++ C +CP+G D + CL
Sbjct: 921 CKN-GLCVNSRGSFKC---ECPNGMTLDATGRICL 951
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 19/113 (16%)
Frame = +2
Query: 20 CKIGFIWSGD-RGCIDIDECATDVKPGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCIDV 196
C GF++ D + C DIDEC + C N+ GSF C C P TL P CI+
Sbjct: 792 CPKGFVYKPDLKTCEDIDECESSPCINGV---CKNSPGSFICECSPESTLDPTKTICIET 848
Query: 197 -----------DECRIN-------SDICPNRKFCINTPGNYSCIEPKCPDGYN 301
C IN S+ C + +P ++P C G++
Sbjct: 849 IKGTCWQTVIDGRCEININGATLKSECCSSLGAAWGSPCTICQLDPICGKGFS 901
>sp|P53813|PROS_RAT Vitamin K-dependent protein S precursor
Length = 675
Score = 84.3 bits (207), Expect = 4e-16
Identities = 43/114 (37%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Frame = +2
Query: 17 ICKIGFIWSGDRGCIDIDECATDVK-PGSCQYQCVNTYGSFHCLCPPGFTLYPKTMKCID 193
ICK G W GD+ DI+EC G C C NT GS+HC C GF + C D
Sbjct: 144 ICKPG--WQGDKCQFDINECKDPSNINGGCSQTCDNTPGSYHCSCKIGFAMLTNKKDCKD 201
Query: 194 VDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFRLKAC--LSNCTDKS 349
VDEC + +C C N PG++ C +CP+GY +D K+C + C++ +
Sbjct: 202 VDECSLKPSVC-GTAVCKNIPGDFEC---ECPNGYRYDPSSKSCKDVDECSENT 251
Score = 71.2 bits (173), Expect = 3e-12
Identities = 49/140 (35%), Positives = 66/140 (47%), Gaps = 10/140 (7%)
Frame = +2
Query: 11 HEICKIGF-IWSGDRGCIDIDECATDVKPGSCQYQ-CVNTYGSFHCLCPPGFTLYPKTMK 184
H CKIGF + + + C D+DEC+ +KP C C N G F C CP G+ P +
Sbjct: 183 HCSCKIGFAMLTNKKDCKDVDECS--LKPSVCGTAVCKNIPGDFECECPNGYRYDPSSKS 240
Query: 185 CIDVDECRINSDICPNRKFCINTPGNYSCIEPKCPDGYNFDFR--------LKACLSNCT 340
C DVDEC N+ C + C+N PG YSC C F + CLS
Sbjct: 241 CKDVDECSENT--CA--QLCVNYPGGYSCY---CDGKKGFKLAQDQRSCEGIPVCLSLDL 293
Query: 341 DKSPKCLTQASRIQYVVVQM 400
DK+ + L A + VV+ +
Sbjct: 294 DKNYELLYLAEQFAGVVLYL 313
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,630,126
Number of Sequences: 369166
Number of extensions: 2205884
Number of successful extensions: 7931
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4787
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6496
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8598109270
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)