Planaria EST Database


DrC_02900

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02900
         (928 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9UNI6|DUS12_HUMAN  Dual specificity protein phosphatase ...   153   6e-37
sp|Q9D0T2|DUS12_MOUSE  Dual specificity protein phosphatase ...   147   4e-35
sp|Q02256|PVH1_YEAST  Tyrosine-protein phosphatase YVH1 (PTP...   103   7e-22
sp|Q16690|DUS5_HUMAN  Dual specificity protein phosphatase 5...    88   3e-17
sp|O54838|DUS5_RAT  Dual specificity protein phosphatase 5 (...    86   1e-16
sp|Q16828|DUS6_HUMAN  Dual specificity protein phosphatase 6...    75   3e-13
sp|Q64346|DUS6_RAT  Dual specificity protein phosphatase 6 (...    75   3e-13
sp|Q9DBB1|DUS6_MOUSE  Dual specificity protein phosphatase 6...    75   3e-13
sp|Q16829|DUS7_HUMAN  Dual specificity protein phosphatase 7...    73   1e-12
sp|Q63340|DUS7_RAT  Dual specificity protein phosphatase 7 (...    73   1e-12
>sp|Q9UNI6|DUS12_HUMAN Dual specificity protein phosphatase 12 (Dual-specificity tyrosine
           phosphatase YVH1)
          Length = 340

 Score =  153 bits (387), Expect = 6e-37
 Identities = 103/285 (36%), Positives = 150/285 (52%), Gaps = 33/285 (11%)
 Frame = +1

Query: 10  LKSLHIKSILTVMDTPLEHKI-----DLFQYKFIKAYDVLDQDLISHFDDACEFIDKGRE 174
           L+   I ++LTV       K      DL++  F+ A D  + DL+SH D    FI + R 
Sbjct: 48  LREAGITAVLTVDSEEPSFKAGPGVEDLWRL-FVPALDKPETDLLSHLDRCVAFIGQARA 106

Query: 175 KG--VLVHCLAGISRSGTIMTAYLMKTLQIDPNEAIAKIKE-KSYICPNDGFKQQLKMYY 345
           +G  VLVHC AG+SRS  I+TA+LMKT Q+   +A  K++  K     N+GF+ QLK+Y 
Sbjct: 107 EGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQ 166

Query: 346 NMKYCGQYKSDEYKQF-VQICQRDDIDVCNVVSKMPTTPKSTV-----DPVQYKCRKCRA 507
            M Y     S  YKQ+ +Q       ++ N+  ++     +TV     D V YKCRKCR 
Sbjct: 167 AMGYEVDTSSAIYKQYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRR 226

Query: 508 MLFDNTNLVEH-----------------SKLNSENTICTEEVFIEALSWIDSS--NVTGG 630
            LF ++++++H                 S L +         FIE + W++S+   V  G
Sbjct: 227 SLFRSSSILDHREGSGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDG 286

Query: 631 KINCPKCHSKLGSYTWVGERCVCGNWVVPAFHIAKQKVDSVKSNP 765
           ++ CPKC +KLGS+ W GE+C CG W+ PAF I K +VD +K  P
Sbjct: 287 QLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEMKILP 331
>sp|Q9D0T2|DUS12_MOUSE Dual specificity protein phosphatase 12 (Dual specificity
           phosphatase T-DSP4) (Dual specificity phosphatase VH1)
          Length = 339

 Score =  147 bits (371), Expect = 4e-35
 Identities = 90/255 (35%), Positives = 140/255 (54%), Gaps = 30/255 (11%)
 Frame = +1

Query: 91  FIKAYDVLDQDLISHFDDACEFIDKGREKG--VLVHCLAGISRSGTIMTAYLMKTLQIDP 264
           F+ A D  + DL+SH D    FI + R +G  VLVHC AG+SRS  ++ A++MKT Q+  
Sbjct: 78  FVPALDKPETDLLSHLDRCVAFIGQARSEGRAVLVHCHAGVSRSVAVVMAFIMKTDQLTF 137

Query: 265 NEA---IAKIKEKSYICPNDGFKQQLKMYYNMKYCGQYKSDEYKQF-VQICQRDDIDVCN 432
            +A   +  +K ++ +  N+GF+ QLK+Y  M Y     S  YKQ+ +Q        + N
Sbjct: 138 EKAYDILRTVKPEAKV--NEGFEWQLKLYEAMGYEVDTSSAFYKQYRLQKVTEKCPKLWN 195

Query: 433 VVSKMPTTPKSTV-----DPVQYKCRKCRAMLFDNTNLVEHS----------KLNSENTI 567
           +  ++     +T+     D + YKCRKCR  LF +++++ HS          K  + +++
Sbjct: 196 LPQELFAVDPTTISQGLKDDILYKCRKCRRSLFRHSSILGHSEGSGPIAFAHKRTAPSSV 255

Query: 568 CTE-------EVFIEALSWIDSS--NVTGGKINCPKCHSKLGSYTWVGERCVCGNWVVPA 720
            T          FIE + W++S+   V  G++ CPKC +KLGS+ W GE+C CG W+ PA
Sbjct: 256 LTTGSQAQCTSYFIEPVQWMESTLLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPA 315

Query: 721 FHIAKQKVDSVKSNP 765
           F I K +VD +K  P
Sbjct: 316 FQIHKNRVDEMKMLP 330
>sp|Q02256|PVH1_YEAST Tyrosine-protein phosphatase YVH1 (PTPase YVH1)
          Length = 364

 Score =  103 bits (257), Expect = 7e-22
 Identities = 79/271 (29%), Positives = 112/271 (41%), Gaps = 62/271 (22%)
 Frame = +1

Query: 121 DLISHFDDACEFID-------------------KGREKGVLVHCLAGISRSGTIMTAYLM 243
           D++ +FD+   FID                   K +   V  HC AG+SRS T + AYLM
Sbjct: 74  DVLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLM 133

Query: 244 KTLQIDPNEAIAKIKEKS-YICPNDGFKQQLKMYYNMKYC------GQYKSDEYKQFVQI 402
               +  + A+  +K K   + PN+ F +QL ++  M           YK  + KQ +++
Sbjct: 134 YRYGLSLSMAMHAVKRKKPSVEPNENFMEQLHLFEKMGGDFVDFDNPAYKQWKLKQSIKL 193

Query: 403 CQRDDIDVCNV-----------VSKMPTTPKSTVDPVQYKCRKCRAMLFDNTNLVEHSK- 546
                  V N            + K+    KS V  V  +C+KCR  L  +T+ + H   
Sbjct: 194 DPSGSELVSNSGMFKDSESSQDLDKLTEAEKSKVTAV--RCKKCRTKLALSTSFIAHDPP 251

Query: 547 -------------LNSENTICTEE-------VFIEALSW----IDSSNVTGGKINCPKCH 654
                         NS   I  +E        FIE L W    +       GK +CP C 
Sbjct: 252 SKESSEGHFIKRAANSHRIIDIQESQANCSHFFIEPLKWMQPELQGKQELEGKFSCPGCS 311

Query: 655 SKLGSYTWVGERCVCGNWVVPAFHIAKQKVD 747
           SK+G Y W G RC CG WV+PA H+   KVD
Sbjct: 312 SKVGGYNWKGSRCSCGKWVIPAIHLQTSKVD 342
>sp|Q16690|DUS5_HUMAN Dual specificity protein phosphatase 5 (Dual specificity protein
           phosphatase hVH3)
          Length = 384

 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 56/116 (48%), Positives = 67/116 (57%), Gaps = 3/116 (2%)
 Frame = +1

Query: 4   ELLKSLHIKSILTVMDTPLEHKIDLFQYKFIKAYDVLDQDLISHFDDACEFIDKGREKG- 180
           E L +LHI ++L V     E  +    YK+I   D    D+ SHF +A +FID  REKG 
Sbjct: 198 EFLANLHITALLNVSRRTSEACMTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGG 257

Query: 181 -VLVHCLAGISRSGTIMTAYLMKTLQIDPNEAIAKIKE-KSYICPNDGFKQQLKMY 342
            VLVHC AGISRS TI  AYLMKT Q    EA   IK+ +S + PN GF  QL  Y
Sbjct: 258 KVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQY 313
>sp|O54838|DUS5_RAT Dual specificity protein phosphatase 5 (MAP-kinase phosphatase
           CPG21)
          Length = 384

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 54/116 (46%), Positives = 66/116 (56%), Gaps = 3/116 (2%)
 Frame = +1

Query: 4   ELLKSLHIKSILTVMDTPLEHKIDLFQYKFIKAYDVLDQDLISHFDDACEFIDKGREKG- 180
           E L +LHI ++L V     E       YK+I   D    D+ SHF +A +FID  RE+G 
Sbjct: 198 EFLANLHITALLNVSRRTSEACTTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREEGG 257

Query: 181 -VLVHCLAGISRSGTIMTAYLMKTLQIDPNEAIAKIKE-KSYICPNDGFKQQLKMY 342
            VLVHC AG+SRS TI  AYLMKT Q    EA   IK+ +S + PN GF  QL  Y
Sbjct: 258 KVLVHCEAGVSRSPTICMAYLMKTKQFRLKEAFEYIKQRRSVVSPNFGFMGQLLQY 313
>sp|Q16828|DUS6_HUMAN Dual specificity protein phosphatase 6 (Mitogen-activated protein
           kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
           (Dual specificity protein phosphatase PYST1)
          Length = 381

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 53/118 (44%), Positives = 67/118 (56%), Gaps = 7/118 (5%)
 Frame = +1

Query: 1   IELLKSLHIKSILTVMDTP----LEHKIDLFQYKFIKAYDVLDQDLISHFDDACEFIDKG 168
           +++L+   IK IL V  TP    L      F+YK I   D   Q+L   F +A  FID+ 
Sbjct: 225 LDVLEEFGIKYILNV--TPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEA 282

Query: 169 REK--GVLVHCLAGISRSGTIMTAYLMKTLQIDPNEAIAKIK-EKSYICPNDGFKQQL 333
           R K  GVLVHCLAGISRS T+  AYLM+ L +  N+A   +K +KS I PN  F  QL
Sbjct: 283 RGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340
>sp|Q64346|DUS6_RAT Dual specificity protein phosphatase 6 (Mitogen-activated protein
           kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
          Length = 381

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 53/118 (44%), Positives = 67/118 (56%), Gaps = 7/118 (5%)
 Frame = +1

Query: 1   IELLKSLHIKSILTVMDTP----LEHKIDLFQYKFIKAYDVLDQDLISHFDDACEFIDKG 168
           +++L+   IK IL V  TP    L      F+YK I   D   Q+L   F +A  FID+ 
Sbjct: 225 LDVLEEFGIKYILNV--TPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEA 282

Query: 169 REK--GVLVHCLAGISRSGTIMTAYLMKTLQIDPNEAIAKIK-EKSYICPNDGFKQQL 333
           R K  GVLVHCLAGISRS T+  AYLM+ L +  N+A   +K +KS I PN  F  QL
Sbjct: 283 RGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340
>sp|Q9DBB1|DUS6_MOUSE Dual specificity protein phosphatase 6 (Mitogen-activated protein
           kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
          Length = 381

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 53/118 (44%), Positives = 67/118 (56%), Gaps = 7/118 (5%)
 Frame = +1

Query: 1   IELLKSLHIKSILTVMDTP----LEHKIDLFQYKFIKAYDVLDQDLISHFDDACEFIDKG 168
           +++L+   IK IL V  TP    L      F+YK I   D   Q+L   F +A  FID+ 
Sbjct: 225 LDVLEEFGIKYILNV--TPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEA 282

Query: 169 REK--GVLVHCLAGISRSGTIMTAYLMKTLQIDPNEAIAKIK-EKSYICPNDGFKQQL 333
           R K  GVLVHCLAGISRS T+  AYLM+ L +  N+A   +K +KS I PN  F  QL
Sbjct: 283 RGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340
>sp|Q16829|DUS7_HUMAN Dual specificity protein phosphatase 7 (Dual specificity protein
           phosphatase PYST2)
          Length = 368

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 51/117 (43%), Positives = 66/117 (56%), Gaps = 6/117 (5%)
 Frame = +1

Query: 1   IELLKSLHIKSILTV---MDTPLEHKIDLFQYKFIKAYDVLDQDLISHFDDACEFIDKGR 171
           +++L    IK IL V   +    EH  + F YK I   D   Q+L   F +A  FID+ R
Sbjct: 212 LDVLGKYGIKYILNVTPNLPNAFEHGGE-FTYKQIPISDHWSQNLSQFFPEAISFIDEAR 270

Query: 172 EK--GVLVHCLAGISRSGTIMTAYLMKTLQIDPNEAIAKIK-EKSYICPNDGFKQQL 333
            K  GVLVHCLAGISRS T+  AYLM+ + +  N+A   +K +KS I PN  F  QL
Sbjct: 271 SKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQL 327
>sp|Q63340|DUS7_RAT Dual specificity protein phosphatase 7 (Dual specificity protein
           phosphatase MKP-X)
          Length = 280

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 51/117 (43%), Positives = 66/117 (56%), Gaps = 6/117 (5%)
 Frame = +1

Query: 1   IELLKSLHIKSILTV---MDTPLEHKIDLFQYKFIKAYDVLDQDLISHFDDACEFIDKGR 171
           +++L    IK IL V   +    EH  + F YK I   D   Q+L   F +A  FID+ R
Sbjct: 124 LDVLGKYGIKYILNVTPNLPNAFEHGGE-FTYKQIPISDHWSQNLSQFFPEAISFIDEAR 182

Query: 172 EK--GVLVHCLAGISRSGTIMTAYLMKTLQIDPNEAIAKIK-EKSYICPNDGFKQQL 333
            K  GVLVHCLAGISRS T+  AYLM+ + +  N+A   +K +KS I PN  F  QL
Sbjct: 183 SKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQL 239
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105,785,066
Number of Sequences: 369166
Number of extensions: 2238109
Number of successful extensions: 7145
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6125
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7036
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9510757740
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)