Planaria EST Database


DrC_02868

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02868
         (558 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q16611|BAK_HUMAN  Bcl-2 homologous antagonist/killer (Apo...    68   2e-11
sp|Q13014|BAK2_HUMAN  Putative Bcl-2 homologous antagonist/k...    67   3e-11
sp|O08734|BAK_MOUSE  Bcl-2 homologous antagonist/killer (Apo...    66   7e-11
sp|Q91827|AR1_XENLA  Apoptosis regulator R1 (XR1)                  61   2e-09
sp|Q91828|AR11_XENLA  Apoptosis regulator R11 (XR11)               50   4e-06
sp|Q92843|BCLW_HUMAN  Apoptosis regulator Bcl-W (Bcl-2-like ...    47   3e-05
sp|P70345|BCLW_MOUSE  Apoptosis regulator Bcl-W (Bcl-2-like ...    46   5e-05
sp|P53563|BCLX_RAT  Apoptosis regulator Bcl-X (Bcl-2-like 1 ...    45   2e-04
sp|Q64373|BCLX_MOUSE  Apoptosis regulator Bcl-X (Bcl-2-like ...    45   2e-04
sp|Q07817|BCLX_HUMAN  Apoptosis regulator Bcl-X (Bcl-2-like ...    44   2e-04
>sp|Q16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK)
           (Bcl-2-like 7 protein)
          Length = 211

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 46/148 (31%), Positives = 75/148 (50%), Gaps = 1/148 (0%)
 Frame = +2

Query: 14  PENKDSVSWQIGKKLASIADKLALDESSKGLIKEIVTLV-NVGPDDSGAFKEFSEIAKKV 190
           P    S   Q+G++LA I D +     ++    E  T++ ++ P    A++ F++IA  +
Sbjct: 64  PLQPSSTMGQVGRQLAIIGDDI-----NRRYDSEFQTMLQHLQPTAENAYEYFTKIATSL 118

Query: 191 IEGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLGIFKWIISNGGWR 370
            E GI+W  V  L  FGYR+A      G+  FL Q+ ++++D      I +WI   GGW 
Sbjct: 119 FESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWV 178

Query: 371 DFLGNDSDDGNVYSALVYPSVVVGVVAL 454
             L  +  +G + + L    VV+GVV L
Sbjct: 179 AAL--NLGNGPILNVL----VVLGVVLL 200
>sp|Q13014|BAK2_HUMAN Putative Bcl-2 homologous antagonist/killer 2 (Apoptosis regulator
           BAK-2)
          Length = 211

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 45/148 (30%), Positives = 75/148 (50%), Gaps = 1/148 (0%)
 Frame = +2

Query: 14  PENKDSVSWQIGKKLASIADKLALDESSKGLIKEIVTLV-NVGPDDSGAFKEFSEIAKKV 190
           P    S   Q+G++LA I D +     ++    E  T++ ++ P    A++ F++IA  +
Sbjct: 64  PLQPSSTMGQVGRQLAIIGDDI-----NRRYDSEFQTMLQHLQPTAENAYEYFTKIASSL 118

Query: 191 IEGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLGIFKWIISNGGWR 370
            E GI+W  V  L  F YR+A     +G+  FL Q+ ++++D      I +WI   GGW 
Sbjct: 119 FESGINWGRVVALLGFSYRLALHIYQRGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWV 178

Query: 371 DFLGNDSDDGNVYSALVYPSVVVGVVAL 454
             L  +  +G + + L    VV+GVV L
Sbjct: 179 AAL--NLGNGPILNVL----VVLGVVLL 200
>sp|O08734|BAK_MOUSE Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK)
          Length = 208

 Score = 65.9 bits (159), Expect = 7e-11
 Identities = 38/124 (30%), Positives = 64/124 (51%), Gaps = 2/124 (1%)
 Frame = +2

Query: 2   LPHAPENKDSVSWQIGKKLASIADKL--ALDESSKGLIKEIVTLVNVGPDDSGAFKEFSE 175
           + + P   +S+  Q+G++LA I D +    D   + L++++       P    A++ F++
Sbjct: 57  MDNLPLEPNSILGQVGRQLALIGDDINRRYDTEFQNLLEQLQ------PTAGNAYELFTK 110

Query: 176 IAKKVIEGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLGIFKWIIS 355
           IA  + + GISW  V  L  FGYR+A     +G+  FL Q+  ++ DI     I +WI  
Sbjct: 111 IASSLFKSGISWGRVVALLGFGYRLALYVYQRGLTGFLGQVTCFLADIILHHYIARWIAQ 170

Query: 356 NGGW 367
            GGW
Sbjct: 171 RGGW 174
>sp|Q91827|AR1_XENLA Apoptosis regulator R1 (XR1)
          Length = 228

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 32/122 (26%), Positives = 59/122 (48%)
 Frame = +2

Query: 14  PENKDSVSWQIGKKLASIADKLALDESSKGLIKEIVTLVNVGPDDSGAFKEFSEIAKKVI 193
           PE   + S  +   + +  D+   +E  +    EI T ++V P    A+  F+E+A  + 
Sbjct: 67  PEPSGAASCALHSAMRAAGDEF--EERFRQAFSEISTQIHVTPGT--AYARFAEVAGSLF 122

Query: 194 EGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLGIFKWIISNGGWRD 373
           +GG++W  +   F FG  +  + + K +   L ++  W++   +   +  WI SNGGW  
Sbjct: 123 QGGVNWGRIVAFFVFGAALCAESVNKEMSPLLPRIQDWMVTYLE-TNLRDWIQSNGGWNG 181

Query: 374 FL 379
           FL
Sbjct: 182 FL 183
>sp|Q91828|AR11_XENLA Apoptosis regulator R11 (XR11)
          Length = 204

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 25/111 (22%), Positives = 51/111 (45%), Gaps = 8/111 (7%)
 Frame = +2

Query: 155 AFKEFSEIAKKVIEGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLG 334
           A + F ++  ++   G +W  +   F FG  +  +   K +   L +++QW+++  +   
Sbjct: 91  AQQSFQQVMGELFRDGTNWGRIVAFFSFGRALCVESANKEMTDLLPRIVQWMVNYLEHT- 149

Query: 335 IFKWIISNGGWRDFLG--------NDSDDGNVYSALVYPSVVVGVVALICY 463
           +  W+  NGGW  F+G           +    +  L+   ++ GV AL+CY
Sbjct: 150 LQPWMQENGGWEAFVGLYGKNAAAQSRESQERFGRLLTIVMLTGVFALVCY 200
>sp|Q92843|BCLW_HUMAN Apoptosis regulator Bcl-W (Bcl-2-like 2 protein)
          Length = 193

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 18/74 (24%), Positives = 42/74 (56%)
 Frame = +2

Query: 155 AFKEFSEIAKKVIEGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLG 334
           A + F++++ ++ +GG +W  +   F FG  +  + + K ++  + Q+ +W++  +    
Sbjct: 75  AQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMV-AYLETR 133

Query: 335 IFKWIISNGGWRDF 376
           +  WI S+GGW +F
Sbjct: 134 LADWIHSSGGWAEF 147
>sp|P70345|BCLW_MOUSE Apoptosis regulator Bcl-W (Bcl-2-like 2 protein) (c98)
          Length = 193

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 18/74 (24%), Positives = 41/74 (55%)
 Frame = +2

Query: 155 AFKEFSEIAKKVIEGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLG 334
           A + F++++ ++ +GG +W  +   F FG  +  + + K ++  + Q+  W++  +    
Sbjct: 75  AQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQDWMV-AYLETR 133

Query: 335 IFKWIISNGGWRDF 376
           +  WI S+GGW +F
Sbjct: 134 LADWIHSSGGWAEF 147
>sp|P53563|BCLX_RAT Apoptosis regulator Bcl-X (Bcl-2-like 1 protein)
          Length = 233

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 18/75 (24%), Positives = 37/75 (49%)
 Frame = +2

Query: 155 AFKEFSEIAKKVIEGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLG 334
           A++ F ++  ++   G++W  +   F FG  +  + + K +Q  +S++  W+        
Sbjct: 119 AYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLND-H 177

Query: 335 IFKWIISNGGWRDFL 379
           +  WI  NGGW  F+
Sbjct: 178 LEPWIQENGGWDTFV 192
>sp|Q64373|BCLX_MOUSE Apoptosis regulator Bcl-X (Bcl-2-like 1 protein)
          Length = 233

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 18/75 (24%), Positives = 37/75 (49%)
 Frame = +2

Query: 155 AFKEFSEIAKKVIEGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLG 334
           A++ F ++  ++   G++W  +   F FG  +  + + K +Q  +S++  W+        
Sbjct: 119 AYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLND-H 177

Query: 335 IFKWIISNGGWRDFL 379
           +  WI  NGGW  F+
Sbjct: 178 LEPWIQENGGWDTFV 192
>sp|Q07817|BCLX_HUMAN Apoptosis regulator Bcl-X (Bcl-2-like 1 protein)
          Length = 233

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 18/75 (24%), Positives = 37/75 (49%)
 Frame = +2

Query: 155 AFKEFSEIAKKVIEGGISWKNVATLFYFGYRIARDRLTKGVQHFLSQLLQWIIDIFKGLG 334
           A++ F ++  ++   G++W  +   F FG  +  + + K +Q  +S++  W+        
Sbjct: 119 AYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLND-H 177

Query: 335 IFKWIISNGGWRDFL 379
           +  WI  NGGW  F+
Sbjct: 178 LEPWIQENGGWDTFV 192
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,624,308
Number of Sequences: 369166
Number of extensions: 1171357
Number of successful extensions: 3297
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3230
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3284
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3980545740
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)