Planaria EST Database


DrC_02844

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02844
         (864 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O60518|RNBP6_HUMAN  Ran-binding protein 6 (RanBP6)             199   6e-51
sp|O00410|IMB3_HUMAN  Importin beta-3 (Karyopherin beta-3) (...   199   1e-50
sp|Q8BIV3|RNBP6_MOUSE  Ran-binding protein 6 (RanBP6)             196   7e-50
sp|Q8BKC5|IMB3_MOUSE  Importin beta-3 (Karyopherin beta-3) (...   192   8e-49
sp|O74476|IMB3_SCHPO  Importin beta-3 subunit                     123   6e-28
sp|P32337|IMB3_YEAST  Importin beta-3 subunit (Karyopherin b...    67   8e-11
sp|Q8VI75|IPO4_MOUSE  Importin-4 (Importin 4a) (Imp4a) (Ran-...    54   4e-07
sp|Q8TEX9|IPO4_HUMAN  Importin-4 (Importin 4b) (Imp4b) (Ran-...    50   8e-06
sp|P40069|IMB4_YEAST  Importin beta-4 subunit (Karyopherin b...    45   3e-04
sp|P05527|HMIN_DROME  Homeobox protein invected                    32   3.0  
>sp|O60518|RNBP6_HUMAN Ran-binding protein 6 (RanBP6)
          Length = 1105

 Score =  199 bits (507), Expect = 6e-51
 Identities = 103/255 (40%), Positives = 164/255 (64%), Gaps = 4/255 (1%)
 Frame = +3

Query: 9    DLMHALFLVYKQDALPVFDQLLPNIMKLQEANRPWTDFQYCICFWDDMIESVGGNLSWQY 188
            D++H+LF  YK+  LP F+QLLP I+ L  ++RPW D Q+ +C +DD+IE      S++Y
Sbjct: 852  DILHSLFSTYKEKILPWFEQLLPLIVNLICSSRPWPDRQWGLCIFDDIIEHCSPT-SFKY 910

Query: 189  CQHYLPALIAGLRHDRKEIRQAAIYGFGLMAMHGGIEFTDVLREVAPILVELVETSCSRE 368
             +++   ++  +R +  E+RQAA YG G+MA  GG ++  +  E  P+LV++++ + S+ 
Sbjct: 911  VEYFRWPMLLNMRDNNPEVRQAAAYGLGVMAQFGGDDYRSLCSEAVPLLVKVIKCANSKT 970

Query: 369  EELNMSTENAISALTKICKFRPDCVPGGSLDAFLPTWLSWLPIWEDSEETPHVFGFLCDL 548
            ++  ++TEN ISA+ KI KF+P+CV   ++D  LP WLSWLP+ ED EE      FLCDL
Sbjct: 971  KKNVIATENCISAIGKILKFKPNCV---NVDEVLPHWLSWLPLHEDKEEAIQTLSFLCDL 1027

Query: 549  IENSNSVL----TSNLPHVIRSIAYCIMRDGLSEENPTFRRCLNLVKMVQANGDCFATCV 716
            IE+++ V+     SNLP +I  IA   + + ++ E+P  +R  N+V+ VQ + D +  CV
Sbjct: 1028 IESNHPVVIGPNNSNLPKIISIIAEGKINETINYEDPCAKRLANVVRQVQTSEDLWLECV 1087

Query: 717  NTLSKEEQAALQKAL 761
            + L  E+Q ALQ+ L
Sbjct: 1088 SQLDDEQQEALQELL 1102
>sp|O00410|IMB3_HUMAN Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)
          Length = 1097

 Score =  199 bits (505), Expect = 1e-50
 Identities = 101/255 (39%), Positives = 161/255 (63%), Gaps = 4/255 (1%)
 Frame = +3

Query: 9    DLMHALFLVYKQDALPVFDQLLPNIMKLQEANRPWTDFQYCICFWDDMIESVGGNLSWQY 188
            D++H++F  YK+  LP F+QLLP I+ L   +RPW D Q+ +C +DD+IE      S++Y
Sbjct: 844  DILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVIEHCSP-ASFKY 902

Query: 189  CQHYLPALIAGLRHDRKEIRQAAIYGFGLMAMHGGIEFTDVLREVAPILVELVETSCSRE 368
             +++L  ++  +  +  E+RQAA YG G+MA +GG  +     E  P+LV +++++ S+ 
Sbjct: 903  AEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKT 962

Query: 369  EELNMSTENAISALTKICKFRPDCVPGGSLDAFLPTWLSWLPIWEDSEETPHVFGFLCDL 548
            +E   +TEN ISA+ KI KF+PDCV   +++  LP WLSWLP+ ED EE    F +LCDL
Sbjct: 963  KENVNATENCISAVGKIMKFKPDCV---NVEEVLPHWLSWLPLHEDKEEAVQTFNYLCDL 1019

Query: 549  IENSNSVL----TSNLPHVIRSIAYCIMRDGLSEENPTFRRCLNLVKMVQANGDCFATCV 716
            IE+++ ++     +NLP +   IA   M + +  E+P  +R  N+V+ VQ +G  +  C+
Sbjct: 1020 IESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECI 1079

Query: 717  NTLSKEEQAALQKAL 761
              LS E+QAA+Q+ L
Sbjct: 1080 AQLSPEQQAAIQELL 1094
>sp|Q8BIV3|RNBP6_MOUSE Ran-binding protein 6 (RanBP6)
          Length = 439

 Score =  196 bits (498), Expect = 7e-50
 Identities = 100/255 (39%), Positives = 162/255 (63%), Gaps = 4/255 (1%)
 Frame = +3

Query: 9   DLMHALFLVYKQDALPVFDQLLPNIMKLQEANRPWTDFQYCICFWDDMIESVGGNLSWQY 188
           D++H+LF  YK+  LP F+QLLP I+ L  ++RPW D Q+ +C +DD+IE      S++Y
Sbjct: 186 DILHSLFSTYKEKILPWFEQLLPLIVNLICSSRPWPDRQWGLCIFDDIIEHCSPT-SFKY 244

Query: 189 CQHYLPALIAGLRHDRKEIRQAAIYGFGLMAMHGGIEFTDVLREVAPILVELVETSCSRE 368
            +++   ++  +R +  E+RQAA YG G+MA  GG ++  +  E  P+LV++++ + S+ 
Sbjct: 245 VEYFRWPMLLNMRDNNPEVRQAAAYGLGVMAQFGGDDYRSLCSEAVPLLVKVIKCANSKT 304

Query: 369 EELNMSTENAISALTKICKFRPDCVPGGSLDAFLPTWLSWLPIWEDSEETPHVFGFLCDL 548
           ++  ++TEN ISA+ KI KF+P+CV   ++D  LP WLSWLP+ ED EE      FLCDL
Sbjct: 305 KKNVIATENCISAIGKILKFKPNCV---NVDEVLPHWLSWLPLHEDKEEAIQTLNFLCDL 361

Query: 549 IENSNSVL----TSNLPHVIRSIAYCIMRDGLSEENPTFRRCLNLVKMVQANGDCFATCV 716
           IE+++ V+     SNLP +I  IA   + + +S E+P  +R  N+V+ +Q + + +  C 
Sbjct: 362 IESNHPVVIGPNNSNLPKIISIIAEGKINETISHEDPCAKRLANVVRQIQTSEELWLECT 421

Query: 717 NTLSKEEQAALQKAL 761
           + L  E+Q AL + L
Sbjct: 422 SQLDDEQQEALHELL 436
>sp|Q8BKC5|IMB3_MOUSE Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)
          Length = 1097

 Score =  192 bits (489), Expect = 8e-49
 Identities = 97/255 (38%), Positives = 157/255 (61%), Gaps = 4/255 (1%)
 Frame = +3

Query: 9    DLMHALFLVYKQDALPVFDQLLPNIMKLQEANRPWTDFQYCICFWDDMIESVGGNLSWQY 188
            D++H++F  YK+  LP F+QLLP I+ L    RPW D Q+ +C +DD++E      S++Y
Sbjct: 844  DILHSIFSSYKEKVLPWFEQLLPLIVNLICPQRPWPDRQWGLCIFDDIVEHCSP-ASFKY 902

Query: 189  CQHYLPALIAGLRHDRKEIRQAAIYGFGLMAMHGGIEFTDVLREVAPILVELVETSCSRE 368
             ++++  ++  +  +  E+RQAA YG G+MA  GG  +     +  P+LV +++   ++ 
Sbjct: 903  AEYFISPMLQYVCDNSPEVRQAAAYGLGVMAQFGGDNYRPFCTDALPLLVRVIQAPEAKT 962

Query: 369  EELNMSTENAISALTKICKFRPDCVPGGSLDAFLPTWLSWLPIWEDSEETPHVFGFLCDL 548
            +E   +TEN ISA+ KI KF+PDCV   +++  LP WLSWLP+ ED EE    F +LCDL
Sbjct: 963  KENVNATENCISAVGKIMKFKPDCV---NVEEVLPHWLSWLPLHEDKEEAVQTFSYLCDL 1019

Query: 549  IENSNSVL----TSNLPHVIRSIAYCIMRDGLSEENPTFRRCLNLVKMVQANGDCFATCV 716
            IE+++ ++     +NLP +   IA   M + +  E+P  +R  N+V+ VQ +G  +  C+
Sbjct: 1020 IESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECI 1079

Query: 717  NTLSKEEQAALQKAL 761
              LS E+QAA+Q+ L
Sbjct: 1080 AQLSPEQQAAIQELL 1094
>sp|O74476|IMB3_SCHPO Importin beta-3 subunit
          Length = 1095

 Score =  123 bits (309), Expect = 6e-28
 Identities = 74/239 (30%), Positives = 121/239 (50%)
 Frame = +3

Query: 33   VYKQDALPVFDQLLPNIMKLQEANRPWTDFQYCICFWDDMIESVGGNLSWQYCQHYLPAL 212
            ++K    P +++LLP +      N      Q+ +C  DD+IE  G + SW Y  H+LP L
Sbjct: 857  IHKTAFCPFWERLLPYMDGFLSGNDTVAK-QWALCMMDDLIEFTGPD-SWNYKDHFLPYL 914

Query: 213  IAGLRHDRKEIRQAAIYGFGLMAMHGGIEFTDVLREVAPILVELVETSCSREEELNMSTE 392
              G++    EIRQAA YG G+ A HGG  + ++     P L +++E   +R+EE   +TE
Sbjct: 915  AEGIQSSEPEIRQAASYGIGVAAQHGGELYAEICSSALPALFKMLELPDARDEEQIYATE 974

Query: 393  NAISALTKICKFRPDCVPGGSLDAFLPTWLSWLPIWEDSEETPHVFGFLCDLIENSNSVL 572
            N   A+ KIC+F    V    LD  +  W++ LP+  D ++ P+ + FL +L+E ++  +
Sbjct: 975  NICVAICKICRFCSQRVQ--DLDKVVTYWINTLPVTHDEDDAPYAYTFLAELMEQNHVAV 1032

Query: 573  TSNLPHVIRSIAYCIMRDGLSEENPTFRRCLNLVKMVQANGDCFATCVNTLSKEEQAAL 749
             S +P +I  +A       L     T     + V + +   D   + + TLS + Q AL
Sbjct: 1033 ASQMPTIITILAETFASGVLRGRTLTRLMEASKVYLARFPADQVNSVIATLSVDNQRAL 1091
>sp|P32337|IMB3_YEAST Importin beta-3 subunit (Karyopherin beta-3 subunit) (Protein
            secretion enhancer 1)
          Length = 1089

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 49/166 (29%), Positives = 78/166 (46%), Gaps = 2/166 (1%)
 Frame = +3

Query: 147  DMIESVGGNLSWQYCQHYLPALIAGLRHDRKEIRQAAIYGFGLMAMHGGIEFTDVLREVA 326
            D+I+  GG  +      ++P +   L      IRQAA Y  G+ A +    + DV     
Sbjct: 885  DLIQ-YGGEQTASMKNAFIPKVTECLISPDARIRQAASYIIGVCAQYAPSTYADVCIPTL 943

Query: 327  PILVELVETSCSREEELNMSTENAISALTKICKFRPDCVPGGSLDAFLPTWLSWLPIWED 506
              LV++V+   S+ EE   STENA +A+ KI       +P  ++D +   W   LP   D
Sbjct: 944  DTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNIP--NVDTYTANWFKTLPTITD 1001

Query: 507  SEETPHVFGFLCDLIENSNSVL--TSNLPHVIRSIAYCIMRDGLSE 638
             E     + FL  LIEN++ ++   SN+  V+ S+   +    L+E
Sbjct: 1002 KEAASFNYQFLSQLIENNSPIVCAQSNISAVVDSVIQALNERSLTE 1047
>sp|Q8VI75|IPO4_MOUSE Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4)
          Length = 1082

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 53/233 (22%), Positives = 95/233 (40%)
 Frame = +3

Query: 54   PVFDQLLPNIMKLQEANRPWTDFQYCICFWDDMIESVGGNLSWQYCQHYLPALIAGLRHD 233
            P F   LP ++   + +    +  + +    + I+ +G   S Q+     P L+   R  
Sbjct: 854  PFFATFLPLLLCKTKQSCTVAEKSFAVGTLAESIQGLG-TASAQFVSRLFPVLLNNAREA 912

Query: 234  RKEIRQAAIYGFGLMAMHGGIEFTDVLREVAPILVELVETSCSREEELNMSTENAISALT 413
              E+R  AI+G G++A HGG    D   ++  +L+ L+       E  +   +N   AL 
Sbjct: 913  DPEVRSNAIFGLGVLAEHGGCPAQDHFPKLLGLLLPLL-----ARERHDRVRDNICGALA 967

Query: 414  KICKFRPDCVPGGSLDAFLPTWLSWLPIWEDSEETPHVFGFLCDLIENSNSVLTSNLPHV 593
            ++    P    G +    L T L  LP+ ED EE   + G L   +  +N     ++   
Sbjct: 968  RVLMASP---VGKTEPQVLATLLRALPLKEDMEEWLTI-GHLFSFLHQNNPEQVVDVASE 1023

Query: 594  IRSIAYCIMRDGLSEENPTFRRCLNLVKMVQANGDCFATCVNTLSKEEQAALQ 752
            +  I   I+ D     +      L L  + + + D F T + +L  ++   LQ
Sbjct: 1024 LLRICSLILPDNRIPPDTKAALLLLLTFLAKQHTDSFHTALGSLPNDKAQELQ 1076
>sp|Q8TEX9|IPO4_HUMAN Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4)
          Length = 1081

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 51/198 (25%), Positives = 84/198 (42%)
 Frame = +3

Query: 168  GNLSWQYCQHYLPALIAGLRHDRKEIRQAAIYGFGLMAMHGGIEFTDVLREVAPILVELV 347
            G  S Q+    LP L++  +    E+R  AI+G G++A HGG       +E  P L+ L+
Sbjct: 890  GAASAQFVSRLLPVLLSTAQEADPEVRSNAIFGMGVLAEHGG----HPAQEHFPKLLGLL 945

Query: 348  ETSCSREEELNMSTENAISALTKICKFRPDCVPGGSLDAFLPTWLSWLPIWEDSEETPHV 527
                +RE   +   +N   AL ++    P   P   + A L   L  LP+ ED EE   +
Sbjct: 946  FPLLARERH-DRVRDNICGALARLLMASPTRKPEPQVLAAL---LHALPLKEDLEEWVTI 1001

Query: 528  FGFLCDLIENSNSVLTSNLPHVIRSIAYCIMRDGLSEENPTFRRCLNLVKMVQANGDCFA 707
                  L ++S   +    P ++R I   I+ D     +      L L  + + + D F 
Sbjct: 1002 GRLFSFLYQSSPDQVIDVAPELLR-ICSLILADNKIPPDTKAALLLLLTFLAKQHTDSFQ 1060

Query: 708  TCVNTLSKEEQAALQKAL 761
              + +L  ++   LQ  L
Sbjct: 1061 AALGSLPVDKAQELQAVL 1078
>sp|P40069|IMB4_YEAST Importin beta-4 subunit (Karyopherin beta-4 subunit) (Ran-binding
            protein YRB4)
          Length = 1113

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 53/226 (23%), Positives = 94/226 (41%), Gaps = 13/226 (5%)
 Frame = +3

Query: 186  YCQHYLPALIAGLRHDRK-EIRQAAIYGFGLMAMHGGIEFTDVLREVAPILVELV----- 347
            +    L AL+  L  D+  E+R  A YG GL+  +  ++ + V   V   L EL+     
Sbjct: 900  FVHEMLEALVIRLTSDKSLEVRGNAAYGVGLLCEYASMDISAVYEPVLKALYELLSAADQ 959

Query: 348  -----ETSCSREEELNMSTENAISALTKICKFRPDCVPGGSLDAFLPTWLSWLPIWEDSE 512
                 E   +  E ++ +  NA   + ++       VP   L+  +P  L+ LP+    E
Sbjct: 960  KALAAEDDEATREIIDRAYANASGCVARMALKNSALVP---LEQTVPALLAHLPLNTGFE 1016

Query: 513  ETPHVFGFLCDLIENSNSVLTSNLPHVIRSIAYCIMRDGLSEENPTFRRCLNLVKMVQAN 692
            E   +F  +  L + ++ V+T+  P +I      I     ++EN       + +K+ +  
Sbjct: 1017 EYNPIFELIMKLYQENSPVITNETPRIIE-----IFSAVFTKEN-------DRIKLEKE- 1063

Query: 693  GDCFATCVNTLSKEE--QAALQKALERSQNNCAE*RKYLCSTYEFI 824
                    +TL +EE  +   Q   E  ++   E  KYL +TY  I
Sbjct: 1064 --------STLGREENMERLKQFQTEEMKHKVIELLKYLNTTYNGI 1101
>sp|P05527|HMIN_DROME Homeobox protein invected
          Length = 576

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
 Frame = -3

Query: 520 GVSSLSSHIGSQLNHVGRNASRLP--PGTQSGRNLQILVSALMAFSVLIFSSSSREHDVS 347
           G S   S  GS  N    N +R P     +SG+ L +  S   A S L FSSS      +
Sbjct: 305 GGSVSGSSTGSSKNSGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSSLSFSSSLANICSN 364

Query: 346 TNSTRIGATSRKTSVNSIPPCIAIRPNP 263
           +N +   ATS  T+  S  P   ++  P
Sbjct: 365 SNDSNSTATSSSTTNTSGAPVDLVKSPP 392
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,220,379
Number of Sequences: 369166
Number of extensions: 2145916
Number of successful extensions: 5848
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5627
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5835
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8582957970
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)