Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02843 (619 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q01405|SC23A_MOUSE Protein transport protein Sec23A (SEC... 231 1e-60 sp|Q9D662|SC23B_MOUSE Protein transport protein Sec23B (SEC... 230 2e-60 sp|Q15436|SC23A_HUMAN Protein transport protein Sec23A (SEC... 230 2e-60 sp|Q15437|SC23B_HUMAN Protein transport protein Sec23B (SEC... 223 3e-58 sp|P15303|SEC23_YEAST Protein transport protein SEC23 165 8e-41 sp|P38769|YHJ5_YEAST Hypothetical 72.3 kDa protein in SLT2-... 61 3e-09 sp|Q75E74|ATG2_ASHGO Autophagy-related protein 2 32 1.7 sp|O94855|SC24D_HUMAN Protein transport protein Sec24D (SEC... 31 2.9 sp|Q7NBM9|SYN_MYCGA Asparaginyl-tRNA synthetase (Asparagine... 30 5.0 sp|Q9CQX5|CC004_MOUSE Protein C3orf4 homolog 30 6.5
>sp|Q01405|SC23A_MOUSE Protein transport protein Sec23A (SEC23-related protein A) Length = 765 Score = 231 bits (589), Expect = 1e-60 Identities = 111/182 (60%), Positives = 140/182 (76%), Gaps = 2/182 (1%) Frame = +1 Query: 79 PSNKFLQPLGECDMVLTDLIEELQPDSWPVGQGKRPLRCVGAALNMAISLLEATYPNTVA 258 PSN+FLQP+ + DM LTDL+ ELQ D WPV QGKRPLR G AL++A+ LLE T+PNT A Sbjct: 225 PSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGA 284 Query: 259 RIMTFIGGPCTIGPGLIIDDDLKNIIRSHHDIEKDDCPYMKKAIKHYESLANRAAQNGFV 438 RIM FIGGP T GPG+++ D+LK IRS HDIEKD+ Y+KK KH+E+LANRAA G V Sbjct: 285 RIMMFIGGPATQGPGMVVGDELKTPIRSWHDIEKDNAKYVKKGTKHFEALANRAATTGHV 344 Query: 439 VDIFSCSLDQTGLHEMRFLPNYTGGHMIMADSFESQLFQQSFKRVFAMD--NTFRMDFGA 612 +DI++C+LDQTGL EM+ PN TGG+M+M DSF + LF+Q+F+RVF D F+M FG Sbjct: 345 IDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDIHGQFKMGFGG 404 Query: 613 TI 618 T+ Sbjct: 405 TL 406
>sp|Q9D662|SC23B_MOUSE Protein transport protein Sec23B (SEC23-related protein B) Length = 767 Score = 230 bits (586), Expect = 2e-60 Identities = 111/181 (61%), Positives = 139/181 (76%), Gaps = 2/181 (1%) Frame = +1 Query: 82 SNKFLQPLGECDMVLTDLIEELQPDSWPVGQGKRPLRCVGAALNMAISLLEATYPNTVAR 261 S++FLQP+ + DM LTDL+ ELQ D WPV QGKRPLR G AL++A+ LLE T+PNT AR Sbjct: 228 SSRFLQPIHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGAR 287 Query: 262 IMTFIGGPCTIGPGLIIDDDLKNIIRSHHDIEKDDCPYMKKAIKHYESLANRAAQNGFVV 441 IM F GGP T GPG+++ D+LK IRS HDIEKD+ +MKKA KHYE LANR A NG + Sbjct: 288 IMLFTGGPPTQGPGMVVGDELKTPIRSWHDIEKDNARFMKKATKHYEMLANRTATNGHCI 347 Query: 442 DIFSCSLDQTGLHEMRFLPNYTGGHMIMADSFESQLFQQSFKRVFAMD--NTFRMDFGAT 615 DI++C+LDQTGL EM+ PN TGGHM+M DSF + LF+Q+F+R+F+ D FRM FGAT Sbjct: 348 DIYACALDQTGLLEMKCCPNLTGGHMVMGDSFNTSLFKQTFQRIFSKDFNGDFRMAFGAT 407 Query: 616 I 618 + Sbjct: 408 L 408
>sp|Q15436|SC23A_HUMAN Protein transport protein Sec23A (SEC23-related protein A) Length = 765 Score = 230 bits (586), Expect = 2e-60 Identities = 110/182 (60%), Positives = 140/182 (76%), Gaps = 2/182 (1%) Frame = +1 Query: 79 PSNKFLQPLGECDMVLTDLIEELQPDSWPVGQGKRPLRCVGAALNMAISLLEATYPNTVA 258 PSN+FLQP+ + DM LTDL+ ELQ D WPV QGKRPLR G AL++A+ LLE T+PNT A Sbjct: 225 PSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGA 284 Query: 259 RIMTFIGGPCTIGPGLIIDDDLKNIIRSHHDIEKDDCPYMKKAIKHYESLANRAAQNGFV 438 RIM FIGGP T GPG+++ D+LK IRS HDI+KD+ Y+KK KH+E+LANRAA G V Sbjct: 285 RIMMFIGGPATQGPGMVVGDELKTPIRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHV 344 Query: 439 VDIFSCSLDQTGLHEMRFLPNYTGGHMIMADSFESQLFQQSFKRVFAMD--NTFRMDFGA 612 +DI++C+LDQTGL EM+ PN TGG+M+M DSF + LF+Q+F+RVF D F+M FG Sbjct: 345 IDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGG 404 Query: 613 TI 618 T+ Sbjct: 405 TL 406
>sp|Q15437|SC23B_HUMAN Protein transport protein Sec23B (SEC23-related protein B) Length = 767 Score = 223 bits (568), Expect = 3e-58 Identities = 111/188 (59%), Positives = 139/188 (73%), Gaps = 3/188 (1%) Frame = +1 Query: 64 PASH-LPSNKFLQPLGECDMVLTDLIEELQPDSWPVGQGKRPLRCVGAALNMAISLLEAT 240 P H S++FLQP+ + DM LTDL+ ELQ D WPV QGKRPLR G AL++A+ LLE T Sbjct: 221 PQEHPFASSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGT 280 Query: 241 YPNTVARIMTFIGGPCTIGPGLIIDDDLKNIIRSHHDIEKDDCPYMKKAIKHYESLANRA 420 +PNT ARIM F GGP T GPG+++ D+LK IRS HDIEKD+ +MKKA KHYE LANR Sbjct: 281 FPNTGARIMLFTGGPPTQGPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRT 340 Query: 421 AQNGFVVDIFSCSLDQTGLHEMRFLPNYTGGHMIMADSFESQLFQQSFKRVFAMD--NTF 594 A NG +DI++C+LDQTGL EM+ N TGG+M+M DSF + LF+Q+F+R+F D F Sbjct: 341 AANGHCIDIYACALDQTGLLEMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDF 400 Query: 595 RMDFGATI 618 RM FGAT+ Sbjct: 401 RMAFGATL 408
>sp|P15303|SEC23_YEAST Protein transport protein SEC23 Length = 768 Score = 165 bits (418), Expect = 8e-41 Identities = 83/183 (45%), Positives = 114/183 (62%), Gaps = 10/183 (5%) Frame = +1 Query: 67 ASHLPS----------NKFLQPLGECDMVLTDLIEELQPDSWPVGQGKRPLRCVGAALNM 216 ASHLP+ N+F PL + + L L+E L PD W V G RPLR G+ALN+ Sbjct: 209 ASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNI 268 Query: 217 AISLLEATYPNTVARIMTFIGGPCTIGPGLIIDDDLKNIIRSHHDIEKDDCPYMKKAIKH 396 A LL+ Y N ARI+ F GP T+ PGLI++ +LK+ +RSHHDI+ D + KKA K Sbjct: 269 ASLLLQGCYKNIPARIILFASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKF 328 Query: 397 YESLANRAAQNGFVVDIFSCSLDQTGLHEMRFLPNYTGGHMIMADSFESQLFQQSFKRVF 576 Y +A R A NG VDIF+ DQ G+ EM+ L + TGG +++ D+F + +F+QS+ R+F Sbjct: 329 YNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLF 388 Query: 577 AMD 585 A D Sbjct: 389 AKD 391
>sp|P38769|YHJ5_YEAST Hypothetical 72.3 kDa protein in SLT2-PUT2 intergenic region Length = 630 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/134 (29%), Positives = 60/134 (44%), Gaps = 3/134 (2%) Frame = +1 Query: 178 KRPLRCVGAALNMAISLLEATYPNTVARIMTFIGGPCTIGPGLIIDDDLKNIIRSHHDIE 357 KR RC G AL ++ L + I++F+ GPCT G G ++ + +R +H E Sbjct: 199 KRDKRCTGLALFVSSVLASQCSLSAYCHIVSFLNGPCTKGGGKVMSRERGESMRQNHHFE 258 Query: 358 --KDDCPYMKKAIKHYESLANRAAQNGFVVDIFSCSLDQTGLHEMRFLPNYTGGHMI-MA 528 K K Y+ + + A + + F SLDQ G+ EM P T + Sbjct: 259 SKSSQLQLSKSPTKFYKKMLEKFANQSLIYEFFIASLDQIGILEMS--PLITSSMAVSQF 316 Query: 529 DSFESQLFQQSFKR 570 DSF + F SF++ Sbjct: 317 DSFNDERFAMSFQK 330
>sp|Q75E74|ATG2_ASHGO Autophagy-related protein 2 Length = 1525 Score = 31.6 bits (70), Expect = 1.7 Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 5/57 (8%) Frame = +1 Query: 319 DLKNIIRSHHDIEKDDCPYMKKAI-KHYESLANRAAQNGFVV----DIFSCSLDQTG 474 + K IIRS + DDC MK +I + +ESL ++ GF V + SC++ Q+G Sbjct: 783 NFKCIIRSPTFMLADDCSNMKTSITESWESLVRYYSKAGFAVIGKSGLLSCTIKQSG 839
>sp|O94855|SC24D_HUMAN Protein transport protein Sec24D (SEC24-related protein D) Length = 1032 Score = 30.8 bits (68), Expect = 2.9 Identities = 24/110 (21%), Positives = 46/110 (41%) Frame = +1 Query: 283 PCTIGPGLIIDDDLKNIIRSHHDIEKDDCPYMKKAIKHYESLANRAAQNGFVVDIFSCSL 462 P PG + + D K ++ + +K+ + + Y+SLA +G V +F Sbjct: 585 PTAEAPGKLKNRDDKKLVNT----DKEKILFQPQT-NVYDSLAKDCVAHGCSVTLFLFPS 639 Query: 463 DQTGLHEMRFLPNYTGGHMIMADSFESQLFQQSFKRVFAMDNTFRMDFGA 612 + + +P TGG + ++F+ L +Q F D ++ F A Sbjct: 640 QYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQFLNDLRNDIEKKIGFDA 689
>sp|Q7NBM9|SYN_MYCGA Asparaginyl-tRNA synthetase (Asparagine--tRNA ligase) (AsnRS) Length = 457 Score = 30.0 bits (66), Expect = 5.0 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Frame = +1 Query: 496 PNYTG--GHMIMADSFESQLFQQSFKRVFAMDNTFRMD 603 PNY G + ++ F ++ + Q FKRVF TFR + Sbjct: 184 PNYFGKKASLTVSGQFAAEAYAQGFKRVFTFGPTFRAE 221
>sp|Q9CQX5|CC004_MOUSE Protein C3orf4 homolog Length = 253 Score = 29.6 bits (65), Expect = 6.5 Identities = 11/37 (29%), Positives = 18/37 (48%) Frame = +1 Query: 187 LRCVGAALNMAISLLEATYPNTVARIMTFIGGPCTIG 297 L C GA + + + + YP I+ + G CT+G Sbjct: 150 LMCFGALIGLCACICRSLYPTLATGILHLLAGLCTLG 186
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 74,641,121 Number of Sequences: 369166 Number of extensions: 1521116 Number of successful extensions: 3510 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3426 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3510 length of database: 68,354,980 effective HSP length: 105 effective length of database: 48,957,805 effective search space used: 4895780500 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)