Planaria EST Database


DrC_02824

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02824
         (553 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8NCC3|LYPA3_HUMAN  1-O-acylceramide synthase precursor (...    82   7e-16
sp|Q8VEB4|LYPA3_MOUSE  1-O-acylceramide synthase precursor (...    80   3e-15
sp|P18424|LCAT_RAT  Phosphatidylcholine-sterol acyltransfera...    79   6e-15
sp|P16301|LCAT_MOUSE  Phosphatidylcholine-sterol acyltransfe...    78   1e-14
sp|P53760|LCAT_CHICK  Phosphatidylcholine-sterol acyltransfe...    69   1e-11
sp|P04180|LCAT_HUMAN  Phosphatidylcholine-sterol acyltransfe...    68   2e-11
sp|O35724|LCAT_MICMN  Phosphatidylcholine-sterol acyltransfe...    68   2e-11
sp|Q08758|LCAT_PAPAN  Phosphatidylcholine-sterol acyltransfe...    67   2e-11
sp|O35840|LCAT_TATKG  Phosphatidylcholine-sterol acyltransfe...    66   6e-11
sp|P53761|LCAT_RABIT  Phosphatidylcholine-sterol acyltransfe...    62   7e-10
>sp|Q8NCC3|LYPA3_HUMAN 1-O-acylceramide synthase precursor (ACS) (Lysosomal phospholipase
           A2) (Lysophospholipase 3) (LPLA2) (LCAT-like
           lysophospholipase) (LLPL)
          Length = 412

 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 60/189 (31%), Positives = 98/189 (51%), Gaps = 12/189 (6%)
 Frame = +3

Query: 21  HLMAIIKGLLIFQIICIVGNLQICSSKVLNDSKIPSPIILVPGDGGSRAYSMVD-----Y 185
           HL     GLL   ++ ++  L + +   L   + P P++LVPGD G++  + +D     +
Sbjct: 4   HLRPYRVGLLPDGLLFLLLLLMLLADPALPAGRHP-PVVLVPGDLGNQLEAKLDKPTVVH 62

Query: 186 RLFTTKV----LVWVNFEYML---FPSFLRNVFQLEYNPDTHNTSNMKGSDVFFPGWGDT 344
            L + K      +W+N E +L      ++ N+ +L YN  +  T    G DV  PG+G T
Sbjct: 63  YLCSKKTESYFTIWLNLELLLPVIIDCWIDNI-RLVYNKTSRATQFPDGVDVRVPGFGKT 121

Query: 345 DTIEELDEKLHIQTTYFSNLVNNLVTDKFYVRNKTVRGAPYDFRKAPNENQEMIQKMKLL 524
            ++E LD       +YF  +V +LV    Y R + VRGAPYD+R+APNEN      ++ +
Sbjct: 122 FSLEFLDPSKSSVGSYFHTMVESLV-GWGYTRGEDVRGAPYDWRRAPNENGPYFLALREM 180

Query: 525 VEDTYRQSG 551
           +E+ Y+  G
Sbjct: 181 IEEMYQLYG 189
>sp|Q8VEB4|LYPA3_MOUSE 1-O-acylceramide synthase precursor (ACS) (Lysosomal phospholipase
           A2) (Lysophospholipase 3) (LCAT-like lysophospholipase)
           (LLPL)
          Length = 412

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 55/166 (33%), Positives = 90/166 (54%), Gaps = 16/166 (9%)
 Frame = +3

Query: 102 VLNDSKIPS----PIILVPGDGGSRAYSMVD-----YRLFTTKV----LVWVNFEYML-- 236
           +L D  +P+    P++LVPGD G++  + +D     + L + K      +W+N E +L  
Sbjct: 26  MLADLTLPAQRHPPVVLVPGDLGNQLEAKLDKPKVVHYLCSKKTDSYFTLWLNLELLLPV 85

Query: 237 -FPSFLRNVFQLEYNPDTHNTSNMKGSDVFFPGWGDTDTIEELDEKLHIQTTYFSNLVNN 413
               ++ N+ +L YN  +  T    G DV  PG+G+T ++E LD       +YF  +V +
Sbjct: 86  IIDCWIDNI-RLVYNRTSRATQFPDGVDVRVPGFGETFSMEFLDPSKRNVGSYFYTMVES 144

Query: 414 LVTDKFYVRNKTVRGAPYDFRKAPNENQEMIQKMKLLVEDTYRQSG 551
           LV    Y R + VRGAPYD+R+APNEN      ++ ++E+ Y+  G
Sbjct: 145 LV-GWGYTRGEDVRGAPYDWRRAPNENGPYFLALREMIEEMYQMYG 189
>sp|P18424|LCAT_RAT Phosphatidylcholine-sterol acyltransferase precursor
           (Lecithin-cholesterol acyltransferase)
           (Phospholipid-cholesterol acyltransferase)
          Length = 440

 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 54/153 (35%), Positives = 80/153 (52%), Gaps = 12/153 (7%)
 Frame = +3

Query: 129 PIILVPGDGGSRAYSMVD---------YRLFTTKVLVWVNFEYML---FPSFLRNVFQLE 272
           P+ILVPG  G+R  + +D         YR       +W++F   L      ++ N  ++ 
Sbjct: 48  PVILVPGCMGNRLEAKLDKPNVVNWLCYRKTEDFFTIWLDFNMFLPLGVDCWIDNT-RVV 106

Query: 273 YNPDTHNTSNMKGSDVFFPGWGDTDTIEELDEKLHIQTTYFSNLVNNLVTDKFYVRNKTV 452
           YN  + + SN  G  +  PG+G T ++E LD+       Y + LV NLV +  YVR++TV
Sbjct: 107 YNRSSGHMSNAPGVQIRVPGFGKTYSVEYLDDNK--LAGYLNTLVQNLVNNG-YVRDETV 163

Query: 453 RGAPYDFRKAPNENQEMIQKMKLLVEDTYRQSG 551
           R APYD+R AP +  E  QK+  LVE+ Y   G
Sbjct: 164 RAAPYDWRLAPRQQDEYYQKLAGLVEEMYAAYG 196
>sp|P16301|LCAT_MOUSE Phosphatidylcholine-sterol acyltransferase precursor
           (Lecithin-cholesterol acyltransferase)
           (Phospholipid-cholesterol acyltransferase)
          Length = 438

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 52/153 (33%), Positives = 80/153 (52%), Gaps = 12/153 (7%)
 Frame = +3

Query: 129 PIILVPGDGGSRAYSMVD---------YRLFTTKVLVWVNFEYML---FPSFLRNVFQLE 272
           P+ILVPG  G+R  + +D         YR       +W++F   L      ++ N  ++ 
Sbjct: 48  PVILVPGCLGNRLEAKLDKPDVVNWMCYRKTEDFFTIWLDFNLFLPLGVDCWIDNT-RIV 106

Query: 273 YNPDTHNTSNMKGSDVFFPGWGDTDTIEELDEKLHIQTTYFSNLVNNLVTDKFYVRNKTV 452
           YN  +   SN  G  +  PG+G T+++E +D+       Y   LV NLV +  YVR++TV
Sbjct: 107 YNHSSGRVSNAPGVQIRVPGFGKTESVEYVDDNK--LAGYLHTLVQNLVNNG-YVRDETV 163

Query: 453 RGAPYDFRKAPNENQEMIQKMKLLVEDTYRQSG 551
           R APYD+R AP++  E  +K+  LVE+ Y   G
Sbjct: 164 RAAPYDWRLAPHQQDEYYKKLAGLVEEMYAAYG 196
>sp|P53760|LCAT_CHICK Phosphatidylcholine-sterol acyltransferase precursor
           (Lecithin-cholesterol acyltransferase)
           (Phospholipid-cholesterol acyltransferase)
          Length = 413

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 15/154 (9%)
 Frame = +3

Query: 129 PIILVPGDGGSRAYSMVD---------YRLFTTKVLVWVNFEYML---FPSFLRNVFQLE 272
           P  LVPG  G++  + +D         YR       +W+N    L      ++ N  ++ 
Sbjct: 46  PWCLVPGFLGNQLEAKLDKPDVVNWMCYRKTEDYFTIWLNLNTFLPVGVDCWIDNT-RVV 104

Query: 273 YNPDTHNTSNMKGSDVFFPGWGDTDTIEELDEKLHIQTTYFSNLVNNLVTDKFYVRNKTV 452
           YN      +N  G  +  PG+G T ++E LD+       Y   LV NLV +  YVR++TV
Sbjct: 105 YNRTARKMTNAPGVHIRVPGFGKTYSVEYLDQSK--LAGYLHTLVQNLVNNG-YVRDQTV 161

Query: 453 RGAPYDFRKAPNENQEMIQKMKLLVE---DTYRQ 545
           R APYD+R  P E  E  Q +K L+E   D Y+Q
Sbjct: 162 RAAPYDWRVGPQEQPEYFQNLKALIEEMHDEYQQ 195
>sp|P04180|LCAT_HUMAN Phosphatidylcholine-sterol acyltransferase precursor
           (Lecithin-cholesterol acyltransferase)
           (Phospholipid-cholesterol acyltransferase)
          Length = 440

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 49/153 (32%), Positives = 76/153 (49%), Gaps = 12/153 (7%)
 Frame = +3

Query: 129 PIILVPGDGGSRAYSMVD---------YRLFTTKVLVWVNFEYML---FPSFLRNVFQLE 272
           P+ILVPG  G++  + +D         YR       +W++    L      ++ N  ++ 
Sbjct: 48  PVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNT-RVV 106

Query: 273 YNPDTHNTSNMKGSDVFFPGWGDTDTIEELDEKLHIQTTYFSNLVNNLVTDKFYVRNKTV 452
           YN  +   SN  G  +  PG+G T ++E LD        Y   LV NLV +  YVR++TV
Sbjct: 107 YNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSK--LAGYLHTLVQNLVNNG-YVRDETV 163

Query: 453 RGAPYDFRKAPNENQEMIQKMKLLVEDTYRQSG 551
           R APYD+R  P + +E  +K+  LVE+ +   G
Sbjct: 164 RAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYG 196
>sp|O35724|LCAT_MICMN Phosphatidylcholine-sterol acyltransferase (Lecithin-cholesterol
           acyltransferase) (Phospholipid-cholesterol
           acyltransferase)
          Length = 299

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 39/93 (41%), Positives = 53/93 (56%)
 Frame = +3

Query: 273 YNPDTHNTSNMKGSDVFFPGWGDTDTIEELDEKLHIQTTYFSNLVNNLVTDKFYVRNKTV 452
           YN  +   SN  G  +  PG+G T ++E LD+       Y   LV NLV +  YVR++TV
Sbjct: 27  YNRSSGRMSNAPGVQIRVPGFGKTYSVEYLDDNK--LAGYLHTLVQNLVNNA-YVRDETV 83

Query: 453 RGAPYDFRKAPNENQEMIQKMKLLVEDTYRQSG 551
           R APYD+R AP++  E  QK+  LVE+ Y   G
Sbjct: 84  RAAPYDWRLAPSQQDEYYQKLAELVEEMYDAYG 116
>sp|Q08758|LCAT_PAPAN Phosphatidylcholine-sterol acyltransferase precursor
           (Lecithin-cholesterol acyltransferase)
           (Phospholipid-cholesterol acyltransferase)
          Length = 440

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 49/153 (32%), Positives = 75/153 (49%), Gaps = 12/153 (7%)
 Frame = +3

Query: 129 PIILVPGDGGSRAYSMVD---------YRLFTTKVLVWVNFEYML---FPSFLRNVFQLE 272
           P+ILVPG  G++  + +D         YR       +W++    L      ++ N  ++ 
Sbjct: 48  PVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNT-RVV 106

Query: 273 YNPDTHNTSNMKGSDVFFPGWGDTDTIEELDEKLHIQTTYFSNLVNNLVTDKFYVRNKTV 452
           YN  +   SN  G  +  PG+G T ++E LD        Y   LV NLV +  YVR++TV
Sbjct: 107 YNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSK--LAGYLHTLVQNLVNNG-YVRDETV 163

Query: 453 RGAPYDFRKAPNENQEMIQKMKLLVEDTYRQSG 551
           R APYD+R  P + +E   K+  LVE+ +   G
Sbjct: 164 RAAPYDWRLEPGQQEEYYHKLAGLVEEMHAAYG 196
>sp|O35840|LCAT_TATKG Phosphatidylcholine-sterol acyltransferase (Lecithin-cholesterol
           acyltransferase) (Phospholipid-cholesterol
           acyltransferase)
          Length = 293

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 36/93 (38%), Positives = 54/93 (58%)
 Frame = +3

Query: 273 YNPDTHNTSNMKGSDVFFPGWGDTDTIEELDEKLHIQTTYFSNLVNNLVTDKFYVRNKTV 452
           YN  +   SN  G ++  PG+G T ++E LD+    +  Y   LV NLV +  YVR++TV
Sbjct: 25  YNRSSGRVSNAPGVEIRVPGFGKTYSVEYLDDNKLAE--YMHTLVQNLVNNG-YVRDETV 81

Query: 453 RGAPYDFRKAPNENQEMIQKMKLLVEDTYRQSG 551
           R APYD+R  P++  +  QK+  L+E+ Y   G
Sbjct: 82  RAAPYDWRLEPSQQDDYYQKLAGLIEEMYAAYG 114
>sp|P53761|LCAT_RABIT Phosphatidylcholine-sterol acyltransferase precursor
           (Lecithin-cholesterol acyltransferase)
           (Phospholipid-cholesterol acyltransferase)
          Length = 440

 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 47/153 (30%), Positives = 74/153 (48%), Gaps = 12/153 (7%)
 Frame = +3

Query: 129 PIILVPGDGGSRAYSMVD---------YRLFTTKVLVWVNFEYML---FPSFLRNVFQLE 272
           P+ILVPG  G++  + +D         YR       +W++    L      ++ N  ++ 
Sbjct: 48  PVILVPGCLGNQLEAKLDKPSVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNT-RVV 106

Query: 273 YNPDTHNTSNMKGSDVFFPGWGDTDTIEELDEKLHIQTTYFSNLVNNLVTDKFYVRNKTV 452
           YN  +       G  +  PG+G T ++E LD        Y   LV NLV +  YVR++TV
Sbjct: 107 YNRSSGRVVISPGVQIRVPGFGKTYSVEYLDNNK--LAGYMHTLVQNLVNNG-YVRDETV 163

Query: 453 RGAPYDFRKAPNENQEMIQKMKLLVEDTYRQSG 551
           R APYD+R  P++ +E   K+  LVE+ +   G
Sbjct: 164 RAAPYDWRLEPSQQEEYYGKLAGLVEEMHAAYG 196
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,165,207
Number of Sequences: 369166
Number of extensions: 1407488
Number of successful extensions: 3477
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3395
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3464
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3882260660
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)