Planaria EST Database


DrC_02790

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02790
         (888 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O42184|REST_CHICK  Restin (Cytoplasmic linker protein 170...    57   5e-08
sp|Q58718|RAD50_METJA  DNA double-strand break repair rad50 ...    56   1e-07
sp|Q13439|GOGA4_HUMAN  Golgin subfamily A member 4 (Trans-Go...    55   3e-07
sp|Q59037|SMC_METJA  Chromosome partition protein smc homolog      50   6e-06
sp|P30622|REST_HUMAN  Restin (Cytoplasmic linker protein 170...    49   1e-05
sp|Q9FLH0|NMCP_ARATH  Putative nuclear matrix constituent pr...    49   1e-05
sp|Q60803|TRAF3_MOUSE  TNF receptor-associated factor 3 (CD4...    49   2e-05
sp|Q13114|TRAF3_HUMAN  TNF receptor-associated factor 3 (CD4...    48   4e-05
sp|Q96YR5|RAD50_SULTO  DNA double-strand break repair rad50 ...    48   4e-05
sp|Q66GS9|CEP4_HUMAN  Centrosomal protein 4 (Centrosomal pro...    47   5e-05
>sp|O42184|REST_CHICK Restin (Cytoplasmic linker protein 170) (CLIP-170)
          Length = 1433

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 62/265 (23%), Positives = 119/265 (44%), Gaps = 10/265 (3%)
 Frame = +2

Query: 59   LESRANNQISNLIMKCPEEMCSFECELLEMSEHLRICGKKSVECPFY---------KLGC 211
            L+++   + S +I K   ++  F+  LL+  E L+   KK+ E             +   
Sbjct: 1009 LQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKA 1068

Query: 212  DVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKELKN 391
            D R     + +E    E +  ++  I+ + +++N     R+   K   E++ L++  LKN
Sbjct: 1069 DKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENS----RQTNEKLQNELDMLKQNNLKN 1124

Query: 392  HEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQEKE 571
             EE+ K +E L L+++K+E +                +L +++E  NV++A+       E
Sbjct: 1125 EEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQE-ENVKLAEELGRSRDE 1183

Query: 572  MQSIKTEKEELDDQMRIKLRNIWYKIDEIELELKKRCESDKIESIKLDLIEKIDVFQGNF 751
            + S +  +EE     R  L N   ++ + E  LKK     +I+  +  L + I       
Sbjct: 1184 VTSHQKLEEE-----RSVLNNQLLEMKKRESTLKK-----EIDEERASLQKSISDTSALI 1233

Query: 752  DKKIDEIEWL-NQIGIFRTENKSIR 823
             +K +E+E L N+I + R EN S +
Sbjct: 1234 TQKDEELEKLRNEITVLRGENASAK 1258
>sp|Q58718|RAD50_METJA DNA double-strand break repair rad50 ATPase
          Length = 1005

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 62/247 (25%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
 Frame = +2

Query: 173  KKSVECPFYKLGCDVRKMTNE-KLIEHFQLENN-NHNKTLIDMIDNIKNEVGELREKELK 346
            KKS+E     L   + K+  E K I+   +EN+    +    +++N++ E  EL +K  +
Sbjct: 421  KKSIEKNINDLETRINKLLEETKNIDIESIENSLKEIEEKKKVLENLQKEKIELNKKLGE 480

Query: 347  NHEEINKLRE--KELKNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVE 520
             + EI +L++   ELK  E    L +    +++K+E IN                 K + 
Sbjct: 481  INSEIKRLKKILDELKEVEGKCPLCKTPIDENKKMELINQHKTQLNNKYTELEEINKKIR 540

Query: 521  EIFNVEIAKLKSEQEKE--MQSIKT---EKEELDDQMRIKLRNIWYKIDEIELELKKRCE 685
            EI   +I KLK E +KE  ++++KT   EK+   +++ +KL+N   ++DEI  ++     
Sbjct: 541  EI-EKDIEKLKKEIDKEENLKTLKTLYLEKQSQIEELELKLKNYKEQLDEINKKISNYVI 599

Query: 686  SDK-IESIKLDLIEKIDVFQGNFDKKIDEIEWLNQI---GIFRTENKSI--------RRK 829
            + K ++ I  D+  +++ F+  +++ +  + +LN +   GI R   K I        + K
Sbjct: 600  NGKPVDEILEDIKSQLNKFKNFYNQYLSAVSYLNSVDEEGI-RNRIKEIENIVSGWNKEK 658

Query: 830  CRKQIER 850
            CR+++ +
Sbjct: 659  CREELNK 665

 Score = 33.9 bits (76), Expect = 0.62
 Identities = 48/182 (26%), Positives = 76/182 (41%), Gaps = 42/182 (23%)
 Frame = +2

Query: 299  DNIKNEVGELRE-----KELKNHEEINKLREKELKNHEEINKLRENL-QLKDEKLE---- 448
            + I+N + E+        + K  EE+NKLRE E     EIN+L++ L +LK+++ E    
Sbjct: 638  EGIRNRIKEIENIVSGWNKEKCREELNKLREDE----REINRLKDKLNELKNKEKELIEI 693

Query: 449  ----SINAXXXXXXXXXXXXXNRLKSV----EEIFNV------EIAKLKSEQEKE----- 571
                S+                 LK++    EEI+N+       I  +K +  KE     
Sbjct: 694  ENRRSLKFDKYKEYLGLTEKLEELKNIKDGLEEIYNICNSKILAIDNIKRKYNKEDIEIY 753

Query: 572  --MQSIKTEKEELDDQMRIKLRNIWYKIDEI-----------ELELKKRCESDKIESIKL 712
               + ++  KE  D + RI   N   K+DEI           EL   KR E D +   K 
Sbjct: 754  LNNKILEVNKEINDIEERISYIN--QKLDEINYNEEEHKKIKELYENKRQELDNVREQKT 811

Query: 713  DL 718
            ++
Sbjct: 812  EI 813

 Score = 32.0 bits (71), Expect = 2.4
 Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 24/197 (12%)
 Frame = +2

Query: 320 GELREKELKNHEEINKLREKELKNHE--EINKLRENLQLKDEKLESINAXXXXXXXXXXX 493
           GEL  KE    E  NK+ + E KN +  EIN     ++ + E +E +             
Sbjct: 184 GELNYKENYEKELKNKMSQLEEKNKKLMEINDKLNKIKKEFEDIEKLFNEWENKKLLYEK 243

Query: 494 XXNRL---KSVEEIFNVEIAKLKSEQEKEMQSIKTEKEELDDQMRIK-----LRNIWYKI 649
             N+L   K   E+ N E+  L+ +    +++ +T     D+  + K     +R I  ++
Sbjct: 244 FINKLEERKRALELKNQELKILEYDLNTVVEARETLNRHKDEYEKYKSLVDEIRKIESRL 303

Query: 650 DEIE------LELKKRCESDK--IESIKLDLIEK------IDVFQGNFDKKIDEIEWLNQ 787
            E++      L+L K+ E  K  IE +K + I K      ID      +K  DEIE +  
Sbjct: 304 RELKSHYEDYLKLTKQLEIIKGDIEKLK-EFINKSKYRDDIDNLDTLLNKIKDEIERVET 362

Query: 788 IGIFRTENKSIRRKCRK 838
           I     E K++  +  K
Sbjct: 363 IKDLLEELKNLNEEIEK 379
>sp|Q13439|GOGA4_HUMAN Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin)
            (Golgin-245) (Protein 72.1)
          Length = 2230

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 59/256 (23%), Positives = 116/256 (45%), Gaps = 1/256 (0%)
 Frame = +2

Query: 44   LSTVQLESRAN-NQISNLIMKCPEEMCSFECELLEMSEHLRICGKKSVECPFYKLGCDVR 220
            L  ++L+ +A   +  N +    +E  ++   +LE+   L    +KS++           
Sbjct: 537  LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSL----EKSLQ---------EN 583

Query: 221  KMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKELKNHEE 400
            K  ++ L  H + E N HNK +  M++  K E+  L+ ++     E  KL+  + +   E
Sbjct: 584  KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTE--KLQVLKQQYQTE 641

Query: 401  INKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQEKEMQS 580
            + KLRE  + + E L                    LK  E IF   I ++  +  +++  
Sbjct: 642  MEKLREKCEQEKETL--------------------LKDKEIIFQAHIEEMNEKTLEKLDV 681

Query: 581  IKTEKEELDDQMRIKLRNIWYKIDEIELELKKRCESDKIESIKLDLIEKIDVFQGNFDKK 760
             +TE E L  ++   L+   +K++E EL + K    D+ + +K +L  K+D  + +  ++
Sbjct: 682  KQTELESLSSELSEVLK-ARHKLEE-ELSVLK----DQTDKMKQELEAKMDEQKNHHQQQ 735

Query: 761  IDEIEWLNQIGIFRTE 808
            +D I   +++ I RTE
Sbjct: 736  VDSIIKEHEVSIQRTE 751

 Score = 33.9 bits (76), Expect = 0.62
 Identities = 31/141 (21%), Positives = 65/141 (46%), Gaps = 20/141 (14%)
 Frame = +2

Query: 299  DNIKNEVGELREKELKNH--------EEINKLREKELKNHEE---INKLRENLQLKDEKL 445
            + +   VG+ +E+ + +H        E + KL   E K HE+   I  L+E L+ K++K 
Sbjct: 1749 EKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKY 1808

Query: 446  ESINAXXXXXXXXXXXXXNRLKSVEEIFNV--EIAKLKSEQEKEMQSIKTEKEELDDQM- 616
              I A             N +++ + + NV  ++ K   E+E   Q ++ + +ELD  + 
Sbjct: 1809 SLIVA----QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLV 1864

Query: 617  ------RIKLRNIWYKIDEIE 661
                  R+++  +  K ++++
Sbjct: 1865 RQKEVHRVEMEELTSKYEKLQ 1885
>sp|Q59037|SMC_METJA Chromosome partition protein smc homolog
          Length = 1169

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 58/212 (27%), Positives = 103/212 (48%), Gaps = 7/212 (3%)
 Frame = +2

Query: 233  EKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINK----LREKELKNHEE 400
            EK+I   +   ++ N   +  ++ I+ E+  L +++ K   EI+K    ++E  +   EE
Sbjct: 784  EKIINELKEYESDEN---LKRMNEIEGELKILEKEKAKLKNEIDKGLTLVKEILIPKIEE 840

Query: 401  INKLRENLQLKDEKLE-SINAXXXXXXXXXXXXXNRLKSVEEIFN--VEIAKLKSEQEKE 571
            +NK    L  K   LE +I+               + K  EE+     E+ + K + EKE
Sbjct: 841  LNKKVSELINKKVILEKNISFYKESIEKNLSILEEKRKRYEELAKNLKELTEKKEQLEKE 900

Query: 572  MQSIKTEKEELDDQMRIKLRNIWYKIDEIELELKKRCESDKIESIKLDLIEKIDVFQGNF 751
            +++++ E+ E+   +R K+R+I  +I+E+ +E  K     + E  KL L EK+DV +   
Sbjct: 901  IETLERERREI---LR-KVRDIENRINELMVEKAKYESKLEEEERKLYLCEKVDVSKELE 956

Query: 752  DKKIDEIEWLNQIGIFRTENKSIRRKCRKQIE 847
             K I+E+E    IG    E KS+     + IE
Sbjct: 957  KKDIEELE--IYIGELENEIKSLEPVNMRAIE 986

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 69/299 (23%), Positives = 125/299 (41%), Gaps = 22/299 (7%)
 Frame = +2

Query: 26   DCKIELLSTVQ--------LESRANNQISNLIMKCPEEMCSFECELLEMSEHLRICGK-- 175
            + K E LS V+        L+ R NN I+ L  K  EE+      + E+   +    K  
Sbjct: 257  ELKNEFLSKVREIDVEIENLKLRLNNIINELNEKGNEEVLELHKSIKELEVEIENDKKVL 316

Query: 176  -------KSVECPFYKLGCDVRKMTNEKLIEHFQ--LENNNHNKTLIDMIDNIKNEVGEL 328
                   K VE        ++++ T +K+IE+    +E     K + + I N+  E   L
Sbjct: 317  DSSINELKKVEVEIENKKKEIKE-TQKKIIENRDSIIEKEQQIKEIEEKIKNLNYEKERL 375

Query: 329  REKELKNHEEINKLREKELKNHEEINKLRENL-QLKDEKLESINAXXXXXXXXXXXXXNR 505
            +E   ++   I  L+E E++  +EI K +  L +LK E                      
Sbjct: 376  KEAIAESESIIKHLKESEMEIADEIAKNQNELYRLKKE---------------------- 413

Query: 506  LKSVEEIFNVEIAKLKSEQEKEMQSIKTEKEELDDQMRIKLRNIWYKID--EIELELKKR 679
            L  ++ + N    +   E EK  + IK  KEEL+    +  + ++ +++   +E+E  KR
Sbjct: 414  LNDLDNLIN----RKNFEIEKNNEMIKKLKEELETVEDVDTKPLYLELENLNVEIEFSKR 469

Query: 680  CESDKIESIKLDLIEKIDVFQGNFDKKIDEIEWLNQIGIFRTENKSIRRKCRKQIERNI 856
                ++E  K +L  K+D     + K+   I+ L ++     E  S+ R  R+ +  N+
Sbjct: 470  -GIKELEEKKKELQAKLDELHAEYVKENARIKALKEM-----EELSMDRAIREILNANL 522

 Score = 32.7 bits (73), Expect = 1.4
 Identities = 47/219 (21%), Positives = 93/219 (42%), Gaps = 12/219 (5%)
 Frame = +2

Query: 17  ITNDCKIELLSTVQLESRANNQISNL---IMKCPEEMCSFECELLEMSEHLRICGKKSVE 187
           I ND K+ L S++    +   +I N    I +  +++      ++E  + ++   +K   
Sbjct: 309 IENDKKV-LDSSINELKKVEVEIENKKKEIKETQKKIIENRDSIIEKEQQIKEIEEKIKN 367

Query: 188 CPFYKLGCDVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINK 367
             + K         +E +I+H +         + D I   +NE+  L+ KEL + + +  
Sbjct: 368 LNYEKERLKEAIAESESIIKHLK----ESEMEIADEIAKNQNELYRLK-KELNDLDNLIN 422

Query: 368 LREKEL-KNHEEINKLRENLQLKDE--------KLESINAXXXXXXXXXXXXXNRLKSVE 520
            +  E+ KN+E I KL+E L+  ++        +LE++N               + K ++
Sbjct: 423 RKNFEIEKNNEMIKKLKEELETVEDVDTKPLYLELENLNVEIEFSKRGIKELEEKKKELQ 482

Query: 521 EIFNVEIAKLKSEQEKEMQSIKTEKEELDDQMRIKLRNI 637
                ++ +L +E  KE   IK  KE  +  M   +R I
Sbjct: 483 ----AKLDELHAEYVKENARIKALKEMEELSMDRAIREI 517
>sp|P30622|REST_HUMAN Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170)
            (Reed-Sternberg intermediate filament associated protein)
            (Cytoplasmic linker protein 1)
          Length = 1427

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 45/174 (25%), Positives = 82/174 (47%), Gaps = 7/174 (4%)
 Frame = +2

Query: 323  ELREKELKNHEEINKLREKELKNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXN 502
            + ++   K   E++ L+E  LKN EE+NK +E L ++++K+E                  
Sbjct: 1100 DTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQ 1159

Query: 503  RLKSVEEIFNVEIAKLKSEQEKEM---QSIKTEKEELDDQMRIKLRNIWYKIDEIELELK 673
            +L +++E  NV++A+       E+   Q ++ E+  L++Q+               LE+K
Sbjct: 1160 QLSALQE-ENVKLAEELGRSRDEVTSHQKLEEERSVLNNQL---------------LEMK 1203

Query: 674  KRCESDKIESI---KLDLIEKIDVFQGNFDKKIDEIEWL-NQIGIFRTENKSIR 823
            KR ES  I+     K  L + I +      +K  E+E L N++ + R EN S +
Sbjct: 1204 KR-ESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAK 1256

 Score = 35.4 bits (80), Expect = 0.21
 Identities = 48/215 (22%), Positives = 88/215 (40%), Gaps = 36/215 (16%)
 Frame = +2

Query: 233  EKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKELKNHEEINKL 412
            EK I+H ++E N  +     +         EL+ +ELK    +  L+E   +  +    L
Sbjct: 790  EKQIKHLEIEKNAESSKASSI-------TRELQGRELK----LTNLQENLSEVSQVKETL 838

Query: 413  RENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNV--------------EIAKL 550
             + LQ+  EK    +              N+L   EE FN+                AK 
Sbjct: 839  EKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKF 898

Query: 551  KSEQEKEMQSIKTEKE--------------------ELDDQMRIKLRNIWYKIDEIELEL 670
            + + E+E Q IK +++                    +++D++R+K R+    ++E++L+L
Sbjct: 899  REKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD----VEELQLKL 954

Query: 671  KKRCESDKI--ESIKLDLIEKIDVFQGNFDKKIDE 769
             K  E+     +SI+ D+  K +  Q    KK +E
Sbjct: 955  TKANENASFLQKSIE-DMTVKAEQSQQEAAKKHEE 988
>sp|Q9FLH0|NMCP_ARATH Putative nuclear matrix constituent protein 1-like protein
            (NMCP1-like)
          Length = 1042

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 57/229 (24%), Positives = 105/229 (45%), Gaps = 16/229 (6%)
 Frame = +2

Query: 77   NQISNLIMKCPEEMCSFECELLEM---SEHLRICGKKSVECPFYKLGCDVRKMTNEKLIE 247
            +++S L MK  EE+     + LEM   ++ L++  K   E  +  +  DV++    K  E
Sbjct: 521  SELSTLEMKLKEELDDLRAQKLEMLAEADRLKV-EKAKFEAEWEHI--DVKREELRKEAE 577

Query: 248  HFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLRE----KELKNHEE-INKL 412
            +   +    +  L D  DNIK E   LR +   + E +N+ RE    K ++ H E ++K+
Sbjct: 578  YITRQREAFSMYLKDERDNIKEERDALRNQHKNDVESLNREREEFMNKMVEEHSEWLSKI 637

Query: 413  REN-----LQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVE---IAKLKSEQEK 568
            +       L ++ +K E                 +R K+ E+   +E   I  LK   EK
Sbjct: 638  QRERADFLLGIEMQKRELEYCIENKREELENSSRDREKAFEQEKKLEEERIQSLKEMAEK 697

Query: 569  EMQSIKTEKEELDDQMRIKLRNIWYKIDEIELELKKRCESDKIESIKLD 715
            E++ ++ E + LD + R++++    + +    ELK   E  K++  KL+
Sbjct: 698  ELEHVQVELKRLDAE-RLEIKLDRERREREWAELKDSVEELKVQREKLE 745

 Score = 37.0 bits (84), Expect = 0.074
 Identities = 39/176 (22%), Positives = 83/176 (47%), Gaps = 18/176 (10%)
 Frame = +2

Query: 296  IDNIKNEVGELREKELKNHEEINKLREKELKNHEEINKLR-ENLQLK------DEKLESI 454
            ++ +K+E  EL   E+K  EE++ LR ++L+   E ++L+ E  + +      D K E +
Sbjct: 513  LEALKSETSELSTLEMKLKEELDDLRAQKLEMLAEADRLKVEKAKFEAEWEHIDVKREEL 572

Query: 455  NAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQEKEMQSIKTEKEELDDQMRIKLRN 634
                             LK   +    E   L+++ + +++S+  E+EE  ++M ++  +
Sbjct: 573  RKEAEYITRQREAFSMYLKDERDNIKEERDALRNQHKNDVESLNREREEFMNKM-VEEHS 631

Query: 635  IWY-KIDE------IELELKKR----CESDKIESIKLDLIEKIDVFQGNFDKKIDE 769
             W  KI        + +E++KR    C  +K E ++    ++   F+   +KK++E
Sbjct: 632  EWLSKIQRERADFLLGIEMQKRELEYCIENKREELENSSRDREKAFEQ--EKKLEE 685

 Score = 31.2 bits (69), Expect = 4.0
 Identities = 45/209 (21%), Positives = 87/209 (41%), Gaps = 26/209 (12%)
 Frame = +2

Query: 77   NQISNLIMKCPEEMCSFECELLEMSEHLRICGKKSVECPFYKLGCDVRKMTNEKLIEHFQ 256
            NQ  N +     E   F  +++E  EH     K   E   + LG +++K   E  IE+ +
Sbjct: 606  NQHKNDVESLNREREEFMNKMVE--EHSEWLSKIQRERADFLLGIEMQKRELEYCIENKR 663

Query: 257  LENNNHNKTLIDMIDNIKN-------EVGELREKELKNHE-----------EINKLREKE 382
             E  N ++      +  K         + E+ EKEL++ +           EI   RE+ 
Sbjct: 664  EELENSSRDREKAFEQEKKLEEERIQSLKEMAEKELEHVQVELKRLDAERLEIKLDRERR 723

Query: 383  LKNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEE----IFNVEIAKL 550
             +   E+    E L+++ EKLE+                  LK +E     + ++ +AK+
Sbjct: 724  EREWAELKDSVEELKVQREKLETQRHMLRAERDEIRHEIEELKKLENLKVALDDMSMAKM 783

Query: 551  K-SEQEKEMQSIKTEKEEL---DDQMRIK 625
            + S  E+  + +   K+++   DD++ ++
Sbjct: 784  QLSNLERSWEKVSALKQKVVSRDDELDLQ 812
>sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (TRAFAMN)
          Length = 567

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 44/212 (20%), Positives = 95/212 (44%), Gaps = 1/212 (0%)
 Frame = +2

Query: 29  CKIELLSTVQLESRANNQISNLIMKCPEEMCSFECELL-EMSEHLRICGKKSVECPFYKL 205
           CK ++   ++L+   +     +++ CP + CS +  L  E+S HL  C      C F + 
Sbjct: 179 CKSQV-PMIKLQKHEDTDCPCVVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRY 236

Query: 206 GCDVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKEL 385
           GC V + TN+++  H       H   L +  ++++ +V  L+ + ++ ++ I  L  +  
Sbjct: 237 GC-VFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQIC 295

Query: 386 KNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQE 565
               EI + +E L+  + K                     +  ++ + + +  KLK E +
Sbjct: 296 SFEIEIERQKEMLRNNESK---------------------ILHLQRVIDSQAEKLK-ELD 333

Query: 566 KEMQSIKTEKEELDDQMRIKLRNIWYKIDEIE 661
           KE++  +   EE  D M+  + ++  ++ E+E
Sbjct: 334 KEIRPFRQNWEEA-DSMKSSVESLQNRVTELE 364
>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
           associated protein) (LAP1) (CAP-1)
          Length = 568

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 44/212 (20%), Positives = 94/212 (44%), Gaps = 1/212 (0%)
 Frame = +2

Query: 29  CKIELLSTVQLESRANNQISNLIMKCPEEMCSFECELL-EMSEHLRICGKKSVECPFYKL 205
           CK ++   + L+   +     +++ CP + CS +  L  E+S HL  C      C F + 
Sbjct: 180 CKSQV-PMIALQKHEDTDCPCVVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRY 237

Query: 206 GCDVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKEL 385
           GC V + TN+++  H       H   L +  ++++ +V  L+ + ++ ++ I  L  +  
Sbjct: 238 GC-VFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQIC 296

Query: 386 KNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQE 565
               EI + +E L+  + K                     +  ++ + + +  KLK E +
Sbjct: 297 SFEIEIERQKEMLRNNESK---------------------ILHLQRVIDSQAEKLK-ELD 334

Query: 566 KEMQSIKTEKEELDDQMRIKLRNIWYKIDEIE 661
           KE++  +   EE  D M+  + ++  ++ E+E
Sbjct: 335 KEIRPFRQNWEEA-DSMKSSVESLQNRVTELE 365
>sp|Q96YR5|RAD50_SULTO DNA double-strand break repair rad50 ATPase
          Length = 879

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 53/221 (23%), Positives = 95/221 (42%), Gaps = 52/221 (23%)
 Frame = +2

Query: 212 DVRKMTNEKLIEHFQLE---NNNHNKTLIDM--IDNIKNEVGELR---EKELKNHEEINK 367
           +V    N K+IE   LE   N + N+ +     ++NIK E+ +L    EKE K +E+I K
Sbjct: 174 EVMDKINNKIIELQSLEKYKNESENQKIQKEKELENIKRELEDLNIKEEKERKKYEDIVK 233

Query: 368 LREKELKNHEE-------INKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEI 526
           L E+E K  +        +NKL++++    E+++  N               + K +EE 
Sbjct: 234 LNEEEEKKEKRYVELISLLNKLKDDISELREEVKDENRLREEKEKLEKDILEKDKLIEEK 293

Query: 527 FNVEIA----KLKSEQEKEMQSIKTEKEELDDQMRIK----------------------- 625
             +  A    KL  E+EK +++IK    +L+++++ K                       
Sbjct: 294 EKIIEAQNKIKLAQEKEKSLKTIKINLTDLEEKLKRKRELEEDYKKYIEIKGELEELEEK 353

Query: 626 ----------LRNIWYKIDEIELELKKRCESDKIESIKLDL 718
                     L+++  K+ EIE ++  R  S  IE +  +L
Sbjct: 354 ERKFNSLSDRLKSLKIKLSEIESKISNRKISINIEELDKEL 394

 Score = 37.0 bits (84), Expect = 0.074
 Identities = 45/166 (27%), Positives = 71/166 (42%), Gaps = 27/166 (16%)
 Frame = +2

Query: 218  RKMTNEKLIEHFQLE-NNNHNKTLIDMIDNIKNEVGELREKELKNHE------EINKLRE 376
            +K+  EK IE    +    +N  L   I +I+  + E++ KE K  E      +I   ++
Sbjct: 573  QKIELEKEIEEIMNKVREYYNTDLTQKIRDIEKRIQEIKGKENKLRELDTLLAKIETAKQ 632

Query: 377  KELKNHEEINKLRENLQL-----------KDEK------LESINAXXXXXXXXXXXXXNR 505
            K  +N EEI KL + LQL           K EK      L  IN+             N 
Sbjct: 633  KIKQNEEEIKKLTDELQLLNFDPNRFQQIKREKEVLEKILGEINSKKGELLGKKEVLEND 692

Query: 506  LKSVEEIFNVEIAKLKSEQE--KEMQSIKTEKEEL-DDQMRIKLRN 634
            +K +EE       KLK++Q+       +K  +E L +D+++  L N
Sbjct: 693  IKRLEEQIKDYEEKLKNKQKLITAYDKLKKLREHLAEDKLQAYLMN 738
>sp|Q66GS9|CEP4_HUMAN Centrosomal protein 4 (Centrosomal protein of 135 kDa) (Cep135
           protein)
          Length = 1140

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 45/185 (24%), Positives = 89/185 (48%), Gaps = 4/185 (2%)
 Frame = +2

Query: 203 LGCDVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKE 382
           L  + R  TNEKLI H  ++ +   +   D+   I+ E+ E +E        ++   EK 
Sbjct: 257 LSLESRNKTNEKLIAHLNIQVDFLQQANKDLEKRIR-ELMETKETVTSEVVNLSNKNEKL 315

Query: 383 LKNHEEINKLRENLQL-KDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSE 559
            +   EI++L + L+  K+E LE+ +              + ++ +EE     +AKL   
Sbjct: 316 CQELTEIDQLAQQLERHKEELLETADKELGEAKKEIKRKLSEMQDLEE----TMAKL--- 368

Query: 560 QEKEMQSIKTEKEELDDQMRIK--LRNIWYKIDEIELELKKRCESDKIESIKLDL-IEKI 730
            + E+   + EKE L D++ +K  L  + +++++ +  L K+ ES  +   +L L +E++
Sbjct: 369 -QLELNLCQKEKERLSDELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVERM 427

Query: 731 DVFQG 745
            +  G
Sbjct: 428 RLEHG 432

 Score = 31.2 bits (69), Expect = 4.0
 Identities = 40/199 (20%), Positives = 86/199 (43%), Gaps = 26/199 (13%)
 Frame = +2

Query: 215  VRKMTNEKLIEHFQLENNNHNKT-----LIDMIDNIKNEVGELREKELKNHEEINKLREK 379
            +++  +EK  +   L+ N  NK      +  MI   ++ V +L+E  +    EIN LR +
Sbjct: 739  LQETVDEKTEKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQ 798

Query: 380  ELKNHEEINKL--------RENLQLKDE--KLESINAXXXXXXXXXXXXXNRLKSVEEIF 529
                H+E++++        +EN +L+D+   +   N                +KS    +
Sbjct: 799  LDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQEISLELEAAVQEKEEMKSRVHKY 858

Query: 530  NVEIAK---LKSEQEKEMQSIKTEKEELD---DQMRIKLRNIWYKIDEIELEL-----KK 676
              E+++   L + +EKE Q +    + L    +   +K      +   + LEL     ++
Sbjct: 859  ITEVSRWESLMAAKEKENQDLLDRFQMLHNRAEDWEVKAHQAEGESSSVRLELLSIDTER 918

Query: 677  RCESDKIESIKLDLIEKID 733
            R   +++E ++ ++ E I+
Sbjct: 919  RHLRERVELLEKEIQEHIN 937
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,015,108
Number of Sequences: 369166
Number of extensions: 1467079
Number of successful extensions: 7919
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6711
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7647
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8886314050
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)