Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_E10
(888 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O42184|REST_CHICK Restin (Cytoplasmic linker protein 170... 57 5e-08
sp|Q58718|RAD50_METJA DNA double-strand break repair rad50 ... 56 1e-07
sp|Q13439|GOGA4_HUMAN Golgin subfamily A member 4 (Trans-Go... 55 3e-07
sp|Q59037|SMC_METJA Chromosome partition protein smc homolog 50 6e-06
sp|P30622|REST_HUMAN Restin (Cytoplasmic linker protein 170... 49 1e-05
sp|Q9FLH0|NMCP_ARATH Putative nuclear matrix constituent pr... 49 1e-05
sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD4... 49 2e-05
sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD4... 48 4e-05
sp|Q96YR5|RAD50_SULTO DNA double-strand break repair rad50 ... 48 4e-05
sp|Q66GS9|CEP4_HUMAN Centrosomal protein 4 (Centrosomal pro... 47 5e-05
>sp|O42184|REST_CHICK Restin (Cytoplasmic linker protein 170) (CLIP-170)
Length = 1433
Score = 57.4 bits (137), Expect = 5e-08
Identities = 62/265 (23%), Positives = 119/265 (44%), Gaps = 10/265 (3%)
Frame = +2
Query: 59 LESRANNQISNLIMKCPEEMCSFECELLEMSEHLRICGKKSVECPFY---------KLGC 211
L+++ + S +I K ++ F+ LL+ E L+ KK+ E +
Sbjct: 1009 LQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKA 1068
Query: 212 DVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKELKN 391
D R + +E E + ++ I+ + +++N R+ K E++ L++ LKN
Sbjct: 1069 DKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENS----RQTNEKLQNELDMLKQNNLKN 1124
Query: 392 HEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQEKE 571
EE+ K +E L L+++K+E + +L +++E NV++A+ E
Sbjct: 1125 EEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQE-ENVKLAEELGRSRDE 1183
Query: 572 MQSIKTEKEELDDQMRIKLRNIWYKIDEIELELKKRCESDKIESIKLDLIEKIDVFQGNF 751
+ S + +EE R L N ++ + E LKK +I+ + L + I
Sbjct: 1184 VTSHQKLEEE-----RSVLNNQLLEMKKRESTLKK-----EIDEERASLQKSISDTSALI 1233
Query: 752 DKKIDEIEWL-NQIGIFRTENKSIR 823
+K +E+E L N+I + R EN S +
Sbjct: 1234 TQKDEELEKLRNEITVLRGENASAK 1258
>sp|Q58718|RAD50_METJA DNA double-strand break repair rad50 ATPase
Length = 1005
Score = 56.2 bits (134), Expect = 1e-07
Identities = 62/247 (25%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Frame = +2
Query: 173 KKSVECPFYKLGCDVRKMTNE-KLIEHFQLENN-NHNKTLIDMIDNIKNEVGELREKELK 346
KKS+E L + K+ E K I+ +EN+ + +++N++ E EL +K +
Sbjct: 421 KKSIEKNINDLETRINKLLEETKNIDIESIENSLKEIEEKKKVLENLQKEKIELNKKLGE 480
Query: 347 NHEEINKLRE--KELKNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVE 520
+ EI +L++ ELK E L + +++K+E IN K +
Sbjct: 481 INSEIKRLKKILDELKEVEGKCPLCKTPIDENKKMELINQHKTQLNNKYTELEEINKKIR 540
Query: 521 EIFNVEIAKLKSEQEKE--MQSIKT---EKEELDDQMRIKLRNIWYKIDEIELELKKRCE 685
EI +I KLK E +KE ++++KT EK+ +++ +KL+N ++DEI ++
Sbjct: 541 EI-EKDIEKLKKEIDKEENLKTLKTLYLEKQSQIEELELKLKNYKEQLDEINKKISNYVI 599
Query: 686 SDK-IESIKLDLIEKIDVFQGNFDKKIDEIEWLNQI---GIFRTENKSI--------RRK 829
+ K ++ I D+ +++ F+ +++ + + +LN + GI R K I + K
Sbjct: 600 NGKPVDEILEDIKSQLNKFKNFYNQYLSAVSYLNSVDEEGI-RNRIKEIENIVSGWNKEK 658
Query: 830 CRKQIER 850
CR+++ +
Sbjct: 659 CREELNK 665
Score = 33.9 bits (76), Expect = 0.62
Identities = 48/182 (26%), Positives = 76/182 (41%), Gaps = 42/182 (23%)
Frame = +2
Query: 299 DNIKNEVGELRE-----KELKNHEEINKLREKELKNHEEINKLRENL-QLKDEKLE---- 448
+ I+N + E+ + K EE+NKLRE E EIN+L++ L +LK+++ E
Sbjct: 638 EGIRNRIKEIENIVSGWNKEKCREELNKLREDE----REINRLKDKLNELKNKEKELIEI 693
Query: 449 ----SINAXXXXXXXXXXXXXNRLKSV----EEIFNV------EIAKLKSEQEKE----- 571
S+ LK++ EEI+N+ I +K + KE
Sbjct: 694 ENRRSLKFDKYKEYLGLTEKLEELKNIKDGLEEIYNICNSKILAIDNIKRKYNKEDIEIY 753
Query: 572 --MQSIKTEKEELDDQMRIKLRNIWYKIDEI-----------ELELKKRCESDKIESIKL 712
+ ++ KE D + RI N K+DEI EL KR E D + K
Sbjct: 754 LNNKILEVNKEINDIEERISYIN--QKLDEINYNEEEHKKIKELYENKRQELDNVREQKT 811
Query: 713 DL 718
++
Sbjct: 812 EI 813
Score = 32.0 bits (71), Expect = 2.4
Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 24/197 (12%)
Frame = +2
Query: 320 GELREKELKNHEEINKLREKELKNHE--EINKLRENLQLKDEKLESINAXXXXXXXXXXX 493
GEL KE E NK+ + E KN + EIN ++ + E +E +
Sbjct: 184 GELNYKENYEKELKNKMSQLEEKNKKLMEINDKLNKIKKEFEDIEKLFNEWENKKLLYEK 243
Query: 494 XXNRL---KSVEEIFNVEIAKLKSEQEKEMQSIKTEKEELDDQMRIK-----LRNIWYKI 649
N+L K E+ N E+ L+ + +++ +T D+ + K +R I ++
Sbjct: 244 FINKLEERKRALELKNQELKILEYDLNTVVEARETLNRHKDEYEKYKSLVDEIRKIESRL 303
Query: 650 DEIE------LELKKRCESDK--IESIKLDLIEK------IDVFQGNFDKKIDEIEWLNQ 787
E++ L+L K+ E K IE +K + I K ID +K DEIE +
Sbjct: 304 RELKSHYEDYLKLTKQLEIIKGDIEKLK-EFINKSKYRDDIDNLDTLLNKIKDEIERVET 362
Query: 788 IGIFRTENKSIRRKCRK 838
I E K++ + K
Sbjct: 363 IKDLLEELKNLNEEIEK 379
>sp|Q13439|GOGA4_HUMAN Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin)
(Golgin-245) (Protein 72.1)
Length = 2230
Score = 55.1 bits (131), Expect = 3e-07
Identities = 59/256 (23%), Positives = 116/256 (45%), Gaps = 1/256 (0%)
Frame = +2
Query: 44 LSTVQLESRAN-NQISNLIMKCPEEMCSFECELLEMSEHLRICGKKSVECPFYKLGCDVR 220
L ++L+ +A + N + +E ++ +LE+ L +KS++
Sbjct: 537 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSL----EKSLQ---------EN 583
Query: 221 KMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKELKNHEE 400
K ++ L H + E N HNK + M++ K E+ L+ ++ E KL+ + + E
Sbjct: 584 KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTE--KLQVLKQQYQTE 641
Query: 401 INKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQEKEMQS 580
+ KLRE + + E L LK E IF I ++ + +++
Sbjct: 642 MEKLREKCEQEKETL--------------------LKDKEIIFQAHIEEMNEKTLEKLDV 681
Query: 581 IKTEKEELDDQMRIKLRNIWYKIDEIELELKKRCESDKIESIKLDLIEKIDVFQGNFDKK 760
+TE E L ++ L+ +K++E EL + K D+ + +K +L K+D + + ++
Sbjct: 682 KQTELESLSSELSEVLK-ARHKLEE-ELSVLK----DQTDKMKQELEAKMDEQKNHHQQQ 735
Query: 761 IDEIEWLNQIGIFRTE 808
+D I +++ I RTE
Sbjct: 736 VDSIIKEHEVSIQRTE 751
Score = 33.9 bits (76), Expect = 0.62
Identities = 31/141 (21%), Positives = 65/141 (46%), Gaps = 20/141 (14%)
Frame = +2
Query: 299 DNIKNEVGELREKELKNH--------EEINKLREKELKNHEE---INKLRENLQLKDEKL 445
+ + VG+ +E+ + +H E + KL E K HE+ I L+E L+ K++K
Sbjct: 1749 EKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKY 1808
Query: 446 ESINAXXXXXXXXXXXXXNRLKSVEEIFNV--EIAKLKSEQEKEMQSIKTEKEELDDQM- 616
I A N +++ + + NV ++ K E+E Q ++ + +ELD +
Sbjct: 1809 SLIVA----QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLV 1864
Query: 617 ------RIKLRNIWYKIDEIE 661
R+++ + K ++++
Sbjct: 1865 RQKEVHRVEMEELTSKYEKLQ 1885
>sp|Q59037|SMC_METJA Chromosome partition protein smc homolog
Length = 1169
Score = 50.4 bits (119), Expect = 6e-06
Identities = 58/212 (27%), Positives = 103/212 (48%), Gaps = 7/212 (3%)
Frame = +2
Query: 233 EKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINK----LREKELKNHEE 400
EK+I + ++ N + ++ I+ E+ L +++ K EI+K ++E + EE
Sbjct: 784 EKIINELKEYESDEN---LKRMNEIEGELKILEKEKAKLKNEIDKGLTLVKEILIPKIEE 840
Query: 401 INKLRENLQLKDEKLE-SINAXXXXXXXXXXXXXNRLKSVEEIFN--VEIAKLKSEQEKE 571
+NK L K LE +I+ + K EE+ E+ + K + EKE
Sbjct: 841 LNKKVSELINKKVILEKNISFYKESIEKNLSILEEKRKRYEELAKNLKELTEKKEQLEKE 900
Query: 572 MQSIKTEKEELDDQMRIKLRNIWYKIDEIELELKKRCESDKIESIKLDLIEKIDVFQGNF 751
+++++ E+ E+ +R K+R+I +I+E+ +E K + E KL L EK+DV +
Sbjct: 901 IETLERERREI---LR-KVRDIENRINELMVEKAKYESKLEEEERKLYLCEKVDVSKELE 956
Query: 752 DKKIDEIEWLNQIGIFRTENKSIRRKCRKQIE 847
K I+E+E IG E KS+ + IE
Sbjct: 957 KKDIEELE--IYIGELENEIKSLEPVNMRAIE 986
Score = 47.4 bits (111), Expect = 5e-05
Identities = 69/299 (23%), Positives = 125/299 (41%), Gaps = 22/299 (7%)
Frame = +2
Query: 26 DCKIELLSTVQ--------LESRANNQISNLIMKCPEEMCSFECELLEMSEHLRICGK-- 175
+ K E LS V+ L+ R NN I+ L K EE+ + E+ + K
Sbjct: 257 ELKNEFLSKVREIDVEIENLKLRLNNIINELNEKGNEEVLELHKSIKELEVEIENDKKVL 316
Query: 176 -------KSVECPFYKLGCDVRKMTNEKLIEHFQ--LENNNHNKTLIDMIDNIKNEVGEL 328
K VE ++++ T +K+IE+ +E K + + I N+ E L
Sbjct: 317 DSSINELKKVEVEIENKKKEIKE-TQKKIIENRDSIIEKEQQIKEIEEKIKNLNYEKERL 375
Query: 329 REKELKNHEEINKLREKELKNHEEINKLRENL-QLKDEKLESINAXXXXXXXXXXXXXNR 505
+E ++ I L+E E++ +EI K + L +LK E
Sbjct: 376 KEAIAESESIIKHLKESEMEIADEIAKNQNELYRLKKE---------------------- 413
Query: 506 LKSVEEIFNVEIAKLKSEQEKEMQSIKTEKEELDDQMRIKLRNIWYKID--EIELELKKR 679
L ++ + N + E EK + IK KEEL+ + + ++ +++ +E+E KR
Sbjct: 414 LNDLDNLIN----RKNFEIEKNNEMIKKLKEELETVEDVDTKPLYLELENLNVEIEFSKR 469
Query: 680 CESDKIESIKLDLIEKIDVFQGNFDKKIDEIEWLNQIGIFRTENKSIRRKCRKQIERNI 856
++E K +L K+D + K+ I+ L ++ E S+ R R+ + N+
Sbjct: 470 -GIKELEEKKKELQAKLDELHAEYVKENARIKALKEM-----EELSMDRAIREILNANL 522
Score = 32.7 bits (73), Expect = 1.4
Identities = 47/219 (21%), Positives = 93/219 (42%), Gaps = 12/219 (5%)
Frame = +2
Query: 17 ITNDCKIELLSTVQLESRANNQISNL---IMKCPEEMCSFECELLEMSEHLRICGKKSVE 187
I ND K+ L S++ + +I N I + +++ ++E + ++ +K
Sbjct: 309 IENDKKV-LDSSINELKKVEVEIENKKKEIKETQKKIIENRDSIIEKEQQIKEIEEKIKN 367
Query: 188 CPFYKLGCDVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINK 367
+ K +E +I+H + + D I +NE+ L+ KEL + + +
Sbjct: 368 LNYEKERLKEAIAESESIIKHLK----ESEMEIADEIAKNQNELYRLK-KELNDLDNLIN 422
Query: 368 LREKEL-KNHEEINKLRENLQLKDE--------KLESINAXXXXXXXXXXXXXNRLKSVE 520
+ E+ KN+E I KL+E L+ ++ +LE++N + K ++
Sbjct: 423 RKNFEIEKNNEMIKKLKEELETVEDVDTKPLYLELENLNVEIEFSKRGIKELEEKKKELQ 482
Query: 521 EIFNVEIAKLKSEQEKEMQSIKTEKEELDDQMRIKLRNI 637
++ +L +E KE IK KE + M +R I
Sbjct: 483 ----AKLDELHAEYVKENARIKALKEMEELSMDRAIREI 517
>sp|P30622|REST_HUMAN Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170)
(Reed-Sternberg intermediate filament associated protein)
(Cytoplasmic linker protein 1)
Length = 1427
Score = 49.3 bits (116), Expect = 1e-05
Identities = 45/174 (25%), Positives = 82/174 (47%), Gaps = 7/174 (4%)
Frame = +2
Query: 323 ELREKELKNHEEINKLREKELKNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXN 502
+ ++ K E++ L+E LKN EE+NK +E L ++++K+E
Sbjct: 1100 DTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQ 1159
Query: 503 RLKSVEEIFNVEIAKLKSEQEKEM---QSIKTEKEELDDQMRIKLRNIWYKIDEIELELK 673
+L +++E NV++A+ E+ Q ++ E+ L++Q+ LE+K
Sbjct: 1160 QLSALQE-ENVKLAEELGRSRDEVTSHQKLEEERSVLNNQL---------------LEMK 1203
Query: 674 KRCESDKIESI---KLDLIEKIDVFQGNFDKKIDEIEWL-NQIGIFRTENKSIR 823
KR ES I+ K L + I + +K E+E L N++ + R EN S +
Sbjct: 1204 KR-ESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAK 1256
Score = 35.4 bits (80), Expect = 0.21
Identities = 48/215 (22%), Positives = 88/215 (40%), Gaps = 36/215 (16%)
Frame = +2
Query: 233 EKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKELKNHEEINKL 412
EK I+H ++E N + + EL+ +ELK + L+E + + L
Sbjct: 790 EKQIKHLEIEKNAESSKASSI-------TRELQGRELK----LTNLQENLSEVSQVKETL 838
Query: 413 RENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNV--------------EIAKL 550
+ LQ+ EK + N+L EE FN+ AK
Sbjct: 839 EKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKF 898
Query: 551 KSEQEKEMQSIKTEKE--------------------ELDDQMRIKLRNIWYKIDEIELEL 670
+ + E+E Q IK +++ +++D++R+K R+ ++E++L+L
Sbjct: 899 REKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD----VEELQLKL 954
Query: 671 KKRCESDKI--ESIKLDLIEKIDVFQGNFDKKIDE 769
K E+ +SI+ D+ K + Q KK +E
Sbjct: 955 TKANENASFLQKSIE-DMTVKAEQSQQEAAKKHEE 988
>sp|Q9FLH0|NMCP_ARATH Putative nuclear matrix constituent protein 1-like protein
(NMCP1-like)
Length = 1042
Score = 49.3 bits (116), Expect = 1e-05
Identities = 57/229 (24%), Positives = 105/229 (45%), Gaps = 16/229 (6%)
Frame = +2
Query: 77 NQISNLIMKCPEEMCSFECELLEM---SEHLRICGKKSVECPFYKLGCDVRKMTNEKLIE 247
+++S L MK EE+ + LEM ++ L++ K E + + DV++ K E
Sbjct: 521 SELSTLEMKLKEELDDLRAQKLEMLAEADRLKV-EKAKFEAEWEHI--DVKREELRKEAE 577
Query: 248 HFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLRE----KELKNHEE-INKL 412
+ + + L D DNIK E LR + + E +N+ RE K ++ H E ++K+
Sbjct: 578 YITRQREAFSMYLKDERDNIKEERDALRNQHKNDVESLNREREEFMNKMVEEHSEWLSKI 637
Query: 413 REN-----LQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVE---IAKLKSEQEK 568
+ L ++ +K E +R K+ E+ +E I LK EK
Sbjct: 638 QRERADFLLGIEMQKRELEYCIENKREELENSSRDREKAFEQEKKLEEERIQSLKEMAEK 697
Query: 569 EMQSIKTEKEELDDQMRIKLRNIWYKIDEIELELKKRCESDKIESIKLD 715
E++ ++ E + LD + R++++ + + ELK E K++ KL+
Sbjct: 698 ELEHVQVELKRLDAE-RLEIKLDRERREREWAELKDSVEELKVQREKLE 745
Score = 37.0 bits (84), Expect = 0.074
Identities = 39/176 (22%), Positives = 83/176 (47%), Gaps = 18/176 (10%)
Frame = +2
Query: 296 IDNIKNEVGELREKELKNHEEINKLREKELKNHEEINKLR-ENLQLK------DEKLESI 454
++ +K+E EL E+K EE++ LR ++L+ E ++L+ E + + D K E +
Sbjct: 513 LEALKSETSELSTLEMKLKEELDDLRAQKLEMLAEADRLKVEKAKFEAEWEHIDVKREEL 572
Query: 455 NAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQEKEMQSIKTEKEELDDQMRIKLRN 634
LK + E L+++ + +++S+ E+EE ++M ++ +
Sbjct: 573 RKEAEYITRQREAFSMYLKDERDNIKEERDALRNQHKNDVESLNREREEFMNKM-VEEHS 631
Query: 635 IWY-KIDE------IELELKKR----CESDKIESIKLDLIEKIDVFQGNFDKKIDE 769
W KI + +E++KR C +K E ++ ++ F+ +KK++E
Sbjct: 632 EWLSKIQRERADFLLGIEMQKRELEYCIENKREELENSSRDREKAFEQ--EKKLEE 685
Score = 31.2 bits (69), Expect = 4.0
Identities = 45/209 (21%), Positives = 87/209 (41%), Gaps = 26/209 (12%)
Frame = +2
Query: 77 NQISNLIMKCPEEMCSFECELLEMSEHLRICGKKSVECPFYKLGCDVRKMTNEKLIEHFQ 256
NQ N + E F +++E EH K E + LG +++K E IE+ +
Sbjct: 606 NQHKNDVESLNREREEFMNKMVE--EHSEWLSKIQRERADFLLGIEMQKRELEYCIENKR 663
Query: 257 LENNNHNKTLIDMIDNIKN-------EVGELREKELKNHE-----------EINKLREKE 382
E N ++ + K + E+ EKEL++ + EI RE+
Sbjct: 664 EELENSSRDREKAFEQEKKLEEERIQSLKEMAEKELEHVQVELKRLDAERLEIKLDRERR 723
Query: 383 LKNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEE----IFNVEIAKL 550
+ E+ E L+++ EKLE+ LK +E + ++ +AK+
Sbjct: 724 EREWAELKDSVEELKVQREKLETQRHMLRAERDEIRHEIEELKKLENLKVALDDMSMAKM 783
Query: 551 K-SEQEKEMQSIKTEKEEL---DDQMRIK 625
+ S E+ + + K+++ DD++ ++
Sbjct: 784 QLSNLERSWEKVSALKQKVVSRDDELDLQ 812
>sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD40 receptor associated factor
1) (CRAF1) (TRAFAMN)
Length = 567
Score = 48.5 bits (114), Expect = 2e-05
Identities = 44/212 (20%), Positives = 95/212 (44%), Gaps = 1/212 (0%)
Frame = +2
Query: 29 CKIELLSTVQLESRANNQISNLIMKCPEEMCSFECELL-EMSEHLRICGKKSVECPFYKL 205
CK ++ ++L+ + +++ CP + CS + L E+S HL C C F +
Sbjct: 179 CKSQV-PMIKLQKHEDTDCPCVVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRY 236
Query: 206 GCDVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKEL 385
GC V + TN+++ H H L + ++++ +V L+ + ++ ++ I L +
Sbjct: 237 GC-VFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQIC 295
Query: 386 KNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQE 565
EI + +E L+ + K + ++ + + + KLK E +
Sbjct: 296 SFEIEIERQKEMLRNNESK---------------------ILHLQRVIDSQAEKLK-ELD 333
Query: 566 KEMQSIKTEKEELDDQMRIKLRNIWYKIDEIE 661
KE++ + EE D M+ + ++ ++ E+E
Sbjct: 334 KEIRPFRQNWEEA-DSMKSSVESLQNRVTELE 364
>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
associated protein) (LAP1) (CAP-1)
Length = 568
Score = 47.8 bits (112), Expect = 4e-05
Identities = 44/212 (20%), Positives = 94/212 (44%), Gaps = 1/212 (0%)
Frame = +2
Query: 29 CKIELLSTVQLESRANNQISNLIMKCPEEMCSFECELL-EMSEHLRICGKKSVECPFYKL 205
CK ++ + L+ + +++ CP + CS + L E+S HL C C F +
Sbjct: 180 CKSQV-PMIALQKHEDTDCPCVVVSCPHK-CSVQTLLRSELSAHLSECVNAPSTCSFKRY 237
Query: 206 GCDVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKEL 385
GC V + TN+++ H H L + ++++ +V L+ + ++ ++ I L +
Sbjct: 238 GC-VFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQIC 296
Query: 386 KNHEEINKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSEQE 565
EI + +E L+ + K + ++ + + + KLK E +
Sbjct: 297 SFEIEIERQKEMLRNNESK---------------------ILHLQRVIDSQAEKLK-ELD 334
Query: 566 KEMQSIKTEKEELDDQMRIKLRNIWYKIDEIE 661
KE++ + EE D M+ + ++ ++ E+E
Sbjct: 335 KEIRPFRQNWEEA-DSMKSSVESLQNRVTELE 365
>sp|Q96YR5|RAD50_SULTO DNA double-strand break repair rad50 ATPase
Length = 879
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/221 (23%), Positives = 95/221 (42%), Gaps = 52/221 (23%)
Frame = +2
Query: 212 DVRKMTNEKLIEHFQLE---NNNHNKTLIDM--IDNIKNEVGELR---EKELKNHEEINK 367
+V N K+IE LE N + N+ + ++NIK E+ +L EKE K +E+I K
Sbjct: 174 EVMDKINNKIIELQSLEKYKNESENQKIQKEKELENIKRELEDLNIKEEKERKKYEDIVK 233
Query: 368 LREKELKNHEE-------INKLRENLQLKDEKLESINAXXXXXXXXXXXXXNRLKSVEEI 526
L E+E K + +NKL++++ E+++ N + K +EE
Sbjct: 234 LNEEEEKKEKRYVELISLLNKLKDDISELREEVKDENRLREEKEKLEKDILEKDKLIEEK 293
Query: 527 FNVEIA----KLKSEQEKEMQSIKTEKEELDDQMRIK----------------------- 625
+ A KL E+EK +++IK +L+++++ K
Sbjct: 294 EKIIEAQNKIKLAQEKEKSLKTIKINLTDLEEKLKRKRELEEDYKKYIEIKGELEELEEK 353
Query: 626 ----------LRNIWYKIDEIELELKKRCESDKIESIKLDL 718
L+++ K+ EIE ++ R S IE + +L
Sbjct: 354 ERKFNSLSDRLKSLKIKLSEIESKISNRKISINIEELDKEL 394
Score = 37.0 bits (84), Expect = 0.074
Identities = 45/166 (27%), Positives = 71/166 (42%), Gaps = 27/166 (16%)
Frame = +2
Query: 218 RKMTNEKLIEHFQLE-NNNHNKTLIDMIDNIKNEVGELREKELKNHE------EINKLRE 376
+K+ EK IE + +N L I +I+ + E++ KE K E +I ++
Sbjct: 573 QKIELEKEIEEIMNKVREYYNTDLTQKIRDIEKRIQEIKGKENKLRELDTLLAKIETAKQ 632
Query: 377 KELKNHEEINKLRENLQL-----------KDEK------LESINAXXXXXXXXXXXXXNR 505
K +N EEI KL + LQL K EK L IN+ N
Sbjct: 633 KIKQNEEEIKKLTDELQLLNFDPNRFQQIKREKEVLEKILGEINSKKGELLGKKEVLEND 692
Query: 506 LKSVEEIFNVEIAKLKSEQE--KEMQSIKTEKEEL-DDQMRIKLRN 634
+K +EE KLK++Q+ +K +E L +D+++ L N
Sbjct: 693 IKRLEEQIKDYEEKLKNKQKLITAYDKLKKLREHLAEDKLQAYLMN 738
>sp|Q66GS9|CEP4_HUMAN Centrosomal protein 4 (Centrosomal protein of 135 kDa) (Cep135
protein)
Length = 1140
Score = 47.4 bits (111), Expect = 5e-05
Identities = 45/185 (24%), Positives = 89/185 (48%), Gaps = 4/185 (2%)
Frame = +2
Query: 203 LGCDVRKMTNEKLIEHFQLENNNHNKTLIDMIDNIKNEVGELREKELKNHEEINKLREKE 382
L + R TNEKLI H ++ + + D+ I+ E+ E +E ++ EK
Sbjct: 257 LSLESRNKTNEKLIAHLNIQVDFLQQANKDLEKRIR-ELMETKETVTSEVVNLSNKNEKL 315
Query: 383 LKNHEEINKLRENLQL-KDEKLESINAXXXXXXXXXXXXXNRLKSVEEIFNVEIAKLKSE 559
+ EI++L + L+ K+E LE+ + + ++ +EE +AKL
Sbjct: 316 CQELTEIDQLAQQLERHKEELLETADKELGEAKKEIKRKLSEMQDLEE----TMAKL--- 368
Query: 560 QEKEMQSIKTEKEELDDQMRIK--LRNIWYKIDEIELELKKRCESDKIESIKLDL-IEKI 730
+ E+ + EKE L D++ +K L + +++++ + L K+ ES + +L L +E++
Sbjct: 369 -QLELNLCQKEKERLSDELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVERM 427
Query: 731 DVFQG 745
+ G
Sbjct: 428 RLEHG 432
Score = 31.2 bits (69), Expect = 4.0
Identities = 40/199 (20%), Positives = 86/199 (43%), Gaps = 26/199 (13%)
Frame = +2
Query: 215 VRKMTNEKLIEHFQLENNNHNKT-----LIDMIDNIKNEVGELREKELKNHEEINKLREK 379
+++ +EK + L+ N NK + MI ++ V +L+E + EIN LR +
Sbjct: 739 LQETVDEKTEKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQ 798
Query: 380 ELKNHEEINKL--------RENLQLKDE--KLESINAXXXXXXXXXXXXXNRLKSVEEIF 529
H+E++++ +EN +L+D+ + N +KS +
Sbjct: 799 LDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQEISLELEAAVQEKEEMKSRVHKY 858
Query: 530 NVEIAK---LKSEQEKEMQSIKTEKEELD---DQMRIKLRNIWYKIDEIELEL-----KK 676
E+++ L + +EKE Q + + L + +K + + LEL ++
Sbjct: 859 ITEVSRWESLMAAKEKENQDLLDRFQMLHNRAEDWEVKAHQAEGESSSVRLELLSIDTER 918
Query: 677 RCESDKIESIKLDLIEKID 733
R +++E ++ ++ E I+
Sbjct: 919 RHLRERVELLEKEIQEHIN 937
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,015,108
Number of Sequences: 369166
Number of extensions: 1467079
Number of successful extensions: 7919
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6711
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7647
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8886314050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)