Planaria EST Database


DrC_02736

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02736
         (811 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P54813|YME1_CAEEL  YME1 protein homolog                        172   1e-42
sp|O88967|YMEL1_MOUSE  ATP-dependent metalloprotease YME1L1 ...   164   2e-40
sp|Q96TA2|YMEL1_HUMAN  ATP-dependent metalloprotease YME1L1 ...   163   5e-40
sp|Q925S8|YMEL1_RAT  ATP-dependent metalloprotease YME1L1 (Y...   163   5e-40
sp|P46508|YME1_SCHMA  YME1 protein homolog                        142   1e-33
sp|P94304|FTSH_BACPF  Cell division protein ftsH homolog          139   7e-33
sp|P32795|YME1_YEAST  YME1 protein (TAT-binding homolog 11) ...   139   9e-33
sp|Q98PE4|FTSH_MYCPU  Cell division protein ftsH homolog          137   3e-32
sp|P37476|FTSH_BACSU  Cell division protein ftsH homolog          130   4e-30
sp|Q89AF2|FTSH_BUCBP  Cell division protein ftsH                  130   4e-30
>sp|P54813|YME1_CAEEL YME1 protein homolog
          Length = 676

 Score =  172 bits (435), Expect = 1e-42
 Identities = 95/239 (39%), Positives = 155/239 (64%), Gaps = 10/239 (4%)
 Frame = +2

Query: 2    VSMDHIWEAESKILMGSVRNKPSLVSE--NRNTAFHESGHCIVGYFTPNHPGKIKQITIL 175
            V+M ++ EA  ++LMG  R    +  E  NRNTA+HE+GH +V  +T +    + ++TI+
Sbjct: 427  VTMAYLDEARDRVLMGPARTGGRIPDEEANRNTAYHEAGHTLVSLYTKDAT-PLHKVTII 485

Query: 176  PRGNSGGHSSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRAT 355
            PRG S GH++++P++DSY ++K Q+LA +D +MGGR AEEL+ G D ++TG  DDL +AT
Sbjct: 486  PRGQSLGHTAMLPEKDSYQLTKAQMLATLDVMMGGRVAEELIFGDDKVTTGAADDLSKAT 545

Query: 356  KYARSMVMSYSMSEDVGLQ--TISDGNCS-CGGRPLSGKLADTIDIEVNKILKESYERAK 526
            + A  MV  + MS+ VGL+  T  D   +      L+ + A+ ID E+N++L+ESY+RAK
Sbjct: 546  QLAVQMVKVFGMSDKVGLRDFTAQDNESALVKVSDLAPQTAELIDAEINRVLQESYKRAK 605

Query: 527  SLIQQHEKEWNAIATYLLKYETLKHEDIELIIQG---KKPKVAIIHE--EIQKNKKSFV 688
             +++  +KE   +A  LL+YETL  ++++ +I G   K+P  A + +  E ++N+ S V
Sbjct: 606  VILETKKKEHQLLAEALLEYETLSADEVKRVISGQKIKRPTPAAVKKSNETKRNQPSLV 664
>sp|O88967|YMEL1_MOUSE ATP-dependent metalloprotease YME1L1 (YME1-like protein 1)
            (ATP-dependent metalloprotease FtsH1)
          Length = 715

 Score =  164 bits (416), Expect = 2e-40
 Identities = 91/215 (42%), Positives = 137/215 (63%), Gaps = 1/215 (0%)
 Frame = +2

Query: 2    VSMDHIWEAESKILMGSVRNKPSLVSENRN-TAFHESGHCIVGYFTPNHPGKIKQITILP 178
            V+M  +  ++ KILMG  R    + ++N+  TA+HESGH I+ Y+T +    I + TI+P
Sbjct: 507  VTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAM-PINKATIMP 565

Query: 179  RGNSGGHSSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRATK 358
            RG + GH SL+P+ D +N ++ QLLA +D  MGGR AEEL+ G+D+I+TG   D   ATK
Sbjct: 566  RGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATK 625

Query: 359  YARSMVMSYSMSEDVGLQTISDGNCSCGGRPLSGKLADTIDIEVNKILKESYERAKSLIQ 538
             A+ MV  + MSE +G+ T SD         LS +    I+ E+  +L+ESYERAK +++
Sbjct: 626  IAKRMVTKFGMSEKLGVMTYSDTG------KLSPETQSAIEQEIRILLRESYERAKHILK 679

Query: 539  QHEKEWNAIATYLLKYETLKHEDIELIIQGKKPKV 643
             H KE   +A  LL YETL  ++I+++++GKK +V
Sbjct: 680  THAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEV 714
>sp|Q96TA2|YMEL1_HUMAN ATP-dependent metalloprotease YME1L1 (YME1-like protein 1)
            (ATP-dependent metalloprotease FtsH1) (Meg-4)
            (Presenilin-associated metalloprotease) (PAMP)
          Length = 773

 Score =  163 bits (413), Expect = 5e-40
 Identities = 90/215 (41%), Positives = 137/215 (63%), Gaps = 1/215 (0%)
 Frame = +2

Query: 2    VSMDHIWEAESKILMGSVRNKPSLVSENRN-TAFHESGHCIVGYFTPNHPGKIKQITILP 178
            V+M  +  ++ KILMG  R    + ++N+  TA+HESGH I+ Y+T +    I + TI+P
Sbjct: 565  VTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAM-PINKATIMP 623

Query: 179  RGNSGGHSSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRATK 358
            RG + GH SL+P+ D +N ++ QLLA +D  MGGR AEEL+ G+D+I+TG   D   ATK
Sbjct: 624  RGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATK 683

Query: 359  YARSMVMSYSMSEDVGLQTISDGNCSCGGRPLSGKLADTIDIEVNKILKESYERAKSLIQ 538
             A+ MV  + MSE +G+ T SD         LS +    I+ E+  +L++SYERAK +++
Sbjct: 684  IAKRMVTKFGMSEKLGVMTYSDTG------KLSPETQSAIEQEIRILLRDSYERAKHILK 737

Query: 539  QHEKEWNAIATYLLKYETLKHEDIELIIQGKKPKV 643
             H KE   +A  LL YETL  ++I+++++GKK +V
Sbjct: 738  THAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEV 772
>sp|Q925S8|YMEL1_RAT ATP-dependent metalloprotease YME1L1 (YME1-like protein 1)
            (ATP-dependent metalloprotease FtsH1) (Meg-4)
          Length = 715

 Score =  163 bits (413), Expect = 5e-40
 Identities = 91/215 (42%), Positives = 136/215 (63%), Gaps = 1/215 (0%)
 Frame = +2

Query: 2    VSMDHIWEAESKILMGSVRNKPSLVSENRN-TAFHESGHCIVGYFTPNHPGKIKQITILP 178
            V+M  +  ++ KILMG  R    + ++N+  TA+HESGH I+ Y+T +    I + TI+P
Sbjct: 507  VTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAM-PINKATIMP 565

Query: 179  RGNSGGHSSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRATK 358
            RG + GH SL+P+ D +N  + QLLA +D  MGGR AEEL+ G+D+I+TG   D   ATK
Sbjct: 566  RGPTLGHVSLLPENDRWNEIRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATK 625

Query: 359  YARSMVMSYSMSEDVGLQTISDGNCSCGGRPLSGKLADTIDIEVNKILKESYERAKSLIQ 538
             A+ MV  + MSE +G+ T SD         LS +    I+ E+  +L+ESYERAK +++
Sbjct: 626  IAKRMVTKFGMSEKLGVMTYSDTG------KLSPETQSAIEQEIRILLRESYERAKHILK 679

Query: 539  QHEKEWNAIATYLLKYETLKHEDIELIIQGKKPKV 643
             H KE   +A  LL YETL  ++I+++++GKK +V
Sbjct: 680  THAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEV 714
>sp|P46508|YME1_SCHMA YME1 protein homolog
          Length = 662

 Score =  142 bits (357), Expect = 1e-33
 Identities = 74/210 (35%), Positives = 123/210 (58%)
 Frame = +2

Query: 2    VSMDHIWEAESKILMGSVRNKPSLVSENRNTAFHESGHCIVGYFTPNHPGKIKQITILPR 181
            V M H+W+A  +++MG  + +P     NR +AFHE+GH +V   T +    + ++TI+PR
Sbjct: 392  VEMHHLWDARDRLIMGPAKRRPLDDQTNRVSAFHEAGHALVALLTADSI-PLHKVTIIPR 450

Query: 182  GNSGGHSSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRATKY 361
            G +GG +S + ++D   M++ QLLA +D LMGGR  EEL+ G+D ++ G  DD ++AT  
Sbjct: 451  GEAGGLTSFLQEKDISFMTRAQLLAQLDVLMGGRVGEELVFGADKVTNGAADDFRKATIL 510

Query: 362  ARSMVMSYSMSEDVGLQTISDGNCSCGGRPLSGKLADTIDIEVNKILKESYERAKSLIQQ 541
            A++MV  +  S  +G + I D         L     D ID EV+++L +S  R ++L+  
Sbjct: 511  AQNMVKRFGFSSKIGPRVIPDTQ----DEQLGEATRDLIDKEVDQLLNDSLTRVRTLLSS 566

Query: 542  HEKEWNAIATYLLKYETLKHEDIELIIQGK 631
              K+   +A  LL +ETL  +++  ++ GK
Sbjct: 567  QSKQHKLLAEALLHFETLTKDEVLAVLAGK 596
>sp|P94304|FTSH_BACPF Cell division protein ftsH homolog
          Length = 679

 Score =  139 bits (351), Expect = 7e-33
 Identities = 91/248 (36%), Positives = 140/248 (56%), Gaps = 14/248 (5%)
 Frame = +2

Query: 2    VSMDHIWEAESKILMGSVRNKPSLVS--ENRNTAFHESGHCIVGYFTPNHPGKIKQITIL 175
            +SM HI EA  +++ G  + K  ++S  E +  A+HE+GH +VG    N    + ++TI+
Sbjct: 394  ISMIHIEEAIDRVIAGPAK-KSRVISPKEKKIVAWHEAGHTVVGVKLEN-ADMVHKVTIV 451

Query: 176  PRGNSGGHSSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRAT 355
            PRG +GG++ ++PKED Y M++ +LL  I  L+GGR AEE+  G   +STG ++D QRAT
Sbjct: 452  PRGMAGGYAVMLPKEDRYFMTQPELLDKIIGLLGGRVAEEVTFG--EVSTGAHNDFQRAT 509

Query: 356  KYARSMVMSYSMSEDVGLQTISDGNCSCGGRPLSGK-----------LADTIDIEVNKIL 502
              AR MV  Y MSE +G      G+   GG+   G+           +A  ID+EV +I+
Sbjct: 510  GIARKMVTEYGMSEKLGPMQFISGS---GGQVFLGRDIQNEQNYSDAIAHEIDLEVQRII 566

Query: 503  KESYERAKSLIQQHEKEWNAIATYLLKYETLKHEDIE-LIIQGKKPKVAIIHEEIQKNKK 679
            KE Y R K ++ +++   + +A  LL  ETL  E I+ L+ +GK P    ++   +K K 
Sbjct: 567  KECYARCKQILLENKDSLDLVAKTLLDMETLDAEQIKSLVHEGKLPDDHHLNAHPEKEKA 626

Query: 680  SFVDATSN 703
            S  D   N
Sbjct: 627  SESDVKVN 634
>sp|P32795|YME1_YEAST YME1 protein (TAT-binding homolog 11) (OSD1 protein)
          Length = 747

 Score =  139 bits (350), Expect = 9e-33
 Identities = 85/212 (40%), Positives = 124/212 (58%), Gaps = 1/212 (0%)
 Frame = +2

Query: 2    VSMDHIWEAESKILMGSVRNKPSLVSENRN-TAFHESGHCIVGYFTPNHPGKIKQITILP 178
            V M H   A+ KILMG+ R    L    R  TAFHE+GH I+  +T N    + + TILP
Sbjct: 506  VDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYT-NGATPLYKATILP 564

Query: 179  RGNSGGHSSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRATK 358
            RG + G +  +P+ D  +++K +  A +D  MGG+ AEEL+ G DN ++G   DLQ AT 
Sbjct: 565  RGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATG 624

Query: 359  YARSMVMSYSMSEDVGLQTISDGNCSCGGRPLSGKLADTIDIEVNKILKESYERAKSLIQ 538
             AR+MV  Y MS+DVG   +S+          S K+ D  D EV ++LK+S ERA+ L+ 
Sbjct: 625  TARAMVTQYGMSDDVGPVNLSE-----NWESWSNKIRDIADNEVIELLKDSEERARRLLT 679

Query: 539  QHEKEWNAIATYLLKYETLKHEDIELIIQGKK 634
            +   E + +A  L++YETL   +IE + +G+K
Sbjct: 680  KKNVELHRLAQGLIEYETLDAHEIEQVCKGEK 711
>sp|Q98PE4|FTSH_MYCPU Cell division protein ftsH homolog
          Length = 725

 Score =  137 bits (345), Expect = 3e-32
 Identities = 90/238 (37%), Positives = 136/238 (57%), Gaps = 9/238 (3%)
 Frame = +2

Query: 23   EAESKILMGSVRNKPSLVSEN-RNTAFHESGHCIVGYFTPNHPGKIKQITILPRGNSGGH 199
            EA  +++ G  +    +  E  +  A+HE+GH +VG        K+++ITI+PRGN+GG+
Sbjct: 447  EAIDRVMAGPAKKSRVISQEELKAVAYHEAGHAVVGLKVKGG-NKVQKITIIPRGNAGGY 505

Query: 200  SSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRATKYARSMVM 379
            + + P+E+ YN SK +LLA I S MGGRAAE ++ G +NISTG  DD+ RATK AR MV 
Sbjct: 506  NLMTPEEEKYNASKKELLATIASYMGGRAAEMIIYGKENISTGASDDISRATKIARKMVT 565

Query: 380  SYSMSEDVGLQTISDGNCSCGGRPLS-----GKLADTIDIEVNKILKESYERAKSLIQQH 544
             + MS    ++   D      GR  S      K+A  ID+E+ KI+  S E A   I+Q+
Sbjct: 566  EWGMSALGPIKYEEDTENPFLGRDYSKGTFGSKMAHEIDLEIRKIISASEEIAIKAIEQN 625

Query: 545  EKEWNAIATYLLKYETLKHEDIELIIQGKKPKVAIIHEEIQ---KNKKSFVDATSNQL 709
             +    I   LL+ ET+  E+IE I   K  K+   +E+I+   ++KK  ++   NQ+
Sbjct: 626  LELLELIKDSLLENETIVAEEIEYI--EKNMKLPPNNEKIKPDGESKKVNIEDLINQV 681
>sp|P37476|FTSH_BACSU Cell division protein ftsH homolog
          Length = 637

 Score =  130 bits (327), Expect = 4e-30
 Identities = 81/216 (37%), Positives = 123/216 (56%), Gaps = 10/216 (4%)
 Frame = +2

Query: 23   EAESKILMGSVRNKPSLVSENRN-TAFHESGHCIVGYFTPNHPGKIKQITILPRGNSGGH 199
            EA  +++ G  +    +  + RN  A+HE GH ++G    +    + ++TI+PRG +GG+
Sbjct: 396  EATDRVIAGPAKKSRVISKKERNIVAYHEGGHTVIGLVL-DEADMVHKVTIVPRGQAGGY 454

Query: 200  SSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRATKYARSMVM 379
            + ++P+ED Y  +K +LL  I  L+GGR AEE++ G   +STG ++D QRAT  AR MV 
Sbjct: 455  AVMLpreDRYFQTKPELLDKIVGLLGGRVAEEIIFG--EVSTGAHNDFQRATNIARRMVT 512

Query: 380  SYSMSEDVGLQTI--SDGNCSCGGRPL------SGKLADTIDIEVNKILKESYERAKSLI 535
             + MSE +G      S G     GR        S ++A  ID E+ +I+KE YERAK ++
Sbjct: 513  EFGMSEKLGPLQFGQSQGGQVFLGRDFNNEQNYSDQIAYEIDQEIQRIIKECYERAKQIL 572

Query: 536  QQHEKEWNAIATYLLKYETLKHEDIE-LIIQGKKPK 640
             ++  +   IA  LLK ETL  E I+ LI  G  P+
Sbjct: 573  TENRDKLELIAQTLLKVETLDAEQIKHLIDHGTLPE 608
>sp|Q89AF2|FTSH_BUCBP Cell division protein ftsH
          Length = 610

 Score =  130 bits (327), Expect = 4e-30
 Identities = 76/218 (34%), Positives = 130/218 (59%), Gaps = 8/218 (3%)
 Frame = +2

Query: 2    VSMDHIWEAESKILMGSVRNKPSLVSENR-NTAFHESGHCIVGYFTPNHPGKIKQITILP 178
            V M     A+ KI MGS R    +  + + +TA+HE+GH IVG   P H    K +TI+P
Sbjct: 380  VMMSDFESAKDKITMGSERRSMVMTEKQKESTAYHEAGHVIVGRLVPEHDPAHK-VTIIP 438

Query: 179  RGNSGGHSSLIPKEDSYNMSKNQLLAVIDSLMGGRAAEELLNGSDNISTGIYDDLQRATK 358
            RG + G +  +PK+D  +++KN+L + I +L GGR AEE++ G +N+STG ++D++ AT 
Sbjct: 439  RGRALGVTFFLPKDDVLSINKNKLESQISTLYGGRLAEEIIYGVNNVSTGAHNDIKVATN 498

Query: 359  YARSMVMSYSMSEDVG--LQTISDGNCSCG-----GRPLSGKLADTIDIEVNKILKESYE 517
             AR+MV  +  S+ +G  L +  +G    G      + +S + A  ID EV  +++++Y 
Sbjct: 499  LARNMVTQWGFSKKLGPLLYSEEEGEIFLGRTVTKSKHMSDETARIIDEEVKLLVEKNYN 558

Query: 518  RAKSLIQQHEKEWNAIATYLLKYETLKHEDIELIIQGK 631
            RAK +++++    +A+   L+KYET+    I+ +++ K
Sbjct: 559  RAKKILEENLDILHAMKDALIKYETINSRQIDDLMKRK 596
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,016,011
Number of Sequences: 369166
Number of extensions: 1902829
Number of successful extensions: 5081
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4809
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4975
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)