Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02727
(306 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P48067|SC6A9_HUMAN Sodium- and chloride-dependent glycin... 143 1e-34
sp|P28572|SC6A9_RAT Sodium- and chloride-dependent glycine ... 142 2e-34
sp|Q28039|SC6A9_BOVIN Sodium- and chloride-dependent glycin... 142 2e-34
sp|P28571|SC6A9_MOUSE Sodium- and chloride-dependent glycin... 139 2e-33
sp|P58295|SC6A5_RAT Sodium- and chloride-dependent glycine ... 135 4e-32
sp|Q9Y345|SC6A5_HUMAN Sodium- and chloride-dependent glycin... 135 4e-32
sp|Q761V0|SC6A5_MOUSE Sodium- and chloride-dependent glycin... 135 4e-32
sp|Q9UN76|S6A14_HUMAN Sodium- and chloride-dependent neutra... 126 1e-29
sp|Q9JMA9|S6A14_MOUSE Sodium- and chloride-dependent neutra... 126 2e-29
sp|P28570|SC6A8_RAT Sodium- and chloride-dependent creatine... 125 4e-29
>sp|P48067|SC6A9_HUMAN Sodium- and chloride-dependent glycine transporter 1 (GlyT1)
(GlyT-1) (Solute carrier family 6 member 9)
Length = 692
Score = 143 bits (360), Expect = 1e-34
Identities = 65/101 (64%), Positives = 84/101 (83%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IF+SL+C GGLI MASY+KF NNC RD+V++++ NCATSV+AGFVIF+ LGFMAN V
Sbjct: 354 IFYSLACAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGV 413
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
+ +VA GPGLAF+ YPEAL+ +PI+PLWS+LFFFM++ L
Sbjct: 414 DVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILL 454
>sp|P28572|SC6A9_RAT Sodium- and chloride-dependent glycine transporter 1 (GlyT1)
(GlyT-1) (Solute carrier family 6 member 9)
Length = 633
Score = 142 bits (359), Expect = 2e-34
Identities = 65/101 (64%), Positives = 83/101 (82%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IF+SL C GGLI MASY+KF NNC RD+V++++ NCATSV+AGFVIF+ LGFMAN V
Sbjct: 295 IFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGV 354
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
+ +VA GPGLAF+ YPEAL+ +PI+PLWS+LFFFM++ L
Sbjct: 355 DVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILL 395
>sp|Q28039|SC6A9_BOVIN Sodium- and chloride-dependent glycine transporter 1 (GlyT1)
(GlyT-1) (Solute carrier family 6 member 9)
Length = 638
Score = 142 bits (358), Expect = 2e-34
Identities = 64/101 (63%), Positives = 83/101 (82%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IF+SL C GGL+ MASY+KF NNC RD+V++++ NCATSV+AGFVIF+ LGFMAN V
Sbjct: 300 IFYSLGCAWGGLVTMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGV 359
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
+ +VA GPGLAF+ YPEAL+ +PI+PLWS+LFFFM++ L
Sbjct: 360 DVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILL 400
>sp|P28571|SC6A9_MOUSE Sodium- and chloride-dependent glycine transporter 1 (GlyT1)
(GlyT-1) (Solute carrier family 6 member 9)
Length = 633
Score = 139 bits (351), Expect = 2e-33
Identities = 63/101 (62%), Positives = 82/101 (81%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IF+SL C GGLI MASY+KF NNC RD+V++++ NCAT ++AGFVIF+ LGFMAN V
Sbjct: 295 IFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATRLYAGFVIFSILGFMANHLGV 354
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
+ +VA GPGLAF+ YPEAL+ +PI+PLWS+LFFFM++ L
Sbjct: 355 DVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILL 395
>sp|P58295|SC6A5_RAT Sodium- and chloride-dependent glycine transporter 2 (GlyT2)
(GlyT-2) (Solute carrier family 6 member 5)
Length = 799
Score = 135 bits (339), Expect = 4e-32
Identities = 61/101 (60%), Positives = 80/101 (79%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IFFSLS GGLI ++SY+KF NNC RD ++V N ATS+FAGFVIF+ +GFMAN + V
Sbjct: 476 IFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKV 535
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
I+ VA GPG+AF+VYPEAL+ +P++P W+I+FF M+LTL
Sbjct: 536 NIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTL 576
>sp|Q9Y345|SC6A5_HUMAN Sodium- and chloride-dependent glycine transporter 2 (GlyT2)
(GlyT-2) (Solute carrier family 6 member 5)
Length = 797
Score = 135 bits (339), Expect = 4e-32
Identities = 61/101 (60%), Positives = 80/101 (79%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IFFSLS GGLI ++SY+KF NNC RD ++V N ATS+FAGFVIF+ +GFMAN + V
Sbjct: 474 IFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKV 533
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
I+ VA GPG+AF+VYPEAL+ +P++P W+I+FF M+LTL
Sbjct: 534 NIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTL 574
>sp|Q761V0|SC6A5_MOUSE Sodium- and chloride-dependent glycine transporter 2 (GlyT2)
(GlyT-2) (Solute carrier family 6 member 5)
Length = 799
Score = 135 bits (339), Expect = 4e-32
Identities = 61/101 (60%), Positives = 80/101 (79%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IFFSLS GGLI ++SY+KF NNC RD ++V N ATS+FAGFVIF+ +GFMAN + V
Sbjct: 476 IFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKV 535
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
I+ VA GPG+AF+VYPEAL+ +P++P W+I+FF M+LTL
Sbjct: 536 NIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTL 576
>sp|Q9UN76|S6A14_HUMAN Sodium- and chloride-dependent neutral and basic amino acid
transporter B(0+) (Amino acid transporter ATB0+) (Solute
carrier family 6 member 14)
Length = 642
Score = 126 bits (317), Expect = 1e-29
Identities = 60/101 (59%), Positives = 75/101 (74%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IF+SLS GGL+ ++SY+KFKNNC DA++V L NC TSVFAGF IF+ LG MA++
Sbjct: 319 IFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGK 378
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
+ +V K G LAFI YPEAL+ +P P WSILFFFM+LTL
Sbjct: 379 EVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTL 419
>sp|Q9JMA9|S6A14_MOUSE Sodium- and chloride-dependent neutral and basic amino acid
transporter B(0+) (Amino acid transporter ATB0+)
(Colonic system B0+ amino acid transporter CATB0+)
(Solute carrier family 6 member 14)
Length = 638
Score = 126 bits (316), Expect = 2e-29
Identities = 59/101 (58%), Positives = 74/101 (73%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IF+SLS GGL+ ++SY+KF NNC DA++V L NC TSVFAGF IF+ LG MA++
Sbjct: 315 IFYSLSVAWGGLVALSSYNKFNNNCYSDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGK 374
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
+ +V K G LAFI YPEAL+ +P P WSILFFFM+LTL
Sbjct: 375 EVSQVVKSGFDLAFIAYPEALAQLPAGPFWSILFFFMLLTL 415
>sp|P28570|SC6A8_RAT Sodium- and chloride-dependent creatine transporter 1 (CT1)
(Creatine transporter 1) (CHOT1) (Solute carrier family
6 member 8)
Length = 635
Score = 125 bits (313), Expect = 4e-29
Identities = 59/101 (58%), Positives = 76/101 (75%)
Frame = +2
Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181
IFFS + G L + SY++F NNC +DA+++ALIN TS FAGFV+F+ LGFMA + V
Sbjct: 313 IFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGV 372
Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304
I KVA+ GPGLAFI YP A++ MP+APLW+ LFFFM+L L
Sbjct: 373 HISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLL 413
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,522,546
Number of Sequences: 369166
Number of extensions: 681313
Number of successful extensions: 1971
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1916
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1960
length of database: 68,354,980
effective HSP length: 70
effective length of database: 55,423,530
effective search space used: 1718129430
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)