Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_024_G19 (306 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P48067|SC6A9_HUMAN Sodium- and chloride-dependent glycin... 143 1e-34 sp|P28572|SC6A9_RAT Sodium- and chloride-dependent glycine ... 142 2e-34 sp|Q28039|SC6A9_BOVIN Sodium- and chloride-dependent glycin... 142 2e-34 sp|P28571|SC6A9_MOUSE Sodium- and chloride-dependent glycin... 139 2e-33 sp|P58295|SC6A5_RAT Sodium- and chloride-dependent glycine ... 135 4e-32 sp|Q9Y345|SC6A5_HUMAN Sodium- and chloride-dependent glycin... 135 4e-32 sp|Q761V0|SC6A5_MOUSE Sodium- and chloride-dependent glycin... 135 4e-32 sp|Q9UN76|S6A14_HUMAN Sodium- and chloride-dependent neutra... 126 1e-29 sp|Q9JMA9|S6A14_MOUSE Sodium- and chloride-dependent neutra... 126 2e-29 sp|P28570|SC6A8_RAT Sodium- and chloride-dependent creatine... 125 4e-29
>sp|P48067|SC6A9_HUMAN Sodium- and chloride-dependent glycine transporter 1 (GlyT1) (GlyT-1) (Solute carrier family 6 member 9) Length = 692 Score = 143 bits (360), Expect = 1e-34 Identities = 65/101 (64%), Positives = 84/101 (83%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IF+SL+C GGLI MASY+KF NNC RD+V++++ NCATSV+AGFVIF+ LGFMAN V Sbjct: 354 IFYSLACAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGV 413 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 + +VA GPGLAF+ YPEAL+ +PI+PLWS+LFFFM++ L Sbjct: 414 DVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILL 454
>sp|P28572|SC6A9_RAT Sodium- and chloride-dependent glycine transporter 1 (GlyT1) (GlyT-1) (Solute carrier family 6 member 9) Length = 633 Score = 142 bits (359), Expect = 2e-34 Identities = 65/101 (64%), Positives = 83/101 (82%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IF+SL C GGLI MASY+KF NNC RD+V++++ NCATSV+AGFVIF+ LGFMAN V Sbjct: 295 IFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGV 354 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 + +VA GPGLAF+ YPEAL+ +PI+PLWS+LFFFM++ L Sbjct: 355 DVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILL 395
>sp|Q28039|SC6A9_BOVIN Sodium- and chloride-dependent glycine transporter 1 (GlyT1) (GlyT-1) (Solute carrier family 6 member 9) Length = 638 Score = 142 bits (358), Expect = 2e-34 Identities = 64/101 (63%), Positives = 83/101 (82%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IF+SL C GGL+ MASY+KF NNC RD+V++++ NCATSV+AGFVIF+ LGFMAN V Sbjct: 300 IFYSLGCAWGGLVTMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGV 359 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 + +VA GPGLAF+ YPEAL+ +PI+PLWS+LFFFM++ L Sbjct: 360 DVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILL 400
>sp|P28571|SC6A9_MOUSE Sodium- and chloride-dependent glycine transporter 1 (GlyT1) (GlyT-1) (Solute carrier family 6 member 9) Length = 633 Score = 139 bits (351), Expect = 2e-33 Identities = 63/101 (62%), Positives = 82/101 (81%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IF+SL C GGLI MASY+KF NNC RD+V++++ NCAT ++AGFVIF+ LGFMAN V Sbjct: 295 IFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATRLYAGFVIFSILGFMANHLGV 354 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 + +VA GPGLAF+ YPEAL+ +PI+PLWS+LFFFM++ L Sbjct: 355 DVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILL 395
>sp|P58295|SC6A5_RAT Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5) Length = 799 Score = 135 bits (339), Expect = 4e-32 Identities = 61/101 (60%), Positives = 80/101 (79%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IFFSLS GGLI ++SY+KF NNC RD ++V N ATS+FAGFVIF+ +GFMAN + V Sbjct: 476 IFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKV 535 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 I+ VA GPG+AF+VYPEAL+ +P++P W+I+FF M+LTL Sbjct: 536 NIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTL 576
>sp|Q9Y345|SC6A5_HUMAN Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5) Length = 797 Score = 135 bits (339), Expect = 4e-32 Identities = 61/101 (60%), Positives = 80/101 (79%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IFFSLS GGLI ++SY+KF NNC RD ++V N ATS+FAGFVIF+ +GFMAN + V Sbjct: 474 IFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKV 533 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 I+ VA GPG+AF+VYPEAL+ +P++P W+I+FF M+LTL Sbjct: 534 NIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTL 574
>sp|Q761V0|SC6A5_MOUSE Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5) Length = 799 Score = 135 bits (339), Expect = 4e-32 Identities = 61/101 (60%), Positives = 80/101 (79%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IFFSLS GGLI ++SY+KF NNC RD ++V N ATS+FAGFVIF+ +GFMAN + V Sbjct: 476 IFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKV 535 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 I+ VA GPG+AF+VYPEAL+ +P++P W+I+FF M+LTL Sbjct: 536 NIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTL 576
>sp|Q9UN76|S6A14_HUMAN Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14) Length = 642 Score = 126 bits (317), Expect = 1e-29 Identities = 60/101 (59%), Positives = 75/101 (74%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IF+SLS GGL+ ++SY+KFKNNC DA++V L NC TSVFAGF IF+ LG MA++ Sbjct: 319 IFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGK 378 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 + +V K G LAFI YPEAL+ +P P WSILFFFM+LTL Sbjct: 379 EVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTL 419
>sp|Q9JMA9|S6A14_MOUSE Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Colonic system B0+ amino acid transporter CATB0+) (Solute carrier family 6 member 14) Length = 638 Score = 126 bits (316), Expect = 2e-29 Identities = 59/101 (58%), Positives = 74/101 (73%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IF+SLS GGL+ ++SY+KF NNC DA++V L NC TSVFAGF IF+ LG MA++ Sbjct: 315 IFYSLSVAWGGLVALSSYNKFNNNCYSDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGK 374 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 + +V K G LAFI YPEAL+ +P P WSILFFFM+LTL Sbjct: 375 EVSQVVKSGFDLAFIAYPEALAQLPAGPFWSILFFFMLLTL 415
>sp|P28570|SC6A8_RAT Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (CHOT1) (Solute carrier family 6 member 8) Length = 635 Score = 125 bits (313), Expect = 4e-29 Identities = 59/101 (58%), Positives = 76/101 (75%) Frame = +2 Query: 2 IFFSLSCCSGGLINMASYHKFKNNCCRDAVLVALINCATSVFAGFVIFANLGFMANVKNV 181 IFFS + G L + SY++F NNC +DA+++ALIN TS FAGFV+F+ LGFMA + V Sbjct: 313 IFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGV 372 Query: 182 TIDKVAKGGPGLAFIVYPEALSNMPIAPLWSILFFFMMLTL 304 I KVA+ GPGLAFI YP A++ MP+APLW+ LFFFM+L L Sbjct: 373 HISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLL 413
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,522,546 Number of Sequences: 369166 Number of extensions: 681313 Number of successful extensions: 1971 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1916 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1960 length of database: 68,354,980 effective HSP length: 70 effective length of database: 55,423,530 effective search space used: 1718129430 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)