Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02693 (847 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A 247 3e-65 sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A 244 2e-64 sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A 241 2e-63 sp|P05714|RAB4A_RAT Ras-related protein Rab-4A 239 7e-63 sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B 233 4e-61 sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B >gi|465776... 233 7e-61 sp|P51146|RAB4B_RAT Ras-related protein Rab-4B >gi|46577105... 232 9e-61 sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14 211 2e-54 sp|P61107|RAB14_RAT Ras-related protein Rab-14 >gi|46577643... 211 2e-54 sp|P36410|RAB4_DICDI Ras-related protein Rab4 202 7e-52
>sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A Length = 213 Score = 247 bits (631), Expect = 3e-65 Identities = 128/207 (61%), Positives = 164/207 (79%), Gaps = 4/207 (1%) Frame = +2 Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295 M++ YD+LFKFL+IGN+G GKSC+L+QFIE++F+ DS+HTIGVEF SKIIS+ N+ VKLQ Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDDSNHTIGVEFGSKIISVVNKFVKLQ 60 Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475 IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ L NWL D R L+ + I+IIL G Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCG 120 Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655 NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AFV AR+IL+ +E S Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIE---SG 176 Query: 656 GLD----NSADEFRSADVRRPYLRSPR 724 LD S ++ A +R+ LRSPR Sbjct: 177 ELDPERMGSGIQYGDAALRQ--LRSPR 201
>sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A Length = 213 Score = 244 bits (623), Expect = 2e-64 Identities = 126/207 (60%), Positives = 163/207 (78%), Gaps = 4/207 (1%) Frame = +2 Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295 M++ YD+LFKFL+IGN+G GKSC+L+QFIE++F+ DS+HTIGVEF SKII++ + VKLQ Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQ 60 Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475 IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ L NWL D R L+ + I+IIL G Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCG 120 Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655 NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AFV AR+IL+ +E S Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIE---SG 176 Query: 656 GLD----NSADEFRSADVRRPYLRSPR 724 LD S ++ A +R+ LRSPR Sbjct: 177 ELDPERMGSGIQYGDAALRQ--LRSPR 201
>sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A Length = 213 Score = 241 bits (615), Expect = 2e-63 Identities = 123/207 (59%), Positives = 163/207 (78%), Gaps = 4/207 (1%) Frame = +2 Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295 M++ YD+LFKFL+IGN+G GKSC+L+QFIE++F+ DS+HTIG+EF SKII++ + VKLQ Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGMEFGSKIINVGGKYVKLQ 60 Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475 IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ L NWL D R L+ + I++IL G Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVLILCG 120 Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655 NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR+IL+ +E S Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIE---SG 176 Query: 656 GLD----NSADEFRSADVRRPYLRSPR 724 LD S ++ A +R+ LRSPR Sbjct: 177 ELDPERMGSGIQYGDAALRQ--LRSPR 201
>sp|P05714|RAB4A_RAT Ras-related protein Rab-4A Length = 213 Score = 239 bits (610), Expect = 7e-63 Identities = 123/207 (59%), Positives = 161/207 (77%), Gaps = 4/207 (1%) Frame = +2 Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295 M++ YD+LFKFL+IGN+G GKSC+L+QFIE++F+ DS+HTIGVEF KII++ + VKLQ Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGQKIINVGGKYVKLQ 60 Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475 IWDTAGQERFRSVT SYYR AAGALLVYD+T R+++ L NWL D R L+ + I+IIL G Sbjct: 61 IWDTAGQERFRSVTTSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCG 120 Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655 NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR+IL+ +E S Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIE---SG 176 Query: 656 GLD----NSADEFRSADVRRPYLRSPR 724 LD S ++ A +R+ LRSPR Sbjct: 177 ELDPERMGSGIQYGDAALRQ--LRSPR 201
>sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B Length = 213 Score = 233 bits (595), Expect = 4e-61 Identities = 119/209 (56%), Positives = 159/209 (76%), Gaps = 4/209 (1%) Frame = +2 Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295 M++ YD+LFKFL+IG++G GKSC+L+QFIE +F+ DS+HTIGVEF S+++++ + VKLQ Sbjct: 1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60 Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475 IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ L NWL D R L+ I+IIL G Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCG 120 Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655 NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR I + +E S Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSIPNKIE---SG 176 Query: 656 GLD----NSADEFRSADVRRPYLRSPRDS 730 LD S ++ A +R+ +R PR S Sbjct: 177 ELDPERMGSGIQYGDASLRQ--IRQPRGS 203
>sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B sp|P61017|RAB4B_CANFA Ras-related protein Rab-4B Length = 213 Score = 233 bits (593), Expect = 7e-61 Identities = 118/209 (56%), Positives = 159/209 (76%), Gaps = 4/209 (1%) Frame = +2 Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295 M + YD+LFKFL+IG++G GKSC+L+QFIE +F+ DS+HTIGVEF S+++++ + VKLQ Sbjct: 1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60 Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475 IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ +L WL D R L+ I++IL G Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCG 120 Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655 NK D + ER+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR IL+ ++ S Sbjct: 121 NKKD-LDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKID---SG 176 Query: 656 GLD----NSADEFRSADVRRPYLRSPRDS 730 LD S ++ A +R+ LR PR + Sbjct: 177 ELDPERMGSGIQYGDASLRQ--LRQPRSA 203
>sp|P51146|RAB4B_RAT Ras-related protein Rab-4B sp|Q91ZR1|RAB4B_MOUSE Ras-related protein Rab-4B Length = 213 Score = 232 bits (592), Expect = 9e-61 Identities = 116/207 (56%), Positives = 155/207 (74%), Gaps = 2/207 (0%) Frame = +2 Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295 M + YD+LFKFL+IG++G GKSC+L+QFIE +F+ DS+HTIGVEF S+++++ + VKLQ Sbjct: 1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60 Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475 IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ +L WL D R L+ I++IL G Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCG 120 Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655 NK D + ER+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR IL+ ++ S Sbjct: 121 NKKD-LDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKID---SG 176 Query: 656 GLD--NSADEFRSADVRRPYLRSPRDS 730 LD + D+ LR PR + Sbjct: 177 ELDPERMGSGIQYGDISLRQLRQPRSA 203
>sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14 Length = 215 Score = 211 bits (538), Expect = 2e-54 Identities = 101/184 (54%), Positives = 140/184 (76%) Frame = +2 Query: 128 YDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQIWDT 307 Y Y+FK+++IG+ GVGKSC+L+QF E++F +D HTIGVEF ++II ++ +K+KLQIWDT Sbjct: 8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDT 67 Query: 308 AGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVGNKID 487 AGQERFR+VTRSYYR AAGAL+VYD+T R ++ +L++WL D R L+ +IIL+GNK D Sbjct: 68 AGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKAD 127 Query: 488 KSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSSGLDN 667 E +R V++ E QFA+EN L+F+E SA TGENV DAF+ A++I N++ LD Sbjct: 128 -LEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ---DGSLDL 183 Query: 668 SADE 679 +A E Sbjct: 184 NAAE 187
>sp|P61107|RAB14_RAT Ras-related protein Rab-14 sp|P61106|RAB14_HUMAN Ras-related protein Rab-14 Length = 215 Score = 211 bits (538), Expect = 2e-54 Identities = 101/184 (54%), Positives = 140/184 (76%) Frame = +2 Query: 128 YDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQIWDT 307 Y Y+FK+++IG+ GVGKSC+L+QF E++F +D HTIGVEF ++II ++ +K+KLQIWDT Sbjct: 8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDT 67 Query: 308 AGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVGNKID 487 AGQERFR+VTRSYYR AAGAL+VYD+T R ++ +L++WL D R L+ +IIL+GNK D Sbjct: 68 AGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKAD 127 Query: 488 KSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSSGLDN 667 E +R V++ E QFA+EN L+F+E SA TGENV DAF+ A++I N++ LD Sbjct: 128 -LEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ---DGSLDL 183 Query: 668 SADE 679 +A E Sbjct: 184 NAAE 187
>sp|P36410|RAB4_DICDI Ras-related protein Rab4 Length = 205 Score = 202 bits (515), Expect = 7e-52 Identities = 95/171 (55%), Positives = 133/171 (77%) Frame = +2 Query: 128 YDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQIWDT 307 Y+Y+FK+++IG+ GVGKSC+L+QF E +F DS HTIGVEF ++I+ + N+K+KLQIWDT Sbjct: 5 YEYIFKYIIIGDMGVGKSCLLHQFTENKFVPDSPHTIGVEFGTRIVDVNNKKIKLQIWDT 64 Query: 308 AGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVGNKID 487 AGQERFR+VTRSYYR AAGALLVYD+T R ++ +L WL D R L+ +I+L+GNK D Sbjct: 65 AGQERFRAVTRSYYRGAAGALLVYDITRRITYNHLTTWLTDARNLTNPNTVIMLIGNKKD 124 Query: 488 KSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVE 640 E +R V++ E + FA++N L+F+E+SA TGENV +AF+ A+ I +V+ Sbjct: 125 -LEGQRDVTYEEASAFAKQNGLIFVESSAKTGENVEEAFLRTAKLIFQSVQ 174
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 80,103,092 Number of Sequences: 369166 Number of extensions: 1465536 Number of successful extensions: 5148 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4538 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4666 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8293644780 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)