Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_A10
(847 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A 247 3e-65
sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A 244 2e-64
sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A 241 2e-63
sp|P05714|RAB4A_RAT Ras-related protein Rab-4A 239 7e-63
sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B 233 4e-61
sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B >gi|465776... 233 7e-61
sp|P51146|RAB4B_RAT Ras-related protein Rab-4B >gi|46577105... 232 9e-61
sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14 211 2e-54
sp|P61107|RAB14_RAT Ras-related protein Rab-14 >gi|46577643... 211 2e-54
sp|P36410|RAB4_DICDI Ras-related protein Rab4 202 7e-52
>sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A
Length = 213
Score = 247 bits (631), Expect = 3e-65
Identities = 128/207 (61%), Positives = 164/207 (79%), Gaps = 4/207 (1%)
Frame = +2
Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295
M++ YD+LFKFL+IGN+G GKSC+L+QFIE++F+ DS+HTIGVEF SKIIS+ N+ VKLQ
Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDDSNHTIGVEFGSKIISVVNKFVKLQ 60
Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475
IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ L NWL D R L+ + I+IIL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCG 120
Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655
NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AFV AR+IL+ +E S
Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIE---SG 176
Query: 656 GLD----NSADEFRSADVRRPYLRSPR 724
LD S ++ A +R+ LRSPR
Sbjct: 177 ELDPERMGSGIQYGDAALRQ--LRSPR 201
>sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A
Length = 213
Score = 244 bits (623), Expect = 2e-64
Identities = 126/207 (60%), Positives = 163/207 (78%), Gaps = 4/207 (1%)
Frame = +2
Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295
M++ YD+LFKFL+IGN+G GKSC+L+QFIE++F+ DS+HTIGVEF SKII++ + VKLQ
Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQ 60
Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475
IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ L NWL D R L+ + I+IIL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCG 120
Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655
NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AFV AR+IL+ +E S
Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIE---SG 176
Query: 656 GLD----NSADEFRSADVRRPYLRSPR 724
LD S ++ A +R+ LRSPR
Sbjct: 177 ELDPERMGSGIQYGDAALRQ--LRSPR 201
>sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A
Length = 213
Score = 241 bits (615), Expect = 2e-63
Identities = 123/207 (59%), Positives = 163/207 (78%), Gaps = 4/207 (1%)
Frame = +2
Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295
M++ YD+LFKFL+IGN+G GKSC+L+QFIE++F+ DS+HTIG+EF SKII++ + VKLQ
Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGMEFGSKIINVGGKYVKLQ 60
Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475
IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ L NWL D R L+ + I++IL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVLILCG 120
Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655
NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR+IL+ +E S
Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIE---SG 176
Query: 656 GLD----NSADEFRSADVRRPYLRSPR 724
LD S ++ A +R+ LRSPR
Sbjct: 177 ELDPERMGSGIQYGDAALRQ--LRSPR 201
>sp|P05714|RAB4A_RAT Ras-related protein Rab-4A
Length = 213
Score = 239 bits (610), Expect = 7e-63
Identities = 123/207 (59%), Positives = 161/207 (77%), Gaps = 4/207 (1%)
Frame = +2
Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295
M++ YD+LFKFL+IGN+G GKSC+L+QFIE++F+ DS+HTIGVEF KII++ + VKLQ
Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGQKIINVGGKYVKLQ 60
Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475
IWDTAGQERFRSVT SYYR AAGALLVYD+T R+++ L NWL D R L+ + I+IIL G
Sbjct: 61 IWDTAGQERFRSVTTSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCG 120
Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655
NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR+IL+ +E S
Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIE---SG 176
Query: 656 GLD----NSADEFRSADVRRPYLRSPR 724
LD S ++ A +R+ LRSPR
Sbjct: 177 ELDPERMGSGIQYGDAALRQ--LRSPR 201
>sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B
Length = 213
Score = 233 bits (595), Expect = 4e-61
Identities = 119/209 (56%), Positives = 159/209 (76%), Gaps = 4/209 (1%)
Frame = +2
Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295
M++ YD+LFKFL+IG++G GKSC+L+QFIE +F+ DS+HTIGVEF S+++++ + VKLQ
Sbjct: 1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60
Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475
IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ L NWL D R L+ I+IIL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCG 120
Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655
NK D + +R+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR I + +E S
Sbjct: 121 NKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSIPNKIE---SG 176
Query: 656 GLD----NSADEFRSADVRRPYLRSPRDS 730
LD S ++ A +R+ +R PR S
Sbjct: 177 ELDPERMGSGIQYGDASLRQ--IRQPRGS 203
>sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B
sp|P61017|RAB4B_CANFA Ras-related protein Rab-4B
Length = 213
Score = 233 bits (593), Expect = 7e-61
Identities = 118/209 (56%), Positives = 159/209 (76%), Gaps = 4/209 (1%)
Frame = +2
Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295
M + YD+LFKFL+IG++G GKSC+L+QFIE +F+ DS+HTIGVEF S+++++ + VKLQ
Sbjct: 1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60
Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475
IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ +L WL D R L+ I++IL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCG 120
Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655
NK D + ER+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR IL+ ++ S
Sbjct: 121 NKKD-LDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKID---SG 176
Query: 656 GLD----NSADEFRSADVRRPYLRSPRDS 730
LD S ++ A +R+ LR PR +
Sbjct: 177 ELDPERMGSGIQYGDASLRQ--LRQPRSA 203
>sp|P51146|RAB4B_RAT Ras-related protein Rab-4B
sp|Q91ZR1|RAB4B_MOUSE Ras-related protein Rab-4B
Length = 213
Score = 232 bits (592), Expect = 9e-61
Identities = 116/207 (56%), Positives = 155/207 (74%), Gaps = 2/207 (0%)
Frame = +2
Query: 116 MTDIYDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQ 295
M + YD+LFKFL+IG++G GKSC+L+QFIE +F+ DS+HTIGVEF S+++++ + VKLQ
Sbjct: 1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60
Query: 296 IWDTAGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVG 475
IWDTAGQERFRSVTRSYYR AAGALLVYD+T R+++ +L WL D R L+ I++IL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCG 120
Query: 476 NKIDKSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSS 655
NK D + ER+V+F+E ++FAQENELMF+ETSALTGENV +AF+ AR IL+ ++ S
Sbjct: 121 NKKD-LDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKID---SG 176
Query: 656 GLD--NSADEFRSADVRRPYLRSPRDS 730
LD + D+ LR PR +
Sbjct: 177 ELDPERMGSGIQYGDISLRQLRQPRSA 203
>sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14
Length = 215
Score = 211 bits (538), Expect = 2e-54
Identities = 101/184 (54%), Positives = 140/184 (76%)
Frame = +2
Query: 128 YDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQIWDT 307
Y Y+FK+++IG+ GVGKSC+L+QF E++F +D HTIGVEF ++II ++ +K+KLQIWDT
Sbjct: 8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDT 67
Query: 308 AGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVGNKID 487
AGQERFR+VTRSYYR AAGAL+VYD+T R ++ +L++WL D R L+ +IIL+GNK D
Sbjct: 68 AGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKAD 127
Query: 488 KSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSSGLDN 667
E +R V++ E QFA+EN L+F+E SA TGENV DAF+ A++I N++ LD
Sbjct: 128 -LEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ---DGSLDL 183
Query: 668 SADE 679
+A E
Sbjct: 184 NAAE 187
>sp|P61107|RAB14_RAT Ras-related protein Rab-14
sp|P61106|RAB14_HUMAN Ras-related protein Rab-14
Length = 215
Score = 211 bits (538), Expect = 2e-54
Identities = 101/184 (54%), Positives = 140/184 (76%)
Frame = +2
Query: 128 YDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQIWDT 307
Y Y+FK+++IG+ GVGKSC+L+QF E++F +D HTIGVEF ++II ++ +K+KLQIWDT
Sbjct: 8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDT 67
Query: 308 AGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVGNKID 487
AGQERFR+VTRSYYR AAGAL+VYD+T R ++ +L++WL D R L+ +IIL+GNK D
Sbjct: 68 AGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKAD 127
Query: 488 KSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVETVFSSGLDN 667
E +R V++ E QFA+EN L+F+E SA TGENV DAF+ A++I N++ LD
Sbjct: 128 -LEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ---DGSLDL 183
Query: 668 SADE 679
+A E
Sbjct: 184 NAAE 187
>sp|P36410|RAB4_DICDI Ras-related protein Rab4
Length = 205
Score = 202 bits (515), Expect = 7e-52
Identities = 95/171 (55%), Positives = 133/171 (77%)
Frame = +2
Query: 128 YDYLFKFLLIGNSGVGKSCVLNQFIEEQFRSDSSHTIGVEFASKIISIANRKVKLQIWDT 307
Y+Y+FK+++IG+ GVGKSC+L+QF E +F DS HTIGVEF ++I+ + N+K+KLQIWDT
Sbjct: 5 YEYIFKYIIIGDMGVGKSCLLHQFTENKFVPDSPHTIGVEFGTRIVDVNNKKIKLQIWDT 64
Query: 308 AGQERFRSVTRSYYRKAAGALLVYDVTDRDSFTNLNNWLIDIRQLSGEGIIIILVGNKID 487
AGQERFR+VTRSYYR AAGALLVYD+T R ++ +L WL D R L+ +I+L+GNK D
Sbjct: 65 AGQERFRAVTRSYYRGAAGALLVYDITRRITYNHLTTWLTDARNLTNPNTVIMLIGNKKD 124
Query: 488 KSEEERQVSFIEGTQFAQENELMFIETSALTGENVSDAFVNVARRILHNVE 640
E +R V++ E + FA++N L+F+E+SA TGENV +AF+ A+ I +V+
Sbjct: 125 -LEGQRDVTYEEASAFAKQNGLIFVESSAKTGENVEEAFLRTAKLIFQSVQ 174
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,103,092
Number of Sequences: 369166
Number of extensions: 1465536
Number of successful extensions: 5148
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4538
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4666
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)