Planaria EST Database


DrC_02669

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02669
         (821 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9Y2G4|ANKR6_HUMAN  Ankyrin repeat domain protein 6            127   3e-29
sp|P16157|ANK1_HUMAN  Ankyrin-1 (Erythrocyte ankyrin) (Ankyr...    96   9e-20
sp|Q12955|ANK3_HUMAN  Ankyrin-3 (ANK-3) (Ankyrin G)                96   1e-19
sp|Q92625|ANKS1_HUMAN  Ankyrin repeat and SAM domain-contain...    96   2e-19
sp|Q02357|ANK1_MOUSE  Ankyrin-1 (Erythrocyte ankyrin)              95   2e-19
sp|Q9WV06|ANR2_MOUSE  Ankyrin repeat domain protein 2 (Skele...    95   3e-19
sp|Q59H18|TNI3K_HUMAN  Serine/threonine-protein kinase TNNI3...    93   1e-18
sp|P57078|RIPK4_HUMAN  Serine/threonine-protein kinase RIPK4...    92   2e-18
sp|Q5RF15|TNI3K_PONPY  Serine/threonine-protein kinase TNNI3...    91   3e-18
sp|Q80YE7|DAPK1_MOUSE  Death-associated protein kinase 1 (DA...    90   7e-18
>sp|Q9Y2G4|ANKR6_HUMAN Ankyrin repeat domain protein 6
          Length = 692

 Score =  127 bits (320), Expect = 3e-29
 Identities = 63/152 (41%), Positives = 96/152 (63%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           GNT LHEA+W G+SQ+ + L + G      N +  T LHLA Q  H+Q+TR L+  G+  
Sbjct: 108 GNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRA 167

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           + +N  GDT LH   RY H  + R+L++    ++++NQ GDT+LH+AAAL  +K+ K+L+
Sbjct: 168 DLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILL 227

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           E+GA+  I N   +TPL+ A   N+ E+  +L
Sbjct: 228 EAGADTTIVNNAGQTPLETARYHNNPEVALLL 259

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 51/163 (31%), Positives = 92/163 (56%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           HG TPLH AA KG+   V+ L + G   ++ +    T LH A   G+ +    LI  G  
Sbjct: 41  HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA 100

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
           ++ Q++ G+T LH    +G +  +++L+   +++  +N+ G+T+LH+A      + T++L
Sbjct: 101 LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL 160

Query: 376 VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQK 504
           + +G+  D++N   +T L VA + NH  II +L  + CS ++K
Sbjct: 161 LLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEK 203

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 34/115 (29%), Positives = 51/115 (44%)
 Frame = +1

Query: 130 LHLAVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQN 309
           L +A   G  +    LI  GA + A  + G TPLH     GH  V +IL+    D++ Q+
Sbjct: 14  LLVAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQD 72

Query: 310 QNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
               T+LH A  +   +I   L+  G  LD ++    T L  A     S+   +L
Sbjct: 73  DGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLL 127

 Score = 34.3 bits (77), Expect = 0.42
 Identities = 18/65 (27%), Positives = 39/65 (60%)
 Frame = +1

Query: 310 QNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSIC 489
           ++G T LH+AA      + ++L+++G +LD+++  ++T L  A    ++EII  L    C
Sbjct: 40  KHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGC 99

Query: 490 SSNQK 504
           + +++
Sbjct: 100 ALDRQ 104
>sp|P16157|ANK1_HUMAN Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin R)
          Length = 1881

 Score = 96.3 bits (238), Expect = 9e-20
 Identities = 55/177 (31%), Positives = 91/177 (51%), Gaps = 1/177 (0%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           +G TPLH A  K + + +E L + G   + V  S  TPLH+A   GH    +NL++ GA 
Sbjct: 370 NGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 429

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
            N  N   +TPLH   R GH  V++ L+   + +N + ++  T LH AA +    + KLL
Sbjct: 430 PNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489

Query: 376 VESGANLDIRNIQNETPLDVAIKKNHSE-IIDILKMSICSSNQKTVSFLPENIRENF 543
           +E+ AN ++      TPL +A ++ H E ++ +L+     +      F P ++   +
Sbjct: 490 LENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKY 546

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 63/187 (33%), Positives = 96/187 (51%), Gaps = 6/187 (3%)
 Frame = +1

Query: 7    DSTHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKC 186
            +S  G TPLH AA +G+++ V  L       NL N S  TPLHL  Q GH      LIK 
Sbjct: 631  ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH 690

Query: 187  GADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKIT 366
            G  ++A  R G TPLH    YG+  + + L+   +D+N + + G + LH AA      I 
Sbjct: 691  GVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIV 750

Query: 367  KLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKM------SICSSNQKTVSFLPEN 528
             LL+++GA+ +  +    TPL +A +  +  + D+LK+       +  S++  +SF PE 
Sbjct: 751  TLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRMSF-PET 809

Query: 529  IRENFSV 549
            + E   V
Sbjct: 810  VDEILDV 816

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 51/152 (33%), Positives = 80/152 (52%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           G TPLH A++ G+   V+ L Q G  PN+ N  + TPLH+A + GH +  + L++  A +
Sbjct: 404 GLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKV 463

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           NA+ +   TPLH   R GH  + ++L+  +++ N     G T LHIAA     +    L+
Sbjct: 464 NAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALL 523

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           E  A+      +  TPL VA K     + ++L
Sbjct: 524 EKEASQACMTKKGFTPLHVAAKYGKVRVAELL 555

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 49/163 (30%), Positives = 84/163 (51%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           +G +P+H AA   +   V  L Q     + +     TPLH+A   GH++  + L+  GA 
Sbjct: 304 NGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK 363

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
            N++   G TPLH   +  H  V  +L+   + I+   ++G T LH+A+ +    I K L
Sbjct: 364 PNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNL 423

Query: 376 VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQK 504
           ++ GA+ ++ N++ ETPL +A +  H+E+   L  +    N K
Sbjct: 424 LQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAK 466

 Score = 87.0 bits (214), Expect = 6e-17
 Identities = 50/163 (30%), Positives = 83/163 (50%)
 Frame = +1

Query: 25  TPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
           TPLH AA  G+ +  + L   G  PN    + FTPLH+A +  H +    L+K GA I+A
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399

Query: 205 QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
               G TPLH     GH  + + L+   +  N  N   +T LH+AA     ++ K L+++
Sbjct: 400 VTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 459

Query: 385 GANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVS 513
            A ++ +   ++TPL  A +  H+ ++ +L  +  + N  T +
Sbjct: 460 KAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTA 502

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 52/168 (30%), Positives = 85/168 (50%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           +G TPLH A+ +G    V  L   G           TPLH A + GH + +  L+  GA 
Sbjct: 238 NGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAP 297

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
           I A+ + G +P+H   +  H    R+L+   ++I+    +  T LH+AA     ++ K+L
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 357

Query: 376 VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVSFL 519
           ++ GA  + R +   TPL +A KKNH  ++++L  +  S +  T S L
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL 405

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 54/162 (33%), Positives = 80/162 (49%)
 Frame = +1

Query: 25  TPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
           TPLH AA  G++  V+ L +    PNL   +  TPLH+A + GH +T   L++  A    
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531

Query: 205 QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
             + G TPLH   +YG   V+ +L+   +  N   +NG T LH+A       I KLL+  
Sbjct: 532 MTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPR 591

Query: 385 GANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTV 510
           G +         TPL +A K+N  E+   L     S+N ++V
Sbjct: 592 GGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESV 633

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 49/163 (30%), Positives = 87/163 (53%)
 Frame = +1

Query: 10  STHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCG 189
           +T G+TPLH AA +G+ +TV  L +       +    FTPLH+A + G  +    L++  
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559

Query: 190 ADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITK 369
           A  NA  + G TPLH  V + +  + ++L+      +    NG T LHIAA   + ++ +
Sbjct: 560 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVAR 619

Query: 370 LLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSN 498
            L++ G + +  ++Q  TPL +A ++ H+E++ +L     + N
Sbjct: 620 SLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGN 662

 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 51/162 (31%), Positives = 83/162 (51%)
 Frame = +1

Query: 16   HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
            +G TPLH AA +   +    L Q G   N  +    TPLHLA Q GH +    L+   A+
Sbjct: 601  NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660

Query: 196  INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
             N  N+ G TPLH   + GH  V+ +LI     ++   + G T LH+A+     K+ K L
Sbjct: 661  GNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 720

Query: 376  VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQ 501
            ++  A+++ +     +PL  A ++ H++I+ +L  +  S N+
Sbjct: 721  LQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNE 762

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 56/203 (27%), Positives = 98/203 (48%), Gaps = 7/203 (3%)
 Frame = +1

Query: 16   HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
            +G TPLH A        V+ L   G  P+   ++ +TPLH+A +    +  R+L++ G  
Sbjct: 568  NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 627

Query: 196  INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
             NA++  G TPLH   + GHA +  +L+S  ++ N  N++G T LH+ A      +  +L
Sbjct: 628  ANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVL 687

Query: 376  VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKT-VSFLP------ENIR 534
            ++ G  +D       TPL VA    + +++  L       N KT + + P      +   
Sbjct: 688  IKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHT 747

Query: 535  ENFSVQSRHVSIPNEMCSVVNTP 603
            +  ++  ++ + PNE+ S   TP
Sbjct: 748  DIVTLLLKNGASPNEVSSDGTTP 770

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 54/184 (29%), Positives = 85/184 (46%), Gaps = 29/184 (15%)
 Frame = +1

Query: 10  STHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCG 189
           S  G TPL+ AA + + + V++L + G   N+     FTPL +A+Q GH     +LI  G
Sbjct: 108 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 167

Query: 190 A---------DINAQN--------------------RFGDTPLHTGVRYGHAGVSRILIS 282
                      I A+N                    + G TPLH    Y +  V+++L++
Sbjct: 168 TKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN 227

Query: 283 VSSDINQQNQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEI 462
             + +N   QNG T LHIA+      + +LL++ GA ++ +     TPL  A +  H  I
Sbjct: 228 RGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRI 287

Query: 463 IDIL 474
            +IL
Sbjct: 288 SEIL 291

 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 46/152 (30%), Positives = 71/152 (46%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           G TPLH AA  G  +  E L +    PN    +  TPLH+AV   +    + L+  G   
Sbjct: 536 GFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP 595

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           ++    G TPLH   +     V+R L+      N ++  G T LH+AA     ++  LL+
Sbjct: 596 HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 655

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
              AN ++ N    TPL +  ++ H  + D+L
Sbjct: 656 SKQANGNLGNKSGLTPLHLVAQEGHVPVADVL 687

 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 52/184 (28%), Positives = 89/184 (48%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           GNT LH AA  G  + V  L   G   N  +   FTPL++A Q  H +  + L++ GA+ 
Sbjct: 78  GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQ 137

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           N     G TPL   ++ GH  V   LI+  +    + +    +LHIAA     +   +L+
Sbjct: 138 NVATEDGFTPLAVALQQGHENVVAHLINYGT----KGKVRLPALHIAARNDDTRTAAVLL 193

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVSFLPENIRENFSVQSR 558
           ++  N D+ +    TPL +A    H E +++ ++ +  +   +V+F P+N      + SR
Sbjct: 194 QNDPNPDVLSKTGFTPLHIAA---HYENLNVAQLLL--NRGASVNFTPQNGITPLHIASR 248

Query: 559 HVSI 570
             ++
Sbjct: 249 RGNV 252

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 37/122 (30%), Positives = 63/122 (51%)
 Frame = +1

Query: 100 NLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILI 279
           N  N +    LHLA + GH +    L+     +    + G+T LH     G   V R L+
Sbjct: 39  NTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELV 98

Query: 280 SVSSDINQQNQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSE 459
           +  +++N Q+Q G T L++AA     ++ K L+E+GAN ++      TPL VA+++ H  
Sbjct: 99  NYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHEN 158

Query: 460 II 465
           ++
Sbjct: 159 VV 160

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 41/148 (27%), Positives = 78/148 (52%)
 Frame = +1

Query: 31  LHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINAQN 210
           LH AA    ++T   L Q    P++++ + FTPLH+A    +    + L+  GA +N   
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 236

Query: 211 RFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVESGA 390
           + G TPLH   R G+  + R+L+   + I  + ++  T LH AA     +I+++L++ GA
Sbjct: 237 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA 296

Query: 391 NLDIRNIQNETPLDVAIKKNHSEIIDIL 474
            +  +     +P+ +A + +H + + +L
Sbjct: 297 PIQAKTKNGLSPIHMAAQGDHLDCVRLL 324

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 35/123 (28%), Positives = 64/123 (52%)
 Frame = +1

Query: 139 AVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNG 318
           A + G+     + ++ G DIN  N+ G   LH   + GH  +   L+     +    + G
Sbjct: 19  AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 78

Query: 319 DTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSN 498
           +T+LHIAA   + ++ + LV  GAN++ ++ +  TPL +A ++NH E++  L  +  + N
Sbjct: 79  NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 138

Query: 499 QKT 507
             T
Sbjct: 139 VAT 141
>sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G)
          Length = 4377

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 53/150 (35%), Positives = 79/150 (52%)
 Frame = +1

Query: 25  TPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
           TPLH +A  G +  V+ L Q G  PN    S +TPLHL+ + GH      L+  GA ++ 
Sbjct: 501 TPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 560

Query: 205 QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
             + G TPLH   +YG   V+ +L+  S+  +   ++G T LH+AA    +K+  LL++ 
Sbjct: 561 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 620

Query: 385 GANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           GA+         TPL +A KKN  +I   L
Sbjct: 621 GASPHAAAKNGYTPLHIAAKKNQMDIATTL 650

 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 50/152 (32%), Positives = 76/152 (50%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           G TP+H AA+ G+   V  L   G  PN  N    T LH+A + G  +  R L++ GA +
Sbjct: 433 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 492

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
            A+ +   TPLH   R G A + + L+   +  N    +G T LH++A      +   L+
Sbjct: 493 EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLL 552

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           + GA+L I   +  TPL VA K    E+ ++L
Sbjct: 553 DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 57/192 (29%), Positives = 89/192 (46%), Gaps = 6/192 (3%)
 Frame = +1

Query: 19   GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
            G   +H AA +G+   V  L       NL N S  TPLHLA Q         L+  GA +
Sbjct: 664  GIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHV 723

Query: 199  NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
            +AQ + G TPLH G  YG+  +   L+  S+ +N + +NG T LH AA      I  +L+
Sbjct: 724  DAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLL 783

Query: 379  ESGANLDIRNIQNETPLDVAIKKNHSEIIDILK------MSICSSNQKTVSFLPENIREN 540
            ++ A+ +   +   T L +A +  +  ++D LK      M+  +  +K    +PE + E 
Sbjct: 784  QNNASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPETMNEV 843

Query: 541  FSVQSRHVSIPN 576
              +    V   N
Sbjct: 844  LDMSDDEVRKAN 855

 Score = 87.4 bits (215), Expect = 4e-17
 Identities = 50/166 (30%), Positives = 80/166 (48%)
 Frame = +1

Query: 16   HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
            +G TPLH AA K        L + G   N V       +HLA Q GH      L+   A+
Sbjct: 630  NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN 689

Query: 196  INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
            +N  N+ G TPLH   +     V+ +L++  + ++ Q + G T LH+       KI   L
Sbjct: 690  VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFL 749

Query: 376  VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVS 513
            ++  A ++ +     TPL  A ++ H+ II++L  +  S N+ TV+
Sbjct: 750  LQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVN 795

 Score = 86.7 bits (213), Expect = 7e-17
 Identities = 50/163 (30%), Positives = 80/163 (49%)
 Frame = +1

Query: 19   GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
            G TPLH AA     +    L   G  P+    + +TPLH+A +         L++ GAD 
Sbjct: 598  GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 657

Query: 199  NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
            NA  R G   +H   + GH  +  +L+  ++++N  N++G T LH+AA   R  + ++LV
Sbjct: 658  NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLV 717

Query: 379  ESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKT 507
              GA++D +     TPL V     + +I++ L       N KT
Sbjct: 718  NQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKT 760

 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 49/163 (30%), Positives = 80/163 (49%)
 Frame = +1

Query: 25  TPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
           T LH AA  G+ +  + L      PN    + FTPLH+A +    +    L+K GA I A
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQA 428

Query: 205 QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
               G TP+H     GH  +   L+   +  N  N  G+T+LH+AA   + ++ + LV+ 
Sbjct: 429 VTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQD 488

Query: 385 GANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVS 513
           GA ++ +   ++TPL ++ +   ++I+  L     S N  T S
Sbjct: 489 GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTS 531

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 39/125 (31%), Positives = 74/125 (59%)
 Frame = +1

Query: 100 NLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILI 279
           N+ N +    LHLA + GH +    L++  A+++A  + G+T LH     G A V ++L+
Sbjct: 68  NICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLV 127

Query: 280 SVSSDINQQNQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSE 459
           +  +++N Q+QNG T L++AA     ++ K L+++GA+  +      TPL VA+++ H +
Sbjct: 128 TNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQ 187

Query: 460 IIDIL 474
           ++ +L
Sbjct: 188 VVSLL 192

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 48/153 (31%), Positives = 75/153 (49%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           +G TPLH A  K   + +E L + G     V  S  TP+H+A   GH      L+  GA 
Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 458

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
            N  N  G+T LH   R G A V R L+   + +  + ++  T LHI+A L +  I + L
Sbjct: 459 PNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQL 518

Query: 376 VESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           ++ GA+ +       TPL ++ ++ H ++   L
Sbjct: 519 LQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 551

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 43/150 (28%), Positives = 77/150 (51%)
 Frame = +1

Query: 25  TPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
           TPLH A+ +G +  V+ L   G   +       TPLH   + GH Q    L+   A I +
Sbjct: 270 TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILS 329

Query: 205 QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
           + + G +PLH   +  H    ++L+  +  ++    +  T+LH+AA     K+ K+L++ 
Sbjct: 330 KTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDK 389

Query: 385 GANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
            AN + + +   TPL +A KKN  +++++L
Sbjct: 390 KANPNAKALNGFTPLHIACKKNRIKVMELL 419

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 51/184 (27%), Positives = 89/184 (48%), Gaps = 29/184 (15%)
 Frame = +1

Query: 10  STHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLI--- 180
           S +G TPL+ AA + + + V++L   G   +L     FTPL +A+Q GH+Q    L+   
Sbjct: 137 SQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEND 196

Query: 181 -------------------KCGA-----DINA--QNRFGDTPLHTGVRYGHAGVSRILIS 282
                              K  A     D NA  +++ G TPLH    YG+  V+ +L++
Sbjct: 197 TKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLN 256

Query: 283 VSSDINQQNQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEI 462
            ++ ++   +N  T LH+A+      + KLL++ GA +D +     TPL    +  H ++
Sbjct: 257 RAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQV 316

Query: 463 IDIL 474
           +++L
Sbjct: 317 VEML 320

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 45/155 (29%), Positives = 78/155 (50%)
 Frame = +1

Query: 10  STHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCG 189
           +T G TPLH +A +G+     +L   G   ++     FTPLH+A + G  +    L++  
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 588

Query: 190 ADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITK 369
           A  +A  + G TPLH    Y +  V+ +L+   +  +   +NG T LHIAA   +  I  
Sbjct: 589 ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 648

Query: 370 LLVESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
            L+E GA+ +    Q    + +A ++ H +++ +L
Sbjct: 649 TLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683

 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 50/164 (30%), Positives = 74/164 (45%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           G TPLH  A  G+ Q VE L            +  +PLH+A QG H    + L++    +
Sbjct: 301 GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPV 360

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           +       T LH     GH  V+++L+   ++ N +  NG T LHIA    R K+ +LL+
Sbjct: 361 DDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL 420

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTV 510
           + GA++        TP+ VA    H  I+  L     S N   V
Sbjct: 421 KHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 464

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 37/112 (33%), Positives = 65/112 (58%)
 Frame = +1

Query: 139 AVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNG 318
           A + GH +   + IK G DIN  N+ G   LH   + GH  V   L+   ++++   + G
Sbjct: 48  AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107

Query: 319 DTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           +T+LHIA+   + ++ K+LV +GAN++ ++    TPL +A ++NH E++  L
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFL 159

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 43/158 (27%), Positives = 75/158 (47%)
 Frame = +1

Query: 1   IQDSTHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLI 180
           +  + +G +PLH A    +   V+ L Q     + V     T LH+A   GH +  + L+
Sbjct: 328 LSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLL 387

Query: 181 KCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRK 360
              A+ NA+   G TPLH   +     V  +L+   + I    ++G T +H+AA +    
Sbjct: 388 DKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVN 447

Query: 361 ITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           I   L+  GA+ +  N++ ET L +A +   +E++  L
Sbjct: 448 IVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 485

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 44/152 (28%), Positives = 74/152 (48%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           GNT LH A+  G ++ V+ L   G   N  + + FTPL++A Q  H +  + L+  GA  
Sbjct: 107 GNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQ 166

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           +     G TPL   ++ GH  V  +L+    + + + +    +LHIAA     K   LL+
Sbjct: 167 SLATEDGFTPLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKAAALLL 222

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           ++  N D+ +    TPL +A    +  +  +L
Sbjct: 223 QNDNNADVESKSGFTPLHIAAHYGNINVATLL 254

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 16/47 (34%), Positives = 27/47 (57%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGH 156
           +G TPLH+AA +G++  +  L Q    PN +  +  T L +A + G+
Sbjct: 762 NGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGY 808
>sp|Q92625|ANKS1_HUMAN Ankyrin repeat and SAM domain-containing protein 1 (Odin)
          Length = 1134

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 59/170 (34%), Positives = 86/170 (50%), Gaps = 3/170 (1%)
 Frame = +1

Query: 7   DSTHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKC 186
           DST G TPLH AA  G+   VE L +   L N+ +     PLHLA   G  Q  R LI  
Sbjct: 77  DST-GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQ 135

Query: 187 GAD---INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRR 357
           G     +N QN   +T LH   +YGH  V ++L+   +D   +N   +T L +AA   R 
Sbjct: 136 GPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRL 195

Query: 358 KITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKT 507
           ++ K+L+ +  NL   N +  TPL +A +  H  ++ +L  +   SN +T
Sbjct: 196 EVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQT 245

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 46/144 (31%), Positives = 73/144 (50%), Gaps = 5/144 (3%)
 Frame = +1

Query: 58  SQTVEYLCQIGRLPNL--VNYSLFTPLHLAVQGGHNQTTRNLIKCGADINAQNRFGDTPL 231
           S  +  L  + R PN+  V+ + +TPLH A   GH      L++  A  N  +  G  PL
Sbjct: 58  SHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPL 117

Query: 232 HTGVRYGHAGVSRILISVSSD---INQQNQNGDTSLHIAAALKRRKITKLLVESGANLDI 402
           H     G A + R+LI        +N+QN + +T+LH AA     ++ K+L+E   +  +
Sbjct: 118 HLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTM 177

Query: 403 RNIQNETPLDVAIKKNHSEIIDIL 474
           RN + ETPLD+A      E++ +L
Sbjct: 178 RNNKFETPLDLAALYGRLEVVKML 201

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 41/143 (28%), Positives = 72/143 (50%)
 Frame = +1

Query: 4   QDSTHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIK 183
           + +    T LH AA  G+++ V+ L +    P + N    TPL LA   G  +  + L+ 
Sbjct: 144 EQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLN 203

Query: 184 CGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKI 363
              ++ + N    TPLH   R GH  V ++L+    D N Q + G ++LH AA   +  +
Sbjct: 204 AHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDV 262

Query: 364 TKLLVESGANLDIRNIQNETPLD 432
            ++L+ +G +++I++    T LD
Sbjct: 263 VQILLAAGTDVNIKDNHGLTALD 285

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
 Frame = +1

Query: 187 GADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKIT 366
           G ++N  +  G TPLH     GH  V  +L+   +  N  +  G   LH+AA     +I 
Sbjct: 70  GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129

Query: 367 KLLVESGAN---LDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVSF 516
           +LL+  G +   ++ +N  NET L  A +  H+E++ +L   +     +   F
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKF 182
>sp|Q02357|ANK1_MOUSE Ankyrin-1 (Erythrocyte ankyrin)
          Length = 1862

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 62/186 (33%), Positives = 93/186 (50%), Gaps = 5/186 (2%)
 Frame = +1

Query: 7    DSTHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKC 186
            +S  G TPLH AA +G+++ V  L       NL N S  TPLHL  Q GH      LIK 
Sbjct: 627  ESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADVLIKH 686

Query: 187  GADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKIT 366
            G  ++A  R G TPLH    YG+  + + L+   +D+N + + G + LH AA      I 
Sbjct: 687  GVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIV 746

Query: 367  KLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKM-----SICSSNQKTVSFLPENI 531
             LL+++GA+ +  +    TPL +A +  +  + D+LK+     S+   + K     PE +
Sbjct: 747  TLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLKVVTDETSVVLVSDKHRMSYPETV 806

Query: 532  RENFSV 549
             E   V
Sbjct: 807  DEILDV 812

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 51/146 (34%), Positives = 78/146 (53%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           +G TPLH A  K + + +E L + G   + V  S  TPLH+A   GH    +NL++ GA 
Sbjct: 366 NGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 425

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
            N  N   +TPLH   R GH  V++ L+   +  N + ++  T LH AA +    + KLL
Sbjct: 426 PNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLL 485

Query: 376 VESGANLDIRNIQNETPLDVAIKKNH 453
           +E+GA+ ++      TPL  A ++ H
Sbjct: 486 LENGASPNLATTAGHTPLHTAAREGH 511

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 49/163 (30%), Positives = 85/163 (52%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           +G +P+H AA   +   V  L Q     + +     TPLH+A   GH++  + L+  GA 
Sbjct: 300 NGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK 359

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
            N++   G TPLH   +  H  V  +L+   + I+   ++G T LH+A+ +    I K L
Sbjct: 360 PNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNL 419

Query: 376 VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQK 504
           ++ GA+ ++ N++ ETPL +A +  H+E+   L  +   +N K
Sbjct: 420 LQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAK 462

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 51/152 (33%), Positives = 76/152 (50%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           G TPLH A++ G+   V+ L Q G  PN+ N  + TPLH+A + GH +  + L++  A  
Sbjct: 400 GLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKA 459

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           NA+ +   TPLH   R GH G+ ++L+   +  N     G T LH AA          L+
Sbjct: 460 NAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALL 519

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           E  A+      +  TPL VA K     + ++L
Sbjct: 520 EKEASQACMTKKGFTPLHVAAKYGKVRLAELL 551

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 52/168 (30%), Positives = 86/168 (51%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           +G TPLH A+ +G    V  L   G           TPLH A + GH + +  L+  GA 
Sbjct: 234 NGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAP 293

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
           I A+ + G +P+H   +  H    R+L+  +++I+    +  T LH+AA     ++ K+L
Sbjct: 294 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVL 353

Query: 376 VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVSFL 519
           ++ GA  + R +   TPL +A KKNH  ++++L  +  S +  T S L
Sbjct: 354 LDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGL 401

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 51/163 (31%), Positives = 82/163 (50%)
 Frame = +1

Query: 25  TPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
           TPLH AA  G+ +  + L   G  PN    + FTPLH+A +  H +    L+K GA I+A
Sbjct: 336 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDA 395

Query: 205 QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
               G TPLH     GH  + + L+   +  N  N   +T LH+AA     ++ K L+++
Sbjct: 396 VTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 455

Query: 385 GANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVS 513
            A  + +   ++TPL  A +  H+ ++ +L  +  S N  T +
Sbjct: 456 KAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLATTA 498

 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 54/162 (33%), Positives = 79/162 (48%)
 Frame = +1

Query: 25  TPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
           TPLH AA  G++  V+ L + G  PNL   +  TPLH A + GH  T   L++  A    
Sbjct: 468 TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 527

Query: 205 QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
             + G TPLH   +YG   ++ +L+   +  N   +NG T LH+A       I KLL+  
Sbjct: 528 MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPR 587

Query: 385 GANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTV 510
           G +         TPL +A K+N  E+   L     S+N ++V
Sbjct: 588 GGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESV 629

 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 51/162 (31%), Positives = 83/162 (51%)
 Frame = +1

Query: 16   HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
            +G TPLH AA +   +    L Q G   N  +    TPLHLA Q GH +    L+   A+
Sbjct: 597  NGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQAN 656

Query: 196  INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
             N  N+ G TPLH   + GH  V+ +LI     ++   + G T LH+A+     K+ K L
Sbjct: 657  GNLGNKSGLTPLHLVSQEGHVLVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFL 716

Query: 376  VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQ 501
            ++  A+++ +     +PL  A ++ H++I+ +L  +  S N+
Sbjct: 717  LQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNE 758

 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 48/163 (29%), Positives = 85/163 (52%)
 Frame = +1

Query: 10  STHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCG 189
           +T G+TPLH AA +G+  T   L +       +    FTPLH+A + G  +    L++  
Sbjct: 496 TTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHD 555

Query: 190 ADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITK 369
           A  NA  + G TPLH  V + +  + ++L+      +    NG T LHIAA   + ++ +
Sbjct: 556 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVAR 615

Query: 370 LLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSN 498
            L++ G + +  ++Q  TPL +A ++ H+E++ +L     + N
Sbjct: 616 SLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGN 658

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 55/184 (29%), Positives = 85/184 (46%), Gaps = 29/184 (15%)
 Frame = +1

Query: 10  STHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCG 189
           S  G TPL+ AA + + + V++L + G   N+     FTPL +A+Q GH     +LI  G
Sbjct: 104 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 163

Query: 190 A---------DINAQN--------------------RFGDTPLHTGVRYGHAGVSRILIS 282
                      I A+N                    + G TPLH    Y +  V+++L++
Sbjct: 164 TKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN 223

Query: 283 VSSDINQQNQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEI 462
             + +N   QNG T LHIA+      + +LL++ GA ++ R     TPL  A +  H  I
Sbjct: 224 RGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRI 283

Query: 463 IDIL 474
            +IL
Sbjct: 284 SEIL 287

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 54/203 (26%), Positives = 97/203 (47%), Gaps = 7/203 (3%)
 Frame = +1

Query: 16   HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
            +G TPLH A        V+ L   G  P+   ++ +TPLH+A +    +  R+L++ G  
Sbjct: 564  NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGS 623

Query: 196  INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
             NA++  G TPLH   + GH  +  +L+S  ++ N  N++G T LH+ +      +  +L
Sbjct: 624  ANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADVL 683

Query: 376  VESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKT-VSFLP------ENIR 534
            ++ G  +D       TPL VA    + +++  L       N KT + + P      +   
Sbjct: 684  IKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHT 743

Query: 535  ENFSVQSRHVSIPNEMCSVVNTP 603
            +  ++  ++ + PNE+ S   TP
Sbjct: 744  DIVTLLLKNGASPNEVSSNGTTP 766

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 46/152 (30%), Positives = 71/152 (46%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           G TPLH AA  G  +  E L +    PN    +  TPLH+AV   +    + L+  G   
Sbjct: 532 GFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP 591

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           ++    G TPLH   +     V+R L+      N ++  G T LH+AA     ++  LL+
Sbjct: 592 HSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLL 651

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
              AN ++ N    TPL +  ++ H  + D+L
Sbjct: 652 SKQANGNLGNKSGLTPLHLVSQEGHVLVADVL 683

 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 52/184 (28%), Positives = 89/184 (48%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           GNT LH AA  G  + V  L   G   N  +   FTPL++A Q  H +  + L++ GA+ 
Sbjct: 74  GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQ 133

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           N     G TPL   ++ GH  V   LI+  +    + +    +LHIAA     +   +L+
Sbjct: 134 NVATEDGFTPLAVALQQGHENVVAHLINYGT----KGKVRLPALHIAARNDDTRTAAVLL 189

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVSFLPENIRENFSVQSR 558
           ++  N D+ +    TPL +A    H E +++ ++ +  +   +V+F P+N      + SR
Sbjct: 190 QNDPNPDVLSKTGFTPLHIAA---HYENLNVAQLLL--NRGASVNFTPQNGITPLHIASR 244

Query: 559 HVSI 570
             ++
Sbjct: 245 RGNV 248

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 37/122 (30%), Positives = 63/122 (51%)
 Frame = +1

Query: 100 NLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILI 279
           N  N +    LHLA + GH +    L+     +    + G+T LH     G   V R L+
Sbjct: 35  NTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELV 94

Query: 280 SVSSDINQQNQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSE 459
           +  +++N Q+Q G T L++AA     ++ K L+E+GAN ++      TPL VA+++ H  
Sbjct: 95  NYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHEN 154

Query: 460 II 465
           ++
Sbjct: 155 VV 156

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 41/148 (27%), Positives = 78/148 (52%)
 Frame = +1

Query: 31  LHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINAQN 210
           LH AA    ++T   L Q    P++++ + FTPLH+A    +    + L+  GA +N   
Sbjct: 173 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 232

Query: 211 RFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVESGA 390
           + G TPLH   R G+  + R+L+   + I  + ++  T LH AA     +I+++L++ GA
Sbjct: 233 QNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGA 292

Query: 391 NLDIRNIQNETPLDVAIKKNHSEIIDIL 474
            +  +     +P+ +A + +H + + +L
Sbjct: 293 PIQAKTKNGLSPIHMAAQGDHLDCVRLL 320

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 35/123 (28%), Positives = 64/123 (52%)
 Frame = +1

Query: 139 AVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNG 318
           A + G+     + ++ G DIN  N+ G   LH   + GH  +   L+     +    + G
Sbjct: 15  AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 74

Query: 319 DTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSN 498
           +T+LHIAA   + ++ + LV  GAN++ ++ +  TPL +A ++NH E++  L  +  + N
Sbjct: 75  NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 134

Query: 499 QKT 507
             T
Sbjct: 135 VAT 137
>sp|Q9WV06|ANR2_MOUSE Ankyrin repeat domain protein 2 (Skeletal muscle ankyrin repeat
           protein) (mArpp)
          Length = 328

 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 50/137 (36%), Positives = 79/137 (57%)
 Frame = +1

Query: 25  TPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
           T LH A+ +G+ + +E L + G   +  +    T +H A +GGH +  R L   GAD N 
Sbjct: 152 TALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNV 211

Query: 205 QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
           +++   TPLH  VR GH  +    +S+  DIN +++ GD++LH A  L R KI KLL+  
Sbjct: 212 RDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLH 271

Query: 385 GANLDIRNIQNETPLDV 435
           GA++  +N+  +TP D+
Sbjct: 272 GADMMAKNLAGKTPTDL 288

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 37/142 (26%), Positives = 68/142 (47%), Gaps = 3/142 (2%)
 Frame = +1

Query: 124 TPLHLAVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQ 303
           T L  AV+G      + L   G   +  + F  T LH     GH  +   L+   + ++ 
Sbjct: 120 TFLKAAVEGKMKVIDKYLAD-GGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDF 178

Query: 304 QNQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIID---IL 474
           Q++   T++H A      ++ +LL   GA+ ++R+    TPL VA++  H EI++    L
Sbjct: 179 QDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSL 238

Query: 475 KMSICSSNQKTVSFLPENIREN 540
            + I + +++  S L + +R N
Sbjct: 239 GLDINAKDREGDSALHDAVRLN 260
>sp|Q59H18|TNI3K_HUMAN Serine/threonine-protein kinase TNNI3K (TNNI3-interacting kinase)
           (Cardiac ankyrin repeat kinase)
          Length = 936

 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 54/158 (34%), Positives = 80/158 (50%), Gaps = 2/158 (1%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           +G T LH A +K  ++ +  L   G     V Y   T LH+A   GH +    L++ GA+
Sbjct: 201 NGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 260

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
           +N Q+    TPLH    YGH  V+R+L+   +D+N   + GD  LH+A+A     I KLL
Sbjct: 261 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 320

Query: 376 VESGANLDIRNIQNE--TPLDVAIKKNHSEIIDILKMS 483
           +E G+  D+    NE   PL    +  H +I+  L  S
Sbjct: 321 MEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQS 358

 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 58/194 (29%), Positives = 84/194 (43%), Gaps = 41/194 (21%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           G T LH A   G+ +  + L Q G   N+ +   FTPLH+A   GH Q TR L+K GAD+
Sbjct: 235 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 294

Query: 199 NAQNRFGDTPLHTG-----------------------------------VRYGHAGVSRI 273
           N     GD PLH                                      R+GH  + + 
Sbjct: 295 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 354

Query: 274 LISVSSDINQQ----NQNGDTSLHIAAALKRRKITKLLVE-SGA-NLDIRNIQNETPLDV 435
           L+   SD+  Q    N  GDT LH+A    + ++ K +++ SG  +L   NI +ET    
Sbjct: 355 LL--QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHS 412

Query: 436 AIKKNHSEIIDILK 477
           A    + + ID++K
Sbjct: 413 AC--TYGKSIDLVK 424

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 36/116 (31%), Positives = 56/116 (48%), Gaps = 1/116 (0%)
 Frame = +1

Query: 130 LHLA-VQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQ 306
           LHL  + GG     R L+  G   +   R G T LH  V   +A +   L+   +DI Q 
Sbjct: 172 LHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQV 231

Query: 307 NQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
              G T+LHIA      +   +L++ GAN++I++    TPL +A    H ++  +L
Sbjct: 232 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLL 287

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 48/206 (23%), Positives = 82/206 (39%), Gaps = 7/206 (3%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLF--TPLHLAVQGGHNQTTRNLIKCG 189
           +G+TPLH A + G  +  + + QI    +L   ++F  T  H A   G +    +L+K  
Sbjct: 370 YGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSI---DLVKFL 426

Query: 190 AD-----INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKR 354
            D     IN Q R G T LH+   +GH  + + L+   +D+N                  
Sbjct: 427 LDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN------------------ 468

Query: 355 RKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVSFLPENIR 534
                 LV    +        +T L  A +K H  I+ +LK       ++    LP N  
Sbjct: 469 ------LVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLK-----HYKRPQDELPCNEY 517

Query: 535 ENFSVQSRHVSIPNEMCSVVNTPEQK 612
                   +VS+P+ +  + +  ++K
Sbjct: 518 SQPGGDGSYVSVPSPLGKIKSMTKEK 543
>sp|P57078|RIPK4_HUMAN Serine/threonine-protein kinase RIPK4 (Receptor-interacting
            serine/threonine-protein kinase 4) (Ankyrin repeat domain
            protein 3) (PKC-delta-interacting protein kinase)
          Length = 832

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 55/150 (36%), Positives = 76/150 (50%), Gaps = 1/150 (0%)
 Frame = +1

Query: 28   PLHEAAWKGYSQTVEYLC-QIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
            PLH AAW+G+   V+ L  Q G   N       TPLHLA Q GH +  R LI   +D+N 
Sbjct: 621  PLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 680

Query: 205  QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
             +    TPLH     GH   +R+L+   +       +G T+LH+AA        KLLVE 
Sbjct: 681  CSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEE 740

Query: 385  GANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
             A++  R   N+T L +A    HSE+++ L
Sbjct: 741  KADVLARGPLNQTALHLAAAHGHSEVVEEL 770

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 48/166 (28%), Positives = 82/166 (49%)
 Frame = +1

Query: 19   GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
            G TPLH AA +G+ +    L  +    N+ +    TPLH+A + GH  T R L+  GA  
Sbjct: 652  GRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGK 711

Query: 199  NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
             A    G T LH   R GH    ++L+   +D+  +     T+LH+AAA    ++ + LV
Sbjct: 712  EAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV 771

Query: 379  ESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVSF 516
             +   +D+ + Q  + L +A +  H++ ++ L       N +++ F
Sbjct: 772  SADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKF 816

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 38/115 (33%), Positives = 62/115 (53%)
 Frame = +1

Query: 130 LHLAVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQN 309
           LHLAV+ G  +  + L+   A+ N  NR G TPLH  V     GV  +L++    +N ++
Sbjct: 490 LHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKD 549

Query: 310 QNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
           ++  T+LH AA       T+LL+E  A+++  + +  TP+ VA +     I+ IL
Sbjct: 550 EDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 604

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 51/192 (26%), Positives = 82/192 (42%), Gaps = 34/192 (17%)
 Frame = +1

Query: 19   GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAV------------------ 144
            G + LH A   G  +  ++L      PNL N    TPLH+AV                  
Sbjct: 486  GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 545

Query: 145  ---------------QGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILI 279
                           Q G   +TR L++  A +N  +  G TP+H   ++G   + RIL+
Sbjct: 546  NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 605

Query: 280  SVSSDINQQNQNGDTSLHIAAALKRRKITKLLV-ESGANLDIRNIQNETPLDVAIKKNHS 456
                D++ Q ++    LH AA      I KLL  + G +++ + +   TPL +A ++ H 
Sbjct: 606  RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHY 665

Query: 457  EIIDILKMSICS 492
             +  IL + +CS
Sbjct: 666  RVARIL-IDLCS 676

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 18/71 (25%), Positives = 38/71 (53%)
 Frame = +1

Query: 292 DINQQNQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDI 471
           D++    +G + LH+A    + +  K L+ + AN ++ N +  TPL +A+++    ++++
Sbjct: 478 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 537

Query: 472 LKMSICSSNQK 504
           L     S N K
Sbjct: 538 LLARKISVNAK 548
>sp|Q5RF15|TNI3K_PONPY Serine/threonine-protein kinase TNNI3K (TNNI3-interacting kinase)
          Length = 618

 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 53/155 (34%), Positives = 79/155 (50%), Gaps = 2/155 (1%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           +G T LH A +K  ++ +  L   G     V Y   T LH+A   GH +    L++ GA+
Sbjct: 100 NGFTALHLAVYKDNAELITSLLHGGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGAN 159

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLL 375
           +N Q+    TPLH    YGH  V+R+L+   +D+N   + GD  LH+A+A     I KLL
Sbjct: 160 VNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 219

Query: 376 VESGANLDIRNIQNE--TPLDVAIKKNHSEIIDIL 474
           +E G+  D+    NE   PL    +  H +I+  L
Sbjct: 220 MEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYL 254

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 55/192 (28%), Positives = 82/192 (42%), Gaps = 39/192 (20%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           G T LH A   G+ +  + L Q G   N+ +   FTPLH+A   GH Q TR L+K GAD+
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193

Query: 199 NAQNRFGDTPLHTG-----------------------------------VRYGHAGVSRI 273
           N     GD PLH                                      R+GH  + + 
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 253

Query: 274 LISVSSDINQQ--NQNGDTSLHIAAALKRRKITKLLVE-SGA-NLDIRNIQNETPLDVAI 441
           L+    ++     N  GDT LH+A    + ++ K +++ SG  +L   NI +ET    A 
Sbjct: 254 LLQNDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSAC 313

Query: 442 KKNHSEIIDILK 477
              + + ID++K
Sbjct: 314 --TYGKSIDLVK 323

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 1/116 (0%)
 Frame = +1

Query: 130 LHLA-VQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQ 306
           LHL  + GG+    R L+  G   +   R G T LH  V   +A +   L+   +DI Q 
Sbjct: 71  LHLCCICGGNKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHGGADIQQV 130

Query: 307 NQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
              G T+LHIA      +   +L++ GAN++I++    TPL +A    H ++  +L
Sbjct: 131 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLL 186

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 48/206 (23%), Positives = 82/206 (39%), Gaps = 7/206 (3%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLF--TPLHLAVQGGHNQTTRNLIKCG 189
           +G+TPLH A + G  +  + + QI    +L   ++F  T  H A   G +    +L+K  
Sbjct: 269 YGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSI---DLVKFL 325

Query: 190 AD-----INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKR 354
            D     IN Q R G T LH+   +GH  + + L+   +D+N                  
Sbjct: 326 LDQNVININHQGRDGHTGLHSACYHGHIHLVQFLLDNGADMN------------------ 367

Query: 355 RKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICSSNQKTVSFLPENIR 534
                 LV    +        +T L  A +K H  I+ +LK       ++    LP N  
Sbjct: 368 ------LVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLK-----HYKRPQDELPCNEY 416

Query: 535 ENFSVQSRHVSIPNEMCSVVNTPEQK 612
                   +VS+P+ +  + +  ++K
Sbjct: 417 SQPGGDGSYVSVPSPLGKIKSMTKEK 442
>sp|Q80YE7|DAPK1_MOUSE Death-associated protein kinase 1 (DAP kinase 1)
          Length = 1442

 Score = 90.1 bits (222), Expect = 7e-18
 Identities = 49/158 (31%), Positives = 82/158 (51%)
 Frame = +1

Query: 19  GNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADI 198
           G T LH AA  G++  V+ LC  G  P+  +    TPLH A   G+    + L + G ++
Sbjct: 445 GETALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSVAKALCEVGCNV 504

Query: 199 NAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLV 378
           N +NR G+TPL T    G+  +   L    +D+N  +++G  +LH+A    + ++ K L+
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNASDKDGHIALHLAVRRCQMEVIKTLL 564

Query: 379 ESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSICS 492
             G+ +D ++    TPL VA K   + I+  L  + C+
Sbjct: 565 GHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCEASCN 602

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 52/150 (34%), Positives = 76/150 (50%)
 Frame = +1

Query: 25  TPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGADINA 204
           TPLH AAW GY    + LC++G   N+ N    TPL  A   G++     L + GAD+NA
Sbjct: 480 TPLHCAAWHGYYSVAKALCEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNA 539

Query: 205 QNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKITKLLVES 384
            ++ G   LH  VR     V + L+   S ++ Q+++G+T LH+A       I   L E+
Sbjct: 540 SDKDGHIALHLAVRRCQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCEA 599

Query: 385 GANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
             NLDI N    TPL +A      +++  L
Sbjct: 600 SCNLDISNKYGRTPLHLAANNGILDVVRYL 629

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 49/157 (31%), Positives = 84/157 (53%)
 Frame = +1

Query: 4   QDSTHGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIK 183
           Q + HG  PL  AA  G  Q ++ L + G   ++ +      ++ A + GH  T + L +
Sbjct: 374 QPNKHGTPPLLIAAGCGNIQMLQLLIKRGSRIDVQDKGGSNAIYWASRHGHVDTLKFLNE 433

Query: 184 CGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQNQNGDTSLHIAAALKRRKI 363
               ++ +++ G+T LH   RYGHA V ++L S  S+ + Q++  +T LH AA      +
Sbjct: 434 NKCPLDVKDKSGETALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSV 493

Query: 364 TKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDIL 474
            K L E G N++I+N + ETPL  A  + + +I++ L
Sbjct: 494 AKALCEVGCNVNIKNREGETPLLTASARGYHDIVECL 530

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 36/126 (28%), Positives = 65/126 (51%)
 Frame = +1

Query: 127 PLHLAVQGGHNQTTRNLIKCGADINAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQQ 306
           PL +A   G+ Q  + LIK G+ I+ Q++ G   ++   R+GH    + L      ++ +
Sbjct: 382 PLLIAAGCGNIQMLQLLIKRGSRIDVQDKGGSNAIYWASRHGHVDTLKFLNENKCPLDVK 441

Query: 307 NQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDVAIKKNHSEIIDILKMSI 486
           +++G+T+LH+AA      + +LL   G+N D ++ + ETPL  A    +  +   L    
Sbjct: 442 DKSGETALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSVAKALCEVG 501

Query: 487 CSSNQK 504
           C+ N K
Sbjct: 502 CNVNIK 507

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 31/96 (32%), Positives = 42/96 (43%)
 Frame = +1

Query: 16  HGNTPLHEAAWKGYSQTVEYLCQIGRLPNLVNYSLFTPLHLAVQGGHNQTTRNLIKCGAD 195
           HGNTPLH A   G +  V  LC+     ++ N    TPLHLA   G     R L   GA+
Sbjct: 576 HGNTPLHVACKDGSAPIVVALCEASCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGAN 635

Query: 196 INAQNRFGDTPLHTGVRYGHAGVSRILISVSSDINQ 303
           + A    G T         H  V+ +L  +  D ++
Sbjct: 636 VEALTSDGKTAEDLAKAEQHEHVAGLLARLRKDTHR 671

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 31/126 (24%), Positives = 61/126 (48%), Gaps = 1/126 (0%)
 Frame = +1

Query: 259 GVSRILISVSS-DINQQNQNGDTSLHIAAALKRRKITKLLVESGANLDIRNIQNETPLDV 435
           G+  +L S+SS D+NQ N++G   L IAA     ++ +LL++ G+ +D+++      +  
Sbjct: 359 GLQHLLGSLSSYDVNQPNKHGTPPLLIAAGCGNIQMLQLLIKRGSRIDVQDKGGSNAIYW 418

Query: 436 AIKKNHSEIIDILKMSICSSNQKTVSFLPENIRENFSVQSRHVSIPNEMCSVVNTPEQKP 615
           A +  H + +  L  + C  + K  S        + + +  H  +   +CS  + P+   
Sbjct: 419 ASRHGHVDTLKFLNENKCPLDVKDKS---GETALHVAARYGHADVVQLLCSFGSNPD--- 472

Query: 616 FRAKSE 633
           F+ K E
Sbjct: 473 FQDKEE 478
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.315    0.130    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,496,270
Number of Sequences: 369166
Number of extensions: 1880834
Number of successful extensions: 7203
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4629
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6065
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)