Planaria EST Database


DrC_02662

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02662
         (572 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O00463|TRAF5_HUMAN  TNF receptor-associated factor 5 (RIN...    69   8e-12
sp|Q13114|TRAF3_HUMAN  TNF receptor-associated factor 3 (CD4...    69   8e-12
sp|Q60803|TRAF3_MOUSE  TNF receptor-associated factor 3 (CD4...    69   8e-12
sp|P70191|TRAF5_MOUSE  TNF receptor-associated factor 5            65   9e-11
sp|Q12933|TRAF2_HUMAN  TNF receptor-associated factor 2 (Tum...    65   2e-10
sp|Q13077|TRAF1_HUMAN  TNF receptor-associated factor 1 (Eps...    64   2e-10
sp|Q9BUZ4|TRAF4_HUMAN  TNF receptor-associated factor 4 (Cys...    63   6e-10
sp|Q61382|TRAF4_MOUSE  TNF receptor-associated factor 4 (Cys...    63   6e-10
sp|P39428|TRAF1_MOUSE  TNF receptor-associated factor 1            62   8e-10
sp|Q9Y4K3|TRAF6_HUMAN  TNF receptor-associated factor 6 (Int...    62   8e-10
>sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84)
          Length = 557

 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 38/116 (32%), Positives = 66/116 (56%), Gaps = 8/116 (6%)
 Frame = +3

Query: 84  GEFEWKIENFAQQRRRT------NIYSESFYSHKNGYKMCLSVKIGNDDYA--DYVSVYF 239
           G+  WK+ ++  ++R        +I+S+SFY+ + GY++C    +  D      ++S+YF
Sbjct: 404 GKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYF 463

Query: 240 HLMRGEFDNDLLWPFKHAVTIDMINQMSGGAYESKTRKYDDDDPNHKGWNKPTTEI 407
            +MRGEFD+ L WPF+  VT+ +++Q SG     +T K    DPN   + +P  E+
Sbjct: 464 VVMRGEFDSLLQWPFRQRVTLMLLDQ-SGKKNIMETFK---PDPNSSSFKRPDGEM 515
>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
           associated protein) (LAP1) (CAP-1)
          Length = 568

 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 8/116 (6%)
 Frame = +3

Query: 84  GEFEWKIENFAQQRRRT------NIYSESFYSHKNGYKMCLSVKIGNDDYAD--YVSVYF 239
           G   WKI ++ ++++        ++YS+ FY+   GYKMC  V +  D      ++S++F
Sbjct: 416 GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFF 475

Query: 240 HLMRGEFDNDLLWPFKHAVTIDMINQMSGGAYESKTRKYDDDDPNHKGWNKPTTEI 407
            +MRGE+D  L WPFK  VT+ +++Q S   +     K    DPN   + KPT E+
Sbjct: 476 VIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFK---PDPNSSSFKKPTGEM 528
>sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (TRAFAMN)
          Length = 567

 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 8/116 (6%)
 Frame = +3

Query: 84  GEFEWKIENFAQQRRRT------NIYSESFYSHKNGYKMCLSVKIGNDDYAD--YVSVYF 239
           G   WKI ++ ++++        ++YS+ FY+   GYKMC  V +  D      ++S++F
Sbjct: 415 GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFF 474

Query: 240 HLMRGEFDNDLLWPFKHAVTIDMINQMSGGAYESKTRKYDDDDPNHKGWNKPTTEI 407
            +MRGE+D  L WPFK  VT+ +++Q S   +     K    DPN   + KPT E+
Sbjct: 475 VIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFK---PDPNSSSFKKPTGEM 527
>sp|P70191|TRAF5_MOUSE TNF receptor-associated factor 5
          Length = 558

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 34/116 (29%), Positives = 64/116 (55%), Gaps = 8/116 (6%)
 Frame = +3

Query: 84  GEFEWKIENFAQQRRRT------NIYSESFYSHKNGYKMCLSVKIGNDDYAD--YVSVYF 239
           G+  WK+ ++  ++R        +++S+ FY+ + GY++C    +  D      ++S+YF
Sbjct: 404 GKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYF 463

Query: 240 HLMRGEFDNDLLWPFKHAVTIDMINQMSGGAYESKTRKYDDDDPNHKGWNKPTTEI 407
            +MRGEFD+ L WPF+  VT+ +++Q     +  +T K    DPN   + +P  E+
Sbjct: 464 VVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFK---ADPNSSSFKRPDGEM 516
>sp|Q12933|TRAF2_HUMAN TNF receptor-associated factor 2 (Tumor necrosis factor type 2
           receptor-associated protein 3)
          Length = 501

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 37/104 (35%), Positives = 60/104 (57%), Gaps = 8/104 (7%)
 Frame = +3

Query: 30  NLQIKTIEMERITEKINFGEFEWKIENFAQQRRRT------NIYSESFYSHKNGYKMCLS 191
           +L+ K +EME  T     G F WKI +FA++R+         I+S +FY+ + GYKMCL 
Sbjct: 337 DLEQKVLEMEASTYD---GVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLR 393

Query: 192 VKIGND--DYADYVSVYFHLMRGEFDNDLLWPFKHAVTIDMINQ 317
           + +  D      ++S++F +M+G  D  L WPF   VT+ +++Q
Sbjct: 394 IYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ 437
>sp|Q13077|TRAF1_HUMAN TNF receptor-associated factor 1 (Epstein-Barr virus-induced
           protein 6)
          Length = 416

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 38/129 (29%), Positives = 70/129 (54%), Gaps = 26/129 (20%)
 Frame = +3

Query: 9   IDNEKINNLQIKTIEME-----------------RITEKINF-GEFEWKIENFAQQ---- 122
           +D E+I +L+ + +E++                 R+ E+ +F G F WKI N  ++    
Sbjct: 224 LDRERILSLEQRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHES 283

Query: 123 --RRRTNIYSESFYSHKNGYKMCLSVKIGNDDYAD--YVSVYFHLMRGEFDNDLLWPFKH 290
              R  +++S +FY+ K GYK+CL + +  D      ++S++  +MRGE+D  L WPF++
Sbjct: 284 ACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRN 343

Query: 291 AVTIDMINQ 317
            VT  +++Q
Sbjct: 344 KVTFMLLDQ 352
>sp|Q9BUZ4|TRAF4_HUMAN TNF receptor-associated factor 4 (Cysteine-rich domain associated
           with RING and Traf domains protein 1) (Malignant 62)
           (RING finger protein 83)
          Length = 470

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 39/129 (30%), Positives = 65/129 (50%), Gaps = 12/129 (9%)
 Frame = +3

Query: 51  EMERITEKINFGE---FEWKIENF------AQQRRRTNIYSESFYSHKNGYKMCLSVKIG 203
           E+ R  E+++ G      WKI ++      A+ +     +S +FY+HK GYK+ +S  + 
Sbjct: 294 ELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLN 353

Query: 204 NDDYAD--YVSVYFHLMRGEFDNDLLWPFKHAVTIDMINQMSGG-AYESKTRKYDDDDPN 374
            +   +  ++S+Y  ++ G FDN L WPF   VT  +++Q   G A      +    DPN
Sbjct: 354 GNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPN 413

Query: 375 HKGWNKPTT 401
            K + KP T
Sbjct: 414 WKNFQKPGT 422
>sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 (Cysteine-rich motif associated to
           RING and Traf domains protein 1)
          Length = 470

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 38/129 (29%), Positives = 64/129 (49%), Gaps = 12/129 (9%)
 Frame = +3

Query: 51  EMERITEKINFGE---FEWKIENF------AQQRRRTNIYSESFYSHKNGYKMCLSVKIG 203
           E+ R  E+++ G      WKI ++      A+ +     +S +FY+HK GYK+ +S  + 
Sbjct: 294 ELRRELEELSIGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSASLN 353

Query: 204 NDDYAD--YVSVYFHLMRGEFDNDLLWPFKHAVTIDMINQMSGG-AYESKTRKYDDDDPN 374
            +   +  ++S+Y  ++ G FDN L WP    VT  +++Q   G A      +    DPN
Sbjct: 354 GNGSGEGTHLSIYIRVLPGAFDNLLEWPLARRVTFSLLDQSDPGLAKPQHVTETFHPDPN 413

Query: 375 HKGWNKPTT 401
            K + KP T
Sbjct: 414 WKNFQKPGT 422
>sp|P39428|TRAF1_MOUSE TNF receptor-associated factor 1
          Length = 409

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 37/129 (28%), Positives = 69/129 (53%), Gaps = 26/129 (20%)
 Frame = +3

Query: 9   IDNEKINNLQIKTIEME-----------------RITEKINF-GEFEWKIENFAQQ---- 122
           +D E + +L+ + +E++                 R+ E+ +F G F WKI N  ++    
Sbjct: 217 LDREHLLSLEQRVVELQQTLAQKDQVLGKLEHSLRLMEEASFDGTFLWKITNVTKRCHES 276

Query: 123 --RRRTNIYSESFYSHKNGYKMCLSVKIGNDDYAD--YVSVYFHLMRGEFDNDLLWPFKH 290
              R  +++S +FY+ K GYK+CL + +  D      ++S++  +MRGE+D  L WPF++
Sbjct: 277 VCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRN 336

Query: 291 AVTIDMINQ 317
            VT  +++Q
Sbjct: 337 KVTFMLLDQ 345
>sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Interleukin 1 signal transducer)
           (RING finger protein 85)
          Length = 522

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 39/134 (29%), Positives = 69/134 (51%), Gaps = 9/134 (6%)
 Frame = +3

Query: 24  INNLQIKTIEMERITEKINFGEFEWKIENFA------QQRRRTNIYSESFYSHKNGYKMC 185
           I  L+ K  E+E   ++ N G + WKI NF       ++ +   I+S  FY+ K GYK+C
Sbjct: 334 IRTLEDKVAEIE--AQQCN-GIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLC 390

Query: 186 LSVKIG---NDDYADYVSVYFHLMRGEFDNDLLWPFKHAVTIDMINQMSGGAYESKTRKY 356
           + + +        A+Y+S++ H M+GE+D+ L WPF+  + + +++Q S         + 
Sbjct: 391 MRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQ-SEAPVRQNHEEI 449

Query: 357 DDDDPNHKGWNKPT 398
            D  P    + +PT
Sbjct: 450 MDAKPELLAFQRPT 463
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,739,590
Number of Sequences: 369166
Number of extensions: 906003
Number of successful extensions: 2516
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2421
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2503
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4226258440
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)