Planaria EST Database


DrC_02646

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02646
         (205 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P16333|NCK1_HUMAN  Cytoplasmic protein NCK1 (NCK adaptor ...    65   5e-11
sp|O43639|NCK2_HUMAN  Cytoplasmic protein NCK2 (NCK adaptor ...    62   3e-10
sp|P08630|BTKL_DROME  Tyrosine-protein kinase Btk29A (Dsrc28C)     54   1e-07
sp|Q08509|EPS8_MOUSE  Epidermal growth factor receptor kinas...    53   2e-07
sp|Q12929|EPS8_HUMAN  Epidermal growth factor receptor kinas...    52   4e-07
sp|Q5R4H4|EPS8_PONPY  Epidermal growth factor receptor kinas...    52   4e-07
sp|Q08881|ITK_HUMAN  Tyrosine-protein kinase ITK/TSK (T-cell...    50   1e-06
sp|P24604|TEC_MOUSE  Tyrosine-protein kinase Tec                   50   2e-06
sp|P42680|TEC_HUMAN  Tyrosine-protein kinase Tec                   49   4e-06
sp|P06241|FYN_HUMAN  Proto-oncogene tyrosine-protein kinase ...    49   5e-06
>sp|P16333|NCK1_HUMAN Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor
           protein NCK-alpha)
          Length = 377

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 29/50 (58%), Positives = 37/50 (74%)
 Frame = +2

Query: 53  MAVAKFDYKAVDLHELNINKGEKLTLVDDSQHWWQVMNSKGETGYVPSNY 202
           + VAKFDY A    EL+I K E+L L+DDS+ WW+V NS  +TG+VPSNY
Sbjct: 6   VVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNY 55

 Score = 33.9 bits (76), Expect = 0.12
 Identities = 15/57 (26%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
 Frame = +2

Query: 41  QPVGMAVAKFDYKAVDLHELNINKGEKLTLVDDSQH---WWQVMNSKGETGYVPSNY 202
           Q + +  A + + + +  ELN  KG+ + +++  ++   WW+     G  G VP NY
Sbjct: 190 QVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNY 246
>sp|O43639|NCK2_HUMAN Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor
           protein NCK-beta) (Nck-2)
          Length = 380

 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 27/50 (54%), Positives = 36/50 (72%)
 Frame = +2

Query: 53  MAVAKFDYKAVDLHELNINKGEKLTLVDDSQHWWQVMNSKGETGYVPSNY 202
           + +AK+DY A    EL+I K E+L L+DDS+ WW+V N+   TGYVPSNY
Sbjct: 6   IVIAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNY 55

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 16/48 (33%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
 Frame = +2

Query: 68  FDYKAVDLHELNINKGEKLTLVDDSQH---WWQVMNSKGETGYVPSNY 202
           + + +V   ELN  KGE + +++  ++   WW+  N++G+ G VP NY
Sbjct: 204 YPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNY 251
>sp|P08630|BTKL_DROME Tyrosine-protein kinase Btk29A (Dsrc28C)
          Length = 786

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 22/53 (41%), Positives = 37/53 (69%), Gaps = 1/53 (1%)
 Frame = +2

Query: 47  VGMAVAKFDYKAVDLHELNINKGEKLTLVDDSQ-HWWQVMNSKGETGYVPSNY 202
           V + VA + +KA++  +L++ K  +  ++DDSQ HWW+V ++ G  GY+PSNY
Sbjct: 344 VKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNY 396
>sp|Q08509|EPS8_MOUSE Epidermal growth factor receptor kinase substrate 8
          Length = 821

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 21/53 (39%), Positives = 37/53 (69%)
 Frame = +2

Query: 41  QPVGMAVAKFDYKAVDLHELNINKGEKLTLVDDSQHWWQVMNSKGETGYVPSN 199
           QP   A +K+D+ A +  EL++ K + L ++DD + WW+V N+ G++G+VP+N
Sbjct: 530 QPKKYAKSKYDFVARNSSELSVMKDDVLEILDDRRQWWKVRNASGDSGFVPNN 582
>sp|Q12929|EPS8_HUMAN Epidermal growth factor receptor kinase substrate 8
          Length = 822

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 21/53 (39%), Positives = 37/53 (69%)
 Frame = +2

Query: 41  QPVGMAVAKFDYKAVDLHELNINKGEKLTLVDDSQHWWQVMNSKGETGYVPSN 199
           QP   A +K+D+ A +  EL++ K + L ++DD + WW+V N+ G++G+VP+N
Sbjct: 531 QPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNN 583
>sp|Q5R4H4|EPS8_PONPY Epidermal growth factor receptor kinase substrate 8
          Length = 822

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 21/53 (39%), Positives = 37/53 (69%)
 Frame = +2

Query: 41  QPVGMAVAKFDYKAVDLHELNINKGEKLTLVDDSQHWWQVMNSKGETGYVPSN 199
           QP   A +K+D+ A +  EL++ K + L ++DD + WW+V N+ G++G+VP+N
Sbjct: 531 QPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNN 583
>sp|Q08881|ITK_HUMAN Tyrosine-protein kinase ITK/TSK (T-cell-specific kinase)
           (Tyrosine-protein kinase Lyk) (Kinase EMT)
          Length = 620

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 21/51 (41%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
 Frame = +2

Query: 53  MAVAKFDYKAVDLHELNINKGEKLTLVDDSQ-HWWQVMNSKGETGYVPSNY 202
           + +A +DY+  D  EL + + E+  L+D S+ HWW+V +  G  GYVPS+Y
Sbjct: 175 VVIALYDYQTNDPQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGYVPSSY 225
>sp|P24604|TEC_MOUSE Tyrosine-protein kinase Tec
          Length = 630

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 17/51 (33%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
 Frame = +2

Query: 53  MAVAKFDYKAVDLHELNINKGEKLTLVDDSQ-HWWQVMNSKGETGYVPSNY 202
           + VA +D++A + H+L + +G++  +++ +  HWW+  +  G  GY+PSNY
Sbjct: 182 IVVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGSEGYIPSNY 232
>sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec
          Length = 631

 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 17/51 (33%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
 Frame = +2

Query: 53  MAVAKFDYKAVDLHELNINKGEKLTLVDDSQ-HWWQVMNSKGETGYVPSNY 202
           + VA +D++A + H+L + +G++  +++ +  HWW+  +  G  GY+PSNY
Sbjct: 183 IVVAMYDFQAAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNY 233
>sp|P06241|FYN_HUMAN Proto-oncogene tyrosine-protein kinase Fyn (p59-Fyn) (Protooncogene
           Syn) (SLK)
          Length = 537

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 23/54 (42%), Positives = 37/54 (68%), Gaps = 2/54 (3%)
 Frame = +2

Query: 47  VGMAVAKFDYKAVDLHELNINKGEKLTLVDDSQ-HWWQVMN-SKGETGYVPSNY 202
           V + VA +DY+A    +L+ +KGEK  +++ S+  WW+  + + GETGY+PSNY
Sbjct: 84  VTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNY 137
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,562,997
Number of Sequences: 369166
Number of extensions: 376954
Number of successful extensions: 1290
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1191
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1230
length of database: 68,354,980
effective HSP length: 39
effective length of database: 61,150,315
effective search space used: 1712208820
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)