Planaria EST Database


DrC_02644

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02644
         (846 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9Z2S9|FLOT2_RAT  Flotillin-2 (Reggie-1) (REG-1)               333   4e-91
sp|O61492|FLOT2_DROME  Flotillin-2                                332   1e-90
sp|Q98TZ8|FLT2_BRARE  Flotillin-2a (Reggie-1a) (REG-1)            331   2e-90
sp|O42305|FLOT2_CARAU  Flotillin-2 (Reggie-1) (REG-1)             327   3e-89
sp|Q60634|FLOT2_MOUSE  Flotillin-2 (Epidermal surface antige...   271   2e-72
sp|Q14254|FLOT2_HUMAN  Flotillin-2 (Epidermal surface antige...   271   2e-72
sp|O61491|FLOT1_DROME  Flotillin-1                                214   2e-55
sp|O75955|FLOT1_HUMAN  Flotillin-1                                207   2e-53
sp|Q7YR41|FLOT1_PANTR  Flotillin-1                                207   2e-53
sp|O08917|FLOT1_MOUSE  Flotillin-1                                204   2e-52
>sp|Q9Z2S9|FLOT2_RAT Flotillin-2 (Reggie-1) (REG-1)
          Length = 428

 Score =  333 bits (854), Expect = 4e-91
 Identities = 164/250 (65%), Positives = 195/250 (78%)
 Frame = +3

Query: 3   PNEALAISGGCCGTGSMKTIIGGWGWAWWLVSQVQKISLEVMTLNPTCEHVETKEGVPLT 182
           PNEAL +SGGCCG+   + + GGW WAWW +S  Q+ISLE+MTL P CE VET EGV LT
Sbjct: 9   PNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVETAEGVALT 68

Query: 183 VTGVAQVKVMTEPSLLATACEQFLGRRRSEIEETILQTLDGHLRAILGTLTVEAIYQDRD 362
           VTGVAQVK+MTE  LLA ACEQFLG+   +I+  +LQTL+GHLR+ILGTLTVE IYQDRD
Sbjct: 69  VTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRD 128

Query: 363 QFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGRAQTAIVKRDADIGVAEAER 542
           QFA  VREVAAPDV +MGIEILSFTIKDVYDKV+YL+SLG+ QTA+V+RDADIGVAEAER
Sbjct: 129 QFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAER 188

Query: 543 DAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAEVFKVRXXXXXXXXXXXXXX 722
           DAGIREAEC+K  +DV++ ADT+IA++ R F+LQK++F  EV                  
Sbjct: 189 DAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGARE 248

Query: 723 XQKIRSEEIQ 752
            QKIR EEI+
Sbjct: 249 QQKIRQEEIE 258
>sp|O61492|FLOT2_DROME Flotillin-2
          Length = 438

 Score =  332 bits (850), Expect = 1e-90
 Identities = 168/263 (63%), Positives = 199/263 (75%), Gaps = 13/263 (4%)
 Frame = +3

Query: 3   PNEALAISGGCCGTGSMKTIIGGWGWAWWLVSQVQKISLEVMTLNPTCEHVETKEGVPLT 182
           PNEAL +SGGCCG+   +TI+GGW WAWWLV+ VQ++SL VMTLNP CE+VET +GVPLT
Sbjct: 9   PNEALIVSGGCCGSTKKRTIVGGWAWAWWLVTDVQRLSLNVMTLNPMCENVETSQGVPLT 68

Query: 183 VTGVAQVKVMTEPS-------------LLATACEQFLGRRRSEIEETILQTLDGHLRAIL 323
           VTGVAQ K+M   S             LL TA EQFLG+   EI++TILQTL+GHLRAIL
Sbjct: 69  VTGVAQCKIMKSSSYKQTDYHNDEADELLGTASEQFLGKSVKEIKQTILQTLEGHLRAIL 128

Query: 324 GTLTVEAIYQDRDQFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGRAQTAIV 503
           GTLTVE +Y+DRDQFA  VREVAAPDV +MGIEILSFTIKDVYD V+YL SLG+AQTA+V
Sbjct: 129 GTLTVEEVYKDRDQFAALVREVAAPDVGRMGIEILSFTIKDVYDDVQYLASLGKAQTAVV 188

Query: 504 KRDADIGVAEAERDAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAEVFKVRX 683
           KRDAD GVAEA RDAGIREAECEK+ MDV+Y  DT+I + TR ++LQKA+FD E+   + 
Sbjct: 189 KRDADAGVAEANRDAGIREAECEKSAMDVKYSTDTKIEDNTRMYKLQKANFDQEINTAKA 248

Query: 684 XXXXXXXXXXXXXXQKIRSEEIQ 752
                         Q+IR+EEIQ
Sbjct: 249 ESQLAYELQAAKIRQRIRNEEIQ 271
>sp|Q98TZ8|FLT2_BRARE Flotillin-2a (Reggie-1a) (REG-1)
          Length = 428

 Score =  331 bits (848), Expect = 2e-90
 Identities = 162/250 (64%), Positives = 198/250 (79%)
 Frame = +3

Query: 3   PNEALAISGGCCGTGSMKTIIGGWGWAWWLVSQVQKISLEVMTLNPTCEHVETKEGVPLT 182
           PNEAL +SGGCCG+      +GGW WAWWL++ +QKI+LE+MTL P CE VET EGV +T
Sbjct: 9   PNEALVVSGGCCGSDGKTYTVGGWAWAWWLITDIQKITLEIMTLQPKCEDVETAEGVAIT 68

Query: 183 VTGVAQVKVMTEPSLLATACEQFLGRRRSEIEETILQTLDGHLRAILGTLTVEAIYQDRD 362
           VTGVAQVKVMT+  LL  ACEQFLG+  +EI+  ILQTL+GHLR+ILGTLTVE IYQDRD
Sbjct: 69  VTGVAQVKVMTDNELLGYACEQFLGKTVTEIKSVILQTLEGHLRSILGTLTVEQIYQDRD 128

Query: 363 QFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGRAQTAIVKRDADIGVAEAER 542
           QFA  VREVAAPDV +MGIEILSFTIKDVYDKV+YL+SLG++QTA V+RDADIGVAEAER
Sbjct: 129 QFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKSQTAAVQRDADIGVAEAER 188

Query: 543 DAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAEVFKVRXXXXXXXXXXXXXX 722
           DAGIREAEC+K  MD++++ADT++A++ R  ++QKA+F+ EV   +              
Sbjct: 189 DAGIREAECKKEMMDIKFQADTKMADSKRELEMQKAAFNQEVNTKKAEAQLAYELQAAKE 248

Query: 723 XQKIRSEEIQ 752
            QKIR EEI+
Sbjct: 249 QQKIRLEEIE 258
>sp|O42305|FLOT2_CARAU Flotillin-2 (Reggie-1) (REG-1)
          Length = 428

 Score =  327 bits (838), Expect = 3e-89
 Identities = 161/250 (64%), Positives = 195/250 (78%)
 Frame = +3

Query: 3   PNEALAISGGCCGTGSMKTIIGGWGWAWWLVSQVQKISLEVMTLNPTCEHVETKEGVPLT 182
           PNEAL +SG CCG+ +   ++GGW WAWWL+S  Q+I+LE+MTL P CE VET EGV +T
Sbjct: 9   PNEALVVSGACCGSDAKTYVVGGWAWAWWLISDTQRITLEIMTLQPKCEDVETAEGVAIT 68

Query: 183 VTGVAQVKVMTEPSLLATACEQFLGRRRSEIEETILQTLDGHLRAILGTLTVEAIYQDRD 362
           VTGVAQVKVMT+  LLA ACEQFLG+   EI+  +LQTL+GHLR+ILGTLTVE IYQDRD
Sbjct: 69  VTGVAQVKVMTDQDLLAVACEQFLGKSVMEIKAVVLQTLEGHLRSILGTLTVEQIYQDRD 128

Query: 363 QFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGRAQTAIVKRDADIGVAEAER 542
           +FA  VREVAAPDV +MGIEILSFTIKDVYDK++YL+SLG+ QTA V+RDADIGVAEAER
Sbjct: 129 EFARLVREVAAPDVGRMGIEILSFTIKDVYDKLDYLSSLGKTQTAAVQRDADIGVAEAER 188

Query: 543 DAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAEVFKVRXXXXXXXXXXXXXX 722
           DAGIREAEC+K  MDV++ ADT +A++ R  +LQKA+F+ EV   +              
Sbjct: 189 DAGIREAECKKEMMDVKFLADTRMADSKRELELQKAAFNQEVNTKKAESQLAYELEAAKE 248

Query: 723 XQKIRSEEIQ 752
            QKIR EEI+
Sbjct: 249 QQKIRLEEIE 258
>sp|Q60634|FLOT2_MOUSE Flotillin-2 (Epidermal surface antigen) (ESA)
          Length = 379

 Score =  271 bits (693), Expect = 2e-72
 Identities = 140/209 (66%), Positives = 164/209 (78%)
 Frame = +3

Query: 126 MTLNPTCEHVETKEGVPLTVTGVAQVKVMTEPSLLATACEQFLGRRRSEIEETILQTLDG 305
           MTL P CE VET EGV LTVTGVAQVK+MTE  LLA ACEQFLG+   +I+  +LQTL+G
Sbjct: 1   MTLQPRCEDVETAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEG 60

Query: 306 HLRAILGTLTVEAIYQDRDQFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGR 485
           HLR+ILGTLTVE IYQDRDQFA  VREVAAPDV +MGIEILSFTIKDVYDKV+YL+SLG+
Sbjct: 61  HLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGK 120

Query: 486 AQTAIVKRDADIGVAEAERDAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAE 665
            QTA+V+RDADIGVAEAERDAGIREAEC+K  +DV++ ADT+IA++ R F+LQK++F  E
Sbjct: 121 TQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEE 180

Query: 666 VFKVRXXXXXXXXXXXXXXXQKIRSEEIQ 752
           V                   QKIR EEI+
Sbjct: 181 VNIKTAEAQLAYELQGAREQQKIRQEEIE 209
>sp|Q14254|FLOT2_HUMAN Flotillin-2 (Epidermal surface antigen) (ESA)
          Length = 379

 Score =  271 bits (693), Expect = 2e-72
 Identities = 140/209 (66%), Positives = 164/209 (78%)
 Frame = +3

Query: 126 MTLNPTCEHVETKEGVPLTVTGVAQVKVMTEPSLLATACEQFLGRRRSEIEETILQTLDG 305
           MTL P CE VET EGV LTVTGVAQVK+MTE  LLA ACEQFLG+   +I+  +LQTL+G
Sbjct: 1   MTLQPRCEDVETAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEG 60

Query: 306 HLRAILGTLTVEAIYQDRDQFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGR 485
           HLR+ILGTLTVE IYQDRDQFA  VREVAAPDV +MGIEILSFTIKDVYDKV+YL+SLG+
Sbjct: 61  HLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGK 120

Query: 486 AQTAIVKRDADIGVAEAERDAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAE 665
            QTA+V+RDADIGVAEAERDAGIREAEC+K  +DV++ ADT+IA++ R F+LQK++F  E
Sbjct: 121 TQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEE 180

Query: 666 VFKVRXXXXXXXXXXXXXXXQKIRSEEIQ 752
           V                   QKIR EEI+
Sbjct: 181 VNIKTAEAQLAYELQGAREQQKIRQEEIE 209
>sp|O61491|FLOT1_DROME Flotillin-1
          Length = 426

 Score =  214 bits (545), Expect = 2e-55
 Identities = 123/253 (48%), Positives = 166/253 (65%), Gaps = 3/253 (1%)
 Frame = +3

Query: 3   PNEALAISGGCCGTGSMKTII--GGWGWAWWLVSQVQKISLEVMTLNPTCEHVETKEGVP 176
           PNEAL +SG CC    MK ++  GG  + W +  QVQ+ISL  MTL      V T +GVP
Sbjct: 10  PNEALVVSG-CC---YMKPLLVPGGRAFVWPVGQQVQRISLNTMTLQVESPCVYTSQGVP 65

Query: 177 LTVTGVAQVKVMTE-PSLLATACEQFLGRRRSEIEETILQTLDGHLRAILGTLTVEAIYQ 353
           ++VTG+AQVKV  +   +L TACEQFLG+  +EI    L TL+GH RAI+G++TVE IY+
Sbjct: 66  ISVTGIAQVKVQGQNEDMLLTACEQFLGKSEAEINHIALVTLEGHQRAIMGSMTVEEIYK 125

Query: 354 DRDQFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGRAQTAIVKRDADIGVAE 533
           DR +F+ QV EVA+ D+A MGI ++S+TIKD+ D+  YL SLG A+TA VKRDA IG AE
Sbjct: 126 DRKKFSKQVFEVASSDLANMGITVVSYTIKDLRDEEGYLRSLGMARTAEVKRDARIGEAE 185

Query: 534 AERDAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAEVFKVRXXXXXXXXXXX 713
           A  +A I+EA  E+ RM  R+  DT+IA A R F+L+KA++D EV   +           
Sbjct: 186 ARAEAHIKEAIAEEQRMAARFLNDTDIAKAQRDFELKKAAYDVEVQTKKAEAEMAYELQA 245

Query: 714 XXXXQKIRSEEIQ 752
               Q+I+ E++Q
Sbjct: 246 AKTKQRIKEEQMQ 258
>sp|O75955|FLOT1_HUMAN Flotillin-1
          Length = 427

 Score =  207 bits (528), Expect = 2e-53
 Identities = 108/251 (43%), Positives = 166/251 (66%), Gaps = 1/251 (0%)
 Frame = +3

Query: 3   PNEALAISGGCCGTGSMKTIIGGWGWAWWLVSQVQKISLEVMTLNPTCEHVETKEGVPLT 182
           PNEA+ +SG C     M  + GG  +    + Q+Q+ISL  +TLN   E V T+ GVP++
Sbjct: 7   PNEAMVVSGFCRSPPVM--VAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPIS 64

Query: 183 VTGVAQVKVMTE-PSLLATACEQFLGRRRSEIEETILQTLDGHLRAILGTLTVEAIYQDR 359
           VTG+AQVK+  +   +LA AC+ FLG+  +EI    L+TL+GH RAI+  +TVE IY+DR
Sbjct: 65  VTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDR 124

Query: 360 DQFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGRAQTAIVKRDADIGVAEAE 539
            +F+ QV +VA+ D+  MGI ++S+T+KD++D  +YL+SLG+A+TA V++DA IG AEA+
Sbjct: 125 QKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAK 184

Query: 540 RDAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAEVFKVRXXXXXXXXXXXXX 719
           RDAGIREA+ ++ ++  +Y ++ E+A A R ++L+KA++D EV   R             
Sbjct: 185 RDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAK 244

Query: 720 XXQKIRSEEIQ 752
             Q+I  + +Q
Sbjct: 245 TKQQIEEQRVQ 255
>sp|Q7YR41|FLOT1_PANTR Flotillin-1
          Length = 427

 Score =  207 bits (528), Expect = 2e-53
 Identities = 108/251 (43%), Positives = 166/251 (66%), Gaps = 1/251 (0%)
 Frame = +3

Query: 3   PNEALAISGGCCGTGSMKTIIGGWGWAWWLVSQVQKISLEVMTLNPTCEHVETKEGVPLT 182
           PNEA+ +SG C     M  + GG  +    + Q+Q+ISL  +TLN   E V T+ GVP++
Sbjct: 7   PNEAMVVSGFCRSPPVM--VAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPIS 64

Query: 183 VTGVAQVKVMTE-PSLLATACEQFLGRRRSEIEETILQTLDGHLRAILGTLTVEAIYQDR 359
           VTG+AQVK+  +   +LA AC+ FLG+  +EI    L+TL+GH RAI+  +TVE IY+DR
Sbjct: 65  VTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDR 124

Query: 360 DQFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGRAQTAIVKRDADIGVAEAE 539
            +F+ QV +VA+ D+  MGI ++S+T+KD++D  +YL+SLG+A+TA V++DA IG AEA+
Sbjct: 125 QKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAK 184

Query: 540 RDAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAEVFKVRXXXXXXXXXXXXX 719
           RDAGIREA+ ++ ++  +Y ++ E+A A R ++L+KA++D EV   R             
Sbjct: 185 RDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAK 244

Query: 720 XXQKIRSEEIQ 752
             Q+I  + +Q
Sbjct: 245 TKQQIEEQRVQ 255
>sp|O08917|FLOT1_MOUSE Flotillin-1
          Length = 428

 Score =  204 bits (519), Expect = 2e-52
 Identities = 107/251 (42%), Positives = 165/251 (65%), Gaps = 1/251 (0%)
 Frame = +3

Query: 3   PNEALAISGGCCGTGSMKTIIGGWGWAWWLVSQVQKISLEVMTLNPTCEHVETKEGVPLT 182
           PNEA+ +SG C     M  + GG  +    + Q+Q+ISL  +TLN   E V T+ GVP++
Sbjct: 7   PNEAMVVSGFCRSPPVM--VAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPIS 64

Query: 183 VTGVAQVKVMTE-PSLLATACEQFLGRRRSEIEETILQTLDGHLRAILGTLTVEAIYQDR 359
           VTG+AQVK+  +   +LA AC+ FLG+  +EI    L+TL+GH RAI+  +TVE IY+DR
Sbjct: 65  VTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDR 124

Query: 360 DQFAHQVREVAAPDVAKMGIEILSFTIKDVYDKVEYLNSLGRAQTAIVKRDADIGVAEAE 539
            +F+ QV +VA+ D+  MGI ++S+T+KD++D  +YL+SLG+A+TA V++DA IG AEA+
Sbjct: 125 QKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAK 184

Query: 540 RDAGIREAECEKARMDVRYEADTEIANATRGFQLQKASFDAEVFKVRXXXXXXXXXXXXX 719
           RDAGIREA+ ++ ++  +  ++ E+A A R ++L+KA++D EV   R             
Sbjct: 185 RDAGIREAKAKQEKVSAQCLSEIEMAKAQRDYELKKATYDIEVNTRRAQADLAYQLQVAK 244

Query: 720 XXQKIRSEEIQ 752
             Q+I  + +Q
Sbjct: 245 TKQQIEEQRVQ 255
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,711,460
Number of Sequences: 369166
Number of extensions: 1530023
Number of successful extensions: 5284
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4989
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5259
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)