Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02641 (602 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P28741|KIF3A_MOUSE Kinesin-like protein KIF3A (Microtubu... 142 5e-34 sp|P46867|KLP68_DROME Kinesin-like protein KLP68D 142 5e-34 sp|Q9Y496|KIF3A_HUMAN Kinesin-like protein KIF3A (Microtubu... 142 5e-34 sp|P46872|KRP85_STRPU Kinesin-II 85 kDa subunit (KRP-85/95 ... 140 3e-33 sp|O15066|KIF3B_HUMAN Kinesin-like protein KIF3B (Microtubu... 139 6e-33 sp|Q61771|KIF3B_MOUSE Kinesin-like protein KIF3B (Microtubu... 139 6e-33 sp|P46873|OSM3_CAEEL Osmotic avoidance abnormal protein 3 (... 138 9e-33 sp|P46871|KRP95_STRPU Kinesin-II 95 kDa subunit (KRP-85/95 ... 138 1e-32 sp|P33176|KINH_HUMAN Kinesin heavy chain (Ubiquitous kinesi... 135 1e-31 sp|Q61768|KINH_MOUSE Kinesin heavy chain (Ubiquitous kinesi... 135 1e-31
>sp|P28741|KIF3A_MOUSE Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A) Length = 701 Score = 142 bits (359), Expect = 5e-34 Identities = 79/165 (47%), Positives = 111/165 (67%), Gaps = 6/165 (3%) Frame = +3 Query: 6 VASTKMNAESSRSHLIISIMLTCHLKNSE---NIIRGKISIIDLAGSERVSKSGVQGVGA 176 V +T MN SSRSH I +I + C K + ++ GK+ ++DLAGSER +K+G G Sbjct: 208 VGATNMNEHSSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRL 267 Query: 177 QEAMCINLSLSALGDVISALTSGQQ-FIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEY 353 +EA INLSLS LG+VISAL G+ +PYRN+KLT L+QDS+GGN+KT+M ++ P +Y Sbjct: 268 KEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADY 327 Query: 354 NYVETINSLTYGARVKLIKNESTKSFDSEEA--PRLMKIIEHLKR 482 NY ETI++L Y R K IKN++ + D ++A + K IE LK+ Sbjct: 328 NYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKK 372
>sp|P46867|KLP68_DROME Kinesin-like protein KLP68D Length = 784 Score = 142 bits (359), Expect = 5e-34 Identities = 77/161 (47%), Positives = 106/161 (65%), Gaps = 2/161 (1%) Frame = +3 Query: 6 VASTKMNAESSRSHLIISIMLTCHLKNSENIIRGKISIIDLAGSERVSKSGVQGVGAQEA 185 V T MN SSRSH I I + + I GK+++IDLAGSER SK+G +EA Sbjct: 211 VGFTNMNEHSSRSHAIFMIKIEMCDTETNTIKVGKLNLIDLAGSERQSKTGASAERLKEA 270 Query: 186 MCINLSLSALGDVISALTSGQQFIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEYNYVE 365 INL+LS+LG+VISAL +PYR++KLT L+QDS+GGN+KT+MI ++ P+ YNY E Sbjct: 271 SKINLALSSLGNVISALAESSPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNE 330 Query: 366 TINSLTYGARVKLIKNESTKSFDSEEA--PRLMKIIEHLKR 482 T+ +L YG+R K I+N+ K+ D ++A + IE LKR Sbjct: 331 TLTTLRYGSRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKR 371
>sp|Q9Y496|KIF3A_HUMAN Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A) Length = 702 Score = 142 bits (359), Expect = 5e-34 Identities = 79/165 (47%), Positives = 111/165 (67%), Gaps = 6/165 (3%) Frame = +3 Query: 6 VASTKMNAESSRSHLIISIMLTCHLKNSE---NIIRGKISIIDLAGSERVSKSGVQGVGA 176 V +T MN SSRSH I +I + C K + ++ GK+ ++DLAGSER +K+G G Sbjct: 208 VGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRL 267 Query: 177 QEAMCINLSLSALGDVISALTSGQQ-FIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEY 353 +EA INLSLS LG+VISAL G+ +PYRN+KLT L+QDS+GGN+KT+M ++ P +Y Sbjct: 268 KEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADY 327 Query: 354 NYVETINSLTYGARVKLIKNESTKSFDSEEA--PRLMKIIEHLKR 482 NY ETI++L Y R K IKN++ + D ++A + K IE LK+ Sbjct: 328 NYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKK 372
>sp|P46872|KRP85_STRPU Kinesin-II 85 kDa subunit (KRP-85/95 85 kDa subunit) Length = 699 Score = 140 bits (352), Expect = 3e-33 Identities = 81/165 (49%), Positives = 109/165 (66%), Gaps = 6/165 (3%) Frame = +3 Query: 6 VASTKMNAESSRSHLIISIMLT---CHLKNSENIIRGKISIIDLAGSERVSKSGVQGVGA 176 V +T MN SSRSH I +I L L +++ GK+ ++DLAGSER +K+G G Sbjct: 205 VGATNMNESSSRSHAIFTITLERSDMGLDKEQHVRVGKLHMVDLAGSERQTKTGATGQRL 264 Query: 177 QEAMCINLSLSALGDVISALTSGQQ-FIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEY 353 +EA INLSLS LG+VIS+L G+ IPYRN+KLT L+QDS+GGNAKT+M ++ P EY Sbjct: 265 KEATKINLSLSTLGNVISSLVDGKSTHIPYRNSKLTRLLQDSLGGNAKTVMCANIGPAEY 324 Query: 354 NYVETINSLTYGARVKLIKNESTKSFDSEEA--PRLMKIIEHLKR 482 NY ETI++L Y R K IKN++ + D ++A K IE LK+ Sbjct: 325 NYDETISTLRYANRAKNIKNKAKINEDPKDALLREFQKEIEELKK 369
>sp|O15066|KIF3B_HUMAN Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048) Length = 747 Score = 139 bits (350), Expect = 6e-33 Identities = 79/151 (52%), Positives = 104/151 (68%), Gaps = 4/151 (2%) Frame = +3 Query: 6 VASTKMNAESSRSHLIISIMLTCHLK--NSENIIR-GKISIIDLAGSERVSKSGVQGVGA 176 V +T MN SSRSH I I + C + EN IR GK++++DLAGSER +K+G QG Sbjct: 203 VGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERL 262 Query: 177 QEAMCINLSLSALGDVISALTSGQQ-FIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEY 353 +EA INLSLSALG+VISAL G+ IPYR++KLT L+QDS+GGNAKT+M+ +V P Y Sbjct: 263 KEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASY 322 Query: 354 NYVETINSLTYGARVKLIKNESTKSFDSEEA 446 N ET+ +L Y R K IKN+ + D ++A Sbjct: 323 NVEETLTTLRYANRAKNIKNKPRVNEDPKDA 353
>sp|Q61771|KIF3B_MOUSE Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) Length = 747 Score = 139 bits (350), Expect = 6e-33 Identities = 79/151 (52%), Positives = 104/151 (68%), Gaps = 4/151 (2%) Frame = +3 Query: 6 VASTKMNAESSRSHLIISIMLTCHLK--NSENIIR-GKISIIDLAGSERVSKSGVQGVGA 176 V +T MN SSRSH I I + C + EN IR GK++++DLAGSER +K+G QG Sbjct: 203 VGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERL 262 Query: 177 QEAMCINLSLSALGDVISALTSGQQ-FIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEY 353 +EA INLSLSALG+VISAL G+ IPYR++KLT L+QDS+GGNAKT+M+ +V P Y Sbjct: 263 KEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASY 322 Query: 354 NYVETINSLTYGARVKLIKNESTKSFDSEEA 446 N ET+ +L Y R K IKN+ + D ++A Sbjct: 323 NVEETLTTLRYANRAKNIKNKPRVNEDPKDA 353
>sp|P46873|OSM3_CAEEL Osmotic avoidance abnormal protein 3 (Kinesin-like protein osm-3) Length = 699 Score = 138 bits (348), Expect = 9e-33 Identities = 77/149 (51%), Positives = 107/149 (71%), Gaps = 1/149 (0%) Frame = +3 Query: 3 HVASTKMNAESSRSHLIISIMLTCHLKNSENIIRGKISIIDLAGSERVSKSGVQGVGAQE 182 HV +T MN +SSRSH I ++ + + + +I GK++++DLAGSER SK+G G +E Sbjct: 193 HVGATLMNKDSSRSHSIFTVYVE-GMTETGSIRMGKLNLVDLAGSERQSKTGATGDRLKE 251 Query: 183 AMCINLSLSALGDVISALTSGQ-QFIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEYNY 359 A INLSLSALG+VISAL G+ + IPYR++KLT L+QDS+GGN KT+MI VSP+ NY Sbjct: 252 ATKINLSLSALGNVISALVDGKSKHIPYRDSKLTRLLQDSLGGNTKTIMIACVSPSSDNY 311 Query: 360 VETINSLTYGARVKLIKNESTKSFDSEEA 446 ET+++L Y R K IKN+ T + D ++A Sbjct: 312 DETLSTLRYANRAKNIKNKPTINEDPKDA 340
>sp|P46871|KRP95_STRPU Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa subunit) Length = 742 Score = 138 bits (347), Expect = 1e-32 Identities = 79/151 (52%), Positives = 104/151 (68%), Gaps = 4/151 (2%) Frame = +3 Query: 6 VASTKMNAESSRSHLIISIMLTCHLK--NSENIIR-GKISIIDLAGSERVSKSGVQGVGA 176 V ST MN SSRSH I I + C + EN IR GK++++DLAGSER +K+G G Sbjct: 202 VGSTNMNEHSSRSHAIFIITIECSELGVDGENHIRVGKLNLVDLAGSERQAKTGATGDRL 261 Query: 177 QEAMCINLSLSALGDVISALTSGQQ-FIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEY 353 +EA INLSLSALG+VISAL G+ IPYR++KLT L+QDS+GGNAKT+M+ ++ P Y Sbjct: 262 KEATKINLSLSALGNVISALVDGKSSHIPYRDSKLTRLLQDSLGGNAKTVMVANMGPASY 321 Query: 354 NYVETINSLTYGARVKLIKNESTKSFDSEEA 446 N+ ETI +L Y R K IKN+ + D ++A Sbjct: 322 NFDETITTLRYANRAKNIKNKPKINEDPKDA 352
>sp|P33176|KINH_HUMAN Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC) Length = 963 Score = 135 bits (339), Expect = 1e-31 Identities = 68/137 (49%), Positives = 94/137 (68%) Frame = +3 Query: 3 HVASTKMNAESSRSHLIISIMLTCHLKNSENIIRGKISIIDLAGSERVSKSGVQGVGAQE 182 HVA T MN SSRSH I I + +E + GK+ ++DLAGSE+VSK+G +G E Sbjct: 191 HVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDE 250 Query: 183 AMCINLSLSALGDVISALTSGQQFIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEYNYV 362 A IN SLSALG+VISAL G ++PYR++K+T ++QDS+GGN +T +++ SP+ YN Sbjct: 251 AKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNES 310 Query: 363 ETINSLTYGARVKLIKN 413 ET ++L +G R K IKN Sbjct: 311 ETKSTLLFGQRAKTIKN 327
>sp|Q61768|KINH_MOUSE Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC) Length = 963 Score = 135 bits (339), Expect = 1e-31 Identities = 68/137 (49%), Positives = 94/137 (68%) Frame = +3 Query: 3 HVASTKMNAESSRSHLIISIMLTCHLKNSENIIRGKISIIDLAGSERVSKSGVQGVGAQE 182 HVA T MN SSRSH I I + +E + GK+ ++DLAGSE+VSK+G +G E Sbjct: 191 HVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDE 250 Query: 183 AMCINLSLSALGDVISALTSGQQFIPYRNNKLTLLMQDSIGGNAKTLMIVHVSPTEYNYV 362 A IN SLSALG+VISAL G ++PYR++K+T ++QDS+GGN +T +++ SP+ YN Sbjct: 251 AKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNES 310 Query: 363 ETINSLTYGARVKLIKN 413 ET ++L +G R K IKN Sbjct: 311 ETKSTLLFGQRAKTIKN 327
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 59,342,066 Number of Sequences: 369166 Number of extensions: 1074432 Number of successful extensions: 2685 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2490 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2551 length of database: 68,354,980 effective HSP length: 105 effective length of database: 48,957,805 effective search space used: 4650991475 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)