Planaria EST Database


DrC_02637

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02637
         (914 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P70191|TRAF5_MOUSE  TNF receptor-associated factor 5            86   2e-16
sp|P39429|TRAF2_MOUSE  TNF receptor-associated factor 2            84   6e-16
sp|O00463|TRAF5_HUMAN  TNF receptor-associated factor 5 (RIN...    84   6e-16
sp|Q12933|TRAF2_HUMAN  TNF receptor-associated factor 2 (Tum...    84   7e-16
sp|Q13114|TRAF3_HUMAN  TNF receptor-associated factor 3 (CD4...    82   2e-15
sp|Q60803|TRAF3_MOUSE  TNF receptor-associated factor 3 (CD4...    82   2e-15
sp|P39428|TRAF1_MOUSE  TNF receptor-associated factor 1            82   3e-15
sp|Q13077|TRAF1_HUMAN  TNF receptor-associated factor 1 (Eps...    80   6e-15
sp|Q9BUZ4|TRAF4_HUMAN  TNF receptor-associated factor 4 (Cys...    73   1e-12
sp|Q61382|TRAF4_MOUSE  TNF receptor-associated factor 4 (Cys...    72   3e-12
>sp|P70191|TRAF5_MOUSE TNF receptor-associated factor 5
          Length = 558

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 38/92 (41%), Positives = 55/92 (59%)
 Frame = +3

Query: 639 GEFIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRVDPDGDGSAKGTHLSLYY 818
           G+ IW+             G    ++S  FYT + GY++C R   +GDGS KGTHLSLY+
Sbjct: 404 GKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYF 463

Query: 819 CLMKGEFDDILEWSFKFDLTLSLIDQQTRLAH 914
            +M+GEFD +L+W F+  +TL L+DQ  +  H
Sbjct: 464 VVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNH 495

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 30/87 (34%), Positives = 48/87 (55%)
 Frame = +3

Query: 135 NGEFVWIIDKISEKMKDAKNGINTTIYSDSFYTHKNGYKMCLSAEPDGFDEDKGNLCFVL 314
           +G+ +W +     K ++A  G   +++S  FYT + GY++C  A  +G    KG    + 
Sbjct: 403 SGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLY 462

Query: 315 FHLMKGEFDDDLMWPFAFDVTFSLINQ 395
           F +M+GEFD  L WPF   VT  L++Q
Sbjct: 463 FVVMRGEFDSLLQWPFRQRVTLMLLDQ 489
>sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2
          Length = 501

 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 39/89 (43%), Positives = 54/89 (60%)
 Frame = +3

Query: 639 GEFIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRVDPDGDGSAKGTHLSLYY 818
           G FIW+             G    I+S +FYT ++GYKMCLRV  +GDG+ +GTHLSL++
Sbjct: 352 GVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFF 411

Query: 819 CLMKGEFDDILEWSFKFDLTLSLIDQQTR 905
            +MKG  D +L+W F   +TL L+D   R
Sbjct: 412 VVMKGPNDALLQWPFNQKVTLMLLDHNNR 440

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 32/86 (37%), Positives = 46/86 (53%)
 Frame = +3

Query: 135 NGEFVWIIDKISEKMKDAKNGINTTIYSDSFYTHKNGYKMCLSAEPDGFDEDKGNLCFVL 314
           +G F+W I   + K ++A  G    I+S +FYT + GYKMCL    +G    +G    + 
Sbjct: 351 DGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLF 410

Query: 315 FHLMKGEFDDDLMWPFAFDVTFSLIN 392
           F +MKG  D  L WPF   VT  L++
Sbjct: 411 FVVMKGPNDALLQWPFNQKVTLMLLD 436
>sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84)
          Length = 557

 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 37/86 (43%), Positives = 55/86 (63%)
 Frame = +3

Query: 639 GEFIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRVDPDGDGSAKGTHLSLYY 818
           G+ IW+            +G    I+S SFYT + GY++C R   +GDGS +G+HLSLY+
Sbjct: 404 GKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYF 463

Query: 819 CLMKGEFDDILEWSFKFDLTLSLIDQ 896
            +M+GEFD +L+W F+  +TL L+DQ
Sbjct: 464 VVMRGEFDSLLQWPFRQRVTLMLLDQ 489

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
 Frame = +3

Query: 12  ITNMKNVENKFANAMEERINKEKDLMKLSK--IVENEDT-----PTLTNGEFVWIIDKIS 170
           IT ++N + + A  +EE  NK    + + K  + +NE+       T  NG+ +W +    
Sbjct: 356 ITLLENNDQRLA-VLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYK 414

Query: 171 EKMKDAKNGINTTIYSDSFYTHKNGYKMCLSAEPDGFDEDKGNLCFVLFHLMKGEFDDDL 350
            K ++A +G   +I+S SFYT + GY++C  A  +G    +G+   + F +M+GEFD  L
Sbjct: 415 MKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLL 474

Query: 351 MWPFAFDVTFSLINQ 395
            WPF   VT  L++Q
Sbjct: 475 QWPFRQRVTLMLLDQ 489
>sp|Q12933|TRAF2_HUMAN TNF receptor-associated factor 2 (Tumor necrosis factor type 2
           receptor-associated protein 3)
          Length = 501

 Score = 83.6 bits (205), Expect = 7e-16
 Identities = 39/89 (43%), Positives = 54/89 (60%)
 Frame = +3

Query: 639 GEFIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRVDPDGDGSAKGTHLSLYY 818
           G FIW+             G    I+S +FYT ++GYKMCLR+  +GDG+ +GTHLSL++
Sbjct: 352 GVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFF 411

Query: 819 CLMKGEFDDILEWSFKFDLTLSLIDQQTR 905
            +MKG  D +L W F   +TL L+DQ  R
Sbjct: 412 VVMKGPNDALLRWPFNQKVTLMLLDQNNR 440

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 36/99 (36%), Positives = 53/99 (53%)
 Frame = +3

Query: 99  KIVENEDTPTLTNGEFVWIIDKISEKMKDAKNGINTTIYSDSFYTHKNGYKMCLSAEPDG 278
           K++E E   +  +G F+W I   + K ++A  G    I+S +FYT + GYKMCL    +G
Sbjct: 341 KVLEME--ASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNG 398

Query: 279 FDEDKGNLCFVLFHLMKGEFDDDLMWPFAFDVTFSLINQ 395
               +G    + F +MKG  D  L WPF   VT  L++Q
Sbjct: 399 DGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ 437
>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
           associated protein) (LAP1) (CAP-1)
          Length = 568

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 40/92 (43%), Positives = 52/92 (56%)
 Frame = +3

Query: 639 GEFIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRVDPDGDGSAKGTHLSLYY 818
           G  IW+             G    +YS  FYT   GYKMC RV  +GDG  KGTHLSL++
Sbjct: 416 GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFF 475

Query: 819 CLMKGEFDDILEWSFKFDLTLSLIDQQTRLAH 914
            +M+GE+D +L W FK  +TL L+DQ +   H
Sbjct: 476 VIMRGEYDALLPWPFKQKVTLMLMDQGSSRRH 507

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 32/87 (36%), Positives = 45/87 (51%)
 Frame = +3

Query: 135 NGEFVWIIDKISEKMKDAKNGINTTIYSDSFYTHKNGYKMCLSAEPDGFDEDKGNLCFVL 314
           NG  +W I     + ++A  G   ++YS  FYT   GYKMC     +G    KG    + 
Sbjct: 415 NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLF 474

Query: 315 FHLMKGEFDDDLMWPFAFDVTFSLINQ 395
           F +M+GE+D  L WPF   VT  L++Q
Sbjct: 475 FVIMRGEYDALLPWPFKQKVTLMLMDQ 501
>sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (TRAFAMN)
          Length = 567

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 40/92 (43%), Positives = 52/92 (56%)
 Frame = +3

Query: 639 GEFIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRVDPDGDGSAKGTHLSLYY 818
           G  IW+             G    +YS  FYT   GYKMC RV  +GDG  KGTHLSL++
Sbjct: 415 GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFF 474

Query: 819 CLMKGEFDDILEWSFKFDLTLSLIDQQTRLAH 914
            +M+GE+D +L W FK  +TL L+DQ +   H
Sbjct: 475 VIMRGEYDALLPWPFKQKVTLMLMDQGSSRRH 506

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 32/87 (36%), Positives = 45/87 (51%)
 Frame = +3

Query: 135 NGEFVWIIDKISEKMKDAKNGINTTIYSDSFYTHKNGYKMCLSAEPDGFDEDKGNLCFVL 314
           NG  +W I     + ++A  G   ++YS  FYT   GYKMC     +G    KG    + 
Sbjct: 414 NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLF 473

Query: 315 FHLMKGEFDDDLMWPFAFDVTFSLINQ 395
           F +M+GE+D  L WPF   VT  L++Q
Sbjct: 474 FVIMRGEYDALLPWPFKQKVTLMLMDQ 500
>sp|P39428|TRAF1_MOUSE TNF receptor-associated factor 1
          Length = 409

 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 37/89 (41%), Positives = 54/89 (60%)
 Frame = +3

Query: 639 GEFIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRVDPDGDGSAKGTHLSLYY 818
           G F+W+             G    ++S +FYT K+GYK+CLR+  +GDGS K THLSL+ 
Sbjct: 260 GTFLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFI 319

Query: 819 CLMKGEFDDILEWSFKFDLTLSLIDQQTR 905
            +M+GE+D +L W F+  +T  L+DQ  R
Sbjct: 320 VIMRGEYDALLPWPFRNKVTFMLLDQNNR 348

 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 35/126 (27%), Positives = 66/126 (52%)
 Frame = +3

Query: 18  NMKNVENKFANAMEERINKEKDLMKLSKIVENEDTPTLTNGEFVWIIDKISEKMKDAKNG 197
           ++ ++E +     +    K++ L KL   +   +  +  +G F+W I  ++++  ++  G
Sbjct: 221 HLLSLEQRVVELQQTLAQKDQVLGKLEHSLRLMEEASF-DGTFLWKITNVTKRCHESVCG 279

Query: 198 INTTIYSDSFYTHKNGYKMCLSAEPDGFDEDKGNLCFVLFHLMKGEFDDDLMWPFAFDVT 377
              +++S +FYT K GYK+CL    +G    K     +   +M+GE+D  L WPF   VT
Sbjct: 280 RTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVT 339

Query: 378 FSLINQ 395
           F L++Q
Sbjct: 340 FMLLDQ 345
>sp|Q13077|TRAF1_HUMAN TNF receptor-associated factor 1 (Epstein-Barr virus-induced
           protein 6)
          Length = 416

 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 36/89 (40%), Positives = 54/89 (60%)
 Frame = +3

Query: 639 GEFIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRVDPDGDGSAKGTHLSLYY 818
           G F+W+             G    ++S +FYT K+GYK+CLR+  +GDG+ K THLSL+ 
Sbjct: 267 GTFLWKITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFI 326

Query: 819 CLMKGEFDDILEWSFKFDLTLSLIDQQTR 905
            +M+GE+D +L W F+  +T  L+DQ  R
Sbjct: 327 VIMRGEYDALLPWPFRNKVTFMLLDQNNR 355

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 35/123 (28%), Positives = 64/123 (52%)
 Frame = +3

Query: 27  NVENKFANAMEERINKEKDLMKLSKIVENEDTPTLTNGEFVWIIDKISEKMKDAKNGINT 206
           ++E +     +    K++ L KL + +   +  +  +G F+W I  ++ +  ++  G   
Sbjct: 231 SLEQRVVELQQTLAQKDQALGKLEQSLRLMEEASF-DGTFLWKITNVTRRCHESACGRTV 289

Query: 207 TIYSDSFYTHKNGYKMCLSAEPDGFDEDKGNLCFVLFHLMKGEFDDDLMWPFAFDVTFSL 386
           +++S +FYT K GYK+CL    +G    K     +   +M+GE+D  L WPF   VTF L
Sbjct: 290 SLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFML 349

Query: 387 INQ 395
           ++Q
Sbjct: 350 LDQ 352
>sp|Q9BUZ4|TRAF4_HUMAN TNF receptor-associated factor 4 (Cysteine-rich domain associated
           with RING and Traf domains protein 1) (Malignant 62)
           (RING finger protein 83)
          Length = 470

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 38/103 (36%), Positives = 59/103 (57%), Gaps = 3/103 (2%)
 Frame = +3

Query: 597 ELLKIKMDQHKLNFGE---FIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRV 767
           EL +++ +  +L+ G     IW+               N   +S +FYTHK+GYK+ +  
Sbjct: 291 ELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSA 350

Query: 768 DPDGDGSAKGTHLSLYYCLMKGEFDDILEWSFKFDLTLSLIDQ 896
             +G+GS +GTHLSLY  ++ G FD++LEW F   +T SL+DQ
Sbjct: 351 FLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQ 393

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 37/108 (34%), Positives = 62/108 (57%)
 Frame = +3

Query: 72  KEKDLMKLSKIVENEDTPTLTNGEFVWIIDKISEKMKDAKNGINTTIYSDSFYTHKNGYK 251
           + ++L +L +  E E+    ++G  +W I     ++++AK   N   +S +FYTHK GYK
Sbjct: 288 QRQELQELRR--ELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYK 345

Query: 252 MCLSAEPDGFDEDKGNLCFVLFHLMKGEFDDDLMWPFAFDVTFSLINQ 395
           + +SA  +G    +G    +   ++ G FD+ L WPFA  VTFSL++Q
Sbjct: 346 LQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQ 393
>sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 (Cysteine-rich motif associated to
           RING and Traf domains protein 1)
          Length = 470

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 36/103 (34%), Positives = 58/103 (56%), Gaps = 3/103 (2%)
 Frame = +3

Query: 597 ELLKIKMDQHKLNFGE---FIWRXXXXXXXXXXXXNGINKIIYSDSFYTHKHGYKMCLRV 767
           EL +++ +  +L+ G     IW+               N   +S +FYTHK+GYK+ +  
Sbjct: 291 ELQELRRELEELSIGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSA 350

Query: 768 DPDGDGSAKGTHLSLYYCLMKGEFDDILEWSFKFDLTLSLIDQ 896
             +G+GS +GTHLS+Y  ++ G FD++LEW     +T SL+DQ
Sbjct: 351 SLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPLARRVTFSLLDQ 393

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 36/108 (33%), Positives = 61/108 (56%)
 Frame = +3

Query: 72  KEKDLMKLSKIVENEDTPTLTNGEFVWIIDKISEKMKDAKNGINTTIYSDSFYTHKNGYK 251
           + ++L +L +  E E+    ++G  +W I     ++++AK   N   +S +FYTHK GYK
Sbjct: 288 QRQELQELRR--ELEELSIGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYK 345

Query: 252 MCLSAEPDGFDEDKGNLCFVLFHLMKGEFDDDLMWPFAFDVTFSLINQ 395
           + +SA  +G    +G    +   ++ G FD+ L WP A  VTFSL++Q
Sbjct: 346 LQVSASLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPLARRVTFSLLDQ 393
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,572,653
Number of Sequences: 369166
Number of extensions: 1650953
Number of successful extensions: 4321
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4054
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4315
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9318621220
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)