Planaria EST Database


DrC_02606

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02606
         (744 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q02253|MMSA_RAT  Methylmalonate-semialdehyde dehydrogenas...   263   4e-70
sp|Q02252|MMSA_HUMAN  Methylmalonate-semialdehyde dehydrogen...   261   1e-69
sp|Q07536|MMSA_BOVIN  Methylmalonate-semialdehyde dehydrogen...   257   2e-68
sp|P52713|MMSA_CAEEL  Probable methylmalonate-semialdehyde d...   254   1e-67
sp|P28810|MMSA_PSEAE  Methylmalonate-semialdehyde dehydrogen...   174   2e-43
sp|P42412|MMSA_BACSU  Probable methylmalonate-semialdehyde d...   171   2e-42
sp|P42236|ALDH1_BACSU  Probable aldehyde dehydrogenase ycbD       119   1e-26
sp|P24549|AL1A1_MOUSE  Retinal dehydrogenase 1 (RalDH1) (RAL...   115   1e-25
sp|P51647|AL1A1_RAT  Retinal dehydrogenase 1 (RalDH1) (RALDH...   114   2e-25
sp|Q8MI17|AL1A1_RABIT  Retinal dehydrogenase 1 (RalDH1) (RAL...   114   4e-25
>sp|Q02253|MMSA_RAT Methylmalonate-semialdehyde dehydrogenase [acylating],
           mitochondrial precursor (MMSDH) (Malonate-semialdehyde
           dehydrogenase [acylating])
          Length = 535

 Score =  263 bits (672), Expect = 4e-70
 Identities = 120/196 (61%), Positives = 161/196 (82%)
 Frame = +3

Query: 126 STGIPKTKLFINGEFVESQATEWIDVLNPATNEVVTLVPKSTNSEMESAVKSCIKAFESW 305
           S+ +P  KLFI+G+FVES++ +WID+ NPATNEVV  VP+ST +EME+AV +C +AF +W
Sbjct: 34  SSSVPTVKLFIDGKFVESKSDKWIDIHNPATNEVVGRVPQSTKAEMEAAVAACKRAFPAW 93

Query: 306 SLRSVLNRQQYMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRGLQVVEHCCSITN 485
           +  S+L+RQQ + + Q+LIK +LK+IA+ IT++QGKT  DAEGDV RGLQVVEH CS+T+
Sbjct: 94  ADTSILSRQQVLLRYQQLIKENLKEIARLITLEQGKTLADAEGDVFRGLQVVEHACSVTS 153

Query: 486 LQLGETMPGVAKDLDIVSYKEPIGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSER 665
           L LGETMP + KD+D+ SY+ P+GV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER
Sbjct: 154 LMLGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSER 213

Query: 666 DPGAAMMLMELCVEAG 713
            PGA M+L +L  ++G
Sbjct: 214 VPGATMLLAKLLQDSG 229
>sp|Q02252|MMSA_HUMAN Methylmalonate-semialdehyde dehydrogenase [acylating],
           mitochondrial precursor (MMSDH) (Malonate-semialdehyde
           dehydrogenase [acylating])
          Length = 535

 Score =  261 bits (668), Expect = 1e-69
 Identities = 118/196 (60%), Positives = 160/196 (81%)
 Frame = +3

Query: 126 STGIPKTKLFINGEFVESQATEWIDVLNPATNEVVTLVPKSTNSEMESAVKSCIKAFESW 305
           S+ +P  KLFI G+FVES++ +WID+ NPATNEV+  VP++T +EM++A+ SC +AF +W
Sbjct: 34  SSSVPTVKLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAW 93

Query: 306 SLRSVLNRQQYMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRGLQVVEHCCSITN 485
           +  SVL+RQQ + + Q+LIK +LK+IAK IT++QGKT  DAEGDV RGLQVVEH CS+T+
Sbjct: 94  ADTSVLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTS 153

Query: 486 LQLGETMPGVAKDLDIVSYKEPIGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSER 665
           L +GETMP + KD+D+ SY+ P+GV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER
Sbjct: 154 LMMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSER 213

Query: 666 DPGAAMMLMELCVEAG 713
            PGA M+L +L  ++G
Sbjct: 214 VPGATMLLAKLLQDSG 229
>sp|Q07536|MMSA_BOVIN Methylmalonate-semialdehyde dehydrogenase [acylating],
           mitochondrial precursor (MMSDH) (Malonate-semialdehyde
           dehydrogenase [acylating])
          Length = 537

 Score =  257 bits (657), Expect = 2e-68
 Identities = 115/196 (58%), Positives = 159/196 (81%)
 Frame = +3

Query: 126 STGIPKTKLFINGEFVESQATEWIDVLNPATNEVVTLVPKSTNSEMESAVKSCIKAFESW 305
           S+ +P  KLFI+G+F+ES++ +WID+ NPATNEV+  VP+ST +EM++AV SC + F +W
Sbjct: 36  SSSVPTVKLFIDGKFIESKSDKWIDIHNPATNEVIGRVPESTKAEMDAAVSSCKRTFPAW 95

Query: 306 SLRSVLNRQQYMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRGLQVVEHCCSITN 485
           +  S+L+RQQ + + Q+LIK +LK+IA+ I ++QGKT  DAEGDV RGLQVVEH CS+T+
Sbjct: 96  ADTSILSRQQVLLRYQQLIKENLKEIARLIMLEQGKTLADAEGDVFRGLQVVEHACSVTS 155

Query: 486 LQLGETMPGVAKDLDIVSYKEPIGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSER 665
           L LG+TMP + KD+D+ SY+ P+GV AGI PFNFPAMIPLWMFP+++VCGNT ++KPSER
Sbjct: 156 LMLGDTMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSER 215

Query: 666 DPGAAMMLMELCVEAG 713
            PGA M+L +L  ++G
Sbjct: 216 VPGATMLLAKLFQDSG 231
>sp|P52713|MMSA_CAEEL Probable methylmalonate-semialdehyde dehydrogenase [acylating],
           mitochondrial precursor (MMSDH) (Malonate-semialdehyde
           dehydrogenase [acylating])
          Length = 523

 Score =  254 bits (650), Expect = 1e-67
 Identities = 119/192 (61%), Positives = 156/192 (81%)
 Frame = +3

Query: 138 PKTKLFINGEFVESQATEWIDVLNPATNEVVTLVPKSTNSEMESAVKSCIKAFESWSLRS 317
           P  KL+I+G+ VES+ T+++++ NPATNEV+ +VP +T +EM++AV S   AF +W   S
Sbjct: 28  PTVKLWIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAFNTWKNTS 87

Query: 318 VLNRQQYMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRGLQVVEHCCSITNLQLG 497
            L RQQ MFKLQ LIKRD+KK+A++ITI+QGKT  DAEGDV RGLQVVEH CS+ +L +G
Sbjct: 88  PLTRQQCMFKLQALIKRDMKKLAESITIEQGKTLPDAEGDVSRGLQVVEHACSVPSLMMG 147

Query: 498 ETMPGVAKDLDIVSYKEPIGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGA 677
           ET+P V++D+D  SY+ P+GVTAGI PFNFPAMIPLWMFP++L  GNTM++KPSE+DPGA
Sbjct: 148 ETLPNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGA 207

Query: 678 AMMLMELCVEAG 713
           A +L+EL  EAG
Sbjct: 208 AQLLVELAKEAG 219
>sp|P28810|MMSA_PSEAE Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH)
          Length = 497

 Score =  174 bits (441), Expect = 2e-43
 Identities = 86/186 (46%), Positives = 121/186 (65%)
 Frame = +3

Query: 156 INGEFVESQATEWIDVLNPATNEVVTLVPKSTNSEMESAVKSCIKAFESWSLRSVLNRQQ 335
           I G FVE    + I V NP  N  +  +  ++  ++E AV S  + F SW    V  R +
Sbjct: 9   IAGAFVEGLGAQRIPVSNPLDNSTLAEIACASAEQVEQAVASARETFASWKETPVSERAR 68

Query: 336 YMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRGLQVVEHCCSITNLQLGETMPGV 515
            M + Q L+K    ++AK ++ + GKTF DA+GDV RG++VVEH C++ +L +GET+  V
Sbjct: 69  VMLRYQALLKEHHDELAKIVSSELGKTFEDAKGDVWRGIEVVEHACNVPSLLMGETVENV 128

Query: 516 AKDLDIVSYKEPIGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGAAMMLME 695
           A+++D  S  +P+GV  GITPFNFPAMIPLWMFPL++ CGN  ILKPSE+ P  ++ L E
Sbjct: 129 ARNIDTYSITQPLGVCVGITPFNFPAMIPLWMFPLAIACGNAFILKPSEQVPLTSVRLAE 188

Query: 696 LCVEAG 713
           L +EAG
Sbjct: 189 LFLEAG 194
>sp|P42412|MMSA_BACSU Probable methylmalonate-semialdehyde dehydrogenase [acylating]
           (MMSDH)
          Length = 487

 Score =  171 bits (433), Expect = 2e-42
 Identities = 83/193 (43%), Positives = 128/193 (66%)
 Frame = +3

Query: 135 IPKTKLFINGEFVESQATEWIDVLNPATNEVVTLVPKSTNSEMESAVKSCIKAFESWSLR 314
           I K K +INGE+VES+  ++ DV+NPAT EV+  VP ST  +++ A ++  +AF++WS  
Sbjct: 4   IRKLKNYINGEWVESKTDQYEDVVNPATKEVLCQVPISTKEDIDYAAQTAAEAFKTWSKV 63

Query: 315 SVLNRQQYMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRGLQVVEHCCSITNLQL 494
           +V  R + +F  Q+L+ +  +++A  ITI+ GK   +A G+V RG++ VE      +L +
Sbjct: 64  AVPRRARILFNFQQLLSQHKEELAHLITIENGKNTKEALGEVGRGIENVEFAAGAPSLMM 123

Query: 495 GETMPGVAKDLDIVSYKEPIGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPG 674
           G+++  +A D++  +Y+ PIGV  GI PFNFP M+P WMFP+++  GNT ILKPSER P 
Sbjct: 124 GDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPSERTPL 183

Query: 675 AAMMLMELCVEAG 713
               L+EL  +AG
Sbjct: 184 LTEKLVELFEKAG 196
>sp|P42236|ALDH1_BACSU Probable aldehyde dehydrogenase ycbD
          Length = 488

 Score =  119 bits (297), Expect = 1e-26
 Identities = 62/188 (32%), Positives = 109/188 (57%), Gaps = 1/188 (0%)
 Frame = +3

Query: 153 FINGEFVESQATEWIDVLNPA-TNEVVTLVPKSTNSEMESAVKSCIKAFESWSLRSVLNR 329
           FINGE+V+SQ+ + + V NPA  N++V  V  ST  ++E AV +  +A  +W   +   R
Sbjct: 13  FINGEWVKSQSGDMVKVENPADVNDIVGYVQNSTAEDVERAVTAANEAKTAWRKLTGAER 72

Query: 330 QQYMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRGLQVVEHCCSITNLQLGETMP 509
            QY++K  +++++ L++IA   T + GKT  +A+G+  RG+ ++ +       + G+ +P
Sbjct: 73  GQYLYKTADIMEQRLEEIAACATREMGKTLPEAKGETARGIAILRYYAGEGMRKTGDVIP 132

Query: 510 GVAKDLDIVSYKEPIGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKPSERDPGAAMML 689
              KD  + + + P+GV   I+P+NFP  IP+W    +LV GNT+++KP+         +
Sbjct: 133 STDKDALMFTTRVPLGVVGVISPWNFPVAIPIWKMAPALVYGNTVVIKPATETAVTCAKI 192

Query: 690 MELCVEAG 713
           +    EAG
Sbjct: 193 IACFEEAG 200
>sp|P24549|AL1A1_MOUSE Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
           family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
           (ALHDII) (ALDH-E1)
          Length = 501

 Score =  115 bits (288), Expect = 1e-25
 Identities = 71/200 (35%), Positives = 113/200 (56%), Gaps = 6/200 (3%)
 Frame = +3

Query: 135 IPKTKLFINGEFVESQATEWIDVLNPATNEVVTLVPKSTNSEMESAVKSCIKAFE---SW 305
           I  TK+FIN E+  S + +   VLNPAT EV+  V +   ++++ AVK+  +AF+    W
Sbjct: 18  IQHTKIFINNEWHNSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPW 77

Query: 306 SLRSVLNRQQYMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRG-LQVVEHCCSIT 482
                  R + + KL +L++RD   +A    +  GK F +A    L G ++ +++C    
Sbjct: 78  RTMDASERGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWA 137

Query: 483 NLQLGETMPGVAKDLDIVSY--KEPIGVTAGITPFNFPAMIPLWMFPLSLVCGNTMILKP 656
           +   G+T+P    D DI +Y  +EPIGV   I P+NFP ++ +W    +L CGNT+++KP
Sbjct: 138 DKIHGQTIPS---DGDIFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKP 194

Query: 657 SERDPGAAMMLMELCVEAGF 716
           +E+ P  A+ L  L  EAGF
Sbjct: 195 AEQTPLTALHLASLIKEAGF 214
>sp|P51647|AL1A1_RAT Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
           family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
           (ALHDII) (ALDH-E1)
          Length = 501

 Score =  114 bits (286), Expect = 2e-25
 Identities = 71/205 (34%), Positives = 116/205 (56%), Gaps = 6/205 (2%)
 Frame = +3

Query: 120 LLSTGIPKTKLFINGEFVESQATEWIDVLNPATNEVVTLVPKSTNSEMESAVKSCIKAFE 299
           L +  I  TK+FIN E+ +S + +   VLNPAT EV+  V +   ++++ AVK+  +AF+
Sbjct: 13  LANLKIQHTKIFINNEWHDSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQ 72

Query: 300 ---SWSLRSVLNRQQYMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRG-LQVVEH 467
               W       R + + KL +L++RD   +A    I  GK F +A    L G ++ +++
Sbjct: 73  IGSPWRTMDASERGRLLNKLADLMERDRLLLATIEAINGGKVFANAYLSDLGGSIKALKY 132

Query: 468 CCSITNLQLGETMPGVAKDLDIVSY--KEPIGVTAGITPFNFPAMIPLWMFPLSLVCGNT 641
           C    +   G+T+P    D DI ++  +EPIGV   I P+NFP ++ +W    +L CGNT
Sbjct: 133 CAGWADKIHGQTIPS---DGDIFTFTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNT 189

Query: 642 MILKPSERDPGAAMMLMELCVEAGF 716
           +++KP+E+ P  A+ +  L  EAGF
Sbjct: 190 VVVKPAEQTPLTALHMASLIKEAGF 214
>sp|Q8MI17|AL1A1_RABIT Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
           family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
           (ALHDII) (ALDH-E1)
          Length = 496

 Score =  114 bits (284), Expect = 4e-25
 Identities = 71/205 (34%), Positives = 113/205 (55%), Gaps = 6/205 (2%)
 Frame = +3

Query: 120 LLSTGIPKTKLFINGEFVESQATEWIDVLNPATNEVVTLVPKSTNSEMESAVKSCIKAFE 299
           L +  I  TK+FIN E+ +S + +   VLNPAT E + L+ +   ++++ AVK+  +AF+
Sbjct: 8   LTNLKIQYTKIFINNEWHDSVSGKKFPVLNPATEEQICLIEEGDKADVDKAVKAARQAFQ 67

Query: 300 ---SWSLRSVLNRQQYMFKLQELIKRDLKKIAKNITIQQGKTFGDAEGDVLRG-LQVVEH 467
               W       R + ++KL +LI+RD   +A   ++  GK F +A    L G ++ + +
Sbjct: 68  IGSPWRTMDASERGRLLYKLADLIERDRLLLATMESLNAGKLFPNAYLMDLGGCIKTLRY 127

Query: 468 CCSITNLQLGETMPGVAKDLDIVSYK--EPIGVTAGITPFNFPAMIPLWMFPLSLVCGNT 641
           C    +   G TMP    D D   Y   EP+GV   I P+NFP ++ +W    +L CGNT
Sbjct: 128 CAGWADKIQGRTMP---MDGDFFCYTRHEPVGVCGQIIPWNFPLVMLIWKIGPALSCGNT 184

Query: 642 MILKPSERDPGAAMMLMELCVEAGF 716
           +I+KP+E+ P  A+ +  L  EAGF
Sbjct: 185 VIVKPAEQTPLTALHVASLIKEAGF 209
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,505,453
Number of Sequences: 369166
Number of extensions: 1769058
Number of successful extensions: 5100
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4812
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4969
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6728100400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)