Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02602 (741 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q5R8E4|FA82B_PONPY Protein FAM82B 149 1e-35 sp|Q96DB5|FA82B_HUMAN Protein FAM82B 148 2e-35 sp|Q9DCV4|FA82B_MOUSE Protein FAM82B 147 2e-35 sp|Q07963|UBR2_YEAST Ubiquitin-protein ligase E3 UBR2 (Ubiq... 34 0.36 sp|O75934|BCAS2_HUMAN Breast carcinoma amplified sequence 2... 33 0.61 sp|Q5RAX7|BCAS2_PONPY Breast carcinoma amplified sequence 2... 33 0.61 sp|P70718|6PGD_ACTAC 6-phosphogluconate dehydrogenase, deca... 31 4.0 sp|P35601|RFC1_MOUSE Activator 1 140 kDa subunit (Replicati... 30 6.8 sp|P55517|Y4JQ_RHISN Hypothetical 115.9 kDa protein y4jQ 30 8.8
>sp|Q5R8E4|FA82B_PONPY Protein FAM82B Length = 314 Score = 149 bits (375), Expect = 1e-35 Identities = 72/164 (43%), Positives = 105/164 (64%), Gaps = 1/164 (0%) Frame = +2 Query: 251 EYKSPELMWRNARALREMANNTKDKAEHKNLL-YEGLEIAKNCLEIDENNSGCNKWYAYL 427 E + EL+WR ARA R++A ++ E K LL YE LE AK LE +E++ +KWYA Sbjct: 111 ESEDAELLWRLARASRDVAQLSRTSEEEKKLLVYEALEYAKRALEKNESSFAAHKWYAIC 170 Query: 428 LDLTGRVEGIKKRIENSYAVKKHLDIASEKSNGTDTGALHALGVWCYEIAALSWLNRKLA 607 L G EGIK +I N+Y +K+H + A E N D ++H +G+WCY A + W R++A Sbjct: 171 LSDVGDYEGIKAKIANAYIIKEHFEKAIEL-NPKDATSIHLMGIWCYTFAEMPWYQRRIA 229 Query: 608 STFFATPPTSTYQESLNYLMAAEKISPGFYSQNYLYIGKVFEKI 739 FATPP+STY+++L+Y AE++ P FYS+N L +GK + K+ Sbjct: 230 KMLFATPPSSTYEKALSYFHRAEQVDPNFYSKNLLLLGKTYLKL 273
>sp|Q96DB5|FA82B_HUMAN Protein FAM82B Length = 314 Score = 148 bits (373), Expect = 2e-35 Identities = 72/164 (43%), Positives = 104/164 (63%), Gaps = 1/164 (0%) Frame = +2 Query: 251 EYKSPELMWRNARALREMANNTKDKAEHKNLL-YEGLEIAKNCLEIDENNSGCNKWYAYL 427 E + EL+WR ARA R++A ++ E K LL YE LE AK LE +E++ +KWYA Sbjct: 111 ESEDAELLWRLARASRDVAQLSRTSEEEKKLLVYEALEYAKRALEKNESSFASHKWYAIC 170 Query: 428 LDLTGRVEGIKKRIENSYAVKKHLDIASEKSNGTDTGALHALGVWCYEIAALSWLNRKLA 607 L G EGIK +I N+Y +K+H + A E N D ++H +G+WCY A + W R++A Sbjct: 171 LSDVGDYEGIKAKIANAYIIKEHFEKAIEL-NPKDATSIHLMGIWCYTFAEMPWYQRRIA 229 Query: 608 STFFATPPTSTYQESLNYLMAAEKISPGFYSQNYLYIGKVFEKI 739 FATPP+STY+++L Y AE++ P FYS+N L +GK + K+ Sbjct: 230 KMLFATPPSSTYEKALGYFHRAEQVDPNFYSKNLLLLGKTYLKL 273
>sp|Q9DCV4|FA82B_MOUSE Protein FAM82B Length = 305 Score = 147 bits (372), Expect = 2e-35 Identities = 71/164 (43%), Positives = 103/164 (62%), Gaps = 1/164 (0%) Frame = +2 Query: 251 EYKSPELMWRNARALREMANNTKDKAEHKNLL-YEGLEIAKNCLEIDENNSGCNKWYAYL 427 E + EL+WR ARA R++A +K E K +L YE L+ AK LE E++S +KWYA Sbjct: 106 ESEDGELLWRLARASRDIAQLSKTSEEEKKVLVYEALDYAKRALEKKESSSAAHKWYAIC 165 Query: 428 LDLTGRVEGIKKRIENSYAVKKHLDIASEKSNGTDTGALHALGVWCYEIAALSWLNRKLA 607 + G EGIK +I N+Y +K+H + A E N D ++H +G+WCY A + W R++A Sbjct: 166 ISDVGDYEGIKVKIANAYVIKEHFEKAIEL-NPKDATSIHLMGIWCYTFAEMPWYQRRIA 224 Query: 608 STFFATPPTSTYQESLNYLMAAEKISPGFYSQNYLYIGKVFEKI 739 FA PP+STY+E+L Y AE++ P FYS+N L +GK + K+ Sbjct: 225 KVLFANPPSSTYEEALRYFHKAEEVDPNFYSKNLLLLGKTYLKL 268
>sp|Q07963|UBR2_YEAST Ubiquitin-protein ligase E3 UBR2 (Ubiquitin-protein ligase E3 component N-recognin-1 homolog) Length = 1872 Score = 34.3 bits (77), Expect = 0.36 Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 6/131 (4%) Frame = +2 Query: 278 RNARALREMANNTKDKA----EHKNLLYEGLEIAKNCLEIDENNSGCNKWYAYLLDLTGR 445 R + + +M N +A EH L+ L ++K L+ DE ++ C+K+ + L G+ Sbjct: 1698 RIQQVIYDMVQNINTRAYPSPEHIQLIELPLNLSKFSLDNDEISNKCDKYEIAVCLLCGQ 1757 Query: 446 VEGIKKRIENSYAVKKHL--DIASEKSNGTDTGALHALGVWCYEIAALSWLNRKLASTFF 619 K I+ S A++ +L + NG + + A GV+ +L+ TF+ Sbjct: 1758 ----KCHIQKSIALQGYLQGECTDHMRNGCEITS--AYGVFLMTGTNAIYLSYGKRGTFY 1811 Query: 620 ATPPTSTYQES 652 A P S Y E+ Sbjct: 1812 AAPYLSKYGET 1822
>sp|O75934|BCAS2_HUMAN Breast carcinoma amplified sequence 2 (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27) sp|Q9D287|BCAS2_MOUSE Breast carcinoma amplified sequence 2 homolog (DNA amplified in mammary carcinoma 1 protein) Length = 225 Score = 33.5 bits (75), Expect = 0.61 Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Frame = +2 Query: 290 ALREMANNTKDKAEHKNLLYEGLEIAKNCLEIDENNSGCNKWYAYLLDLTGRVEGIKKRI 469 A +E NN+ + EH+ + E LE+ + GCN W Y +L +E +K + Sbjct: 102 AWQECVNNSMAQLEHQAVRIENLELM--------SQHGCNAWKVYNENLVHMIEHAQKEL 153 Query: 470 ENSYAVKKHL-DIASEKSN 523 + ++KH+ D+ ++ N Sbjct: 154 QK---LRKHIQDLNWQRKN 169
>sp|Q5RAX7|BCAS2_PONPY Breast carcinoma amplified sequence 2 homolog Length = 226 Score = 33.5 bits (75), Expect = 0.61 Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Frame = +2 Query: 290 ALREMANNTKDKAEHKNLLYEGLEIAKNCLEIDENNSGCNKWYAYLLDLTGRVEGIKKRI 469 A +E NN+ + EH+ + E LE+ + GCN W Y +L +E +K + Sbjct: 103 AWQECVNNSMAQLEHQAVRIENLELM--------SQHGCNAWKVYNENLVHMIEHAQKEL 154 Query: 470 ENSYAVKKHL-DIASEKSN 523 + ++KH+ D+ ++ N Sbjct: 155 QK---LRKHIQDLNWQRKN 170
>sp|P70718|6PGD_ACTAC 6-phosphogluconate dehydrogenase, decarboxylating Length = 484 Score = 30.8 bits (68), Expect = 4.0 Identities = 22/70 (31%), Positives = 34/70 (48%) Frame = +2 Query: 329 EHKNLLYEGLEIAKNCLEIDENNSGCNKWYAYLLDLTGRVEGIKKRIENSYAVKKHLDIA 508 E L EG+ ++ + L+ N + +YL+D+T + G K + S V K LD A Sbjct: 201 EAYQFLKEGVGLSDDELQATFNEWRNTELDSYLIDITADILGYKD-ADGSRLVDKVLDTA 259 Query: 509 SEKSNGTDTG 538 +K G TG Sbjct: 260 GQKGTGKWTG 269
>sp|P35601|RFC1_MOUSE Activator 1 140 kDa subunit (Replication factor C large subunit) (A1 140 kDa subunit) (RF-C 140 kDa subunit) (Activator 1 large subunit) (A1-P145) (Differentiation-specific element binding protein) (ISRE-binding protein) Length = 1131 Score = 30.0 bits (66), Expect = 6.8 Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 34/190 (17%) Frame = +2 Query: 260 SPELMWRNARALRE---MANNTKDKAEHKNL--LYEGLEIAKNCLEIDENNSGCNKWYAY 424 +P + R+A + E MA N +D+ + L L + +I C+ D N+ Y Sbjct: 692 APSVSARHALIMDEVDGMAGN-EDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHY 750 Query: 425 LLDLT---GRVEGIKKRIENSYAVKKHLDIASEKSNGTDTGA-------LHALGVWCYEI 574 DL RVE IK + S A K+ L I N GA LH L +WC + Sbjct: 751 CFDLRFQRPRVEQIKSAML-SIAFKEGLKIPPPAMNEIILGANQDVRQVLHNLSMWCAQS 809 Query: 575 AALSWLNRKLAS----------TFFATPPTSTYQESLNYLMAAEK---------ISPGFY 697 AL++ K S F T E ++ +K I+P F Sbjct: 810 KALTYDQAKADSQRAKKDIRLGPFDVTRKVFAAGEETAHMSLMDKSDLFFHDYSIAPLFV 869 Query: 698 SQNYLYIGKV 727 +NYL++ V Sbjct: 870 QENYLHVKPV 879
>sp|P55517|Y4JQ_RHISN Hypothetical 115.9 kDa protein y4jQ Length = 1039 Score = 29.6 bits (65), Expect = 8.8 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Frame = +2 Query: 212 EQCDLFKNRYHSDEYKSPELMWRNARALREMANNTKD-KAEHKNLLYEGLEIAKNCLEID 388 +Q + N + SD+ S + R E+ ++T D +A K L E +E ++ + + Sbjct: 250 DQYEFLANLFTSDQSLSKPDVLPFGRDFVEILSSTGDWRASPKAALAERVEPSRFTIPL- 308 Query: 389 ENNSGCNKWYAYLLDLTGRVEGIKKRIENSYAV 487 N+W YLLD G ++G+ + + + Sbjct: 309 -----LNRWCGYLLDSIGILDGVSSAPDREFDI 336
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 73,286,697 Number of Sequences: 369166 Number of extensions: 1311500 Number of successful extensions: 3147 Number of sequences better than 10.0: 9 Number of HSP's better than 10.0 without gapping: 3081 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3138 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6679696800 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)