Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_N03
(741 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5R8E4|FA82B_PONPY Protein FAM82B 149 1e-35
sp|Q96DB5|FA82B_HUMAN Protein FAM82B 148 2e-35
sp|Q9DCV4|FA82B_MOUSE Protein FAM82B 147 2e-35
sp|Q07963|UBR2_YEAST Ubiquitin-protein ligase E3 UBR2 (Ubiq... 34 0.36
sp|O75934|BCAS2_HUMAN Breast carcinoma amplified sequence 2... 33 0.61
sp|Q5RAX7|BCAS2_PONPY Breast carcinoma amplified sequence 2... 33 0.61
sp|P70718|6PGD_ACTAC 6-phosphogluconate dehydrogenase, deca... 31 4.0
sp|P35601|RFC1_MOUSE Activator 1 140 kDa subunit (Replicati... 30 6.8
sp|P55517|Y4JQ_RHISN Hypothetical 115.9 kDa protein y4jQ 30 8.8
>sp|Q5R8E4|FA82B_PONPY Protein FAM82B
Length = 314
Score = 149 bits (375), Expect = 1e-35
Identities = 72/164 (43%), Positives = 105/164 (64%), Gaps = 1/164 (0%)
Frame = +2
Query: 251 EYKSPELMWRNARALREMANNTKDKAEHKNLL-YEGLEIAKNCLEIDENNSGCNKWYAYL 427
E + EL+WR ARA R++A ++ E K LL YE LE AK LE +E++ +KWYA
Sbjct: 111 ESEDAELLWRLARASRDVAQLSRTSEEEKKLLVYEALEYAKRALEKNESSFAAHKWYAIC 170
Query: 428 LDLTGRVEGIKKRIENSYAVKKHLDIASEKSNGTDTGALHALGVWCYEIAALSWLNRKLA 607
L G EGIK +I N+Y +K+H + A E N D ++H +G+WCY A + W R++A
Sbjct: 171 LSDVGDYEGIKAKIANAYIIKEHFEKAIEL-NPKDATSIHLMGIWCYTFAEMPWYQRRIA 229
Query: 608 STFFATPPTSTYQESLNYLMAAEKISPGFYSQNYLYIGKVFEKI 739
FATPP+STY+++L+Y AE++ P FYS+N L +GK + K+
Sbjct: 230 KMLFATPPSSTYEKALSYFHRAEQVDPNFYSKNLLLLGKTYLKL 273
>sp|Q96DB5|FA82B_HUMAN Protein FAM82B
Length = 314
Score = 148 bits (373), Expect = 2e-35
Identities = 72/164 (43%), Positives = 104/164 (63%), Gaps = 1/164 (0%)
Frame = +2
Query: 251 EYKSPELMWRNARALREMANNTKDKAEHKNLL-YEGLEIAKNCLEIDENNSGCNKWYAYL 427
E + EL+WR ARA R++A ++ E K LL YE LE AK LE +E++ +KWYA
Sbjct: 111 ESEDAELLWRLARASRDVAQLSRTSEEEKKLLVYEALEYAKRALEKNESSFASHKWYAIC 170
Query: 428 LDLTGRVEGIKKRIENSYAVKKHLDIASEKSNGTDTGALHALGVWCYEIAALSWLNRKLA 607
L G EGIK +I N+Y +K+H + A E N D ++H +G+WCY A + W R++A
Sbjct: 171 LSDVGDYEGIKAKIANAYIIKEHFEKAIEL-NPKDATSIHLMGIWCYTFAEMPWYQRRIA 229
Query: 608 STFFATPPTSTYQESLNYLMAAEKISPGFYSQNYLYIGKVFEKI 739
FATPP+STY+++L Y AE++ P FYS+N L +GK + K+
Sbjct: 230 KMLFATPPSSTYEKALGYFHRAEQVDPNFYSKNLLLLGKTYLKL 273
>sp|Q9DCV4|FA82B_MOUSE Protein FAM82B
Length = 305
Score = 147 bits (372), Expect = 2e-35
Identities = 71/164 (43%), Positives = 103/164 (62%), Gaps = 1/164 (0%)
Frame = +2
Query: 251 EYKSPELMWRNARALREMANNTKDKAEHKNLL-YEGLEIAKNCLEIDENNSGCNKWYAYL 427
E + EL+WR ARA R++A +K E K +L YE L+ AK LE E++S +KWYA
Sbjct: 106 ESEDGELLWRLARASRDIAQLSKTSEEEKKVLVYEALDYAKRALEKKESSSAAHKWYAIC 165
Query: 428 LDLTGRVEGIKKRIENSYAVKKHLDIASEKSNGTDTGALHALGVWCYEIAALSWLNRKLA 607
+ G EGIK +I N+Y +K+H + A E N D ++H +G+WCY A + W R++A
Sbjct: 166 ISDVGDYEGIKVKIANAYVIKEHFEKAIEL-NPKDATSIHLMGIWCYTFAEMPWYQRRIA 224
Query: 608 STFFATPPTSTYQESLNYLMAAEKISPGFYSQNYLYIGKVFEKI 739
FA PP+STY+E+L Y AE++ P FYS+N L +GK + K+
Sbjct: 225 KVLFANPPSSTYEEALRYFHKAEEVDPNFYSKNLLLLGKTYLKL 268
>sp|Q07963|UBR2_YEAST Ubiquitin-protein ligase E3 UBR2 (Ubiquitin-protein ligase E3
component N-recognin-1 homolog)
Length = 1872
Score = 34.3 bits (77), Expect = 0.36
Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 6/131 (4%)
Frame = +2
Query: 278 RNARALREMANNTKDKA----EHKNLLYEGLEIAKNCLEIDENNSGCNKWYAYLLDLTGR 445
R + + +M N +A EH L+ L ++K L+ DE ++ C+K+ + L G+
Sbjct: 1698 RIQQVIYDMVQNINTRAYPSPEHIQLIELPLNLSKFSLDNDEISNKCDKYEIAVCLLCGQ 1757
Query: 446 VEGIKKRIENSYAVKKHL--DIASEKSNGTDTGALHALGVWCYEIAALSWLNRKLASTFF 619
K I+ S A++ +L + NG + + A GV+ +L+ TF+
Sbjct: 1758 ----KCHIQKSIALQGYLQGECTDHMRNGCEITS--AYGVFLMTGTNAIYLSYGKRGTFY 1811
Query: 620 ATPPTSTYQES 652
A P S Y E+
Sbjct: 1812 AAPYLSKYGET 1822
>sp|O75934|BCAS2_HUMAN Breast carcinoma amplified sequence 2 (DNA amplified in mammary
carcinoma 1 protein) (Spliceosome-associated protein SPF
27)
sp|Q9D287|BCAS2_MOUSE Breast carcinoma amplified sequence 2 homolog (DNA amplified in
mammary carcinoma 1 protein)
Length = 225
Score = 33.5 bits (75), Expect = 0.61
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +2
Query: 290 ALREMANNTKDKAEHKNLLYEGLEIAKNCLEIDENNSGCNKWYAYLLDLTGRVEGIKKRI 469
A +E NN+ + EH+ + E LE+ + GCN W Y +L +E +K +
Sbjct: 102 AWQECVNNSMAQLEHQAVRIENLELM--------SQHGCNAWKVYNENLVHMIEHAQKEL 153
Query: 470 ENSYAVKKHL-DIASEKSN 523
+ ++KH+ D+ ++ N
Sbjct: 154 QK---LRKHIQDLNWQRKN 169
>sp|Q5RAX7|BCAS2_PONPY Breast carcinoma amplified sequence 2 homolog
Length = 226
Score = 33.5 bits (75), Expect = 0.61
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +2
Query: 290 ALREMANNTKDKAEHKNLLYEGLEIAKNCLEIDENNSGCNKWYAYLLDLTGRVEGIKKRI 469
A +E NN+ + EH+ + E LE+ + GCN W Y +L +E +K +
Sbjct: 103 AWQECVNNSMAQLEHQAVRIENLELM--------SQHGCNAWKVYNENLVHMIEHAQKEL 154
Query: 470 ENSYAVKKHL-DIASEKSN 523
+ ++KH+ D+ ++ N
Sbjct: 155 QK---LRKHIQDLNWQRKN 170
>sp|P70718|6PGD_ACTAC 6-phosphogluconate dehydrogenase, decarboxylating
Length = 484
Score = 30.8 bits (68), Expect = 4.0
Identities = 22/70 (31%), Positives = 34/70 (48%)
Frame = +2
Query: 329 EHKNLLYEGLEIAKNCLEIDENNSGCNKWYAYLLDLTGRVEGIKKRIENSYAVKKHLDIA 508
E L EG+ ++ + L+ N + +YL+D+T + G K + S V K LD A
Sbjct: 201 EAYQFLKEGVGLSDDELQATFNEWRNTELDSYLIDITADILGYKD-ADGSRLVDKVLDTA 259
Query: 509 SEKSNGTDTG 538
+K G TG
Sbjct: 260 GQKGTGKWTG 269
>sp|P35601|RFC1_MOUSE Activator 1 140 kDa subunit (Replication factor C large subunit) (A1
140 kDa subunit) (RF-C 140 kDa subunit) (Activator 1
large subunit) (A1-P145) (Differentiation-specific
element binding protein) (ISRE-binding protein)
Length = 1131
Score = 30.0 bits (66), Expect = 6.8
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 34/190 (17%)
Frame = +2
Query: 260 SPELMWRNARALRE---MANNTKDKAEHKNL--LYEGLEIAKNCLEIDENNSGCNKWYAY 424
+P + R+A + E MA N +D+ + L L + +I C+ D N+ Y
Sbjct: 692 APSVSARHALIMDEVDGMAGN-EDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHY 750
Query: 425 LLDLT---GRVEGIKKRIENSYAVKKHLDIASEKSNGTDTGA-------LHALGVWCYEI 574
DL RVE IK + S A K+ L I N GA LH L +WC +
Sbjct: 751 CFDLRFQRPRVEQIKSAML-SIAFKEGLKIPPPAMNEIILGANQDVRQVLHNLSMWCAQS 809
Query: 575 AALSWLNRKLAS----------TFFATPPTSTYQESLNYLMAAEK---------ISPGFY 697
AL++ K S F T E ++ +K I+P F
Sbjct: 810 KALTYDQAKADSQRAKKDIRLGPFDVTRKVFAAGEETAHMSLMDKSDLFFHDYSIAPLFV 869
Query: 698 SQNYLYIGKV 727
+NYL++ V
Sbjct: 870 QENYLHVKPV 879
>sp|P55517|Y4JQ_RHISN Hypothetical 115.9 kDa protein y4jQ
Length = 1039
Score = 29.6 bits (65), Expect = 8.8
Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Frame = +2
Query: 212 EQCDLFKNRYHSDEYKSPELMWRNARALREMANNTKD-KAEHKNLLYEGLEIAKNCLEID 388
+Q + N + SD+ S + R E+ ++T D +A K L E +E ++ + +
Sbjct: 250 DQYEFLANLFTSDQSLSKPDVLPFGRDFVEILSSTGDWRASPKAALAERVEPSRFTIPL- 308
Query: 389 ENNSGCNKWYAYLLDLTGRVEGIKKRIENSYAV 487
N+W YLLD G ++G+ + + +
Sbjct: 309 -----LNRWCGYLLDSIGILDGVSSAPDREFDI 336
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,286,697
Number of Sequences: 369166
Number of extensions: 1311500
Number of successful extensions: 3147
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3081
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3138
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6679696800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)