Planaria EST Database


DrC_02594

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02594
         (312 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O08679|MARK2_RAT  Serine/threonine-protein kinase MARK2 (...    62   4e-10
sp|Q05512|MARK2_MOUSE  Serine/threonine-protein kinase MARK2...    62   4e-10
sp|Q7KZI7|MARK2_HUMAN  Serine/threonine-protein kinase MARK2...    62   4e-10
sp|Q8CIP4|MARK4_MOUSE  MAP/microtubule affinity-regulating k...    59   3e-09
sp|Q96L34|MARK4_HUMAN  MAP/microtubule affinity-regulating k...    59   3e-09
sp|Q8VHF0|MARK3_RAT  MAP/microtubule affinity-regulating kin...    58   6e-09
sp|Q03141|MARK3_MOUSE  MAP/microtubule affinity-regulating k...    58   6e-09
sp|P27448|MARK3_HUMAN  MAP/microtubule affinity-regulating k...    58   6e-09
sp|O94547|SRK1_SCHPO  Serine/threonine-protein kinase srk1 (...    57   1e-08
sp|Q8ICR0|CDPK2_PLAF7  Calcium-dependent protein kinase 2 (P...    57   1e-08
>sp|O08679|MARK2_RAT Serine/threonine-protein kinase MARK2 (MAP/microtubule
           affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1)
          Length = 722

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 35/106 (33%), Positives = 58/106 (54%), Gaps = 4/106 (3%)
 Frame = +3

Query: 6   GNKSSESLIEQ----KYKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKG 173
           G  S+ S  EQ     Y++L  +G+G F  V    + +T + VA+K IDK          
Sbjct: 37  GRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDK---------- 86

Query: 174 TEAKTKMNNIMIREAAVMQALDHPNLMKLIELIDDGKHIYLVLQFA 311
           T+  +     + RE  +M+ L+HPN++KL E+I+  K +YLV+++A
Sbjct: 87  TQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYA 132
>sp|Q05512|MARK2_MOUSE Serine/threonine-protein kinase MARK2 (MAP/microtubule
           affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1)
          Length = 776

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 35/106 (33%), Positives = 58/106 (54%), Gaps = 4/106 (3%)
 Frame = +3

Query: 6   GNKSSESLIEQ----KYKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKG 173
           G  S+ S  EQ     Y++L  +G+G F  V    + +T + VA+K IDK          
Sbjct: 37  GRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDK---------- 86

Query: 174 TEAKTKMNNIMIREAAVMQALDHPNLMKLIELIDDGKHIYLVLQFA 311
           T+  +     + RE  +M+ L+HPN++KL E+I+  K +YLV+++A
Sbjct: 87  TQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYA 132
>sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 (MAP/microtubule
           affinity-regulating kinase 2) (ELKL motif kinase) (EMK1)
           (PAR1 homolog)
          Length = 788

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 35/106 (33%), Positives = 58/106 (54%), Gaps = 4/106 (3%)
 Frame = +3

Query: 6   GNKSSESLIEQ----KYKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKG 173
           G  S+ S  EQ     Y++L  +G+G F  V    + +T + VA+K IDK          
Sbjct: 37  GRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDK---------- 86

Query: 174 TEAKTKMNNIMIREAAVMQALDHPNLMKLIELIDDGKHIYLVLQFA 311
           T+  +     + RE  +M+ L+HPN++KL E+I+  K +YLV+++A
Sbjct: 87  TQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYA 132
>sp|Q8CIP4|MARK4_MOUSE MAP/microtubule affinity-regulating kinase 4
          Length = 752

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 31/90 (34%), Positives = 50/90 (55%)
 Frame = +3

Query: 42  YKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKGTEAKTKMNNIMIREAA 221
           Y++L  +G+G F  V    + +T   VAIK IDK          T+        + RE  
Sbjct: 59  YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDK----------TQLNPSSLQKLFREVR 108

Query: 222 VMQALDHPNLMKLIELIDDGKHIYLVLQFA 311
           +M+ L+HPN++KL E+I+  K +YLV+++A
Sbjct: 109 IMKGLNHPNIVKLFEVIETEKTLYLVMEYA 138
>sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 (MAP/microtubule
           affinity-regulating kinase-like 1)
          Length = 752

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 31/90 (34%), Positives = 50/90 (55%)
 Frame = +3

Query: 42  YKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKGTEAKTKMNNIMIREAA 221
           Y++L  +G+G F  V    + +T   VAIK IDK          T+        + RE  
Sbjct: 59  YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDK----------TQLNPSSLQKLFREVR 108

Query: 222 VMQALDHPNLMKLIELIDDGKHIYLVLQFA 311
           +M+ L+HPN++KL E+I+  K +YLV+++A
Sbjct: 109 IMKGLNHPNIVKLFEVIETEKTLYLVMEYA 138
>sp|Q8VHF0|MARK3_RAT MAP/microtubule affinity-regulating kinase 3
          Length = 797

 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 30/90 (33%), Positives = 50/90 (55%)
 Frame = +3

Query: 42  YKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKGTEAKTKMNNIMIREAA 221
           Y++L  +G+G F  V    + +T   VAIK IDK          T+        + RE  
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDK----------TQLNPTSLQKLFREVR 105

Query: 222 VMQALDHPNLMKLIELIDDGKHIYLVLQFA 311
           +M+ L+HPN++KL E+I+  K +YL++++A
Sbjct: 106 IMKILNHPNIVKLFEVIETEKTLYLIMEYA 135
>sp|Q03141|MARK3_MOUSE MAP/microtubule affinity-regulating kinase 3 (MPK-10) (ELKL motif
           kinase 2)
          Length = 753

 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 30/90 (33%), Positives = 50/90 (55%)
 Frame = +3

Query: 42  YKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKGTEAKTKMNNIMIREAA 221
           Y++L  +G+G F  V    + +T   VAIK IDK          T+        + RE  
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDK----------TQLNPTSLQKLFREVR 105

Query: 222 VMQALDHPNLMKLIELIDDGKHIYLVLQFA 311
           +M+ L+HPN++KL E+I+  K +YL++++A
Sbjct: 106 IMKILNHPNIVKLFEVIETEKTLYLIMEYA 135
>sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 (Cdc25C-associated
           protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine
           protein kinase p78) (Ser/Thr protein kinase PAR-1)
           (Protein kinase STK10)
          Length = 776

 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 30/90 (33%), Positives = 50/90 (55%)
 Frame = +3

Query: 42  YKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKGTEAKTKMNNIMIREAA 221
           Y++L  +G+G F  V    + +T   VAIK IDK          T+        + RE  
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDK----------TQLNPTSLQKLFREVR 105

Query: 222 VMQALDHPNLMKLIELIDDGKHIYLVLQFA 311
           +M+ L+HPN++KL E+I+  K +YL++++A
Sbjct: 106 IMKILNHPNIVKLFEVIETEKTLYLIMEYA 135
>sp|O94547|SRK1_SCHPO Serine/threonine-protein kinase srk1 (Sty1-regulated kinase 1)
          Length = 580

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 26/92 (28%), Positives = 56/92 (60%)
 Frame = +3

Query: 36  QKYKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKGTEAKTKMNNIMIRE 215
           ++Y +L  +G+G F  V + +++ T E VAIK + +++P        + +   ++ +++E
Sbjct: 122 EQYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKE 181

Query: 216 AAVMQALDHPNLMKLIELIDDGKHIYLVLQFA 311
             +M+ + HPN+++L+E I   ++ YLVL+ A
Sbjct: 182 VQIMRRVKHPNIIQLLEFIQTPEYYYLVLELA 213
>sp|Q8ICR0|CDPK2_PLAF7 Calcium-dependent protein kinase 2 (PfCDPK2)
          Length = 509

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 30/94 (31%), Positives = 53/94 (56%), Gaps = 2/94 (2%)
 Frame = +3

Query: 30  IEQKYKILNNVGEGGFCVVMRGLNHITNEAVAIKKIDKSKPVYKKFKGTEAKTKMNNI-- 203
           +E KY I   +G+G +  V +G++ +TN+  AIK+              E K ++ NI  
Sbjct: 68  LEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKE--------------EKKDRLKNINR 113

Query: 204 MIREAAVMQALDHPNLMKLIELIDDGKHIYLVLQ 305
             +E  +M+ LDHPN++KL E  ++  +IYL+++
Sbjct: 114 FFQEIEIMKKLDHPNIVKLYETYENDNYIYLIME 147
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,667,478
Number of Sequences: 369166
Number of extensions: 485148
Number of successful extensions: 2914
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2614
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2650
length of database: 68,354,980
effective HSP length: 72
effective length of database: 55,054,060
effective search space used: 1706675860
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)